Danio rerio

97 known processes

rock2a

rho-associated, coiled-coil containing protein kinase 2a

(Aliases: rok2,rock2)

rock2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 313 0.172
generation of neurons GO:0048699 385 0.155
Mouse Fly
cytokinesis GO:0000910 3 0.147
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.145
Mouse Fly
cellular component biogenesis GO:0044085 178 0.141
Fly
organelle organization GO:0006996 227 0.131
cellular component assembly GO:0022607 170 0.130
Fly
guanosine containing compound catabolic process GO:1901069 2 0.120
cell projection organization GO:0030030 284 0.115
Mouse Fly
regulation of multicellular organismal process GO:0051239 277 0.112
regulation of multicellular organismal development GO:2000026 223 0.111
positive regulation of cellular catabolic process GO:0031331 3 0.109
cellular macromolecule metabolic process GO:0044260 391 0.109
axon development GO:0061564 166 0.107
Fly
single organism organelle organization GO:1902589 199 0.104
organelle assembly GO:0070925 110 0.103
stem cell proliferation GO:0072089 4 0.101
digestive tract development GO:0048565 265 0.097
single organism transport GO:0044765 206 0.097
Fly
larval development GO:0002164 2 0.095
Worm
response to stress GO:0006950 263 0.094
Fly
positive regulation of catabolic process GO:0009896 4 0.091
nucleoside monophosphate catabolic process GO:0009125 4 0.088
neuron differentiation GO:0030182 353 0.085
Mouse Fly
guanosine containing compound metabolic process GO:1901068 4 0.084
cellular ketone metabolic process GO:0042180 11 0.083
localization of cell GO:0051674 244 0.081
maintenance of location GO:0051235 4 0.080
Fly
neuron development GO:0048666 262 0.076
Mouse Fly
nuclear migration GO:0007097 3 0.076
Fly
digestive system development GO:0055123 289 0.075
transport GO:0006810 220 0.075
Fly
regulation of gtp catabolic process GO:0033124 2 0.074
gtp metabolic process GO:0046039 4 0.074
cell substrate adhesion GO:0031589 4 0.072
nitrogen compound metabolic process GO:0006807 319 0.072
embryo development ending in birth or egg hatching GO:0009792 271 0.071
Mouse Worm Fly
organonitrogen compound metabolic process GO:1901564 74 0.071
regulation of synapse organization GO:0050807 3 0.070
cellular amine metabolic process GO:0044106 2 0.070
neuroblast proliferation GO:0007405 2 0.068
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.067
Mouse Fly
cell migration GO:0016477 237 0.066
cellular nitrogen compound metabolic process GO:0034641 290 0.065
erk1 and erk2 cascade GO:0070371 4 0.064
cell morphogenesis GO:0000902 289 0.062
Mouse Worm Fly
muscle structure development GO:0061061 196 0.060
regulation of signaling GO:0023051 235 0.059
Fly
atp catabolic process GO:0006200 4 0.059
skeletal system development GO:0001501 181 0.059
head development GO:0060322 303 0.058
amine metabolic process GO:0009308 2 0.057
lipid storage GO:0019915 1 0.057
system process GO:0003008 185 0.057
cell projection morphogenesis GO:0048858 244 0.057
Mouse Fly
cellular component movement GO:0006928 335 0.056
regulation of cellular ketone metabolic process GO:0010565 7 0.056
regulation of erk1 and erk2 cascade GO:0070372 4 0.053
cellular component morphogenesis GO:0032989 336 0.053
Mouse Worm Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.053
Fly
protein metabolic process GO:0019538 183 0.053
regulation of purine nucleotide catabolic process GO:0033121 2 0.052
regulation of nucleoside metabolic process GO:0009118 2 0.051
embryonic organ morphogenesis GO:0048562 274 0.051
regulation of nucleotide catabolic process GO:0030811 2 0.051
single organism metabolic process GO:0044710 217 0.051
gtp catabolic process GO:0006184 2 0.050
eye development GO:0001654 277 0.050
Fly
regulation of biological quality GO:0065008 263 0.050
Worm Fly
blood vessel development GO:0001568 246 0.049
Human
regulation of cell shape GO:0008360 1 0.049
Worm Fly
regulation of stem cell proliferation GO:0072091 2 0.049
phosphate containing compound metabolic process GO:0006796 108 0.049
Human Fly
single organism localization GO:1902578 225 0.048
Fly
stem cell maintenance GO:0019827 4 0.047
immune system process GO:0002376 241 0.047
positive regulation of gtp catabolic process GO:0033126 1 0.047
regulation of anatomical structure morphogenesis GO:0022603 130 0.046
