Danio rerio

125 known processes

prkci

protein kinase C, iota

(Aliases: aPKC[l],has,hal)

prkci biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 0.967
generation of neurons GO:0048699 385 0.946
regulation of macromolecule metabolic process GO:0060255 317 0.939
Human Yeast
regionalization GO:0003002 274 0.889
larval development GO:0002164 2 0.873
Worm
cell morphogenesis GO:0000902 289 0.833
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.816
Human Yeast
cell projection morphogenesis GO:0048858 244 0.785
cellular component morphogenesis GO:0032989 336 0.766
locomotion GO:0040011 313 0.752
neuron development GO:0048666 262 0.747
Human Mouse
rna biosynthetic process GO:0032774 181 0.719
Human
regulation of developmental process GO:0050793 247 0.714
Human Zebrafish Worm
cell projection organization GO:0030030 284 0.678
Human
regulation of nucleic acid templated transcription GO:1903506 213 0.655
Human
establishment of localization GO:0051234 244 0.647
regulation of rna metabolic process GO:0051252 224 0.623
Human Yeast
odontogenesis of dentin containing tooth GO:0042475 1 0.613
asymmetric protein localization GO:0008105 6 0.602
Worm
apical protein localization GO:0045176 6 0.593
cell part morphogenesis GO:0032990 246 0.587
camera type eye development GO:0043010 222 0.560
tube morphogenesis GO:0035239 349 0.559
establishment of epithelial cell polarity GO:0090162 2 0.544
regulation of biological quality GO:0065008 263 0.542
somitogenesis GO:0001756 87 0.538
cellular component movement GO:0006928 335 0.529
immune system development GO:0002520 191 0.528
Zebrafish
ameboidal type cell migration GO:0001667 143 0.520
central nervous system development GO:0007417 387 0.514
retina development in camera type eye GO:0060041 146 0.512
localization of cell GO:0051674 244 0.509
cytoskeleton organization GO:0007010 96 0.506
neuron differentiation GO:0030182 353 0.501
Human Mouse
medulla oblongata development GO:0021550 4 0.494
cell fate commitment GO:0045165 99 0.483
regulation of cellular biosynthetic process GO:0031326 245 0.482
Human
establishment of cell polarity GO:0030010 18 0.477
vasculature development GO:0001944 278 0.475
Zebrafish
heart looping GO:0001947 94 0.472
embryonic heart tube development GO:0035050 133 0.470
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.461
cell motility GO:0048870 244 0.439
gene expression GO:0010467 252 0.429
Human Yeast
chordate embryonic development GO:0043009 271 0.427
regulation of cell morphogenesis GO:0022604 42 0.419
heart morphogenesis GO:0003007 156 0.415
morphogenesis of an epithelium GO:0002009 333 0.411
neuron projection morphogenesis GO:0048812 161 0.411
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.402
regulation of neuron differentiation GO:0045664 56 0.401
Human
response to stress GO:0006950 263 0.394
regulation of cellular metabolic process GO:0031323 320 0.385
Human Yeast
positive regulation of biological process GO:0048518 253 0.367
Human Zebrafish Mouse
chemotaxis GO:0006935 104 0.363
regulation of macromolecule biosynthetic process GO:0010556 225 0.361
Human
eye development GO:0001654 277 0.360
phosphorus metabolic process GO:0006793 109 0.360
Human Yeast Mouse Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.352
cellular nitrogen compound metabolic process GO:0034641 290 0.343
Human Yeast
regulation of cell differentiation GO:0045595 142 0.339
Human
somite development GO:0061053 96 0.336
regulation of anatomical structure morphogenesis GO:0022603 130 0.329
Zebrafish
regulation of cellular component organization GO:0051128 86 0.323
Human Yeast Mouse
epithelial tube formation GO:0072175 19 0.323
developmental growth involved in morphogenesis GO:0060560 86 0.315
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.315
positive regulation of cellular process GO:0048522 201 0.311
Human
single organism transport GO:0044765 206 0.307
