Danio rerio

85 known processes

robo4

roundabout homolog 4

(Aliases: sc:d0823,wu:fa16f09)

robo4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vasculature development GO:0001944 278 0.842
generation of neurons GO:0048699 385 0.715
Zebrafish Worm Fly
transcription from rna polymerase iii promoter GO:0006383 1 0.399
lymphatic endothelial cell differentiation GO:0060836 1 0.394
heart development GO:0007507 313 0.345
Zebrafish Fly
larval development GO:0002164 2 0.339
endothelial cell fate commitment GO:0060839 3 0.279
blood vessel morphogenesis GO:0048514 216 0.259
regulation of multicellular organismal process GO:0051239 277 0.251
Zebrafish Fly
regulation of metabolic process GO:0019222 359 0.228
regulation of biological quality GO:0065008 263 0.226
Zebrafish Fly
embryonic organ development GO:0048568 381 0.213
Fly
stem cell maintenance GO:0019827 4 0.208
response to chemical GO:0042221 320 0.202
Zebrafish Worm Fly
homeostasis of number of cells GO:0048872 62 0.188
signal transduction GO:0007165 455 0.184
negative regulation of cellular process GO:0048523 283 0.176
Zebrafish Mouse
response to nutrient GO:0007584 3 0.175
lymphatic endothelial cell fate commitment GO:0060838 1 0.163
cell surface receptor signaling pathway GO:0007166 325 0.161
Fly
aging GO:0007568 2 0.159
regulation of fatty acid metabolic process GO:0019217 1 0.156
blood vessel development GO:0001568 246 0.155
neuron differentiation GO:0030182 353 0.150
Zebrafish Worm Fly
negative regulation of biological process GO:0048519 304 0.144
Zebrafish Mouse
reflex GO:0060004 2 0.136
cellular aromatic compound metabolic process GO:0006725 295 0.134
muscle structure development GO:0061061 196 0.131
nucleobase containing compound metabolic process GO:0006139 274 0.127
regulation of heart contraction GO:0008016 32 0.116
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.113
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.110
angiogenesis GO:0001525 158 0.109
cell fate commitment GO:0045165 99 0.106
Fly
regulation of cellular metabolic process GO:0031323 320 0.105
gland development GO:0048732 143 0.105
Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.104
positive regulation of biological process GO:0048518 253 0.104
regulation of gene expression GO:0010468 265 0.103
response to external stimulus GO:0009605 264 0.099
Zebrafish Worm Fly
stem cell proliferation GO:0072089 4 0.098
response to glucose GO:0009749 3 0.097
regulation of primary metabolic process GO:0080090 311 0.094
lymphangiogenesis GO:0001946 25 0.093
morphogenesis of an epithelium GO:0002009 333 0.093
Zebrafish
sprouting angiogenesis GO:0002040 53 0.092
cell substrate adhesion GO:0031589 4 0.089
negative regulation of macromolecule metabolic process GO:0010605 76 0.088
regulation of developmental process GO:0050793 247 0.088
Zebrafish Fly
cell projection organization GO:0030030 284 0.087
morphogenesis of an epithelial sheet GO:0002011 49 0.087
hormone transport GO:0009914 2 0.085
response to bacterium GO:0009617 58 0.085
defense response GO:0006952 47 0.085
macromolecule biosynthetic process GO:0009059 227 0.084
digestive system development GO:0055123 289 0.081
programmed cell death GO:0012501 119 0.081
gene expression GO:0010467 252 0.080
response to stress GO:0006950 263 0.079
regulation of cell shape GO:0008360 1 0.073
ventricular cardiac muscle tissue development GO:0003229 3 0.073
cellular macromolecule metabolic process GO:0044260 391 0.072
central nervous system development GO:0007417 387 0.072
Zebrafish Fly
response to carbohydrate GO:0009743 3 0.070
response to monosaccharide GO:0034284 3 0.070
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.069
regulation of response to stimulus GO:0048583 269 0.068
system process GO:0003008 185 0.067
Fly
cell morphogenesis GO:0000902 289 0.067
Zebrafish Worm Fly
inner ear development GO:0048839 126 0.067
locomotion GO:0040011 313 0.066
lipid storage GO:0019915 1 0.065
tissue homeostasis GO:0001894 25 0.063
axon development GO:0061564 166 0.063
Zebrafish Worm Fly
