Danio rerio

14 known processes

ptgs2a

prostaglandin-endoperoxide synthase 2a

(Aliases: ptgs2,fj02a10,wu:fj02a10,zCOX-2,unp1239)

ptgs2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tube morphogenesis GO:0035239 349 0.903
response to chemical GO:0042221 320 0.883
digestive tract morphogenesis GO:0048546 231 0.879
digestive tract development GO:0048565 265 0.861
signal transduction GO:0007165 455 0.830
Rat
sensory organ development GO:0007423 393 0.807
digestive system development GO:0055123 289 0.786
gastrulation GO:0007369 208 0.751
single organism transport GO:0044765 206 0.698
Rat
negative regulation of response to stimulus GO:0048585 104 0.693
negative regulation of cellular process GO:0048523 283 0.690
Rat
cellular biosynthetic process GO:0044249 286 0.687
Human Mouse Rat
negative regulation of biological process GO:0048519 304 0.668
Rat
regulation of gene expression GO:0010468 265 0.615
gland development GO:0048732 143 0.590
response to vitamin GO:0033273 3 0.585
Rat
response to corticosteroid GO:0031960 1 0.562
Rat
response to transition metal nanoparticle GO:1990267 28 0.548
Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.535
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.504
brain development GO:0007420 293 0.498
response to lipid GO:0033993 60 0.473
Rat
nucleobase containing compound biosynthetic process GO:0034654 205 0.451
regulation of developmental process GO:0050793 247 0.437
Mouse Rat
organic substance biosynthetic process GO:1901576 289 0.402
Human Mouse Rat
death GO:0016265 121 0.392
Rat
cell motility GO:0048870 244 0.387
Rat
regulation of primary metabolic process GO:0080090 311 0.386
nitrogen compound metabolic process GO:0006807 319 0.386
Rat
mitochondrion organization GO:0007005 4 0.386
fatty acid biosynthetic process GO:0006633 4 0.384
Human Mouse Rat
response to organic substance GO:0010033 153 0.383
gene expression GO:0010467 252 0.382
cognition GO:0050890 1 0.376
Rat
macromolecule biosynthetic process GO:0009059 227 0.371
regulation of biological quality GO:0065008 263 0.363
Mouse Rat
biosynthetic process GO:0009058 294 0.359
Human Mouse Rat
transcription from rna polymerase ii promoter GO:0006366 80 0.357
regulation of multicellular organismal process GO:0051239 277 0.350
Mouse Rat
regulation of response to stimulus GO:0048583 269 0.347
Mouse Rat
cellular response to organic cyclic compound GO:0071407 38 0.344
small molecule metabolic process GO:0044281 77 0.342
Human Mouse Rat
response to glucocorticoid GO:0051384 1 0.340
Rat
rna metabolic process GO:0016070 219 0.337
lateral line development GO:0048882 66 0.327
cellular nitrogen compound biosynthetic process GO:0044271 218 0.325
Rat
signal transduction in absence of ligand GO:0038034 1 0.314
protein metabolic process GO:0019538 183 0.314
nucleobase containing compound metabolic process GO:0006139 274 0.310
positive regulation of response to external stimulus GO:0032103 9 0.305
Mouse Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.298
establishment of endothelial barrier GO:0061028 3 0.296
multi organism process GO:0051704 134 0.295
Mouse Rat
nucleic acid metabolic process GO:0090304 244 0.295
immune system development GO:0002520 191 0.292
regulation of cellular metabolic process GO:0031323 320 0.291
Rat
negative regulation of gene expression GO:0010629 65 0.286
regulation of muscle contraction GO:0006937 3 0.284
Rat
cellular macromolecule metabolic process GO:0044260 391 0.282
cell surface receptor signaling pathway GO:0007166 325 0.281
cellular nitrogen compound metabolic process GO:0034641 290 0.281
Rat
appendage development GO:0048736 80 0.278
response to oxygen containing compound GO:1901700 55 0.276
Rat
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.272
positive regulation of metabolic process GO:0009893 108 0.272
Rat
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.270
