Danio rerio

90 known processes

ptenb

phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)

(Aliases: wu:fk90e11,fd16b10,fa11a08,wu:fc83f12,fk90e11,wu:fa11a08,si:bz1g13.4,fb73f10,pten,MGC123112,wu:fd16b10,fc83f12,wu:fb73f10)

ptenb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell migration GO:0016477 237 0.987
Human Mouse
central nervous system development GO:0007417 387 0.939
Mouse
regulation of cellular component organization GO:0051128 86 0.929
Human Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.864
Mouse
hemopoiesis GO:0030097 183 0.811
protein localization GO:0008104 40 0.799
Worm Fly
single organism transport GO:0044765 206 0.785
Worm
cell projection organization GO:0030030 284 0.783
Mouse Fly
chordate embryonic development GO:0043009 271 0.764
cell motility GO:0048870 244 0.721
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.711
brain development GO:0007420 293 0.705
Mouse
heart development GO:0007507 313 0.694
Mouse
wnt signaling pathway GO:0016055 80 0.682
Human
maintenance of location GO:0051235 4 0.681
Fly
tube morphogenesis GO:0035239 349 0.670
determination of left right symmetry GO:0007368 179 0.664
organic cyclic compound biosynthetic process GO:1901362 223 0.663
Human
larval development GO:0002164 2 0.656
Worm Fly
regulation of multicellular organismal development GO:2000026 223 0.653
Mouse Fly
positive regulation of biological process GO:0048518 253 0.643
Human Mouse
developmental growth GO:0048589 166 0.580
Mouse Fly
multicellular organism reproduction GO:0032504 35 0.574
Mouse
signal transduction GO:0007165 455 0.572
aromatic compound biosynthetic process GO:0019438 217 0.555
Human
growth GO:0040007 174 0.554
Mouse Fly
determination of bilateral symmetry GO:0009855 204 0.546
rna metabolic process GO:0016070 219 0.529
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.515
Human
gastrulation GO:0007369 208 0.488
nucleobase containing compound metabolic process GO:0006139 274 0.487
Human
somitogenesis GO:0001756 87 0.467
meiotic nuclear division GO:0007126 4 0.464
immune system process GO:0002376 241 0.463
hematopoietic or lymphoid organ development GO:0048534 191 0.463
embryonic organ development GO:0048568 381 0.460
embryonic organ morphogenesis GO:0048562 274 0.453
cell surface receptor signaling pathway GO:0007166 325 0.446
Human Fly
regulation of developmental process GO:0050793 247 0.445
Mouse Fly
regulation of axonogenesis GO:0050770 32 0.439
Mouse
heterocycle biosynthetic process GO:0018130 215 0.438
Human
g1 s transition of mitotic cell cycle GO:0000082 1 0.435
Human
multi organism process GO:0051704 134 0.421
Mouse
neuron projection development GO:0031175 180 0.403
Mouse Fly
regulation of synapse organization GO:0050807 3 0.402
regulation of nitrogen compound metabolic process GO:0051171 251 0.397
Human
negative regulation of biological process GO:0048519 304 0.382
Human Mouse Worm Fly
cell proliferation GO:0008283 80 0.382
Human Mouse Fly
small molecule metabolic process GO:0044281 77 0.376
Human
locomotion GO:0040011 313 0.373
Human Mouse Worm
positive regulation of transport GO:0051050 2 0.371
somite development GO:0061053 96 0.368
gene expression GO:0010467 252 0.362
Human
stem cell division GO:0017145 1 0.362
canonical wnt signaling pathway GO:0060070 48 0.359
Human
neuroblast proliferation GO:0007405 2 0.348
nucleic acid metabolic process GO:0090304 244 0.342
Human
regulation of nervous system development GO:0051960 90 0.338
Mouse Fly
axonogenesis GO:0007409 152 0.333
Mouse
convergent extension GO:0060026 118 0.332
regulation of anatomical structure morphogenesis GO:0022603 130 0.328
Mouse Fly
sexual reproduction GO:0019953 36 0.327
Mouse
cellular component movement GO:0006928 335 0.324
Human Mouse
regulation of biological quality GO:0065008 263 0.320
Human Mouse Fly
cellular component morphogenesis GO:0032989 336 0.315
Mouse Fly
regulation of multicellular organismal process GO:0051239 277 0.312
Mouse Fly
neuron differentiation GO:0030182 353 0.312
Mouse Fly
behavior GO:0007610 74 0.312
