Danio rerio

76 known processes

ptena

phosphatase and tensin homolog A

(Aliases: wu:fc52g04,MGC73086,zgc:73086)

ptena biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular process GO:0048523 283 0.645
Human Mouse Worm Fly
larval development GO:0002164 2 0.627
Worm Fly
negative regulation of biological process GO:0048519 304 0.450
Human Mouse Worm Fly
positive regulation of catabolic process GO:0009896 4 0.449
Human Mouse
response to organic substance GO:0010033 153 0.443
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.420
Human Fly
signal transduction GO:0007165 455 0.409
regulation of macromolecule metabolic process GO:0060255 317 0.398
Human Mouse
regulation of response to stimulus GO:0048583 269 0.389
regulation of metabolic process GO:0019222 359 0.371
Human Mouse Fly
single organism metabolic process GO:0044710 217 0.355
hemopoiesis GO:0030097 183 0.351
organelle organization GO:0006996 227 0.346
Human Mouse Fly
regulation of signal transduction GO:0009966 225 0.339
regulation of establishment of protein localization GO:0070201 4 0.332
Worm
positive regulation of cellular process GO:0048522 201 0.318
Human Mouse
blood vessel morphogenesis GO:0048514 216 0.306
Mouse
response to chemical GO:0042221 320 0.302
Worm Fly
intracellular signal transduction GO:0035556 85 0.288
cell morphogenesis involved in differentiation GO:0000904 195 0.288
Mouse
cell part morphogenesis GO:0032990 246 0.283
Mouse
single organism localization GO:1902578 225 0.275
Mouse Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.272
Human
regulation of gene expression GO:0010468 265 0.272
Human
cellular response to chemical stimulus GO:0070887 157 0.272
Fly
cellular protein metabolic process GO:0044267 129 0.271
Human Mouse Worm Fly
cell projection morphogenesis GO:0048858 244 0.256
Mouse
maintenance of location GO:0051235 4 0.247
Fly
generation of neurons GO:0048699 385 0.245
Mouse Fly
regulation of cellular protein metabolic process GO:0032268 52 0.240
Human Mouse
regulation of multicellular organismal development GO:2000026 223 0.239
Mouse Fly
rna metabolic process GO:0016070 219 0.236
Human
regulation of protein transport GO:0051223 3 0.236
Worm
digestive tract development GO:0048565 265 0.234
Zebrafish
vasculature development GO:0001944 278 0.231
locomotion GO:0040011 313 0.230
Human Mouse Worm
nucleic acid templated transcription GO:0097659 181 0.218
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.212
Human
aging GO:0007568 2 0.212
Mouse Worm
blood vessel development GO:0001568 246 0.209
regulation of macromolecule biosynthetic process GO:0010556 225 0.208
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.206
Human
apoptotic process GO:0006915 116 0.206
Mouse Fly
protein import into nucleus GO:0006606 3 0.204
Worm
regulation of rna biosynthetic process GO:2001141 213 0.198
Human
cellular component movement GO:0006928 335 0.195
Human Mouse
protein localization to nucleus GO:0034504 3 0.194
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.191
Human
positive regulation of biological process GO:0048518 253 0.190
Human Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.189
regulation of signaling GO:0023051 235 0.184
regulation of cell motility GO:2000145 46 0.183
Human
cellular amine metabolic process GO:0044106 2 0.180
single organism organelle organization GO:1902589 199 0.178
Human Mouse Fly
regulation of biosynthetic process GO:0009889 250 0.171
Human
amine metabolic process GO:0009308 2 0.170
transport GO:0006810 220 0.169
Worm
gene expression GO:0010467 252 0.169
Human
multicellular organism growth GO:0035264 4 0.169
Fly
organic substance biosynthetic process GO:1901576 289 0.168
Human
immune system process GO:0002376 241 0.167
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.166
regulation of primary metabolic process GO:0080090 311 0.165
Human Mouse
positive regulation of metabolic process GO:0009893 108 0.163
Human Mouse
positive regulation of map kinase activity GO:0043406 3 0.162
nuclear transport GO:0051169 4 0.162
Worm
