Danio rerio

67 known processes

robo1

roundabout homolog 1

robo1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell differentiation GO:0045595 142 0.940
Human Zebrafish Rat Fly
taxis GO:0042330 109 0.925
central nervous system development GO:0007417 387 0.922
Human Zebrafish Mouse Rat Fly
regulation of axon guidance GO:1902667 8 0.912
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.887
Human Zebrafish Rat Fly
cell growth GO:0016049 57 0.873
Zebrafish
regulation of axonogenesis GO:0050770 32 0.867
Human Zebrafish
neuron recognition GO:0008038 18 0.830
Zebrafish Mouse Rat Fly
regulation of developmental process GO:0050793 247 0.790
Human Zebrafish Rat Fly
cellular macromolecule metabolic process GO:0044260 391 0.769
Human
axon extension GO:0048675 45 0.748
Zebrafish
regulation of multicellular organismal development GO:2000026 223 0.739
Human Zebrafish Rat Fly
regulation of axon extension GO:0030516 24 0.710
Zebrafish
regionalization GO:0003002 274 0.696
Zebrafish Fly
larval development GO:0002164 2 0.695
axon choice point recognition GO:0016198 5 0.663
Zebrafish Mouse Rat Fly
axon midline choice point recognition GO:0016199 4 0.661
Zebrafish Mouse Rat Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.635
neuron differentiation GO:0030182 353 0.622
negative chemotaxis GO:0050919 1 0.613
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.613
generation of neurons GO:0048699 385 0.612
morphogenesis of an epithelium GO:0002009 333 0.610
cellular component morphogenesis GO:0032989 336 0.596
regulation of neurogenesis GO:0050767 87 0.589
Human Zebrafish Rat Fly
nucleic acid metabolic process GO:0090304 244 0.589
axon guidance GO:0007411 86 0.578
organic cyclic compound biosynthetic process GO:1901362 223 0.562
chordate embryonic development GO:0043009 271 0.559
positive regulation of rac protein signal transduction GO:0035022 1 0.557
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.550
cellular macromolecule biosynthetic process GO:0034645 224 0.540
regulation of nucleic acid templated transcription GO:1903506 213 0.534
synaptic target recognition GO:0008039 1 0.506
Fly
regulation of gene expression GO:0010468 265 0.504
cell part morphogenesis GO:0032990 246 0.500
outflow tract morphogenesis GO:0003151 1 0.490
Fly
forebrain development GO:0030900 96 0.486
Human Mouse
digestive tract morphogenesis GO:0048546 231 0.460
locomotion GO:0040011 313 0.454
regulation of macromolecule metabolic process GO:0060255 317 0.445
Human
eye development GO:0001654 277 0.443
neuron projection development GO:0031175 180 0.441
rna biosynthetic process GO:0032774 181 0.441
organic cyclic compound metabolic process GO:1901360 301 0.440
sensory organ development GO:0007423 393 0.439
cardiac cell fate commitment GO:0060911 1 0.431
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.429
cell surface receptor signaling pathway GO:0007166 325 0.425
Human Fly
developmental cell growth GO:0048588 52 0.425
Zebrafish
positive regulation of cellular process GO:0048522 201 0.425
Human Zebrafish Fly
vasculature development GO:0001944 278 0.418
Human Zebrafish
regulation of cell morphogenesis GO:0022604 42 0.415
Human Zebrafish Rat
macromolecule biosynthetic process GO:0009059 227 0.415
negative regulation of axon guidance GO:1902668 1 0.399
Zebrafish
rna metabolic process GO:0016070 219 0.399
skeletal system development GO:0001501 181 0.397
neuron projection extension GO:1990138 45 0.387
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.368
heterocycle biosynthetic process GO:0018130 215 0.363
regulation of cell development GO:0060284 100 0.350
Human Zebrafish Rat Fly
gene expression GO:0010467 252 0.345
Human
embryonic skeletal system development GO:0048706 97 0.345
transcription dna templated GO:0006351 181 0.340
cell recognition GO:0008037 19 0.338
Zebrafish Mouse Rat Fly
regulation of cellular metabolic process GO:0031323 320 0.328
Human
chemotaxis GO:0006935 104 0.328
