Danio rerio

0 known processes

ptgesl

prostaglandin E synthase 2-like

(Aliases: zgc:56527,ptges2,MGC174076,MGC56527)

ptgesl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to drug GO:0042493 3 0.649
oxidation reduction process GO:0055114 41 0.631
small molecule catabolic process GO:0044282 3 0.344
small molecule metabolic process GO:0044281 77 0.320
response to chemical GO:0042221 320 0.310
very long chain fatty acid metabolic process GO:0000038 4 0.261
regulation of primary metabolic process GO:0080090 311 0.255
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.242
Mouse
response to stress GO:0006950 263 0.227
cellular aromatic compound metabolic process GO:0006725 295 0.205
Mouse
aging GO:0007568 2 0.201
nucleic acid metabolic process GO:0090304 244 0.200
Mouse
regulation of biological quality GO:0065008 263 0.199
hormone biosynthetic process GO:0042446 3 0.187
single organism metabolic process GO:0044710 217 0.182
response to organic substance GO:0010033 153 0.181
carboxylic acid metabolic process GO:0019752 22 0.180
oxoacid metabolic process GO:0043436 31 0.169
larval development GO:0002164 2 0.167
organic acid metabolic process GO:0006082 31 0.166
nitrogen compound metabolic process GO:0006807 319 0.147
Mouse
signal transduction in absence of ligand GO:0038034 1 0.142
regulation of signal transduction GO:0009966 225 0.129
energy reserve metabolic process GO:0006112 2 0.127
atp synthesis coupled electron transport GO:0042773 1 0.124
extrinsic apoptotic signaling pathway GO:0097191 3 0.109
negative regulation of biological process GO:0048519 304 0.107
ovulation cycle GO:0042698 2 0.105
nucleobase containing compound metabolic process GO:0006139 274 0.104
Mouse
cellular biosynthetic process GO:0044249 286 0.104
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.104
synaptic vesicle transport GO:0048489 1 0.099
dicarboxylic acid metabolic process GO:0043648 1 0.098
gene expression GO:0010467 252 0.098
Mouse
cellular component assembly GO:0022607 170 0.094
cellular response to chemical stimulus GO:0070887 157 0.090
apoptotic process GO:0006915 116 0.088
cellular nitrogen compound biosynthetic process GO:0044271 218 0.088
Mouse
response to nutrient GO:0007584 3 0.088
mitochondrion organization GO:0007005 4 0.087
ribonucleoside monophosphate catabolic process GO:0009158 4 0.085
response to inorganic substance GO:0010035 38 0.085
regulation of cell communication GO:0010646 232 0.082
response to glucocorticoid GO:0051384 1 0.082
immune system process GO:0002376 241 0.082
cellular modified amino acid metabolic process GO:0006575 3 0.080
fatty acid biosynthetic process GO:0006633 4 0.079
cellular ketone metabolic process GO:0042180 11 0.078
regulation of biosynthetic process GO:0009889 250 0.075
Mouse
positive regulation of biological process GO:0048518 253 0.075
Mouse
head development GO:0060322 303 0.074
regulation of signaling GO:0023051 235 0.073
estrogen metabolic process GO:0008210 2 0.071
synaptic transmission GO:0007268 35 0.069
cell death GO:0008219 121 0.068
cellular response to lipopolysaccharide GO:0071222 3 0.068
response to corticosteroid GO:0031960 1 0.066
single organism localization GO:1902578 225 0.064
Mouse
rna biosynthetic process GO:0032774 181 0.064
Mouse
androgen metabolic process GO:0008209 2 0.064
biosynthetic process GO:0009058 294 0.063
Mouse
nucleoside monophosphate catabolic process GO:0009125 4 0.063
cellular component movement GO:0006928 335 0.061
regulation of metabolic process GO:0019222 359 0.060
Mouse
transport GO:0006810 220 0.060
Mouse
cellular respiration GO:0045333 3 0.059
establishment of localization GO:0051234 244 0.059
Mouse
fatty acid beta oxidation GO:0006635 1 0.058
cellular macromolecule metabolic process GO:0044260 391 0.058
Mouse
organelle organization GO:0006996 227 0.058
monocarboxylic acid biosynthetic process GO:0072330 12 0.058
phosphorus metabolic process GO:0006793 109 0.057
cellular localization GO:0051641 97 0.054
single organism transport GO:0044765 206 0.053
Mouse
synaptic vesicle localization GO:0097479 1 0.053
protein complex subunit organization GO:0071822 46 0.052
establishment of localization in cell GO:0051649 77 0.052
ovulation cycle process GO:0022602 2 0.051
cellular response to antibiotic GO:0071236 1 0.051
response to external stimulus GO:0009605 264 0.049
organic substance biosynthetic process GO:1901576 289 0.049
Mouse
lipid oxidation GO:0034440 1 0.049
ovarian follicle development GO:0001541 2 0.048
macromolecule biosynthetic process GO:0009059 227 0.048
Mouse
fatty acid oxidation GO:0019395 1 0.048
cellular amino acid metabolic process GO:0006520 7 0.047
rna metabolic process GO:0016070 219 0.046
Mouse
cellular hormone metabolic process GO:0034754 19 0.046
death GO:0016265 121 0.046
response to metal ion GO:0010038 34 0.046
nucleocytoplasmic transport GO:0006913 4 0.045
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.045
