Danio rerio

0 known processes

sb:cb930

sb:cb930

sb:cb930 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
alpha amino acid metabolic process GO:1901605 3 0.151
nuclear transport GO:0051169 4 0.125
organic substance biosynthetic process GO:1901576 289 0.122
organic cyclic compound metabolic process GO:1901360 301 0.103
protein localization to nucleus GO:0034504 3 0.098
cellular biosynthetic process GO:0044249 286 0.093
biosynthetic process GO:0009058 294 0.089
larval development GO:0002164 2 0.083
regulation of biological quality GO:0065008 263 0.082
response to external stimulus GO:0009605 264 0.078
cellular modified amino acid metabolic process GO:0006575 3 0.078
maintenance of location GO:0051235 4 0.075
response to alkaloid GO:0043279 2 0.074
heart development GO:0007507 313 0.073
positive regulation of cell cycle GO:0045787 3 0.071
positive regulation of cellular component biogenesis GO:0044089 3 0.070
regulation of macromolecule metabolic process GO:0060255 317 0.066
regulation of protein complex assembly GO:0043254 3 0.066
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.064
cellular macromolecule metabolic process GO:0044260 391 0.062
nuclear import GO:0051170 3 0.062
organic acid metabolic process GO:0006082 31 0.062
regulation of gene expression GO:0010468 265 0.061
cellular macromolecule biosynthetic process GO:0034645 224 0.061
regulation of neutrophil migration GO:1902622 6 0.060
cellular amino acid metabolic process GO:0006520 7 0.059
aging GO:0007568 2 0.059
single organism metabolic process GO:0044710 217 0.058
organic cyclic compound biosynthetic process GO:1901362 223 0.058
regulation of nitrogen compound metabolic process GO:0051171 251 0.058
regulation of response to stimulus GO:0048583 269 0.056
cell surface receptor signaling pathway GO:0007166 325 0.056
single organism nuclear import GO:1902593 3 0.055
immune system process GO:0002376 241 0.053
regulation of developmental process GO:0050793 247 0.053
cellular response to external stimulus GO:0071496 2 0.052
regulation of circadian rhythm GO:0042752 4 0.052
macromolecule biosynthetic process GO:0009059 227 0.052
cellular response to oxygen levels GO:0071453 1 0.050
oxoacid metabolic process GO:0043436 31 0.049
nitrogen compound metabolic process GO:0006807 319 0.049
nucleobase containing compound metabolic process GO:0006139 274 0.049
response to biotic stimulus GO:0009607 97 0.048
positive regulation of protein complex assembly GO:0031334 2 0.048
positive regulation of cellular catabolic process GO:0031331 3 0.047
protein import into nucleus GO:0006606 3 0.047
amine metabolic process GO:0009308 2 0.046
small molecule metabolic process GO:0044281 77 0.045
morphogenesis of an epithelium GO:0002009 333 0.045
cellular component movement GO:0006928 335 0.044
establishment of protein localization to organelle GO:0072594 4 0.043
stem cell proliferation GO:0072089 4 0.041
nucleocytoplasmic transport GO:0006913 4 0.041
stem cell maintenance GO:0019827 4 0.039
protein import GO:0017038 3 0.039
positive regulation of transport GO:0051050 2 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
cellular nitrogen compound metabolic process GO:0034641 290 0.039
response to stress GO:0006950 263 0.039
regulation of cellular metabolic process GO:0031323 320 0.038
regulation of signal transduction GO:0009966 225 0.038
g protein coupled receptor signaling pathway GO:0007186 74 0.038
protein targeting to nucleus GO:0044744 3 0.038
response to external biotic stimulus GO:0043207 97 0.038
signal transduction GO:0007165 455 0.037
cell morphogenesis involved in differentiation GO:0000904 195 0.037
regulation of anatomical structure morphogenesis GO:0022603 130 0.037
regulation of sodium ion transport GO:0002028 2 0.037
protein dephosphorylation GO:0006470 3 0.037
regulation of cell projection assembly GO:0060491 4 0.037
embryonic organ development GO:0048568 381 0.036
positive regulation of catabolic process GO:0009896 4 0.036
estrogen metabolic process GO:0008210 2 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
heterocycle metabolic process GO:0046483 290 0.036
aromatic compound biosynthetic process GO:0019438 217 0.036
protein complex localization GO:0031503 1 0.036
negative regulation of biological process GO:0048519 304 0.036
enzyme linked receptor protein signaling pathway GO:0007167 106 0.035
transcription dna templated GO:0006351 181 0.035
regulation of metabolic process GO:0019222 359 0.034
response to nutrient GO:0007584 3 0.034
nucleic acid templated transcription GO:0097659 181 0.034
carboxylic acid metabolic process GO:0019752 22 0.034
ameboidal type cell migration GO:0001667 143 0.033
tube morphogenesis GO:0035239 349 0.033
skin development GO:0043588 54 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
response to oxygen levels GO:0070482 25 0.033
cellular response to decreased oxygen levels GO:0036294 1 0.033
androgen metabolic process GO:0008209 2 0.033
defense response GO:0006952 47 0.033
lipid storage GO:0019915 1 0.033
rna biosynthetic process GO:0032774 181 0.032
muscle tissue development GO:0060537 110 0.032
generation of neurons GO:0048699 385 0.031
negative regulation of cellular process GO:0048523 283 0.031
axon ensheathment in central nervous system GO:0032291 2 0.031
gene expression GO:0010467 252 0.031
response to decreased oxygen levels GO:0036293 25 0.031
skeletal muscle organ development GO:0060538 78 0.031
cellular hormone metabolic process GO:0034754 19 0.031