regulation of dna replication GO:0006275 3 0.046
cellular aromatic compound metabolic process GO:0006725 295 0.046
cytoskeleton dependent cytokinesis GO:0061640 3 0.046
Fly
phagocytosis GO:0006909 3 0.046
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.045
positive regulation of cell matrix adhesion GO:0001954 1 0.045
small molecule metabolic process GO:0044281 77 0.045
oocyte anterior posterior axis specification GO:0007314 4 0.044
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.044
cellular component assembly involved in morphogenesis GO:0010927 107 0.044
regulation of cellular component organization GO:0051128 86 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.043
regulation of macromolecule metabolic process GO:0060255 317 0.043
Fly
regulation of cell communication GO:0010646 232 0.043
Fly
positive regulation of cell cycle GO:0045787 3 0.043
Mouse
regionalization GO:0003002 274 0.042
negative regulation of kinase activity GO:0033673 4 0.042
positive regulation of stress activated mapk cascade GO:0032874 3 0.042
regulation of cellular amino acid metabolic process GO:0006521 0 0.042
muscle cell differentiation GO:0042692 139 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
negative regulation of protein phosphorylation GO:0001933 4 0.041
compound eye development GO:0048749 2 0.040
Fly
cellular carbohydrate metabolic process GO:0044262 4 0.040
regulation of signal transduction GO:0009966 225 0.040
Fly
organic cyclic compound metabolic process GO:1901360 301 0.040
regulation of cellular amine metabolic process GO:0033238 0 0.040
establishment of synaptic vesicle localization GO:0097480 1 0.040
actin filament based movement GO:0030048 1 0.040
Fly
anterior posterior pattern specification GO:0009952 152 0.040
adherens junction organization GO:0034332 4 0.040
regulation of protein catabolic process GO:0042176 1 0.040
multicellular organism growth GO:0035264 4 0.039
regulation of protein complex assembly GO:0043254 3 0.039
sensory organ development GO:0007423 393 0.038
Fly
germ line stem cell maintenance GO:0030718 2 0.038
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.038
regulation of embryonic development GO:0045995 47 0.038
maternal determination of anterior posterior axis embryo GO:0008358 4 0.037
cellular response to nutrient levels GO:0031669 2 0.037
neurotransmitter transport GO:0006836 2 0.037
phosphorus metabolic process GO:0006793 109 0.037
Human Fly
regulation of gtpase activity GO:0043087 2 0.037
chordate embryonic development GO:0043009 271 0.037
Mouse
neuron projection morphogenesis GO:0048812 161 0.036
Mouse Fly
cellular response to external stimulus GO:0071496 2 0.036
biosynthetic process GO:0009058 294 0.036
blood vessel morphogenesis GO:0048514 216 0.036
Human
cellular response to extracellular stimulus GO:0031668 2 0.036
adult behavior GO:0030534 2 0.036
gene expression GO:0010467 252 0.035
central nervous system development GO:0007417 387 0.035
cell adhesion GO:0007155 40 0.035
hematopoietic or lymphoid organ development GO:0048534 191 0.034
single organism cell adhesion GO:0098602 29 0.034
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.034
organic acid metabolic process GO:0006082 31 0.034
regulation of protein polymerization GO:0032271 2 0.034
regulation of cell development GO:0060284 100 0.034
Fly
negative regulation of protein kinase activity GO:0006469 4 0.033
regulation of developmental process GO:0050793 247 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
Fly
cell migration involved in gastrulation GO:0042074 79 0.033
regulation of nitrogen compound metabolic process GO:0051171 251 0.033
taxis GO:0042330 109 0.033
positive regulation of signaling GO:0023056 56 0.033
biological adhesion GO:0022610 40 0.033
Fly
positive regulation of nucleoside metabolic process GO:0045979 1 0.033
vasculature development GO:0001944 278 0.032
Human
cell cycle GO:0007049 93 0.032
Human Mouse Fly
actin polymerization or depolymerization GO:0008154 2 0.032
establishment of localization GO:0051234 244 0.032
Fly
aging GO:0007568 2 0.032
Worm
axonogenesis GO:0007409 152 0.032
Fly
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.030
cell part morphogenesis GO:0032990 246 0.030
Mouse Fly
brain development GO:0007420 293 0.030
