Danio rerio

7 known processes

ptpn6

protein tyrosine phosphatase, non-receptor type 6

(Aliases: fj22f05,zgc:55501,wu:fj22f05,SHP1,Hcph)

ptpn6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular extravasation GO:0002693 1 0.993
neutrophil mediated immunity GO:0002446 1 0.661
superoxide metabolic process GO:0006801 2 0.645
response to biotic stimulus GO:0009607 97 0.576
cellular component morphogenesis GO:0032989 336 0.486
regulation of cellular extravasation GO:0002691 1 0.483
cell motility GO:0048870 244 0.441
defense response to other organism GO:0098542 33 0.421
cellular extravasation GO:0045123 1 0.395
cell morphogenesis GO:0000902 289 0.374
response to other organism GO:0051707 97 0.359
neuron development GO:0048666 262 0.342
immune system process GO:0002376 241 0.341
protein polymerization GO:0051258 4 0.341
response to chemical GO:0042221 320 0.337
localization of cell GO:0051674 244 0.321
cell part morphogenesis GO:0032990 246 0.318
response to external stimulus GO:0009605 264 0.314
immune response GO:0006955 28 0.311
positive regulation of apoptotic signaling pathway GO:2001235 1 0.299
gastrulation GO:0007369 208 0.296
cell projection organization GO:0030030 284 0.290
positive regulation of neutrophil extravasation GO:2000391 1 0.270
signal transduction GO:0007165 455 0.267
response to stress GO:0006950 263 0.266
axon development GO:0061564 166 0.266
regulation of primary metabolic process GO:0080090 311 0.264
regulation of multicellular organismal process GO:0051239 277 0.264
neuron projection development GO:0031175 180 0.263
cell projection morphogenesis GO:0048858 244 0.260
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.256
neutrophil migration GO:1990266 10 0.239
defense response GO:0006952 47 0.235
cellular macromolecule metabolic process GO:0044260 391 0.232
generation of neurons GO:0048699 385 0.222
cell migration GO:0016477 237 0.222
leukocyte homeostasis GO:0001776 2 0.209
morphogenesis of an epithelium GO:0002009 333 0.206
angiogenesis GO:0001525 158 0.202
neuron differentiation GO:0030182 353 0.202
cell substrate adhesion GO:0031589 4 0.195
cell surface receptor signaling pathway GO:0007166 325 0.193
single organism metabolic process GO:0044710 217 0.193
tube morphogenesis GO:0035239 349 0.190
regulation of metabolic process GO:0019222 359 0.186
positive regulation of protein polymerization GO:0032273 2 0.182
taxis GO:0042330 109 0.179
cellular component movement GO:0006928 335 0.178
regulation of response to stimulus GO:0048583 269 0.174
tissue regeneration GO:0042246 74 0.172
regulation of multicellular organismal development GO:2000026 223 0.167
regulation of cell activation GO:0050865 1 0.167
regulation of synapse organization GO:0050807 3 0.165
regulation of protein polymerization GO:0032271 2 0.159
positive regulation of biological process GO:0048518 253 0.157
striated muscle cell development GO:0055002 108 0.148
cellular component assembly GO:0022607 170 0.146
regulation of macromolecule metabolic process GO:0060255 317 0.145
immune effector process GO:0002252 23 0.143
muscle structure development GO:0061061 196 0.140
organic acid metabolic process GO:0006082 31 0.138
granulocyte migration GO:0097530 11 0.138
axonogenesis GO:0007409 152 0.133
regulation of signal transduction GO:0009966 225 0.130
digestive tract development GO:0048565 265 0.128
single organism organelle organization GO:1902589 199 0.127
locomotion GO:0040011 313 0.126
actin cytoskeleton organization GO:0030036 63 0.125
regulation of protein complex assembly GO:0043254 3 0.124
sensory organ development GO:0007423 393 0.123
myeloid leukocyte migration GO:0097529 12 0.121
cytoskeleton organization GO:0007010 96 0.119
neutrophil chemotaxis GO:0030593 10 0.119
regulation of cell motility GO:2000145 46 0.116
oxoacid metabolic process GO:0043436 31 0.116
regulation of establishment of protein localization GO:0070201 4 0.114
larval development GO:0002164 2 0.114
regulation of nitrogen compound metabolic process GO:0051171 251 0.113
regulation of immune system process GO:0002682 34 0.112
cell morphogenesis involved in differentiation GO:0000904 195 0.111
cellular amino acid metabolic process GO:0006520 7 0.108
small molecule metabolic process GO:0044281 77 0.106
