Danio rerio

0 known processes

rxraa

retinoid X receptor, alpha a

(Aliases: RXRalpha-B)

rxraa biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
retinoic acid receptor signaling pathway GO:0048384 16 0.891
Human Zebrafish Mouse
cellular response to lipopolysaccharide GO:0071222 3 0.657
neuron differentiation GO:0030182 353 0.656
Rat
eye morphogenesis GO:0048592 144 0.627
eye photoreceptor cell differentiation GO:0001754 45 0.614
eye development GO:0001654 277 0.607
Mouse
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.587
Zebrafish
embryonic organ development GO:0048568 381 0.513
rna biosynthetic process GO:0032774 181 0.500
Human Zebrafish Mouse Rat Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.481
Human Zebrafish Mouse Rat Worm
heart development GO:0007507 313 0.458
Mouse
signal transduction GO:0007165 455 0.455
Human Zebrafish Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.450
Human Zebrafish Mouse Rat Worm
sensory organ development GO:0007423 393 0.444
Mouse
connective tissue development GO:0061448 99 0.403
lymphatic endothelial cell fate commitment GO:0060838 1 0.391
Zebrafish
eye photoreceptor cell development GO:0042462 30 0.390
blood vessel morphogenesis GO:0048514 216 0.389
regulation of metabolic process GO:0019222 359 0.384
Human Zebrafish Mouse Rat Worm
nucleobase containing compound metabolic process GO:0006139 274 0.381
Human Zebrafish Mouse Rat Worm
skeletal system development GO:0001501 181 0.367
retinal cone cell development GO:0046549 8 0.362
regulation of multicellular organismal development GO:2000026 223 0.358
Mouse Rat
digestive system development GO:0055123 289 0.345
Rat
sensory organ morphogenesis GO:0090596 200 0.343
generation of neurons GO:0048699 385 0.324
Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.315
Human Zebrafish Mouse Rat Worm
response to chemical GO:0042221 320 0.314
Human Zebrafish Mouse Rat
regulation of nervous system development GO:0051960 90 0.312
Rat
heterocycle metabolic process GO:0046483 290 0.309
Human Zebrafish Mouse Rat Worm
digestive tract development GO:0048565 265 0.305
Rat
biosynthetic process GO:0009058 294 0.304
Human Zebrafish Mouse Rat Worm
cellular biosynthetic process GO:0044249 286 0.286
Human Zebrafish Mouse Rat Worm
vasculature development GO:0001944 278 0.281
Zebrafish
neuron development GO:0048666 262 0.278
Rat
organic substance biosynthetic process GO:1901576 289 0.253
Human Zebrafish Mouse Rat Worm
neural retina development GO:0003407 49 0.252
cellular response to lipid GO:0071396 39 0.248
small molecule metabolic process GO:0044281 77 0.247
Worm
camera type eye photoreceptor cell differentiation GO:0060219 19 0.244
brain development GO:0007420 293 0.242
cellular macromolecule biosynthetic process GO:0034645 224 0.237
Human Zebrafish Mouse Rat Worm
regulation of developmental process GO:0050793 247 0.235
Mouse Rat
retina morphogenesis in camera type eye GO:0060042 79 0.229
cellular aromatic compound metabolic process GO:0006725 295 0.227
Human Zebrafish Mouse Rat Worm
lipid storage GO:0019915 1 0.225
Worm
larval development GO:0002164 2 0.219
Worm
embryonic limb morphogenesis GO:0030326 2 0.217
positive regulation of transcription dna templated GO:0045893 57 0.216
Human Zebrafish Mouse Worm
stem cell division GO:0017145 1 0.214
heterocycle biosynthetic process GO:0018130 215 0.204
Human Zebrafish Mouse Rat Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.203
Human Zebrafish Mouse
head development GO:0060322 303 0.201
retina development in camera type eye GO:0060041 146 0.197
transport GO:0006810 220 0.194
Worm
intracellular receptor signaling pathway GO:0030522 30 0.192
Human Zebrafish Mouse
positive regulation of rna metabolic process GO:0051254 59 0.190
Human Zebrafish Mouse Worm
lymphatic endothelial cell differentiation GO:0060836 1 0.187
Zebrafish
lymph vessel development GO:0001945 27 0.186
Zebrafish
neuroblast proliferation GO:0007405 2 0.185
embryo development ending in birth or egg hatching GO:0009792 271 0.180
Mouse Worm
cellular ketone metabolic process GO:0042180 11 0.174