phosphate containing compound metabolic process GO:0006796 108 0.162
central nervous system neuron differentiation GO:0021953 74 0.159
Mouse
response to drug GO:0042493 3 0.156
peptidyl serine phosphorylation GO:0018105 1 0.155
regulation of neuron differentiation GO:0045664 56 0.151
Mouse Fly
regulation of neurogenesis GO:0050767 87 0.150
Mouse Fly
cell migration GO:0016477 237 0.149
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.149
Human
establishment of protein localization to organelle GO:0072594 4 0.148
Worm
protein modification process GO:0036211 100 0.148
Human Mouse Worm Fly
response to external stimulus GO:0009605 264 0.146
Mouse Worm Fly
cellular biosynthetic process GO:0044249 286 0.145
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.140
cellular component morphogenesis GO:0032989 336 0.140
Mouse Fly
cell projection organization GO:0030030 284 0.139
Mouse Fly
cellular ketone metabolic process GO:0042180 11 0.139
axonogenesis GO:0007409 152 0.138
Mouse
regulation of protein binding GO:0043393 3 0.138
cellular protein modification process GO:0006464 100 0.136
Human Mouse Worm Fly
chromosome organization GO:0051276 31 0.136
Human Mouse
single organism transport GO:0044765 206 0.135
Worm
neuron projection morphogenesis GO:0048812 161 0.134
Mouse
macromolecule modification GO:0043412 111 0.134
Human Mouse Worm Fly
cellular macromolecule metabolic process GO:0044260 391 0.133
Human Mouse Worm Fly
protein metabolic process GO:0019538 183 0.133
Human Mouse Worm Fly
cell death GO:0008219 121 0.131
Mouse Fly
regulation of cell migration GO:0030334 40 0.128
Human
regulation of wound healing GO:0061041 2 0.127
cellular amino acid metabolic process GO:0006520 7 0.127
regulation of response to stress GO:0080134 36 0.127
Fly
regulation of multicellular organism growth GO:0040014 4 0.124
Fly
regulation of protein metabolic process GO:0051246 56 0.123
Human Mouse
regulation of intracellular signal transduction GO:1902531 57 0.122
developmental process involved in reproduction GO:0003006 27 0.121
Mouse
biosynthetic process GO:0009058 294 0.119
Human
positive regulation of transport GO:0051050 2 0.117
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.117
Mouse
neuron development GO:0048666 262 0.114
Mouse Fly
modification dependent protein catabolic process GO:0019941 3 0.114
Human Mouse
regulation of cell development GO:0060284 100 0.113
Mouse Fly
regulation of phosphorus metabolic process GO:0051174 43 0.112
Human
death GO:0016265 121 0.112
Mouse Fly
response to stress GO:0006950 263 0.111
Mouse Worm Fly
stem cell maintenance GO:0019827 4 0.111
phosphorus metabolic process GO:0006793 109 0.111
regulation of developmental process GO:0050793 247 0.110
Mouse Fly
stem cell proliferation GO:0072089 4 0.109
cellular response to nutrient levels GO:0031669 2 0.109
regulation of transcription dna templated GO:0006355 213 0.106
Human
positive regulation of cell cycle GO:0045787 3 0.106
Human Mouse
regulation of localization GO:0032879 104 0.105
Human Mouse Worm
extrinsic apoptotic signaling pathway GO:0097191 3 0.105
regulation of cellular amino acid metabolic process GO:0006521 0 0.105
activation of mapk activity GO:0000187 3 0.104
regulation of cellular ketone metabolic process GO:0010565 7 0.103
heterocycle biosynthetic process GO:0018130 215 0.102
Human
positive regulation of cellular catabolic process GO:0031331 3 0.102
Human Mouse
cell morphogenesis GO:0000902 289 0.101
Mouse Fly
tube morphogenesis GO:0035239 349 0.101
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.101
Human Fly
digestive system development GO:0055123 289 0.100
Zebrafish
response to endogenous stimulus GO:0009719 83 0.098
Fly
meiotic nuclear division GO:0007126 4 0.098
axon development GO:0061564 166 0.098
Mouse Fly
positive regulation of cell communication GO:0010647 56 0.098
Mouse
positive regulation of signal transduction GO:0009967 56 0.097
Mouse
regulation of cytoplasmic transport GO:1903649 4 0.096
Worm
reproduction GO:0000003 40 0.096
Mouse
angiogenesis GO:0001525 158 0.096
Mouse
