Danio rerio

0 known processes

safb

scaffold attachment factor B

(Aliases: zgc:55387,wu:fb40a03,wu:fd42g06)

safb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mrna processing GO:0050684 3 0.914
Fly
regulation of mrna splicing via spliceosome GO:0048024 3 0.911
Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.885
Fly
mrna splicing via spliceosome GO:0000398 10 0.882
Fly
rna splicing GO:0008380 16 0.843
Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.841
Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.623
Fly
regulation of rna splicing GO:0043484 8 0.549
Fly
hemopoiesis GO:0030097 183 0.474
regulation of primary metabolic process GO:0080090 311 0.452
Mouse Fly
mrna processing GO:0006397 14 0.426
Fly
gene expression GO:0010467 252 0.416
Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.401
Mouse Fly
larval development GO:0002164 2 0.287
regulation of metabolic process GO:0019222 359 0.283
Mouse Fly
rna processing GO:0006396 25 0.281
Fly
regulation of gene expression GO:0010468 265 0.234
Mouse Fly
immune system development GO:0002520 191 0.211
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.211
maintenance of location GO:0051235 4 0.194
organic cyclic compound metabolic process GO:1901360 301 0.188
Mouse Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.180
negative regulation of rna splicing GO:0033119 1 0.180
embryo development ending in birth or egg hatching GO:0009792 271 0.178
modification dependent macromolecule catabolic process GO:0043632 3 0.152
cellular nitrogen compound metabolic process GO:0034641 290 0.141
Mouse Fly
locomotion GO:0040011 313 0.139
regulation of macromolecule metabolic process GO:0060255 317 0.133
Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.130
Mouse Fly
mrna metabolic process GO:0016071 20 0.127
Fly
heterocycle metabolic process GO:0046483 290 0.121
Mouse Fly
regulation of signaling GO:0023051 235 0.121
rna localization GO:0006403 4 0.121
modification dependent protein catabolic process GO:0019941 3 0.121
aging GO:0007568 2 0.115
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.114
ubiquitin dependent protein catabolic process GO:0006511 3 0.097
single organism localization GO:1902578 225 0.095
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.095
single organism organelle organization GO:1902589 199 0.094
cytokinesis GO:0000910 3 0.092
regulation of cellular metabolic process GO:0031323 320 0.092
Mouse Fly
rna splicing via transesterification reactions GO:0000375 10 0.092
Fly
regulation of rna metabolic process GO:0051252 224 0.090
Mouse Fly
negative regulation of metabolic process GO:0009892 86 0.088
meiotic nuclear division GO:0007126 4 0.088
regulation of erk1 and erk2 cascade GO:0070372 4 0.086
cellular protein catabolic process GO:0044257 4 0.085
myeloid cell differentiation GO:0030099 86 0.081
positive regulation of leukocyte differentiation GO:1902107 1 0.081
negative regulation of macromolecule metabolic process GO:0010605 76 0.079
heterocycle biosynthetic process GO:0018130 215 0.078
Mouse
immune system process GO:0002376 241 0.078
leukocyte differentiation GO:0002521 25 0.077
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.076
Mouse Fly
positive regulation of ras protein signal transduction GO:0046579 1 0.075
nucleic acid metabolic process GO:0090304 244 0.075
Mouse Fly
cellular component biogenesis GO:0044085 178 0.075
regulation of multicellular organismal development GO:2000026 223 0.072
regulation of nitrogen compound metabolic process GO:0051171 251 0.072
Mouse Fly
nuclear import GO:0051170 3 0.072
programmed cell death GO:0012501 119 0.072
regulation of biological quality GO:0065008 263 0.070
Mouse
rna metabolic process GO:0016070 219 0.068
Mouse Fly
mitotic cell cycle GO:0000278 64 0.068
biosynthetic process GO:0009058 294 0.068
Mouse
nuclear transport GO:0051169 4 0.065
stem cell proliferation GO:0072089 4 0.064
nuclear division GO:0000280 23 0.062
transport GO:0006810 220 0.062
negative regulation of biological process GO:0048519 304 0.062
organelle organization GO:0006996 227 0.061
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.060
locomotor rhythm GO:0045475 3 0.060
organic cyclic compound biosynthetic process GO:1901362 223 0.058
Mouse
nucleocytoplasmic transport GO:0006913 4 0.058
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.056
cellular aromatic compound metabolic process GO:0006725 295 0.056
Mouse Fly
regulation of cytoplasmic transport GO:1903649 4 0.056
mitotic dna integrity checkpoint GO:0044774 4 0.056
regulation of mrna metabolic process GO:1903311 6 0.055
Fly
positive regulation of cellular process GO:0048522 201 0.055
Mouse
regulation of immune system process GO:0002682 34 0.055
regulation of synapse organization GO:0050807 3 0.054
single organism transport GO:0044765 206 0.052
positive regulation of developmental process GO:0051094 50 0.051