hematopoietic stem cell migration GO:0035701 4 0.103
cellular nitrogen compound metabolic process GO:0034641 290 0.102
regulation of neutrophil migration GO:1902622 6 0.101
regulation of developmental process GO:0050793 247 0.100
positive regulation of cellular component biogenesis GO:0044089 3 0.099
regulation of signaling GO:0023051 235 0.099
positive regulation of response to stimulus GO:0048584 80 0.097
regulation of cellular component movement GO:0051270 55 0.096
negative regulation of biological process GO:0048519 304 0.095
regulation of cell development GO:0060284 100 0.094
neuron projection morphogenesis GO:0048812 161 0.091
blood vessel morphogenesis GO:0048514 216 0.091
positive regulation of cellular process GO:0048522 201 0.091
multi organism process GO:0051704 134 0.090
organonitrogen compound metabolic process GO:1901564 74 0.086
cellular response to chemical stimulus GO:0070887 157 0.084
heterocycle metabolic process GO:0046483 290 0.082
chemotaxis GO:0006935 104 0.082
regulation of anatomical structure morphogenesis GO:0022603 130 0.081
regulation of cell communication GO:0010646 232 0.080
cellular component biogenesis GO:0044085 178 0.078
g protein coupled receptor signaling pathway GO:0007186 74 0.077
lateral inhibition GO:0046331 1 0.076
organelle fusion GO:0048284 3 0.076
actin filament polymerization GO:0030041 2 0.076
guanosine containing compound catabolic process GO:1901069 2 0.076
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.076
positive regulation of cell activation GO:0050867 1 0.074
regulation of cell differentiation GO:0045595 142 0.074
myotube differentiation GO:0014902 45 0.074
release of sequestered calcium ion into cytosol GO:0051209 3 0.074
reactive oxygen species metabolic process GO:0072593 6 0.073
negative regulation of sequestering of calcium ion GO:0051283 4 0.073
regulation of cell migration GO:0030334 40 0.072
actin polymerization or depolymerization GO:0008154 2 0.072
defense response to fungus GO:0050832 2 0.071
regulation of cellular component organization GO:0051128 86 0.071
regulation of metal ion transport GO:0010959 4 0.070
positive regulation of response to external stimulus GO:0032103 9 0.070
organelle organization GO:0006996 227 0.070
regulation of apoptotic process GO:0042981 98 0.069
sequestering of calcium ion GO:0051208 3 0.069
axonal defasciculation GO:0007414 2 0.069
digestive system development GO:0055123 289 0.069
positive regulation of catabolic process GO:0009896 4 0.068
establishment of localization GO:0051234 244 0.067
response to bacterium GO:0009617 58 0.066
carboxylic acid metabolic process GO:0019752 22 0.065
regulation of localization GO:0032879 104 0.065
single organism membrane fusion GO:0044801 2 0.065
regulation of synapse assembly GO:0051963 3 0.063
cation transport GO:0006812 81 0.063
regulation of cell shape GO:0008360 1 0.063
muscle cell development GO:0055001 115 0.063
maintenance of location GO:0051235 4 0.063
guanosine containing compound metabolic process GO:1901068 4 0.062
leukocyte chemotaxis GO:0030595 12 0.061
nitrogen compound metabolic process GO:0006807 319 0.061
calcium ion transport into cytosol GO:0060402 3 0.060
transport GO:0006810 220 0.060
regulation of nervous system development GO:0051960 90 0.059
leukocyte proliferation GO:0070661 1 0.059
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.059
regulation of sequestering of calcium ion GO:0051282 4 0.058
eye development GO:0001654 277 0.057
homeostatic process GO:0042592 142 0.056
motor neuron axon guidance GO:0008045 23 0.056
retina development in camera type eye GO:0060041 146 0.056
hydrogen peroxide metabolic process GO:0042743 2 0.056
organic substance biosynthetic process GO:1901576 289 0.055
cellular component maintenance GO:0043954 3 0.055
cell projection assembly GO:0030031 64 0.055
organic cyclic compound metabolic process GO:1901360 301 0.053
regulation of locomotion GO:0040012 55 0.052
central nervous system development GO:0007417 387 0.052
developmental growth GO:0048589 166 0.052
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.051
ameboidal type cell migration GO:0001667 143 0.051
leukocyte mediated immunity GO:0002443 6 0.051
