Danio rerio

27 known processes

rabep1

rabaptin, RAB GTPase binding effector protein 1

(Aliases: si:ch211-284f22.1)

rabep1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular protein catabolic process GO:0044257 4 0.059
cellular component morphogenesis GO:0032989 336 0.053
aging GO:0007568 2 0.051
neuron differentiation GO:0030182 353 0.051
protein targeting to nucleus GO:0044744 3 0.047
sensory organ development GO:0007423 393 0.044
protein import into nucleus GO:0006606 3 0.044
cellular response to external stimulus GO:0071496 2 0.044
positive regulation of transport GO:0051050 2 0.042
nuclear transport GO:0051169 4 0.037
ubiquitin dependent protein catabolic process GO:0006511 3 0.036
response to chemical GO:0042221 320 0.036
protein localization to nucleus GO:0034504 3 0.035
establishment of protein localization to organelle GO:0072594 4 0.035
morphogenesis of an epithelium GO:0002009 333 0.034
generation of neurons GO:0048699 385 0.034
eye development GO:0001654 277 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.034
fat soluble vitamin metabolic process GO:0006775 4 0.034
cell projection morphogenesis GO:0048858 244 0.033
response to stress GO:0006950 263 0.033
negative regulation of biological process GO:0048519 304 0.033
response to drug GO:0042493 3 0.033
secondary metabolic process GO:0019748 3 0.033
regulation of protein localization to nucleus GO:1900180 2 0.032
larval development GO:0002164 2 0.032
embryonic organ morphogenesis GO:0048562 274 0.032
pigmentation GO:0043473 85 0.032
immune system process GO:0002376 241 0.031
single organism metabolic process GO:0044710 217 0.031
autophagy GO:0006914 4 0.030
pigment cell differentiation GO:0050931 38 0.030
protein import GO:0017038 3 0.030
cellular biosynthetic process GO:0044249 286 0.030
cellular macromolecule metabolic process GO:0044260 391 0.029
embryonic organ development GO:0048568 381 0.029
maintenance of location GO:0051235 4 0.029
chordate embryonic development GO:0043009 271 0.029
negative regulation of protein phosphorylation GO:0001933 4 0.029
response to external stimulus GO:0009605 264 0.028
response to nutrient GO:0007584 3 0.028
cellular component movement GO:0006928 335 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
nuclear import GO:0051170 3 0.028
organelle organization GO:0006996 227 0.027
guanosine containing compound metabolic process GO:1901068 4 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
heterocycle metabolic process GO:0046483 290 0.026
positive regulation of cell cycle GO:0045787 3 0.026
regulation of cytoplasmic transport GO:1903649 4 0.026
gtp metabolic process GO:0046039 4 0.026
brain development GO:0007420 293 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.026
signal transduction GO:0007165 455 0.026
head development GO:0060322 303 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
positive regulation of cell activation GO:0050867 1 0.025
leukocyte proliferation GO:0070661 1 0.025
phagocytosis GO:0006909 3 0.025
regulation of cell activation GO:0050865 1 0.025
modification dependent protein catabolic process GO:0019941 3 0.025
regulation of protein transport GO:0051223 3 0.024
regulation of cytokine production GO:0001817 3 0.024
skeletal system development GO:0001501 181 0.024
regulation of gene expression GO:0010468 265 0.024
stem cell proliferation GO:0072089 4 0.023
single organism nuclear import GO:1902593 3 0.023
positive regulation of catabolic process GO:0009896 4 0.023
small molecule metabolic process GO:0044281 77 0.023
developmental programmed cell death GO:0010623 4 0.023
multicellular organism growth GO:0035264 4 0.023
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.023
single organism membrane fusion GO:0044801 2 0.023
neuron development GO:0048666 262 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
positive regulation of immune effector process GO:0002699 3 0.022
organic substance biosynthetic process GO:1901576 289 0.022
gene expression GO:0010467 252 0.022
cell projection organization GO:0030030 284 0.022
lipid storage GO:0019915 1 0.022
regulation of synapse organization GO:0050807 3 0.022
negative regulation of cellular process GO:0048523 283 0.022
developmental pigmentation GO:0048066 48 0.022
neuroblast proliferation GO:0007405 2 0.022
regulation of multicellular organism growth GO:0040014 4 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
i kappab kinase nf kappab signaling GO:0007249 4 0.021
response to organic substance GO:0010033 153 0.021
cellular lipid metabolic process GO:0044255 36 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
amine metabolic process GO:0009308 2 0.021
nitrogen compound metabolic process GO:0006807 319 0.020
central nervous system development GO:0007417 387 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
exocytosis GO:0006887 1 0.020
neuron projection development GO:0031175 180 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
regulation of protein targeting GO:1903533 2 0.020
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
cellular amine metabolic process GO:0044106 2 0.020
compound eye development GO:0048749 2 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.020
tube morphogenesis GO:0035239 349 0.020
heart development GO:0007507 313 0.020
cell part morphogenesis GO:0032990 246 0.019
digestive tract morphogenesis GO:0048546 231 0.019
mitochondrion organization GO:0007005 4 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.019
gtp catabolic process GO:0006184 2 0.019
angiogenesis GO:0001525 158 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
mononuclear cell proliferation GO:0032943 1 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.018
cellular response to nutrient levels GO:0031669 2 0.018
vasculature development GO:0001944 278 0.018
response to uv GO:0009411 3 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
retina development in camera type eye GO:0060041 146 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
production of molecular mediator of immune response GO:0002440 2 0.018