neuron projection development GO:0031175 180 0.095
Mouse Fly
response to radiation GO:0009314 51 0.095
phosphorylation GO:0016310 69 0.094
Human
regulation of cell communication GO:0010646 232 0.094
embryonic organ development GO:0048568 381 0.093
homeostatic process GO:0042592 142 0.092
multi organism process GO:0051704 134 0.092
Mouse
autophagy GO:0006914 4 0.091
Fly
negative regulation of multicellular organismal process GO:0051241 69 0.091
Mouse Fly
cellular response to external stimulus GO:0071496 2 0.091
small molecule metabolic process GO:0044281 77 0.090
Human
organelle fission GO:0048285 23 0.089
Human Mouse
macromolecular complex subunit organization GO:0043933 74 0.089
Fly
negative regulation of cellular metabolic process GO:0031324 77 0.089
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.088
Human
regulation of nervous system development GO:0051960 90 0.087
Mouse Fly
regulation of multicellular organismal process GO:0051239 277 0.086
Mouse Fly
head development GO:0060322 303 0.086
Mouse
neuron differentiation GO:0030182 353 0.086
Mouse Fly
cell motility GO:0048870 244 0.085
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.085
positive regulation of secretion by cell GO:1903532 1 0.084
protein import GO:0017038 3 0.083
Worm
muscle organ development GO:0007517 101 0.083
organic acid metabolic process GO:0006082 31 0.083
regulation of apoptotic process GO:0042981 98 0.082
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.080
Human
developmental growth GO:0048589 166 0.080
Mouse Fly
cellular response to extracellular stimulus GO:0031668 2 0.079
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.079
positive regulation of macromolecule metabolic process GO:0010604 93 0.078
Human Mouse
cellular response to organic substance GO:0071310 105 0.077
Fly
positive regulation of response to stimulus GO:0048584 80 0.077
Mouse
reproductive process GO:0022414 40 0.077
Mouse
response to oxygen containing compound GO:1901700 55 0.076
Fly
regulation of intracellular protein transport GO:0033157 3 0.076
Worm
circadian rhythm GO:0007623 19 0.076
Mouse
localization of cell GO:0051674 244 0.075
Human Mouse
heterocycle metabolic process GO:0046483 290 0.074
Human
meiotic chromosome segregation GO:0045132 3 0.074
digestive tract morphogenesis GO:0048546 231 0.074
Zebrafish
regulation of biological quality GO:0065008 263 0.074
Human Mouse Fly
positive regulation of wound healing GO:0090303 1 0.074
establishment of localization GO:0051234 244 0.073
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.073
cellular response to growth factor stimulus GO:0071363 39 0.073
endosomal transport GO:0016197 2 0.073
negative regulation of cell communication GO:0010648 96 0.072
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.072
regulation of catalytic activity GO:0050790 55 0.071
Human Mouse
muscle cell differentiation GO:0042692 139 0.071
response to growth factor GO:0070848 39 0.071
rhythmic process GO:0048511 21 0.070
Mouse
response to wounding GO:0009611 116 0.070
Fly
regulation of locomotion GO:0040012 55 0.070
Human Worm
carboxylic acid metabolic process GO:0019752 22 0.070
mitotic nuclear division GO:0007067 18 0.069
Human Mouse
response to hormone GO:0009725 48 0.069
Fly
positive regulation of immune response GO:0050778 11 0.069
cellular component biogenesis GO:0044085 178 0.069
Human Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.069
Human
regulation of protein localization to nucleus GO:1900180 2 0.068
Worm
stem cell division GO:0017145 1 0.068
regulation of nucleocytoplasmic transport GO:0046822 2 0.067
Worm
myeloid cell differentiation GO:0030099 86 0.067
phagocytosis engulfment GO:0006911 1 0.067
regulation of cell matrix adhesion GO:0001952 1 0.067
Human
oxoacid metabolic process GO:0043436 31 0.066
positive regulation of cellular amine metabolic process GO:0033240 0 0.066
positive regulation of cellular metabolic process GO:0031325 94 0.066
Human Mouse
negative regulation of developmental process GO:0051093 65 0.066
Mouse Fly
protein targeting to nucleus GO:0044744 3 0.066
