Danio rerio

0 known processes

rdh8

retinol dehydrogenase 8

(Aliases: MGC174487,zfprRDH2,zf1.1,cb501,MGC73081,zgc:73081)

rdh8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurological system process GO:0050877 62 0.356
Mouse
axonogenesis GO:0007409 152 0.355
membrane repolarization GO:0086009 2 0.336
cell migration GO:0016477 237 0.316
larval development GO:0002164 2 0.313
locomotion GO:0040011 313 0.310
cell projection morphogenesis GO:0048858 244 0.294
central nervous system development GO:0007417 387 0.288
mesenchyme development GO:0060485 127 0.286
negative regulation of biological process GO:0048519 304 0.252
generation of neurons GO:0048699 385 0.211
response to organic substance GO:0010033 153 0.209
morphogenesis of an epithelium GO:0002009 333 0.198
cation transport GO:0006812 81 0.195
cell motility GO:0048870 244 0.189
cell projection organization GO:0030030 284 0.188
circadian rhythm GO:0007623 19 0.180
cell part morphogenesis GO:0032990 246 0.170
mesenchymal cell development GO:0014031 78 0.167
neuron projection guidance GO:0097485 86 0.165
muscle tissue development GO:0060537 110 0.160
neuron development GO:0048666 262 0.159
negative regulation of cellular process GO:0048523 283 0.156
response to chemical GO:0042221 320 0.139
axon development GO:0061564 166 0.134
cellular response to endogenous stimulus GO:0071495 68 0.132
ion transport GO:0006811 114 0.130
system process GO:0003008 185 0.126
Mouse
cellular component movement GO:0006928 335 0.124
localization of cell GO:0051674 244 0.120
sensory organ development GO:0007423 393 0.109
digestive tract morphogenesis GO:0048546 231 0.108
cell morphogenesis involved in differentiation GO:0000904 195 0.105
muscle structure development GO:0061061 196 0.101
rna biosynthetic process GO:0032774 181 0.098
taxis GO:0042330 109 0.095
cellular amino acid biosynthetic process GO:0008652 2 0.091
cell surface receptor signaling pathway GO:0007166 325 0.091
response to endogenous stimulus GO:0009719 83 0.089
lateral line development GO:0048882 66 0.088
cellular aldehyde metabolic process GO:0006081 4 0.088
ion transmembrane transport GO:0034220 91 0.087
regulation of circadian rhythm GO:0042752 4 0.087
muscle organ development GO:0007517 101 0.086
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.086
regulation of biological quality GO:0065008 263 0.084
Zebrafish Mouse
mesenchymal cell differentiation GO:0048762 87 0.084
transmembrane transport GO:0055085 120 0.083
positive regulation of cellular process GO:0048522 201 0.080
response to light stimulus GO:0009416 46 0.078
striated muscle tissue development GO:0014706 110 0.076
digestive system development GO:0055123 289 0.075
specification of symmetry GO:0009799 204 0.074
axon guidance GO:0007411 86 0.073
regulation of locomotion GO:0040012 55 0.072
single organism metabolic process GO:0044710 217 0.069
Zebrafish Mouse
transport GO:0006810 220 0.068
determination of bilateral symmetry GO:0009855 204 0.068
macromolecule biosynthetic process GO:0009059 227 0.066
positive regulation of transport GO:0051050 2 0.065
stem cell development GO:0048864 82 0.063
endocrine system development GO:0035270 65 0.063
biosynthetic process GO:0009058 294 0.062
Zebrafish
regulation of cellular component organization GO:0051128 86 0.061
response to hormone GO:0009725 48 0.061
cation transmembrane transport GO:0098655 65 0.061
cellular response to organic substance GO:0071310 105 0.061
apoptotic process GO:0006915 116 0.060
regulation of localization GO:0032879 104 0.059
transmission of nerve impulse GO:0019226 19 0.059
rhythmic process GO:0048511 21 0.059
cellular response to hormone stimulus GO:0032870 39 0.058
locomotor rhythm GO:0045475 3 0.058
transcription dna templated GO:0006351 181 0.058
metal ion transport GO:0030001 58 0.055
neuron projection morphogenesis GO:0048812 161 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.054
inorganic ion transmembrane transport GO:0098660 57 0.053
establishment of localization GO:0051234 244 0.053
single organism organelle organization GO:1902589 199 0.052
