Danio rerio

0 known processes

ptbp2

polypyrimidine tract binding protein 2

(Aliases: im:7153495,wu:fa08f05,wu:fc05d10,si:ch211-160l17.2)

ptbp2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
alternative mrna splicing via spliceosome GO:0000380 1 0.250
meiotic nuclear division GO:0007126 4 0.181
regulation of gene expression GO:0010468 265 0.150
Human
larval development GO:0002164 2 0.139
regulation of nitrogen compound metabolic process GO:0051171 251 0.136
Human
cellular macromolecule metabolic process GO:0044260 391 0.118
Human Mouse
rna metabolic process GO:0016070 219 0.112
Human Mouse
sensory organ development GO:0007423 393 0.096
regulation of fatty acid metabolic process GO:0019217 1 0.095
eye development GO:0001654 277 0.093
regulation of mrna processing GO:0050684 3 0.091
neuron development GO:0048666 262 0.091
organelle organization GO:0006996 227 0.090
nucleic acid metabolic process GO:0090304 244 0.087
Human Mouse
regulation of mrna splicing via spliceosome GO:0048024 3 0.087
muscle structure development GO:0061061 196 0.084
positive regulation of cellular biosynthetic process GO:0031328 68 0.083
neuron differentiation GO:0030182 353 0.083
heterocycle biosynthetic process GO:0018130 215 0.082
negative regulation of biological process GO:0048519 304 0.080
Human Zebrafish
aging GO:0007568 2 0.079
retinoic acid receptor signaling pathway GO:0048384 16 0.079
positive regulation of cellular component biogenesis GO:0044089 3 0.077
rna localization GO:0006403 4 0.077
cellular nitrogen compound biosynthetic process GO:0044271 218 0.076
regulation of synapse organization GO:0050807 3 0.074
stem cell maintenance GO:0019827 4 0.072
positive regulation of transport GO:0051050 2 0.068
Zebrafish
mrna metabolic process GO:0016071 20 0.065
Mouse
female gonad development GO:0008585 4 0.064
regulation of synapse assembly GO:0051963 3 0.064
heterocycle metabolic process GO:0046483 290 0.063
Human Mouse
central nervous system development GO:0007417 387 0.063
cellular component biogenesis GO:0044085 178 0.062
Mouse
compound eye development GO:0048749 2 0.062
positive regulation of rna metabolic process GO:0051254 59 0.061
regulation of primary metabolic process GO:0080090 311 0.059
Human
oocyte anterior posterior axis specification GO:0007314 4 0.057
endothelial cell fate commitment GO:0060839 3 0.057
positive regulation of biological process GO:0048518 253 0.056
Zebrafish
regulation of metabolic process GO:0019222 359 0.055
Human
protein acetylation GO:0006473 2 0.054
nucleic acid templated transcription GO:0097659 181 0.052
generation of neurons GO:0048699 385 0.051
organic cyclic compound metabolic process GO:1901360 301 0.051
Human Mouse
single organism organelle organization GO:1902589 199 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.048
developmental growth GO:0048589 166 0.048
positive regulation of rna biosynthetic process GO:1902680 57 0.046
cellular biosynthetic process GO:0044249 286 0.045
protein acylation GO:0043543 3 0.044
cell projection organization GO:0030030 284 0.043
biosynthetic process GO:0009058 294 0.043
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.043
regulation of cytoplasmic transport GO:1903649 4 0.043
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
negative regulation of gene expression GO:0010629 65 0.043
Human
regulation of developmental process GO:0050793 247 0.042
retina development in camera type eye GO:0060041 146 0.042
fertilization GO:0009566 3 0.042
Zebrafish
female sex differentiation GO:0046660 4 0.042
rna processing GO:0006396 25 0.041
Human Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.039
transcription from rna polymerase iii promoter GO:0006383 1 0.039
transcription dna templated GO:0006351 181 0.037
response to stress GO:0006950 263 0.036
nitrogen compound metabolic process GO:0006807 319 0.036
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.036
Human Mouse
regulation of cell activation GO:0050865 1 0.036
Zebrafish
regulation of biological quality GO:0065008 263 0.035
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.034
stem cell differentiation GO:0048863 117 0.033
transcription from rna polymerase ii promoter GO:0006366 80 0.033
cellular component disassembly GO:0022411 1 0.033
gtp catabolic process GO:0006184 2 0.033
macromolecular complex subunit organization GO:0043933 74 0.033
Mouse
pole plasm assembly GO:0007315 4 0.033
cellular macromolecule biosynthetic process GO:0034645 224 0.032
immune system process GO:0002376 241 0.032
development of primary female sexual characteristics GO:0046545 4 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.031
regulation of cellular ketone metabolic process GO:0010565 7 0.031
meiotic cell cycle process GO:1903046 3 0.031
regulation of cellular metabolic process GO:0031323 320 0.030
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
