Danio rerio

0 known processes

sb:cb81

sb:cb81

(Aliases: cb81)

sb:cb81 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
mediolateral intercalation GO:0060031 3 0.874
morphogenesis of an epithelium GO:0002009 333 0.749
response to external stimulus GO:0009605 264 0.279
cytoskeleton dependent cytokinesis GO:0061640 3 0.249
negative regulation of cellular process GO:0048523 283 0.242
regulation of multicellular organismal development GO:2000026 223 0.239
negative regulation of biological process GO:0048519 304 0.230
central nervous system development GO:0007417 387 0.198
brain development GO:0007420 293 0.182
maintenance of location GO:0051235 4 0.170
generation of neurons GO:0048699 385 0.169
tube morphogenesis GO:0035239 349 0.168
adult behavior GO:0030534 2 0.167
cell morphogenesis GO:0000902 289 0.161
regulation of biological quality GO:0065008 263 0.151
regulation of neuron differentiation GO:0045664 56 0.146
cellular protein catabolic process GO:0044257 4 0.135
gastrulation GO:0007369 208 0.134
regulation of embryonic development GO:0045995 47 0.134
regulation of cell communication GO:0010646 232 0.133
epithelial cell morphogenesis GO:0003382 2 0.130
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.126
cell morphogenesis involved in differentiation GO:0000904 195 0.123
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.121
negative regulation of stem cell differentiation GO:2000737 2 0.118
organonitrogen compound metabolic process GO:1901564 74 0.113
axon development GO:0061564 166 0.113
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.109
sequestering of metal ion GO:0051238 3 0.105
epithelial cilium movement GO:0003351 15 0.105
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.104
non canonical wnt signaling pathway GO:0035567 13 0.098
convergent extension GO:0060026 118 0.098
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.097
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.096
dorsal ventral pattern formation GO:0009953 125 0.095
negative regulation of multicellular organismal process GO:0051241 69 0.094
otolith formation GO:0032475 2 0.091
modification dependent protein catabolic process GO:0019941 3 0.091
otic vesicle development GO:0071599 42 0.088
epithelial cell morphogenesis involved in gastrulation GO:0003381 1 0.086
blood vessel morphogenesis GO:0048514 216 0.085
regulation of metabolic process GO:0019222 359 0.085
neuron differentiation GO:0030182 353 0.084
axonogenesis GO:0007409 152 0.083
amine metabolic process GO:0009308 2 0.082
regulation of stem cell differentiation GO:2000736 4 0.081
intracellular receptor signaling pathway GO:0030522 30 0.080
regulation of anatomical structure morphogenesis GO:0022603 130 0.079
regulation of canonical wnt signaling pathway GO:0060828 34 0.075
morphogenesis of embryonic epithelium GO:0016331 30 0.073
primary neural tube formation GO:0014020 1 0.073
cell part morphogenesis GO:0032990 246 0.071
regionalization GO:0003002 274 0.070
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.068
organelle organization GO:0006996 227 0.067
neuron projection morphogenesis GO:0048812 161 0.066
spinal cord anterior posterior patterning GO:0021512 1 0.066
cellular component morphogenesis GO:0032989 336 0.065
cellular amine metabolic process GO:0044106 2 0.065
enzyme linked receptor protein signaling pathway GO:0007167 106 0.064
negative regulation of nuclear division GO:0051784 3 0.064
regulation of collateral sprouting GO:0048670 7 0.062
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.062
multi organism process GO:0051704 134 0.060
single organism localization GO:1902578 225 0.059
cellular nitrogen compound metabolic process GO:0034641 290 0.058
negative regulation of neuron projection regeneration GO:0070571 4 0.058
establishment of mitotic spindle orientation GO:0000132 10 0.058
otic vesicle morphogenesis GO:0071600 34 0.058
mesodermal cell differentiation GO:0048333 21 0.054
forebrain development GO:0030900 96 0.053
positive regulation of biological process GO:0048518 253 0.053
regulation of cell morphogenesis GO:0022604 42 0.053
regulation of cellular metabolic process GO:0031323 320 0.052
hindbrain development GO:0030902 91 0.052
