Danio rerio

0 known processes

psmb9a

proteasome (prosome, macropain) subunit, beta type, 9a

(Aliases: zgc:91842,wu:fj22d05,wu:fa66f04,psmb9,lmp2,prosome,macropain)

psmb9a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.118
cellular macromolecule metabolic process GO:0044260 391 0.110
Yeast
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.104
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.083
Yeast
viral process GO:0016032 1 0.082
regulation of macromolecule metabolic process GO:0060255 317 0.081
regulation of cytokine production GO:0001817 3 0.066
response to stress GO:0006950 263 0.064
cellular nitrogen compound metabolic process GO:0034641 290 0.064
positive regulation of cytokine production GO:0001819 2 0.063
rna metabolic process GO:0016070 219 0.063
response to other organism GO:0051707 97 0.062
immune system process GO:0002376 241 0.062
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.062
macromolecule biosynthetic process GO:0009059 227 0.060
proteasomal protein catabolic process GO:0010498 2 0.060
Yeast
regulation of multicellular organismal process GO:0051239 277 0.055
signal transduction GO:0007165 455 0.054
aromatic compound biosynthetic process GO:0019438 217 0.053
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.052
Yeast
nuclear transport GO:0051169 4 0.051
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.050
nitrogen compound metabolic process GO:0006807 319 0.050
response to biotic stimulus GO:0009607 97 0.049
regulation of cellular amino acid metabolic process GO:0006521 0 0.049
immune system development GO:0002520 191 0.049
positive regulation of cell killing GO:0031343 2 0.045
nucleocytoplasmic transport GO:0006913 4 0.045
regulation of response to stimulus GO:0048583 269 0.045
multicellular organism growth GO:0035264 4 0.045
modification dependent macromolecule catabolic process GO:0043632 3 0.045
Yeast
protein metabolic process GO:0019538 183 0.045
Yeast
response to organic substance GO:0010033 153 0.044
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.042
regulation of rna metabolic process GO:0051252 224 0.042
positive regulation of biological process GO:0048518 253 0.041
response to chemical GO:0042221 320 0.041
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.041
regulation of gene expression GO:0010468 265 0.040
biosynthetic process GO:0009058 294 0.040
embryonic organ development GO:0048568 381 0.040
multi organism cellular process GO:0044764 2 0.039
organic substance biosynthetic process GO:1901576 289 0.039
response to external biotic stimulus GO:0043207 97 0.037
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.036
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.036
regulation of cell activation GO:0050865 1 0.036
regulation of cellular amine metabolic process GO:0033238 0 0.035
regulation of signal transduction GO:0009966 225 0.035
synaptic growth at neuromuscular junction GO:0051124 2 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
nucleobase containing compound metabolic process GO:0006139 274 0.035
aging GO:0007568 2 0.035
regulation of primary metabolic process GO:0080090 311 0.035
protein activation cascade GO:0072376 6 0.034
regulation of transcription dna templated GO:0006355 213 0.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.034
regulation of cytoplasmic transport GO:1903649 4 0.033
defense response GO:0006952 47 0.033
hemopoiesis GO:0030097 183 0.033
negative regulation of protein phosphorylation GO:0001933 4 0.033
stem cell proliferation GO:0072089 4 0.033
protein localization to nucleus GO:0034504 3 0.033
organic acid metabolic process GO:0006082 31 0.032
positive regulation of immune effector process GO:0002699 3 0.032
cellular response to stress GO:0033554 62 0.031
cellular amine metabolic process GO:0044106 2 0.031
regulation of nucleocytoplasmic transport GO:0046822 2 0.031
regulation of biosynthetic process GO:0009889 250 0.031
transcription dna templated GO:0006351 181 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.030
i kappab kinase nf kappab signaling GO:0007249 4 0.030
heterocycle metabolic process GO:0046483 290 0.030
cellular response to unfolded protein GO:0034620 2 0.030
heterocycle biosynthetic process GO:0018130 215 0.029
regulation of synapse organization GO:0050807 3 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.029
response to external stimulus GO:0009605 264 0.029
negative regulation of cellular process GO:0048523 283 0.029
positive regulation of stress activated mapk cascade GO:0032874 3 0.029
tissue remodeling GO:0048771 4 0.028
transcription from rna polymerase ii promoter GO:0006366 80 0.028
