Danio rerio

0 known processes

racgap1

Rac GTPase-activating protein 1

(Aliases: wu:fb92c08,zgc:77839)

racgap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oocyte maturation GO:0001556 4 0.288
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.225
maintenance of location GO:0051235 4 0.208
Human Fly
modification dependent protein catabolic process GO:0019941 3 0.204
larval development GO:0002164 2 0.186
lateral inhibition GO:0046331 1 0.154
organelle fission GO:0048285 23 0.148
Human Worm Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.146
cell fate commitment GO:0045165 99 0.138
Fly
immune system development GO:0002520 191 0.136
regulation of biological quality GO:0065008 263 0.126
Human Fly
proteasomal protein catabolic process GO:0010498 2 0.106
cellular protein catabolic process GO:0044257 4 0.104
nucleobase containing compound metabolic process GO:0006139 274 0.099
Human Worm
modification dependent macromolecule catabolic process GO:0043632 3 0.097
meiotic cell cycle process GO:1903046 3 0.097
Worm
cellular component movement GO:0006928 335 0.094
generation of neurons GO:0048699 385 0.088
Mouse Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.084
cell motility GO:0048870 244 0.080
positive regulation of cell cycle GO:0045787 3 0.078
Human
nuclear division GO:0000280 23 0.077
Human Worm Fly
single organism localization GO:1902578 225 0.075
Human Fly
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.074
Human Fly
stem cell maintenance GO:0019827 4 0.067
meiotic nuclear division GO:0007126 4 0.065
Worm
regulation of oocyte development GO:0060281 3 0.065
regulation of protein catabolic process GO:0042176 1 0.063
nitrogen compound metabolic process GO:0006807 319 0.063
Human Worm
meiotic chromosome segregation GO:0045132 3 0.061
dna catabolic process GO:0006308 1 0.056
meiosis i GO:0007127 1 0.055
organic substance biosynthetic process GO:1901576 289 0.055
regulation of metabolic process GO:0019222 359 0.054
Human Worm
cell migration GO:0016477 237 0.054
mitotic recombination GO:0006312 2 0.052
telomere organization GO:0032200 1 0.051
single organism metabolic process GO:0044710 217 0.051
Human Worm
tube morphogenesis GO:0035239 349 0.049
neuroblast proliferation GO:0007405 2 0.048
Mouse
single organism reproductive process GO:0044702 40 0.048
Human Worm
hematopoietic or lymphoid organ development GO:0048534 191 0.047
gene expression GO:0010467 252 0.047
chromosome segregation GO:0007059 12 0.046
Human
homeostatic process GO:0042592 142 0.044
locomotion GO:0040011 313 0.043
Worm
regulation of meiotic cell cycle GO:0051445 1 0.042
organic cyclic compound metabolic process GO:1901360 301 0.042
Human Worm
heart development GO:0007507 313 0.040
regulation of primary metabolic process GO:0080090 311 0.040
Human Worm
cellular response to oxygen levels GO:0071453 1 0.040
regulation of reproductive process GO:2000241 4 0.039
cellular biosynthetic process GO:0044249 286 0.038
regulation of cell differentiation GO:0045595 142 0.037
cellular aromatic compound metabolic process GO:0006725 295 0.036
Human Worm
gastrulation GO:0007369 208 0.036
regulation of synapse organization GO:0050807 3 0.036
neuron differentiation GO:0030182 353 0.035
Fly
sister chromatid segregation GO:0000819 6 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.033
Human Worm
female meiotic division GO:0007143 2 0.032
Worm
lipid storage GO:0019915 1 0.032
establishment of localization GO:0051234 244 0.031
Human Worm
digestive tract morphogenesis GO:0048546 231 0.030
stem cell proliferation GO:0072089 4 0.030
Mouse
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.030
heterocycle metabolic process GO:0046483 290 0.029
Human Worm
cell cycle GO:0007049 93 0.028
Human Worm Fly
biosynthetic process GO:0009058 294 0.028
single organism organelle organization GO:1902589 199 0.028
Human Fly
cell projection organization GO:0030030 284 0.028
Fly
growth GO:0040007 174 0.028
sensory organ development GO:0007423 393 0.028
small molecule metabolic process GO:0044281 77 0.027
Human Worm
heterocycle biosynthetic process GO:0018130 215 0.027
regulation of dendrite development GO:0050773 3 0.027
embryo development ending in birth or egg hatching GO:0009792 271 0.027
Worm
regulation of cell shape GO:0008360 1 0.027
digestive tract development GO:0048565 265 0.027
negative regulation of catabolic process GO:0009895 3 0.027
aromatic compound biosynthetic process GO:0019438 217 0.027
regulation of cellular protein catabolic process GO:1903362 1 0.026
negative regulation of gene expression GO:0010629 65 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
regulation of cellular biosynthetic process GO:0031326 245 0.025
multi organism reproductive process GO:0044703 36 0.025
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
Human Worm
anterior posterior pattern specification GO:0009952 152 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
Human Worm
response to wounding GO:0009611 116 0.024
microtubule based process GO:0007017 60 0.024
Human Fly
cell growth GO:0016049 57 0.023
b cell activation GO:0042113 2 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
localization of cell GO:0051674 244 0.023
stem cell division GO:0017145 1 0.022
morphogenesis of an epithelium GO:0002009 333 0.021
multi organism process GO:0051704 134 0.021
Human
regulation of chromosome segregation GO:0051983 1 0.021
Human
nucleic acid metabolic process GO:0090304 244 0.021
positive regulation of catabolic process GO:0009896 4 0.021
Human Worm
nuclear migration GO:0007097 3 0.021
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
gamete generation GO:0007276 33 0.020
Human
cell morphogenesis GO:0000902 289 0.020
Fly
neuron development GO:0048666 262 0.020
Fly
establishment of protein localization to organelle GO:0072594 4 0.020
neuroblast differentiation GO:0014016 1 0.020