regulation of protein transport GO:0051223 3 0.051
regulation of establishment of protein localization GO:0070201 4 0.049
cell projection morphogenesis GO:0048858 244 0.049
anterior head development GO:0097065 2 0.049
embryo development ending in birth or egg hatching GO:0009792 271 0.048
neuron development GO:0048666 262 0.048
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.048
positive regulation of cellular component biogenesis GO:0044089 3 0.048
negative regulation of response to stimulus GO:0048585 104 0.047
regulation of wnt signaling pathway GO:0030111 53 0.047
cytoskeleton organization GO:0007010 96 0.047
protein import into nucleus GO:0006606 3 0.047
aging GO:0007568 2 0.047
ventricular system development GO:0021591 12 0.047
regulation of catenin import into nucleus GO:0035412 2 0.046
stem cell maintenance GO:0019827 4 0.046
negative regulation of sequestering of calcium ion GO:0051283 4 0.046
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.046
digestive system development GO:0055123 289 0.046
negative chemotaxis GO:0050919 1 0.045
cation homeostasis GO:0055080 33 0.045
rhombomere development GO:0021546 19 0.045
regulation of mesoderm development GO:2000380 11 0.044
tube formation GO:0035148 25 0.044
regulation of ectodermal cell fate specification GO:0042665 2 0.044
release of sequestered calcium ion into cytosol GO:0051209 3 0.043
blood vessel development GO:0001568 246 0.043
ion homeostasis GO:0050801 41 0.042
regulation of growth GO:0040008 42 0.042
regulation of establishment of planar polarity GO:0090175 4 0.041
hepatic duct development GO:0061011 2 0.041
wnt signaling pathway GO:0016055 80 0.041
convergent extension involved in gastrulation GO:0060027 71 0.040
regulation of developmental process GO:0050793 247 0.040
immune system process GO:0002376 241 0.039
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.039
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.039
regulation of cytoskeleton organization GO:0051493 11 0.038
determination of bilateral symmetry GO:0009855 204 0.038
locomotion GO:0040011 313 0.038
somite development GO:0061053 96 0.037
actin filament bundle organization GO:0061572 6 0.037
mitotic cell cycle GO:0000278 64 0.037
regulation of microtubule cytoskeleton organization GO:0070507 3 0.037
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.036
regulation of non canonical wnt signaling pathway GO:2000050 7 0.036
inner ear development GO:0048839 126 0.036
regulation of nucleocytoplasmic transport GO:0046822 2 0.036
small gtpase mediated signal transduction GO:0007264 8 0.036
regulation of response to stimulus GO:0048583 269 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.035
small molecule metabolic process GO:0044281 77 0.035
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.035
regulation of cellular amine metabolic process GO:0033238 0 0.035
formation of primary germ layer GO:0001704 62 0.035
skeletal system development GO:0001501 181 0.035
negative regulation of mitosis GO:0045839 3 0.035
ear morphogenesis GO:0042471 64 0.035
regulation of multicellular organismal process GO:0051239 277 0.034
keratinocyte differentiation GO:0030216 0 0.034
developmental growth involved in morphogenesis GO:0060560 86 0.034
ectodermal placode morphogenesis GO:0071697 32 0.033
sensory organ development GO:0007423 393 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
monoamine transport GO:0015844 1 0.033
negative regulation of protein transport GO:0051224 3 0.033
nucleic acid metabolic process GO:0090304 244 0.032
positive regulation of transport GO:0051050 2 0.032
regulation of collateral sprouting in absence of injury GO:0048696 4 0.032
regulation of cellular ketone metabolic process GO:0010565 7 0.032
developmental growth GO:0048589 166 0.032
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.032
epiboly GO:0090504 41 0.032
regulation of anterior head development GO:2000742 2 0.031
gamete generation GO:0007276 33 0.031
protein localization to nucleus GO:0034504 3 0.031
cell migration GO:0016477 237 0.031
neuron projection development GO:0031175 180 0.031
heterocycle metabolic process GO:0046483 290 0.031
regulation of protein catabolic process GO:0042176 1 0.031
actin filament based movement GO:0030048 1 0.030