Worm
positive regulation of cellular protein metabolic process GO:0032270 22 0.065
Human Mouse
nucleocytoplasmic transport GO:0006913 4 0.065
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.065
Human
negative regulation of protein transport GO:0051224 3 0.065
Worm
nuclear import GO:0051170 3 0.065
Worm
cell substrate adhesion GO:0031589 4 0.064
Human
transcription dna templated GO:0006351 181 0.064
Human
system process GO:0003008 185 0.064
Mouse Worm
organic cyclic compound metabolic process GO:1901360 301 0.063
Human Fly
cell adhesion GO:0007155 40 0.063
Human Fly
regulation of cellular extravasation GO:0002691 1 0.063
cellular response to lipopolysaccharide GO:0071222 3 0.062
establishment of localization in cell GO:0051649 77 0.062
Worm
positive regulation of signaling GO:0023056 56 0.062
Mouse
single organism nuclear import GO:1902593 3 0.062
Worm
cytokinesis GO:0000910 3 0.062
regulation of cellular metabolic process GO:0031323 320 0.061
Human Mouse Fly
positive regulation of apoptotic signaling pathway GO:2001235 1 0.060
Mouse
immune system development GO:0002520 191 0.060
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.060
positive regulation of developmental process GO:0051094 50 0.060
cellular nitrogen compound biosynthetic process GO:0044271 218 0.060
Human
oocyte differentiation GO:0009994 14 0.059
regulation of rna metabolic process GO:0051252 224 0.059
Human
negative regulation of protein kinase activity GO:0006469 4 0.059
Human
regulation of transport GO:0051049 45 0.059
Worm
organonitrogen compound metabolic process GO:1901564 74 0.058
regulation of chromosome segregation GO:0051983 1 0.058
Human Mouse
single organism biosynthetic process GO:0044711 71 0.057
regulation of cell activation GO:0050865 1 0.057
response to biotic stimulus GO:0009607 97 0.057
single organism intracellular transport GO:1902582 25 0.057
Worm
cellular response to molecule of bacterial origin GO:0071219 3 0.057
golgi vesicle transport GO:0048193 3 0.057
positive regulation of cell differentiation GO:0045597 30 0.057
regulation of cell differentiation GO:0045595 142 0.056
Mouse Fly
membrane invagination GO:0010324 1 0.056
cellular localization GO:0051641 97 0.056
Mouse Worm Fly
multicellular organism reproduction GO:0032504 35 0.056
Mouse
cellular component disassembly GO:0022411 1 0.056
regulation of cell cycle GO:0051726 52 0.055
Human Mouse Fly
positive regulation of multicellular organismal process GO:0051240 52 0.054
positive regulation of muscle cell differentiation GO:0051149 1 0.054
chemosensory behavior GO:0007635 1 0.054
regulation of reproductive process GO:2000241 4 0.054
negative regulation of kinase activity GO:0033673 4 0.054
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.053
oocyte development GO:0048599 14 0.053
protein phosphorylation GO:0006468 47 0.053
Human
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.053
regulation of molecular function GO:0065009 70 0.052
Human Mouse
regulation of developmental growth GO:0048638 38 0.052
Mouse Fly
cell division GO:0051301 20 0.052
Human Mouse
chordate embryonic development GO:0043009 271 0.052
negative regulation of signal transduction GO:0009968 94 0.052
Human Mouse
convergent extension involved in gastrulation GO:0060027 71 0.051
Zebrafish
regulation of protein catabolic process GO:0042176 1 0.051
Human Mouse
ameboidal type cell migration GO:0001667 143 0.051
Mouse
growth GO:0040007 174 0.051
Mouse Fly
striated muscle cell differentiation GO:0051146 129 0.050
peptidyl threonine phosphorylation GO:0018107 1 0.050
locomotor rhythm GO:0045475 3 0.050
Mouse
positive regulation of transcription dna templated GO:0045893 57 0.049
negative regulation of response to stimulus GO:0048585 104 0.049
Human Mouse Fly
regulation of binding GO:0051098 3 0.049
regulation of response to nutrient levels GO:0032107 1 0.049
fertilization GO:0009566 3 0.049
cellular response to starvation GO:0009267 1 0.049
cellular component assembly GO:0022607 170 0.048
Human Mouse Fly
lipid storage GO:0019915 1 0.048