regulation of leukocyte migration GO:0002685 8 0.050
response to external biotic stimulus GO:0043207 97 0.050
regulation of cellular amine metabolic process GO:0033238 0 0.050
actin filament based process GO:0030029 64 0.050
regulation of cellular component size GO:0032535 30 0.049
regulation of cell projection organization GO:0031344 44 0.049
negative regulation of protein phosphorylation GO:0001933 4 0.049
embryonic organ morphogenesis GO:0048562 274 0.049
aging GO:0007568 2 0.048
neutrophil extravasation GO:0072672 1 0.048
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.048
positive regulation of protein complex assembly GO:0031334 2 0.048
amine metabolic process GO:0009308 2 0.047
nucleobase containing compound metabolic process GO:0006139 274 0.047
maternal determination of anterior posterior axis embryo GO:0008358 4 0.047
regulation of cellular amino acid metabolic process GO:0006521 0 0.047
positive regulation of metabolic process GO:0009893 108 0.047
regulation of nucleoside metabolic process GO:0009118 2 0.046
sprouting angiogenesis GO:0002040 53 0.046
regulation of dendrite morphogenesis GO:0048814 3 0.046
regulation of biological quality GO:0065008 263 0.046
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.046
organelle assembly GO:0070925 110 0.046
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.046
positive regulation of cell killing GO:0031343 2 0.045
response to wounding GO:0009611 116 0.045
carbohydrate derivative metabolic process GO:1901135 61 0.043
regulation of muscle contraction GO:0006937 3 0.043
cellular ketone metabolic process GO:0042180 11 0.043
lymphangiogenesis GO:0001946 25 0.042
regulation of neutrophil chemotaxis GO:0090022 5 0.042
phagocytosis GO:0006909 3 0.042
camera type eye development GO:0043010 222 0.042
leukocyte migration GO:0050900 15 0.042
multicellular organismal reproductive process GO:0048609 35 0.042
negative regulation of cellular process GO:0048523 283 0.041
defense response to bacterium GO:0042742 22 0.041
single organism localization GO:1902578 225 0.041
lymph vessel morphogenesis GO:0036303 25 0.041
positive regulation of neutrophil migration GO:1902624 0 0.041
adherens junction organization GO:0034332 4 0.040
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.040
negative regulation of synapse assembly GO:0051964 2 0.040
head development GO:0060322 303 0.039
positive regulation of secretion by cell GO:1903532 1 0.039
regulation of transcription dna templated GO:0006355 213 0.039
muscle organ development GO:0007517 101 0.039
homeostasis of number of cells within a tissue GO:0048873 4 0.039
phosphate containing compound metabolic process GO:0006796 108 0.039
cell migration involved in gastrulation GO:0042074 79 0.038
positive regulation of wound healing GO:0090303 1 0.038
myeloid leukocyte mediated immunity GO:0002444 1 0.038
epithelial cell migration GO:0010631 25 0.038
phagosome maturation GO:0090382 1 0.037
skeletal system development GO:0001501 181 0.037
positive regulation of cell motility GO:2000147 11 0.036
modification dependent macromolecule catabolic process GO:0043632 3 0.036
germ cell development GO:0007281 22 0.036
regulation of cell morphogenesis GO:0022604 42 0.036
granulocyte chemotaxis GO:0071621 11 0.035
macrophage chemotaxis GO:0048246 3 0.035
phagolysosome assembly GO:0001845 1 0.035
smooth muscle contraction GO:0006939 2 0.035
positive regulation of gtp catabolic process GO:0033126 1 0.035
response to organic substance GO:0010033 153 0.035
i kappab kinase nf kappab signaling GO:0007249 4 0.034
rna metabolic process GO:0016070 219 0.034
synaptic growth at neuromuscular junction GO:0051124 2 0.034
phosphorus metabolic process GO:0006793 109 0.033
cellular localization GO:0051641 97 0.033
cellular component assembly involved in morphogenesis GO:0010927 107 0.033
positive regulation of cellular component movement GO:0051272 11 0.033
interspecies interaction between organisms GO:0044419 4 0.033
tissue migration GO:0090130 37 0.033
neuron projection guidance GO:0097485 86 0.033
t cell differentiation GO:0030217 6 0.033
protein modification process GO:0036211 100 0.032
system process GO:0003008 185 0.032
cellular amine metabolic process GO:0044106 2 0.032
regulation of gtp catabolic process GO:0033124 2 0.032