fertilization GO:0009566 3 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
regulation of metabolic process GO:0019222 359 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
determination of left right symmetry GO:0007368 179 0.017
locomotion GO:0040011 313 0.017
membrane fusion GO:0061025 2 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
cellular response to molecule of bacterial origin GO:0071219 3 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
organelle fusion GO:0048284 3 0.017
regulation of cell communication GO:0010646 232 0.017
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.017
blood vessel development GO:0001568 246 0.017
regulation of cell shape GO:0008360 1 0.017
single fertilization GO:0007338 3 0.017
regulation of protein catabolic process GO:0042176 1 0.017
regulation of reproductive process GO:2000241 4 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
cell migration GO:0016477 237 0.017
sensory organ morphogenesis GO:0090596 200 0.016
cell motility GO:0048870 244 0.016
embryonic heart tube morphogenesis GO:0003143 108 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
regulation of primary metabolic process GO:0080090 311 0.016
response to corticosteroid GO:0031960 1 0.016
regulation of biological quality GO:0065008 263 0.016
spermatid development GO:0007286 2 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
alcohol biosynthetic process GO:0046165 2 0.016
stem cell maintenance GO:0019827 4 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
cytokinesis GO:0000910 3 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
digestive system development GO:0055123 289 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.016
regulation of binding GO:0051098 3 0.016
regulation of response to stimulus GO:0048583 269 0.016
microtubule organizing center organization GO:0031023 1 0.016
regulation of cell killing GO:0031341 2 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of cell death GO:0010941 103 0.015
protein secretion GO:0009306 1 0.015
regulation of developmental process GO:0050793 247 0.015
regulation of synapse assembly GO:0051963 3 0.015
response to glucocorticoid GO:0051384 1 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
lymphocyte proliferation GO:0046651 1 0.015
regulation of signaling GO:0023051 235 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
melanin metabolic process GO:0006582 2 0.015
stem cell division GO:0017145 1 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
localization of cell GO:0051674 244 0.015
neurotransmitter secretion GO:0007269 2 0.015
cell substrate adhesion GO:0031589 4 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
protein metabolic process GO:0019538 183 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
antimicrobial humoral response GO:0019730 2 0.014
heart morphogenesis GO:0003007 156 0.014
centrosome organization GO:0051297 1 0.014
terpenoid metabolic process GO:0006721 15 0.014
regulation of neuronal synaptic plasticity GO:0048168 1 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
response to carbohydrate GO:0009743 3 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
centrosome cycle GO:0007098 1 0.014
negative regulation of kinase activity GO:0033673 4 0.014
response to vitamin GO:0033273 3 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
protein localization to plasma membrane GO:0072659 1 0.014
chemosensory behavior GO:0007635 1 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
lipid metabolic process GO:0006629 52 0.014
adult behavior GO:0030534 2 0.014
digestive tract development GO:0048565 265 0.014
oxoacid metabolic process GO:0043436 31 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
regulation of response to biotic stimulus GO:0002831 2 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
apoptotic process GO:0006915 116 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
camera type eye development GO:0043010 222 0.014
spermatid differentiation GO:0048515 2 0.014
rna metabolic process GO:0016070 219 0.014
organic acid metabolic process GO:0006082 31 0.014
cellular response to starvation GO:0009267 1 0.014
nucleic acid metabolic process GO:0090304 244 0.014
positive regulation of secretion GO:0051047 1 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
programmed cell death GO:0012501 119 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
mesenchymal cell development GO:0014031 78 0.013
blood vessel morphogenesis GO:0048514 216 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
membrane invagination GO:0010324 1 0.013
cilium morphogenesis GO:0060271 85 0.013
negative regulation of protein import into nucleus GO:0042308 2 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
meiotic nuclear division GO:0007126 4 0.013
myeloid cell differentiation GO:0030099 86 0.013
response to monosaccharide GO:0034284 3 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
regulation of autophagy GO:0010506 3 0.013
adherens junction organization GO:0034332 4 0.013
cellular component disassembly GO:0022411 1 0.013
rna localization GO:0006403 4 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
cognition GO:0050890 1 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
monocyte differentiation GO:0030224 2 0.013
regulation of wound healing GO:0061041 2 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of protein binding GO:0043393 3 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
positive regulation of biological process GO:0048518 253 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
female gonad development GO:0008585 4 0.013
xenobiotic metabolic process GO:0006805 4 0.013
regulation of protein complex assembly GO:0043254 3 0.013
regulation of organ growth GO:0046620 3 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of calcium ion transport GO:0051924 2 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
b cell activation GO:0042113 2 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.012
single organism biosynthetic process GO:0044711 71 0.012
cytoskeleton organization GO:0007010 96 0.012
