Danio rerio

0 known processes

rpe65a

retinal pigment epithelium-specific protein 65a

(Aliases: rpepa,MGC73213,zgc:73213)

rpe65a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
retina development in camera type eye GO:0060041 146 0.398
Mouse
eye development GO:0001654 277 0.133
Mouse
melanin metabolic process GO:0006582 2 0.094
sensory organ development GO:0007423 393 0.085
Mouse
detection of abiotic stimulus GO:0009582 24 0.079
Fly
sensory perception of light stimulus GO:0050953 19 0.066
Mouse
signal transduction GO:0007165 455 0.066
Mouse Fly
sensory perception GO:0007600 39 0.063
Mouse
visual perception GO:0007601 17 0.063
Mouse
stem cell proliferation GO:0072089 4 0.061
dopamine metabolic process GO:0042417 2 0.059
small molecule metabolic process GO:0044281 77 0.058
Fly
catecholamine metabolic process GO:0006584 2 0.054
generation of neurons GO:0048699 385 0.053
Mouse
detection of visible light GO:0009584 12 0.049
Fly
camera type eye development GO:0043010 222 0.048
Mouse
cellular component movement GO:0006928 335 0.048
neuron development GO:0048666 262 0.046
Mouse
inorganic anion transport GO:0015698 25 0.044
guanosine containing compound metabolic process GO:1901068 4 0.043
cytokinesis GO:0000910 3 0.040
guanosine containing compound catabolic process GO:1901069 2 0.040
positive regulation of map kinase activity GO:0043406 3 0.040
regulation of signaling GO:0023051 235 0.038
vasculature development GO:0001944 278 0.037
neuronal action potential GO:0019228 18 0.036
inorganic anion transmembrane transport GO:0098661 10 0.036
regulation of cytoplasmic transport GO:1903649 4 0.036
detection of stimulus GO:0051606 29 0.036
Fly
cellular amine metabolic process GO:0044106 2 0.035
angiogenesis GO:0001525 158 0.035
regulation of gtp catabolic process GO:0033124 2 0.034
single organism biosynthetic process GO:0044711 71 0.034
Fly
response to vitamin b3 GO:0033552 2 0.033
response to stress GO:0006950 263 0.033
regulation of cell communication GO:0010646 232 0.032
light absorption GO:0016037 2 0.032
cytoskeleton dependent cytokinesis GO:0061640 3 0.029
tube morphogenesis GO:0035239 349 0.029
organelle organization GO:0006996 227 0.029
negative regulation of sequestering of calcium ion GO:0051283 4 0.029
lipid storage GO:0019915 1 0.028
maintenance of location GO:0051235 4 0.028
response to wounding GO:0009611 116 0.027
cellular component morphogenesis GO:0032989 336 0.026
regulation of biological quality GO:0065008 263 0.026
gtp metabolic process GO:0046039 4 0.026
regulation of nucleotide catabolic process GO:0030811 2 0.026
innate immune response GO:0045087 13 0.026
melanin biosynthetic process GO:0042438 1 0.025
amine metabolic process GO:0009308 2 0.025
response to chemical GO:0042221 320 0.025
Mouse
regulation of sequestering of calcium ion GO:0051282 4 0.024
larval development GO:0002164 2 0.024
cellular ketone metabolic process GO:0042180 11 0.023
pigment metabolic process GO:0042440 12 0.022
Fly
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
regulation of growth rate GO:0040009 1 0.022
negative regulation of cellular process GO:0048523 283 0.021
detection of stimulus involved in sensory perception GO:0050906 21 0.021
inositol lipid mediated signaling GO:0048017 2 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
regulation of gtpase activity GO:0043087 2 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
neuron differentiation GO:0030182 353 0.020
Mouse
regulation of localization GO:0032879 104 0.020
regulation of protein transport GO:0051223 3 0.019
protein modification by small protein removal GO:0070646 1 0.019
catechol containing compound biosynthetic process GO:0009713 2 0.019
pigment biosynthetic process GO:0046148 9 0.019
Fly
developmental programmed cell death GO:0010623 4 0.018
absorption of visible light GO:0016038 2 0.018
neuron fate determination GO:0048664 2 0.018
neuroblast proliferation GO:0007405 2 0.018
vitamin a biosynthetic process GO:0035238 1 0.018
Fly
multicellular organismal signaling GO:0035637 22 0.018
cellular biosynthetic process GO:0044249 286 0.018
Fly
cortical actin cytoskeleton organization GO:0030866 1 0.018
small gtpase mediated signal transduction GO:0007264 8 0.018
detection of external stimulus GO:0009581 24 0.017