Mouse Worm
cellular aromatic compound metabolic process GO:0006725 295 0.308
Human Fly
digestive tract development GO:0048565 265 0.297
regionalization GO:0003002 274 0.293
cellular biosynthetic process GO:0044249 286 0.291
Human
response to stress GO:0006950 263 0.290
Mouse Worm Fly
regulation of establishment of protein localization GO:0070201 4 0.289
Worm
axon development GO:0061564 166 0.287
Mouse Fly
positive regulation of cellular process GO:0048522 201 0.283
Human Mouse
system process GO:0003008 185 0.279
Mouse Worm
regulation of response to stimulus GO:0048583 269 0.277
regulation of protein localization to nucleus GO:1900180 2 0.277
Worm
regulation of protein transport GO:0051223 3 0.269
Worm
heart morphogenesis GO:0003007 156 0.261
regulation of macromolecule biosynthetic process GO:0010556 225 0.260
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.258
Human
regulation of cell communication GO:0010646 232 0.258
stem cell differentiation GO:0048863 117 0.254
response to external stimulus GO:0009605 264 0.253
Mouse Worm Fly
regulation of canonical wnt signaling pathway GO:0060828 34 0.253
neuron projection morphogenesis GO:0048812 161 0.253
Mouse
regulation of nucleocytoplasmic transport GO:0046822 2 0.245
Worm
nitrogen compound metabolic process GO:0006807 319 0.245
Human
regulation of biosynthetic process GO:0009889 250 0.244
Human
response to wounding GO:0009611 116 0.241
Fly
ear development GO:0043583 127 0.240
positive regulation of signal transduction GO:0009967 56 0.237
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.234
positive regulation of cell cycle GO:0045787 3 0.234
Human Mouse
neurological system process GO:0050877 62 0.228
Mouse Worm
organelle organization GO:0006996 227 0.223
Human Mouse Fly
localization of cell GO:0051674 244 0.222
Human Mouse
cellular ketone metabolic process GO:0042180 11 0.218
cell cycle process GO:0022402 53 0.216
Human Mouse
macromolecule biosynthetic process GO:0009059 227 0.214
Human
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.213
Mouse
regeneration GO:0031099 91 0.204
Fly
cellular protein localization GO:0034613 20 0.201
Worm Fly
neuron development GO:0048666 262 0.200
Mouse Fly
muscle tissue development GO:0060537 110 0.200
Mouse
negative regulation of phosphorus metabolic process GO:0010563 13 0.200
Human
protein import GO:0017038 3 0.197
Worm
diencephalon development GO:0021536 58 0.197
positive regulation of muscle organ development GO:0048636 1 0.196
wound healing GO:0042060 90 0.193
i kappab kinase nf kappab signaling GO:0007249 4 0.190
cognition GO:0050890 1 0.189
Mouse Worm
cellular component biogenesis GO:0044085 178 0.186
Human Mouse Fly
regulation of neurogenesis GO:0050767 87 0.183
Mouse Fly
embryonic appendage morphogenesis GO:0035113 30 0.181
generation of neurons GO:0048699 385 0.177
Mouse Fly
protein metabolic process GO:0019538 183 0.177
Human Mouse Worm Fly
tissue regeneration GO:0042246 74 0.176
phosphate containing compound metabolic process GO:0006796 108 0.175
synaptic growth at neuromuscular junction GO:0051124 2 0.174
cellular nitrogen compound metabolic process GO:0034641 290 0.174
Human
protein import into nucleus GO:0006606 3 0.173
Worm
positive regulation of muscle cell differentiation GO:0051149 1 0.172
specification of symmetry GO:0009799 204 0.169
cell fate commitment GO:0045165 99 0.168
Fly
regulation of protein targeting GO:1903533 2 0.167
Worm
cell morphogenesis GO:0000902 289 0.166
Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.165
Human Mouse Worm Fly
heterocycle metabolic process GO:0046483 290 0.164
Human
regulation of response to stress GO:0080134 36 0.162
Fly
regulation of intracellular protein transport GO:0033157 3 0.161
Worm
oxoacid metabolic process GO:0043436 31 0.161
synaptic transmission GO:0007268 35 0.158
Mouse
cell projection morphogenesis GO:0048858 244 0.156
Mouse
regulation of cell differentiation GO:0045595 142 0.156
Mouse Fly
endothelial cell fate commitment GO:0060839 3 0.156
regulation of cellular ketone metabolic process GO:0010565 7 0.155