Worm
organic cyclic compound metabolic process GO:1901360 301 0.174
Human Zebrafish Mouse Rat Worm
circadian regulation of gene expression GO:0032922 8 0.170
cell fate commitment GO:0045165 99 0.170
Zebrafish
photoreceptor cell differentiation GO:0046530 55 0.166
cellular response to molecule of bacterial origin GO:0071219 3 0.166
positive regulation of cellular biosynthetic process GO:0031328 68 0.165
Human Zebrafish Mouse Worm
transcription from rna polymerase iii promoter GO:0006383 1 0.163
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.161
Human Zebrafish Mouse Rat Worm
response to ketone GO:1901654 1 0.160
cartilage development GO:0051216 96 0.160
negative regulation of bmp signaling pathway GO:0030514 13 0.159
endothelial cell fate commitment GO:0060839 3 0.158
Zebrafish
mesoderm development GO:0007498 88 0.155
tissue remodeling GO:0048771 4 0.152
organic cyclic compound biosynthetic process GO:1901362 223 0.151
Human Zebrafish Mouse Rat Worm
nucleic acid templated transcription GO:0097659 181 0.150
Human Zebrafish Mouse Rat Worm
regulation of primary metabolic process GO:0080090 311 0.149
Human Zebrafish Mouse Rat Worm
organic acid metabolic process GO:0006082 31 0.149
Worm
positive regulation of biosynthetic process GO:0009891 68 0.149
Human Zebrafish Mouse Worm
macromolecule biosynthetic process GO:0009059 227 0.147
Human Zebrafish Mouse Rat Worm
bmp signaling pathway GO:0030509 52 0.145
cellular nitrogen compound metabolic process GO:0034641 290 0.144
Human Zebrafish Mouse Rat Worm
single fertilization GO:0007338 3 0.143
epithelial cell differentiation GO:0030855 116 0.143
Zebrafish Mouse
regulation of signaling GO:0023051 235 0.138
regulation of cellular biosynthetic process GO:0031326 245 0.136
Human Zebrafish Mouse Rat Worm
central nervous system development GO:0007417 387 0.135
regulation of gene expression GO:0010468 265 0.135
Human Zebrafish Mouse Rat Worm
transcription dna templated GO:0006351 181 0.134
Human Zebrafish Mouse Rat Worm
regulation of biosynthetic process GO:0009889 250 0.133
Human Zebrafish Mouse Rat Worm
regulation of synapse assembly GO:0051963 3 0.132
immune system process GO:0002376 241 0.129
regulation of fatty acid metabolic process GO:0019217 1 0.127
Worm
heart morphogenesis GO:0003007 156 0.126
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.126
angiogenesis GO:0001525 158 0.126
septum transversum development GO:0003343 4 0.124
sensory perception of chemical stimulus GO:0007606 3 0.123
cellular response to organic substance GO:0071310 105 0.121
Rat
single organism metabolic process GO:0044710 217 0.121
Worm
determination of heart left right asymmetry GO:0061371 117 0.120
aromatic compound biosynthetic process GO:0019438 217 0.120
Human Zebrafish Mouse Rat Worm
regulation of biological quality GO:0065008 263 0.120
Human Worm
stem cell differentiation GO:0048863 117 0.119
hemopoiesis GO:0030097 183 0.115
chordate embryonic development GO:0043009 271 0.113
Mouse
anterior posterior pattern specification GO:0009952 152 0.112
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.111
Human Zebrafish Mouse Worm
morphogenesis of an epithelium GO:0002009 333 0.110
Mouse
retinal cone cell differentiation GO:0042670 12 0.110
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.110
Human Zebrafish Mouse Worm
response to organic substance GO:0010033 153 0.109
Human Zebrafish Rat
lateral mesoderm development GO:0048368 23 0.107
positive regulation of transport GO:0051050 2 0.105
regulation of macromolecule metabolic process GO:0060255 317 0.104
Human Zebrafish Mouse Rat Worm
growth GO:0040007 174 0.102
Mouse
camera type eye development GO:0043010 222 0.101
Mouse
lymphangiogenesis GO:0001946 25 0.100
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 7 0.099
Worm
regulation of cellular metabolic process GO:0031323 320 0.097
Human Zebrafish Mouse Rat Worm
immune system development GO:0002520 191 0.095
regulation of transcription dna templated GO:0006355 213 0.095
Human Zebrafish Mouse Rat Worm