growth GO:0040007 174 0.030
lipid storage GO:0019915 1 0.030
cellular localization GO:0051641 97 0.030
cell fate commitment GO:0045165 99 0.030
germ line stem cell maintenance GO:0030718 2 0.030
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.030
regulation of hormone secretion GO:0046883 2 0.030
negative regulation of collateral sprouting GO:0048671 2 0.029
macromolecule localization GO:0033036 54 0.029
cellular ion homeostasis GO:0006873 17 0.029
aorta development GO:0035904 4 0.029
larval development GO:0002164 2 0.029
habenula development GO:0021986 9 0.029
hindbrain morphogenesis GO:0021575 22 0.029
regulation of peptidase activity GO:0052547 23 0.029
multicellular organism reproduction GO:0032504 35 0.028
ectodermal placode formation GO:0060788 26 0.028
synaptic growth at neuromuscular junction GO:0051124 2 0.028
regulation of molecular function GO:0065009 70 0.028
circadian sleep wake cycle sleep GO:0050802 1 0.028
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.028
regulation of cell projection organization GO:0031344 44 0.027
regulation of signaling GO:0023051 235 0.027
regulation of cell shape GO:0008360 1 0.027
unidimensional cell growth GO:0009826 5 0.027
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.027
fourth ventricle development GO:0021592 8 0.027
head development GO:0060322 303 0.027
calcium ion transport into cytosol GO:0060402 3 0.027
regulation of catalytic activity GO:0050790 55 0.026
rna metabolic process GO:0016070 219 0.026
regulation of protein metabolic process GO:0051246 56 0.026
stem cell division GO:0017145 1 0.026
multicellular organism growth GO:0035264 4 0.026
macromolecular complex subunit organization GO:0043933 74 0.025
embryonic organ morphogenesis GO:0048562 274 0.025
tube closure GO:0060606 1 0.025
regulation of cell death GO:0010941 103 0.025
gall bladder development GO:0061010 1 0.025
regulation of cytoplasmic transport GO:1903649 4 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
hepatocyte proliferation GO:0072574 2 0.024
facial nerve development GO:0021561 3 0.024
protein targeting to nucleus GO:0044744 3 0.024
ear development GO:0043583 127 0.024
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.024
signal transduction GO:0007165 455 0.024
cellular cation homeostasis GO:0030003 17 0.024
ion transport GO:0006811 114 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
response to fibroblast growth factor GO:0071774 22 0.023
skin development GO:0043588 54 0.023
regulation of sequestering of calcium ion GO:0051282 4 0.023
regulation of nervous system development GO:0051960 90 0.023
cell projection organization GO:0030030 284 0.023
positive regulation of cell cycle GO:0045787 3 0.023
negative regulation of wnt signaling pathway GO:0030178 30 0.023
regulation of cellular component size GO:0032535 30 0.022
single organism nuclear import GO:1902593 3 0.022
cellular macromolecule metabolic process GO:0044260 391 0.022
negative regulation of signaling GO:0023057 96 0.021
chordate embryonic development GO:0043009 271 0.021
rhombomere formation GO:0021594 12 0.021
oocyte differentiation GO:0009994 14 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.021
regulation of gastrulation GO:0010470 24 0.021
digestive tract morphogenesis GO:0048546 231 0.021
germ cell development GO:0007281 22 0.021
cellular ketone metabolic process GO:0042180 11 0.021
homeostatic process GO:0042592 142 0.021
morphogenesis of an epithelial sheet GO:0002011 49 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
embryonic limb morphogenesis GO:0030326 2 0.021
positive regulation of protein complex assembly GO:0031334 2 0.021
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.020
tissue regeneration GO:0042246 74 0.020
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.020
negative regulation of secretion by cell GO:1903531 2 0.020
developmental cell growth GO:0048588 52 0.020
single organism organelle organization GO:1902589 199 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
oxoacid metabolic process GO:0043436 31 0.019
regulation of phosphate metabolic process GO:0019220 43 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
cell migration in hindbrain GO:0021535 7 0.019