striated muscle tissue development GO:0014706 110 0.153
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.153
organic substance biosynthetic process GO:1901576 289 0.153
Human
forebrain development GO:0030900 96 0.152
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.152
Human Fly
positive regulation of muscle tissue development GO:1901863 1 0.151
immune system development GO:0002520 191 0.150
head development GO:0060322 303 0.146
Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.144
negative regulation of developmental process GO:0051093 65 0.141
Mouse Fly
regulation of dendrite development GO:0050773 3 0.141
Mouse Fly
segmentation GO:0035282 97 0.140
periodic partitioning GO:0007365 1 0.140
organic acid metabolic process GO:0006082 31 0.140
regulation of cell morphogenesis GO:0022604 42 0.139
Mouse Fly
regulation of rna biosynthetic process GO:2001141 213 0.137
Human
regulation of transcription dna templated GO:0006355 213 0.135
Human
negative regulation of gene expression GO:0010629 65 0.133
digestive tract morphogenesis GO:0048546 231 0.133
detection of stimulus GO:0051606 29 0.133
positive regulation of biosynthetic process GO:0009891 68 0.132
lipid storage GO:0019915 1 0.132
Fly
cell cell signaling GO:0007267 52 0.131
Mouse
positive regulation of rna metabolic process GO:0051254 59 0.131
cellular response to organic substance GO:0071310 105 0.130
Fly
regulation of synapse assembly GO:0051963 3 0.129
response to endogenous stimulus GO:0009719 83 0.127
Fly
regulation of cytoplasmic transport GO:1903649 4 0.126
Worm
mesenchymal cell differentiation GO:0048762 87 0.125
regulation of metabolic process GO:0019222 359 0.125
Human Mouse Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.123
negative regulation of kinase activity GO:0033673 4 0.123
Human
actin filament based process GO:0030029 64 0.123
Fly
positive regulation of cellular metabolic process GO:0031325 94 0.123
Human Mouse
regulation of transferase activity GO:0051338 16 0.123
Human Mouse
cell part morphogenesis GO:0032990 246 0.120
Mouse
mesenchyme development GO:0060485 127 0.120
chemotaxis GO:0006935 104 0.118
Worm
determination of heart left right asymmetry GO:0061371 117 0.116
regulation of wnt signaling pathway GO:0030111 53 0.115
protein localization to nucleus GO:0034504 3 0.115
Worm
cellular response to hormone stimulus GO:0032870 39 0.115
Fly
response to abiotic stimulus GO:0009628 122 0.115
Worm
phosphorus metabolic process GO:0006793 109 0.113
negative regulation of protein phosphorylation GO:0001933 4 0.113
Human
stem cell proliferation GO:0072089 4 0.112
cell cycle g1 s phase transition GO:0044843 1 0.109
Human
positive regulation of signaling GO:0023056 56 0.108
Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.108
Human Mouse
regulation of meiotic cell cycle GO:0051445 1 0.108
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.107
enzyme linked receptor protein signaling pathway GO:0007167 106 0.107
Fly
response to organic substance GO:0010033 153 0.107
Fly
embryonic limb morphogenesis GO:0030326 2 0.106
fin regeneration GO:0031101 51 0.106
regulation of phosphorus metabolic process GO:0051174 43 0.105
Human
single organism reproductive process GO:0044702 40 0.104
Mouse
heart looping GO:0001947 94 0.104
nuclear division GO:0000280 23 0.103
Human Mouse
negative regulation of protein kinase activity GO:0006469 4 0.102
Human
biosynthetic process GO:0009058 294 0.102
Human
cell death GO:0008219 121 0.100
Mouse Fly
eye development GO:0001654 277 0.100
Fly
intracellular signal transduction GO:0035556 85 0.099
transport GO:0006810 220 0.099
Worm
cilium morphogenesis GO:0060271 85 0.098
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.097
positive regulation of jnk cascade GO:0046330 3 0.097
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.096
meiotic cell cycle process GO:1903046 3 0.096
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.096
cell division GO:0051301 20 0.096
Human Mouse
bmp signaling pathway GO:0030509 52 0.096