regulation of protein import into nucleus GO:0042306 2 0.270
Rat
female sex differentiation GO:0046660 4 0.266
regulation of response to oxidative stress GO:1902882 2 0.266
lipid metabolic process GO:0006629 52 0.265
Human Mouse Rat
regulation of protein transport GO:0051223 3 0.265
Rat
regulation of epithelial cell proliferation GO:0050678 3 0.265
regulation of cell death GO:0010941 103 0.264
Rat
positive regulation of blood circulation GO:1903524 2 0.261
Rat
regulation of nitrogen compound metabolic process GO:0051171 251 0.255
Rat
locomotion GO:0040011 313 0.251
Rat
reproduction GO:0000003 40 0.250
Mouse Rat
cellular aromatic compound metabolic process GO:0006725 295 0.250
intrinsic apoptotic signaling pathway GO:0097193 20 0.249
response to bacterium GO:0009617 58 0.248
Rat
ion transport GO:0006811 114 0.240
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.236
Rat
cellular response to chemical stimulus GO:0070887 157 0.235
cell cycle g1 s phase transition GO:0044843 1 0.234
organic cyclic compound metabolic process GO:1901360 301 0.233
long chain fatty acid transport GO:0015909 1 0.231
extrinsic apoptotic signaling pathway GO:0097191 3 0.227
response to external stimulus GO:0009605 264 0.225
Mouse Rat
single organism metabolic process GO:0044710 217 0.222
hematopoietic or lymphoid organ development GO:0048534 191 0.221
regulation of cellular biosynthetic process GO:0031326 245 0.220
Rat
positive regulation of neuron death GO:1901216 1 0.219
response to ketone GO:1901654 1 0.216
regulation of localization GO:0032879 104 0.216
Rat
regulation of rna metabolic process GO:0051252 224 0.215
epithelial cell differentiation GO:0030855 116 0.214
larval development GO:0002164 2 0.214
cellular response to endogenous stimulus GO:0071495 68 0.212
Rat
regulation of biosynthetic process GO:0009889 250 0.212
Rat
single organism biosynthetic process GO:0044711 71 0.205
Human Mouse Rat
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.205
cellular response to starvation GO:0009267 1 0.204
aging GO:0007568 2 0.199
regulation of cell cycle GO:0051726 52 0.189
Rat
regulation of macromolecule metabolic process GO:0060255 317 0.188
positive regulation of macromolecule metabolic process GO:0010604 93 0.187
programmed cell death GO:0012501 119 0.185
Rat
embryonic organ development GO:0048568 381 0.182
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.179
regulation of establishment of protein localization GO:0070201 4 0.178
Rat
regulation of cell communication GO:0010646 232 0.178
Rat
response to alcohol GO:0097305 14 0.178
Rat
multicellular organism growth GO:0035264 4 0.176
nuclear transport GO:0051169 4 0.174
Rat
response to nutrient GO:0007584 3 0.172
Rat
female gonad development GO:0008585 4 0.172
apoptotic process GO:0006915 116 0.171
Rat
nuclear import GO:0051170 3 0.171
Rat
cell death GO:0008219 121 0.169
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.168
single organism reproductive process GO:0044702 40 0.167
Mouse Rat
negative regulation of secretion by cell GO:1903531 2 0.167
regulation of protein localization to nucleus GO:1900180 2 0.165
Rat
regulation of metabolic process GO:0019222 359 0.165
Rat
neuron differentiation GO:0030182 353 0.161
response to stress GO:0006950 263 0.160
Human Mouse Rat
generation of neurons GO:0048699 385 0.159
response to organic cyclic compound GO:0014070 51 0.159
heterocycle metabolic process GO:0046483 290 0.155
central nervous system development GO:0007417 387 0.155
cellular response to oxygen levels GO:0071453 1 0.155
Human
apoptotic signaling pathway GO:0097190 23 0.153
epithelial cell development GO:0002064 42 0.153
regulation of cell proliferation GO:0042127 37 0.153
Mouse Rat
regulation of sodium ion transport GO:0002028 2 0.152
vasculature development GO:0001944 278 0.149
Zebrafish Rat
nucleic acid templated transcription GO:0097659 181 0.147