nucleobase containing compound biosynthetic process GO:0034654 205 0.032
sequestering of metal ion GO:0051238 3 0.031
convergent extension involved in gastrulation GO:0060027 71 0.031
gtp catabolic process GO:0006184 2 0.031
gtp metabolic process GO:0046039 4 0.031
regulation of programmed cell death GO:0043067 101 0.031
muscle cell differentiation GO:0042692 139 0.031
regulation of purine nucleotide catabolic process GO:0033121 2 0.031
stem cell differentiation GO:0048863 117 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
cellular modified amino acid metabolic process GO:0006575 3 0.030
regulation of neurogenesis GO:0050767 87 0.030
negative regulation of immune response GO:0050777 2 0.030
brain development GO:0007420 293 0.030
cell killing GO:0001906 2 0.030
response to drug GO:0042493 3 0.029
regulation of nucleotide catabolic process GO:0030811 2 0.029
positive regulation of transport GO:0051050 2 0.029
vasculature development GO:0001944 278 0.029
regulation of stem cell proliferation GO:0072091 2 0.029
positive regulation of cytoskeleton organization GO:0051495 3 0.029
chemosensory behavior GO:0007635 1 0.029
aromatic compound biosynthetic process GO:0019438 217 0.029
protein phosphorylation GO:0006468 47 0.028
regulation of gtpase activity GO:0043087 2 0.028
microtubule based process GO:0007017 60 0.028
protein metabolic process GO:0019538 183 0.028
rho protein signal transduction GO:0007266 5 0.028
purine nucleotide metabolic process GO:0006163 27 0.028
cell cycle process GO:0022402 53 0.028
single organism transport GO:0044765 206 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.028
positive regulation of cell communication GO:0010647 56 0.027
retinal ganglion cell axon guidance GO:0031290 35 0.027
cellular biosynthetic process GO:0044249 286 0.027
negative regulation of cell communication GO:0010648 96 0.027
cell growth GO:0016049 57 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.027
positive regulation of molecular function GO:0044093 33 0.027
divalent metal ion transport GO:0070838 20 0.027
regulation of cell projection assembly GO:0060491 4 0.026
protein localization GO:0008104 40 0.026
regulation of wound healing GO:0061041 2 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
mononuclear cell proliferation GO:0032943 1 0.025
nucleic acid metabolic process GO:0090304 244 0.025
regulation of protein localization to plasma membrane GO:1903076 1 0.024
endosomal transport GO:0016197 2 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
digestive tract morphogenesis GO:0048546 231 0.024
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.024
neuron recognition GO:0008038 18 0.024
negative regulation of response to stimulus GO:0048585 104 0.024
tissue remodeling GO:0048771 4 0.024
axon extension GO:0048675 45 0.024
regeneration GO:0031099 91 0.023
macromolecule biosynthetic process GO:0009059 227 0.023
programmed cell death GO:0012501 119 0.023
cell proliferation GO:0008283 80 0.023
positive regulation of map kinase activity GO:0043406 3 0.023
neuromast primordium migration GO:0048883 12 0.023
oocyte anterior posterior axis specification GO:0007314 4 0.023
regulation of protein catabolic process GO:0042176 1 0.023
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.023
stem cell proliferation GO:0072089 4 0.022
cytosolic calcium ion transport GO:0060401 3 0.022
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.022
divalent inorganic cation transport GO:0072511 21 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
positive regulation of dna metabolic process GO:0051054 1 0.022
regulation of response to cytokine stimulus GO:0060759 3 0.022
positive regulation of locomotion GO:0040017 14 0.022
oxidoreduction coenzyme metabolic process GO:0006733 1 0.022
positive regulation of multicellular organismal process GO:0051240 52 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
blood circulation GO:0008015 87 0.022
central nervous system projection neuron axonogenesis GO:0021952 15 0.022
protein localization to membrane GO:0072657 9 0.021
wound healing GO:0042060 90 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.021
positive regulation of signaling GO:0023056 56 0.021