optic placode formation GO:0001743 4 0.019
regulation of cell activation GO:0050865 1 0.019
protein complex subunit organization GO:0071822 46 0.019
neural tube development GO:0021915 62 0.019
regulation of glial cell differentiation GO:0045685 4 0.019
regulation of ph GO:0006885 3 0.019
protein metabolic process GO:0019538 183 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
hormone transport GO:0009914 2 0.019
sleep GO:0030431 1 0.018
common bile duct development GO:0061009 13 0.018
cortical actin cytoskeleton organization GO:0030866 1 0.018
collateral sprouting of intact axon in response to injury GO:0048673 2 0.018
nuclear transport GO:0051169 4 0.018
anterior posterior pattern specification GO:0009952 152 0.018
post anal tail morphogenesis GO:0036342 19 0.018
negative regulation of transcription dna templated GO:0045892 45 0.018
growth plate cartilage development GO:0003417 2 0.018
cell fate specification GO:0001708 68 0.018
establishment of organelle localization GO:0051656 45 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
canonical wnt signaling pathway GO:0060070 48 0.018
negative regulation of gliogenesis GO:0014014 1 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
neural keel formation GO:0014025 1 0.018
organic acid metabolic process GO:0006082 31 0.017
regulation of tube size GO:0035150 2 0.017
otic vesicle formation GO:0030916 27 0.017
cytosolic calcium ion transport GO:0060401 3 0.017
establishment of localization in cell GO:0051649 77 0.017
axis specification GO:0009798 43 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
regulation of axonogenesis GO:0050770 32 0.017
carbohydrate homeostasis GO:0033500 1 0.017
chemical homeostasis GO:0048878 49 0.017
cellular response to growth factor stimulus GO:0071363 39 0.017
rhombomere boundary formation GO:0021654 10 0.017
regulation of epidermis development GO:0045682 2 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
wound healing GO:0042060 90 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
transcription dna templated GO:0006351 181 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
positive regulation of neuron apoptotic process GO:0043525 1 0.017
system process GO:0003008 185 0.017
connective tissue development GO:0061448 99 0.017
otic placode formation GO:0043049 23 0.016
cell death GO:0008219 121 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
cellular response to oxygen levels GO:0071453 1 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
neuromast mantle cell differentiation GO:0048888 1 0.016
axon guidance GO:0007411 86 0.016
cell growth GO:0016049 57 0.016
developmental maturation GO:0021700 34 0.016
ameboidal type cell migration GO:0001667 143 0.016
regulation of gene expression GO:0010468 265 0.016
determination of pancreatic left right asymmetry GO:0035469 11 0.016
mesodermal cell fate commitment GO:0001710 14 0.016
negative regulation of developmental process GO:0051093 65 0.016
response to stress GO:0006950 263 0.016
nuclear import GO:0051170 3 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.016
ectodermal placode development GO:0071696 37 0.016
regulation of phosphorus metabolic process GO:0051174 43 0.015
actin filament based process GO:0030029 64 0.015
dna modification GO:0006304 8 0.015
regulation of intracellular signal transduction GO:1902531 57 0.015
synaptic target recognition GO:0008039 1 0.015
thrombocyte differentiation GO:0002574 4 0.015
regulation of rna metabolic process GO:0051252 224 0.015
organelle localization GO:0051640 49 0.015
vasculature development GO:0001944 278 0.015
biosynthetic process GO:0009058 294 0.015
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.015
regulation of intracellular ph GO:0051453 1 0.015
mesoderm development GO:0007498 88 0.015
regulation of localization GO:0032879 104 0.015
liver development GO:0001889 96 0.015
cilium organization GO:0044782 71 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
hormone secretion GO:0046879 2 0.014
ras protein signal transduction GO:0007265 7 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
angiogenesis GO:0001525 158 0.014
determination of left right symmetry GO:0007368 179 0.014
negative regulation of signal transduction GO:0009968 94 0.014