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.146
head development GO:0060322 303 0.146
multicellular organism reproduction GO:0032504 35 0.146
Mouse Rat
negative regulation of multicellular organismal process GO:0051241 69 0.142
Rat
cellular response to nutrient levels GO:0031669 2 0.140
regulation of anatomical structure morphogenesis GO:0022603 130 0.136
Rat
response to hormone GO:0009725 48 0.136
Rat
regulation of rna biosynthetic process GO:2001141 213 0.136
negative regulation of signaling GO:0023057 96 0.135
Rat
positive regulation of epithelial cell migration GO:0010634 2 0.134
Rat
response to external biotic stimulus GO:0043207 97 0.133
Rat
establishment of protein localization to organelle GO:0072594 4 0.131
Rat
negative regulation of protein transport GO:0051224 3 0.131
regulation of oxidative stress induced cell death GO:1903201 2 0.129
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.128
morphogenesis of an epithelium GO:0002009 333 0.127
lipid biosynthetic process GO:0008610 22 0.127
Human Mouse Rat
response to endogenous stimulus GO:0009719 83 0.126
Rat
positive regulation of neuron apoptotic process GO:0043525 1 0.126
response to steroid hormone GO:0048545 35 0.126
Rat
negative regulation of programmed cell death GO:0043069 58 0.125
transcription dna templated GO:0006351 181 0.124
regulation of binding GO:0051098 3 0.123
immune system process GO:0002376 241 0.123
multicellular organismal reproductive process GO:0048609 35 0.123
Mouse Rat
negative regulation of hormone secretion GO:0046888 2 0.123
negative regulation of signal transduction GO:0009968 94 0.123
cellular component movement GO:0006928 335 0.122
Rat
single organism nuclear import GO:1902593 3 0.122
Rat
lipid digestion GO:0044241 3 0.117
regulation of intracellular protein transport GO:0033157 3 0.117
Rat
positive regulation of cellular metabolic process GO:0031325 94 0.116
Rat
negative regulation of cellular metabolic process GO:0031324 77 0.115
regulation of metal ion transport GO:0010959 4 0.114
Rat
cellular response to external stimulus GO:0071496 2 0.114
Rat
regeneration GO:0031099 91 0.114
organic cyclic compound biosynthetic process GO:1901362 223 0.114
fin morphogenesis GO:0033334 53 0.114
negative regulation of cell proliferation GO:0008285 8 0.113
Rat
single organism localization GO:1902578 225 0.113
Rat
positive regulation of cellular catabolic process GO:0031331 3 0.112
cell cycle GO:0007049 93 0.112
Rat
mesenchyme development GO:0060485 127 0.111
regulation of tube size GO:0035150 2 0.111
Rat
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.111
cellular response to hormone stimulus GO:0032870 39 0.110
neurological system process GO:0050877 62 0.110
Rat
nucleocytoplasmic transport GO:0006913 4 0.110
Rat
intracellular receptor signaling pathway GO:0030522 30 0.110
protein import GO:0017038 3 0.110
Rat
fatty acid transport GO:0015908 1 0.110
cell death in response to oxidative stress GO:0036473 2 0.108
cell cell adhesion GO:0098609 6 0.107
single organism organelle organization GO:1902589 199 0.106
mitotic cell cycle process GO:1903047 48 0.104
regulation of apoptotic process GO:0042981 98 0.104
Rat
aromatic compound biosynthetic process GO:0019438 217 0.104
biological adhesion GO:0022610 40 0.103
collagen metabolic process GO:0032963 2 0.103
camera type eye development GO:0043010 222 0.103
epiboly GO:0090504 41 0.103
endocrine system development GO:0035270 65 0.103
neuromast development GO:0048884 46 0.102
positive regulation of cellular process GO:0048522 201 0.102
Mouse Rat
positive regulation of biosynthetic process GO:0009891 68 0.102
Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.101
response to fatty acid GO:0070542 5 0.101
Rat
regulation of cytoplasmic transport GO:1903649 4 0.101
Rat
blood vessel development GO:0001568 246 0.101
Zebrafish Rat
hindbrain development GO:0030902 91 0.101