homeostasis of number of cells GO:0048872 62 0.021
multicellular organismal metabolic process GO:0044236 2 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
developmental cell growth GO:0048588 52 0.021
single organism cell adhesion GO:0098602 29 0.021
cellular component disassembly GO:0022411 1 0.021
growth GO:0040007 174 0.021
regulation of cell adhesion GO:0030155 15 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
death GO:0016265 121 0.021
lymphocyte proliferation GO:0046651 1 0.020
cellular protein catabolic process GO:0044257 4 0.020
t cell mediated immunity GO:0002456 1 0.020
regulation of dendrite development GO:0050773 3 0.020
organic substance transport GO:0071702 58 0.020
cell death GO:0008219 121 0.020
response to amino acid GO:0043200 2 0.020
myoblast fusion GO:0007520 10 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
cell chemotaxis GO:0060326 17 0.020
regulation of catalytic activity GO:0050790 55 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
positive regulation of cell differentiation GO:0045597 30 0.020
skeletal muscle organ development GO:0060538 78 0.020
ribonucleotide metabolic process GO:0009259 27 0.020
multicellular organism growth GO:0035264 4 0.019
positive regulation of signal transduction GO:0009967 56 0.019
intracellular signal transduction GO:0035556 85 0.019
response to fungus GO:0009620 25 0.019
regulation of response to external stimulus GO:0032101 31 0.019
lamellipodium organization GO:0097581 1 0.019
leukocyte mediated cytotoxicity GO:0001909 1 0.019
monoamine transport GO:0015844 1 0.019
pole plasm assembly GO:0007315 4 0.019
ion transport GO:0006811 114 0.019
embryonic digestive tract morphogenesis GO:0048557 3 0.019
response to alkaloid GO:0043279 2 0.019
cellular protein modification process GO:0006464 100 0.019
regulation of chemotaxis GO:0050920 18 0.019
calcium ion transport GO:0006816 18 0.018
positive regulation of cell adhesion GO:0045785 1 0.018
tissue homeostasis GO:0001894 25 0.018
regulation of leukocyte mediated immunity GO:0002703 1 0.018
negative regulation of multicellular organismal process GO:0051241 69 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
cellular aldehyde metabolic process GO:0006081 4 0.018
lytic vacuole organization GO:0080171 1 0.018
cell adhesion GO:0007155 40 0.018
regulation of developmental growth GO:0048638 38 0.018
metal ion transport GO:0030001 58 0.018
cell fate commitment GO:0045165 99 0.018
nucleic acid templated transcription GO:0097659 181 0.017
positive regulation of developmental process GO:0051094 50 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
rna biosynthetic process GO:0032774 181 0.017
protein dephosphorylation GO:0006470 3 0.017
b cell differentiation GO:0030183 1 0.017
membrane organization GO:0061024 21 0.017
negative regulation of signaling GO:0023057 96 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
protein secretion GO:0009306 1 0.017
neuron migration GO:0001764 22 0.017
regulation of rho protein signal transduction GO:0035023 2 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
tyrosine phosphorylation of stat protein GO:0007260 1 0.016
regulation of neuron differentiation GO:0045664 56 0.016
neuron death GO:0070997 21 0.016
killing of cells of other organism GO:0031640 1 0.016
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.016
cell cell signaling involved in cell fate commitment GO:0045168 12 0.016
collagen metabolic process GO:0032963 2 0.016
multi organism reproductive process GO:0044703 36 0.016
phosphorylation GO:0016310 69 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
membrane fusion GO:0061025 2 0.016
striated muscle tissue development GO:0014706 110 0.016
lymphocyte homeostasis GO:0002260 1 0.016
regulation of gene expression GO:0010468 265 0.016
regulation of cell death GO:0010941 103 0.016
oxidation reduction process GO:0055114 41 0.016
establishment of protein localization to plasma membrane GO:0090002 1 0.016
transcription dna templated GO:0006351 181 0.016
regulation of molecular function GO:0065009 70 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
blood vessel development GO:0001568 246 0.015
regulation of apoptotic signaling pathway GO:2001233 12 0.015