programmed cell death GO:0012501 119 0.094
Mouse Fly
embryonic heart tube morphogenesis GO:0003143 108 0.094
digestive system development GO:0055123 289 0.094
multicellular organismal reproductive process GO:0048609 35 0.093
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.093
Human Mouse
endocardial cushion formation GO:0003272 2 0.092
striated muscle cell differentiation GO:0051146 129 0.091
stem cell maintenance GO:0019827 4 0.091
regulation of signaling GO:0023051 235 0.090
vasculature development GO:0001944 278 0.090
segment polarity determination GO:0007367 1 0.089
mesenchymal cell development GO:0014031 78 0.089
regulation of primary metabolic process GO:0080090 311 0.088
Human Mouse
nucleic acid templated transcription GO:0097659 181 0.087
Human
outflow tract morphogenesis GO:0003151 1 0.087
sensory organ morphogenesis GO:0090596 200 0.086
Fly
cellular localization GO:0051641 97 0.086
Mouse Worm Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.085
regulation of bmp signaling pathway GO:0030510 39 0.083
regulation of cardiac muscle tissue development GO:0055024 1 0.083
stem cell development GO:0048864 82 0.082
response to bacterium GO:0009617 58 0.081
liver development GO:0001889 96 0.081
embryonic cranial skeleton morphogenesis GO:0048701 90 0.078
positive regulation of metabolic process GO:0009893 108 0.078
Human Mouse
pronuclear migration GO:0035046 1 0.078
single organism nuclear import GO:1902593 3 0.077
Worm
single organism localization GO:1902578 225 0.077
Mouse Worm
carboxylic acid metabolic process GO:0019752 22 0.077
regulation of neuron differentiation GO:0045664 56 0.077
Mouse Fly
positive regulation of striated muscle tissue development GO:0045844 1 0.077
homeostatic process GO:0042592 142 0.076
ameboidal type cell migration GO:0001667 143 0.076
Mouse
reproduction GO:0000003 40 0.076
Mouse
cellular macromolecule localization GO:0070727 21 0.075
Worm Fly
regulation of molecular function GO:0065009 70 0.075
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.075
positive regulation of cellular component biogenesis GO:0044089 3 0.074
epithelial tube morphogenesis GO:0060562 148 0.074
appendage morphogenesis GO:0035107 56 0.074
positive regulation of multicellular organismal process GO:0051240 52 0.074
negative regulation of signaling GO:0023057 96 0.074
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.074
Human Mouse Fly
regulation of protein complex assembly GO:0043254 3 0.074
anatomical structure homeostasis GO:0060249 36 0.073
blood vessel morphogenesis GO:0048514 216 0.073
Mouse
positive regulation of cell communication GO:0010647 56 0.073
Mouse
fertilization GO:0009566 3 0.072
regulation of rna metabolic process GO:0051252 224 0.072
Human
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.071
muscle organ development GO:0007517 101 0.071
regulation of nucleic acid templated transcription GO:1903506 213 0.070
Human
regulation of cell shape GO:0008360 1 0.070
Fly
positive regulation of map kinase activity GO:0043406 3 0.070
organelle fission GO:0048285 23 0.070
Human Mouse
embryonic neurocranium morphogenesis GO:0048702 15 0.070
cellular response to endogenous stimulus GO:0071495 68 0.069
Fly
cell fate specification GO:0001708 68 0.068
axon guidance GO:0007411 86 0.068
cell cycle GO:0007049 93 0.067
Human Mouse Fly
regulation of blood circulation GO:1903522 32 0.067
regulation of cellular biosynthetic process GO:0031326 245 0.067
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.067
single organism organelle organization GO:1902589 199 0.066
Human Mouse Fly
macromolecule modification GO:0043412 111 0.066
Human Mouse Worm Fly
regulation of protein phosphorylation GO:0001932 18 0.066
Human
negative regulation of biosynthetic process GO:0009890 55 0.066
regulation of signal transduction GO:0009966 225 0.066
regulation of intracellular signal transduction GO:1902531 57 0.065
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.064
positive regulation of molecular function GO:0044093 33 0.064