formation of primary germ layer GO:0001704 62 0.100
heterocycle biosynthetic process GO:0018130 215 0.100
gastrulation with mouth forming second GO:0001702 44 0.100
regulation of wound healing GO:0061041 2 0.100
cell migration GO:0016477 237 0.099
Rat
positive regulation of catabolic process GO:0009896 4 0.098
positive regulation of gene expression GO:0010628 71 0.098
growth GO:0040007 174 0.097
cellular macromolecule biosynthetic process GO:0034645 224 0.097
chordate embryonic development GO:0043009 271 0.095
regulation of phosphate metabolic process GO:0019220 43 0.094
embryo development ending in birth or egg hatching GO:0009792 271 0.094
odontogenesis of dentin containing tooth GO:0042475 1 0.092
sensory system development GO:0048880 76 0.091
endothelium development GO:0003158 25 0.091
endothelial cell development GO:0001885 12 0.091
positive regulation of cellular biosynthetic process GO:0031328 68 0.090
Rat
g1 s transition of mitotic cell cycle GO:0000082 1 0.090
regulation of cell differentiation GO:0045595 142 0.090
Mouse
multicellular organismal metabolic process GO:0044236 2 0.089
regulation of multicellular organismal development GO:2000026 223 0.089
Rat
regulation of nucleotide catabolic process GO:0030811 2 0.089
positive regulation of epithelial cell proliferation GO:0050679 1 0.089
negative regulation of secretion GO:0051048 2 0.088
renal system development GO:0072001 94 0.087
Zebrafish
keratinocyte differentiation GO:0030216 0 0.087
apoptotic process involved in development GO:1902742 2 0.086
sexual reproduction GO:0019953 36 0.086
Rat
endodermal cell fate determination GO:0007493 2 0.086
morphogenesis of an epithelial sheet GO:0002011 49 0.085
somitogenesis GO:0001756 87 0.085
mitotic cell cycle GO:0000278 64 0.085
ear development GO:0043583 127 0.084
multi organism reproductive process GO:0044703 36 0.083
Mouse Rat
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.082
regulation of purine nucleotide catabolic process GO:0033121 2 0.082
protein import into nucleus GO:0006606 3 0.082
Rat
behavior GO:0007610 74 0.081
Rat
skeletal system development GO:0001501 181 0.081
cell proliferation GO:0008283 80 0.080
Mouse Rat
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.080
ovarian follicle development GO:0001541 2 0.080
negative regulation of cell communication GO:0010648 96 0.080
Rat
system process GO:0003008 185 0.079
Mouse Rat
ear morphogenesis GO:0042471 64 0.079
desmosome organization GO:0002934 3 0.079
cellular response to organic substance GO:0071310 105 0.079
cellular component biogenesis GO:0044085 178 0.079
monocarboxylic acid biosynthetic process GO:0072330 12 0.079
Human Mouse Rat
positive regulation of rna biosynthetic process GO:1902680 57 0.079
negative regulation of macromolecule metabolic process GO:0010605 76 0.079
ossification GO:0001503 23 0.078
Rat
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.078
regionalization GO:0003002 274 0.078
positive regulation of transport GO:0051050 2 0.078
Rat
cellular component assembly GO:0022607 170 0.078
carbohydrate derivative biosynthetic process GO:1901137 43 0.077
carbohydrate derivative metabolic process GO:1901135 61 0.076
long chain fatty acid metabolic process GO:0001676 1 0.075
Human Mouse
positive regulation of gtp catabolic process GO:0033126 1 0.075
cellular response to lipopolysaccharide GO:0071222 3 0.074
phagocytosis GO:0006909 3 0.074
diencephalon development GO:0021536 58 0.074
ectodermal cell fate specification GO:0001715 2 0.073
endocrine process GO:0050886 2 0.072
negative regulation of biosynthetic process GO:0009890 55 0.072
mesoderm morphogenesis GO:0048332 51 0.070
single organism behavior GO:0044708 24 0.070
Rat
response to wounding GO:0009611 116 0.069
Mouse Rat
insulin like growth factor receptor signaling pathway GO:0048009 4 0.069
reciprocal dna recombination GO:0035825 1 0.069