rna metabolic process GO:0016070 219 0.094
Human Zebrafish Mouse Rat Worm
oxoacid metabolic process GO:0043436 31 0.094
Worm
cellular response to retinoic acid GO:0071300 1 0.093
cellular response to chemical stimulus GO:0070887 157 0.093
Mouse Rat
regulation of cell communication GO:0010646 232 0.093
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.093
regulation of synapse organization GO:0050807 3 0.091
nucleic acid metabolic process GO:0090304 244 0.091
Human Zebrafish Mouse Rat Worm
cellular component movement GO:0006928 335 0.090
specification of symmetry GO:0009799 204 0.090
response to organic cyclic compound GO:0014070 51 0.090
Rat
regulation of bmp signaling pathway GO:0030510 39 0.089
response to retinoic acid GO:0032526 6 0.088
Human Zebrafish Rat
response to biotic stimulus GO:0009607 97 0.086
response to acid chemical GO:0001101 17 0.086
Human Zebrafish Rat
homeostatic process GO:0042592 142 0.086
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.085
Human Zebrafish Mouse Worm
blood vessel development GO:0001568 246 0.084
positive regulation of nucleic acid templated transcription GO:1903508 57 0.084
Human Zebrafish Mouse Worm
negative regulation of biosynthetic process GO:0009890 55 0.083
Human Zebrafish Mouse
cellular response to biotic stimulus GO:0071216 3 0.083
outflow tract morphogenesis GO:0003151 1 0.082
mesenchyme development GO:0060485 127 0.082
regulation of localization GO:0032879 104 0.081
regionalization GO:0003002 274 0.081
negative regulation of nucleic acid templated transcription GO:1903507 45 0.080
Human Zebrafish Mouse
regulation of signal transduction GO:0009966 225 0.080
gland development GO:0048732 143 0.079
Mouse Rat
positive regulation of cellular process GO:0048522 201 0.079
Human Zebrafish Mouse Rat Worm
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.078
negative regulation of cell differentiation GO:0045596 46 0.078
epithelial tube morphogenesis GO:0060562 148 0.077
cellular nitrogen compound biosynthetic process GO:0044271 218 0.077
Human Zebrafish Mouse Rat Worm
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.076
cellular amino acid metabolic process GO:0006520 7 0.076
negative regulation of neuron projection development GO:0010977 9 0.075
neurological system process GO:0050877 62 0.075
camera type eye morphogenesis GO:0048593 108 0.074
establishment of localization GO:0051234 244 0.073
Worm
maintenance of location GO:0051235 4 0.073
Worm
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.073
response to oxygen containing compound GO:1901700 55 0.072
Human Zebrafish Rat
carboxylic acid metabolic process GO:0019752 22 0.071
Worm
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.071
cardiac muscle cell differentiation GO:0055007 30 0.069
Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.069
regulation of nitrogen compound metabolic process GO:0051171 251 0.069
Human Zebrafish Mouse Rat Worm
determination of bilateral symmetry GO:0009855 204 0.068
neuronal action potential GO:0019228 18 0.068
negative regulation of gene expression GO:0010629 65 0.068
Human Zebrafish Mouse
negative regulation of biological process GO:0048519 304 0.066
Human Zebrafish Mouse Rat
cell substrate adhesion GO:0031589 4 0.066
endochondral bone growth GO:0003416 2 0.066
skeletal muscle tissue development GO:0007519 67 0.065
positive regulation of rna biosynthetic process GO:1902680 57 0.064
Human Zebrafish Mouse Worm
growth plate cartilage development GO:0003417 2 0.064
embryonic heart tube development GO:0035050 133 0.064
renal system development GO:0072001 94 0.062
nucleocytoplasmic transport GO:0006913 4 0.062
nuclear transport GO:0051169 4 0.061
intrahepatic bile duct development GO:0035622 11 0.061
pharyngeal system development GO:0060037 18 0.061
kidney development GO:0001822 92 0.061
cell proliferation GO:0008283 80 0.060
Mouse Rat
pronephros morphogenesis GO:0072114 14 0.060
muscle fiber development GO:0048747 52 0.059
determination of left right symmetry GO:0007368 179 0.059
stem cell proliferation GO:0072089 4 0.059