cell projection organization GO:0030030 284 0.328
regulation of axon extension involved in axon guidance GO:0048841 6 0.324
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.322
nucleobase containing compound biosynthetic process GO:0034654 205 0.320
biosynthetic process GO:0009058 294 0.317
skeletal system morphogenesis GO:0048705 102 0.313
protein metabolic process GO:0019538 183 0.312
Human
cell migration GO:0016477 237 0.311
regulation of macromolecule biosynthetic process GO:0010556 225 0.310
nucleobase containing compound metabolic process GO:0006139 274 0.305
negative regulation of macromolecule metabolic process GO:0010605 76 0.304
regulation of nervous system development GO:0051960 90 0.285
Human Zebrafish Rat Fly
nerve development GO:0021675 45 0.282
nitrogen compound metabolic process GO:0006807 319 0.282
regulation of neuron differentiation GO:0045664 56 0.268
Human Zebrafish Rat Fly
cellular component movement GO:0006928 335 0.268
regulation of cellular response to growth factor stimulus GO:0090287 35 0.257
neuron projection guidance GO:0097485 86 0.255
negative regulation of chemotaxis GO:0050922 4 0.254
Human Zebrafish
positive regulation of cell substrate adhesion GO:0010811 1 0.250
Zebrafish
retinal ganglion cell axon guidance GO:0031290 35 0.249
Zebrafish
regulation of biological quality GO:0065008 263 0.248
Zebrafish Fly
organic substance biosynthetic process GO:1901576 289 0.247
growth GO:0040007 174 0.243
Zebrafish Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.242
positive regulation of biological process GO:0048518 253 0.240
Human Zebrafish Fly
cranial nerve development GO:0021545 42 0.231
entrainment of circadian clock GO:0009649 2 0.229
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.219
head development GO:0060322 303 0.211
Human Mouse Fly
regulation of cell projection organization GO:0031344 44 0.211
Human Zebrafish Rat Fly
cell morphogenesis GO:0000902 289 0.208
cell substrate adhesion GO:0031589 4 0.206
Zebrafish
tube morphogenesis GO:0035239 349 0.201
Mouse
collateral sprouting in absence of injury GO:0048669 4 0.199
localization of cell GO:0051674 244 0.193
neuron projection morphogenesis GO:0048812 161 0.192
embryonic organ morphogenesis GO:0048562 274 0.191
neuron development GO:0048666 262 0.191
cellular biosynthetic process GO:0044249 286 0.189
negative regulation of metabolic process GO:0009892 86 0.187
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.187
Zebrafish
positive regulation of signal transduction GO:0009967 56 0.186
Zebrafish
heterocycle metabolic process GO:0046483 290 0.186
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.184
positive regulation of reproductive process GO:2000243 2 0.180
negative regulation of biological process GO:0048519 304 0.178
Human Zebrafish Mouse
positive regulation of gene expression GO:0010628 71 0.177
regulation of cell death GO:0010941 103 0.177
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.177
signal transduction GO:0007165 455 0.172
Human Zebrafish Rat Worm Fly
nucleic acid templated transcription GO:0097659 181 0.171
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.171
Zebrafish
pectoral fin development GO:0033339 50 0.170
olfactory lobe development GO:0021988 4 0.168
Human Mouse
embryonic organ development GO:0048568 381 0.165
Fly
negative regulation of apoptotic process GO:0043066 55 0.164
programmed cell death GO:0012501 119 0.164
Human
motor neuron axon guidance GO:0008045 23 0.159
Fly
blood vessel morphogenesis GO:0048514 216 0.158
Human Zebrafish
regulation of neuron projection development GO:0010975 40 0.156
Human Zebrafish Rat Fly
lamellipodium assembly GO:0030032 1 0.155
Zebrafish
digestive tract development GO:0048565 265 0.154
anterior posterior axon guidance GO:0033564 5 0.153
Zebrafish
regulation of circadian rhythm GO:0042752 4 0.153
Fly
biological adhesion GO:0022610 40 0.151
Human Zebrafish Fly
