Danio rerio

0 known processes

rrm2

ribonucleotide reductase M2 polypeptide

(Aliases: chunp6884,r2,cb111)

rrm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cell cycle GO:0045787 3 0.362
larval development GO:0002164 2 0.238
organelle organization GO:0006996 227 0.194
sensory organ development GO:0007423 393 0.160
embryo development ending in birth or egg hatching GO:0009792 271 0.132
aging GO:0007568 2 0.110
heterocycle metabolic process GO:0046483 290 0.105
nitrogen compound metabolic process GO:0006807 319 0.104
meiotic cell cycle process GO:1903046 3 0.102
regulation of meiotic cell cycle GO:0051445 1 0.099
cytokinesis GO:0000910 3 0.098
regulation of cell shape GO:0008360 1 0.096
guanosine containing compound metabolic process GO:1901068 4 0.095
nucleobase containing compound metabolic process GO:0006139 274 0.090
regulation of protein transport GO:0051223 3 0.087
meiotic nuclear division GO:0007126 4 0.085
stem cell maintenance GO:0019827 4 0.083
programmed cell death GO:0012501 119 0.081
regulation of metabolic process GO:0019222 359 0.079
synaptic growth at neuromuscular junction GO:0051124 2 0.074
locomotion GO:0040011 313 0.074
biosynthetic process GO:0009058 294 0.073
organic cyclic compound metabolic process GO:1901360 301 0.072
regulation of gtp catabolic process GO:0033124 2 0.072
single organism metabolic process GO:0044710 217 0.067
cellular nitrogen compound metabolic process GO:0034641 290 0.067
apoptotic process GO:0006915 116 0.066
gtp metabolic process GO:0046039 4 0.066
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.065
organic substance biosynthetic process GO:1901576 289 0.062
vasculature development GO:0001944 278 0.061
cell morphogenesis involved in differentiation GO:0000904 195 0.060
response to stress GO:0006950 263 0.060
stem cell proliferation GO:0072089 4 0.059
regulation of biological quality GO:0065008 263 0.058
cytoskeleton dependent cytokinesis GO:0061640 3 0.057
single organism transport GO:0044765 206 0.055
nucleic acid metabolic process GO:0090304 244 0.053
axonogenesis GO:0007409 152 0.052
negative regulation of cellular process GO:0048523 283 0.052
g1 s transition of mitotic cell cycle GO:0000082 1 0.051
modification dependent protein catabolic process GO:0019941 3 0.050
positive regulation of transport GO:0051050 2 0.048
guanosine containing compound catabolic process GO:1901069 2 0.047
cellular aromatic compound metabolic process GO:0006725 295 0.047
positive regulation of gtp catabolic process GO:0033126 1 0.047
death GO:0016265 121 0.046
nucleocytoplasmic transport GO:0006913 4 0.046
head development GO:0060322 303 0.046
gtp catabolic process GO:0006184 2 0.046
regulation of cell communication GO:0010646 232 0.046
maintenance of location GO:0051235 4 0.045
positive regulation of gtpase activity GO:0043547 1 0.045
cell morphogenesis GO:0000902 289 0.045
transport GO:0006810 220 0.044
nuclear division GO:0000280 23 0.044
immune system process GO:0002376 241 0.043
mitotic cell cycle GO:0000278 64 0.043
positive regulation of cellular catabolic process GO:0031331 3 0.043
positive regulation of nucleoside metabolic process GO:0045979 1 0.043
cell death GO:0008219 121 0.042
response to wounding GO:0009611 116 0.042
response to external stimulus GO:0009605 264 0.041
cytoskeleton organization GO:0007010 96 0.040
positive regulation of catabolic process GO:0009896 4 0.040
compound eye development GO:0048749 2 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.037
single fertilization GO:0007338 3 0.037
ion transport GO:0006811 114 0.037
regulation of protein ubiquitination GO:0031396 3 0.037
microtubule based movement GO:0007018 33 0.037
dna biosynthetic process GO:0071897 3 0.036
cell surface receptor signaling pathway GO:0007166 325 0.035
nuclear transport GO:0051169 4 0.035
regulation of neurogenesis GO:0050767 87 0.034
endosomal transport GO:0016197 2 0.034
generation of neurons GO:0048699 385 0.034
hematopoietic or lymphoid organ development GO:0048534 191 0.034
immune system development GO:0002520 191 0.034
regulation of rho protein signal transduction GO:0035023 2 0.034
intracellular signal transduction GO:0035556 85 0.034
cellular protein catabolic process GO:0044257 4 0.033
cellular component disassembly GO:0022411 1 0.033
cellular component movement GO:0006928 335 0.032
negative regulation of biological process GO:0048519 304 0.032
ubiquitin dependent protein catabolic process GO:0006511 3 0.032
neuron differentiation GO:0030182 353 0.032
