Danio rerio

76 known processes

prkcz

protein kinase C, zeta

(Aliases: pkcz,si:ch211-150o23.4)

prkcz biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neuron development GO:0048666 262 0.565
Mouse
establishment of localization GO:0051234 244 0.563
neuron projection development GO:0031175 180 0.536
Mouse
single organism transport GO:0044765 206 0.531
Zebrafish Mouse Rat
regulation of multicellular organismal development GO:2000026 223 0.476
positive regulation of biological process GO:0048518 253 0.412
Human Zebrafish Mouse Rat
establishment or maintenance of cell polarity GO:0007163 29 0.343
Zebrafish Rat
protein localization to membrane GO:0072657 9 0.340
Mouse
regulation of synapse organization GO:0050807 3 0.310
cell projection morphogenesis GO:0048858 244 0.309
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.302
Human Yeast Rat
organelle localization GO:0051640 49 0.300
cognition GO:0050890 1 0.290
Rat
establishment of localization in cell GO:0051649 77 0.289
regulation of biological quality GO:0065008 263 0.283
Rat
neuron projection morphogenesis GO:0048812 161 0.281
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.275
Human Rat
regulation of cellular biosynthetic process GO:0031326 245 0.274
Rat
cell morphogenesis GO:0000902 289 0.273
Mouse
larval development GO:0002164 2 0.265
cellular component biogenesis GO:0044085 178 0.262
Human Yeast Rat
positive regulation of cellular process GO:0048522 201 0.262
Human Mouse Rat
cell cycle GO:0007049 93 0.261
Zebrafish
cell projection organization GO:0030030 284 0.256
Mouse
protein localization GO:0008104 40 0.255
Mouse Rat
embryonic pattern specification GO:0009880 44 0.255
regulation of cellular component organization GO:0051128 86 0.237
Human Yeast
regulation of synapse assembly GO:0051963 3 0.233
generation of neurons GO:0048699 385 0.223
rna biosynthetic process GO:0032774 181 0.222
Rat
anterior posterior pattern specification GO:0009952 152 0.212
regulation of metabolic process GO:0019222 359 0.212
Human Yeast Rat
neuron differentiation GO:0030182 353 0.211
Mouse
cellular localization GO:0051641 97 0.209
regulation of signaling GO:0023051 235 0.194
Human Rat
hindbrain development GO:0030902 91 0.189
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.189
Rat
response to stress GO:0006950 263 0.186
macromolecule biosynthetic process GO:0009059 227 0.186
Rat
establishment of organelle localization GO:0051656 45 0.181
regulation of molecular function GO:0065009 70 0.178
Rat
cellular biosynthetic process GO:0044249 286 0.175
Rat
regulation of receptor activity GO:0010469 2 0.172
cellular aromatic compound metabolic process GO:0006725 295 0.172
Yeast Rat
regionalization GO:0003002 274 0.172
single organism behavior GO:0044708 24 0.170
Rat
positive regulation of cell adhesion GO:0045785 1 0.163
Rat
cellular response to organic substance GO:0071310 105 0.162
Human Rat
synaptic vesicle transport GO:0048489 1 0.161
positive regulation of cellular component biogenesis GO:0044089 3 0.156
stem cell proliferation GO:0072089 4 0.156
Zebrafish
neuron projection regeneration GO:0031102 16 0.154
cell morphogenesis involved in differentiation GO:0000904 195 0.153
i kappab kinase nf kappab signaling GO:0007249 4 0.153
nucleic acid metabolic process GO:0090304 244 0.149
Yeast Rat
regulation of multicellular organismal process GO:0051239 277 0.147
regulation of developmental process GO:0050793 247 0.147
cell part morphogenesis GO:0032990 246 0.145
Mouse
regulation of glucose import GO:0046324 1 0.143
Zebrafish Rat
segmentation GO:0035282 97 0.142
cell surface receptor signaling pathway GO:0007166 325 0.141
Human Rat
peripheral nervous system development GO:0007422 55 0.141
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.139
Yeast Rat
eye development GO:0001654 277 0.138
embryo development ending in birth or egg hatching GO:0009792 271 0.138
Zebrafish
developmental growth GO:0048589 166 0.130