response to abiotic stimulus GO:0009628 122 0.069
Human Rat
regulation of endothelial cell proliferation GO:0001936 1 0.068
positive regulation of cell differentiation GO:0045597 30 0.068
Mouse
neural crest cell development GO:0014032 62 0.068
organic acid metabolic process GO:0006082 31 0.068
Human Mouse Rat
organelle organization GO:0006996 227 0.068
regulation of autophagy GO:0010506 3 0.068
cellular response to lipid GO:0071396 39 0.067
regulation of programmed cell death GO:0043067 101 0.067
Rat
fin development GO:0033333 77 0.066
intestinal absorption GO:0050892 2 0.066
localization of cell GO:0051674 244 0.066
Rat
positive regulation of gtpase activity GO:0043547 1 0.065
pronephros development GO:0048793 69 0.064
protein secretion GO:0009306 1 0.064
lateral line system development GO:0048925 76 0.064
negative regulation of apoptotic process GO:0043066 55 0.064
neuron death GO:0070997 21 0.063
establishment of localization GO:0051234 244 0.063
Rat
rna biosynthetic process GO:0032774 181 0.063
cellular protein metabolic process GO:0044267 129 0.063
negative regulation of intracellular signal transduction GO:1902532 22 0.063
response to monosaccharide GO:0034284 3 0.063
Rat
defense response GO:0006952 47 0.062
Mouse Rat
organonitrogen compound metabolic process GO:1901564 74 0.062
negative regulation of mitosis GO:0045839 3 0.062
positive regulation of apoptotic signaling pathway GO:2001235 1 0.061
cellular localization GO:0051641 97 0.060
Rat
cell growth GO:0016049 57 0.060
response to drug GO:0042493 3 0.060
Rat
negative regulation of metabolic process GO:0009892 86 0.060
cell cycle process GO:0022402 53 0.060
positive regulation of developmental process GO:0051094 50 0.059
Mouse Rat
regulation of apoptotic signaling pathway GO:2001233 12 0.059
negative regulation of cellular biosynthetic process GO:0031327 55 0.059
regulation of macromolecule biosynthetic process GO:0010556 225 0.058
gtp catabolic process GO:0006184 2 0.058
endothelial cell differentiation GO:0045446 20 0.058
reactive oxygen species biosynthetic process GO:1903409 1 0.058
reactive nitrogen species metabolic process GO:2001057 0 0.057
wnt signaling pathway GO:0016055 80 0.057
regulation of blood vessel size GO:0050880 2 0.057
Rat
regulation of protein targeting GO:1903533 2 0.056
Rat
negative regulation of nuclear division GO:0051784 3 0.056
heart development GO:0007507 313 0.056
cell adhesion GO:0007155 40 0.055
macromolecule modification GO:0043412 111 0.054
positive regulation of nucleoside metabolic process GO:0045979 1 0.054
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.054
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.054
regulation of gtp catabolic process GO:0033124 2 0.054
respiratory system development GO:0060541 5 0.054
regulation of reactive oxygen species metabolic process GO:2000377 2 0.053
multicellular organismal macromolecule metabolic process GO:0044259 2 0.053
phosphorus metabolic process GO:0006793 109 0.052
positive regulation of transcription dna templated GO:0045893 57 0.052
positive regulation of rna metabolic process GO:0051254 59 0.052
regulation of signal transduction GO:0009966 225 0.052
Rat
osteoclast differentiation GO:0030316 1 0.052
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.051
positive regulation of nucleic acid templated transcription GO:1903508 57 0.051
reciprocal meiotic recombination GO:0007131 1 0.051
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.050
regulation of mitochondrion organization GO:0010821 1 0.050
cell fate commitment GO:0045165 99 0.050
positive regulation of biological process GO:0048518 253 0.049
Mouse Rat
bmp signaling pathway GO:0030509 52 0.049
neuron projection guidance GO:0097485 86 0.049
forebrain development GO:0030900 96 0.048
guanosine containing compound catabolic process GO:1901069 2 0.048
response to biotic stimulus GO:0009607 97 0.048
