Danio rerio

15 known processes

rfc4

replication factor C (activator 1) 4

(Aliases: rcf4,zgc:64030)

rfc4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 271 0.570
heterocycle metabolic process GO:0046483 290 0.471
larval development GO:0002164 2 0.385
organic cyclic compound metabolic process GO:1901360 301 0.223
cellular aromatic compound metabolic process GO:0006725 295 0.197
meiotic nuclear division GO:0007126 4 0.190
meiotic cell cycle process GO:1903046 3 0.179
meiosis i GO:0007127 1 0.177
organelle organization GO:0006996 227 0.169
cellular nitrogen compound metabolic process GO:0034641 290 0.156
fertilization GO:0009566 3 0.148
single organism organelle organization GO:1902589 199 0.136
aging GO:0007568 2 0.129
cell cycle process GO:0022402 53 0.123
nitrogen compound metabolic process GO:0006807 319 0.121
nucleic acid metabolic process GO:0090304 244 0.110
pyrimidine nucleotide metabolic process GO:0006220 1 0.110
double strand break repair GO:0006302 3 0.102
cell cycle GO:0007049 93 0.102
double strand break repair via homologous recombination GO:0000724 1 0.101
cellular biosynthetic process GO:0044249 286 0.101
single organism metabolic process GO:0044710 217 0.101
retina development in camera type eye GO:0060041 146 0.097
nucleobase containing compound metabolic process GO:0006139 274 0.094
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.094
locomotion GO:0040011 313 0.093
organic substance biosynthetic process GO:1901576 289 0.089
chromosome organization involved in meiosis GO:0070192 1 0.084
organonitrogen compound metabolic process GO:1901564 74 0.076
cellular response to dna damage stimulus GO:0006974 24 0.075
cellular macromolecule metabolic process GO:0044260 391 0.073
rna metabolic process GO:0016070 219 0.072
chromosome organization GO:0051276 31 0.071
purine nucleoside monophosphate catabolic process GO:0009128 4 0.066
pyrimidine containing compound metabolic process GO:0072527 3 0.066
phosphorus metabolic process GO:0006793 109 0.066
sister chromatid cohesion GO:0007062 2 0.066
dna biosynthetic process GO:0071897 3 0.063
nucleoside monophosphate catabolic process GO:0009125 4 0.063
mitotic dna integrity checkpoint GO:0044774 4 0.060
cellular protein catabolic process GO:0044257 4 0.059
response to stress GO:0006950 263 0.054
maintenance of dna repeat elements GO:0043570 2 0.054
cellular macromolecule biosynthetic process GO:0034645 224 0.054
ribose phosphate metabolic process GO:0019693 27 0.054
sensory organ development GO:0007423 393 0.051
rna transport GO:0050658 2 0.051
multi organism process GO:0051704 134 0.051
transport GO:0006810 220 0.051
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.051
cognition GO:0050890 1 0.050
pyrimidine containing compound biosynthetic process GO:0072528 2 0.048
protein complex subunit organization GO:0071822 46 0.047
nucleocytoplasmic transport GO:0006913 4 0.046
modification dependent protein catabolic process GO:0019941 3 0.045
mrna export from nucleus GO:0006406 1 0.044
multi organism reproductive process GO:0044703 36 0.044
muscle structure development GO:0061061 196 0.043
macromolecule biosynthetic process GO:0009059 227 0.042
positive regulation of histone modification GO:0031058 1 0.042
cellular component biogenesis GO:0044085 178 0.041
cellular component assembly GO:0022607 170 0.041
dna metabolic process GO:0006259 27 0.041
meiotic chromosome segregation GO:0045132 3 0.041
regulation of meiotic cell cycle GO:0051445 1 0.039
atp catabolic process GO:0006200 4 0.039
response to alkaloid GO:0043279 2 0.039
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.038
mitotic g2 dna damage checkpoint GO:0007095 3 0.037
regulation of macromolecule metabolic process GO:0060255 317 0.036
regulation of primary metabolic process GO:0080090 311 0.034
regionalization GO:0003002 274 0.034
proteasomal protein catabolic process GO:0010498 2 0.034
rna localization GO:0006403 4 0.033
chemosensory behavior GO:0007635 1 0.032
establishment of localization GO:0051234 244 0.032
camera type eye development GO:0043010 222 0.031
biosynthetic process GO:0009058 294 0.031
regulation of protein catabolic process GO:0042176 1 0.031
eye development GO:0001654 277 0.031
regulation of metabolic process GO:0019222 359 0.031
negative regulation of cellular process GO:0048523 283 0.031
negative regulation of biological process GO:0048519 304 0.030
single fertilization GO:0007338 3 0.029
protein complex assembly GO:0006461 30 0.029
dna catabolic process GO:0006308 1 0.029
phosphate containing compound metabolic process GO:0006796 108 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
nuclear transport GO:0051169 4 0.027
carbohydrate derivative metabolic process GO:1901135 61 0.027
oocyte maturation GO:0001556 4 0.027
modification dependent macromolecule catabolic process GO:0043632 3 0.026
establishment of rna localization GO:0051236 3 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
cell proliferation GO:0008283 80 0.025
cellular response to biotic stimulus GO:0071216 3 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
regulation of histone methylation GO:0031060 3 0.024
reproduction GO:0000003 40 0.024
male meiosis GO:0007140 2 0.024
behavior GO:0007610 74 0.023
