Danio rerio

56 known processes

rdh5

retinol dehydrogenase 5 (11-cis/9-cis)

(Aliases: im:6901729,MGC114091,si:dkey-102c8.5)

rdh5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
phototransduction visible light GO:0007603 2 0.499
phototransduction GO:0007602 2 0.386
cellular response to radiation GO:0071478 4 0.172
detection of visible light GO:0009584 12 0.143
neurological system process GO:0050877 62 0.114
response to organic substance GO:0010033 153 0.101
sensory organ development GO:0007423 393 0.094
catecholamine metabolic process GO:0006584 2 0.094
larval development GO:0002164 2 0.090
regulation of biological quality GO:0065008 263 0.088
Zebrafish
dopamine metabolic process GO:0042417 2 0.088
g protein coupled receptor signaling pathway GO:0007186 74 0.087
detection of stimulus GO:0051606 29 0.081
detection of abiotic stimulus GO:0009582 24 0.081
positive regulation of transport GO:0051050 2 0.078
chemosensory behavior GO:0007635 1 0.076
detection of light stimulus GO:0009583 12 0.076
aging GO:0007568 2 0.075
cellular component morphogenesis GO:0032989 336 0.071
response to chemical GO:0042221 320 0.068
signal transduction GO:0007165 455 0.065
muscle structure development GO:0061061 196 0.064
maintenance of location GO:0051235 4 0.061
regulation of protein transport GO:0051223 3 0.061
cellular aldehyde metabolic process GO:0006081 4 0.058
Zebrafish
organelle assembly GO:0070925 110 0.056
cellular response to chemical stimulus GO:0070887 157 0.055
single organism organelle organization GO:1902589 199 0.055
nucleocytoplasmic transport GO:0006913 4 0.055
single organism metabolic process GO:0044710 217 0.053
cilium morphogenesis GO:0060271 85 0.052
muscle cell development GO:0055001 115 0.052
response to light stimulus GO:0009416 46 0.052
biosynthetic process GO:0009058 294 0.051
cellular biosynthetic process GO:0044249 286 0.051
muscle tissue development GO:0060537 110 0.051
detection of external stimulus GO:0009581 24 0.051
cell matrix adhesion GO:0007160 4 0.050
cellular component biogenesis GO:0044085 178 0.049
locomotion GO:0040011 313 0.049
cell morphogenesis involved in differentiation GO:0000904 195 0.046
rhodopsin mediated signaling pathway GO:0016056 1 0.046
small molecule metabolic process GO:0044281 77 0.046
striated muscle cell differentiation GO:0051146 129 0.044
eye development GO:0001654 277 0.044
single organism biosynthetic process GO:0044711 71 0.044
immune system process GO:0002376 241 0.044
muscle organ development GO:0007517 101 0.043
multicellular organismal signaling GO:0035637 22 0.043
pigmentation GO:0043473 85 0.042
catechol containing compound metabolic process GO:0009712 2 0.042
response to abiotic stimulus GO:0009628 122 0.042
cellular component assembly involved in morphogenesis GO:0010927 107 0.041
nuclear transport GO:0051169 4 0.041
cognition GO:0050890 1 0.041
cilium organization GO:0044782 71 0.041
nitrogen compound metabolic process GO:0006807 319 0.039
protein targeting to nucleus GO:0044744 3 0.039
spermatid differentiation GO:0048515 2 0.039
response to external stimulus GO:0009605 264 0.038
protein import into nucleus GO:0006606 3 0.038
phosphorus metabolic process GO:0006793 109 0.037
organonitrogen compound biosynthetic process GO:1901566 47 0.037
cellular response to organic substance GO:0071310 105 0.037
regulation of reproductive process GO:2000241 4 0.037
sleep GO:0030431 1 0.037
spermatid development GO:0007286 2 0.037
cell projection morphogenesis GO:0048858 244 0.036
establishment of protein localization to organelle GO:0072594 4 0.036
organelle organization GO:0006996 227 0.036
central nervous system development GO:0007417 387 0.036
transmission of nerve impulse GO:0019226 19 0.035
response to vitamin GO:0033273 3 0.035
cytoskeleton organization GO:0007010 96 0.035
protein localization to nucleus GO:0034504 3 0.035
nuclear import GO:0051170 3 0.034
cellular component movement GO:0006928 335 0.034
adult behavior GO:0030534 2 0.033
protein secretion GO:0009306 1 0.033
cellular hormone metabolic process GO:0034754 19 0.033
Zebrafish
cellular component assembly GO:0022607 170 0.031
neuron development GO:0048666 262 0.031
protein metabolic process GO:0019538 183 0.031
chemotaxis GO:0006935 104 0.031
cell projection assembly GO:0030031 64 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
negative regulation of protein phosphorylation GO:0001933 4 0.031
