Danio rerio

41 known processes

psen2

presenilin 2

(Aliases: zf-PS2,pre2)

psen2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 353 0.169
Fly
signal transduction GO:0007165 455 0.163
regulation of primary metabolic process GO:0080090 311 0.148
Mouse
response to external stimulus GO:0009605 264 0.116
Worm
organic substance biosynthetic process GO:1901576 289 0.113
Mouse
cellular protein catabolic process GO:0044257 4 0.108
Mouse
cellular component morphogenesis GO:0032989 336 0.089
Fly
blood vessel development GO:0001568 246 0.085
gene expression GO:0010467 252 0.084
Human Mouse
larval development GO:0002164 2 0.081
stem cell proliferation GO:0072089 4 0.079
cell projection organization GO:0030030 284 0.076
Fly
nitrogen compound metabolic process GO:0006807 319 0.076
Zebrafish Mouse
response to chemical GO:0042221 320 0.075
Worm
regulation of cellular metabolic process GO:0031323 320 0.074
Mouse
organelle fusion GO:0048284 3 0.069
cell projection morphogenesis GO:0048858 244 0.068
Fly
generation of neurons GO:0048699 385 0.067
Fly
cell morphogenesis GO:0000902 289 0.067
Fly
vasculature development GO:0001944 278 0.065
Zebrafish
cellular protein metabolic process GO:0044267 129 0.064
Mouse Fly
cognition GO:0050890 1 0.063
Mouse
positive regulation of cellular process GO:0048522 201 0.062
Mouse Worm
gtp metabolic process GO:0046039 4 0.062
cellular macromolecule metabolic process GO:0044260 391 0.062
Mouse Fly
lipid storage GO:0019915 1 0.061
organic cyclic compound metabolic process GO:1901360 301 0.059
Mouse
regulation of cell shape GO:0008360 1 0.059
chordate embryonic development GO:0043009 271 0.059
Mouse
blood vessel morphogenesis GO:0048514 216 0.059
regulation of signal transduction GO:0009966 225 0.058
Mouse Worm Fly
developmental growth GO:0048589 166 0.057
single organism membrane fusion GO:0044801 2 0.056
positive regulation of cell cycle GO:0045787 3 0.056
aging GO:0007568 2 0.056
morphogenesis of an epithelium GO:0002009 333 0.055
protein metabolic process GO:0019538 183 0.055
Human Zebrafish Mouse Fly
guanosine containing compound catabolic process GO:1901069 2 0.054
cell morphogenesis involved in differentiation GO:0000904 195 0.054
amine metabolic process GO:0009308 2 0.053
regulation of synaptic plasticity GO:0048167 1 0.053
Mouse
establishment of localization GO:0051234 244 0.052
Mouse Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.052
Mouse
rna biosynthetic process GO:0032774 181 0.052
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.050
Mouse
regulation of signaling GO:0023051 235 0.049
Mouse Worm Fly
multicellular organism growth GO:0035264 4 0.048
negative regulation of biological process GO:0048519 304 0.048
Mouse
gtp catabolic process GO:0006184 2 0.047
guanosine containing compound metabolic process GO:1901068 4 0.047
positive regulation of transport GO:0051050 2 0.047
tube morphogenesis GO:0035239 349 0.046
mitochondrion organization GO:0007005 4 0.046
brain development GO:0007420 293 0.046
regulation of macromolecule metabolic process GO:0060255 317 0.046
Mouse
membrane fusion GO:0061025 2 0.046
synaptic growth at neuromuscular junction GO:0051124 2 0.046
maintenance of location GO:0051235 4 0.046
cellular macromolecule biosynthetic process GO:0034645 224 0.045
Mouse
regulation of metal ion transport GO:0010959 4 0.044
regulation of biological quality GO:0065008 263 0.044
Mouse
cytokinesis GO:0000910 3 0.044
regulation of multicellular organism growth GO:0040014 4 0.043
regulation of metabolic process GO:0019222 359 0.043
Human Mouse
regulation of establishment of protein localization GO:0070201 4 0.043
positive regulation of cellular catabolic process GO:0031331 3 0.042
Mouse
positive regulation of catabolic process GO:0009896 4 0.041
Mouse
neuron projection development GO:0031175 180 0.040
Fly
axon development GO:0061564 166 0.040
regulation of cellular amine metabolic process GO:0033238 0 0.039
sensory organ development GO:0007423 393 0.039
cellular amino acid metabolic process GO:0006520 7 0.039
neuron development GO:0048666 262 0.039
Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.038
autophagy GO:0006914 4 0.038
single organism transport GO:0044765 206 0.038
Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.038
Mouse
intracellular signal transduction GO:0035556 85 0.038
single organism localization GO:1902578 225 0.038
Mouse Fly
positive regulation of biological process GO:0048518 253 0.037
Human Mouse Worm
cellular aromatic compound metabolic process GO:0006725 295 0.037
Mouse
protein localization to plasma membrane GO:0072659 1 0.037