stem cell maintenance GO:0019827 4 0.052
modification dependent macromolecule catabolic process GO:0043632 3 0.051
digestive tract development GO:0048565 265 0.050
detection of external stimulus GO:0009581 24 0.049
neuron projection development GO:0031175 180 0.049
proteasomal protein catabolic process GO:0010498 2 0.049
circadian sleep wake cycle sleep GO:0050802 1 0.049
protein metabolic process GO:0019538 183 0.048
determination of left right symmetry GO:0007368 179 0.048
regulation of cell morphogenesis GO:0022604 42 0.047
regulation of establishment of protein localization GO:0070201 4 0.047
embryonic appendage morphogenesis GO:0035113 30 0.047
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.046
ubiquitin dependent protein catabolic process GO:0006511 3 0.045
regulation of signal transduction GO:0009966 225 0.045
cellular component morphogenesis GO:0032989 336 0.045
blood vessel development GO:0001568 246 0.044
fin development GO:0033333 77 0.044
regulation of rna biosynthetic process GO:2001141 213 0.044
cellular macromolecule metabolic process GO:0044260 391 0.043
cell morphogenesis GO:0000902 289 0.043
cellular response to chemical stimulus GO:0070887 157 0.043
neuromast development GO:0048884 46 0.043
embryonic limb morphogenesis GO:0030326 2 0.042
neuron differentiation GO:0030182 353 0.042
myofibril assembly GO:0030239 48 0.042
regulation of cell shape GO:0008360 1 0.042
positive regulation of cellular component biogenesis GO:0044089 3 0.042
cell death GO:0008219 121 0.042
regulation of neuron projection development GO:0010975 40 0.042
death GO:0016265 121 0.042
cellular protein catabolic process GO:0044257 4 0.041
neural crest cell differentiation GO:0014033 72 0.041
regulation of developmental process GO:0050793 247 0.041
homeostatic process GO:0042592 142 0.040
regulation of transport GO:0051049 45 0.039
skeletal system development GO:0001501 181 0.039
cilium morphogenesis GO:0060271 85 0.039
multicellular organismal response to stress GO:0033555 2 0.038
regulation of protein transport GO:0051223 3 0.038
chemotaxis GO:0006935 104 0.038
negative regulation of neurogenesis GO:0050768 20 0.037
inorganic cation transmembrane transport GO:0098662 50 0.037
regulation of cellular protein catabolic process GO:1903362 1 0.037
establishment of protein localization to organelle GO:0072594 4 0.037
neuron projection extension GO:1990138 45 0.036
vasculature development GO:0001944 278 0.036
development of primary female sexual characteristics GO:0046545 4 0.036
cellular nitrogen compound metabolic process GO:0034641 290 0.036
positive regulation of biological process GO:0048518 253 0.036
aging GO:0007568 2 0.036
cell proliferation GO:0008283 80 0.035
action potential GO:0001508 19 0.035
negative regulation of kinase activity GO:0033673 4 0.034
regulation of apoptotic process GO:0042981 98 0.034
appendage morphogenesis GO:0035107 56 0.033
regulation of metal ion transport GO:0010959 4 0.033
regulation of cell differentiation GO:0045595 142 0.033
gene expression GO:0010467 252 0.032
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.032
single organism transport GO:0044765 206 0.032
negative regulation of protein kinase activity GO:0006469 4 0.032
regulation of cell communication GO:0010646 232 0.031
regulation of macromolecule metabolic process GO:0060255 317 0.031
programmed cell death GO:0012501 119 0.031
response to abiotic stimulus GO:0009628 122 0.031
nucleocytoplasmic transport GO:0006913 4 0.031
regulation of biosynthetic process GO:0009889 250 0.031
macromolecular complex subunit organization GO:0043933 74 0.031
regulation of protein catabolic process GO:0042176 1 0.031
response to external stimulus GO:0009605 264 0.031
cellular response to growth factor stimulus GO:0071363 39 0.031
ameboidal type cell migration GO:0001667 143 0.031
regulation of cell motility GO:2000145 46 0.030
cell projection assembly GO:0030031 64 0.030
embryonic organ development GO:0048568 381 0.030
positive regulation of cell death GO:0010942 29 0.029