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.050
regulation of multicellular organism growth GO:0040014 4 0.049
lipid storage GO:0019915 1 0.049
regulation of protein catabolic process GO:0042176 1 0.048
intracellular signal transduction GO:0035556 85 0.048
positive regulation of metabolic process GO:0009893 108 0.048
Mouse
cytoskeleton organization GO:0007010 96 0.048
regulation of developmental process GO:0050793 247 0.047
negative regulation of gene expression GO:0010629 65 0.047
monocyte differentiation GO:0030224 2 0.045
regulation of signal transduction GO:0009966 225 0.045
proteasomal protein catabolic process GO:0010498 2 0.045
apoptotic process GO:0006915 116 0.044
spliceosomal complex assembly GO:0000245 1 0.044
nucleobase containing compound metabolic process GO:0006139 274 0.044
Mouse Fly
establishment of protein localization to organelle GO:0072594 4 0.044
neuroblast proliferation GO:0007405 2 0.043
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.042
regulation of transcription dna templated GO:0006355 213 0.042
Mouse
meiotic chromosome segregation GO:0045132 3 0.041
single organism metabolic process GO:0044710 217 0.041
amine metabolic process GO:0009308 2 0.041
germ cell development GO:0007281 22 0.041
gamete generation GO:0007276 33 0.040
regulation of cell differentiation GO:0045595 142 0.040
establishment of localization GO:0051234 244 0.040
negative regulation of cellular process GO:0048523 283 0.039
regulation of nucleocytoplasmic transport GO:0046822 2 0.039
regulation of cell death GO:0010941 103 0.039
spermatid differentiation GO:0048515 2 0.039
dna metabolic process GO:0006259 27 0.038
protein metabolic process GO:0019538 183 0.038
development of primary female sexual characteristics GO:0046545 4 0.038
regulation of protein metabolic process GO:0051246 56 0.036
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.036
protein targeting to nucleus GO:0044744 3 0.036
negative regulation of nuclear division GO:0051784 3 0.035
positive regulation of muscle cell differentiation GO:0051149 1 0.034
erythrocyte homeostasis GO:0034101 55 0.034
positive regulation of cell differentiation GO:0045597 30 0.034
ras protein signal transduction GO:0007265 7 0.033
female gonad development GO:0008585 4 0.033
embryonic cranial skeleton morphogenesis GO:0048701 90 0.033
positive regulation of dna templated transcription elongation GO:0032786 1 0.033
regulation of cellular component organization GO:0051128 86 0.033
growth GO:0040007 174 0.033
Mouse
cellular component disassembly GO:0022411 1 0.033
single organism nuclear import GO:1902593 3 0.032
regulation of chromosome segregation GO:0051983 1 0.031
multicellular organism growth GO:0035264 4 0.031
regulation of synapse assembly GO:0051963 3 0.031
regulation of multicellular organismal process GO:0051239 277 0.031
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.031
positive regulation of cellular component biogenesis GO:0044089 3 0.031
nuclear migration GO:0007097 3 0.030
positive regulation of myeloid cell differentiation GO:0045639 2 0.029
regulation of cell cycle GO:0051726 52 0.029
cell death GO:0008219 121 0.029
cellular amine metabolic process GO:0044106 2 0.028
negative regulation of mitosis GO:0045839 3 0.028
response to stress GO:0006950 263 0.028
myeloid cell homeostasis GO:0002262 56 0.028
small gtpase mediated signal transduction GO:0007264 8 0.028
rna export from nucleus GO:0006405 1 0.028
regulation of cell communication GO:0010646 232 0.027
rna transport GO:0050658 2 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
single organism reproductive process GO:0044702 40 0.027
regulation of cellular protein catabolic process GO:1903362 1 0.027
female sex differentiation GO:0046660 4 0.026
protein import into nucleus GO:0006606 3 0.026
positive regulation of mrna metabolic process GO:1903313 2 0.026
protein import GO:0017038 3 0.026
negative regulation of mrna metabolic process GO:1903312 3 0.025
nuclear export GO:0051168 1 0.025
posttranscriptional regulation of gene expression GO:0010608 14 0.025
signal transduction GO:0007165 455 0.025
Mouse
multi organism reproductive process GO:0044703 36 0.025
positive regulation of gene expression GO:0010628 71 0.025
Mouse
protein localization to nucleus GO:0034504 3 0.025
response to chemical GO:0042221 320 0.024
reproductive process GO:0022414 40 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
Mouse
positive regulation of biological process GO:0048518 253 0.024
Mouse
phagocytosis GO:0006909 3 0.024
cellular localization GO:0051641 97 0.024
pronuclear migration GO:0035046 1 0.024
negative regulation of cellular metabolic process GO:0031324 77 0.023
stem cell division GO:0017145 1 0.023
translational initiation GO:0006413 3 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