cellular biosynthetic process GO:0044249 286 0.062
chemosensory behavior GO:0007635 1 0.061
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.061
heterocycle metabolic process GO:0046483 290 0.060
neuron neuron synaptic transmission GO:0007270 1 0.058
positive regulation of catabolic process GO:0009896 4 0.058
cell cell signaling GO:0007267 52 0.058
Zebrafish
inner ear morphogenesis GO:0042472 63 0.058
phagocytosis GO:0006909 3 0.056
maintenance of location GO:0051235 4 0.056
regulation of nervous system development GO:0051960 90 0.056
Zebrafish Fly
epithelial cell differentiation GO:0030855 116 0.055
immune system process GO:0002376 241 0.055
neuron development GO:0048666 262 0.054
Zebrafish Worm Fly
regulation of immune system process GO:0002682 34 0.053
regulation of biosynthetic process GO:0009889 250 0.053
neuron projection development GO:0031175 180 0.053
Zebrafish Worm Fly
muscle cell differentiation GO:0042692 139 0.052
single organism organelle organization GO:1902589 199 0.051
regulation of blood circulation GO:1903522 32 0.051
stem cell division GO:0017145 1 0.050
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.050
cytoskeleton organization GO:0007010 96 0.049
response to hexose GO:0009746 3 0.049
embryonic limb morphogenesis GO:0030326 2 0.048
lymph vessel development GO:0001945 27 0.048
endodermal cell fate determination GO:0007493 2 0.048
embryo development ending in birth or egg hatching GO:0009792 271 0.047
multicellular organismal homeostasis GO:0048871 29 0.046
single organism behavior GO:0044708 24 0.045
liver development GO:0001889 96 0.045
somite development GO:0061053 96 0.045
positive regulation of gtpase activity GO:0043547 1 0.045
immune effector process GO:0002252 23 0.045
positive regulation of phospholipase c activity GO:0010863 1 0.045
cellular ketone metabolic process GO:0042180 11 0.045
multicellular organismal signaling GO:0035637 22 0.044
negative regulation of metabolic process GO:0009892 86 0.044
aorta development GO:0035904 4 0.044
muscle tissue development GO:0060537 110 0.043
nucleic acid metabolic process GO:0090304 244 0.043
regulation of cellular biosynthetic process GO:0031326 245 0.043
aorta morphogenesis GO:0035909 3 0.043
retinoic acid receptor signaling pathway GO:0048384 16 0.043
cell fate specification GO:0001708 68 0.042
Fly
cell proliferation GO:0008283 80 0.042
eye development GO:0001654 277 0.042
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.042
regulation of rna biosynthetic process GO:2001141 213 0.042
cellular component movement GO:0006928 335 0.042
negative regulation of cellular biosynthetic process GO:0031327 55 0.041
macromolecular complex assembly GO:0065003 35 0.041
neuroblast proliferation GO:0007405 2 0.041
hormone secretion GO:0046879 2 0.040
epidermis development GO:0008544 48 0.040
gastrulation with mouth forming second GO:0001702 44 0.040
cellular localization GO:0051641 97 0.040
biosynthetic process GO:0009058 294 0.040
nitrogen compound metabolic process GO:0006807 319 0.040
interaction with host GO:0051701 4 0.040
striated muscle tissue development GO:0014706 110 0.039
guanosine containing compound metabolic process GO:1901068 4 0.039
negative regulation of protein complex assembly GO:0031333 1 0.039
head development GO:0060322 303 0.039
Fly
single fertilization GO:0007338 3 0.039
regulation of system process GO:0044057 40 0.039
biological adhesion GO:0022610 40 0.038
cell aging GO:0007569 2 0.038
cell part morphogenesis GO:0032990 246 0.038
Zebrafish Worm Fly
regulation of response to cytokine stimulus GO:0060759 3 0.038
interspecies interaction between organisms GO:0044419 4 0.038
pericardium morphogenesis GO:0003344 1 0.038
multi organism process GO:0051704 134 0.037
small molecule metabolic process GO:0044281 77 0.037
regulation of cellular ketone metabolic process GO:0010565 7 0.037
lymph vessel morphogenesis GO:0036303 25 0.037
ventral spinal cord development GO:0021517 35 0.037
brain development GO:0007420 293 0.037
Fly
organic substance biosynthetic process GO:1901576 289 0.037