b cell activation GO:0042113 2 0.029
behavior GO:0007610 74 0.029
epithelial cell differentiation GO:0030855 116 0.029
cell substrate adhesion GO:0031589 4 0.029
heart development GO:0007507 313 0.028
nuclear import GO:0051170 3 0.028
nuclear transport GO:0051169 4 0.028
cellular response to radiation GO:0071478 4 0.028
regulation of rna metabolic process GO:0051252 224 0.028
regulation of signaling GO:0023051 235 0.028
regulation of synapse organization GO:0050807 3 0.028
heterocycle metabolic process GO:0046483 290 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
developmental growth involved in morphogenesis GO:0060560 86 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
biological adhesion GO:0022610 40 0.027
startle response GO:0001964 4 0.027
cell adhesion GO:0007155 40 0.027
regulation of cytoplasmic transport GO:1903649 4 0.027
neuronal action potential GO:0019228 18 0.027
regulation of cell migration GO:0030334 40 0.026
positive regulation of apoptotic process GO:0043065 29 0.026
amine metabolic process GO:0009308 2 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
dorsal ventral pattern formation GO:0009953 125 0.026
regulation of neuron differentiation GO:0045664 56 0.026
modification dependent protein catabolic process GO:0019941 3 0.025
protein import GO:0017038 3 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
regulation of dendrite development GO:0050773 3 0.025
striated muscle cell differentiation GO:0051146 129 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
endoderm development GO:0007492 49 0.025
positive regulation of programmed cell death GO:0043068 29 0.025
cellular component assembly GO:0022607 170 0.024
cellular amine metabolic process GO:0044106 2 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
response to nitrogen compound GO:1901698 19 0.024
cellular amino acid metabolic process GO:0006520 7 0.024
negative regulation of multicellular organismal process GO:0051241 69 0.024
cellular macromolecule biosynthetic process GO:0034645 224 0.024
regulation of synapse assembly GO:0051963 3 0.024
negative regulation of cell migration GO:0030336 17 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
hematopoietic or lymphoid organ development GO:0048534 191 0.024
organonitrogen compound metabolic process GO:1901564 74 0.023
positive regulation of cellular metabolic process GO:0031325 94 0.023
cell cell signaling GO:0007267 52 0.023
ear development GO:0043583 127 0.023
nucleic acid metabolic process GO:0090304 244 0.022
regulation of neurogenesis GO:0050767 87 0.022
negative regulation of cell projection organization GO:0031345 9 0.022
camera type eye development GO:0043010 222 0.022
response to growth factor GO:0070848 39 0.022
positive regulation of macromolecule metabolic process GO:0010604 93 0.022
sarcomerogenesis GO:0048769 4 0.022
phosphorylation GO:0016310 69 0.022
maintenance of location GO:0051235 4 0.022
cellular biosynthetic process GO:0044249 286 0.022
Zebrafish
exocrine system development GO:0035272 28 0.021
single organism behavior GO:0044708 24 0.021
regulation of protein metabolic process GO:0051246 56 0.021
regulation of gene expression GO:0010468 265 0.021
female sex differentiation GO:0046660 4 0.021
alpha amino acid metabolic process GO:1901605 3 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
tube morphogenesis GO:0035239 349 0.020
immune system development GO:0002520 191 0.020
negative regulation of cell differentiation GO:0045596 46 0.020
response to oxygen containing compound GO:1901700 55 0.020
notochord development GO:0030903 54 0.020
heart contraction GO:0060047 71 0.020
single organism localization GO:1902578 225 0.020
organic acid metabolic process GO:0006082 31 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
regulation of extent of cell growth GO:0061387 29 0.020
lateral line system development GO:0048925 76 0.020
tissue remodeling GO:0048771 4 0.019
negative regulation of cell motility GO:2000146 17 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