Human Mouse
defense response GO:0006952 47 0.064
Fly
cellular lipid metabolic process GO:0044255 36 0.063
positive regulation of striated muscle cell differentiation GO:0051155 1 0.063
response to chemical GO:0042221 320 0.063
Worm Fly
meiosis i GO:0007127 1 0.062
regulation of cellular amine metabolic process GO:0033238 0 0.062
nucleobase containing compound biosynthetic process GO:0034654 205 0.061
Human
cellular component assembly GO:0022607 170 0.061
Human Mouse Fly
positive regulation of transcription dna templated GO:0045893 57 0.061
non canonical wnt signaling pathway GO:0035567 13 0.061
transcription dna templated GO:0006351 181 0.061
Human
protein modification process GO:0036211 100 0.061
Human Mouse Worm Fly
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.061
developmental growth involved in morphogenesis GO:0060560 86 0.060
ras protein signal transduction GO:0007265 7 0.059
cellular nitrogen compound biosynthetic process GO:0044271 218 0.057
Human
regulation of synaptic plasticity GO:0048167 1 0.057
Mouse
regulation of programmed cell death GO:0043067 101 0.057
Mouse
membrane organization GO:0061024 21 0.056
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.056
Mouse Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.056
neuromuscular synaptic transmission GO:0007274 2 0.055
regulation of heart growth GO:0060420 2 0.055
rna biosynthetic process GO:0032774 181 0.055
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.055
Mouse
single organism cellular localization GO:1902580 46 0.054
Mouse Worm
organic substance transport GO:0071702 58 0.054
Worm
regulation of protein import into nucleus GO:0042306 2 0.054
Worm
positive regulation of secretion by cell GO:1903532 1 0.054
single organism membrane organization GO:0044802 20 0.053
Mouse
protein phosphorylation GO:0006468 47 0.053
Human
taxis GO:0042330 109 0.053
Worm
muscle structure development GO:0061061 196 0.053
Fly
determination of left right asymmetry in nervous system GO:0035545 4 0.053
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.052
Human Mouse
regulation of receptor activity GO:0010469 2 0.052
regulation of anatomical structure size GO:0090066 33 0.052
Mouse Fly
regulation of cell development GO:0060284 100 0.051
Mouse Fly
regulation of kinase activity GO:0043549 15 0.051
Human
arterial endothelial cell differentiation GO:0060842 2 0.051
regulation of cell matrix adhesion GO:0001952 1 0.051
Human
protein targeting to nucleus GO:0044744 3 0.051
Worm
positive regulation of stress activated mapk cascade GO:0032874 3 0.050
lateral inhibition GO:0046331 1 0.050
negative regulation of apoptotic process GO:0043066 55 0.050
Mouse
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.050
positive regulation of cytokine production GO:0001819 2 0.050
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.049
regulation of growth GO:0040008 42 0.049
Mouse Fly
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.049
regulation of establishment of planar polarity GO:0090175 4 0.048
Fly
pronephros development GO:0048793 69 0.048
convergent extension involved in gastrulation GO:0060027 71 0.048
positive regulation of secretion GO:0051047 1 0.048
response to biotic stimulus GO:0009607 97 0.048
negative regulation of cellular metabolic process GO:0031324 77 0.047
Human
protein secretion GO:0009306 1 0.047
establishment of localization GO:0051234 244 0.047
Worm
regulation of cellular component biogenesis GO:0044087 12 0.047
Human Mouse Fly
brain morphogenesis GO:0048854 18 0.047
Mouse
camera type eye development GO:0043010 222 0.046
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.046
embryonic pattern specification GO:0009880 44 0.045
regulation of multicellular organism growth GO:0040014 4 0.045
Fly
sensory organ development GO:0007423 393 0.044
cellular protein catabolic process GO:0044257 4 0.044
Human Mouse
epithelial cell migration GO:0010631 25 0.044
Mouse
hepaticobiliary system development GO:0061008 98 0.044
dorsal ventral pattern formation GO:0009953 125 0.044