cellular component morphogenesis GO:0032989 336 0.032
phagocytosis GO:0006909 3 0.031
rna metabolic process GO:0016070 219 0.031
organelle localization GO:0051640 49 0.031
aromatic compound biosynthetic process GO:0019438 217 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
multicellular organism growth GO:0035264 4 0.030
cellular response to stress GO:0033554 62 0.030
gene expression GO:0010467 252 0.030
cellular component biogenesis GO:0044085 178 0.030
eye development GO:0001654 277 0.029
single organism organelle organization GO:1902589 199 0.029
establishment of localization GO:0051234 244 0.029
localization of cell GO:0051674 244 0.029
cellular component assembly GO:0022607 170 0.029
regulation of cell differentiation GO:0045595 142 0.029
cell migration GO:0016477 237 0.029
positive regulation of nucleotide catabolic process GO:0030813 1 0.029
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
regulation of developmental process GO:0050793 247 0.028
wound healing GO:0042060 90 0.028
regeneration GO:0031099 91 0.028
cell cycle g1 s phase transition GO:0044843 1 0.028
negative regulation of dna metabolic process GO:0051053 4 0.028
regulation of cell cycle GO:0051726 52 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
regulation of cytoplasmic transport GO:1903649 4 0.027
regulation of dna replication GO:0006275 3 0.027
single organism localization GO:1902578 225 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
neuron projection morphogenesis GO:0048812 161 0.027
regulation of purine nucleotide catabolic process GO:0033121 2 0.027
stem cell division GO:0017145 1 0.027
regulation of stem cell proliferation GO:0072091 2 0.026
embryonic organ development GO:0048568 381 0.026
protein complex disassembly GO:0043241 1 0.026
positive regulation of stem cell proliferation GO:2000648 1 0.025
signal transduction GO:0007165 455 0.025
organelle assembly GO:0070925 110 0.025
single organism nuclear import GO:1902593 3 0.025
cellular localization GO:0051641 97 0.025
non recombinational repair GO:0000726 2 0.025
protein polymerization GO:0051258 4 0.024
hindbrain development GO:0030902 91 0.024
regulation of nucleotide catabolic process GO:0030811 2 0.024
angiogenesis GO:0001525 158 0.024
epithelial cell morphogenesis GO:0003382 2 0.024
response to abiotic stimulus GO:0009628 122 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
amine metabolic process GO:0009308 2 0.024
carbohydrate derivative metabolic process GO:1901135 61 0.024
regulation of biosynthetic process GO:0009889 250 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
protein metabolic process GO:0019538 183 0.023
regulation of intracellular protein transport GO:0033157 3 0.023
phosphorus metabolic process GO:0006793 109 0.022
cell cycle GO:0007049 93 0.022
tissue regeneration GO:0042246 74 0.022
spindle assembly GO:0051225 2 0.022
regulation of cell projection organization GO:0031344 44 0.022
regulation of synapse organization GO:0050807 3 0.022
phagocytosis engulfment GO:0006911 1 0.022
heterocycle biosynthetic process GO:0018130 215 0.022
mitotic cell cycle process GO:1903047 48 0.022
cell cycle process GO:0022402 53 0.022
inorganic ion transmembrane transport GO:0098660 57 0.022
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
fertilization GO:0009566 3 0.021
camera type eye development GO:0043010 222 0.021
positive regulation of ras gtpase activity GO:0032320 1 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
regulation of protein catabolic process GO:0042176 1 0.021
tissue remodeling GO:0048771 4 0.021
protein targeting to nucleus GO:0044744 3 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.021
gland development GO:0048732 143 0.021
regulation of signaling GO:0023051 235 0.021
response to nutrient GO:0007584 3 0.021
response to glucose GO:0009749 3 0.021
regulation of establishment of protein localization GO:0070201 4 0.020
digestive system development GO:0055123 289 0.020
cellular amine metabolic process GO:0044106 2 0.020
regulation of mrna processing GO:0050684 3 0.020
response to chemical GO:0042221 320 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.020
ribonucleotide metabolic process GO:0009259 27 0.020
double strand break repair GO:0006302 3 0.020
regulation of muscle contraction GO:0006937 3 0.020
regulation of gtpase activity GO:0043087 2 0.019
sex determination GO:0007530 1 0.019
actin mediated cell contraction GO:0070252 1 0.019
macromolecular complex assembly GO:0065003 35 0.019