regulation of intracellular protein transport GO:0033157 3 0.030
muscle cell development GO:0055001 115 0.030
regulation of neural precursor cell proliferation GO:2000177 3 0.030
cell matrix adhesion GO:0007160 4 0.030
hemopoiesis GO:0030097 183 0.030
ceramide metabolic process GO:0006672 5 0.030
synaptic growth at neuromuscular junction GO:0051124 2 0.030
secondary metabolic process GO:0019748 3 0.030
oxoacid metabolic process GO:0043436 31 0.030
peptidyl serine phosphorylation GO:0018105 1 0.029
nephron tubule morphogenesis GO:0072078 1 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
cell motility GO:0048870 244 0.029
actin cytoskeleton organization GO:0030036 63 0.029
long chain fatty acid metabolic process GO:0001676 1 0.029
embryonic skeletal system morphogenesis GO:0048704 93 0.029
positive regulation of protein complex assembly GO:0031334 2 0.029
autophagy GO:0006914 4 0.028
stem cell development GO:0048864 82 0.028
heterocycle metabolic process GO:0046483 290 0.028
protein localization to plasma membrane GO:0072659 1 0.028
regulation of response to stimulus GO:0048583 269 0.028
Fly
cellular amino acid metabolic process GO:0006520 7 0.028
positive regulation of cell communication GO:0010647 56 0.028
ras protein signal transduction GO:0007265 7 0.028
Rat Fly
positive regulation of transport GO:0051050 2 0.028
somatic muscle development GO:0007525 4 0.028
establishment of protein localization to organelle GO:0072594 4 0.027
lamellipodium organization GO:0097581 1 0.027
positive regulation of biological process GO:0048518 253 0.027
Mouse Fly
mitotic cytokinesis GO:0000281 3 0.027
Fly
modification dependent protein catabolic process GO:0019941 3 0.027
mitotic cell cycle GO:0000278 64 0.027
Fly
regulation of cell activation GO:0050865 1 0.027
regulation of multicellular organism growth GO:0040014 4 0.026
macromolecule modification GO:0043412 111 0.026
Human Fly
neural precursor cell proliferation GO:0061351 20 0.026
response to chemical GO:0042221 320 0.026
segmentation GO:0035282 97 0.026
cell cycle g1 s phase transition GO:0044843 1 0.026
cytoskeleton organization GO:0007010 96 0.026
convergent extension GO:0060026 118 0.026
macromolecular complex assembly GO:0065003 35 0.026
small gtpase mediated signal transduction GO:0007264 8 0.026
Rat Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.026
protein polymerization GO:0051258 4 0.026
regulation of cellular metabolic process GO:0031323 320 0.026
Fly
cilium morphogenesis GO:0060271 85 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.025
protein glycosylation GO:0006486 9 0.025
cilium assembly GO:0042384 58 0.025
positive regulation of nucleotide catabolic process GO:0030813 1 0.025
regulation of synapse assembly GO:0051963 3 0.025
aromatic compound biosynthetic process GO:0019438 217 0.024
neuromuscular process controlling balance GO:0050885 3 0.024
protein import GO:0017038 3 0.024
carbohydrate biosynthetic process GO:0016051 1 0.024
positive regulation of map kinase activity GO:0043406 3 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.024
developmental growth GO:0048589 166 0.024
Fly
single organismal cell cell adhesion GO:0016337 29 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
cellular response to starvation GO:0009267 1 0.024
positive regulation of jnk cascade GO:0046330 3 0.024
exocytosis GO:0006887 1 0.024
stem cell division GO:0017145 1 0.024
cellular response to stress GO:0033554 62 0.023
fertilization GO:0009566 3 0.023
negative regulation of mapk cascade GO:0043409 4 0.023
gastrulation GO:0007369 208 0.023
regulation of metabolic process GO:0019222 359 0.023
Fly
death GO:0016265 121 0.023
Mouse Worm
actin filament polymerization GO:0030041 2 0.023
carbohydrate derivative metabolic process GO:1901135 61 0.023
regulation of localization GO:0032879 104 0.023
Fly
tube morphogenesis GO:0035239 349 0.023
positive regulation of response to stimulus GO:0048584 80 0.023
Fly
carboxylic acid metabolic process GO:0019752 22 0.023
neuron projection development GO:0031175 180 0.023
Mouse Fly
somite development GO:0061053 96 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
cell proliferation GO:0008283 80 0.022
rna metabolic process GO:0016070 219 0.022
establishment of protein localization to plasma membrane GO:0090002 1 0.022