aromatic compound biosynthetic process GO:0019438 217 0.023
Mouse
regulation of establishment of protein localization GO:0070201 4 0.023
regulation of cell activation GO:0050865 1 0.023
phosphate containing compound metabolic process GO:0006796 108 0.023
organic acid metabolic process GO:0006082 31 0.022
regulation of organelle organization GO:0033043 29 0.022
developmental process involved in reproduction GO:0003006 27 0.022
phosphorylation GO:0016310 69 0.022
organism emergence from protective structure GO:0071684 4 0.022
cellular ketone metabolic process GO:0042180 11 0.022
positive regulation of cell cycle GO:0045787 3 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
neuron development GO:0048666 262 0.022
microtubule based process GO:0007017 60 0.021
mitotic nuclear division GO:0007067 18 0.021
regulation of cellular protein metabolic process GO:0032268 52 0.021
protein polymerization GO:0051258 4 0.021
cellular protein metabolic process GO:0044267 129 0.021
organelle fission GO:0048285 23 0.021
mitotic dna damage checkpoint GO:0044773 4 0.021
gene silencing by rna GO:0031047 4 0.021
positive regulation of cell activation GO:0050867 1 0.021
regulation of response to stimulus GO:0048583 269 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
mesenchyme development GO:0060485 127 0.020
multicellular organismal reproductive process GO:0048609 35 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
nucleobase containing compound transport GO:0015931 2 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
Mouse
positive regulation of rna splicing GO:0033120 1 0.019
response to organic substance GO:0010033 153 0.019
macromolecular complex disassembly GO:0032984 1 0.019
response to uv GO:0009411 3 0.019
neural crest cell differentiation GO:0014033 72 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
positive regulation of dna metabolic process GO:0051054 1 0.019
regulation of protein complex disassembly GO:0043244 1 0.019
mesenchymal cell differentiation GO:0048762 87 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
regulation of circadian rhythm GO:0042752 4 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
response to external stimulus GO:0009605 264 0.018
centrosome organization GO:0051297 1 0.018
signal transduction by phosphorylation GO:0023014 18 0.018
negative regulation of synapse assembly GO:0051964 2 0.018
cellular response to stress GO:0033554 62 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
regionalization GO:0003002 274 0.018
negative regulation of dna metabolic process GO:0051053 4 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
positive regulation of multicellular organismal process GO:0051240 52 0.018
rna biosynthetic process GO:0032774 181 0.017
Mouse
regulation of gene expression epigenetic GO:0040029 11 0.017
macromolecule localization GO:0033036 54 0.017
response to abiotic stimulus GO:0009628 122 0.017
regulation of protein transport GO:0051223 3 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
interspecies interaction between organisms GO:0044419 4 0.017
response to drug GO:0042493 3 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
Mouse
g2 dna damage checkpoint GO:0031572 3 0.017
regulation of protein targeting GO:1903533 2 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.016
cell projection organization GO:0030030 284 0.016
erythrocyte differentiation GO:0030218 54 0.016
g2 m transition of mitotic cell cycle GO:0000086 4 0.016
fertilization GO:0009566 3 0.016
regulation of mitosis GO:0007088 9 0.016
peptidyl threonine phosphorylation GO:0018107 1 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
regulation of translational initiation GO:0006446 1 0.016
death GO:0016265 121 0.016
embryonic organ development GO:0048568 381 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
cellular biosynthetic process GO:0044249 286 0.016
Mouse
entrainment of circadian clock by photoperiod GO:0043153 1 0.016
epithelial cell differentiation GO:0030855 116 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
Mouse
negative regulation of developmental process GO:0051093 65 0.015
regulation of programmed cell death GO:0043067 101 0.015
spermatid development GO:0007286 2 0.015
meiotic cell cycle process GO:1903046 3 0.015
cellular component assembly GO:0022607 170 0.015
regulation of dna templated transcription elongation GO:0032784 3 0.015
ribonucleoprotein complex biogenesis GO:0022613 13 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
neuromuscular synaptic transmission GO:0007274 2 0.015
dna catabolic process GO:0006308 1 0.015
microtubule cytoskeleton organization GO:0000226 33 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
positive regulation of mrna splicing via spliceosome GO:0048026 1 0.015
protein complex disassembly GO:0043241 1 0.015
dna templated transcription elongation GO:0006354 3 0.014
