Danio rerio

89 known processes

ptch2

patched 2

(Aliases: ptc1,ptch1,ptc-1)

ptch2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
segment polarity determination GO:0007367 1 1.000
retinal ganglion cell axon guidance GO:0031290 35 0.998
neuron projection morphogenesis GO:0048812 161 0.996
axon guidance GO:0007411 86 0.995
periodic partitioning GO:0007365 1 0.994
taxis GO:0042330 109 0.991
dorsal ventral neural tube patterning GO:0021904 1 0.988
multicellular organismal homeostasis GO:0048871 29 0.983
axon development GO:0061564 166 0.983
locomotion GO:0040011 313 0.980
post embryonic morphogenesis GO:0009886 4 0.976
Fly
oligodendrocyte cell fate specification GO:0021778 4 0.974
neuron projection development GO:0031175 180 0.968
protein targeting to nucleus GO:0044744 3 0.966
Fly
cell projection morphogenesis GO:0048858 244 0.966
protein import into nucleus GO:0006606 3 0.964
Fly
female gamete generation GO:0007292 14 0.964
Worm Fly
gamete generation GO:0007276 33 0.964
Worm Fly
neuron projection guidance GO:0097485 86 0.961
protein localization to nucleus GO:0034504 3 0.959
Fly
skeletal muscle fiber development GO:0048741 35 0.958
tissue homeostasis GO:0001894 25 0.958
generation of neurons GO:0048699 385 0.952
multicellular organism reproduction GO:0032504 35 0.949
Worm Fly
regulation of protein targeting GO:1903533 2 0.945
Fly
sexual reproduction GO:0019953 36 0.939
Worm Fly
neuron differentiation GO:0030182 353 0.938
chemotaxis GO:0006935 104 0.937
larval development GO:0002164 2 0.935
Worm
central nervous system projection neuron axonogenesis GO:0021952 15 0.930
cell morphogenesis involved in differentiation GO:0000904 195 0.927
neuron development GO:0048666 262 0.919
cell morphogenesis GO:0000902 289 0.910
response to growth factor GO:0070848 39 0.899
regulation of protein localization to nucleus GO:1900180 2 0.888
Fly
bmp signaling pathway involved in heart development GO:0061312 15 0.887
biosynthetic process GO:0009058 294 0.885
regulation of smoothened signaling pathway GO:0008589 18 0.882
multi organism reproductive process GO:0044703 36 0.874
Worm Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.873
cell part morphogenesis GO:0032990 246 0.865
heart looping GO:0001947 94 0.862
multi organism process GO:0051704 134 0.862
Worm Fly
anterior commissure morphogenesis GO:0021960 3 0.860
direct ossification GO:0036072 3 0.856
Zebrafish
cytoskeleton organization GO:0007010 96 0.854
myotube cell development GO:0014904 35 0.854
developmental growth GO:0048589 166 0.852
Worm
regulation of oligodendrocyte differentiation GO:0048713 1 0.848
cellular component morphogenesis GO:0032989 336 0.840
nucleocytoplasmic transport GO:0006913 4 0.838
Fly
positive regulation of striated muscle cell differentiation GO:0051155 1 0.831
regulation of protein import into nucleus GO:0042306 2 0.828
Fly
smoothened signaling pathway GO:0007224 30 0.826
regulation of multicellular organismal development GO:2000026 223 0.824
neural tube patterning GO:0021532 33 0.822
central nervous system neuron axonogenesis GO:0021955 18 0.818
intramembranous ossification GO:0001957 3 0.809
Zebrafish
regulation of establishment of protein localization GO:0070201 4 0.806
Fly
heart jogging GO:0003146 40 0.804
developmental process involved in reproduction GO:0003006 27 0.803
Worm Fly
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.799
cell projection organization GO:0030030 284 0.794
glial cell fate specification GO:0021780 4 0.778
embryonic digestive tract development GO:0048566 4 0.771
embryonic viscerocranium morphogenesis GO:0048703 52 0.771
notochord development GO:0030903 54 0.766
multicellular organismal reproductive process GO:0048609 35 0.765
Worm Fly
proximal distal pattern formation GO:0009954 1 0.761
skeletal system morphogenesis GO:0048705 102 0.760