Mouse
nuclear transport GO:0051169 4 0.045
regulation of cytoplasmic transport GO:1903649 4 0.044
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.043
Mouse
regulation of response to stimulus GO:0048583 269 0.043
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.043
protein import GO:0017038 3 0.043
organonitrogen compound metabolic process GO:1901564 74 0.041
response to biotic stimulus GO:0009607 97 0.041
negative regulation of cellular process GO:0048523 283 0.040
macromolecule localization GO:0033036 54 0.040
cellular amine metabolic process GO:0044106 2 0.039
regulation of developmental process GO:0050793 247 0.039
positive regulation of cellular process GO:0048522 201 0.039
Mouse
immune system development GO:0002520 191 0.039
regulation of hormone secretion GO:0046883 2 0.038
female gonad development GO:0008585 4 0.038
aromatic compound biosynthetic process GO:0019438 217 0.038
Mouse
regulation of transcription dna templated GO:0006355 213 0.038
Mouse
positive regulation of transport GO:0051050 2 0.037
cellular protein catabolic process GO:0044257 4 0.037
transcription dna templated GO:0006351 181 0.037
Mouse
regulation of autophagy GO:0010506 3 0.036
reactive oxygen species biosynthetic process GO:1903409 1 0.036
myeloid cell differentiation GO:0030099 86 0.036
alcohol biosynthetic process GO:0046165 2 0.036
programmed cell death GO:0012501 119 0.036
carbohydrate biosynthetic process GO:0016051 1 0.036
regulation of establishment of protein localization GO:0070201 4 0.035
heterocycle metabolic process GO:0046483 290 0.035
Mouse
ion transport GO:0006811 114 0.035
negative regulation of hormone secretion GO:0046888 2 0.034
regulation of multicellular organism growth GO:0040014 4 0.034
organic cyclic compound metabolic process GO:1901360 301 0.034
Mouse
gland development GO:0048732 143 0.034
muscle cell development GO:0055001 115 0.033
female sex differentiation GO:0046660 4 0.033
heterocycle biosynthetic process GO:0018130 215 0.033
Mouse
response to organic cyclic compound GO:0014070 51 0.033
regulation of carbohydrate metabolic process GO:0006109 4 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.032
Mouse
endocrine hormone secretion GO:0060986 2 0.032
response to other organism GO:0051707 97 0.032
hormone secretion GO:0046879 2 0.032
lipid catabolic process GO:0016042 4 0.032
single organism biosynthetic process GO:0044711 71 0.032
hormone metabolic process GO:0042445 19 0.032
signal transduction GO:0007165 455 0.031
positive regulation of epithelial cell proliferation GO:0050679 1 0.031
regulation of epithelial cell proliferation GO:0050678 3 0.031
adult behavior GO:0030534 2 0.030
positive regulation of apoptotic signaling pathway GO:2001235 1 0.030
cell aging GO:0007569 2 0.030
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.030
cellular protein metabolic process GO:0044267 129 0.030
intracellular signal transduction GO:0035556 85 0.030
regulation of cellular ketone metabolic process GO:0010565 7 0.030
atp catabolic process GO:0006200 4 0.030
brain development GO:0007420 293 0.029
regulation of cell differentiation GO:0045595 142 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.029
positive regulation of cellular amine metabolic process GO:0033240 0 0.029
cellular carbohydrate metabolic process GO:0044262 4 0.029
carboxylic acid biosynthetic process GO:0046394 12 0.028
nucleic acid templated transcription GO:0097659 181 0.028
Mouse
cellular protein modification process GO:0006464 100 0.028
positive regulation of catabolic process GO:0009896 4 0.028
negative regulation of apoptotic signaling pathway GO:2001234 10 0.027
carbohydrate metabolic process GO:0005975 12 0.027
digestive system development GO:0055123 289 0.027
regulation of nucleic acid templated transcription GO:1903506 213 0.027
Mouse
multicellular organism growth GO:0035264 4 0.026
urogenital system development GO:0001655 97 0.026
apoptotic signaling pathway GO:0097190 23 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
lipid metabolic process GO:0006629 52 0.026
regulation of hormone levels GO:0010817 21 0.025
c21 steroid hormone metabolic process GO:0008207 1 0.025
growth GO:0040007 174 0.025
steroid hormone secretion GO:0035929 1 0.025
respiratory electron transport chain GO:0022904 2 0.025
regulation of protein catabolic process GO:0042176 1 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
positive regulation of metabolic process GO:0009893 108 0.025
Mouse
organic acid catabolic process GO:0016054 3 0.025
wound healing GO:0042060 90 0.025
tissue remodeling GO:0048771 4 0.024
cellular component biogenesis GO:0044085 178 0.024
regulation of intracellular signal transduction GO:1902531 57 0.024
development of primary female sexual characteristics GO:0046545 4 0.024
system process GO:0003008 185 0.024
androgen biosynthetic process GO:0006702 1 0.024