Fly
cell cycle process GO:0022402 53 0.048
Human Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.048
cytoplasm organization GO:0007028 4 0.048
regulation of response to cytokine stimulus GO:0060759 3 0.048
regulation of protein complex assembly GO:0043254 3 0.048
positive regulation of programmed cell death GO:0043068 29 0.047
Mouse
regulation of synapse organization GO:0050807 3 0.047
meiotic cell cycle process GO:1903046 3 0.047
cellular response to biotic stimulus GO:0071216 3 0.047
nucleobase containing compound biosynthetic process GO:0034654 205 0.047
Human
regulation of cytokine production GO:0001817 3 0.047
regulation of synapse assembly GO:0051963 3 0.047
stem cell differentiation GO:0048863 117 0.047
regulation of cellular component organization GO:0051128 86 0.046
Human Mouse Fly
negative regulation of map kinase activity GO:0043407 2 0.046
macromolecule biosynthetic process GO:0009059 227 0.046
Human
negative regulation of protein localization to nucleus GO:1900181 2 0.046
Worm
negative regulation of secretion GO:0051048 2 0.045
cellular catabolic process GO:0044248 27 0.045
Human Mouse Fly
regulation of cell substrate adhesion GO:0010810 1 0.045
Human
rna localization GO:0006403 4 0.045
regulation of protein phosphorylation GO:0001932 18 0.044
Human
regulation of neurological system process GO:0031644 2 0.044
Mouse
protein demethylation GO:0006482 2 0.044
gtp metabolic process GO:0046039 4 0.044
regulation of stem cell proliferation GO:0072091 2 0.044
negative regulation of neurogenesis GO:0050768 20 0.043
Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.043
Human
single organism reproductive process GO:0044702 40 0.043
Mouse
regulation of gene expression epigenetic GO:0040029 11 0.043
negative regulation of signaling GO:0023057 96 0.043
Human Mouse
regulation of phosphorylation GO:0042325 26 0.042
Human
organic substance transport GO:0071702 58 0.042
Worm
response to monosaccharide GO:0034284 3 0.042
cellular response to endogenous stimulus GO:0071495 68 0.042
Fly
cell death in response to oxidative stress GO:0036473 2 0.041
pronuclear migration GO:0035046 1 0.041
signal transduction by phosphorylation GO:0023014 18 0.041
protein acylation GO:0043543 3 0.041
macroautophagy GO:0016236 1 0.041
response to uv GO:0009411 3 0.040
cognition GO:0050890 1 0.040
Mouse Worm
positive regulation of cell motility GO:2000147 11 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.039
Human Mouse
regulation of neuron projection development GO:0010975 40 0.039
Mouse Fly
spindle assembly GO:0051225 2 0.039
cellular carbohydrate metabolic process GO:0044262 4 0.039
Human
regulation of protein targeting GO:1903533 2 0.039
Worm
regulation of cell shape GO:0008360 1 0.039
Fly
myeloid cell development GO:0061515 32 0.039
ubiquitin dependent protein catabolic process GO:0006511 3 0.039
Human Mouse
regulation of response to oxidative stress GO:1902882 2 0.039
positive regulation of nucleic acid templated transcription GO:1903508 57 0.038
cytoskeleton organization GO:0007010 96 0.038
Mouse Fly
neurotransmitter secretion GO:0007269 2 0.038
interspecies interaction between organisms GO:0044419 4 0.038
regulation of proteolysis GO:0030162 24 0.038
Human Mouse
negative regulation of nervous system development GO:0051961 22 0.037
Mouse Fly
regulation of protein import into nucleus GO:0042306 2 0.037
Worm
positive regulation of secretion GO:0051047 1 0.037
regulation of programmed cell death GO:0043067 101 0.037
Mouse
response to lipid GO:0033993 60 0.037
response to other organism GO:0051707 97 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.037
synaptic growth at neuromuscular junction GO:0051124 2 0.037
single fertilization GO:0007338 3 0.036
cellular component assembly involved in morphogenesis GO:0010927 107 0.036
regulation of cell death GO:0010941 103 0.036
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.036
Human
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.036
protein complex disassembly GO:0043241 1 0.036
gtp catabolic process GO:0006184 2 0.036