nucleic acid templated transcription GO:0097659 181 0.019
axon development GO:0061564 166 0.019
regulation of organ growth GO:0046620 3 0.019
retina development in camera type eye GO:0060041 146 0.019
regulation of protein targeting GO:1903533 2 0.019
mitotic dna damage checkpoint GO:0044773 4 0.019
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.019
cell projection morphogenesis GO:0048858 244 0.019
brain development GO:0007420 293 0.019
protein homooligomerization GO:0051260 3 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
protein import into nucleus GO:0006606 3 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
regulation of cellular metabolic process GO:0031323 320 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
lipid storage GO:0019915 1 0.018
cellular response to external stimulus GO:0071496 2 0.018
ras protein signal transduction GO:0007265 7 0.018
regulation of programmed cell death GO:0043067 101 0.018
nuclear import GO:0051170 3 0.018
meiosis i GO:0007127 1 0.018
protein secretion GO:0009306 1 0.018
small gtpase mediated signal transduction GO:0007264 8 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
rna transport GO:0050658 2 0.018
g2 m transition of mitotic cell cycle GO:0000086 4 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.018
protein depolymerization GO:0051261 1 0.017
small molecule metabolic process GO:0044281 77 0.017
negative regulation of cell communication GO:0010648 96 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
cell part morphogenesis GO:0032990 246 0.017
regulation of signal transduction GO:0009966 225 0.017
protein import GO:0017038 3 0.017
ion transmembrane transport GO:0034220 91 0.017
protein modification process GO:0036211 100 0.017
regulation of response to stimulus GO:0048583 269 0.017
tube morphogenesis GO:0035239 349 0.017
actin cytoskeleton organization GO:0030036 63 0.017
macromolecular complex disassembly GO:0032984 1 0.017
positive regulation of cell division GO:0051781 2 0.016
central nervous system development GO:0007417 387 0.016
regulation of chromosome segregation GO:0051983 1 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
nucleotide metabolic process GO:0009117 28 0.016
regulation of axonogenesis GO:0050770 32 0.016
response to topologically incorrect protein GO:0035966 2 0.016
regulation of nervous system development GO:0051960 90 0.016
neuron projection development GO:0031175 180 0.016
regulation of striated muscle contraction GO:0006942 2 0.016
membrane invagination GO:0010324 1 0.016
cognition GO:0050890 1 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
organelle fusion GO:0048284 3 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
cell cycle g2 m phase transition GO:0044839 4 0.016
cellular response to reactive oxygen species GO:0034614 2 0.016
cell substrate adhesion GO:0031589 4 0.016
neuron development GO:0048666 262 0.016
protein localization to nucleus GO:0034504 3 0.016
positive regulation of cell activation GO:0050867 1 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
g2 dna damage checkpoint GO:0031572 3 0.015
developmental growth GO:0048589 166 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
chromosome segregation GO:0007059 12 0.015
regulation of microtubule cytoskeleton organization GO:0070507 3 0.015
positive regulation of biological process GO:0048518 253 0.015
neuroblast proliferation GO:0007405 2 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
somatic muscle development GO:0007525 4 0.015
regulation of ras gtpase activity GO:0032318 2 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
lymphocyte proliferation GO:0046651 1 0.014
organophosphate metabolic process GO:0019637 37 0.014
establishment of organelle localization GO:0051656 45 0.014
microtubule depolymerization GO:0007019 1 0.014
biological adhesion GO:0022610 40 0.014
microtubule polymerization GO:0046785 2 0.014
cell projection organization GO:0030030 284 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
antimicrobial humoral response GO:0019730 2 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.014
regulation of primary metabolic process GO:0080090 311 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
notochord development GO:0030903 54 0.014
regulation of cell activation GO:0050865 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
leukocyte proliferation GO:0070661 1 0.013
response to monosaccharide GO:0034284 3 0.013
mesenchyme development GO:0060485 127 0.013