macromolecule modification GO:0043412 111 0.023
hormone transport GO:0009914 2 0.023
regulation of transport GO:0051049 45 0.023
positive regulation of biosynthetic process GO:0009891 68 0.023
Mouse
organic substance catabolic process GO:1901575 28 0.023
regulation of cellular protein metabolic process GO:0032268 52 0.022
autophagy GO:0006914 4 0.022
innate immune response GO:0045087 13 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
Mouse
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.022
odontogenesis of dentin containing tooth GO:0042475 1 0.022
regulation of response to cytokine stimulus GO:0060759 3 0.022
regulation of endocrine process GO:0044060 2 0.022
negative regulation of secretion GO:0051048 2 0.022
maintenance of location GO:0051235 4 0.022
cation transport GO:0006812 81 0.021
rna localization GO:0006403 4 0.021
protein homooligomerization GO:0051260 3 0.021
macromolecular complex subunit organization GO:0043933 74 0.021
single organism carbohydrate metabolic process GO:0044723 12 0.021
regulation of erk1 and erk2 cascade GO:0070372 4 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.021
protein secretion GO:0009306 1 0.021
positive regulation of inflammatory response GO:0050729 1 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
cellular response to organic substance GO:0071310 105 0.021
cell cell signaling GO:0007267 52 0.020
cellular response to molecule of bacterial origin GO:0071219 3 0.020
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.020
central nervous system development GO:0007417 387 0.020
amine metabolic process GO:0009308 2 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.020
response to oxygen containing compound GO:1901700 55 0.019
mitochondrial transport GO:0006839 2 0.019
response to carbohydrate GO:0009743 3 0.019
response to lipid GO:0033993 60 0.019
positive regulation of cellular biosynthetic process GO:0031328 68 0.019
Mouse
regulation of intracellular protein transport GO:0033157 3 0.019
very long chain fatty acid biosynthetic process GO:0042761 4 0.019
nuclear export GO:0051168 1 0.019
response to hormone GO:0009725 48 0.019
positive regulation of response to stimulus GO:0048584 80 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
establishment of synaptic vesicle localization GO:0097480 1 0.019
regulation of protein complex assembly GO:0043254 3 0.019
single organism organelle organization GO:1902589 199 0.019
regulation of localization GO:0032879 104 0.019
stem cell maintenance GO:0019827 4 0.018
regulation of rna metabolic process GO:0051252 224 0.018
Mouse
erythrocyte differentiation GO:0030218 54 0.018
digestive tract morphogenesis GO:0048546 231 0.018
cellular response to toxic substance GO:0097237 1 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of cytokine production GO:0001817 3 0.018
positive regulation of signal transduction GO:0009967 56 0.018
regulation of catalytic activity GO:0050790 55 0.018
tube morphogenesis GO:0035239 349 0.017
response to monosaccharide GO:0034284 3 0.017
negative regulation of cell communication GO:0010648 96 0.017
vesicle localization GO:0051648 27 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
neurotransmitter transport GO:0006836 2 0.017
response to cadmium ion GO:0046686 14 0.017
monocarboxylic acid catabolic process GO:0072329 3 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
Mouse
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
regulation of mitochondrion organization GO:0010821 1 0.017
homeostatic process GO:0042592 142 0.016
positive regulation of cell communication GO:0010647 56 0.016
response to external biotic stimulus GO:0043207 97 0.016
multi organism process GO:0051704 134 0.016
regulation of cell proliferation GO:0042127 37 0.016
generation of precursor metabolites and energy GO:0006091 5 0.016
regulation of gtpase activity GO:0043087 2 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
ribonucleotide metabolic process GO:0009259 27 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
regulation of homeostatic process GO:0032844 9 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
rhythmic process GO:0048511 21 0.015
response to wounding GO:0009611 116 0.015
regulation of tissue remodeling GO:0034103 2 0.015
negative regulation of metabolic process GO:0009892 86 0.015
cellular response to external stimulus GO:0071496 2 0.015
response to glucose GO:0009749 3 0.015
protein stabilization GO:0050821 2 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
positive regulation of cytokine production GO:0001819 2 0.015
positive regulation of signaling GO:0023056 56 0.015
response to hydrogen peroxide GO:0042542 3 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
cellular response to drug GO:0035690 1 0.014
developmental growth GO:0048589 166 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
erythrocyte homeostasis GO:0034101 55 0.014