cellular response to chemical stimulus GO:0070887 157 0.151
Human
positive regulation of cell matrix adhesion GO:0001954 1 0.149
Zebrafish
regulation of cellular component organization GO:0051128 86 0.146
Human Zebrafish Rat Fly
gastrulation GO:0007369 208 0.143
apoptotic process GO:0006915 116 0.142
Human
brain development GO:0007420 293 0.141
Human Mouse Fly
gland development GO:0048732 143 0.140
Human Mouse Fly
axon development GO:0061564 166 0.139
segmentation GO:0035282 97 0.138
single organism metabolic process GO:0044710 217 0.136
axonogenesis GO:0007409 152 0.135
negative regulation of developmental process GO:0051093 65 0.134
Human Zebrafish
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.131
Human Zebrafish Rat
cell motility GO:0048870 244 0.129
primary neural tube formation GO:0014020 1 0.126
peripheral nervous system development GO:0007422 55 0.126
developmental growth GO:0048589 166 0.124
Zebrafish Mouse
organ formation GO:0048645 17 0.123
regulation of synapse organization GO:0050807 3 0.122
Zebrafish
negative regulation of axon extension GO:0030517 7 0.122
Zebrafish
neural tube development GO:0021915 62 0.122
macromolecule modification GO:0043412 111 0.121
regulation of biosynthetic process GO:0009889 250 0.119
system process GO:0003008 185 0.119
Fly
regulation of rna biosynthetic process GO:2001141 213 0.119
epithelial tube formation GO:0072175 19 0.118
response to external stimulus GO:0009605 264 0.118
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.117
Human
embryonic limb morphogenesis GO:0030326 2 0.116
positive regulation of transcription dna templated GO:0045893 57 0.116
aging GO:0007568 2 0.116
hematopoietic or lymphoid organ development GO:0048534 191 0.115
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.114
death GO:0016265 121 0.113
Human
morphogenesis of embryonic epithelium GO:0016331 30 0.112
positive regulation of biosynthetic process GO:0009891 68 0.111
positive regulation of stress activated mapk cascade GO:0032874 3 0.110
regulation of dendrite development GO:0050773 3 0.109
Rat Fly
cellular aromatic compound metabolic process GO:0006725 295 0.109
developmental growth involved in morphogenesis GO:0060560 86 0.109
Zebrafish Mouse
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.108
regulation of extent of cell growth GO:0061387 29 0.108
Zebrafish
regulation of cell growth GO:0001558 29 0.107
Zebrafish
epithelial tube morphogenesis GO:0060562 148 0.107
Mouse
sympathetic nervous system development GO:0048485 3 0.105
neural tube formation GO:0001841 16 0.104
cellular nitrogen compound metabolic process GO:0034641 290 0.104
protein modification process GO:0036211 100 0.103
axon extension involved in axon guidance GO:0048846 10 0.103
Zebrafish
reproduction GO:0000003 40 0.102
regulation of multicellular organism growth GO:0040014 4 0.101
regulation of locomotion GO:0040012 55 0.098
Human Zebrafish Fly
ectodermal placode morphogenesis GO:0071697 32 0.097
peptidyl serine modification GO:0018209 2 0.095
multicellular organism growth GO:0035264 4 0.095
anterior posterior pattern specification GO:0009952 152 0.094
determination of dorsal ventral asymmetry GO:0048262 34 0.094
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.093
iron ion homeostasis GO:0055072 4 0.093
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.092
kidney development GO:0001822 92 0.090
negative regulation of locomotion GO:0040013 18 0.089
Human Zebrafish
positive regulation of cell adhesion GO:0045785 1 0.088
Zebrafish Fly
regulation of programmed cell death GO:0043067 101 0.088
Human
organism emergence from protective structure GO:0071684 4 0.088
digestive system development GO:0055123 289 0.086
regulation of cellular component movement GO:0051270 55 0.086
Zebrafish Fly
regulation of cell matrix adhesion GO:0001952 1 0.085
Zebrafish
cell death GO:0008219 121 0.084
Human
negative regulation of gene expression GO:0010629 65 0.084