regulation of multicellular organismal development GO:2000026 223 0.028
establishment of localization GO:0051234 244 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.027
centrosome organization GO:0051297 1 0.026
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.026
positive regulation of transport GO:0051050 2 0.026
sensory system development GO:0048880 76 0.026
interspecies interaction between organisms GO:0044419 4 0.026
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
regulation of synapse assembly GO:0051963 3 0.025
regulation of jak stat cascade GO:0046425 3 0.025
oxoacid metabolic process GO:0043436 31 0.025
hematopoietic or lymphoid organ development GO:0048534 191 0.025
amine metabolic process GO:0009308 2 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
vacuolar transport GO:0007034 2 0.024
secondary metabolic process GO:0019748 3 0.024
regulation of rna biosynthetic process GO:2001141 213 0.024
exocytosis GO:0006887 1 0.023
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
single organism metabolic process GO:0044710 217 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
nucleic acid templated transcription GO:0097659 181 0.023
peptidyl serine modification GO:0018209 2 0.022
regulation of stem cell differentiation GO:2000736 4 0.022
single fertilization GO:0007338 3 0.022
positive regulation of cellular process GO:0048522 201 0.022
immune response GO:0006955 28 0.022
endoplasmic reticulum unfolded protein response GO:0030968 2 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
inner ear development GO:0048839 126 0.022
gtp metabolic process GO:0046039 4 0.022
regulation of stem cell proliferation GO:0072091 2 0.022
muscle cell development GO:0055001 115 0.021
regulation of dendrite development GO:0050773 3 0.021
hormone secretion GO:0046879 2 0.021
regulation of cell differentiation GO:0045595 142 0.021
leukocyte mediated cytotoxicity GO:0001909 1 0.021
regulation of cell killing GO:0031341 2 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
cellular ketone metabolic process GO:0042180 11 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.021
regulation of protein transport GO:0051223 3 0.020
multi organism process GO:0051704 134 0.020
tyrosine phosphorylation of stat protein GO:0007260 1 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
regulation of protein complex assembly GO:0043254 3 0.020
nuclear import GO:0051170 3 0.020
regulation of signaling GO:0023051 235 0.020
endosomal transport GO:0016197 2 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
positive regulation of response to stimulus GO:0048584 80 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
larval development GO:0002164 2 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
developmental programmed cell death GO:0010623 4 0.020
immune effector process GO:0002252 23 0.020
cellular component biogenesis GO:0044085 178 0.020
phagocytosis GO:0006909 3 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
single organism nuclear import GO:1902593 3 0.019
innate immune response GO:0045087 13 0.019
cellular response to chemical stimulus GO:0070887 157 0.018
complement activation GO:0006956 3 0.018
embryonic skeletal system morphogenesis GO:0048704 93 0.018
er nucleus signaling pathway GO:0006984 2 0.018
response to drug GO:0042493 3 0.018
negative regulation of protein localization to nucleus GO:1900181 2 0.018
intracellular signal transduction GO:0035556 85 0.018
protein targeting to nucleus GO:0044744 3 0.018
positive regulation of cell activation GO:0050867 1 0.018
regulation of cell communication GO:0010646 232 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
cell killing GO:0001906 2 0.018
antimicrobial humoral response GO:0019730 2 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
protein import into nucleus GO:0006606 3 0.018
response to topologically incorrect protein GO:0035966 2 0.018
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
peptidyl serine phosphorylation GO:0018105 1 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
glial cell migration GO:0008347 3 0.017
nucleic acid metabolic process GO:0090304 244 0.017
growth GO:0040007 174 0.017
fertilization GO:0009566 3 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
embryonic cranial skeleton morphogenesis GO:0048701 90 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
regulation of biological quality GO:0065008 263 0.017
regulation of reproductive process GO:2000241 4 0.017
microtubule organizing center organization GO:0031023 1 0.016
regulation of mrna processing GO:0050684 3 0.016
embryonic skeletal system development GO:0048706 97 0.016
regulation of protein targeting GO:1903533 2 0.016