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.059
regulation of dendrite development GO:0050773 3 0.059
phagocytosis GO:0006909 3 0.058
hair cell differentiation GO:0035315 32 0.057
positive regulation of cellular metabolic process GO:0031325 94 0.057
Human Zebrafish Mouse Worm
negative regulation of cellular biosynthetic process GO:0031327 55 0.057
Human Zebrafish Mouse
photoreceptor cell development GO:0042461 40 0.057
stem cell maintenance GO:0019827 4 0.056
response to lipid GO:0033993 60 0.055
Human Zebrafish Rat
system process GO:0003008 185 0.055
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.055
Human Zebrafish Mouse
biomineral tissue development GO:0031214 13 0.055
organophosphate metabolic process GO:0019637 37 0.055
retinal rod cell development GO:0046548 4 0.055
regulation of rna biosynthetic process GO:2001141 213 0.054
Human Zebrafish Mouse Rat Worm
regulation of bone mineralization GO:0030500 2 0.054
cellular amino acid biosynthetic process GO:0008652 2 0.054
regulation of embryonic development GO:0045995 47 0.053
regulation of cytoplasmic transport GO:1903649 4 0.053
cell projection organization GO:0030030 284 0.052
Rat
lymph vessel morphogenesis GO:0036303 25 0.052
Zebrafish
mesenchymal cell differentiation GO:0048762 87 0.050
cellular component assembly GO:0022607 170 0.050
Human
enzyme linked receptor protein signaling pathway GO:0007167 106 0.050
response to external stimulus GO:0009605 264 0.050
Rat
regulation of multicellular organismal process GO:0051239 277 0.050
Mouse Rat
striated muscle tissue development GO:0014706 110 0.050
Mouse
aging GO:0007568 2 0.049
Rat Worm
fertilization GO:0009566 3 0.049
regulation of intracellular protein transport GO:0033157 3 0.049
regulation of chondrocyte differentiation GO:0032330 1 0.048
muscle tissue development GO:0060537 110 0.048
Mouse
muscle organ development GO:0007517 101 0.048
Mouse
determination of digestive tract left right asymmetry GO:0071907 10 0.048
positive regulation of cell proliferation GO:0008284 15 0.048
locomotion GO:0040011 313 0.047
Worm
regulation of cell differentiation GO:0045595 142 0.047
response to stress GO:0006950 263 0.047
Rat
axon ensheathment GO:0008366 18 0.046
Rat
urogenital system development GO:0001655 97 0.046
Mouse
fin development GO:0033333 77 0.045
segmentation GO:0035282 97 0.045
single organism organelle organization GO:1902589 199 0.045
response to external biotic stimulus GO:0043207 97 0.045
tube closure GO:0060606 1 0.045
chondrocyte development GO:0002063 4 0.045
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.044
Human Zebrafish Mouse Worm
protein complex subunit organization GO:0071822 46 0.044
Human
positive regulation of striated muscle tissue development GO:0045844 1 0.044
morphogenesis of an epithelial fold GO:0060571 1 0.043
lipid homeostasis GO:0055088 3 0.043
hindbrain development GO:0030902 91 0.043
regulation of response to stimulus GO:0048583 269 0.043
ribonucleotide metabolic process GO:0009259 27 0.043
endoderm development GO:0007492 49 0.042
regulation of rna metabolic process GO:0051252 224 0.042
Human Zebrafish Mouse Rat Worm
liver development GO:0001889 96 0.042
Rat
pronuclear migration GO:0035046 1 0.042
negative regulation of axonogenesis GO:0050771 7 0.042
negative regulation of rna biosynthetic process GO:1902679 45 0.042
Human Zebrafish Mouse
response to other organism GO:0051707 97 0.042
regulation of stem cell proliferation GO:0072091 2 0.042
embryonic organ morphogenesis GO:0048562 274 0.041
single organism reproductive process GO:0044702 40 0.041
Mouse Rat
cellular amine metabolic process GO:0044106 2 0.041
axon development GO:0061564 166 0.041
Rat
pronephros development GO:0048793 69 0.041
gene expression GO:0010467 252 0.040
Human Zebrafish Mouse Rat Worm
regulation of protein transport GO:0051223 3 0.040
determination of pancreatic left right asymmetry GO:0035469 11 0.040
cellular macromolecule metabolic process GO:0044260 391 0.040
Human Zebrafish Mouse Rat Worm
morphogenesis of embryonic epithelium GO:0016331 30 0.039