modification dependent protein catabolic process GO:0019941 3 0.037
Mouse
digestive tract morphogenesis GO:0048546 231 0.037
response to abiotic stimulus GO:0009628 122 0.037
Worm
regulation of synapse organization GO:0050807 3 0.036
central nervous system development GO:0007417 387 0.036
death GO:0016265 121 0.036
Mouse
growth GO:0040007 174 0.035
regulation of protein transport GO:0051223 3 0.035
cellular biosynthetic process GO:0044249 286 0.035
Mouse
organonitrogen compound metabolic process GO:1901564 74 0.034
Zebrafish Mouse
regulation of synapse assembly GO:0051963 3 0.034
regulation of nucleoside metabolic process GO:0009118 2 0.034
cellular amine metabolic process GO:0044106 2 0.033
apoptotic process GO:0006915 116 0.033
Mouse
carbohydrate derivative metabolic process GO:1901135 61 0.032
immune system development GO:0002520 191 0.031
Mouse
regulation of biosynthetic process GO:0009889 250 0.031
Mouse
cellular component movement GO:0006928 335 0.031
protein secretion GO:0009306 1 0.031
heterocycle metabolic process GO:0046483 290 0.031
Mouse
single organism metabolic process GO:0044710 217 0.031
meiotic nuclear division GO:0007126 4 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.030
Mouse
angiogenesis GO:0001525 158 0.030
negative regulation of protein kinase activity GO:0006469 4 0.030
Mouse
positive regulation of cellular component biogenesis GO:0044089 3 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.029
Mouse
organelle organization GO:0006996 227 0.029
Fly
phagocytosis GO:0006909 3 0.029
small molecule metabolic process GO:0044281 77 0.029
muscle structure development GO:0061061 196 0.028
cellular response to chemical stimulus GO:0070887 157 0.028
Worm
oxoacid metabolic process GO:0043436 31 0.028
regulation of programmed cell death GO:0043067 101 0.028
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.028
Mouse
digestive tract development GO:0048565 265 0.028
biosynthetic process GO:0009058 294 0.028
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
cell part morphogenesis GO:0032990 246 0.028
Fly
cellular response to extracellular stimulus GO:0031668 2 0.028
regulation of transcription dna templated GO:0006355 213 0.028
Mouse
regulation of protein complex assembly GO:0043254 3 0.028
Mouse
macromolecule modification GO:0043412 111 0.027
Mouse
organic acid metabolic process GO:0006082 31 0.027
nucleic acid templated transcription GO:0097659 181 0.027
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.027
Zebrafish Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
Mouse
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.027
Mouse
response to unfolded protein GO:0006986 2 0.027
digestive system development GO:0055123 289 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
cell migration GO:0016477 237 0.027
carboxylic acid metabolic process GO:0019752 22 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
regulation of cytokine production GO:0001817 3 0.026
cellular ketone metabolic process GO:0042180 11 0.026
cellular component biogenesis GO:0044085 178 0.026
Mouse
regulation of cell death GO:0010941 103 0.026
Mouse
rna localization GO:0006403 4 0.026
meiotic cell cycle process GO:1903046 3 0.025
regulation of purine nucleotide catabolic process GO:0033121 2 0.025
negative regulation of kinase activity GO:0033673 4 0.025
Mouse
somite development GO:0061053 96 0.025
neuroblast proliferation GO:0007405 2 0.025
peptidyl serine modification GO:0018209 2 0.025
cytoskeleton dependent cytokinesis GO:0061640 3 0.024
regulation of nucleotide catabolic process GO:0030811 2 0.024
regulation of stem cell proliferation GO:0072091 2 0.024
regulation of binding GO:0051098 3 0.024
Mouse
peptidyl serine phosphorylation GO:0018105 1 0.023
aromatic compound biosynthetic process GO:0019438 217 0.023
Mouse
regulation of intracellular protein transport GO:0033157 3 0.023
response to stress GO:0006950 263 0.023
response to drug GO:0042493 3 0.023
macromolecule biosynthetic process GO:0009059 227 0.023
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.023
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.023
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
nucleic acid metabolic process GO:0090304 244 0.022
Mouse
neurotransmitter secretion GO:0007269 2 0.022
cellular response to organic substance GO:0071310 105 0.022
Worm
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
nuclear transport GO:0051169 4 0.022
muscle cell development GO:0055001 115 0.022
response to organic substance GO:0010033 153 0.022
Worm
camera type eye development GO:0043010 222 0.022