guanosine containing compound catabolic process GO:1901069 2 0.036
regulation of macromolecule metabolic process GO:0060255 317 0.036
anatomical structure homeostasis GO:0060249 36 0.036
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.036
cell adhesion GO:0007155 40 0.036
cellular component morphogenesis GO:0032989 336 0.036
Zebrafish Worm Fly
negative regulation of cell differentiation GO:0045596 46 0.035
Zebrafish
neurological system process GO:0050877 62 0.035
Fly
gtp catabolic process GO:0006184 2 0.035
rna biosynthetic process GO:0032774 181 0.035
sensory perception of chemical stimulus GO:0007606 3 0.035
epiboly GO:0090504 41 0.034
organic cyclic compound metabolic process GO:1901360 301 0.034
regulation of cellular component organization GO:0051128 86 0.034
Zebrafish Fly
signal transduction in absence of ligand GO:0038034 1 0.034
skeletal muscle organ development GO:0060538 78 0.033
negative regulation of biosynthetic process GO:0009890 55 0.033
cellular macromolecule biosynthetic process GO:0034645 224 0.033
negative regulation of cellular metabolic process GO:0031324 77 0.032
developmental growth GO:0048589 166 0.032
Zebrafish
tissue remodeling GO:0048771 4 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.032
dorsal ventral pattern formation GO:0009953 125 0.031
Zebrafish
pronephros development GO:0048793 69 0.031
retinal rod cell development GO:0046548 4 0.031
sensory perception GO:0007600 39 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.030
hepaticobiliary system development GO:0061008 98 0.030
cellular component assembly GO:0022607 170 0.030
urogenital system development GO:0001655 97 0.030
macromolecular complex subunit organization GO:0043933 74 0.030
heart process GO:0003015 71 0.030
cellular nitrogen compound metabolic process GO:0034641 290 0.030
positive regulation of nucleoside metabolic process GO:0045979 1 0.029
myeloid cell homeostasis GO:0002262 56 0.029
response to lipid GO:0033993 60 0.029
lipid catabolic process GO:0016042 4 0.029
transport GO:0006810 220 0.029
actin cytoskeleton organization GO:0030036 63 0.029
anterior posterior pattern specification GO:0009952 152 0.028
chordate embryonic development GO:0043009 271 0.028
phagocytosis engulfment GO:0006911 1 0.027
determination of bilateral symmetry GO:0009855 204 0.027
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.027
myelination GO:0042552 18 0.027
establishment of localization GO:0051234 244 0.027
ear development GO:0043583 127 0.027
gastrulation GO:0007369 208 0.027
metal ion transport GO:0030001 58 0.026
regulation of apoptotic process GO:0042981 98 0.026
cell motility GO:0048870 244 0.026
heart morphogenesis GO:0003007 156 0.025
Zebrafish Fly
epithelial tube morphogenesis GO:0060562 148 0.025
spinal cord motor neuron differentiation GO:0021522 26 0.025
osteoclast differentiation GO:0030316 1 0.025
nucleus localization GO:0051647 8 0.025
regeneration GO:0031099 91 0.025
heart formation GO:0060914 13 0.025
Zebrafish
neuronal action potential GO:0019228 18 0.025
organelle assembly GO:0070925 110 0.025
positive regulation of apoptotic process GO:0043065 29 0.025
regulation of neuron projection development GO:0010975 40 0.025
Zebrafish Fly
digestive tract development GO:0048565 265 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.024
multicellular organism growth GO:0035264 4 0.024
endoderm development GO:0007492 49 0.024
peptide transport GO:0015833 1 0.024
organelle localization GO:0051640 49 0.024
renal absorption GO:0070293 1 0.024
response to acid chemical GO:0001101 17 0.024
embryonic heart tube development GO:0035050 133 0.024
Fly
cellular response to chemical stimulus GO:0070887 157 0.024
regulation of muscle contraction GO:0006937 3 0.023
epidermal cell differentiation GO:0009913 36 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.023
immune system development GO:0002520 191 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.023
protein metabolic process GO:0019538 183 0.023
organ formation GO:0048645 17 0.023