single organism nuclear import GO:1902593 3 0.756
Fly
anterior posterior axon guidance GO:0033564 5 0.755
organelle organization GO:0006996 227 0.755
regulation of protein transport GO:0051223 3 0.752
Fly
determination of heart left right asymmetry GO:0061371 117 0.747
floor plate morphogenesis GO:0033505 12 0.746
positive regulation of nucleic acid templated transcription GO:1903508 57 0.743
response to organic substance GO:0010033 153 0.734
positive regulation of cell cycle GO:0045787 3 0.733
embryonic organ development GO:0048568 381 0.729
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.726
floor plate formation GO:0021508 12 0.721
camera type eye morphogenesis GO:0048593 108 0.720
Zebrafish
response to inorganic substance GO:0010035 38 0.698
apoptotic process GO:0006915 116 0.698
Fly
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.691
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.687
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.677
intestinal epithelial structure maintenance GO:0060729 7 0.674
embryonic cranial skeleton morphogenesis GO:0048701 90 0.670
myotube differentiation GO:0014902 45 0.662
axonogenesis GO:0007409 152 0.658
caudal fin development GO:0033336 9 0.655
macromolecular complex subunit organization GO:0043933 74 0.654
motor neuron axon guidance GO:0008045 23 0.654
digestive system development GO:0055123 289 0.651
single organism reproductive process GO:0044702 40 0.646
Worm Fly
bmp signaling pathway involved in heart jogging GO:0003303 14 0.642
embryonic skeletal system morphogenesis GO:0048704 93 0.638
vesicle mediated transport GO:0016192 22 0.638
Worm Fly
somitogenesis GO:0001756 87 0.635
immune system development GO:0002520 191 0.631
glial cell migration GO:0008347 3 0.628
positive regulation of muscle cell differentiation GO:0051149 1 0.625
extracellular matrix assembly GO:0085029 1 0.613
cellular response to growth factor stimulus GO:0071363 39 0.604
establishment of protein localization to organelle GO:0072594 4 0.599
Fly
skeletal system development GO:0001501 181 0.592
negative regulation of epithelial cell proliferation GO:0050680 1 0.585
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.576
protein import GO:0017038 3 0.572
Fly
wnt signaling pathway GO:0016055 80 0.569
regulation of developmental growth GO:0048638 38 0.566
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.559
Worm
camera type eye development GO:0043010 222 0.558
positive regulation of leukocyte differentiation GO:1902107 1 0.557
primary neural tube formation GO:0014020 1 0.546
androgen metabolic process GO:0008209 2 0.543
negative regulation of wnt signaling pathway GO:0030178 30 0.542
bmp signaling pathway GO:0030509 52 0.531
leukocyte proliferation GO:0070661 1 0.531
single organism localization GO:1902578 225 0.529
Fly
spinal cord dorsal ventral patterning GO:0021513 5 0.528
transport GO:0006810 220 0.527
Worm Fly
embryonic digestive tract morphogenesis GO:0048557 3 0.526
regulation of multicellular organism growth GO:0040014 4 0.525
Worm
extracellular structure organization GO:0043062 27 0.520
post embryonic development GO:0009791 7 0.517
Worm Fly
lipid storage GO:0019915 1 0.509
Worm
cerebellar cortex development GO:0021695 5 0.508
response to chemical GO:0042221 320 0.498
cellular response to organic substance GO:0071310 105 0.495
cellular response to biotic stimulus GO:0071216 3 0.490
extracellular matrix organization GO:0030198 27 0.481
heart morphogenesis GO:0003007 156 0.479
multicellular organism growth GO:0035264 4 0.475
Worm
programmed cell death GO:0012501 119 0.475
Fly
proteoglycan metabolic process GO:0006029 14 0.474
neural plate development GO:0001840 10 0.466
ameboidal type cell migration GO:0001667 143 0.463
Fly
odontogenesis of dentin containing tooth GO:0042475 1 0.462