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.084
determination of left right symmetry GO:0007368 179 0.083
regulation of cell fate commitment GO:0010453 22 0.082
blood vessel development GO:0001568 246 0.082
Human Zebrafish
neuron remodeling GO:0016322 1 0.082
regulation of response to stimulus GO:0048583 269 0.081
Human Zebrafish
behavior GO:0007610 74 0.080
Human Zebrafish Fly
negative regulation of axonogenesis GO:0050771 7 0.080
Zebrafish
hepaticobiliary system development GO:0061008 98 0.080
phagocytosis engulfment GO:0006911 1 0.079
cellular protein modification process GO:0006464 100 0.078
connective tissue development GO:0061448 99 0.078
hemopoiesis GO:0030097 183 0.077
central nervous system neuron differentiation GO:0021953 74 0.076
Human Zebrafish Mouse
urogenital system development GO:0001655 97 0.076
synaptic growth at neuromuscular junction GO:0051124 2 0.075
formation of primary germ layer GO:0001704 62 0.075
enzyme linked receptor protein signaling pathway GO:0007167 106 0.075
regulation of chemotaxis GO:0050920 18 0.075
Human Zebrafish
specification of organ identity GO:0010092 2 0.074
regulation of localization GO:0032879 104 0.073
Zebrafish Fly
phagocytosis GO:0006909 3 0.073
multi organism process GO:0051704 134 0.073
cell migration involved in gastrulation GO:0042074 79 0.073
regulation of protein kinase b signaling GO:0051896 8 0.073
pancreas development GO:0031016 84 0.072
liver development GO:0001889 96 0.072
mesoderm development GO:0007498 88 0.072
mesenchymal cell development GO:0014031 78 0.072
exocrine system development GO:0035272 28 0.072
Fly
female gonad development GO:0008585 4 0.071
establishment of localization GO:0051234 244 0.071
negative regulation of cellular process GO:0048523 283 0.070
Human Zebrafish Mouse
negative regulation of programmed cell death GO:0043069 58 0.069
transport GO:0006810 220 0.067
dendrite guidance GO:0070983 0 0.066
Fly
nephron development GO:0072006 31 0.065
embryonic camera type eye development GO:0031076 29 0.064
convergent extension involved in organogenesis GO:0060029 10 0.064
telencephalon development GO:0021537 14 0.064
Human Mouse
dorsal ventral pattern formation GO:0009953 125 0.063
Zebrafish
negative regulation of cell death GO:0060548 60 0.063
embryonic cranial skeleton morphogenesis GO:0048701 90 0.063
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.062
nuclear transport GO:0051169 4 0.062
renal system development GO:0072001 94 0.062
cell projection morphogenesis GO:0048858 244 0.061
negative regulation of cell differentiation GO:0045596 46 0.061
Zebrafish
compound eye development GO:0048749 2 0.060
negative regulation of nucleic acid templated transcription GO:1903507 45 0.060
peptidyl serine phosphorylation GO:0018105 1 0.059
axis specification GO:0009798 43 0.059
female sex differentiation GO:0046660 4 0.059
cell cycle GO:0007049 93 0.058
olfactory bulb development GO:0021772 4 0.057
Human Mouse
positive regulation of cell communication GO:0010647 56 0.057
Zebrafish
camera type eye development GO:0043010 222 0.057
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.056
cellular nitrogen compound biosynthetic process GO:0044271 218 0.056
response to growth factor GO:0070848 39 0.056
glycoprotein metabolic process GO:0009100 23 0.056
cell migration involved in heart formation GO:0060974 10 0.056
positive regulation of signaling GO:0023056 56 0.056
Zebrafish
cellular response to nutrient levels GO:0031669 2 0.055
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.055
embryonic pattern specification GO:0009880 44 0.054
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.054
tube formation GO:0035148 25 0.053
heart development GO:0007507 313 0.053
positive regulation of developmental process GO:0051094 50 0.053
Human
cranial nerve morphogenesis GO:0021602 15 0.053
negative regulation of secretion by cell GO:1903531 2 0.053
regulation of cell motility GO:2000145 46 0.052