negative regulation of protein complex assembly GO:0031333 1 0.035
axis specification GO:0009798 43 0.035
regulation of cellular component movement GO:0051270 55 0.035
Human
negative regulation of metabolic process GO:0009892 86 0.035
Human
regulation of anatomical structure morphogenesis GO:0022603 130 0.035
Mouse Fly
regulation of erk1 and erk2 cascade GO:0070372 4 0.035
modification dependent macromolecule catabolic process GO:0043632 3 0.035
Human Mouse
wound healing GO:0042060 90 0.035
phagocytosis GO:0006909 3 0.035
mitotic cell cycle embryonic GO:0045448 2 0.035
positive regulation of cell adhesion GO:0045785 1 0.034
regulation of kinase activity GO:0043549 15 0.034
Human
negative regulation of apoptotic process GO:0043066 55 0.034
Mouse
protein dephosphorylation GO:0006470 3 0.034
Human Worm Fly
protein secretion GO:0009306 1 0.034
response to nutrient GO:0007584 3 0.034
organelle localization GO:0051640 49 0.034
Mouse
peptidyl serine modification GO:0018209 2 0.034
negative regulation of intracellular transport GO:0032387 3 0.034
Worm
regulation of cell morphogenesis GO:0022604 42 0.034
Mouse Fly
negative regulation of cell cycle GO:0045786 14 0.034
Human
erk1 and erk2 cascade GO:0070371 4 0.033
female gonad development GO:0008585 4 0.033
b cell differentiation GO:0030183 1 0.033
regulation of cell cycle process GO:0010564 20 0.033
Human Mouse
response to superoxide GO:0000303 2 0.033
exocytosis GO:0006887 1 0.033
female sex differentiation GO:0046660 4 0.032
histone demethylation GO:0016577 2 0.032
sexual reproduction GO:0019953 36 0.032
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.032
embryonic limb morphogenesis GO:0030326 2 0.032
ion transport GO:0006811 114 0.031
positive regulation of rna biosynthetic process GO:1902680 57 0.031
cellular response to stress GO:0033554 62 0.031
Fly
internal protein amino acid acetylation GO:0006475 2 0.031
leukocyte proliferation GO:0070661 1 0.031
mapk cascade GO:0000165 18 0.031
regulation of protein polymerization GO:0032271 2 0.031
rna biosynthetic process GO:0032774 181 0.031
Human
regulation of protein ubiquitination GO:0031396 3 0.030
Human Mouse
pole plasm assembly GO:0007315 4 0.030
positive regulation of cell activation GO:0050867 1 0.030
determination of dorsal ventral asymmetry GO:0048262 34 0.030
germ cell development GO:0007281 22 0.030
enzyme linked receptor protein signaling pathway GO:0007167 106 0.030
Fly
positive regulation of stem cell proliferation GO:2000648 1 0.030
taxis GO:0042330 109 0.030
Worm
programmed cell death GO:0012501 119 0.030
Mouse Fly
protein complex biogenesis GO:0070271 30 0.030
regulation of dendrite morphogenesis GO:0048814 3 0.030
Mouse
positive regulation of cell migration GO:0030335 11 0.029
sequestering of metal ion GO:0051238 3 0.029
negative regulation of epithelial cell proliferation GO:0050680 1 0.029
Mouse
heart development GO:0007507 313 0.029
Mouse
translational initiation GO:0006413 3 0.029
wnt signaling pathway GO:0016055 80 0.028
Human
positive regulation of cellular component movement GO:0051272 11 0.028
anterior posterior pattern specification GO:0009952 152 0.028
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
Human
negative regulation of programmed cell death GO:0043069 58 0.028
Mouse
cell maturation GO:0048469 23 0.028
Fly
immune response regulating signaling pathway GO:0002764 5 0.028
viral process GO:0016032 1 0.028
cellular protein catabolic process GO:0044257 4 0.028
Human Mouse
negative regulation of cytoplasmic transport GO:1903650 2 0.028
Worm
cell type specific apoptotic process GO:0097285 22 0.027
Mouse
regulation of oocyte development GO:0060281 3 0.027
microtubule organizing center organization GO:0031023 1 0.027
negative regulation of protein import into nucleus GO:0042308 2 0.027
Worm
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.027
synaptic vesicle localization GO:0097479 1 0.027
Mouse
peptidyl threonine modification GO:0018210 1 0.027
response to bacterium GO:0009617 58 0.027