Zebrafish Mouse
specification of symmetry GO:0009799 204 0.305
regulation of nitrogen compound metabolic process GO:0051171 251 0.292
Human Yeast
sensory organ morphogenesis GO:0090596 200 0.291
heart jogging GO:0003146 40 0.286
odontogenesis GO:0042476 9 0.283
nucleobase containing compound metabolic process GO:0006139 274 0.281
Human Yeast
cell morphogenesis involved in differentiation GO:0000904 195 0.277
establishment of monopolar cell polarity GO:0061162 2 0.273
Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.270
axonogenesis GO:0007409 152 0.268
epithelial cell differentiation GO:0030855 116 0.267
stem cell development GO:0048864 82 0.266
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.264
Human
positive regulation of cell matrix adhesion GO:0001954 1 0.263
cellular nitrogen compound biosynthetic process GO:0044271 218 0.257
Human
biosynthetic process GO:0009058 294 0.256
Human
response to abiotic stimulus GO:0009628 122 0.255
regulation of cell development GO:0060284 100 0.255
Human
single organism organelle organization GO:1902589 199 0.254
wnt signaling pathway GO:0016055 80 0.246
nitrogen compound metabolic process GO:0006807 319 0.245
Human Yeast
positive regulation of cellular metabolic process GO:0031325 94 0.245
meiotic nuclear division GO:0007126 4 0.244
embryonic organ development GO:0048568 381 0.243
hepaticobiliary system development GO:0061008 98 0.240
neuron projection development GO:0031175 180 0.240
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.235
cellular biosynthetic process GO:0044249 286 0.234
Human
regulation of gene expression GO:0010468 265 0.228
Human Yeast
regulation of molecular function GO:0065009 70 0.226
Human
digestive tract morphogenesis GO:0048546 231 0.223
taxis GO:0042330 109 0.222
mitotic cell cycle process GO:1903047 48 0.221
cell migration GO:0016477 237 0.221
regulation of signal transduction GO:0009966 225 0.210
digestive tract development GO:0048565 265 0.209
blood vessel morphogenesis GO:0048514 216 0.206
Zebrafish
epithelial cell morphogenesis GO:0003382 2 0.201
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.197
glial cell development GO:0021782 20 0.196
phosphate containing compound metabolic process GO:0006796 108 0.196
Human Yeast Mouse Worm
single organism localization GO:1902578 225 0.192
cellular aromatic compound metabolic process GO:0006725 295 0.191
Human Yeast
regulation of response to stimulus GO:0048583 269 0.188
regulation of cell migration GO:0030334 40 0.188
Zebrafish
cellular protein metabolic process GO:0044267 129 0.187
Human Yeast Mouse Worm
sensory organ development GO:0007423 393 0.185
organelle organization GO:0006996 227 0.182
cell surface receptor signaling pathway GO:0007166 325 0.179
regulation of eye photoreceptor cell development GO:0042478 2 0.177
establishment or maintenance of apical basal cell polarity GO:0035088 12 0.176
response to fluid shear stress GO:0034405 2 0.174
endodermal cell fate determination GO:0007493 2 0.171
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.171
cellular component disassembly GO:0022411 1 0.169
transport GO:0006810 220 0.167
Zebrafish Mouse Worm
gastrulation GO:0007369 208 0.167
cell substrate adhesion GO:0031589 4 0.165
septum transversum development GO:0003343 4 0.161
liver development GO:0001889 96 0.161
response to chemical GO:0042221 320 0.160
Mouse
embryonic organ morphogenesis GO:0048562 274 0.159
reproduction GO:0000003 40 0.158
Worm
response to external stimulus GO:0009605 264 0.156
regulation of multicellular organismal development GO:2000026 223 0.155
Human Zebrafish Worm
cell migration involved in gastrulation GO:0042074 79 0.155
protein modification process GO:0036211 100 0.154
Human Yeast Mouse Worm
regulation of oligodendrocyte differentiation GO:0048713 1 0.153
cell growth GO:0016049 57 0.153
cell recognition GO:0008037 19 0.152