Zebrafish Fly
positive regulation of rna metabolic process GO:0051254 59 0.051
negative regulation of multicellular organismal process GO:0051241 69 0.051
Human Zebrafish
regulation of cell shape GO:0008360 1 0.051
dendrite development GO:0016358 9 0.050
Rat Fly
anatomical structure homeostasis GO:0060249 36 0.050
Fly
phosphate containing compound metabolic process GO:0006796 108 0.050
formation of anatomical boundary GO:0048859 14 0.050
Fly
lamellipodium organization GO:0097581 1 0.050
Zebrafish
cell fate specification GO:0001708 68 0.049
Fly
retina development in camera type eye GO:0060041 146 0.049
cellular protein metabolic process GO:0044267 129 0.048
Human
eye morphogenesis GO:0048592 144 0.048
response to stress GO:0006950 263 0.048
wnt signaling pathway GO:0016055 80 0.048
maintenance of location GO:0051235 4 0.047
regulation of cell migration GO:0030334 40 0.047
Zebrafish Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.047
regulation of protein ubiquitination GO:0031396 3 0.047
embryonic skeletal joint development GO:0072498 3 0.047
sensory neuron axon guidance GO:0097374 3 0.047
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.047
tube closure GO:0060606 1 0.047
heart looping GO:0001947 94 0.047
activation of jun kinase activity GO:0007257 2 0.046
respiratory system development GO:0060541 5 0.046
Fly
reproductive process GO:0022414 40 0.046
Fly
protein localization to nucleus GO:0034504 3 0.046
muscle organ development GO:0007517 101 0.046
negative regulation of biosynthetic process GO:0009890 55 0.045
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.045
homeostatic process GO:0042592 142 0.045
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.044
cellular response to endogenous stimulus GO:0071495 68 0.043
regulation of cell size GO:0008361 29 0.043
Zebrafish
regulation of rac protein signal transduction GO:0035020 1 0.043
Zebrafish
regulation of signal transduction GO:0009966 225 0.043
Human Zebrafish
positive regulation of neuron projection development GO:0010976 9 0.043
Human
regulation of anatomical structure morphogenesis GO:0022603 130 0.042
Human Zebrafish Rat
stem cell differentiation GO:0048863 117 0.042
Fly
lymphatic endothelial cell differentiation GO:0060836 1 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.042
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.041
angiogenesis GO:0001525 158 0.041
Human Zebrafish
modification dependent protein catabolic process GO:0019941 3 0.041
forebrain regionalization GO:0021871 4 0.041
negative regulation of cellular metabolic process GO:0031324 77 0.041
response to chemical GO:0042221 320 0.041
regulation of cell fate specification GO:0042659 20 0.041
specification of symmetry GO:0009799 204 0.040
Zebrafish
membrane invagination GO:0010324 1 0.040
protein polyubiquitination GO:0000209 4 0.040
determination of heart left right asymmetry GO:0061371 117 0.040
bmp signaling pathway GO:0030509 52 0.040
myeloid cell differentiation GO:0030099 86 0.040
post embryonic organ morphogenesis GO:0048563 1 0.040
regulation of developmental growth GO:0048638 38 0.039
Zebrafish
neuron death GO:0070997 21 0.039
cellular component assembly GO:0022607 170 0.039
Zebrafish
regulation of cell cell adhesion GO:0022407 13 0.039
Fly
regulation of dendrite morphogenesis GO:0048814 3 0.039
Rat
protein secretion GO:0009306 1 0.039
positive regulation of metabolic process GO:0009893 108 0.038
Human
appendage development GO:0048736 80 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.038
regulation of growth GO:0040008 42 0.038
Zebrafish
somitogenesis GO:0001756 87 0.037
negative regulation of response to stimulus GO:0048585 104 0.037
Human Zebrafish
response to organic cyclic compound GO:0014070 51 0.036
optic placode formation GO:0001743 4 0.036
homeostasis of number of cells GO:0048872 62 0.036
innervation GO:0060384 3 0.036
single organism transport GO:0044765 206 0.036