Zebrafish Fly
muscle cell fate determination GO:0007521 1 0.023
alcohol biosynthetic process GO:0046165 2 0.023
cellular response to external stimulus GO:0071496 2 0.023
regulation of myelination GO:0031641 1 0.023
cellular component biogenesis GO:0044085 178 0.022
taxis GO:0042330 109 0.022
Zebrafish Worm Fly
cortical actin cytoskeleton organization GO:0030866 1 0.022
cellular component assembly involved in morphogenesis GO:0010927 107 0.022
negative regulation of rna metabolic process GO:0051253 48 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
single organism reproductive process GO:0044702 40 0.022
Fly
response to biotic stimulus GO:0009607 97 0.022
oxoacid metabolic process GO:0043436 31 0.022
regulation of transcription dna templated GO:0006355 213 0.022
positive regulation of immune effector process GO:0002699 3 0.022
protein complex assembly GO:0006461 30 0.022
cell migration GO:0016477 237 0.022
response to abiotic stimulus GO:0009628 122 0.022
nuclear migration GO:0007097 3 0.022
camera type eye development GO:0043010 222 0.022
meiotic cell cycle process GO:1903046 3 0.021
germ line stem cell maintenance GO:0030718 2 0.021
circulatory system process GO:0003013 87 0.021
heart contraction GO:0060047 71 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.021
Zebrafish Worm Fly
ear morphogenesis GO:0042471 64 0.021
meiotic nuclear division GO:0007126 4 0.021
ensheathment of neurons GO:0007272 18 0.021
transmission of nerve impulse GO:0019226 19 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.020
organelle organization GO:0006996 227 0.020
response to drug GO:0042493 3 0.020
leukocyte differentiation GO:0002521 25 0.020
negative regulation of transcription dna templated GO:0045892 45 0.020
negative regulation of rna biosynthetic process GO:1902679 45 0.020
cellular response to retinoic acid GO:0071300 1 0.020
toll like receptor signaling pathway GO:0002224 4 0.020
renal system development GO:0072001 94 0.020
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
Zebrafish Fly
regulation of skeletal muscle tissue development GO:0048641 4 0.019
positive regulation of nucleic acid templated transcription GO:1903508 57 0.019
cation homeostasis GO:0055080 33 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
neural crest cell migration GO:0001755 42 0.019
response to hormone GO:0009725 48 0.019
developmental growth involved in morphogenesis GO:0060560 86 0.019
Zebrafish
neural tube development GO:0021915 62 0.019
response to external biotic stimulus GO:0043207 97 0.019
segmentation GO:0035282 97 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
positive regulation of cell activation GO:0050867 1 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.018
apoptotic process GO:0006915 116 0.018
connective tissue development GO:0061448 99 0.018
single organism metabolic process GO:0044710 217 0.018
outflow tract morphogenesis GO:0003151 1 0.018
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
somatic muscle development GO:0007525 4 0.018
modification by symbiont of host morphology or physiology GO:0044003 4 0.018
protein complex subunit organization GO:0071822 46 0.018
response to wounding GO:0009611 116 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
hemopoiesis GO:0030097 183 0.018
single organismal cell cell adhesion GO:0016337 29 0.018
Fly
cell matrix adhesion GO:0007160 4 0.018
peptidyl threonine modification GO:0018210 1 0.018
rna metabolic process GO:0016070 219 0.018
actin filament organization GO:0007015 15 0.018
positive regulation of transport GO:0051050 2 0.017
cellular transition metal ion homeostasis GO:0046916 3 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
response to retinoic acid GO:0032526 6 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.017
neuron projection regeneration GO:0031102 16 0.017
regulation of dna replication GO:0006275 3 0.017
sensory perception of mechanical stimulus GO:0050954 16 0.017
melanocyte differentiation GO:0030318 26 0.017