cellular protein modification process GO:0006464 100 0.152
Human Yeast Mouse Worm
regulation of rna biosynthetic process GO:2001141 213 0.151
Human
maintenance of cell polarity GO:0030011 5 0.150
aging GO:0007568 2 0.150
nucleic acid templated transcription GO:0097659 181 0.150
Human
regulation of biosynthetic process GO:0009889 250 0.150
Human
retinal ganglion cell axon guidance GO:0031290 35 0.149
head development GO:0060322 303 0.148
anterior posterior pattern specification GO:0009952 152 0.148
regulation of neuron projection development GO:0010975 40 0.146
Human
nucleic acid metabolic process GO:0090304 244 0.145
Human Yeast
brain development GO:0007420 293 0.144
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.143
negative regulation of cellular process GO:0048523 283 0.143
Human Zebrafish
regulation of myotube differentiation GO:0010830 2 0.142
regulation of intracellular signal transduction GO:1902531 57 0.139
posttranscriptional gene silencing GO:0016441 3 0.136
protein metabolic process GO:0019538 183 0.135
Human Yeast Mouse Worm
cellular response to endogenous stimulus GO:0071495 68 0.130
Mouse
cellular component biogenesis GO:0044085 178 0.130
Yeast
cilium organization GO:0044782 71 0.126
regulation of metabolic process GO:0019222 359 0.124
Human Yeast
specification of axis polarity GO:0065001 4 0.120
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.120
determination of heart left right asymmetry GO:0061371 117 0.119
notch signaling pathway GO:0007219 35 0.119
stem cell proliferation GO:0072089 4 0.119
regulation of signaling GO:0023051 235 0.116
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.116
establishment of epithelial cell apical basal polarity GO:0045198 2 0.114
mitotic cell cycle GO:0000278 64 0.112
macromolecular complex subunit organization GO:0043933 74 0.112
Yeast Mouse
gland development GO:0048732 143 0.112
pigmentation GO:0043473 85 0.111
cellular localization GO:0051641 97 0.110
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.110
regulation of localization GO:0032879 104 0.109
Zebrafish Mouse
retina morphogenesis in camera type eye GO:0060042 79 0.109
positive regulation of signal transduction GO:0009967 56 0.109
blood vessel development GO:0001568 246 0.108
Zebrafish
venous blood vessel morphogenesis GO:0048845 3 0.108
regulation of locomotion GO:0040012 55 0.108
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.108
Human Yeast Mouse Worm
regulation of multicellular organismal process GO:0051239 277 0.108
Human Zebrafish Worm
developmental growth GO:0048589 166 0.108
muscle cell differentiation GO:0042692 139 0.107
stem cell division GO:0017145 1 0.106
meiotic spindle organization GO:0000212 1 0.105
neuroblast proliferation GO:0007405 2 0.105
regulation of catalytic activity GO:0050790 55 0.102
axon development GO:0061564 166 0.101
modification dependent protein catabolic process GO:0019941 3 0.100
macromolecule biosynthetic process GO:0009059 227 0.099
Human
regulation of neural precursor cell proliferation GO:2000177 3 0.098
striated muscle tissue development GO:0014706 110 0.098
endodermal digestive tract morphogenesis GO:0061031 2 0.098
proteasomal protein catabolic process GO:0010498 2 0.098
axon extension GO:0048675 45 0.097
homeostatic process GO:0042592 142 0.095
meiosis i GO:0007127 1 0.093
mitotic cell cycle embryonic GO:0045448 2 0.092
immune system process GO:0002376 241 0.090
Zebrafish
positive regulation of cell adhesion GO:0045785 1 0.090
response to organic substance GO:0010033 153 0.090
Mouse
regulation of wnt signaling pathway GO:0030111 53 0.090
morphogenesis of an epithelial sheet GO:0002011 49 0.090
heterocycle biosynthetic process GO:0018130 215 0.089
Human
cellular component assembly GO:0022607 170 0.089
Yeast
protein complex subunit organization GO:0071822 46 0.089
Yeast Mouse
digestive system development GO:0055123 289 0.088