sodium ion transport GO:0006814 24 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
Zebrafish
response to stress GO:0006950 263 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.019
negative regulation of apoptotic process GO:0043066 55 0.019
regulation of protein targeting GO:1903533 2 0.019
cellular component disassembly GO:0022411 1 0.019
long chain fatty acid biosynthetic process GO:0042759 1 0.019
negative regulation of locomotion GO:0040013 18 0.019
rna metabolic process GO:0016070 219 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
regulation of primary metabolic process GO:0080090 311 0.019
macromolecule modification GO:0043412 111 0.019
organonitrogen compound biosynthetic process GO:1901566 47 0.018
response to lipid GO:0033993 60 0.018
brain development GO:0007420 293 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
cell type specific apoptotic process GO:0097285 22 0.018
adult behavior GO:0030534 2 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of membrane potential GO:0042391 23 0.018
mononuclear cell proliferation GO:0032943 1 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
protein stabilization GO:0050821 2 0.018
skeletal muscle organ development GO:0060538 78 0.018
response to radiation GO:0009314 51 0.018
axon extension GO:0048675 45 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
circadian sleep wake cycle GO:0042745 2 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
triglyceride homeostasis GO:0070328 2 0.017
synaptic target recognition GO:0008039 1 0.017
regionalization GO:0003002 274 0.017
cellular hormone metabolic process GO:0034754 19 0.017
Zebrafish Mouse
organism emergence from protective structure GO:0071684 4 0.017
developmental growth GO:0048589 166 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
oxoacid metabolic process GO:0043436 31 0.016
protein localization to plasma membrane GO:0072659 1 0.016
eye development GO:0001654 277 0.016
tyrosine phosphorylation of stat protein GO:0007260 1 0.016
appendage development GO:0048736 80 0.016
protein modification process GO:0036211 100 0.016
immune system process GO:0002376 241 0.016
regulation of cell size GO:0008361 29 0.016
negative regulation of developmental process GO:0051093 65 0.016
small molecule biosynthetic process GO:0044283 16 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
positive regulation of cell cycle GO:0045787 3 0.016
cell cycle process GO:0022402 53 0.016
positive regulation of neural precursor cell proliferation GO:2000179 1 0.016
protein heterooligomerization GO:0051291 1 0.016
nitrogen compound metabolic process GO:0006807 319 0.015
protein targeting to nucleus GO:0044744 3 0.015
mechanosensory lateral line system development GO:0048881 49 0.015
developmental cell growth GO:0048588 52 0.015
small molecule metabolic process GO:0044281 77 0.015
Mouse
negative regulation of cellular component movement GO:0051271 18 0.015
lipid homeostasis GO:0055088 3 0.015
multicellular organismal signaling GO:0035637 22 0.015
hormone transport GO:0009914 2 0.015
regulation of programmed cell death GO:0043067 101 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
alcohol biosynthetic process GO:0046165 2 0.015
neuromast deposition GO:0048885 9 0.015
nucleic acid templated transcription GO:0097659 181 0.015
positive regulation of nervous system development GO:0051962 25 0.014
single organism membrane organization GO:0044802 20 0.014
cell growth GO:0016049 57 0.014
gastrulation GO:0007369 208 0.014
smooth muscle contraction GO:0006939 2 0.014
morphogenesis of an epithelial sheet GO:0002011 49 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
mechanosensory behavior GO:0007638 2 0.014
positive regulation of catabolic process GO:0009896 4 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.014
heart morphogenesis GO:0003007 156 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
cellular protein modification process GO:0006464 100 0.014
signal transduction GO:0007165 455 0.014
organic substance biosynthetic process GO:1901576 289 0.014
Zebrafish