positive regulation of leukocyte migration GO:0002687 2 0.015
apoptotic process GO:0006915 116 0.015
actin filament organization GO:0007015 15 0.015
regulation of anatomical structure size GO:0090066 33 0.015
regulation of axonogenesis GO:0050770 32 0.015
syncytium formation GO:0006949 12 0.015
negative regulation of leukocyte chemotaxis GO:0002689 3 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
divalent inorganic cation homeostasis GO:0072507 22 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
biosynthetic process GO:0009058 294 0.015
anatomical structure homeostasis GO:0060249 36 0.015
immune system development GO:0002520 191 0.015
epithelium migration GO:0090132 25 0.015
gene expression GO:0010467 252 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
regulation of protein modification process GO:0031399 29 0.015
protein import into nucleus GO:0006606 3 0.014
regulation of jak stat cascade GO:0046425 3 0.014
germ cell migration GO:0008354 8 0.014
vasculogenesis GO:0001570 41 0.014
macromolecule methylation GO:0043414 19 0.014
regulation of protein transport GO:0051223 3 0.014
cellular protein complex assembly GO:0043623 19 0.014
reactive oxygen species biosynthetic process GO:1903409 1 0.014
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.014
single organism membrane organization GO:0044802 20 0.014
cellular protein metabolic process GO:0044267 129 0.014
striated muscle cell differentiation GO:0051146 129 0.014
positive regulation of striated muscle cell differentiation GO:0051155 1 0.014
regulation of filopodium assembly GO:0051489 2 0.014
regulation of reproductive process GO:2000241 4 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
regulation of cytokine mediated signaling pathway GO:0001959 3 0.013
astrocyte differentiation GO:0048708 1 0.013
positive regulation of rna biosynthetic process GO:1902680 57 0.013
protein complex subunit organization GO:0071822 46 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
regulation of organelle organization GO:0033043 29 0.013
regulation of behavior GO:0050795 24 0.013
neutrophil homeostasis GO:0001780 1 0.013
positive regulation of cell migration GO:0030335 11 0.013
negative regulation of neutrophil chemotaxis GO:0090024 3 0.013
regulation of growth GO:0040008 42 0.013
cell adhesion mediated by integrin GO:0033627 1 0.013
intracellular mrna localization GO:0008298 1 0.013
regulation of cellular component biogenesis GO:0044087 12 0.013
leukocyte activation GO:0045321 12 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
skeletal muscle fiber development GO:0048741 35 0.013
regulation of system process GO:0044057 40 0.013
immune response regulating signaling pathway GO:0002764 5 0.012
positive regulation of secretion GO:0051047 1 0.012
actomyosin structure organization GO:0031032 53 0.012
cofactor metabolic process GO:0051186 15 0.012
negative regulation of chemotaxis GO:0050922 4 0.012
regulation of phosphate metabolic process GO:0019220 43 0.012
intracellular transport GO:0046907 32 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
chloride transmembrane transport GO:1902476 4 0.012
ras protein signal transduction GO:0007265 7 0.012
spindle localization GO:0051653 12 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
regulation of neutrophil extravasation GO:2000389 1 0.012
single organism intracellular transport GO:1902582 25 0.012
macromolecule modification GO:0043412 111 0.012
biological adhesion GO:0022610 40 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
positive regulation of apoptotic process GO:0043065 29 0.012
negative regulation of kinase activity GO:0033673 4 0.012
modification of morphology or physiology of other organism GO:0035821 4 0.012
organophosphate metabolic process GO:0019637 37 0.012
axon guidance GO:0007411 86 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.012
regulation of protein metabolic process GO:0051246 56 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012

ptpn6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.040
amyloidosis DOID:9120 0 0.040
acquired metabolic disease DOID:0060158 0 0.040
immune system disease DOID:2914 0 0.027
disease of anatomical entity DOID:7 0 0.027
primary immunodeficiency disease DOID:612 0 0.027