regulation of macromolecule biosynthetic process GO:0010556 225 0.039
Human Zebrafish Mouse Rat Worm
peptide transport GO:0015833 1 0.038
sprouting angiogenesis GO:0002040 53 0.038
post embryonic organ development GO:0048569 4 0.037
negative regulation of metabolic process GO:0009892 86 0.037
Human Zebrafish Mouse
positive regulation of gene expression GO:0010628 71 0.037
Human Zebrafish Mouse Worm
transmission of nerve impulse GO:0019226 19 0.037
chemosensory behavior GO:0007635 1 0.036
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.036
negative regulation of transcription dna templated GO:0045892 45 0.035
Human Zebrafish Mouse
neural crest cell development GO:0014032 62 0.035
positive regulation of biological process GO:0048518 253 0.035
Human Zebrafish Mouse Rat Worm
transcription from rna polymerase ii promoter GO:0006366 80 0.035
Human Zebrafish Mouse Worm
embryonic hemopoiesis GO:0035162 53 0.035
protein import GO:0017038 3 0.035
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.034
Human Zebrafish Mouse Rat Worm
hormone secretion GO:0046879 2 0.034
heart jogging GO:0003146 40 0.034
developmental growth GO:0048589 166 0.034
neural crest cell migration GO:0001755 42 0.034
phosphorus metabolic process GO:0006793 109 0.034
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.033
Human Zebrafish Mouse
cellular component biogenesis GO:0044085 178 0.033
Human
positive regulation of muscle organ development GO:0048636 1 0.033
multi organism process GO:0051704 134 0.033
Human Mouse Rat
regulation of oocyte development GO:0060281 3 0.033
negative regulation of protein kinase activity GO:0006469 4 0.032
ear development GO:0043583 127 0.032
phosphate containing compound metabolic process GO:0006796 108 0.032
regulation of anatomical structure morphogenesis GO:0022603 130 0.032
Mouse
pericardium morphogenesis GO:0003344 1 0.032
cellular component morphogenesis GO:0032989 336 0.032
response to nutrient GO:0007584 3 0.032
Rat
negative regulation of cellular process GO:0048523 283 0.032
Human Zebrafish Mouse Rat
response to endogenous stimulus GO:0009719 83 0.031
Rat
positive regulation of signaling GO:0023056 56 0.031
regulation of biomineral tissue development GO:0070167 2 0.031
carbohydrate derivative metabolic process GO:1901135 61 0.031
positive regulation of secretion by cell GO:1903532 1 0.031
cell part morphogenesis GO:0032990 246 0.031
lipid metabolic process GO:0006629 52 0.031
Worm
common bile duct development GO:0061009 13 0.031
protein import into nucleus GO:0006606 3 0.031
regulation of heart contraction GO:0008016 32 0.031
macromolecule localization GO:0033036 54 0.031
Worm
regulation of neuron differentiation GO:0045664 56 0.030
regulation of cellular component organization GO:0051128 86 0.030
regulation of cell matrix adhesion GO:0001952 1 0.030
heart process GO:0003015 71 0.030
proepicardium development GO:0003342 4 0.030
epithelial cell development GO:0002064 42 0.029
notochord cell differentiation GO:0060034 18 0.029
cell matrix adhesion GO:0007160 4 0.028
determination of liver left right asymmetry GO:0071910 11 0.028
negative regulation of multicellular organismal process GO:0051241 69 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
dorsal ventral pattern formation GO:0009953 125 0.028
cellular response to stress GO:0033554 62 0.028
Rat
protein targeting to nucleus GO:0044744 3 0.028
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
Human Zebrafish Mouse
skeletal system morphogenesis GO:0048705 102 0.028
cellular response to hormone stimulus GO:0032870 39 0.027
Rat
immune response GO:0006955 28 0.027
translational initiation GO:0006413 3 0.027
Mouse
cell adhesion GO:0007155 40 0.027
embryonic camera type eye development GO:0031076 29 0.027
synaptic target recognition GO:0008039 1 0.027
regulation of organ morphogenesis GO:2000027 35 0.027
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.027
positive regulation of cell cycle GO:0045787 3 0.026
positive regulation of response to stimulus GO:0048584 80 0.026