epithelial to mesenchymal transition GO:0001837 21 0.036
neuron migration GO:0001764 22 0.035
Worm Fly
negative regulation of rna metabolic process GO:0051253 48 0.035
positive regulation of cellular biosynthetic process GO:0031328 68 0.035
immune system process GO:0002376 241 0.034
glutamate receptor signaling pathway GO:0007215 1 0.034
regulation of cellular biosynthetic process GO:0031326 245 0.034
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.034
oxoacid metabolic process GO:0043436 31 0.034
cell adhesion GO:0007155 40 0.034
Human Zebrafish Fly
endocrine system development GO:0035270 65 0.034
cardiocyte differentiation GO:0035051 44 0.034
Fly
ear development GO:0043583 127 0.034
positive regulation of ras protein signal transduction GO:0046579 1 0.034
Zebrafish
positive regulation of mrna metabolic process GO:1903313 2 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.033
cellular response to growth factor stimulus GO:0071363 39 0.033
hindbrain development GO:0030902 91 0.033
extrinsic apoptotic signaling pathway GO:0097191 3 0.033
muscle structure development GO:0061061 196 0.033
regulation of intracellular protein transport GO:0033157 3 0.033
negative regulation of cellular biosynthetic process GO:0031327 55 0.033
fertilization GO:0009566 3 0.033
heart formation GO:0060914 13 0.032
muscle tissue development GO:0060537 110 0.032
protein targeting to nucleus GO:0044744 3 0.032
regulation of response to external stimulus GO:0032101 31 0.032
Human Zebrafish
single organism cell adhesion GO:0098602 29 0.032
Fly
ectodermal placode development GO:0071696 37 0.032
central nervous system neuron development GO:0021954 29 0.032
Human Zebrafish Mouse
inner ear development GO:0048839 126 0.032
cytoskeleton organization GO:0007010 96 0.031
positive regulation of response to stimulus GO:0048584 80 0.031
Zebrafish
microtubule based process GO:0007017 60 0.031
regulation of cellular protein metabolic process GO:0032268 52 0.030
Human
regulation of protein transport GO:0051223 3 0.030
establishment of spindle localization GO:0051293 12 0.030
muscle cell differentiation GO:0042692 139 0.030
small molecule metabolic process GO:0044281 77 0.030
diencephalon development GO:0021536 58 0.030
positive regulation of nervous system development GO:0051962 25 0.030
Human
aorta development GO:0035904 4 0.030
positive regulation of rna biosynthetic process GO:1902680 57 0.030
mesenchyme development GO:0060485 127 0.030
protein import GO:0017038 3 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
canonical wnt signaling pathway GO:0060070 48 0.029
endothelial cell fate commitment GO:0060839 3 0.029
regulation of binding GO:0051098 3 0.029
cellular ketone metabolic process GO:0042180 11 0.028
sensory organ morphogenesis GO:0090596 200 0.028
myeloid cell homeostasis GO:0002262 56 0.028
negative regulation of cell migration GO:0030336 17 0.028
response to endogenous stimulus GO:0009719 83 0.028
regulation of autophagy GO:0010506 3 0.028
mitotic cell cycle process GO:1903047 48 0.028
epithelial cell differentiation GO:0030855 116 0.028
negative regulation of rna biosynthetic process GO:1902679 45 0.028
regulation of cell activation GO:0050865 1 0.028
forebrain neuron differentiation GO:0021879 14 0.028
Human Mouse
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.027
notochord development GO:0030903 54 0.027
transcription from rna polymerase ii promoter GO:0006366 80 0.027
embryonic heart tube development GO:0035050 133 0.027
Fly
ameboidal type cell migration GO:0001667 143 0.027
Human Zebrafish Fly
protein import into nucleus GO:0006606 3 0.027
cognition GO:0050890 1 0.027
positive regulation of neuron differentiation GO:0045666 12 0.027
Human
regulation of bmp signaling pathway GO:0030510 39 0.027
regulation of cell communication GO:0010646 232 0.027
Human Zebrafish
ovulation cycle process GO:0022602 2 0.027
nuclear import GO:0051170 3 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.027