neurological system process GO:0050877 62 0.022
cell cycle process GO:0022402 53 0.022
Human Mouse Fly
regulation of protein transport GO:0051223 3 0.022
Fly
regulation of protein binding GO:0043393 3 0.022
glucose homeostasis GO:0042593 1 0.022
positive regulation of dna metabolic process GO:0051054 1 0.022
renal tubule morphogenesis GO:0061333 1 0.022
regulation of cell substrate adhesion GO:0010810 1 0.022
cell cycle g2 m phase transition GO:0044839 4 0.021
embryonic skeletal system development GO:0048706 97 0.021
transcription dna templated GO:0006351 181 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
regulation of autophagy GO:0010506 3 0.021
synaptic vesicle localization GO:0097479 1 0.021
regulation of cellular component movement GO:0051270 55 0.021
protein targeting to nucleus GO:0044744 3 0.021
regulation of primary metabolic process GO:0080090 311 0.021
Fly
digestive tract morphogenesis GO:0048546 231 0.021
regulation of gene expression GO:0010468 265 0.021
signal transduction GO:0007165 455 0.020
peptidyl serine modification GO:0018209 2 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
regulation of protein localization to plasma membrane GO:1903076 1 0.020
organism emergence from protective structure GO:0071684 4 0.020
cell substrate junction assembly GO:0007044 2 0.020
epithelial cell differentiation GO:0030855 116 0.020
Human Fly
phagocytosis engulfment GO:0006911 1 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
regulation of reproductive process GO:2000241 4 0.020
negative regulation of neural precursor cell proliferation GO:2000178 1 0.020
intracellular signal transduction GO:0035556 85 0.020
Rat Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
regulation of growth GO:0040008 42 0.020
Fly
mitotic cell cycle process GO:1903047 48 0.020
Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
positive regulation of cell adhesion GO:0045785 1 0.020
cellular response to decreased oxygen levels GO:0036294 1 0.020
synaptic vesicle transport GO:0048489 1 0.020
regulation of locomotion GO:0040012 55 0.019
ribonucleotide metabolic process GO:0009259 27 0.019
heart development GO:0007507 313 0.019
protein complex subunit organization GO:0071822 46 0.019
Fly
axon guidance GO:0007411 86 0.019
nuclear transport GO:0051169 4 0.019
spermatid development GO:0007286 2 0.019
establishment of endothelial barrier GO:0061028 3 0.019
negative regulation of protein complex assembly GO:0031333 1 0.019
protein import into nucleus GO:0006606 3 0.019
negative regulation of biological process GO:0048519 304 0.019
Human Fly
chemotaxis GO:0006935 104 0.019
growth GO:0040007 174 0.019
Fly
nephron morphogenesis GO:0072028 2 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
post embryonic organ development GO:0048569 4 0.018
Fly
lateral inhibition GO:0046331 1 0.018
organophosphate metabolic process GO:0019637 37 0.018
regulation of axonogenesis GO:0050770 32 0.018
Fly
phosphorylation GO:0016310 69 0.018
Human Fly
actomyosin structure organization GO:0031032 53 0.018
Fly
regulation of neuron projection development GO:0010975 40 0.018
Fly
embryonic organ development GO:0048568 381 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
Mouse
negative regulation of catabolic process GO:0009895 3 0.018
cellular macromolecular complex assembly GO:0034622 24 0.018
regulation of phosphate metabolic process GO:0019220 43 0.018
Fly
regulation of wound healing GO:0061041 2 0.018
Fly
skeletal system morphogenesis GO:0048705 102 0.018
oocyte development GO:0048599 14 0.018
Fly
response to abiotic stimulus GO:0009628 122 0.018
sensory perception GO:0007600 39 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
ear development GO:0043583 127 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
regulation of carbohydrate metabolic process GO:0006109 4 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
protein modification process GO:0036211 100 0.018
Human Fly
organic substance biosynthetic process GO:1901576 289 0.018
macroautophagy GO:0016236 1 0.018
regulation of cell differentiation GO:0045595 142 0.018
Human Fly
negative regulation of secretion GO:0051048 2 0.017
regulation of molecular function GO:0065009 70 0.017
cellular protein modification process GO:0006464 100 0.017