regulation of deoxyribonuclease activity GO:0032070 1 0.023
ribonucleoside monophosphate catabolic process GO:0009158 4 0.023
regulation of cytoplasmic transport GO:1903649 4 0.022
cellular response to stress GO:0033554 62 0.022
striated muscle cell development GO:0055002 108 0.022
synapsis GO:0007129 1 0.022
mitotic dna damage checkpoint GO:0044773 4 0.022
cellular localization GO:0051641 97 0.022
female meiotic division GO:0007143 2 0.022
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
nucleobase containing small molecule metabolic process GO:0055086 32 0.021
regulation of chromosome segregation GO:0051983 1 0.021
response to chemical GO:0042221 320 0.021
nucleoside phosphate metabolic process GO:0006753 28 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
cellular component assembly involved in morphogenesis GO:0010927 107 0.020
lymphocyte proliferation GO:0046651 1 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
regulation of cell cycle GO:0051726 52 0.020
regulation of cell death GO:0010941 103 0.019
macromolecular complex assembly GO:0065003 35 0.019
organophosphate metabolic process GO:0019637 37 0.019
maintenance of location GO:0051235 4 0.019
cellular macromolecular complex assembly GO:0034622 24 0.019
protein acetylation GO:0006473 2 0.019
establishment of localization in cell GO:0051649 77 0.018
organism emergence from protective structure GO:0071684 4 0.018
deoxyribonucleotide biosynthetic process GO:0009263 1 0.018
cell morphogenesis GO:0000902 289 0.018
multicellular organism growth GO:0035264 4 0.017
positive regulation of catabolic process GO:0009896 4 0.017
small molecule metabolic process GO:0044281 77 0.017
nuclear division GO:0000280 23 0.017
endocytosis GO:0006897 16 0.017
mrna transport GO:0051028 2 0.017
mononuclear cell proliferation GO:0032943 1 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
catabolic process GO:0009056 32 0.017
single organism reproductive process GO:0044702 40 0.016
cellular catabolic process GO:0044248 27 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
protein complex biogenesis GO:0070271 30 0.016
immune system process GO:0002376 241 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
cellular protein metabolic process GO:0044267 129 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
response to organic substance GO:0010033 153 0.015
developmental process involved in reproduction GO:0003006 27 0.015
macromolecule modification GO:0043412 111 0.015
neuroblast fate determination GO:0007400 1 0.015
reproductive process GO:0022414 40 0.015
regulation of protein transport GO:0051223 3 0.015
gland development GO:0048732 143 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
actomyosin structure organization GO:0031032 53 0.015
organic acid metabolic process GO:0006082 31 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
cellular component morphogenesis GO:0032989 336 0.014
mitotic cell cycle GO:0000278 64 0.014
somatic cell dna recombination GO:0016444 1 0.014
aromatic compound catabolic process GO:0019439 15 0.013
organelle fission GO:0048285 23 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
single organism transport GO:0044765 206 0.013
positive regulation of biological process GO:0048518 253 0.013
glycosyl compound metabolic process GO:1901657 11 0.013
organic cyclic compound catabolic process GO:1901361 15 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
cytoskeleton organization GO:0007010 96 0.012
dna replication GO:0006260 6 0.012
protein acylation GO:0043543 3 0.012
single organism biosynthetic process GO:0044711 71 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
nuclear migration GO:0007097 3 0.012
regulation of cellular component organization GO:0051128 86 0.012
chromosome segregation GO:0007059 12 0.012
ribonucleoside biosynthetic process GO:0042455 2 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.011
oxoacid metabolic process GO:0043436 31 0.011
protein import into nucleus GO:0006606 3 0.011
protein polymerization GO:0051258 4 0.011
heterocycle catabolic process GO:0046700 15 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
purine containing compound metabolic process GO:0072521 29 0.011
gene expression GO:0010467 252 0.011
peptidyl serine modification GO:0018209 2 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
b cell mediated immunity GO:0019724 3 0.011
mitotic cell cycle process GO:1903047 48 0.011
regulation of transcription dna templated GO:0006355 213 0.011
negative regulation of cell death GO:0060548 60 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
nuclear export GO:0051168 1 0.011
cellular protein complex assembly GO:0043623 19 0.011
nucleoside metabolic process GO:0009116 11 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
b cell activation GO:0042113 2 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
intra s dna damage checkpoint GO:0031573 1 0.010
mitotic nuclear division GO:0007067 18 0.010
cellular nitrogen compound catabolic process GO:0044270 15 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010

rfc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.034
reproductive organ cancer DOID:193 0 0.012
disease of metabolism DOID:0014667 0 0.010