cellular protein metabolic process GO:0044267 129 0.016
Yeast
carbohydrate homeostasis GO:0033500 1 0.016
sensory organ development GO:0007423 393 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
response to unfolded protein GO:0006986 2 0.016
stem cell maintenance GO:0019827 4 0.016
positive regulation of leukocyte mediated immunity GO:0002705 1 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
single organism membrane fusion GO:0044801 2 0.016
negative regulation of response to stimulus GO:0048585 104 0.016
membrane fusion GO:0061025 2 0.016
rna biosynthetic process GO:0032774 181 0.016
b cell mediated immunity GO:0019724 3 0.016
adult behavior GO:0030534 2 0.016
regulation of cell death GO:0010941 103 0.016
lipid storage GO:0019915 1 0.015
germ line stem cell maintenance GO:0030718 2 0.015
mitochondrion organization GO:0007005 4 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
centrosome cycle GO:0007098 1 0.015
cellular amide metabolic process GO:0043603 4 0.015
cellular response to topologically incorrect protein GO:0035967 2 0.015
homeostatic process GO:0042592 142 0.015
cognition GO:0050890 1 0.015
immunoglobulin mediated immune response GO:0016064 3 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
regulation of molecular function GO:0065009 70 0.015
cellular biosynthetic process GO:0044249 286 0.015
spindle assembly GO:0051225 2 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
protein acetylation GO:0006473 2 0.015
neurotransmitter secretion GO:0007269 2 0.015
single organism localization GO:1902578 225 0.015
developmental growth GO:0048589 166 0.015
organism emergence from protective structure GO:0071684 4 0.015
regulation of developmental process GO:0050793 247 0.015
negative regulation of biological process GO:0048519 304 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
gene expression GO:0010467 252 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
negative regulation of nuclear division GO:0051784 3 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.014
protein complex localization GO:0031503 1 0.014
glucose homeostasis GO:0042593 1 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
Yeast
atp catabolic process GO:0006200 4 0.014
regulation of leukocyte mediated cytotoxicity GO:0001910 1 0.014
neuromuscular synaptic transmission GO:0007274 2 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
mitochondrial transport GO:0006839 2 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
neurotransmitter transport GO:0006836 2 0.014
protein heterooligomerization GO:0051291 1 0.014
female sex differentiation GO:0046660 4 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
leukocyte differentiation GO:0002521 25 0.014
regulation of leukocyte mediated immunity GO:0002703 1 0.014
protein import GO:0017038 3 0.014
leukocyte proliferation GO:0070661 1 0.014
positive regulation of leukocyte differentiation GO:1902107 1 0.014
dicarboxylic acid transport GO:0006835 1 0.014
regulation of translational initiation GO:0006446 1 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
angiogenesis GO:0001525 158 0.013
positive regulation of cell communication GO:0010647 56 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
chemosensory behavior GO:0007635 1 0.013
regulation of binding GO:0051098 3 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
gtp catabolic process GO:0006184 2 0.013
blood vessel development GO:0001568 246 0.013
locomotion GO:0040011 313 0.013
cellular protein modification process GO:0006464 100 0.013
b cell differentiation GO:0030183 1 0.013
somatic muscle development GO:0007525 4 0.013
regulation of autophagy GO:0010506 3 0.013
phosphorus metabolic process GO:0006793 109 0.013
amino acid transport GO:0006865 2 0.013
leukocyte homeostasis GO:0001776 2 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
regulation of inflammatory response GO:0050727 2 0.013
regulation of localization GO:0032879 104 0.013
regulation of programmed cell death GO:0043067 101 0.013
liver development GO:0001889 96 0.013
lymphocyte proliferation GO:0046651 1 0.013
maintenance of location GO:0051235 4 0.013
negative regulation of secretion GO:0051048 2 0.013
negative regulation of multi organism process GO:0043901 3 0.013
death GO:0016265 121 0.013
response to cadmium ion GO:0046686 14 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
small molecule metabolic process GO:0044281 77 0.013
negative regulation of gene expression GO:0010629 65 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
positive regulation of cell cycle GO:0045787 3 0.013
cell junction maintenance GO:0034331 2 0.012
positive regulation of catabolic process GO:0009896 4 0.012