negative regulation of neurogenesis GO:0050768 20 0.026
negative regulation of rna metabolic process GO:0051253 48 0.026
Human Zebrafish Mouse
positive regulation of multicellular organismal process GO:0051240 52 0.026
kidney epithelium development GO:0072073 23 0.026
negative regulation of developmental process GO:0051093 65 0.026
localization of cell GO:0051674 244 0.026
cell fate specification GO:0001708 68 0.026
positive regulation of muscle tissue development GO:1901863 1 0.025
retinal ganglion cell axon guidance GO:0031290 35 0.025
skeletal muscle organ development GO:0060538 78 0.025
behavior GO:0007610 74 0.025
positive regulation of translation GO:0045727 1 0.025
Mouse
gastrulation GO:0007369 208 0.025
macromolecular complex subunit organization GO:0043933 74 0.025
Human
establishment of protein localization to organelle GO:0072594 4 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
reproduction GO:0000003 40 0.025
Mouse Worm
positive regulation of stem cell proliferation GO:2000648 1 0.025
cellular response to oxygen levels GO:0071453 1 0.025
nuclear import GO:0051170 3 0.025
central nervous system neuron differentiation GO:0021953 74 0.024
response to hormone GO:0009725 48 0.024
Rat
regulation of nucleocytoplasmic transport GO:0046822 2 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
cranial nerve development GO:0021545 42 0.024
ameboidal type cell migration GO:0001667 143 0.024
inner ear development GO:0048839 126 0.024
positive regulation of cytokine production GO:0001819 2 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
regulation of tissue remodeling GO:0034103 2 0.023
erythrocyte homeostasis GO:0034101 55 0.023
regulation of receptor activity GO:0010469 2 0.023
convergent extension GO:0060026 118 0.023
appendage development GO:0048736 80 0.023
muscle structure development GO:0061061 196 0.023
Mouse
multicellular organismal macromolecule metabolic process GO:0044259 2 0.023
cell morphogenesis GO:0000902 289 0.023
endothelium development GO:0003158 25 0.023
Zebrafish
endodermal cell differentiation GO:0035987 19 0.022
response to molecule of bacterial origin GO:0002237 14 0.022
embryonic eye morphogenesis GO:0048048 30 0.022
limb bud formation GO:0060174 2 0.021
sensory perception GO:0007600 39 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
pancreas development GO:0031016 84 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
cytoskeleton organization GO:0007010 96 0.021
somite development GO:0061053 96 0.021
cellular localization GO:0051641 97 0.021
peripheral nervous system neuron differentiation GO:0048934 28 0.021
formation of primary germ layer GO:0001704 62 0.021
intracellular signal transduction GO:0035556 85 0.020
regulation of cartilage development GO:0061035 7 0.020
cellular response to oxygen containing compound GO:1901701 20 0.020
Rat
guanosine containing compound metabolic process GO:1901068 4 0.020
limb development GO:0060173 8 0.020
cell differentiation in spinal cord GO:0021515 40 0.020
epithelial cell fate commitment GO:0072148 11 0.020
Zebrafish
single organism transport GO:0044765 206 0.020
response to glucose GO:0009749 3 0.019
regulation of cell activation GO:0050865 1 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
regulation of inflammatory response GO:0050727 2 0.019
negative regulation of cell fate specification GO:0009996 11 0.019
rhythmic process GO:0048511 21 0.019
positive regulation of cell activation GO:0050867 1 0.019
single organism localization GO:1902578 225 0.019
gtp metabolic process GO:0046039 4 0.019
regulation of cardiac muscle tissue development GO:0055024 1 0.019
positive regulation of synapse assembly GO:0051965 1 0.019
reproductive process GO:0022414 40 0.019
Mouse Rat
regulation of circadian rhythm GO:0042752 4 0.019
negative regulation of kinase activity GO:0033673 4 0.018
steroid hormone mediated signaling pathway GO:0043401 9 0.018
regulation of muscle organ development GO:0048634 9 0.018
embryonic appendage morphogenesis GO:0035113 30 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