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.129
Human Rat
organelle organization GO:0006996 227 0.127
Yeast Zebrafish Mouse Rat
biosynthetic process GO:0009058 294 0.126
Rat
regulation of cellular amino acid metabolic process GO:0006521 0 0.126
transport GO:0006810 220 0.125
Zebrafish Mouse Rat
glucose import GO:0046323 2 0.122
Zebrafish Rat
positive regulation of cell cycle GO:0045787 3 0.122
regulation of glucose transport GO:0010827 1 0.120
Zebrafish Rat
wound healing GO:0042060 90 0.119
axonogenesis GO:0007409 152 0.119
establishment of synaptic vesicle localization GO:0097480 1 0.118
neurotransmitter secretion GO:0007269 2 0.118
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.117
lipid catabolic process GO:0016042 4 0.116
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.115
cellular component assembly GO:0022607 170 0.115
Human Yeast Rat
peptide transport GO:0015833 1 0.114
cell cell junction organization GO:0045216 10 0.113
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.110
locomotion GO:0040011 313 0.109
single organism localization GO:1902578 225 0.108
Zebrafish Mouse Rat
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.108
positive regulation of signal transduction GO:0009967 56 0.105
Human Rat
response to organic substance GO:0010033 153 0.105
Human Rat
cytoskeleton organization GO:0007010 96 0.104
Yeast Zebrafish Mouse Rat
aromatic compound biosynthetic process GO:0019438 217 0.104
Rat
system process GO:0003008 185 0.101
Rat
neuroblast proliferation GO:0007405 2 0.100
Zebrafish
sensory organ development GO:0007423 393 0.099
cellular response to hypoxia GO:0071456 1 0.098
signal transduction GO:0007165 455 0.098
Human Yeast Rat
single organism organelle organization GO:1902589 199 0.097
Yeast Zebrafish Mouse Rat
action potential GO:0001508 19 0.097
peripheral nervous system neuron differentiation GO:0048934 28 0.097
amide transport GO:0042886 12 0.096
peptidyl serine modification GO:0018209 2 0.096
Human Rat
axis specification GO:0009798 43 0.095
peripheral nervous system neuron development GO:0048935 22 0.095
heterocycle biosynthetic process GO:0018130 215 0.092
Rat
regulation of epithelial cell proliferation GO:0050678 3 0.091
neurotransmitter transport GO:0006836 2 0.091
regeneration GO:0031099 91 0.091
gene expression GO:0010467 252 0.089
Yeast Rat
peptidyl serine phosphorylation GO:0018105 1 0.089
Human Rat
central nervous system development GO:0007417 387 0.089
Zebrafish
response to transition metal nanoparticle GO:1990267 28 0.087
synaptic growth at neuromuscular junction GO:0051124 2 0.087
protein localization to nucleus GO:0034504 3 0.086
regulation of cellular ketone metabolic process GO:0010565 7 0.086
organic acid metabolic process GO:0006082 31 0.086
localization of cell GO:0051674 244 0.085
organic cyclic compound metabolic process GO:1901360 301 0.085
Yeast Rat
organic substance biosynthetic process GO:1901576 289 0.085
Rat
ion transmembrane transport GO:0034220 91 0.085
Rat
establishment of cell polarity GO:0030010 18 0.084
Zebrafish Rat
response to abiotic stimulus GO:0009628 122 0.084
cell migration GO:0016477 237 0.083
regulation of carbohydrate metabolic process GO:0006109 4 0.082
cellular component morphogenesis GO:0032989 336 0.081
Mouse
embryonic organ morphogenesis GO:0048562 274 0.081
regulation of response to stimulus GO:0048583 269 0.081
Human Mouse Rat
regulation of membrane potential GO:0042391 23 0.080
Rat
cellular response to oxygen levels GO:0071453 1 0.079
negative regulation of biological process GO:0048519 304 0.079
Human Zebrafish Rat
negative regulation of cellular process GO:0048523 283 0.078
Human Zebrafish Rat
adherens junction maintenance GO:0034334 2 0.078
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.077
Yeast Rat
anterior posterior axis specification GO:0009948 20 0.076
cell fate specification GO:0001708 68 0.076
regulation of reactive oxygen species metabolic process GO:2000377 2 0.075