embryonic limb morphogenesis GO:0030326 2 0.022
Mouse
regulation of developmental process GO:0050793 247 0.022
sensory perception of pain GO:0019233 1 0.022
head development GO:0060322 303 0.022
establishment of protein localization to organelle GO:0072594 4 0.021
cellular response to nutrient levels GO:0031669 2 0.021
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.021
Mouse
lateral inhibition GO:0046331 1 0.021
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
Mouse
positive regulation of gtp catabolic process GO:0033126 1 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.021
Mouse
locomotion GO:0040011 313 0.021
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
Mouse
regulation of peptidase activity GO:0052547 23 0.021
cellular carbohydrate metabolic process GO:0044262 4 0.020
positive regulation of nucleotide catabolic process GO:0030813 1 0.020
establishment of protein localization to plasma membrane GO:0090002 1 0.020
cell motility GO:0048870 244 0.020
negative regulation of cellular process GO:0048523 283 0.020
Mouse
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
neurotransmitter transport GO:0006836 2 0.020
determination of left right symmetry GO:0007368 179 0.020
regulation of cell communication GO:0010646 232 0.020
Mouse Worm Fly
cellular protein modification process GO:0006464 100 0.020
Mouse
erk1 and erk2 cascade GO:0070371 4 0.020
positive regulation of gtpase activity GO:0043547 1 0.020
single organism organelle organization GO:1902589 199 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
Mouse
membrane invagination GO:0010324 1 0.019
taxis GO:0042330 109 0.019
programmed cell death GO:0012501 119 0.019
Mouse
glucose homeostasis GO:0042593 1 0.019
regulation of meiotic cell cycle GO:0051445 1 0.019
rna metabolic process GO:0016070 219 0.019
Mouse
regulation of protein catabolic process GO:0042176 1 0.019
Mouse
regulation of organ growth GO:0046620 3 0.019
regulation of apoptotic process GO:0042981 98 0.019
Mouse
regulation of gtp catabolic process GO:0033124 2 0.019
stem cell division GO:0017145 1 0.019
cellular component maintenance GO:0043954 3 0.019
regulation of endopeptidase activity GO:0052548 23 0.019
cell proliferation GO:0008283 80 0.019
small gtpase mediated signal transduction GO:0007264 8 0.019
cellular component assembly GO:0022607 170 0.019
Mouse
negative regulation of apoptotic process GO:0043066 55 0.019
Mouse
hemopoiesis GO:0030097 183 0.019
Mouse
regulation of protein ubiquitination GO:0031396 3 0.019
Mouse
cellular component disassembly GO:0022411 1 0.019
epithelial cell morphogenesis GO:0003382 2 0.019
positive regulation of secretion GO:0051047 1 0.019
positive regulation of protein complex assembly GO:0031334 2 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
actomyosin structure organization GO:0031032 53 0.018
regionalization GO:0003002 274 0.018
Mouse Fly
exocytosis GO:0006887 1 0.018
regulation of circadian rhythm GO:0042752 4 0.018
heart development GO:0007507 313 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
Mouse
phagocytosis engulfment GO:0006911 1 0.018
somitogenesis GO:0001756 87 0.018
Mouse
eye development GO:0001654 277 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
response to oxygen levels GO:0070482 25 0.018
response to alkaloid GO:0043279 2 0.018
primary neural tube formation GO:0014020 1 0.018
cell substrate adhesion GO:0031589 4 0.018
protein acylation GO:0043543 3 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
Mouse
system process GO:0003008 185 0.017
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
Mouse
regulation of protein metabolic process GO:0051246 56 0.017
Mouse
golgi vesicle transport GO:0048193 3 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
embryonic organ development GO:0048568 381 0.017
muscle cell differentiation GO:0042692 139 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
cellular response to external stimulus GO:0071496 2 0.017
lipid catabolic process GO:0016042 4 0.017
transcription dna templated GO:0006351 181 0.017
Mouse
cilium morphogenesis GO:0060271 85 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.016
Mouse
organelle localization GO:0051640 49 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
response to inorganic substance GO:0010035 38 0.016
negative regulation of cytokine production GO:0001818 1 0.016
regulation of reproductive process GO:2000241 4 0.016
cellular response to starvation GO:0009267 1 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
Mouse
regulation of dendrite development GO:0050773 3 0.016
cell death GO:0008219 121 0.016