cellular response to endogenous stimulus GO:0071495 68 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
estrogen metabolic process GO:0008210 2 0.030
cell substrate adhesion GO:0031589 4 0.030
positive regulation of cell cycle GO:0045787 3 0.030
synaptic vesicle transport GO:0048489 1 0.030
lipid storage GO:0019915 1 0.029
organonitrogen compound metabolic process GO:1901564 74 0.029
regulation of cytoplasmic transport GO:1903649 4 0.029
regulation of circadian rhythm GO:0042752 4 0.029
protein import GO:0017038 3 0.029
cell projection organization GO:0030030 284 0.028
generation of neurons GO:0048699 385 0.028
cell surface receptor signaling pathway GO:0007166 325 0.028
striated muscle tissue development GO:0014706 110 0.028
response to radiation GO:0009314 51 0.027
action potential GO:0001508 19 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
androgen metabolic process GO:0008209 2 0.027
muscle cell differentiation GO:0042692 139 0.026
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
negative regulation of protein kinase activity GO:0006469 4 0.026
response to nutrient GO:0007584 3 0.026
cell morphogenesis GO:0000902 289 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
regulation of cell shape GO:0008360 1 0.026
axonogenesis GO:0007409 152 0.026
regulation of reactive oxygen species metabolic process GO:2000377 2 0.025
taxis GO:0042330 109 0.025
centrosome organization GO:0051297 1 0.025
immune system development GO:0002520 191 0.025
neuronal action potential GO:0019228 18 0.025
regulation of inflammatory response GO:0050727 2 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
axon development GO:0061564 166 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.024
amine metabolic process GO:0009308 2 0.024
visual perception GO:0007601 17 0.024
response to lipid GO:0033993 60 0.024
diterpenoid metabolic process GO:0016101 15 0.024
rna localization GO:0006403 4 0.024
cellular amine metabolic process GO:0044106 2 0.024
heterocycle metabolic process GO:0046483 290 0.024
response to drug GO:0042493 3 0.024
alcohol biosynthetic process GO:0046165 2 0.024
homeostatic process GO:0042592 142 0.023
regulation of neural precursor cell proliferation GO:2000177 3 0.023
neuroblast proliferation GO:0007405 2 0.023
regulation of protein import into nucleus GO:0042306 2 0.023
response to stress GO:0006950 263 0.023
Zebrafish
regulation of localization GO:0032879 104 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
response to glucocorticoid GO:0051384 1 0.023
single organism nuclear import GO:1902593 3 0.023
heart process GO:0003015 71 0.022
Zebrafish
hormone biosynthetic process GO:0042446 3 0.022
regulation of binding GO:0051098 3 0.022
regulation of cell communication GO:0010646 232 0.022
negative regulation of kinase activity GO:0033673 4 0.022
response to hormone GO:0009725 48 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
microtubule based process GO:0007017 60 0.021
neurotransmitter transport GO:0006836 2 0.021
cellular component disassembly GO:0022411 1 0.021
regulation of protein complex assembly GO:0043254 3 0.021
cilium assembly GO:0042384 58 0.020
alpha amino acid metabolic process GO:1901605 3 0.020
oxidation reduction process GO:0055114 41 0.020
Zebrafish
cell part morphogenesis GO:0032990 246 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
regulation of developmental process GO:0050793 247 0.020
synaptic vesicle localization GO:0097479 1 0.020
cellular localization GO:0051641 97 0.020
protein localization to plasma membrane GO:0072659 1 0.020
establishment of synaptic vesicle localization GO:0097480 1 0.020
circadian sleep wake cycle sleep GO:0050802 1 0.019
regulation of protein targeting GO:1903533 2 0.019
regulation of calcium ion transport GO:0051924 2 0.019
leukocyte proliferation GO:0070661 1 0.019
system process GO:0003008 185 0.019
Zebrafish
single organism transport GO:0044765 206 0.019
circadian sleep wake cycle GO:0042745 2 0.019
transcription dna templated GO:0006351 181 0.019
gene expression GO:0010467 252 0.019
positive regulation of cell activation GO:0050867 1 0.018
multicellular organism growth GO:0035264 4 0.018
neurotransmitter secretion GO:0007269 2 0.018
regulation of dendrite development GO:0050773 3 0.018
response to uv GO:0009411 3 0.018
negative regulation of catabolic process GO:0009895 3 0.018