head development GO:0060322 303 0.075
Zebrafish
mitotic cell cycle GO:0000278 64 0.075
Zebrafish
regulation of gene expression GO:0010468 265 0.075
Yeast Rat
response to alkaloid GO:0043279 2 0.075
oxoacid metabolic process GO:0043436 31 0.074
multi organism process GO:0051704 134 0.074
regulation of localization GO:0032879 104 0.073
nucleic acid templated transcription GO:0097659 181 0.072
Rat
protein localization to plasma membrane GO:0072659 1 0.072
Mouse
nuclear transport GO:0051169 4 0.072
actin filament based movement GO:0030048 1 0.071
regulation of transmembrane transporter activity GO:0022898 2 0.071
transmission of nerve impulse GO:0019226 19 0.069
regulation of cell development GO:0060284 100 0.068
epithelial tube morphogenesis GO:0060562 148 0.068
Zebrafish
exocytosis GO:0006887 1 0.068
morphogenesis of an epithelium GO:0002009 333 0.068
Zebrafish
chordate embryonic development GO:0043009 271 0.068
Zebrafish
protein polymerization GO:0051258 4 0.067
positive regulation of cellular metabolic process GO:0031325 94 0.067
Human Rat
neuron projection guidance GO:0097485 86 0.066
negative regulation of protein phosphorylation GO:0001933 4 0.066
Human
adherens junction organization GO:0034332 4 0.066
Zebrafish
locomotory behavior GO:0007626 34 0.066
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.065
small molecule metabolic process GO:0044281 77 0.065
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.065
cellular component movement GO:0006928 335 0.065
response to wounding GO:0009611 116 0.064
regulation of cellular amine metabolic process GO:0033238 0 0.064
embryonic organ development GO:0048568 381 0.063
Zebrafish
nucleocytoplasmic transport GO:0006913 4 0.063
fin morphogenesis GO:0033334 53 0.063
synaptic vesicle localization GO:0097479 1 0.063
skeletal muscle fiber development GO:0048741 35 0.063
apical junction assembly GO:0043297 1 0.062
positive regulation of transport GO:0051050 2 0.061
Zebrafish Mouse Rat
regulation of nitrogen compound metabolic process GO:0051171 251 0.061
Yeast Rat
transcription dna templated GO:0006351 181 0.061
Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.061
Rat
response to carbohydrate GO:0009743 3 0.061
positive regulation of developmental process GO:0051094 50 0.061
Mouse
regulation of protein metabolic process GO:0051246 56 0.059
Human Rat
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.059
nucleobase containing compound biosynthetic process GO:0034654 205 0.059
Rat
determination of bilateral symmetry GO:0009855 204 0.059
striated muscle tissue development GO:0014706 110 0.059
cell cell signaling GO:0007267 52 0.058
Rat
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.058
regulation of jak stat cascade GO:0046425 3 0.058
positive regulation of cellular amine metabolic process GO:0033240 0 0.058
cell junction maintenance GO:0034331 2 0.058
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.057
peripheral nervous system neuron axonogenesis GO:0048936 13 0.057
regulation of macromolecule biosynthetic process GO:0010556 225 0.057
Rat
behavior GO:0007610 74 0.057
Rat
camera type eye development GO:0043010 222 0.057
regulation of inflammatory response GO:0050727 2 0.056
negative regulation of metabolic process GO:0009892 86 0.056
Human Rat
regulation of synaptic plasticity GO:0048167 1 0.056
Rat
locomotor rhythm GO:0045475 3 0.055
protein import into nucleus GO:0006606 3 0.055
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.055
Rat
muscle cell development GO:0055001 115 0.055
developmental maturation GO:0021700 34 0.055
positive regulation of lipid metabolic process GO:0045834 1 0.054
cell cycle process GO:0022402 53 0.054
Zebrafish
ion transport GO:0006811 114 0.054
Rat
single organismal cell cell adhesion GO:0016337 29 0.054
regulation of cell differentiation GO:0045595 142 0.054
Mouse
ameboidal type cell migration GO:0001667 143 0.054
negative regulation of protein kinase activity GO:0006469 4 0.053