Mouse
ameboidal type cell migration GO:0001667 143 0.016
carbohydrate homeostasis GO:0033500 1 0.016
protein complex disassembly GO:0043241 1 0.016
neuron projection morphogenesis GO:0048812 161 0.016
Fly
localization of cell GO:0051674 244 0.016
macromolecule localization GO:0033036 54 0.016
Mouse Worm
actin filament based process GO:0030029 64 0.016
negative regulation of synapse assembly GO:0051964 2 0.016
protein polymerization GO:0051258 4 0.016
positive regulation of metabolic process GO:0009893 108 0.016
Human Mouse
retina development in camera type eye GO:0060041 146 0.016
chemotaxis GO:0006935 104 0.015
regulation of proteolysis GO:0030162 24 0.015
Mouse
gastrulation GO:0007369 208 0.015
immune system process GO:0002376 241 0.015
Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.015
organic substance transport GO:0071702 58 0.015
Mouse
positive regulation of signaling GO:0023056 56 0.015
Mouse Worm
axonogenesis GO:0007409 152 0.015
compound eye development GO:0048749 2 0.015
regulation of gtpase activity GO:0043087 2 0.015
positive regulation of cytokine production GO:0001819 2 0.015
regulation of cellular component organization GO:0051128 86 0.015
Mouse
renal system development GO:0072001 94 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
Mouse
regulation of cell development GO:0060284 100 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
regulation of molecular function GO:0065009 70 0.015
Human Mouse
mesenchyme development GO:0060485 127 0.015
regulation of wound healing GO:0061041 2 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
phosphorus metabolic process GO:0006793 109 0.014
Mouse
cellular amide metabolic process GO:0043603 4 0.014
Zebrafish Mouse
stem cell maintenance GO:0019827 4 0.014
striated muscle cell differentiation GO:0051146 129 0.014
adult behavior GO:0030534 2 0.014
developmental programmed cell death GO:0010623 4 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
signal transduction in absence of ligand GO:0038034 1 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
Mouse
actin filament based movement GO:0030048 1 0.014
cellular respiration GO:0045333 3 0.014
carboxylic acid catabolic process GO:0046395 3 0.014
macromolecular complex assembly GO:0065003 35 0.014
Mouse
neurological system process GO:0050877 62 0.014
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.014
Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.014
cortical actin cytoskeleton organization GO:0030866 1 0.014
post embryonic organ development GO:0048569 4 0.014
Worm
cellular response to endogenous stimulus GO:0071495 68 0.014
Worm
interspecies interaction between organisms GO:0044419 4 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
positive regulation of stem cell proliferation GO:2000648 1 0.014
striated muscle cell development GO:0055002 108 0.014
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.014
Mouse
cilium organization GO:0044782 71 0.014
regulation of response to oxidative stress GO:1902882 2 0.014
gland development GO:0048732 143 0.014
Mouse
positive regulation of apoptotic process GO:0043065 29 0.013
Mouse
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
negative regulation of secretion GO:0051048 2 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
ras protein signal transduction GO:0007265 7 0.013
regulation of protein targeting GO:1903533 2 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
positive regulation of wound healing GO:0090303 1 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
negative regulation of catabolic process GO:0009895 3 0.013
Mouse
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
establishment of organelle localization GO:0051656 45 0.013
regulation of autophagy GO:0010506 3 0.013
positive regulation of response to stimulus GO:0048584 80 0.013
Mouse Worm
cell cycle arrest GO:0007050 1 0.013
positive regulation of gene expression GO:0010628 71 0.013
adherens junction organization GO:0034332 4 0.012
transport GO:0006810 220 0.012
Mouse Fly
response to monosaccharide GO:0034284 3 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
negative regulation of rna splicing GO:0033119 1 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
Mouse
organophosphate metabolic process GO:0019637 37 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
cellular response to stress GO:0033554 62 0.012
protein import GO:0017038 3 0.012
homeostatic process GO:0042592 142 0.012
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
hindbrain development GO:0030902 91 0.012