cell adhesion GO:0007155 40 0.088
transcription dna templated GO:0006351 181 0.087
Human
primary neural tube formation GO:0014020 1 0.085
regulation of photoreceptor cell differentiation GO:0046532 2 0.085
phagocytosis GO:0006909 3 0.084
positive regulation of cellular component biogenesis GO:0044089 3 0.083
regulation of axonogenesis GO:0050770 32 0.083
eye morphogenesis GO:0048592 144 0.083
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.082
spindle assembly GO:0051225 2 0.082
programmed cell death GO:0012501 119 0.081
Human Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.081
Human
positive regulation of cell substrate adhesion GO:0010811 1 0.081
segmentation GO:0035282 97 0.079
nucleobase containing compound biosynthetic process GO:0034654 205 0.078
Human
positive regulation of cellular catabolic process GO:0031331 3 0.076
regulation of neurogenesis GO:0050767 87 0.076
Human
epithelial tube morphogenesis GO:0060562 148 0.076
biological adhesion GO:0022610 40 0.076
cell cycle GO:0007049 93 0.075
mesenchyme development GO:0060485 127 0.075
regulation of phosphorus metabolic process GO:0051174 43 0.074
cardiac atrium development GO:0003230 4 0.074
dorsal ventral pattern formation GO:0009953 125 0.073
regulation of transcription dna templated GO:0006355 213 0.072
Human
aromatic compound biosynthetic process GO:0019438 217 0.072
Human
epiboly GO:0090504 41 0.071
formation of primary germ layer GO:0001704 62 0.070
positive regulation of transport GO:0051050 2 0.070
Zebrafish Mouse
neuron projection extension GO:1990138 45 0.068
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.068
nuclear transport GO:0051169 4 0.067
neural tube formation GO:0001841 16 0.067
regulation of cell shape GO:0008360 1 0.066
hindbrain development GO:0030902 91 0.066
polarized epithelial cell differentiation GO:0030859 4 0.065
regulation of canonical wnt signaling pathway GO:0060828 34 0.065
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.065
muscle structure development GO:0061061 196 0.065
transcription from rna polymerase ii promoter GO:0006366 80 0.064
single organism cell adhesion GO:0098602 29 0.064
nucleocytoplasmic transport GO:0006913 4 0.064
microtubule based process GO:0007017 60 0.064
skin development GO:0043588 54 0.064
positive regulation of neural precursor cell proliferation GO:2000179 1 0.063
negative regulation of biological process GO:0048519 304 0.063
Human Zebrafish Worm
single organism metabolic process GO:0044710 217 0.063
Yeast
positive regulation of signaling GO:0023056 56 0.062
regulation of epithelial to mesenchymal transition GO:0010717 3 0.062
regulation of programmed cell death GO:0043067 101 0.061
Human Zebrafish
regulation of cell projection organization GO:0031344 44 0.061
Human
regulation of cell communication GO:0010646 232 0.061
axis elongation involved in somitogenesis GO:0090245 2 0.061
response to light stimulus GO:0009416 46 0.060
regulation of stem cell proliferation GO:0072091 2 0.060
neuron migration GO:0001764 22 0.059
negative regulation of cell motility GO:2000146 17 0.059
organic cyclic compound metabolic process GO:1901360 301 0.059
Human Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.059
regulation of organ morphogenesis GO:2000027 35 0.058
organic substance catabolic process GO:1901575 28 0.058
Yeast
regulation of epithelial cell proliferation GO:0050678 3 0.057
cellular protein catabolic process GO:0044257 4 0.057
aorta development GO:0035904 4 0.057
negative regulation of transcription dna templated GO:0045892 45 0.056
forebrain development GO:0030900 96 0.056
tissue regeneration GO:0042246 74 0.056
actomyosin structure organization GO:0031032 53 0.056
female gamete generation GO:0007292 14 0.056
regulation of cell motility GO:2000145 46 0.056
Zebrafish
neuron projection guidance GO:0097485 86 0.055
negative regulation of epithelial cell migration GO:0010633 1 0.055