positive regulation of chromosome organization GO:2001252 1 0.012
response to carbohydrate GO:0009743 3 0.012
regulation of gtpase activity GO:0043087 2 0.012
negative regulation of catabolic process GO:0009895 3 0.012
mononuclear cell proliferation GO:0032943 1 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
translational initiation GO:0006413 3 0.012
cellular component assembly GO:0022607 170 0.012
intestinal absorption GO:0050892 2 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
cellular component disassembly GO:0022411 1 0.012
peptide transport GO:0015833 1 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
protein homooligomerization GO:0051260 3 0.012
ear development GO:0043583 127 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
peptide metabolic process GO:0006518 1 0.012
post embryonic organ development GO:0048569 4 0.012
protein acylation GO:0043543 3 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
striated muscle cell development GO:0055002 108 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
regulation of protein binding GO:0043393 3 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
hatching GO:0035188 4 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
regulation of cell shape GO:0008360 1 0.012
positive regulation of jak stat cascade GO:0046427 2 0.012
negative regulation of metabolic process GO:0009892 86 0.012
gene silencing by rna GO:0031047 4 0.012
cellular localization GO:0051641 97 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
cellular response to organic substance GO:0071310 105 0.012
transport GO:0006810 220 0.012
negative regulation of reproductive process GO:2000242 3 0.011
meiotic nuclear division GO:0007126 4 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
cortical actin cytoskeleton organization GO:0030866 1 0.011
skeletal system morphogenesis GO:0048705 102 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
regulation of wound healing GO:0061041 2 0.011
sensory organ morphogenesis GO:0090596 200 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
neuron projection development GO:0031175 180 0.011
positive regulation of translation GO:0045727 1 0.011
cytokinesis GO:0000910 3 0.011
complement activation classical pathway GO:0006958 3 0.011
regulation of metal ion transport GO:0010959 4 0.011
negative regulation of mitosis GO:0045839 3 0.011
response to organic cyclic compound GO:0014070 51 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
cellular protein catabolic process GO:0044257 4 0.011
Yeast
ameboidal type cell migration GO:0001667 143 0.011
regulation of exocytosis GO:0017157 1 0.011
ovulation cycle GO:0042698 2 0.011
locomotor rhythm GO:0045475 3 0.011
negative regulation of immune response GO:0050777 2 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
hepaticobiliary system development GO:0061008 98 0.011
cellular response to dsrna GO:0071359 1 0.011
golgi vesicle transport GO:0048193 3 0.011
nik nf kappab signaling GO:0038061 1 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
phagocytosis engulfment GO:0006911 1 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
negative regulation of kinase activity GO:0033673 4 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
sensory perception of pain GO:0019233 1 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
cellular respiration GO:0045333 3 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
spermatid development GO:0007286 2 0.010
cellular response to external stimulus GO:0071496 2 0.010
negative regulation of intracellular protein transport GO:0090317 3 0.010
calcium ion dependent exocytosis GO:0017156 1 0.010
cell aging GO:0007569 2 0.010
post embryonic morphogenesis GO:0009886 4 0.010
negative regulation of defense response GO:0031348 2 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
macromolecular complex subunit organization GO:0043933 74 0.010
positive regulation of wound healing GO:0090303 1 0.010
regulation of immune response GO:0050776 14 0.010
response to uv GO:0009411 3 0.010
regulation of histone methylation GO:0031060 3 0.010
response to abiotic stimulus GO:0009628 122 0.010
regulation of immune system process GO:0002682 34 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
cilium organization GO:0044782 71 0.010
cell cycle arrest GO:0007050 1 0.010
stem cell differentiation GO:0048863 117 0.010
autophagy GO:0006914 4 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
cellular response to retinoic acid GO:0071300 1 0.010
positive regulation of chromatin modification GO:1903310 1 0.010

psmb9a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
musculoskeletal system disease DOID:17 0 0.011