response to inorganic substance GO:0010035 38 0.027
macromolecule localization GO:0033036 54 0.027
Worm Fly
negative regulation of nuclear division GO:0051784 3 0.027
oogenesis GO:0048477 14 0.027
muscle structure development GO:0061061 196 0.027
Fly
guanosine containing compound metabolic process GO:1901068 4 0.027
cell matrix adhesion GO:0007160 4 0.027
Human
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.026
membrane fusion GO:0061025 2 0.026
macromolecular complex disassembly GO:0032984 1 0.026
development of primary female sexual characteristics GO:0046545 4 0.026
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.026
positive regulation of striated muscle cell differentiation GO:0051155 1 0.026
nuclear division GO:0000280 23 0.026
Human Mouse
skeletal system development GO:0001501 181 0.026
cellular response to dna damage stimulus GO:0006974 24 0.026
stem cell development GO:0048864 82 0.025
negative regulation of mitosis GO:0045839 3 0.025
meiotic spindle organization GO:0000212 1 0.025
organophosphate metabolic process GO:0019637 37 0.025
oocyte anterior posterior axis specification GO:0007314 4 0.025
ras protein signal transduction GO:0007265 7 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.025
negative regulation of secretion by cell GO:1903531 2 0.025
negative regulation of sequestering of calcium ion GO:0051283 4 0.025
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
defense response GO:0006952 47 0.024
Fly
positive regulation of striated muscle tissue development GO:0045844 1 0.024
protein polymerization GO:0051258 4 0.024
regulation of mapk cascade GO:0043408 14 0.024
positive regulation of translation GO:0045727 1 0.024
regulation of autophagy GO:0010506 3 0.024
Fly
protein acetylation GO:0006473 2 0.024
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.024
Worm
histone lysine demethylation GO:0070076 2 0.024
neuroblast proliferation GO:0007405 2 0.024
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.024
central nervous system development GO:0007417 387 0.024
Mouse
regulation of cell projection organization GO:0031344 44 0.024
Mouse Fly
apoptotic signaling pathway GO:0097190 23 0.023
Mouse
response to nutrient levels GO:0031667 10 0.023
Fly
intracellular transport GO:0046907 32 0.023
Worm
epithelial cell differentiation GO:0030855 116 0.023
organelle assembly GO:0070925 110 0.023
membrane organization GO:0061024 21 0.023
Mouse
canonical wnt signaling pathway GO:0060070 48 0.023
Human
lateral inhibition GO:0046331 1 0.023
catabolic process GO:0009056 32 0.023
Human Mouse Fly
nuclear migration GO:0007097 3 0.023
regulation of circadian rhythm GO:0042752 4 0.023
actin filament polymerization GO:0030041 2 0.023
internal peptidyl lysine acetylation GO:0018393 2 0.022
positive regulation of immune effector process GO:0002699 3 0.022
erythrocyte differentiation GO:0030218 54 0.022
protein complex assembly GO:0006461 30 0.022
calcium ion transport into cytosol GO:0060402 3 0.022
positive regulation of protein metabolic process GO:0051247 23 0.022
Human Mouse
mononuclear cell proliferation GO:0032943 1 0.022
regulation of cellular response to oxidative stress GO:1900407 2 0.022
centrosome organization GO:0051297 1 0.022
mitotic cell cycle process GO:1903047 48 0.022
Human Mouse
cellular extravasation GO:0045123 1 0.022
regulation of cellular component size GO:0032535 30 0.022
Mouse Fly
regulation of neurotransmitter secretion GO:0046928 1 0.022
maternal determination of anterior posterior axis embryo GO:0008358 4 0.021
negative regulation of cell differentiation GO:0045596 46 0.021
Mouse Fly
peptidyl lysine acetylation GO:0018394 2 0.021
positive regulation of proteolysis GO:0045862 10 0.021
Human Mouse
rho protein signal transduction GO:0007266 5 0.021
regulation of cellular response to stress GO:0080135 20 0.021
Fly

ptena disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.070
Human
disease of cellular proliferation DOID:14566 0 0.070
Human
organ system cancer DOID:0050686 0 0.070
Human
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033