stem cell fate commitment GO:0048865 1 0.055
left right pattern formation GO:0060972 19 0.054
cell death in response to oxidative stress GO:0036473 2 0.054
endocytosis GO:0006897 16 0.054
Worm
embryonic epithelial tube formation GO:0001838 17 0.053
negative regulation of cellular component movement GO:0051271 18 0.053
stem cell differentiation GO:0048863 117 0.053
germ cell development GO:0007281 22 0.052
defense response to fungus GO:0050832 2 0.052
adherens junction organization GO:0034332 4 0.052
establishment of apical basal cell polarity GO:0035089 2 0.052
Mouse
photoreceptor cell differentiation GO:0046530 55 0.052
Mouse
macromolecule localization GO:0033036 54 0.052
Mouse Worm
growth GO:0040007 174 0.052
regulation of phosphorylation GO:0042325 26 0.052
meiotic cell cycle process GO:1903046 3 0.052
mesenchymal cell development GO:0014031 78 0.051
neural nucleus development GO:0048857 15 0.051
ectoderm development GO:0007398 9 0.050
determination of left right asymmetry in nervous system GO:0035545 4 0.050
negative regulation of cell migration GO:0030336 17 0.049
positive regulation of metabolic process GO:0009893 108 0.049
negative regulation of gene expression GO:0010629 65 0.049
nephron epithelium morphogenesis GO:0072088 1 0.049
negative regulation of signaling GO:0023057 96 0.048
response to growth factor GO:0070848 39 0.048
pronuclear migration GO:0035046 1 0.048
regulation of cellular response to growth factor stimulus GO:0090287 35 0.048
central nervous system formation GO:0021556 1 0.048
negative regulation of signal transduction GO:0009968 94 0.048
posttranscriptional regulation of gene expression GO:0010608 14 0.048
cellular ketone metabolic process GO:0042180 11 0.047
regulation of primary metabolic process GO:0080090 311 0.047
Human Yeast
inner ear development GO:0048839 126 0.047
positive regulation of cell cycle GO:0045787 3 0.047
endothelial cell development GO:0001885 12 0.046
system process GO:0003008 185 0.045
macromolecule modification GO:0043412 111 0.045
Human Yeast Mouse Worm
regulation of cysteine type endopeptidase activity GO:2000116 21 0.045
cellular response to chemical stimulus GO:0070887 157 0.045
Mouse
neurological system process GO:0050877 62 0.045
cell death GO:0008219 121 0.044
Human Zebrafish
negative regulation of epithelial cell proliferation GO:0050680 1 0.044
regulation of cellular component size GO:0032535 30 0.044
mitotic dna integrity checkpoint GO:0044774 4 0.044
intestinal epithelial cell differentiation GO:0060575 3 0.044
oogenesis GO:0048477 14 0.044
positive regulation of cell communication GO:0010647 56 0.043
endoderm development GO:0007492 49 0.043
positive regulation of neurogenesis GO:0050769 24 0.043
Human
homeostasis of number of cells within a tissue GO:0048873 4 0.043
cytokinesis GO:0000910 3 0.043
negative regulation of cell communication GO:0010648 96 0.043
posterior lateral line development GO:0048916 38 0.043
convergent extension GO:0060026 118 0.043
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.043
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.043
morphogenesis of follicular epithelium GO:0016333 1 0.043
regulation of multicellular organism growth GO:0040014 4 0.042
regulation of phosphate metabolic process GO:0019220 43 0.042
pronephros development GO:0048793 69 0.042
cellular amine metabolic process GO:0044106 2 0.042
positive regulation of catabolic process GO:0009896 4 0.042
amine metabolic process GO:0009308 2 0.042
determination of left right asymmetry in diencephalon GO:0035462 4 0.041
positive regulation of response to stimulus GO:0048584 80 0.041
fertilization GO:0009566 3 0.041
positive regulation of developmental process GO:0051094 50 0.041
Human
regulation of anatomical structure size GO:0090066 33 0.041
negative regulation of locomotion GO:0040013 18 0.041
peripheral nervous system development GO:0007422 55 0.041