internal protein amino acid acetylation GO:0006475 2 0.030
nucleocytoplasmic transport GO:0006913 4 0.030
cytoplasm organization GO:0007028 4 0.029
protein metabolic process GO:0019538 183 0.029
regulation of gtp catabolic process GO:0033124 2 0.028
positive regulation of gene expression GO:0010628 71 0.027
regulation of nervous system development GO:0051960 90 0.027
regionalization GO:0003002 274 0.026
Zebrafish
regulation of nucleoside metabolic process GO:0009118 2 0.026
growth GO:0040007 174 0.026
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.025
cytokinesis GO:0000910 3 0.025
positive regulation of transcription dna templated GO:0045893 57 0.025
regulation of purine nucleotide catabolic process GO:0033121 2 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.025
negative regulation of metabolic process GO:0009892 86 0.024
Human
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.024
protein localization to plasma membrane GO:0072659 1 0.024
maternal determination of anterior posterior axis embryo GO:0008358 4 0.024
protein polymerization GO:0051258 4 0.024
stem cell division GO:0017145 1 0.023
cellular macromolecular complex assembly GO:0034622 24 0.023
Mouse
internal peptidyl lysine acetylation GO:0018393 2 0.023
rna biosynthetic process GO:0032774 181 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.023
Human
organic substance biosynthetic process GO:1901576 289 0.023
regulation of protein complex assembly GO:0043254 3 0.022
nuclear transport GO:0051169 4 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
single fertilization GO:0007338 3 0.022
Zebrafish
regulation of stem cell differentiation GO:2000736 4 0.022
intracellular mrna localization GO:0008298 1 0.022
regulation of intracellular protein transport GO:0033157 3 0.022
positive regulation of synapse assembly GO:0051965 1 0.022
peptidyl lysine acetylation GO:0018394 2 0.021
somatic muscle development GO:0007525 4 0.021
stem cell development GO:0048864 82 0.021
lipid storage GO:0019915 1 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
limb bud formation GO:0060174 2 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
Human Mouse
regulation of muscle contraction GO:0006937 3 0.020
maintenance of location GO:0051235 4 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
actin polymerization or depolymerization GO:0008154 2 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.020
system process GO:0003008 185 0.019
Zebrafish
small gtpase mediated signal transduction GO:0007264 8 0.019
positive regulation of catabolic process GO:0009896 4 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
response to radiation GO:0009314 51 0.018
gene expression GO:0010467 252 0.018
Human Mouse
energy reserve metabolic process GO:0006112 2 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
negative regulation of synapse assembly GO:0051964 2 0.018
central nervous system neuron differentiation GO:0021953 74 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.018
multicellular organism growth GO:0035264 4 0.017
cellular component morphogenesis GO:0032989 336 0.017
positive regulation of protein polymerization GO:0032273 2 0.017
cell cycle GO:0007049 93 0.017
homeostasis of number of cells within a tissue GO:0048873 4 0.017
microtubule based process GO:0007017 60 0.017
rna stabilization GO:0043489 4 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
Human
dna templated transcription elongation GO:0006354 3 0.017
segmentation GO:0035282 97 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.017
Mouse
carboxylic acid metabolic process GO:0019752 22 0.017
regulation of rho protein signal transduction GO:0035023 2 0.017
regulation of binding GO:0051098 3 0.017
regulation of reproductive process GO:2000241 4 0.016
Zebrafish
regulation of gtpase activity GO:0043087 2 0.016
regulation of circadian rhythm GO:0042752 4 0.016
response to carbohydrate GO:0009743 3 0.016
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.016
cellular component assembly GO:0022607 170 0.016
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.015
regulation of cell differentiation GO:0045595 142 0.015
cellular protein metabolic process GO:0044267 129 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
Human
cytoskeleton organization GO:0007010 96 0.015
negative regulation of rna metabolic process GO:0051253 48 0.015
Human
hemopoiesis GO:0030097 183 0.015
regulation of transcription dna templated GO:0006355 213 0.015
regulation of biosynthetic process GO:0009889 250 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
regulation of protein polymerization GO:0032271 2 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.015
Human Mouse
negative regulation of histone modification GO:0031057 1 0.015
cellular ketone metabolic process GO:0042180 11 0.015
phagocytosis GO:0006909 3 0.015
aromatic compound biosynthetic process GO:0019438 217 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