Human Fly
cellular component disassembly GO:0022411 1 0.017
embryonic pattern specification GO:0009880 44 0.017
rna biosynthetic process GO:0032774 181 0.017
cellular protein catabolic process GO:0044257 4 0.017
actin filament based process GO:0030029 64 0.017
regulation of transcription dna templated GO:0006355 213 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
positive regulation of epithelial cell differentiation GO:0030858 2 0.017
cellular response to oxygen levels GO:0071453 1 0.017
ribose phosphate metabolic process GO:0019693 27 0.017
nephron epithelium morphogenesis GO:0072088 1 0.016
melanin metabolic process GO:0006582 2 0.016
left right pattern formation GO:0060972 19 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
nuclear import GO:0051170 3 0.016
protein localization to nucleus GO:0034504 3 0.016
regulation of oocyte development GO:0060281 3 0.016
retina development in camera type eye GO:0060041 146 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
catabolic process GO:0009056 32 0.016
regulation of intracellular signal transduction GO:1902531 57 0.016
renal system development GO:0072001 94 0.016
response to nutrient GO:0007584 3 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
carbohydrate homeostasis GO:0033500 1 0.016
wnt signaling pathway GO:0016055 80 0.016
chemosensory behavior GO:0007635 1 0.016
sensory organ morphogenesis GO:0090596 200 0.015
Fly
regulation of mrna processing GO:0050684 3 0.015
response to carbohydrate GO:0009743 3 0.015
camera type eye development GO:0043010 222 0.015
macromolecular complex disassembly GO:0032984 1 0.015
protein dephosphorylation GO:0006470 3 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
cell substrate adherens junction assembly GO:0007045 1 0.015
organic substance catabolic process GO:1901575 28 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
negative regulation of cellular process GO:0048523 283 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
skin development GO:0043588 54 0.015
Human Fly
regulation of jak stat cascade GO:0046425 3 0.015
aromatic compound catabolic process GO:0019439 15 0.015
adherens junction assembly GO:0034333 1 0.015
meiotic nuclear division GO:0007126 4 0.015
neurotransmitter secretion GO:0007269 2 0.015
positive regulation of cell division GO:0051781 2 0.015
response to alkaloid GO:0043279 2 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
polarized epithelial cell differentiation GO:0030859 4 0.015
regulation of cell growth GO:0001558 29 0.015
regulation of dendrite development GO:0050773 3 0.015
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
g2 m transition of mitotic cell cycle GO:0000086 4 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
ion transmembrane transport GO:0034220 91 0.015
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.014
leukocyte homeostasis GO:0001776 2 0.014
amino acid transport GO:0006865 2 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
nucleic acid metabolic process GO:0090304 244 0.014
positive regulation of molecular function GO:0044093 33 0.014
membrane invagination GO:0010324 1 0.014
nucleic acid templated transcription GO:0097659 181 0.014
angiogenesis GO:0001525 158 0.014
Human
positive regulation of notch signaling pathway GO:0045747 3 0.014
motor neuron axon guidance GO:0008045 23 0.014
cognition GO:0050890 1 0.014
bmp signaling pathway GO:0030509 52 0.014
vesicle mediated transport GO:0016192 22 0.014
establishment of localization in cell GO:0051649 77 0.014
Fly
macromolecular complex subunit organization GO:0043933 74 0.014
Fly
cellular response to chemical stimulus GO:0070887 157 0.014
regulation of response to nutrient levels GO:0032107 1 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
Mouse Fly
reactive oxygen species metabolic process GO:0072593 6 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
cell aging GO:0007569 2 0.014
purine nucleotide metabolic process GO:0006163 27 0.014
regulation of programmed cell death GO:0043067 101 0.014
microtubule organizing center organization GO:0031023 1 0.014
Human Mouse
sensory perception of pain GO:0019233 1 0.014
cortical cytoskeleton organization GO:0030865 1 0.013
lamellipodium assembly GO:0030032 1 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