blood vessel morphogenesis GO:0048514 216 0.454
striated muscle cell differentiation GO:0051146 129 0.453
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.447
regulation of developmental process GO:0050793 247 0.444
mesodermal cell migration GO:0008078 12 0.443
protein complex subunit organization GO:0071822 46 0.441
response to acid chemical GO:0001101 17 0.438
regionalization GO:0003002 274 0.431
chordate embryonic development GO:0043009 271 0.424
oogenesis GO:0048477 14 0.423
Worm Fly
blood vessel development GO:0001568 246 0.414
nuclear transport GO:0051169 4 0.414
Fly
positive regulation of muscle organ development GO:0048636 1 0.414
appendage development GO:0048736 80 0.410
Fly
patterning of blood vessels GO:0001569 15 0.407
establishment of localization in cell GO:0051649 77 0.407
Fly
stem cell proliferation GO:0072089 4 0.404
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.402
epithelial tube morphogenesis GO:0060562 148 0.398
embryonic neurocranium morphogenesis GO:0048702 15 0.391
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.389
reproductive structure development GO:0048608 5 0.387
Fly
response to external biotic stimulus GO:0043207 97 0.384
mesoderm development GO:0007498 88 0.383
regulation of intracellular protein transport GO:0033157 3 0.379
Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.377
negative regulation of signal transduction GO:0009968 94 0.377
osteoblast differentiation GO:0001649 5 0.374
response to endogenous stimulus GO:0009719 83 0.374
mononuclear cell proliferation GO:0032943 1 0.374
lymphocyte proliferation GO:0046651 1 0.373
cell projection assembly GO:0030031 64 0.369
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.365
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.365
gland morphogenesis GO:0022612 13 0.353
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.352
anatomical structure homeostasis GO:0060249 36 0.352
regulation of epithelial cell proliferation GO:0050678 3 0.348
nuclear import GO:0051170 3 0.345
Fly
transcription dna templated GO:0006351 181 0.342
endodermal digestive tract morphogenesis GO:0061031 2 0.340
hypophysis morphogenesis GO:0048850 5 0.332
fin morphogenesis GO:0033334 53 0.332
appendage morphogenesis GO:0035107 56 0.331
Fly
tube morphogenesis GO:0035239 349 0.331
regulation of biological quality GO:0065008 263 0.329
Worm Fly
mitotic cell cycle GO:0000278 64 0.328
Fly
response to other organism GO:0051707 97 0.325
embryonic heart tube development GO:0035050 133 0.324
spinal cord patterning GO:0021511 6 0.318
transcription from rna polymerase ii promoter GO:0006366 80 0.318
muscle cell fate commitment GO:0042693 9 0.317
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.317
odontogenesis GO:0042476 9 0.311
ventral spinal cord interneuron fate commitment GO:0060579 3 0.309
cell motility GO:0048870 244 0.305
Fly
microtubule based process GO:0007017 60 0.303
regulation of cytoplasmic transport GO:1903649 4 0.298
Fly
signal transduction GO:0007165 455 0.296
embryonic organ morphogenesis GO:0048562 274 0.296
cell migration GO:0016477 237 0.291
Fly
endocrine system development GO:0035270 65 0.290
sensory organ morphogenesis GO:0090596 200 0.288
Zebrafish Fly
embryonic skeletal system development GO:0048706 97 0.287
positive regulation of developmental process GO:0051094 50 0.286
Worm
regulation of stem cell proliferation GO:0072091 2 0.281
positive regulation of rna metabolic process GO:0051254 59 0.280
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.278
regulation of signal transduction GO:0009966 225 0.277
regulation of neural retina development GO:0061074 2 0.275
cellular component biogenesis GO:0044085 178 0.271
endocardium formation GO:0060214 1 0.269
cellular hormone metabolic process GO:0034754 19 0.268