leukocyte activation GO:0045321 12 0.043
regulation of organ morphogenesis GO:2000027 35 0.043
Fly
epithelial cell development GO:0002064 42 0.042
defense response to other organism GO:0098542 33 0.042
negative regulation of macromolecule metabolic process GO:0010605 76 0.042
Human
response to other organism GO:0051707 97 0.041
phagocytosis GO:0006909 3 0.041
positive regulation of phosphorus metabolic process GO:0010562 21 0.041
gamete generation GO:0007276 33 0.041
cellular response to extracellular stimulus GO:0031668 2 0.041
regulation of cytoskeleton organization GO:0051493 11 0.041
anterior posterior pattern specification GO:0009952 152 0.041
positive regulation of nucleic acid templated transcription GO:1903508 57 0.040
embryonic heart tube development GO:0035050 133 0.040
negative regulation of phosphate metabolic process GO:0045936 13 0.040
Human
regulation of embryonic development GO:0045995 47 0.039
regulation of cell cycle process GO:0010564 20 0.039
Human Mouse
cellular protein modification process GO:0006464 100 0.039
Human Mouse Worm Fly
regulation of developmental growth GO:0048638 38 0.039
Mouse Fly
regulation of cytokine production GO:0001817 3 0.039
positive regulation of catabolic process GO:0009896 4 0.039
Human Mouse
regulation of cell substrate adhesion GO:0010810 1 0.038
Human
b cell activation GO:0042113 2 0.038
regulation of phosphate metabolic process GO:0019220 43 0.038
Human
endocardial cushion morphogenesis GO:0003203 3 0.037
regulation of cardiac muscle cell differentiation GO:2000725 1 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.037
negative regulation of cellular process GO:0048523 283 0.037
Human Mouse Worm Fly
regulation of cell cycle GO:0051726 52 0.037
Human Mouse Fly
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.037
reproductive process GO:0022414 40 0.037
Mouse
establishment of localization in cell GO:0051649 77 0.037
Worm
positive regulation of cell division GO:0051781 2 0.037
Human Mouse
optic placode formation GO:0001743 4 0.036
circulatory system process GO:0003013 87 0.036
metal ion transport GO:0030001 58 0.036
single fertilization GO:0007338 3 0.036
regulation of gene expression GO:0010468 265 0.036
Human
retinoic acid metabolic process GO:0042573 9 0.036
lipid metabolic process GO:0006629 52 0.035
cellular amine metabolic process GO:0044106 2 0.035
regulation of cellular protein metabolic process GO:0032268 52 0.035
Human Mouse
b cell differentiation GO:0030183 1 0.035
cellular protein metabolic process GO:0044267 129 0.035
Human Mouse Worm Fly
negative regulation of signal transduction GO:0009968 94 0.035
Human Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.034
single organism metabolic process GO:0044710 217 0.034
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.034
regulation of vasculature development GO:1901342 33 0.034
macromolecule localization GO:0033036 54 0.033
Worm Fly
cellular amino acid metabolic process GO:0006520 7 0.033
positive regulation of gene expression GO:0010628 71 0.033
positive regulation of protein metabolic process GO:0051247 23 0.033
Human Mouse
regulation of dendrite morphogenesis GO:0048814 3 0.033
Mouse
mitotic cell cycle phase transition GO:0044772 9 0.033
Human Mouse
urogenital system development GO:0001655 97 0.033
Mouse
blood circulation GO:0008015 87 0.033
adherens junction organization GO:0034332 4 0.032
Human
regulation of mitotic cell cycle phase transition GO:1901990 8 0.032
Human Mouse
epithelial cell morphogenesis GO:0003382 2 0.032
regulation of neurological system process GO:0031644 2 0.032
Mouse
small gtpase mediated signal transduction GO:0007264 8 0.032
regulation of epithelial cell proliferation GO:0050678 3 0.031
Mouse
negative regulation of cell communication GO:0010648 96 0.031
Human Mouse
response to light stimulus GO:0009416 46 0.031
regulation of cell migration GO:0030334 40 0.031
Human
negative regulation of cell death GO:0060548 60 0.031
Mouse
erk1 and erk2 cascade GO:0070371 4 0.030
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.030