synaptic vesicle localization GO:0097479 1 0.012
embryonic heart tube development GO:0035050 133 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
ameboidal type cell migration GO:0001667 143 0.012
positive regulation of inflammatory response GO:0050729 1 0.012
response to hexose GO:0009746 3 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
cell matrix adhesion GO:0007160 4 0.012
melanocyte differentiation GO:0030318 26 0.012
response to abiotic stimulus GO:0009628 122 0.012
positive regulation of cytokine production GO:0001819 2 0.012
golgi vesicle transport GO:0048193 3 0.012
protein polyubiquitination GO:0000209 4 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
cellular ketone metabolic process GO:0042180 11 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
sensory system development GO:0048880 76 0.012
response to wounding GO:0009611 116 0.012
eye morphogenesis GO:0048592 144 0.012
biosynthetic process GO:0009058 294 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
nuclear migration GO:0007097 3 0.012
regulation of metal ion transport GO:0010959 4 0.012
synaptic vesicle transport GO:0048489 1 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
peptide transport GO:0015833 1 0.012
positive regulation of cell killing GO:0031343 2 0.012
death GO:0016265 121 0.012
somite development GO:0061053 96 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
transcription dna templated GO:0006351 181 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
response to glucose GO:0009749 3 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
mesenchyme development GO:0060485 127 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
specification of symmetry GO:0009799 204 0.012
oxidation reduction process GO:0055114 41 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
homeostatic process GO:0042592 142 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
multi organism process GO:0051704 134 0.011
female sex differentiation GO:0046660 4 0.011
meiotic cell cycle process GO:1903046 3 0.011
determination of bilateral symmetry GO:0009855 204 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
developmental growth GO:0048589 166 0.011
atp catabolic process GO:0006200 4 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
regulation of gtpase activity GO:0043087 2 0.011
small molecule catabolic process GO:0044282 3 0.011
axon development GO:0061564 166 0.011
post embryonic organ development GO:0048569 4 0.011
striated muscle cell development GO:0055002 108 0.011
negative regulation of cytokine production GO:0001818 1 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
heart looping GO:0001947 94 0.011
immune system development GO:0002520 191 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
wound healing GO:0042060 90 0.011
negative regulation of protein transport GO:0051224 3 0.011
regulation of nervous system development GO:0051960 90 0.011
positive regulation of cell division GO:0051781 2 0.011
lateral line system development GO:0048925 76 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
response to alkaloid GO:0043279 2 0.011
protein complex localization GO:0031503 1 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
regulation of dna replication GO:0006275 3 0.011
cilium organization GO:0044782 71 0.011
muscle structure development GO:0061061 196 0.011
intracellular signal transduction GO:0035556 85 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
interspecies interaction between organisms GO:0044419 4 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
positive regulation of epithelial cell differentiation GO:0030858 2 0.011
positive regulation of cellular process GO:0048522 201 0.011
establishment of localization GO:0051234 244 0.011
startle response GO:0001964 4 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
thermosensory behavior GO:0040040 1 0.011
embryonic skeletal joint development GO:0072498 3 0.011
peptidyl serine modification GO:0018209 2 0.010
cell killing GO:0001906 2 0.010
protein polymerization GO:0051258 4 0.010
lipid catabolic process GO:0016042 4 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
positive regulation of epithelial cell migration GO:0010634 2 0.010
regulation of transcription dna templated GO:0006355 213 0.010
transmission of nerve impulse GO:0019226 19 0.010
peptide metabolic process GO:0006518 1 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
blood circulation GO:0008015 87 0.010
regulation of transporter activity GO:0032409 2 0.010
cell death GO:0008219 121 0.010
leukocyte mediated cytotoxicity GO:0001909 1 0.010
cellular protein metabolic process GO:0044267 129 0.010
cellular carbohydrate metabolic process GO:0044262 4 0.010
regulation of apoptotic process GO:0042981 98 0.010
somitogenesis GO:0001756 87 0.010
cellular component assembly GO:0022607 170 0.010
cell morphogenesis GO:0000902 289 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
cellular hormone metabolic process GO:0034754 19 0.010
neurotransmitter transport GO:0006836 2 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
epithelial cell differentiation GO:0030855 116 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
negative regulation of map kinase activity GO:0043407 2 0.010
hemopoiesis GO:0030097 183 0.010
system process GO:0003008 185 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
cellular response to hypoxia GO:0071456 1 0.010
transport GO:0006810 220 0.010
positive regulation of jnk cascade GO:0046330 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
axonogenesis GO:0007409 152 0.010

rabep1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
musculoskeletal system disease DOID:17 0 0.025
disease of metabolism DOID:0014667 0 0.020
nervous system disease DOID:863 0 0.017
bone disease DOID:0080001 0 0.017
connective tissue disease DOID:65 0 0.017
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
cardiovascular system disease DOID:1287 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
inherited metabolic disorder DOID:655 0 0.011