cellular response to hormone stimulus GO:0032870 39 0.018
regulation of cytokine production GO:0001817 3 0.018
cardiac muscle cell differentiation GO:0055007 30 0.018
neuron differentiation GO:0030182 353 0.018
regulation of synaptic plasticity GO:0048167 1 0.017
vasculature development GO:0001944 278 0.017
regulation of synapse organization GO:0050807 3 0.017
phagocytosis GO:0006909 3 0.017
camera type eye development GO:0043010 222 0.017
stem cell proliferation GO:0072089 4 0.017
cellular response to light stimulus GO:0071482 4 0.017
response to light intensity GO:0009642 1 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of metal ion transport GO:0010959 4 0.016
regulation of synapse assembly GO:0051963 3 0.016
retina development in camera type eye GO:0060041 146 0.016
regulation of autophagy GO:0010506 3 0.016
mononuclear cell proliferation GO:0032943 1 0.016
cellular aromatic compound metabolic process GO:0006725 295 0.016
negative regulation of protein transport GO:0051224 3 0.016
regulation of gene expression GO:0010468 265 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
protein acylation GO:0043543 3 0.016
vitamin a metabolic process GO:0006776 1 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
secondary metabolic process GO:0019748 3 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
lipid homeostasis GO:0055088 3 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.015
gtp catabolic process GO:0006184 2 0.015
dopamine biosynthetic process GO:0042416 2 0.015
circadian sleep wake cycle process GO:0022410 2 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
establishment of protein localization to plasma membrane GO:0090002 1 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
response to steroid hormone GO:0048545 35 0.015
negative regulation of cellular process GO:0048523 283 0.015
hormone metabolic process GO:0042445 19 0.015
Zebrafish
locomotor rhythm GO:0045475 3 0.015
developmental growth GO:0048589 166 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
heart development GO:0007507 313 0.015
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
lipid metabolic process GO:0006629 52 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
retinoic acid receptor signaling pathway GO:0048384 16 0.014
regulation of sodium ion transport GO:0002028 2 0.014
meiotic nuclear division GO:0007126 4 0.014
startle response GO:0001964 4 0.014
macromolecule modification GO:0043412 111 0.014
response to oxygen containing compound GO:1901700 55 0.014
sensory perception of smell GO:0007608 2 0.014
regulation of protein catabolic process GO:0042176 1 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
microtubule organizing center organization GO:0031023 1 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
photoreceptor cell fate commitment GO:0046552 1 0.014
organic cyclic compound metabolic process GO:1901360 301 0.014
retinoid metabolic process GO:0001523 15 0.014
negative regulation of biological process GO:0048519 304 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
cellular protein catabolic process GO:0044257 4 0.014
regulation of biosynthetic process GO:0009889 250 0.014
catechol containing compound biosynthetic process GO:0009713 2 0.014
neuron projection morphogenesis GO:0048812 161 0.014
regulation of cell activation GO:0050865 1 0.014
fat soluble vitamin metabolic process GO:0006775 4 0.014
cellular response to external stimulus GO:0071496 2 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
rna metabolic process GO:0016070 219 0.013
b cell activation GO:0042113 2 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
behavior GO:0007610 74 0.013
regulation of transporter activity GO:0032409 2 0.013
organic substance biosynthetic process GO:1901576 289 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
regulation of response to stimulus GO:0048583 269 0.013
lymphocyte proliferation GO:0046651 1 0.013
response to corticosteroid GO:0031960 1 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
positive regulation of neural precursor cell proliferation GO:2000179 1 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
regulation of apoptotic process GO:0042981 98 0.013
regulation of protein binding GO:0043393 3 0.013
striated muscle cell development GO:0055002 108 0.013
stem cell division GO:0017145 1 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