aromatic compound biosynthetic process GO:0019438 217 0.016
pigment cell differentiation GO:0050931 38 0.016
regulation of protein catabolic process GO:0042176 1 0.016
pancreas development GO:0031016 84 0.016
transcription dna templated GO:0006351 181 0.016
viral process GO:0016032 1 0.016
neural retina development GO:0003407 49 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
cytokinesis GO:0000910 3 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
tube morphogenesis GO:0035239 349 0.016
response to organic substance GO:0010033 153 0.016
regulation of cytokine production GO:0001817 3 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
reproduction GO:0000003 40 0.016
regionalization GO:0003002 274 0.016
Zebrafish Fly
gtp metabolic process GO:0046039 4 0.016
neural precursor cell proliferation GO:0061351 20 0.016
positive regulation of cell cycle GO:0045787 3 0.016
regulation of protein targeting GO:1903533 2 0.015
cellular response to stress GO:0033554 62 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
membrane invagination GO:0010324 1 0.015
peripheral nervous system neuron differentiation GO:0048934 28 0.015
organic acid metabolic process GO:0006082 31 0.015
specification of symmetry GO:0009799 204 0.015
Zebrafish
action potential GO:0001508 19 0.015
regulation of signaling GO:0023051 235 0.015
embryonic hemopoiesis GO:0035162 53 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
leukocyte migration GO:0050900 15 0.015
peptidyl serine modification GO:0018209 2 0.015
reactive oxygen species biosynthetic process GO:1903409 1 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
hair cell differentiation GO:0035315 32 0.015
regulation of cell death GO:0010941 103 0.015
growth GO:0040007 174 0.015
Zebrafish
positive regulation of cytokine production GO:0001819 2 0.015
iron ion homeostasis GO:0055072 4 0.015
semicircular canal development GO:0060872 24 0.014
positive regulation of gliogenesis GO:0014015 2 0.014
positive regulation of secretion GO:0051047 1 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
multi organism cellular process GO:0044764 2 0.014
striated muscle cell differentiation GO:0051146 129 0.014
neural crest cell differentiation GO:0014033 72 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
death GO:0016265 121 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
regulation of oligodendrocyte differentiation GO:0048713 1 0.014
regulation of protein transport GO:0051223 3 0.014
membrane fusion GO:0061025 2 0.014
cell differentiation in spinal cord GO:0021515 40 0.014
cell death GO:0008219 121 0.014
regulation of hormone levels GO:0010817 21 0.013
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.013
response to oxygen containing compound GO:1901700 55 0.013
regulation of cell killing GO:0031341 2 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
cellular response to oxygen containing compound GO:1901701 20 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
microtubule based movement GO:0007018 33 0.013
regulation of metal ion transport GO:0010959 4 0.013
epithelial cell fate commitment GO:0072148 11 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
lipid metabolic process GO:0006629 52 0.013
response to nutrient levels GO:0031667 10 0.013
lateral mesoderm development GO:0048368 23 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
cell projection assembly GO:0030031 64 0.013
sensory perception of pain GO:0019233 1 0.013
somitogenesis GO:0001756 87 0.013
regulation of inflammatory response GO:0050727 2 0.013
female sex differentiation GO:0046660 4 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
ribonucleotide metabolic process GO:0009259 27 0.013
eye morphogenesis GO:0048592 144 0.013
determination of pancreatic left right asymmetry GO:0035469 11 0.013
cellular response to organic substance GO:0071310 105 0.013
single organism transport GO:0044765 206 0.013
inorganic ion transmembrane transport GO:0098660 57 0.013
proteasomal protein catabolic process GO:0010498 2 0.012
ameboidal type cell migration GO:0001667 143 0.012