protein import GO:0017038 3 0.053
blood circulation GO:0008015 87 0.053
regulation of cellular metabolic process GO:0031323 320 0.053
Human Yeast Rat
regulation of response to nutrient levels GO:0032107 1 0.052
muscle contraction GO:0006936 18 0.052
regulation of ion transport GO:0043269 22 0.052
positive regulation of signaling GO:0023056 56 0.051
Human Rat
renal system development GO:0072001 94 0.051
regulation of metal ion transport GO:0010959 4 0.051
single organism cellular localization GO:1902580 46 0.051
Zebrafish Mouse Rat
nuclear import GO:0051170 3 0.050
negative regulation of gene expression GO:0010629 65 0.050
carboxylic acid metabolic process GO:0019752 22 0.050
autophagy GO:0006914 4 0.050
Yeast
notch signaling pathway GO:0007219 35 0.049
protein targeting to nucleus GO:0044744 3 0.049
heterocycle metabolic process GO:0046483 290 0.049
Yeast Rat
developmental programmed cell death GO:0010623 4 0.049
vesicle localization GO:0051648 27 0.048
Rat
cell fate commitment GO:0045165 99 0.048
regulation of cytoplasmic transport GO:1903649 4 0.048
muscle tissue development GO:0060537 110 0.048
negative regulation of cellular component organization GO:0051129 16 0.048
Human
regulation of filopodium assembly GO:0051489 2 0.048
embryonic heart tube development GO:0035050 133 0.047
Zebrafish
neural tube development GO:0021915 62 0.047
Zebrafish
regulation of cell cycle GO:0051726 52 0.047
calcium mediated signaling GO:0019722 2 0.047
regulation of dendrite development GO:0050773 3 0.047
regulation of axonogenesis GO:0050770 32 0.047
protein secretion GO:0009306 1 0.047
Mouse
response to chemical GO:0042221 320 0.046
Human Rat
single organism nuclear import GO:1902593 3 0.046
myotube cell development GO:0014904 35 0.046
regulation of establishment of protein localization GO:0070201 4 0.045
Mouse Rat
axon development GO:0061564 166 0.045
regulation of neuron differentiation GO:0045664 56 0.045
cytoplasm organization GO:0007028 4 0.045
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.044
cellular response to decreased oxygen levels GO:0036294 1 0.044
taxis GO:0042330 109 0.043
negative regulation of macromolecule metabolic process GO:0010605 76 0.042
Human
protein complex localization GO:0031503 1 0.042
extrinsic apoptotic signaling pathway GO:0097191 3 0.042
camera type eye morphogenesis GO:0048593 108 0.041
negative regulation of cell differentiation GO:0045596 46 0.041
neuronal action potential GO:0019228 18 0.041
tissue regeneration GO:0042246 74 0.041
eye morphogenesis GO:0048592 144 0.041
regulation of protein complex assembly GO:0043254 3 0.041
Human
regulation of intracellular protein transport GO:0033157 3 0.041
mesoderm development GO:0007498 88 0.041
Zebrafish
digestive system development GO:0055123 289 0.041
Zebrafish
cellular ketone metabolic process GO:0042180 11 0.040
axon guidance GO:0007411 86 0.040
chemotaxis GO:0006935 104 0.039
lateral line system development GO:0048925 76 0.039
establishment of protein localization to organelle GO:0072594 4 0.039
rna metabolic process GO:0016070 219 0.039
Yeast Rat
response to drug GO:0042493 3 0.039
regulation of organelle organization GO:0033043 29 0.039
regulation of catalytic activity GO:0050790 55 0.039
Rat
single organism metabolic process GO:0044710 217 0.039
Human Yeast Rat
nucleobase containing compound metabolic process GO:0006139 274 0.039
Yeast Rat
adult behavior GO:0030534 2 0.038
response to glucocorticoid GO:0051384 1 0.038
neuromuscular synaptic transmission GO:0007274 2 0.038
regulation of growth GO:0040008 42 0.038
establishment of epithelial cell polarity GO:0090162 2 0.037
skeletal system morphogenesis GO:0048705 102 0.037
sensory perception of pain GO:0019233 1 0.037
pole plasm assembly GO:0007315 4 0.037
protein complex subunit organization GO:0071822 46 0.036
Human Yeast Rat
regulation of cell adhesion GO:0030155 15 0.036
Rat
amine metabolic process GO:0009308 2 0.036