cognition GO:0050890 1 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
germ line stem cell maintenance GO:0030718 2 0.013
negative regulation of neuron projection development GO:0010977 9 0.013
regulation of ion transmembrane transport GO:0034765 18 0.013
protein localization to membrane GO:0072657 9 0.013
muscle cell differentiation GO:0042692 139 0.013
epithelial to mesenchymal transition GO:0001837 21 0.013
regulation of metabolic process GO:0019222 359 0.013
neural crest cell development GO:0014032 62 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
otolith development GO:0048840 32 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
hatching GO:0035188 4 0.013
leukocyte proliferation GO:0070661 1 0.013
neurotransmitter transport GO:0006836 2 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
response to steroid hormone GO:0048545 35 0.013
neurotransmitter secretion GO:0007269 2 0.013
posterior lateral line development GO:0048916 38 0.012
macromolecule localization GO:0033036 54 0.012
single organism biosynthetic process GO:0044711 71 0.012
Zebrafish
negative regulation of metabolic process GO:0009892 86 0.012
regulation of cell projection organization GO:0031344 44 0.012
angiogenesis GO:0001525 158 0.012
heart process GO:0003015 71 0.012
single organism nuclear import GO:1902593 3 0.012
cellular component biogenesis GO:0044085 178 0.012
hormone biosynthetic process GO:0042446 3 0.012
Zebrafish
response to organic cyclic compound GO:0014070 51 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
sequestering of calcium ion GO:0051208 3 0.012
protein complex disassembly GO:0043241 1 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
negative regulation of gene expression GO:0010629 65 0.012
response to vitamin GO:0033273 3 0.012
cell substrate junction assembly GO:0007044 2 0.012
cellular localization GO:0051641 97 0.011
sodium ion transmembrane transport GO:0035725 21 0.011
synaptic vesicle recycling GO:0036465 1 0.011
peripheral nervous system development GO:0007422 55 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
single organismal cell cell adhesion GO:0016337 29 0.011
regulation of cell activation GO:0050865 1 0.011
cartilage development GO:0051216 96 0.011
regulation of hormone secretion GO:0046883 2 0.011
cytoskeleton organization GO:0007010 96 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
hormone secretion GO:0046879 2 0.011
negative regulation of cell growth GO:0030308 7 0.011
motor neuron axon guidance GO:0008045 23 0.011
establishment of localization in cell GO:0051649 77 0.011
circulatory system process GO:0003013 87 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
protein secretion GO:0009306 1 0.011
stem cell division GO:0017145 1 0.011
response to peptide hormone GO:0043434 6 0.011
regulation of cytokine production GO:0001817 3 0.011
positive regulation of leukocyte chemotaxis GO:0002690 1 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.011
cellular protein metabolic process GO:0044267 129 0.011
establishment of blood brain barrier GO:0060856 2 0.011
gland development GO:0048732 143 0.011
growth GO:0040007 174 0.010
protein localization to nucleus GO:0034504 3 0.010
convergent extension GO:0060026 118 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
protein dephosphorylation GO:0006470 3 0.010
positive regulation of multicellular organismal process GO:0051240 52 0.010
establishment of rna localization GO:0051236 3 0.010
protein polymerization GO:0051258 4 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
positive regulation of multi organism process GO:0043902 3 0.010
bone remodeling GO:0046849 2 0.010
regulation of developmental growth GO:0048638 38 0.010
regulation of nucleic acid templated transcription GO:1903506 213 0.010
sleep GO:0030431 1 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
sensory system development GO:0048880 76 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
regulation of endocrine process GO:0044060 2 0.010

rdh8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.022