programmed cell death GO:0012501 119 0.018
Rat
cell migration GO:0016477 237 0.018
neural crest cell differentiation GO:0014033 72 0.018
chemotaxis GO:0006935 104 0.018
multicellular organism growth GO:0035264 4 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
nucleus localization GO:0051647 8 0.018
digestive tract morphogenesis GO:0048546 231 0.018
purine containing compound metabolic process GO:0072521 29 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
positive regulation of secretion GO:0051047 1 0.017
mesoderm morphogenesis GO:0048332 51 0.017
circadian rhythm GO:0007623 19 0.017
neuron projection morphogenesis GO:0048812 161 0.017
organelle organization GO:0006996 227 0.017
lateral inhibition GO:0046331 1 0.017
endothelial cell differentiation GO:0045446 20 0.017
Zebrafish
multicellular organismal signaling GO:0035637 22 0.017
determination of dorsal ventral asymmetry GO:0048262 34 0.017
primary neural tube formation GO:0014020 1 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
Human Zebrafish Mouse
amine metabolic process GO:0009308 2 0.016
regulation of heart growth GO:0060420 2 0.016
epithelial tube formation GO:0072175 19 0.016
peripheral nervous system development GO:0007422 55 0.016
mesenchymal cell proliferation GO:0010463 1 0.016
organ formation GO:0048645 17 0.016
protein metabolic process GO:0019538 183 0.016
Mouse
regulation of camp metabolic process GO:0030814 9 0.016
tube morphogenesis GO:0035239 349 0.016
myeloid cell homeostasis GO:0002262 56 0.016
muscle cell differentiation GO:0042692 139 0.016
Mouse
alcohol biosynthetic process GO:0046165 2 0.016
small gtpase mediated signal transduction GO:0007264 8 0.016
developmental process involved in reproduction GO:0003006 27 0.016
Mouse Rat
negative regulation of chromosome organization GO:2001251 1 0.016
protein localization GO:0008104 40 0.016
pectoral fin development GO:0033339 50 0.016
negative regulation of nervous system development GO:0051961 22 0.016
neurotransmitter transport GO:0006836 2 0.015
appendage morphogenesis GO:0035107 56 0.015
neuron projection development GO:0031175 180 0.015
Rat
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
Human Zebrafish Mouse Worm
regulation of protein targeting GO:1903533 2 0.015
protein homooligomerization GO:0051260 3 0.015
Human
pronephric duct development GO:0039022 13 0.015
myelination GO:0042552 18 0.015
Rat
forebrain development GO:0030900 96 0.015
multicellular organismal homeostasis GO:0048871 29 0.015
cellular protein catabolic process GO:0044257 4 0.015
tissue homeostasis GO:0001894 25 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
ensheathment of neurons GO:0007272 18 0.015
Rat
posterior lateral line development GO:0048916 38 0.015
endoderm formation GO:0001706 29 0.014
pathway restricted smad protein phosphorylation GO:0060389 1 0.014
bmp signaling pathway involved in heart development GO:0061312 15 0.014
positive regulation of metabolic process GO:0009893 108 0.014
Human Zebrafish Mouse Worm
osteoclast differentiation GO:0030316 1 0.014
skeletal muscle fiber development GO:0048741 35 0.014
negative regulation of cell death GO:0060548 60 0.014
nucleobase containing small molecule metabolic process GO:0055086 32 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
regulation of cell shape GO:0008360 1 0.014
peptidyl threonine phosphorylation GO:0018107 1 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
regulation of membrane potential GO:0042391 23 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
regulation of neuron projection development GO:0010975 40 0.014
developmental programmed cell death GO:0010623 4 0.014
response to corticosteroid GO:0031960 1 0.014
Rat
regulation of cell development GO:0060284 100 0.014
nucleoside phosphate metabolic process GO:0006753 28 0.014

rxraa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
disease of metabolism DOID:0014667 0 0.027
musculoskeletal system disease DOID:17 0 0.021
inherited metabolic disorder DOID:655 0 0.021
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014