muscle cell differentiation GO:0042692 139 0.013
glial cell migration GO:0008347 3 0.013
regulation of dendrite development GO:0050773 3 0.013
double strand break repair via nonhomologous end joining GO:0006303 1 0.013
purine containing compound metabolic process GO:0072521 29 0.013
digestive tract development GO:0048565 265 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
nucleic acid transport GO:0050657 2 0.013
homeostatic process GO:0042592 142 0.013
rho protein signal transduction GO:0007266 5 0.013
regulation of blood vessel size GO:0050880 2 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
response to vitamin GO:0033273 3 0.013
spindle assembly involved in mitosis GO:0090307 1 0.013
regulation of catalytic activity GO:0050790 55 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
regulation of cell death GO:0010941 103 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
anion transport GO:0006820 38 0.012
regulation of metal ion transport GO:0010959 4 0.012
regulation of reproductive process GO:2000241 4 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
chordate embryonic development GO:0043009 271 0.012
actin filament based movement GO:0030048 1 0.012
regulation of binding GO:0051098 3 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
muscle structure development GO:0061061 196 0.012
cortical cytoskeleton organization GO:0030865 1 0.012
gastrulation GO:0007369 208 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
sequestering of metal ion GO:0051238 3 0.012
atp catabolic process GO:0006200 4 0.012
actin filament based process GO:0030029 64 0.012
exocytosis GO:0006887 1 0.012
regulation of cell morphogenesis GO:0022604 42 0.012
protein polyubiquitination GO:0000209 4 0.012
cellular response to topologically incorrect protein GO:0035967 2 0.012
negative regulation of wnt signaling pathway GO:0030178 30 0.012
cell motility GO:0048870 244 0.012
cellular biosynthetic process GO:0044249 286 0.012
mitotic cytokinesis GO:0000281 3 0.012
regulation of neuron projection development GO:0010975 40 0.012
regulation of neuron differentiation GO:0045664 56 0.012
negative regulation of chromosome organization GO:2001251 1 0.011
mesoderm development GO:0007498 88 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
response to organic substance GO:0010033 153 0.011
mesenchymal cell proliferation GO:0010463 1 0.011
rna biosynthetic process GO:0032774 181 0.011
regulation of inflammatory response GO:0050727 2 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
rna 3 end processing GO:0031123 2 0.011
positive regulation of cell death GO:0010942 29 0.011
epithelial cell differentiation GO:0030855 116 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
apical junction assembly GO:0043297 1 0.011
phosphorylation GO:0016310 69 0.011
response to metal ion GO:0010038 34 0.011
protein heterooligomerization GO:0051291 1 0.011
cellular ketone metabolic process GO:0042180 11 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
cellular response to radiation GO:0071478 4 0.011
response to virus GO:0009615 21 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
reproduction GO:0000003 40 0.011
cellular response to nutrient levels GO:0031669 2 0.011
positive regulation of cellular process GO:0048522 201 0.011
negative regulation of signal transduction GO:0009968 94 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
cytokinetic process GO:0032506 2 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
transcription dna templated GO:0006351 181 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
ameboidal type cell migration GO:0001667 143 0.011
regulation of mitotic cell cycle GO:0007346 25 0.011
regulation of apoptotic process GO:0042981 98 0.011
behavior GO:0007610 74 0.011
positive regulation of map kinase activity GO:0043406 3 0.010
regulation of cell development GO:0060284 100 0.010
response to inorganic substance GO:0010035 38 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
inner ear development GO:0048839 126 0.010
carbohydrate homeostasis GO:0033500 1 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
cellular response to starvation GO:0009267 1 0.010
blood vessel development GO:0001568 246 0.010
fin regeneration GO:0031101 51 0.010

rrm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
disease of cellular proliferation DOID:14566 0 0.015
disease of metabolism DOID:0014667 0 0.015
nervous system disease DOID:863 0 0.011
cancer DOID:162 0 0.011