cell growth GO:0016049 57 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
Mouse
eye morphogenesis GO:0048592 144 0.012
protein acetylation GO:0006473 2 0.012
positive regulation of signal transduction GO:0009967 56 0.012
Mouse Worm
positive regulation of cell division GO:0051781 2 0.012
atp catabolic process GO:0006200 4 0.012
regulation of dna replication GO:0006275 3 0.012
regulation of translational initiation GO:0006446 1 0.012
protein localization to nucleus GO:0034504 3 0.012
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.012
Mouse
alpha amino acid metabolic process GO:1901605 3 0.012
regulation of locomotion GO:0040012 55 0.012
chemosensory behavior GO:0007635 1 0.011
hepaticobiliary system development GO:0061008 98 0.011
fatty acid beta oxidation GO:0006635 1 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
neuron apoptotic process GO:0051402 20 0.011
regulation of rna metabolic process GO:0051252 224 0.011
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
Mouse
regulation of response to stimulus GO:0048583 269 0.011
Mouse Worm Fly
regulation of cell projection organization GO:0031344 44 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
liver development GO:0001889 96 0.011
hormone secretion GO:0046879 2 0.011
cellular localization GO:0051641 97 0.011
cell matrix adhesion GO:0007160 4 0.011
establishment of rna localization GO:0051236 3 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
regulation of receptor mediated endocytosis GO:0048259 4 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
cytokinetic process GO:0032506 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
macromolecular complex disassembly GO:0032984 1 0.011
tissue remodeling GO:0048771 4 0.011
anterior posterior pattern specification GO:0009952 152 0.011
Mouse
tube closure GO:0060606 1 0.011
cilium assembly GO:0042384 58 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
regulation of embryonic development GO:0045995 47 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
embryonic heart tube development GO:0035050 133 0.011
cell projection assembly GO:0030031 64 0.011
regulation of hydrolase activity GO:0051336 28 0.011
glucose import GO:0046323 2 0.011
regulation of membrane potential GO:0042391 23 0.011
regulation of filopodium assembly GO:0051489 2 0.011
morphogenesis of embryonic epithelium GO:0016331 30 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
convergent extension GO:0060026 118 0.011
protein homooligomerization GO:0051260 3 0.011
cellular biogenic amine metabolic process GO:0006576 2 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
protein modification process GO:0036211 100 0.011
Mouse
cellular catabolic process GO:0044248 27 0.011
Mouse
cellular response to hormone stimulus GO:0032870 39 0.011
anatomical structure homeostasis GO:0060249 36 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
cell cycle GO:0007049 93 0.011
activation of mapk activity GO:0000187 3 0.011
mrna 3 end processing GO:0031124 2 0.011
secondary metabolic process GO:0019748 3 0.010
negative regulation of catalytic activity GO:0043086 21 0.010
Mouse
cytoskeleton organization GO:0007010 96 0.010
Fly
negative regulation of programmed cell death GO:0043069 58 0.010
Mouse
rna 3 end processing GO:0031123 2 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
Mouse
skeletal system development GO:0001501 181 0.010
negative regulation of protein complex assembly GO:0031333 1 0.010
Mouse
endosomal transport GO:0016197 2 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
positive regulation of notch signaling pathway GO:0045747 3 0.010
Worm
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.010
nephron morphogenesis GO:0072028 2 0.010
regulation of fatty acid metabolic process GO:0019217 1 0.010
regulation of multicellular organismal process GO:0051239 277 0.010
Mouse
peptide metabolic process GO:0006518 1 0.010
Zebrafish Mouse
negative regulation of multi organism process GO:0043901 3 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
Mouse
gastrulation with mouth forming second GO:0001702 44 0.010
response to glucose GO:0009749 3 0.010
regulation of response to cytokine stimulus GO:0060759 3 0.010
regulation of rna biosynthetic process GO:2001141 213 0.010
Mouse
regulation of gene expression GO:0010468 265 0.010
Mouse

psen2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
Human
nervous system disease DOID:863 0 0.029
Human
disease of metabolism DOID:0014667 0 0.027
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.013
inherited metabolic disorder DOID:655 0 0.012
immune system disease DOID:2914 0 0.011