proximal distal pattern formation GO:0009954 1 0.013
protein complex disassembly GO:0043241 1 0.013
cellular response to hypoxia GO:0071456 1 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
detection of abiotic stimulus GO:0009582 24 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of cell maturation GO:1903429 1 0.013
muscle organ development GO:0007517 101 0.013
cellular lipid catabolic process GO:0044242 3 0.013
striated muscle tissue development GO:0014706 110 0.013
single fertilization GO:0007338 3 0.013
mitochondrion organization GO:0007005 4 0.013
sensory perception of mechanical stimulus GO:0050954 16 0.013
positive regulation of metabolic process GO:0009893 108 0.013
response to glucose GO:0009749 3 0.013
epidermal cell differentiation GO:0009913 36 0.013
Human Fly
convergent extension involved in gastrulation GO:0060027 71 0.012
cellular localization GO:0051641 97 0.012
Fly
cellular nitrogen compound catabolic process GO:0044270 15 0.012
somitogenesis GO:0001756 87 0.012
regulation of binding GO:0051098 3 0.012
ion transport GO:0006811 114 0.012
stem cell differentiation GO:0048863 117 0.012
positive regulation of jak stat cascade GO:0046427 2 0.012
determination of bilateral symmetry GO:0009855 204 0.012
Zebrafish
positive regulation of cell activation GO:0050867 1 0.012
positive regulation of cell substrate adhesion GO:0010811 1 0.012
detection of stimulus involved in sensory perception GO:0050906 21 0.012
immune system development GO:0002520 191 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
positive regulation of protein kinase b signaling GO:0051897 1 0.012
ameboidal type cell migration GO:0001667 143 0.012
regulation of protein targeting GO:1903533 2 0.012
exocrine system development GO:0035272 28 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.012
positive regulation of signal transduction GO:0009967 56 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
positive regulation of catalytic activity GO:0043085 25 0.012
cardiac cell fate commitment GO:0060911 1 0.012
gland development GO:0048732 143 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
determination of left right symmetry GO:0007368 179 0.012
Zebrafish
protein secretion GO:0009306 1 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
mesoderm development GO:0007498 88 0.012
regulation of catalytic activity GO:0050790 55 0.012
neuron projection guidance GO:0097485 86 0.012
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.012
regulation of protein phosphorylation GO:0001932 18 0.012
Fly
golgi vesicle transport GO:0048193 3 0.012
regulation of protein kinase b signaling GO:0051896 8 0.012
protein phosphorylation GO:0006468 47 0.012
Human Fly
lymphangiogenesis GO:0001946 25 0.012
protein depolymerization GO:0051261 1 0.012
spermatid differentiation GO:0048515 2 0.012
midbrain development GO:0030901 28 0.012
cellular modified amino acid metabolic process GO:0006575 3 0.012
regulation of mapk cascade GO:0043408 14 0.012
mesenchymal cell proliferation GO:0010463 1 0.012
regulation of anatomical structure size GO:0090066 33 0.012
cellular component maintenance GO:0043954 3 0.012
striated muscle cell differentiation GO:0051146 129 0.012
negative regulation of signaling GO:0023057 96 0.012
homeostatic process GO:0042592 142 0.012
cytoplasm organization GO:0007028 4 0.012
negative regulation of dna replication GO:0008156 2 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.011
regulation of chromosome segregation GO:0051983 1 0.011
protein complex assembly GO:0006461 30 0.011
response to organic substance GO:0010033 153 0.011
regulation of gastrulation GO:0010470 24 0.011
regulation of phosphorus metabolic process GO:0051174 43 0.011
Fly
response to amino acid GO:0043200 2 0.011
membrane lipid biosynthetic process GO:0046467 2 0.011
peptidyl threonine modification GO:0018210 1 0.011

rock2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.141
cardiovascular system disease DOID:1287 0 0.049
nervous system disease DOID:863 0 0.046
disease of metabolism DOID:0014667 0 0.018
myopathy DOID:423 0 0.017
muscular disease DOID:0080000 0 0.017
musculoskeletal system disease DOID:17 0 0.017
muscle tissue disease DOID:66 0 0.017
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013