Rat
amine metabolic process GO:0009308 2 0.048
thyroid gland development GO:0030878 12 0.047
establishment of localization in cell GO:0051649 77 0.047
Rat
morphogenesis of a branching structure GO:0001763 21 0.047
gamete generation GO:0007276 33 0.047
Rat
tissue regeneration GO:0042246 74 0.046
regulation of cytokine production GO:0001817 3 0.046
Rat
regulation of phosphorus metabolic process GO:0051174 43 0.046
regulation of cellular amine metabolic process GO:0033238 0 0.046
regulation of protein complex assembly GO:0043254 3 0.046
vasculogenesis GO:0001570 41 0.045
Zebrafish
regulation of blood pressure GO:0008217 1 0.045
Mouse
reproductive process GO:0022414 40 0.045
Mouse Rat
liver development GO:0001889 96 0.045
negative regulation of epithelial cell proliferation GO:0050680 1 0.045
regulation of inflammatory response GO:0050727 2 0.045
Mouse Rat
steroid hormone secretion GO:0035929 1 0.044
carboxylic acid metabolic process GO:0019752 22 0.044
Human Mouse Rat
regulation of cellular component organization GO:0051128 86 0.044
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.044
regulation of protein metabolic process GO:0051246 56 0.044
endoderm formation GO:0001706 29 0.044
positive regulation of myeloid cell differentiation GO:0045639 2 0.044
response to carbohydrate GO:0009743 3 0.044
Rat
positive regulation of cell cycle GO:0045787 3 0.043
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.043
kidney development GO:0001822 92 0.043
Zebrafish
protein targeting to nucleus GO:0044744 3 0.043
Rat
protein localization to nucleus GO:0034504 3 0.043
Rat
myeloid cell homeostasis GO:0002262 56 0.043
enzyme linked receptor protein signaling pathway GO:0007167 106 0.043
urea transport GO:0015840 11 0.043
regulation of cellular response to oxidative stress GO:1900407 2 0.042
response to nitrogen compound GO:1901698 19 0.042
Rat
positive regulation of nucleotide catabolic process GO:0030813 1 0.042
regulation of neural precursor cell proliferation GO:2000177 3 0.042
endocrine hormone secretion GO:0060986 2 0.042
cell part morphogenesis GO:0032990 246 0.042
protein modification process GO:0036211 100 0.042
blood vessel morphogenesis GO:0048514 216 0.042
Zebrafish Rat
cellular response to prostaglandin stimulus GO:0071379 3 0.042
negative regulation of transcription dna templated GO:0045892 45 0.042
gtp metabolic process GO:0046039 4 0.041
transport GO:0006810 220 0.041
Rat
regulation of signaling GO:0023051 235 0.041
Rat
negative regulation of feeding behavior GO:2000252 2 0.041
phagocytosis engulfment GO:0006911 1 0.041
meiosis i GO:0007127 1 0.041
eye development GO:0001654 277 0.041
regulation of chronic inflammatory response GO:0002676 1 0.041
cell projection organization GO:0030030 284 0.041
regulation of gonadotropin secretion GO:0032276 1 0.040
regulation of dna templated transcription in response to stress GO:0043620 0 0.040
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 6 0.040
positive regulation of response to stimulus GO:0048584 80 0.039
Mouse Rat
chemotaxis GO:0006935 104 0.039
regulation of transport GO:0051049 45 0.039
Rat
dorsal ventral pattern formation GO:0009953 125 0.039
hormone secretion GO:0046879 2 0.039
fin regeneration GO:0031101 51 0.039
regulation of nucleoside metabolic process GO:0009118 2 0.039
regulation of intracellular signal transduction GO:1902531 57 0.039
Rat
negative regulation of cell fate specification GO:0009996 11 0.039
developmental growth GO:0048589 166 0.038
cell migration involved in gastrulation GO:0042074 79 0.038
wound healing GO:0042060 90 0.038
erk1 and erk2 cascade GO:0070371 4 0.038
negative regulation of rna metabolic process GO:0051253 48 0.038
maintenance of location GO:0051235 4 0.038
regulation of dna replication GO:0006275 3 0.038
positive regulation of protein metabolic process GO:0051247 23 0.037