regulation of apoptotic process GO:0042981 98 0.267
Fly
epithelial cell morphogenesis GO:0003382 2 0.263
neuron fate specification GO:0048665 20 0.262
cell cycle GO:0007049 93 0.262
Fly
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.262
muscle cell fate specification GO:0042694 5 0.260
axis specification GO:0009798 43 0.257
digestive tract development GO:0048565 265 0.252
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.251
positive regulation of muscle tissue development GO:1901863 1 0.251
cellular response to organic cyclic compound GO:0071407 38 0.250
vasculature development GO:0001944 278 0.249
positive regulation of gene expression GO:0010628 71 0.249
protein complex assembly GO:0006461 30 0.248
signal transduction downstream of smoothened GO:0007227 1 0.247
midbrain development GO:0030901 28 0.246
homeostatic process GO:0042592 142 0.245
Fly
cerebellum formation GO:0021588 2 0.244
cellular response to chemical stimulus GO:0070887 157 0.242
single organism organelle organization GO:1902589 199 0.239
positive regulation of glial cell differentiation GO:0045687 1 0.239
regulation of cell morphogenesis GO:0022604 42 0.237
muscle fiber development GO:0048747 52 0.237
floor plate development GO:0033504 15 0.235
negative regulation of programmed cell death GO:0043069 58 0.233
positive regulation of skeletal muscle tissue development GO:0048643 1 0.231
cell fate specification involved in pattern specification GO:0060573 3 0.231
positive regulation of smoothened signaling pathway GO:0045880 5 0.230
muscle organ development GO:0007517 101 0.230
regulation of response to oxidative stress GO:1902882 2 0.228
embryonic heart tube morphogenesis GO:0003143 108 0.225
cellular aromatic compound metabolic process GO:0006725 295 0.225
reproduction GO:0000003 40 0.223
Worm Fly
endocardium development GO:0003157 9 0.223
cellular localization GO:0051641 97 0.222
Fly
regulation of biosynthetic process GO:0009889 250 0.221
skeletal muscle tissue development GO:0007519 67 0.219
regulation of heart morphogenesis GO:2000826 17 0.216
cellular component movement GO:0006928 335 0.215
regulation of response to stimulus GO:0048583 269 0.213
endocrine pancreas development GO:0031018 27 0.213
eye development GO:0001654 277 0.212
stem cell differentiation GO:0048863 117 0.211
cellular macromolecule metabolic process GO:0044260 391 0.211
striated muscle cell development GO:0055002 108 0.210
specification of axis polarity GO:0065001 4 0.210
anterior posterior pattern specification GO:0009952 152 0.207
regulation of mesenchymal cell proliferation GO:0010464 1 0.206
ventral spinal cord development GO:0021517 35 0.206
coagulation GO:0050817 13 0.204
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.203
negative regulation of response to stimulus GO:0048585 104 0.203
organ formation GO:0048645 17 0.199
hemopoiesis GO:0030097 183 0.198
ventral spinal cord interneuron specification GO:0021521 3 0.197
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.197
cardiac endothelial cell differentiation GO:0003348 5 0.192
regulation of transcription dna templated GO:0006355 213 0.191
positive regulation of biological process GO:0048518 253 0.191
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.190
response to external stimulus GO:0009605 264 0.189
cellular component assembly involved in morphogenesis GO:0010927 107 0.189
limb bud formation GO:0060174 2 0.188
regulation of striated muscle cell differentiation GO:0051153 6 0.187
aromatic compound biosynthetic process GO:0019438 217 0.187
skeletal muscle organ development GO:0060538 78 0.186
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.186
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.185
positive regulation of multicellular organismal process GO:0051240 52 0.184
Worm