positive regulation of inflammatory response GO:0050729 1 0.012
atp catabolic process GO:0006200 4 0.012
microtubule based process GO:0007017 60 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
blood vessel endothelial cell differentiation GO:0060837 2 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
startle response GO:0001964 4 0.012
Fly
appendage morphogenesis GO:0035107 56 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
synaptic transmission GO:0007268 35 0.012
Zebrafish
regulation of cell development GO:0060284 100 0.012
Zebrafish Fly
localization of cell GO:0051674 244 0.012
regulation of cell projection organization GO:0031344 44 0.012
Zebrafish Fly
response to mechanical stimulus GO:0009612 24 0.012
homeostatic process GO:0042592 142 0.012
Fly
glial cell migration GO:0008347 3 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of lipid transport GO:0032368 4 0.012
limbic system development GO:0021761 16 0.012
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.012
regulation of cell proliferation GO:0042127 37 0.012
positive regulation of exocytosis GO:0045921 1 0.012
positive regulation of translation GO:0045727 1 0.012
positive regulation of blood circulation GO:1903524 2 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
innate immune response GO:0045087 13 0.012
cortical cytoskeleton organization GO:0030865 1 0.011
positive regulation of wound healing GO:0090303 1 0.011
digestive tract morphogenesis GO:0048546 231 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.011
regulation of wound healing GO:0061041 2 0.011
skeletal muscle tissue development GO:0007519 67 0.011
leukocyte proliferation GO:0070661 1 0.011
convergent extension GO:0060026 118 0.011
Zebrafish
cardiac cell development GO:0055006 21 0.011
single organism localization GO:1902578 225 0.011
negative regulation of cytokine production GO:0001818 1 0.011
cell proliferation in forebrain GO:0021846 3 0.011
axonogenesis GO:0007409 152 0.011
Zebrafish Worm Fly
cation transport GO:0006812 81 0.011
intracellular receptor signaling pathway GO:0030522 30 0.011
mitochondrion organization GO:0007005 4 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
negative regulation of cell death GO:0060548 60 0.011
negative chemotaxis GO:0050919 1 0.011
regulation of cell differentiation GO:0045595 142 0.011
Zebrafish Fly
glial cell proliferation GO:0014009 4 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
microtubule cytoskeleton organization GO:0000226 33 0.011
protein homooligomerization GO:0051260 3 0.011
regulation of skeletal muscle fiber development GO:0048742 2 0.011
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.011
endocrine process GO:0050886 2 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
kidney development GO:0001822 92 0.011
neuromuscular process controlling balance GO:0050885 3 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
regulation of cell activation GO:0050865 1 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
nuclear import GO:0051170 3 0.010
regulation of defense response GO:0031347 14 0.010
calcium ion dependent exocytosis GO:0017156 1 0.010
neuroepithelial cell differentiation GO:0060563 26 0.010
forebrain cell migration GO:0021885 1 0.010
response to corticosteroid GO:0031960 1 0.010
striated muscle cell development GO:0055002 108 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
glucose import GO:0046323 2 0.010
transmembrane transport GO:0055085 120 0.010
tyrosine phosphorylation of stat protein GO:0007260 1 0.010
modification of morphology or physiology of other organism GO:0035821 4 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
regulation of embryonic development GO:0045995 47 0.010
regulation of localization GO:0032879 104 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
negative regulation of nucleic acid templated transcription GO:1903507 45 0.010
negative regulation of apoptotic process GO:0043066 55 0.010

robo4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011