developmental pigmentation GO:0048066 48 0.036
regulation of programmed cell death GO:0043067 101 0.036
Zebrafish Rat
positive regulation of multicellular organismal process GO:0051240 52 0.036
Mouse
oocyte anterior posterior axis specification GO:0007314 4 0.035
positive regulation of macromolecule metabolic process GO:0010604 93 0.035
Rat
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.035
regulation of system process GO:0044057 40 0.035
growth GO:0040007 174 0.035
Mouse
biological adhesion GO:0022610 40 0.035
Rat
positive regulation of secretion GO:0051047 1 0.034
Mouse
regulation of neurotransmitter secretion GO:0046928 1 0.034
heart development GO:0007507 313 0.034
Zebrafish
response to amino acid GO:0043200 2 0.034
regulation of neuron projection development GO:0010975 40 0.034
regulation of cell communication GO:0010646 232 0.034
Human Rat
hormone secretion GO:0046879 2 0.034
sensory organ morphogenesis GO:0090596 200 0.033
synapse assembly GO:0007416 9 0.033
compound eye development GO:0048749 2 0.033
metal ion homeostasis GO:0055065 26 0.033
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.033
Zebrafish
cellular component maintenance GO:0043954 3 0.033
Zebrafish
regulation of neurogenesis GO:0050767 87 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.032
Rat
regulation of wnt signaling pathway GO:0030111 53 0.032
negative regulation of mapk cascade GO:0043409 4 0.032
programmed cell death GO:0012501 119 0.032
Zebrafish Rat
cellular protein metabolic process GO:0044267 129 0.032
Human Yeast Mouse Rat
blood vessel development GO:0001568 246 0.032
response to copper ion GO:0046688 13 0.032
neurological system process GO:0050877 62 0.032
Rat
response to nicotine GO:0035094 2 0.032
regulation of hormone secretion GO:0046883 2 0.032
multicellular organismal signaling GO:0035637 22 0.031
alcohol biosynthetic process GO:0046165 2 0.031
establishment or maintenance of apical basal cell polarity GO:0035088 12 0.031
Zebrafish
cell substrate adhesion GO:0031589 4 0.031
Rat
cellular amine metabolic process GO:0044106 2 0.031
regulation of organ morphogenesis GO:2000027 35 0.031
cellular macromolecule biosynthetic process GO:0034645 224 0.031
Rat
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.031
Zebrafish
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.031
Mouse
regulation of cell activation GO:0050865 1 0.031
Mouse
regulation of nervous system development GO:0051960 90 0.031
synaptic vesicle endocytosis GO:0048488 1 0.031
vasculogenesis GO:0001570 41 0.031
stem cell maintenance GO:0019827 4 0.031
regulation of multicellular organism growth GO:0040014 4 0.030
cellular protein modification process GO:0006464 100 0.030
Human Yeast Mouse Rat
nitrogen compound metabolic process GO:0006807 319 0.030
Yeast Rat
regulation of signal transduction GO:0009966 225 0.030
Human Rat
homeostatic process GO:0042592 142 0.030
organic substance transport GO:0071702 58 0.030
Zebrafish Mouse Rat
morphogenesis of embryonic epithelium GO:0016331 30 0.030
Zebrafish
negative regulation of kinase activity GO:0033673 4 0.029
aging GO:0007568 2 0.029
determination of heart left right asymmetry GO:0061371 117 0.029
regulation of cell projection assembly GO:0060491 4 0.029
negative regulation of developmental process GO:0051093 65 0.029
response to monosaccharide GO:0034284 3 0.028
cellular response to nutrient levels GO:0031669 2 0.028
regulation of cellular localization GO:0060341 12 0.028
Mouse
developmental cell growth GO:0048588 52 0.028
Mouse
medulla oblongata development GO:0021550 4 0.028
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.028
Human Yeast Mouse Rat
nuclear migration GO:0007097 3 0.028
regulation of calcium ion transport GO:0051924 2 0.028
multicellular organism growth GO:0035264 4 0.028
defense response GO:0006952 47 0.028
astrocyte differentiation GO:0048708 1 0.027
positive regulation of nervous system development GO:0051962 25 0.027