epithelium migration GO:0090132 25 0.184
Fly
vasculogenesis GO:0001570 41 0.183
single organismal cell cell adhesion GO:0016337 29 0.182
wound healing GO:0042060 90 0.181
rna metabolic process GO:0016070 219 0.181
embryonic pattern specification GO:0009880 44 0.178
axon extension GO:0048675 45 0.178
response to oxygen containing compound GO:1901700 55 0.176
response to biotic stimulus GO:0009607 97 0.176
regulation of nucleocytoplasmic transport GO:0046822 2 0.174
Fly
neuron fate commitment GO:0048663 26 0.172
retinal pigment epithelium development GO:0003406 8 0.171
germ cell development GO:0007281 22 0.171
Worm Fly
biological adhesion GO:0022610 40 0.170
heart field specification GO:0003128 1 0.169
epithelial structure maintenance GO:0010669 8 0.166
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.166
maintenance of gastrointestinal epithelium GO:0030277 7 0.164
cell cycle process GO:0022402 53 0.164
cell aggregation GO:0098743 3 0.163
neural plate morphogenesis GO:0001839 7 0.163
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 1 0.162
muscle cell development GO:0055001 115 0.161
regulation of nucleic acid templated transcription GO:1903506 213 0.161
endocardial cushion morphogenesis GO:0003203 3 0.160
positive regulation of transport GO:0051050 2 0.160
positive regulation of metabolic process GO:0009893 108 0.160
digestive tract morphogenesis GO:0048546 231 0.159
regulation of protein catabolic process GO:0042176 1 0.157
cellular biosynthetic process GO:0044249 286 0.154
cellular response to endogenous stimulus GO:0071495 68 0.152
positive regulation of cell activation GO:0050867 1 0.152
organic substance biosynthetic process GO:1901576 289 0.151
single organism cell adhesion GO:0098602 29 0.151
foregut morphogenesis GO:0007440 4 0.151
embryonic camera type eye formation GO:0060900 10 0.150
post embryonic foregut morphogenesis GO:0048618 3 0.147
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.146
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.145
regeneration GO:0031099 91 0.143
endocytosis GO:0006897 16 0.143
Worm Fly
central nervous system neuron differentiation GO:0021953 74 0.142
dendrite guidance GO:0070983 0 0.141
specification of symmetry GO:0009799 204 0.141
localization of cell GO:0051674 244 0.141
Fly
regulation of neurological system process GO:0031644 2 0.141
central nervous system neuron development GO:0021954 29 0.141
negative regulation of molecular function GO:0044092 23 0.141
negative regulation of developmental process GO:0051093 65 0.140
cell death GO:0008219 121 0.139
Fly
neuron recognition GO:0008038 18 0.138
blood coagulation GO:0007596 12 0.138
pituitary gland development GO:0021983 16 0.137
positive regulation of cellular component biogenesis GO:0044089 3 0.136
axial mesoderm formation GO:0048320 4 0.135
nitrogen compound metabolic process GO:0006807 319 0.134
growth GO:0040007 174 0.133
Worm
regulation of multicellular organismal process GO:0051239 277 0.133
hormone metabolic process GO:0042445 19 0.130
tissue migration GO:0090130 37 0.128
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.128
positive regulation of cellular process GO:0048522 201 0.128
negative regulation of cell communication GO:0010648 96 0.127
cellular component assembly GO:0022607 170 0.127
cellular response to lipid GO:0071396 39 0.125
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.125
regulation of anatomical structure morphogenesis GO:0022603 130 0.124
regulation of macromolecule metabolic process GO:0060255 317 0.123
neuron migration GO:0001764 22 0.123
negative regulation of axon guidance GO:1902668 1 0.122
reactive oxygen species metabolic process GO:0072593 6 0.122
reproductive process GO:0022414 40 0.122
Worm Fly
negative regulation of signaling GO:0023057 96 0.122
pharynx development GO:0060465 5 0.121