response to vitamin b3 GO:0033552 2 0.013
gtp metabolic process GO:0046039 4 0.013
response to endogenous stimulus GO:0009719 83 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.012
cellular macromolecule metabolic process GO:0044260 391 0.012
multi organism process GO:0051704 134 0.012
cellular response to starvation GO:0009267 1 0.012
cellular protein metabolic process GO:0044267 129 0.012
carbohydrate homeostasis GO:0033500 1 0.012
posterior lateral line development GO:0048916 38 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
sodium ion transport GO:0006814 24 0.012
response to hypoxia GO:0001666 25 0.012
protein acetylation GO:0006473 2 0.012
positive regulation of cytokine production GO:0001819 2 0.012
regulation of macromolecule metabolic process GO:0060255 317 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
cell proliferation GO:0008283 80 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
positive regulation of biological process GO:0048518 253 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
organic acid catabolic process GO:0016054 3 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
oxoacid metabolic process GO:0043436 31 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.011
protein stabilization GO:0050821 2 0.011
small molecule catabolic process GO:0044282 3 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
protein complex disassembly GO:0043241 1 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
regulation of cell projection assembly GO:0060491 4 0.011
negative regulation of metabolic process GO:0009892 86 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
compound eye development GO:0048749 2 0.011
centrosome cycle GO:0007098 1 0.011
positive regulation of catabolic process GO:0009896 4 0.011
regulation of neurogenesis GO:0050767 87 0.011
regulation of neuronal synaptic plasticity GO:0048168 1 0.011
ion transport GO:0006811 114 0.011
positive regulation of secretion GO:0051047 1 0.011
regulation of metabolic process GO:0019222 359 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
endomembrane system organization GO:0010256 13 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
multi organism cellular process GO:0044764 2 0.011
sensory perception of light stimulus GO:0050953 19 0.011
establishment of localization GO:0051234 244 0.011
growth GO:0040007 174 0.011
brain development GO:0007420 293 0.011
acylglycerol homeostasis GO:0055090 2 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
single organism localization GO:1902578 225 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
interaction with host GO:0051701 4 0.011
digestive tract morphogenesis GO:0048546 231 0.011
Zebrafish
regulation of multicellular organismal development GO:2000026 223 0.011
apical junction assembly GO:0043297 1 0.011
light adaption GO:0036367 1 0.011
autophagy GO:0006914 4 0.011
cellular amino acid biosynthetic process GO:0008652 2 0.011
response to organic cyclic compound GO:0014070 51 0.011
sarcomere organization GO:0045214 26 0.011
macromolecular complex disassembly GO:0032984 1 0.011
response to ketone GO:1901654 1 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
glial cell migration GO:0008347 3 0.010
cardiac conduction GO:0061337 3 0.010
intracellular receptor signaling pathway GO:0030522 30 0.010
response to monosaccharide GO:0034284 3 0.010
response to alkaloid GO:0043279 2 0.010
mitochondrion organization GO:0007005 4 0.010
rna 3 end processing GO:0031123 2 0.010
protein modification process GO:0036211 100 0.010
vesicle localization GO:0051648 27 0.010
actomyosin structure organization GO:0031032 53 0.010
sensory perception of pain GO:0019233 1 0.010
actin cytoskeleton organization GO:0030036 63 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.010
myeloid cell differentiation GO:0030099 86 0.010
cell migration GO:0016477 237 0.010
thermosensory behavior GO:0040040 1 0.010
cell aging GO:0007569 2 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
positive regulation of gtpase activity GO:0043547 1 0.010

rdh5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
musculoskeletal system disease DOID:17 0 0.021
nervous system disease DOID:863 0 0.017
disease of metabolism DOID:0014667 0 0.014
cardiovascular system disease DOID:1287 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.010