death GO:0016265 121 0.014
inner ear morphogenesis GO:0042472 63 0.014
proteolysis GO:0006508 38 0.014
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.014
specification of axis polarity GO:0065001 4 0.014
rhombomere 4 development GO:0021570 5 0.014
negative regulation of cellular component organization GO:0051129 16 0.014
divalent inorganic cation transport GO:0072511 21 0.014
ectoderm development GO:0007398 9 0.014
proximal distal pattern formation GO:0009954 1 0.014
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.014
endochondral bone growth GO:0003416 2 0.014
type b pancreatic cell proliferation GO:0044342 1 0.014
protein secretion GO:0009306 1 0.013
cell migration involved in gastrulation GO:0042074 79 0.013
protein import GO:0017038 3 0.013
regulation of signal transduction GO:0009966 225 0.013
mammillary body development GO:0021767 4 0.013
embryonic epithelial tube formation GO:0001838 17 0.013
neuromuscular process controlling balance GO:0050885 3 0.013
regulation of protein modification process GO:0031399 29 0.013
regulation of transport GO:0051049 45 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 1 0.013
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.013
b cell activation GO:0042113 2 0.013
response to lipid GO:0033993 60 0.013
neural crest formation GO:0014029 14 0.013
regeneration GO:0031099 91 0.013
urogenital system development GO:0001655 97 0.012
neurological system process GO:0050877 62 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of cell fate commitment GO:0010453 22 0.012
multicellular organismal signaling GO:0035637 22 0.012
negative regulation of developmental growth GO:0048640 9 0.012
ion transmembrane transport GO:0034220 91 0.012
otolith development GO:0048840 32 0.012
negative regulation of cell fate specification GO:0009996 11 0.012
phagocytosis GO:0006909 3 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
regulation of anatomical structure size GO:0090066 33 0.012
negative regulation of cell communication GO:0010648 96 0.012
regulation of locomotion GO:0040012 55 0.012
single organism transport GO:0044765 206 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
actin filament bundle assembly GO:0051017 6 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
negative regulation of multi organism process GO:0043901 3 0.011
cell motility GO:0048870 244 0.011
fin development GO:0033333 77 0.011
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.011
retinoic acid receptor signaling pathway GO:0048384 16 0.011
localization of cell GO:0051674 244 0.011
nuclear export GO:0051168 1 0.011
cell maturation GO:0048469 23 0.011
neural tube formation GO:0001841 16 0.011
gastrulation with mouth forming second GO:0001702 44 0.011
transport GO:0006810 220 0.011
ectodermal cell fate specification GO:0001715 2 0.011
startle response GO:0001964 4 0.011
regulation of body fluid levels GO:0050878 16 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
regulation of synapse assembly GO:0051963 3 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
facial nerve morphogenesis GO:0021610 1 0.011
dorsal convergence GO:0060030 14 0.011
response to wounding GO:0009611 116 0.010
regulation of cell size GO:0008361 29 0.010
regulation of actin cytoskeleton organization GO:0032956 8 0.010
multicellular organismal water homeostasis GO:0050891 1 0.010
embryonic organ development GO:0048568 381 0.010
cation transport GO:0006812 81 0.010
gtp catabolic process GO:0006184 2 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
regulation of protein targeting GO:1903533 2 0.010
sensory neuron axon guidance GO:0097374 3 0.010
calcium ion transport GO:0006816 18 0.010
regulation of neuron projection development GO:0010975 40 0.010
regulation of primary metabolic process GO:0080090 311 0.010
sequestering of calcium ion GO:0051208 3 0.010
regulation of blood vessel size GO:0050880 2 0.010
axis elongation GO:0003401 31 0.010
protein polymerization GO:0051258 4 0.010
mitotic cytokinesis GO:0000281 3 0.010
rhombomere morphogenesis GO:0021593 17 0.010

sb:cb81 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.040
disease of cellular proliferation DOID:14566 0 0.040
organ system cancer DOID:0050686 0 0.022