regulation of myotube differentiation GO:0010830 2 0.117
medial fin morphogenesis GO:0035141 14 0.117
positive regulation of transcription dna templated GO:0045893 57 0.117
chondrocyte development GO:0002063 4 0.116
muscle structure development GO:0061061 196 0.116
positive regulation of cell differentiation GO:0045597 30 0.116
dendrite morphogenesis GO:0048813 5 0.115
cellular nitrogen compound metabolic process GO:0034641 290 0.115
mitotic cell cycle process GO:1903047 48 0.114
aging GO:0007568 2 0.114
regulation of locomotion GO:0040012 55 0.113
Fly
response to lipid GO:0033993 60 0.112
blood vessel endothelial cell migration GO:0043534 18 0.112
embryonic limb morphogenesis GO:0030326 2 0.112
rostrocaudal neural tube patterning GO:0021903 29 0.112
regulation of macromolecule biosynthetic process GO:0010556 225 0.112
optic placode formation involved in camera type eye formation GO:0046619 3 0.111
maintenance of location GO:0051235 4 0.111
Worm
nuclear division GO:0000280 23 0.111
protein modification process GO:0036211 100 0.110
smooth muscle tissue development GO:0048745 1 0.110
hematopoietic or lymphoid organ development GO:0048534 191 0.110
phosphate containing compound metabolic process GO:0006796 108 0.108
gene expression GO:0010467 252 0.108
establishment of localization GO:0051234 244 0.108
Worm Fly
negative regulation of apoptotic process GO:0043066 55 0.107
dendrite development GO:0016358 9 0.107
epithelial cell migration GO:0010631 25 0.107
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.106
protein complex biogenesis GO:0070271 30 0.105
regulation of wnt signaling pathway GO:0030111 53 0.104
regulation of retina development in camera type eye GO:1902866 2 0.103
regulation of cell migration GO:0030334 40 0.102
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.102
behavior GO:0007610 74 0.101
Worm
regulation of endothelial cell proliferation GO:0001936 1 0.100
fin development GO:0033333 77 0.100
mesenchymal cell development GO:0014031 78 0.100
otolith morphogenesis GO:0032474 8 0.099
mucopolysaccharide metabolic process GO:1903510 2 0.099
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.098
regulation of collagen metabolic process GO:0010712 2 0.097
regulation of cell death GO:0010941 103 0.096
Fly
regulation of rna metabolic process GO:0051252 224 0.096
intracellular signal transduction GO:0035556 85 0.096
muscle cell fate determination GO:0007521 1 0.094
hindbrain development GO:0030902 91 0.094
spinal cord motor neuron differentiation GO:0021522 26 0.094
regulation of cellular component organization GO:0051128 86 0.092
embryonic skeletal joint development GO:0072498 3 0.092
response to fibroblast growth factor GO:0071774 22 0.091
axon extension involved in axon guidance GO:0048846 10 0.090
negative regulation of oocyte development GO:0060283 2 0.086
single organism transport GO:0044765 206 0.086
Fly
negative regulation of cellular process GO:0048523 283 0.086
cytoplasmic transport GO:0016482 11 0.086
Fly
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.085
negative regulation of catabolic process GO:0009895 3 0.085
intracellular transport GO:0046907 32 0.084
Fly
response to mercury ion GO:0046689 1 0.084
heart development GO:0007507 313 0.084
negative regulation of biological process GO:0048519 304 0.084
post embryonic organ development GO:0048569 4 0.083
Fly
regulation of axonogenesis GO:0050770 32 0.082
regulation of cellular response to growth factor stimulus GO:0090287 35 0.081
regulation of signaling GO:0023051 235 0.081
positive regulation of rna biosynthetic process GO:1902680 57 0.080
mesenchymal cell proliferation GO:0010463 1 0.080
astrocyte differentiation GO:0048708 1 0.080
developmental growth involved in morphogenesis GO:0060560 86 0.079