homeostasis of number of cells GO:0048872 62 0.014
cellular macromolecule catabolic process GO:0044265 12 0.014
cell cycle GO:0007049 93 0.014
regulation of cell shape GO:0008360 1 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
cytoplasm organization GO:0007028 4 0.014
positive regulation of synapse assembly GO:0051965 1 0.014
viral process GO:0016032 1 0.014
hatching GO:0035188 4 0.014
oxoacid metabolic process GO:0043436 31 0.014
protein k63 linked ubiquitination GO:0070534 2 0.014
cell cycle process GO:0022402 53 0.014
macromolecular complex assembly GO:0065003 35 0.014
primary neural tube formation GO:0014020 1 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
regulation of apoptotic process GO:0042981 98 0.013
cell morphogenesis GO:0000902 289 0.013
phosphorus metabolic process GO:0006793 109 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
chemosensory behavior GO:0007635 1 0.013
mechanosensory behavior GO:0007638 2 0.013
sexual reproduction GO:0019953 36 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
intracellular transport GO:0046907 32 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
negative regulation of dna replication GO:0008156 2 0.013
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.013
multicellular organism reproduction GO:0032504 35 0.013
protein complex subunit organization GO:0071822 46 0.013
mitotic cell cycle process GO:1903047 48 0.013
multi organism cellular process GO:0044764 2 0.012
mitotic metaphase plate congression GO:0007080 1 0.012
nucleic acid transport GO:0050657 2 0.012
pole plasm assembly GO:0007315 4 0.012
intracellular estrogen receptor signaling pathway GO:0030520 3 0.012
Mouse
stem cell maintenance GO:0019827 4 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
reproduction GO:0000003 40 0.012
blood vessel morphogenesis GO:0048514 216 0.012
sister chromatid segregation GO:0000819 6 0.012
developmental growth GO:0048589 166 0.012
regulation of locomotion GO:0040012 55 0.012
neuron differentiation GO:0030182 353 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
posttranscriptional gene silencing GO:0016441 3 0.012
positive regulation of myeloid leukocyte differentiation GO:0002763 1 0.012
cell motility GO:0048870 244 0.012
double strand break repair GO:0006302 3 0.012
regulation of dna replication GO:0006275 3 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
Mouse
centrosome cycle GO:0007098 1 0.011
cellular response to dsrna GO:0071359 1 0.011
microtubule polymerization GO:0046785 2 0.011
positive regulation of cell communication GO:0010647 56 0.011
histone h3 k4 methylation GO:0051568 2 0.011
regulation of chromosome organization GO:0033044 5 0.011
proteolysis GO:0006508 38 0.011
mrna transport GO:0051028 2 0.011
negative regulation of multi organism process GO:0043901 3 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
Mouse
mitotic g2 m transition checkpoint GO:0044818 3 0.011
negative regulation of cell death GO:0060548 60 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
organic substance biosynthetic process GO:1901576 289 0.011
Mouse
meiotic spindle organization GO:0000212 1 0.011
cell cycle g2 m phase transition GO:0044839 4 0.011
negative regulation of protein metabolic process GO:0051248 16 0.011
dsrna fragmentation GO:0031050 1 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
axonogenesis GO:0007409 152 0.011
regulation of phosphorus metabolic process GO:0051174 43 0.011
hematopoietic progenitor cell differentiation GO:0002244 23 0.011
regulation of cell division GO:0051302 12 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
chromosome organization involved in meiosis GO:0070192 1 0.010
nephron epithelium morphogenesis GO:0072088 1 0.010
homeostatic process GO:0042592 142 0.010
determination of bilateral symmetry GO:0009855 204 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
positive regulation of catabolic process GO:0009896 4 0.010
negative regulation of cell cycle GO:0045786 14 0.010
establishment of rna localization GO:0051236 3 0.010
negative regulation of catabolic process GO:0009895 3 0.010
nephron tubule morphogenesis GO:0072078 1 0.010
regulation of myeloid leukocyte differentiation GO:0002761 5 0.010
forebrain development GO:0030900 96 0.010
cellular component morphogenesis GO:0032989 336 0.010
cellular response to starvation GO:0009267 1 0.010

safb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
motor neuron disease DOID:231 0 0.555
central nervous system disease DOID:331 0 0.555
amyotrophic lateral sclerosis DOID:332 0 0.555
disease of anatomical entity DOID:7 0 0.555
neurodegenerative disease DOID:1289 0 0.555
nervous system disease DOID:863 0 0.555
musculoskeletal system disease DOID:17 0 0.029
myopathy DOID:423 0 0.018
muscular disease DOID:0080000 0 0.018
muscle tissue disease DOID:66 0 0.018