positive regulation of secretion GO:0051047 1 0.014
regulation of apoptotic process GO:0042981 98 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
Mouse
carboxylic acid catabolic process GO:0046395 3 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
Mouse
liver development GO:0001889 96 0.014
organic hydroxy compound metabolic process GO:1901615 16 0.014
regulation of protein binding GO:0043393 3 0.014
leukocyte proliferation GO:0070661 1 0.014
muscle cell differentiation GO:0042692 139 0.014
regulation of tube size GO:0035150 2 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
response to vitamin GO:0033273 3 0.013
sensory perception of pain GO:0019233 1 0.013
positive regulation of myeloid cell differentiation GO:0045639 2 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
Mouse
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.013
negative regulation of catabolic process GO:0009895 3 0.013
cellular response to oxygen levels GO:0071453 1 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
energy derivation by oxidation of organic compounds GO:0015980 5 0.013
organelle transport along microtubule GO:0072384 1 0.013
response to hexose GO:0009746 3 0.013
response to steroid hormone GO:0048545 35 0.013
nitric oxide metabolic process GO:0046209 2 0.013
alpha amino acid metabolic process GO:1901605 3 0.013
positive regulation of apoptotic process GO:0043065 29 0.013
phosphorylation GO:0016310 69 0.013
positive regulation of cell division GO:0051781 2 0.013
oocyte maturation GO:0001556 4 0.013
olfactory lobe development GO:0021988 4 0.013
regulation of programmed cell death GO:0043067 101 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
cellular response to oxygen containing compound GO:1901701 20 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
regulation of hormone metabolic process GO:0032350 6 0.012
protein modification process GO:0036211 100 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
regulation of molecular function GO:0065009 70 0.012
intracellular estrogen receptor signaling pathway GO:0030520 3 0.012
small molecule biosynthetic process GO:0044283 16 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
regulation of immune system process GO:0002682 34 0.012
striated muscle cell development GO:0055002 108 0.012
striated muscle cell differentiation GO:0051146 129 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
gtp catabolic process GO:0006184 2 0.012
regeneration GO:0031099 91 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
meiosis ii GO:0007135 1 0.012
cellular response to oxygen radical GO:0071450 2 0.012
long chain fatty acid biosynthetic process GO:0042759 1 0.012
regulation of protein polymerization GO:0032271 2 0.012
negative regulation of mapk cascade GO:0043409 4 0.011
oxidative phosphorylation GO:0006119 1 0.011
immunoglobulin production GO:0002377 1 0.011
cellular response to hormone stimulus GO:0032870 39 0.011
catabolic process GO:0009056 32 0.011
catechol containing compound metabolic process GO:0009712 2 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
regulation of protein targeting GO:1903533 2 0.011
response to abiotic stimulus GO:0009628 122 0.011
positive regulation of cell cycle GO:0045787 3 0.011
protein metabolic process GO:0019538 183 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
cellular amide metabolic process GO:0043603 4 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
fatty acid elongation GO:0030497 1 0.011
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
regulation of lipid transport GO:0032368 4 0.011
negative regulation of signal transduction GO:0009968 94 0.011
mitochondrial electron transport nadh to ubiquinone GO:0006120 1 0.011
regulation of protein transport GO:0051223 3 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
Mouse
negative regulation of cytoplasmic transport GO:1903650 2 0.011
generation of neurons GO:0048699 385 0.011
hepaticobiliary system development GO:0061008 98 0.010
microtubule based process GO:0007017 60 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
regulation of cellular response to stress GO:0080135 20 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
exocrine pancreas development GO:0031017 28 0.010
phosphatidylinositol mediated signaling GO:0048015 2 0.010
positive regulation of lipid metabolic process GO:0045834 1 0.010
response to endogenous stimulus GO:0009719 83 0.010
cellular response to lipid GO:0071396 39 0.010
nitric oxide biosynthetic process GO:0006809 2 0.010
er nucleus signaling pathway GO:0006984 2 0.010
mononuclear cell proliferation GO:0032943 1 0.010
lipid biosynthetic process GO:0008610 22 0.010
regulation of lipid catabolic process GO:0050994 2 0.010

ptgesl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.108
inherited metabolic disorder DOID:655 0 0.108
disease of anatomical entity DOID:7 0 0.086
nervous system disease DOID:863 0 0.021