negative regulation of response to stimulus GO:0048585 104 0.027
Human
regulation of postsynaptic membrane potential GO:0060078 1 0.027
Rat
regulation of cell projection organization GO:0031344 44 0.027
regulation of cytokine production GO:0001817 3 0.027
Mouse
stem cell differentiation GO:0048863 117 0.027
regulation of binding GO:0051098 3 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.027
muscle cell differentiation GO:0042692 139 0.027
specification of symmetry GO:0009799 204 0.027
cortical actin cytoskeleton organization GO:0030866 1 0.027
maintenance of location GO:0051235 4 0.026
determination of left right symmetry GO:0007368 179 0.026
positive regulation of response to stimulus GO:0048584 80 0.026
Human Mouse Rat
cartilage condensation GO:0001502 3 0.026
microtubule based process GO:0007017 60 0.026
Zebrafish Mouse Rat
positive regulation of muscle organ development GO:0048636 1 0.026
regulation of cell cell adhesion GO:0022407 13 0.026
negative regulation of map kinase activity GO:0043407 2 0.026
negative regulation of signaling GO:0023057 96 0.026
Human
response to biotic stimulus GO:0009607 97 0.026
negative regulation of biosynthetic process GO:0009890 55 0.026
negative regulation of cell communication GO:0010648 96 0.026
Human
regulation of neurological system process GO:0031644 2 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.026
mesoderm morphogenesis GO:0048332 51 0.026
Zebrafish
maternal determination of anterior posterior axis embryo GO:0008358 4 0.026
protein metabolic process GO:0019538 183 0.026
Human Yeast Mouse Rat
regulation of primary metabolic process GO:0080090 311 0.026
Human Yeast Rat
actin polymerization or depolymerization GO:0008154 2 0.025
chemical homeostasis GO:0048878 49 0.025
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
sleep GO:0030431 1 0.025
cellular response to chemical stimulus GO:0070887 157 0.025
Human Rat
skeletal system development GO:0001501 181 0.025
regulation of nucleocytoplasmic transport GO:0046822 2 0.025
peptidyl threonine modification GO:0018210 1 0.025
cellular carbohydrate metabolic process GO:0044262 4 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
calcium ion dependent exocytosis GO:0017156 1 0.025
positive regulation of cell division GO:0051781 2 0.025
response to corticosteroid GO:0031960 1 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
negative regulation of cytoplasmic transport GO:1903650 2 0.024
positive regulation of synapse assembly GO:0051965 1 0.024
positive regulation of epithelial cell proliferation GO:0050679 1 0.024
positive regulation of translation GO:0045727 1 0.024
stem cell development GO:0048864 82 0.024
reactive oxygen species biosynthetic process GO:1903409 1 0.024
inner ear development GO:0048839 126 0.024
regulation of protein transport GO:0051223 3 0.024
Mouse Rat
regulation of neurotransmitter transport GO:0051588 1 0.024
regulation of protein import into nucleus GO:0042306 2 0.024
circulatory system process GO:0003013 87 0.024
secondary metabolic process GO:0019748 3 0.024
production of molecular mediator of immune response GO:0002440 2 0.024
Mouse
macromolecule localization GO:0033036 54 0.024
Mouse Rat
cellular response to external stimulus GO:0071496 2 0.024
cellular response to stress GO:0033554 62 0.024
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.023
signal transduction in absence of ligand GO:0038034 1 0.023
embryonic skeletal joint development GO:0072498 3 0.023
heart looping GO:0001947 94 0.023
regulation of cellular ph GO:0030641 1 0.023
adherens junction assembly GO:0034333 1 0.023
developmental growth involved in morphogenesis GO:0060560 86 0.023
Mouse
regulation of transporter activity GO:0032409 2 0.023
response to nutrient GO:0007584 3 0.023
response to external stimulus GO:0009605 264 0.023
glial cell proliferation GO:0014009 4 0.023
myotube differentiation GO:0014902 45 0.023
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.022