Human
appendage development GO:0048736 80 0.030
developmental process involved in reproduction GO:0003006 27 0.030
Mouse
cytoskeleton dependent cytokinesis GO:0061640 3 0.030
otolith development GO:0048840 32 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.030
Human
cardiac cell fate commitment GO:0060911 1 0.030
positive regulation of cell proliferation GO:0008284 15 0.030
Mouse
regulation of transport GO:0051049 45 0.029
Worm
protein dephosphorylation GO:0006470 3 0.029
Human Worm Fly
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.029
embryonic pectoral fin morphogenesis GO:0035118 24 0.029
cellular carbohydrate metabolic process GO:0044262 4 0.029
Human
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.029
blood vessel endothelial cell differentiation GO:0060837 2 0.029
multi organism reproductive process GO:0044703 36 0.028
Mouse
endocytosis GO:0006897 16 0.028
tissue remodeling GO:0048771 4 0.028
positive regulation of catalytic activity GO:0043085 25 0.028
Human Mouse
phosphorylation GO:0016310 69 0.028
Human
meiotic chromosome segregation GO:0045132 3 0.027
regulation of bone remodeling GO:0046850 2 0.027
regulation of exocytosis GO:0017157 1 0.027
female meiotic division GO:0007143 2 0.027
aorta development GO:0035904 4 0.027
cortical actin cytoskeleton organization GO:0030866 1 0.027
germ line stem cell division GO:0042078 1 0.026
positive regulation of developmental process GO:0051094 50 0.026
viral process GO:0016032 1 0.026
regulation of filopodium assembly GO:0051489 2 0.026
embryonic skeletal system morphogenesis GO:0048704 93 0.026
endoderm formation GO:0001706 29 0.026
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.026
Human Mouse
meiotic cell cycle GO:0051321 5 0.026
nuclear import GO:0051170 3 0.025
Worm
endocardium morphogenesis GO:0003160 4 0.025
cytokinesis GO:0000910 3 0.025
positive regulation of cellular protein metabolic process GO:0032270 22 0.025
Human Mouse
leukocyte differentiation GO:0002521 25 0.025
epithelial cell differentiation GO:0030855 116 0.025
detection of external stimulus GO:0009581 24 0.025
hematopoietic progenitor cell differentiation GO:0002244 23 0.025
lamellipodium assembly GO:0030032 1 0.025
morphogenesis of an epithelial fold GO:0060571 1 0.025
angiogenesis GO:0001525 158 0.025
Mouse
positive regulation of programmed cell death GO:0043068 29 0.025
Mouse
cardiac chamber development GO:0003205 19 0.025
negative regulation of protein localization to nucleus GO:1900181 2 0.025
Worm
positive regulation of response to stimulus GO:0048584 80 0.024
Mouse
blood vessel development GO:0001568 246 0.024
hepatocyte proliferation GO:0072574 2 0.024
cellular response to external stimulus GO:0071496 2 0.024
negative regulation of cellular biosynthetic process GO:0031327 55 0.024
regulation of circadian rhythm GO:0042752 4 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.024
single organism intracellular transport GO:1902582 25 0.024
Worm
hair cell differentiation GO:0035315 32 0.023
leukocyte proliferation GO:0070661 1 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
Worm
embryonic skeletal system development GO:0048706 97 0.023
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.023
regulation of transmembrane transporter activity GO:0022898 2 0.023
central nervous system neuron differentiation GO:0021953 74 0.023
Mouse
positive regulation of apoptotic process GO:0043065 29 0.023
Mouse
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.023
regulation of cell motility GO:2000145 46 0.023
Human
organophosphate metabolic process GO:0019637 37 0.023
regulation of localization GO:0032879 104 0.023
Human Mouse Worm
kidney development GO:0001822 92 0.023

ptenb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.207
musculoskeletal system disease DOID:17 0 0.043
nervous system disease DOID:863 0 0.038
cancer DOID:162 0 0.027
Human
disease of cellular proliferation DOID:14566 0 0.027
Human
muscular disease DOID:0080000 0 0.024
muscle tissue disease DOID:66 0 0.024