regulation of reproductive process GO:2000241 4 0.037
regulation of nervous system development GO:0051960 90 0.037
rhythmic process GO:0048511 21 0.037
cellular response to oxygen containing compound GO:1901701 20 0.036
Rat
neuron development GO:0048666 262 0.036
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.036
myeloid cell differentiation GO:0030099 86 0.036
cellular response to extracellular stimulus GO:0031668 2 0.036
cellular carbohydrate metabolic process GO:0044262 4 0.036
angiogenesis GO:0001525 158 0.036
Rat
nucleoside phosphate metabolic process GO:0006753 28 0.036
negative regulation of defense response GO:0031348 2 0.036
inner ear development GO:0048839 126 0.036
homeostatic process GO:0042592 142 0.035
Mouse Rat
sympathetic nervous system development GO:0048485 3 0.035
regulation of hormone secretion GO:0046883 2 0.035
regulation of embryonic development GO:0045995 47 0.035
response to acid chemical GO:0001101 17 0.035
Rat
regulation of chondrocyte differentiation GO:0032330 1 0.035
cellular protein modification process GO:0006464 100 0.035
heart morphogenesis GO:0003007 156 0.035
negative regulation of nucleic acid templated transcription GO:1903507 45 0.035
water homeostasis GO:0030104 4 0.035
response to amino acid GO:0043200 2 0.034
regulation of catenin import into nucleus GO:0035412 2 0.034
regulation of nucleocytoplasmic transport GO:0046822 2 0.034
Rat
intracellular signal transduction GO:0035556 85 0.034
Rat
regulation of catalytic activity GO:0050790 55 0.034
response to glucose GO:0009749 3 0.034
protein localization GO:0008104 40 0.034
Rat
connective tissue development GO:0061448 99 0.033
regulation of mesenchymal cell proliferation GO:0010464 1 0.033
development of primary female sexual characteristics GO:0046545 4 0.033
ovulation cycle GO:0042698 2 0.033
regulation of neurogenesis GO:0050767 87 0.032
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.032
tissue remodeling GO:0048771 4 0.032
mesoderm development GO:0007498 88 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
negative regulation of cell cycle GO:0045786 14 0.032
Rat
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.032
zymogen activation GO:0031638 3 0.032
glial cell migration GO:0008347 3 0.032
cellular response to steroid hormone stimulus GO:0071383 31 0.032
epidermis development GO:0008544 48 0.032
Mouse
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.032
axonogenesis GO:0007409 152 0.031
oxoacid metabolic process GO:0043436 31 0.031
Human Mouse Rat
regulation of multicellular organism growth GO:0040014 4 0.031
regulation of cell growth GO:0001558 29 0.031
oocyte maturation GO:0001556 4 0.031
carboxylic acid biosynthetic process GO:0046394 12 0.031
Human Mouse Rat
sensory organ morphogenesis GO:0090596 200 0.031
response to hexose GO:0009746 3 0.031
Rat
negative regulation of developmental process GO:0051093 65 0.031
response to oxygen levels GO:0070482 25 0.031
Human
reactive oxygen species metabolic process GO:0072593 6 0.031
protein acetylation GO:0006473 2 0.031
smooth muscle contraction GO:0006939 2 0.031
Rat
regulation of transcription dna templated GO:0006355 213 0.031
negative regulation of intracellular transport GO:0032387 3 0.031
regulation of response to cytokine stimulus GO:0060759 3 0.030
positive regulation of stem cell proliferation GO:2000648 1 0.030
ectoderm formation GO:0001705 2 0.030
ovulation cycle process GO:0022602 2 0.029
embryonic skeletal system morphogenesis GO:0048704 93 0.029

ptgs2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.050
cancer DOID:162 0 0.050
disease of cellular proliferation DOID:14566 0 0.050
organ system cancer DOID:0050686 0 0.050
colon carcinoma DOID:1520 0 0.034
large intestine cancer DOID:5672 0 0.034
colon cancer DOID:219 0 0.034
intestinal cancer DOID:10155 0 0.034
colorectal cancer DOID:9256 0 0.034
disease of anatomical entity DOID:7 0 0.033