negative regulation of rna biosynthetic process GO:1902679 45 0.022
muscle fiber development GO:0048747 52 0.022
synapse organization GO:0050808 21 0.022
regulation of neural precursor cell proliferation GO:2000177 3 0.022
cellular protein catabolic process GO:0044257 4 0.022
regulation of defense response GO:0031347 14 0.022
regulation of apoptotic process GO:0042981 98 0.022
Zebrafish Rat
regulation of stem cell differentiation GO:2000736 4 0.022
nitric oxide biosynthetic process GO:0006809 2 0.022
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.022
embryonic axis specification GO:0000578 12 0.022
positive regulation of cytoskeleton organization GO:0051495 3 0.022
regulation of protein localization to nucleus GO:1900180 2 0.022
glucose homeostasis GO:0042593 1 0.022
tissue remodeling GO:0048771 4 0.022
muscle system process GO:0003012 20 0.021
cell death GO:0008219 121 0.021
Zebrafish Rat
muscle structure development GO:0061061 196 0.021
regulation of lipid catabolic process GO:0050994 2 0.021
centrosome localization GO:0051642 1 0.021
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.021
connective tissue development GO:0061448 99 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
synaptic transmission GO:0007268 35 0.021
Rat
brain development GO:0007420 293 0.021
Zebrafish
establishment of protein localization to plasma membrane GO:0090002 1 0.021
protein modification process GO:0036211 100 0.021
Human Yeast Mouse Rat
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
vasculature development GO:0001944 278 0.020
negative regulation of signal transduction GO:0009968 94 0.020
Human
inflammatory response GO:0006954 8 0.020
visual behavior GO:0007632 10 0.020
digestive tract mesoderm development GO:0007502 1 0.020
Zebrafish
neural nucleus development GO:0048857 15 0.020
Zebrafish
sequestering of metal ion GO:0051238 3 0.020
positive regulation of catabolic process GO:0009896 4 0.020
regulation of transcription dna templated GO:0006355 213 0.020
Rat
digestive tract development GO:0048565 265 0.020
Zebrafish
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
actin filament based process GO:0030029 64 0.020
Yeast Rat
establishment of vesicle localization GO:0051650 24 0.020
Rat
macromolecular complex subunit organization GO:0043933 74 0.020
Human Yeast Rat
cellular response to lipopolysaccharide GO:0071222 3 0.020
regulation of response to extracellular stimulus GO:0032104 1 0.020
cell substrate junction assembly GO:0007044 2 0.019
cell growth GO:0016049 57 0.019
Mouse
gamete generation GO:0007276 33 0.019
positive regulation of glucose transport GO:0010828 1 0.019
Zebrafish Rat
heart morphogenesis GO:0003007 156 0.019
cellular macromolecule localization GO:0070727 21 0.019
Mouse Rat
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
single organism reproductive process GO:0044702 40 0.019
regulation of striated muscle contraction GO:0006942 2 0.019
cellular response to biotic stimulus GO:0071216 3 0.019
negative regulation of muscle cell differentiation GO:0051148 1 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
negative regulation of chemotaxis GO:0050922 4 0.019
regulation of intracellular signal transduction GO:1902531 57 0.019
Human Rat
positive regulation of stem cell proliferation GO:2000648 1 0.019
extracellular matrix assembly GO:0085029 1 0.019
insulin like growth factor receptor signaling pathway GO:0048009 4 0.019
cell projection assembly GO:0030031 64 0.019
muscle organ development GO:0007517 101 0.019
carbohydrate biosynthetic process GO:0016051 1 0.018
gland development GO:0048732 143 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018

prkcz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.354
cardiovascular system disease DOID:1287 0 0.105
nervous system disease DOID:863 0 0.100
musculoskeletal system disease DOID:17 0 0.047
heart disease DOID:114 0 0.035
disease of cellular proliferation DOID:14566 0 0.020