endocardial cell differentiation GO:0060956 5 0.079
retinoic acid metabolic process GO:0042573 9 0.077
heterocycle biosynthetic process GO:0018130 215 0.077
determination of dorsal ventral asymmetry GO:0048262 34 0.076
specification of organ identity GO:0010092 2 0.076
positive regulation of cellular biosynthetic process GO:0031328 68 0.076
positive regulation of epithelial cell proliferation GO:0050679 1 0.076
epithelial cell differentiation GO:0030855 116 0.076
positive regulation of striated muscle tissue development GO:0045844 1 0.076
regulation of biomineral tissue development GO:0070167 2 0.075
macromolecular complex assembly GO:0065003 35 0.074
segmentation GO:0035282 97 0.074
regulation of glial cell differentiation GO:0045685 4 0.074
photoreceptor cell fate commitment GO:0046552 1 0.073
regulation of cell communication GO:0010646 232 0.073
regulation of metabolic process GO:0019222 359 0.073
nephron development GO:0072006 31 0.072
small molecule metabolic process GO:0044281 77 0.072
positive regulation of macromolecule metabolic process GO:0010604 93 0.072
collagen metabolic process GO:0032963 2 0.072
neuroblast differentiation GO:0014016 1 0.072
body morphogenesis GO:0010171 16 0.071
regulation of cell differentiation GO:0045595 142 0.071
protein metabolic process GO:0019538 183 0.071
nucleobase containing compound biosynthetic process GO:0034654 205 0.071
cardiac cell fate commitment GO:0060911 1 0.070
somite development GO:0061053 96 0.070
muscle cell differentiation GO:0042692 139 0.070
regulation of cytokine production GO:0001817 3 0.069
cerebellum development GO:0021549 17 0.069
axis elongation GO:0003401 31 0.068
pharyngeal muscle development GO:0043282 4 0.068
regulation of cellular biosynthetic process GO:0031326 245 0.068
rna biosynthetic process GO:0032774 181 0.067
regulation of reproductive process GO:2000241 4 0.066
regulation of cell proliferation involved in tissue homeostasis GO:0060784 2 0.066
cell proliferation in dorsal spinal cord GO:0010456 2 0.066
regulation of cardiac muscle tissue development GO:0055024 1 0.065
regulation of muscle tissue development GO:1901861 6 0.065
pancreas development GO:0031016 84 0.065
diencephalon development GO:0021536 58 0.065
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.065
vestibular receptor cell development GO:0060118 3 0.065
ossification GO:0001503 23 0.064
regulation of programmed cell death GO:0043067 101 0.064
Fly
cell migration in hindbrain GO:0021535 7 0.064
regulation of organ morphogenesis GO:2000027 35 0.063
cellular macromolecule localization GO:0070727 21 0.063
Fly
heart growth GO:0060419 7 0.062
ventral midline development GO:0007418 13 0.062
negative regulation of cell migration GO:0030336 17 0.062
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 1 0.062
3 utr mediated mrna stabilization GO:0070935 3 0.062
isoprenoid metabolic process GO:0006720 15 0.061
dorsal ventral axis specification GO:0009950 14 0.061
cell cell signaling GO:0007267 52 0.060
regulation of striated muscle tissue development GO:0016202 6 0.059
positive regulation of response to stimulus GO:0048584 80 0.059
regulation of reactive oxygen species metabolic process GO:2000377 2 0.059
regulation of growth GO:0040008 42 0.059
Worm
positive regulation of biosynthetic process GO:0009891 68 0.059

ptch2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.674
musculoskeletal system cancer DOID:0060100 0 0.196
cancer DOID:162 0 0.196
disease of cellular proliferation DOID:14566 0 0.196
organ system cancer DOID:0050686 0 0.196
bone development disease DOID:0080006 0 0.150
bone disease DOID:0080001 0 0.150
musculoskeletal system disease DOID:17 0 0.150
connective tissue disease DOID:65 0 0.150
disease of mental health DOID:150 0 0.060
developmental disorder of mental health DOID:0060037 0 0.060