developmental growth GO:0048589 166 0.019
telomere maintenance GO:0000723 1 0.019
cytokinesis GO:0000910 3 0.019
Human Worm Fly
negative regulation of cellular process GO:0048523 283 0.019
Fly
multicellular organism growth GO:0035264 4 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
g2 m transition of mitotic cell cycle GO:0000086 4 0.019
regulation of metal ion transport GO:0010959 4 0.018
organic substance catabolic process GO:1901575 28 0.018
Human Worm
myeloid cell development GO:0061515 32 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
Human Worm
cellular component morphogenesis GO:0032989 336 0.018
Fly
phagocytosis GO:0006909 3 0.018
establishment or maintenance of cell polarity GO:0007163 29 0.018
peripheral nervous system development GO:0007422 55 0.018
pancreas development GO:0031016 84 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
Human Worm
central nervous system development GO:0007417 387 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
Human Worm
microtubule based movement GO:0007018 33 0.018
negative regulation of biosynthetic process GO:0009890 55 0.018
sensory organ morphogenesis GO:0090596 200 0.017
retina development in camera type eye GO:0060041 146 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
immune system process GO:0002376 241 0.017
cell cycle g2 m phase transition GO:0044839 4 0.017
response to stress GO:0006950 263 0.017
regulation of response to stimulus GO:0048583 269 0.016
Worm Fly
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
maturation of ssu rrna GO:0030490 1 0.016
neuron projection development GO:0031175 180 0.016
Fly
stem cell differentiation GO:0048863 117 0.016
cellular localization GO:0051641 97 0.016
Human Fly
tissue regeneration GO:0042246 74 0.016
gtp metabolic process GO:0046039 4 0.016
Human Worm
positive regulation of cell division GO:0051781 2 0.015
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.015
positive regulation of oocyte development GO:0060282 1 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
cell part morphogenesis GO:0032990 246 0.015
Fly
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
Human Worm
actin polymerization or depolymerization GO:0008154 2 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.014
cellular catabolic process GO:0044248 27 0.014
Human Worm
spindle assembly involved in mitosis GO:0090307 1 0.014
Human Fly
cell surface receptor signaling pathway GO:0007166 325 0.014
Fly
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
Human Worm Fly
mesenchymal cell development GO:0014031 78 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
Human Worm
guanosine containing compound metabolic process GO:1901068 4 0.014
Human Worm
mitochondrion organization GO:0007005 4 0.014
developmental growth involved in morphogenesis GO:0060560 86 0.014
regulation of binding GO:0051098 3 0.014
regulation of cellular component organization GO:0051128 86 0.013
Human Fly
somatic cell dna recombination GO:0016444 1 0.013
catabolic process GO:0009056 32 0.013
Human Worm
regulation of gene expression GO:0010468 265 0.013
embryonic organ development GO:0048568 381 0.013
sexual reproduction GO:0019953 36 0.013
Human
macromolecule modification GO:0043412 111 0.013
regulation of cell development GO:0060284 100 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
regulation of gtpase activity GO:0043087 2 0.013
Human Worm
regulation of biosynthetic process GO:0009889 250 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
Human Worm
chromosome localization GO:0050000 2 0.013
forebrain development GO:0030900 96 0.013
digestive system development GO:0055123 289 0.013
meiotic cell cycle GO:0051321 5 0.013
Worm
stem cell development GO:0048864 82 0.012
gtp catabolic process GO:0006184 2 0.012
Human Worm
negative regulation of biological process GO:0048519 304 0.012
Fly
thymus development GO:0048538 10 0.012
meiosis ii GO:0007135 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
regulation of mrna processing GO:0050684 3 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
phosphorus metabolic process GO:0006793 109 0.011
Human Worm
negative regulation of collateral sprouting GO:0048671 2 0.011
single organism biosynthetic process GO:0044711 71 0.011
reciprocal dna recombination GO:0035825 1 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
regulation of transcription dna templated GO:0006355 213 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
Human Worm
carboxylic acid metabolic process GO:0019752 22 0.011
mitotic cytokinesis GO:0000281 3 0.011
Human Worm Fly
positive regulation of multi organism process GO:0043902 3 0.011
developmental process involved in reproduction GO:0003006 27 0.011
Worm
hemopoiesis GO:0030097 183 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
convergent extension GO:0060026 118 0.011
aging GO:0007568 2 0.011
single organism catabolic process GO:0044712 13 0.011
Human Worm
regulation of signaling GO:0023051 235 0.011
Worm Fly
fin regeneration GO:0031101 51 0.011
guanosine containing compound catabolic process GO:1901069 2 0.010
Human Worm
cellular amine metabolic process GO:0044106 2 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
Human Worm
single organism nuclear import GO:1902593 3 0.010
trigeminal nerve development GO:0021559 3 0.010
retina morphogenesis in camera type eye GO:0060042 79 0.010
type b pancreatic cell development GO:0003323 4 0.010
protein modification process GO:0036211 100 0.010
aromatic compound catabolic process GO:0019439 15 0.010
Human Worm
negative regulation of mitosis GO:0045839 3 0.010
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.010

racgap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.039
cancer DOID:162 0 0.039
disease of metabolism DOID:0014667 0 0.037
organ system cancer DOID:0050686 0 0.022
inherited metabolic disorder DOID:655 0 0.017