convergent extension GO:0060026 118 0.014
camera type eye development GO:0043010 222 0.014
axonogenesis GO:0007409 152 0.014
response to chemical GO:0042221 320 0.014
regulation of cytokine production GO:0001817 3 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.014
regulation of protein transport GO:0051223 3 0.014
actin filament polymerization GO:0030041 2 0.014
multi organism process GO:0051704 134 0.014
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.014
Human
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
Human
transport GO:0006810 220 0.014
Zebrafish
digestive system development GO:0055123 289 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
response to hexose GO:0009746 3 0.014
blood vessel development GO:0001568 246 0.014
sequestering of metal ion GO:0051238 3 0.013
adult behavior GO:0030534 2 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
programmed cell death GO:0012501 119 0.013
response to organic substance GO:0010033 153 0.013
response to external stimulus GO:0009605 264 0.013
stem cell proliferation GO:0072089 4 0.013
diterpenoid metabolic process GO:0016101 15 0.013
rna export from nucleus GO:0006405 1 0.013
protein complex disassembly GO:0043241 1 0.013
nucleobase containing compound transport GO:0015931 2 0.013
lymphatic endothelial cell differentiation GO:0060836 1 0.013
entrainment of circadian clock GO:0009649 2 0.013
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.013
cell part morphogenesis GO:0032990 246 0.013
regulation of cell maturation GO:1903429 1 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.013
regulation of dna templated transcription elongation GO:0032784 3 0.013
immune system development GO:0002520 191 0.013
regulation of meiotic cell cycle GO:0051445 1 0.012
convergent extension involved in gastrulation GO:0060027 71 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
neurological system process GO:0050877 62 0.012
rna transport GO:0050658 2 0.012
mrna export from nucleus GO:0006406 1 0.012
response to abiotic stimulus GO:0009628 122 0.012
tube morphogenesis GO:0035239 349 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
nucleic acid transport GO:0050657 2 0.012
heart development GO:0007507 313 0.012
cell projection morphogenesis GO:0048858 244 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
mrna processing GO:0006397 14 0.012
Mouse
epithelial cell differentiation GO:0030855 116 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
regulation of rac protein signal transduction GO:0035020 1 0.012
endothelial cell differentiation GO:0045446 20 0.012
retinoic acid biosynthetic process GO:0002138 6 0.012
regulation of oocyte development GO:0060281 3 0.012
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.012
positive regulation of cellular process GO:0048522 201 0.011
Zebrafish
macromolecular complex disassembly GO:0032984 1 0.011
oxoacid metabolic process GO:0043436 31 0.011
mitochondrion organization GO:0007005 4 0.011
3 utr mediated mrna stabilization GO:0070935 3 0.011
regulation of localization GO:0032879 104 0.011
Zebrafish
response to amino acid GO:0043200 2 0.011
locomotor rhythm GO:0045475 3 0.011
detection of stimulus GO:0051606 29 0.011
ovulation cycle process GO:0022602 2 0.011
embryonic organ development GO:0048568 381 0.011
sister chromatid cohesion GO:0007062 2 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
regulation of dna templated transcription in response to stress GO:0043620 0 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
protein localization to nucleus GO:0034504 3 0.011
photoreceptor cell maintenance GO:0045494 11 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
intracellular estrogen receptor signaling pathway GO:0030520 3 0.011
gtp metabolic process GO:0046039 4 0.011
establishment of rna localization GO:0051236 3 0.011
defense response to fungus GO:0050832 2 0.011
single organism metabolic process GO:0044710 217 0.011
triglyceride homeostasis GO:0070328 2 0.011
cellular component movement GO:0006928 335 0.010
negative regulation of cellular component organization GO:0051129 16 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
post embryonic organ development GO:0048569 4 0.010
negative regulation of cellular process GO:0048523 283 0.010
Human Zebrafish
response to light stimulus GO:0009416 46 0.010
multi organism reproductive process GO:0044703 36 0.010
Zebrafish
determination of left right symmetry GO:0007368 179 0.010
negative regulation of biosynthetic process GO:0009890 55 0.010
rna splicing via transesterification reactions GO:0000375 10 0.010
Mouse

ptbp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
cardiovascular system disease DOID:1287 0 0.021
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.018
sensory system disease DOID:0050155 0 0.010
nervous system disease DOID:863 0 0.010