regulation of cellular amine metabolic process GO:0033238 0 0.041
death GO:0016265 121 0.041
Human Zebrafish
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
foregut morphogenesis GO:0007440 4 0.040
intracellular signal transduction GO:0035556 85 0.040
Yeast
nerve development GO:0021675 45 0.040
spinal cord dorsal ventral patterning GO:0021513 5 0.040
endocardial cushion development GO:0003197 6 0.039
regulation of erk1 and erk2 cascade GO:0070372 4 0.039
chromosome segregation GO:0007059 12 0.039
positive regulation of transcription dna templated GO:0045893 57 0.039
regulation of protein binding GO:0043393 3 0.038
muscle cell development GO:0055001 115 0.038
anterior posterior axis specification GO:0009948 20 0.038
response to uv GO:0009411 3 0.038
regulation of protein catabolic process GO:0042176 1 0.037
cellular response to growth factor stimulus GO:0071363 39 0.037
stem cell maintenance GO:0019827 4 0.037
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.037
regulation of tube size GO:0035150 2 0.037
negative regulation of neural precursor cell proliferation GO:2000178 1 0.036
determination of bilateral symmetry GO:0009855 204 0.036
cell aging GO:0007569 2 0.036
positive regulation of cell development GO:0010720 25 0.036
Human
ventral spinal cord interneuron specification GO:0021521 3 0.036
regulation of dendrite development GO:0050773 3 0.036
regulation of axon extension GO:0030516 24 0.036
negative regulation of macromolecule metabolic process GO:0010605 76 0.036
ras protein signal transduction GO:0007265 7 0.036
regulation of cellular protein metabolic process GO:0032268 52 0.035
rna metabolic process GO:0016070 219 0.035
Human Yeast
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.035
cellular response to organic substance GO:0071310 105 0.035
Mouse
regulation of cell substrate adhesion GO:0010810 1 0.034
phosphorylation GO:0016310 69 0.034
Human Yeast Mouse Worm
desmosome assembly GO:0002159 2 0.034
single fertilization GO:0007338 3 0.034
positive regulation of chromatin modification GO:1903310 1 0.034
response to external biotic stimulus GO:0043207 97 0.034
melanin biosynthetic process GO:0042438 1 0.034
neural tube patterning GO:0021532 33 0.034
extrinsic apoptotic signaling pathway GO:0097191 3 0.034
endocardial cushion formation GO:0003272 2 0.034
hemopoiesis GO:0030097 183 0.034
Zebrafish
intracellular transport GO:0046907 32 0.034
spindle organization GO:0007051 5 0.033
axon guidance GO:0007411 86 0.033
adult behavior GO:0030534 2 0.033
heterocycle metabolic process GO:0046483 290 0.033
Human Yeast
canonical wnt signaling pathway GO:0060070 48 0.033
regulation of gene expression epigenetic GO:0040029 11 0.033
negative regulation of autophagy GO:0010507 1 0.033
regulation of glial cell differentiation GO:0045685 4 0.033
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.032
eye photoreceptor cell development GO:0042462 30 0.032
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.032
axis specification GO:0009798 43 0.032
positive regulation of glial cell differentiation GO:0045687 1 0.032
positive regulation of neuron death GO:1901216 1 0.032
gene silencing by rna GO:0031047 4 0.032
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.032
positive regulation of nervous system development GO:0051962 25 0.032
Human
macromolecular complex assembly GO:0065003 35 0.032
Yeast
embryonic pectoral fin morphogenesis GO:0035118 24 0.032
actin filament organization GO:0007015 15 0.032
Yeast Mouse
striated muscle cell differentiation GO:0051146 129 0.032
regulation of biomineral tissue development GO:0070167 2 0.032
cellular response to external stimulus GO:0071496 2 0.031
regulation of dendrite morphogenesis GO:0048814 3 0.031
convergent extension involved in gastrulation GO:0060027 71 0.031
organic cyclic compound biosynthetic process GO:1901362 223 0.031