Fly
regulation of catalytic activity GO:0050790 55 0.017
gtp catabolic process GO:0006184 2 0.017
sensory organ morphogenesis GO:0090596 200 0.017
Mouse
actin cytoskeleton organization GO:0030036 63 0.017
intracellular signal transduction GO:0035556 85 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
aging GO:0007568 2 0.017
light adaption GO:0036367 1 0.016
regulation of intracellular signal transduction GO:1902531 57 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
stem cell division GO:0017145 1 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.015
morphogenesis of an epithelial sheet GO:0002011 49 0.015
multicellular organismal water homeostasis GO:0050891 1 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
adult behavior GO:0030534 2 0.014
negative regulation of kinase activity GO:0033673 4 0.014
negative regulation of defense response GO:0031348 2 0.014
response to drug GO:0042493 3 0.014
single organism organelle organization GO:1902589 199 0.014
action potential GO:0001508 19 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
Mouse
central nervous system development GO:0007417 387 0.014
eye photoreceptor cell differentiation GO:0001754 45 0.014
neurological system process GO:0050877 62 0.014
Mouse
nucleocytoplasmic transport GO:0006913 4 0.014
regulation of receptor recycling GO:0001919 3 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
response to ketone GO:1901654 1 0.013
transport GO:0006810 220 0.013
optokinetic behavior GO:0007634 9 0.013
establishment of blood brain barrier GO:0060856 2 0.013
rhodopsin mediated signaling pathway GO:0016056 1 0.013
regulation of chemotaxis GO:0050920 18 0.013
response to oxygen containing compound GO:1901700 55 0.013
Mouse
retinoic acid receptor signaling pathway GO:0048384 16 0.013
protein desumoylation GO:0016926 1 0.012
regulation of cell migration GO:0030334 40 0.012
cell division GO:0051301 20 0.012
regulation of cell death GO:0010941 103 0.012
inorganic cation transmembrane transport GO:0098662 50 0.012
dopamine biosynthetic process GO:0042416 2 0.012
cellular component biogenesis GO:0044085 178 0.012
ribose phosphate biosynthetic process GO:0046390 20 0.012
receptor recycling GO:0001881 4 0.012
transmission of nerve impulse GO:0019226 19 0.012
secondary metabolic process GO:0019748 3 0.012
response to vitamin GO:0033273 3 0.012
embryonic skeletal joint morphogenesis GO:0060272 3 0.012
ras protein signal transduction GO:0007265 7 0.012
nitrogen compound metabolic process GO:0006807 319 0.012
localization of cell GO:0051674 244 0.012
mesenchymal cell development GO:0014031 78 0.012
isoprenoid metabolic process GO:0006720 15 0.012
Mouse Fly
camera type eye morphogenesis GO:0048593 108 0.012
Mouse
cell motility GO:0048870 244 0.012
activation of mapk activity GO:0000187 3 0.011
regulation of response to stress GO:0080134 36 0.011
organic acid metabolic process GO:0006082 31 0.011
axon ensheathment GO:0008366 18 0.011
cellular response to radiation GO:0071478 4 0.011
Fly
rho protein signal transduction GO:0007266 5 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
nuclear transport GO:0051169 4 0.011
phosphorus metabolic process GO:0006793 109 0.011
endothelial cell development GO:0001885 12 0.011
phototransduction visible light GO:0007603 2 0.011
Fly
regulation of nucleoside metabolic process GO:0009118 2 0.011
retinal cell programmed cell death GO:0046666 2 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
Mouse
single organism metabolic process GO:0044710 217 0.011
Mouse Fly
regulation of notch signaling pathway GO:0008593 16 0.011
response to organic substance GO:0010033 153 0.010
Mouse
purine containing compound metabolic process GO:0072521 29 0.010
actin filament based process GO:0030029 64 0.010
protein homooligomerization GO:0051260 3 0.010
cell projection morphogenesis GO:0048858 244 0.010

rpe65a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
disease of metabolism DOID:0014667 0 0.020
musculoskeletal system disease DOID:17 0 0.019
eye and adnexa disease DOID:1492 0 0.011
retinitis pigmentosa DOID:10584 0 0.011
sensory system disease DOID:0050155 0 0.011
retinal degeneration DOID:8466 0 0.011
eye disease DOID:5614 0 0.011
retinal disease DOID:5679 0 0.011