hatching GO:0035188 4 0.027
positive regulation of catabolic process GO:0009896 4 0.027
appendage morphogenesis GO:0035107 56 0.027
determination of ventral identity GO:0048264 21 0.026
Zebrafish
positive regulation of neurogenesis GO:0050769 24 0.026
Human
cartilage development GO:0051216 96 0.026
regulation of signaling GO:0023051 235 0.026
Human Zebrafish
embryonic camera type eye morphogenesis GO:0048596 19 0.026
endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262 4 0.026
amine metabolic process GO:0009308 2 0.026
regulation of neural precursor cell proliferation GO:2000177 3 0.026
regulation of protein targeting GO:1903533 2 0.026
positive regulation of cellular metabolic process GO:0031325 94 0.026
Human
cellular component biogenesis GO:0044085 178 0.026
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.025
positive regulation of multi organism process GO:0043902 3 0.025
protein localization to plasma membrane GO:0072659 1 0.025
otic vesicle morphogenesis GO:0071600 34 0.025
cell migration to the midline involved in heart development GO:0003318 12 0.025
cellular response to external stimulus GO:0071496 2 0.025
otic vesicle development GO:0071599 42 0.025
mesenchymal cell differentiation GO:0048762 87 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
positive regulation of axonogenesis GO:0050772 6 0.025
Human
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.025
single organism localization GO:1902578 225 0.025
otic vesicle formation GO:0030916 27 0.025
morphogenesis of an epithelial sheet GO:0002011 49 0.025
establishment of localization in cell GO:0051649 77 0.025
glial cell proliferation GO:0014009 4 0.025
fin development GO:0033333 77 0.025
lateral line development GO:0048882 66 0.025
sprouting angiogenesis GO:0002040 53 0.024
Human
kidney epithelium development GO:0072073 23 0.024
optic nerve morphogenesis GO:0021631 6 0.024
ovulation cycle GO:0042698 2 0.024
branching morphogenesis of a nerve GO:0048755 4 0.024
post embryonic morphogenesis GO:0009886 4 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
regulation of behavior GO:0050795 24 0.023
Human Zebrafish
positive regulation of cell death GO:0010942 29 0.023
Human
erythrocyte differentiation GO:0030218 54 0.023
protein complex subunit organization GO:0071822 46 0.023
lipid storage GO:0019915 1 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
melanin metabolic process GO:0006582 2 0.022
cardiac ventricle development GO:0003231 9 0.022
otic placode formation GO:0043049 23 0.022
regulation of reproductive process GO:2000241 4 0.022
somite development GO:0061053 96 0.021
ectodermal placode formation GO:0060788 26 0.021
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
nephron tubule morphogenesis GO:0072078 1 0.021
photoreceptor cell differentiation GO:0046530 55 0.021
cell migration involved in heart development GO:0060973 22 0.021
regulation of canonical wnt signaling pathway GO:0060828 34 0.021
regulation of protein phosphorylation GO:0001932 18 0.021
dendrite morphogenesis GO:0048813 5 0.021
Rat Fly
macromolecular complex subunit organization GO:0043933 74 0.021
spinal cord development GO:0021510 46 0.021
Rat
negative regulation of signaling GO:0023057 96 0.021
Human
response to organic substance GO:0010033 153 0.020
Human
axonal defasciculation GO:0007414 2 0.020
organic acid metabolic process GO:0006082 31 0.020
cell matrix adhesion GO:0007160 4 0.020
Zebrafish
striated muscle cell differentiation GO:0051146 129 0.020
vesicle mediated transport GO:0016192 22 0.020
single organism nuclear import GO:1902593 3 0.020
regulation of synapse assembly GO:0051963 3 0.020
Zebrafish
mesodermal cell fate commitment GO:0001710 14 0.020

robo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.178
cancer DOID:162 0 0.178
disease of cellular proliferation DOID:14566 0 0.178
organ system cancer DOID:0050686 0 0.178
disease of anatomical entity DOID:7 0 0.151