Human
regulation of cell adhesion GO:0030155 15 0.031
endocardial cushion morphogenesis GO:0003203 3 0.031
epidermis development GO:0008544 48 0.031
interspecies interaction between organisms GO:0044419 4 0.031
midbrain development GO:0030901 28 0.031
connective tissue development GO:0061448 99 0.031
single organism reproductive process GO:0044702 40 0.030
Worm
cell junction organization GO:0034330 11 0.030
dorsal convergence GO:0060030 14 0.030
regulation of cell size GO:0008361 29 0.030
positive regulation of rna biosynthetic process GO:1902680 57 0.030
lateral line system development GO:0048925 76 0.030
embryonic heart tube left right pattern formation GO:0060971 5 0.030
anatomical structure homeostasis GO:0060249 36 0.030
cellular amino acid metabolic process GO:0006520 7 0.030
regulation of oxidative stress induced cell death GO:1903201 2 0.030
regulation of growth GO:0040008 42 0.030
negative regulation of cell cell adhesion GO:0022408 6 0.029
regulation of cell cell adhesion GO:0022407 13 0.029
erk1 and erk2 cascade GO:0070371 4 0.029
negative regulation of rna biosynthetic process GO:1902679 45 0.029
homeostasis of number of cells GO:0048872 62 0.029
protein complex localization GO:0031503 1 0.029
positive regulation of neuron apoptotic process GO:0043525 1 0.029
spindle assembly involved in meiosis GO:0090306 1 0.028
positive regulation of epithelial cell migration GO:0010634 2 0.028
tissue migration GO:0090130 37 0.028
gastrulation with mouth forming second GO:0001702 44 0.028
cortical actin cytoskeleton organization GO:0030866 1 0.028
neural tube development GO:0021915 62 0.028
protein acylation GO:0043543 3 0.028
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.027
nuclear division GO:0000280 23 0.027
regulation of protein metabolic process GO:0051246 56 0.027
mesoderm formation GO:0001707 43 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.027
cellular response to hypoxia GO:0071456 1 0.027
leukocyte migration GO:0050900 15 0.027
aorta morphogenesis GO:0035909 3 0.026
regulation of purine nucleotide catabolic process GO:0033121 2 0.026
cell migration involved in heart development GO:0060973 22 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
Mouse
embryonic pattern specification GO:0009880 44 0.026
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.026
epithelial to mesenchymal transition GO:0001837 21 0.026
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
somatic stem cell maintenance GO:0035019 1 0.026
microtubule cytoskeleton organization GO:0000226 33 0.026
extracellular structure organization GO:0043062 27 0.026
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.025
organelle fission GO:0048285 23 0.025
cell cell junction organization GO:0045216 10 0.025
regulation of protein transport GO:0051223 3 0.025
hematopoietic or lymphoid organ development GO:0048534 191 0.025
Zebrafish
regulation of vesicle mediated transport GO:0060627 9 0.025
keratinocyte differentiation GO:0030216 0 0.025
cell matrix adhesion GO:0007160 4 0.025
reciprocal meiotic recombination GO:0007131 1 0.025
regulation of cell death GO:0010941 103 0.025
Human Zebrafish
regulation of mitotic cell cycle GO:0007346 25 0.025
pigment cell development GO:0070285 3 0.025
mitotic nuclear division GO:0007067 18 0.025
positive regulation of gliogenesis GO:0014015 2 0.025
Human
neural crest cell migration GO:0001755 42 0.024
regulation of chromatin organization GO:1902275 5 0.024
adherens junction maintenance GO:0034334 2 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
cell substrate junction assembly GO:0007044 2 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024

prkci disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.088
disease of cellular proliferation DOID:14566 0 0.088
organ system cancer DOID:0050686 0 0.088
thoracic cancer DOID:5093 0 0.077
breast cancer DOID:1612 0 0.060