apoptotic process GO:0006915 116 0.030
regulation of purine nucleotide catabolic process GO:0033121 2 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.030
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.030
lateral inhibition GO:0046331 1 0.030
cellular response to hypoxia GO:0071456 1 0.030
regulation of cytokine production GO:0001817 3 0.030
striated muscle tissue development GO:0014706 110 0.030
digestive system development GO:0055123 289 0.029
digestive tract development GO:0048565 265 0.029
regulation of stem cell differentiation GO:2000736 4 0.029
regulation of filopodium assembly GO:0051489 2 0.029
cellular amine metabolic process GO:0044106 2 0.029
negative regulation of metabolic process GO:0009892 86 0.028
cell motility GO:0048870 244 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.028
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.028
determination of bilateral symmetry GO:0009855 204 0.028
sensory organ development GO:0007423 393 0.028
brain development GO:0007420 293 0.027
localization of cell GO:0051674 244 0.027
protein modification process GO:0036211 100 0.027
positive regulation of cytoskeleton organization GO:0051495 3 0.027
vasculature development GO:0001944 278 0.027
response to chemical GO:0042221 320 0.027
cellular response to chemical stimulus GO:0070887 157 0.027
heterocycle biosynthetic process GO:0018130 215 0.026
inner ear development GO:0048839 126 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
anion transport GO:0006820 38 0.026
negative regulation of epithelial cell proliferation GO:0050680 1 0.026
positive regulation of protein polymerization GO:0032273 2 0.026
negative regulation of kinase activity GO:0033673 4 0.025
regulation of cell shape GO:0008360 1 0.025
fat soluble vitamin metabolic process GO:0006775 4 0.025
regulation of biosynthetic process GO:0009889 250 0.025
central nervous system myelination GO:0022010 2 0.025
rna metabolic process GO:0016070 219 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.025
positive regulation of biosynthetic process GO:0009891 68 0.025
gtp catabolic process GO:0006184 2 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
regulation of locomotion GO:0040012 55 0.025
head development GO:0060322 303 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.024
central nervous system development GO:0007417 387 0.024
protein metabolic process GO:0019538 183 0.023
sleep GO:0030431 1 0.023
response to organic substance GO:0010033 153 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
negative regulation of macromolecule metabolic process GO:0010605 76 0.023
regulation of rna biosynthetic process GO:2001141 213 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.022
cellular protein modification process GO:0006464 100 0.022
response to hexose GO:0009746 3 0.022
muscle organ development GO:0007517 101 0.022
regulation of cell activation GO:0050865 1 0.022
negative regulation of cellular metabolic process GO:0031324 77 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
regulation of apoptotic process GO:0042981 98 0.022
gtp metabolic process GO:0046039 4 0.021
response to monosaccharide GO:0034284 3 0.021
dicarboxylic acid transport GO:0006835 1 0.021
negative regulation of defense response GO:0031348 2 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
kidney development GO:0001822 92 0.021
nephron epithelium morphogenesis GO:0072088 1 0.021
hemopoiesis GO:0030097 183 0.021
blood vessel development GO:0001568 246 0.021
regulation of rna metabolic process GO:0051252 224 0.021
regulation of tube size GO:0035150 2 0.020
tissue remodeling GO:0048771 4 0.020
myeloid leukocyte migration GO:0097529 12 0.020
sensory system development GO:0048880 76 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
membrane invagination GO:0010324 1 0.020
response to endogenous stimulus GO:0009719 83 0.020
secondary metabolic process GO:0019748 3 0.020
regulation of protein catabolic process GO:0042176 1 0.020
specification of symmetry GO:0009799 204 0.020
response to organic cyclic compound GO:0014070 51 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.020
cognition GO:0050890 1 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
programmed cell death GO:0012501 119 0.019
regulation of programmed cell death GO:0043067 101 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
taxis GO:0042330 109 0.019
system process GO:0003008 185 0.019
stem cell development GO:0048864 82 0.019
multicellular organism growth GO:0035264 4 0.019
regulation of transcription dna templated GO:0006355 213 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
macromolecule localization GO:0033036 54 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.018
regulation of metal ion transport GO:0010959 4 0.018
negative regulation of signaling GO:0023057 96 0.018
lateral line development GO:0048882 66 0.018
cellular carbohydrate metabolic process GO:0044262 4 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.018
positive regulation of transcription dna templated GO:0045893 57 0.018
cell morphogenesis GO:0000902 289 0.018
regulation of binding GO:0051098 3 0.018
determination of left right symmetry GO:0007368 179 0.018
neutrophil migration GO:1990266 10 0.018
digestive tract morphogenesis GO:0048546 231 0.018
response to amino acid GO:0043200 2 0.018
neuron projection morphogenesis GO:0048812 161 0.018
negative regulation of stem cell differentiation GO:2000737 2 0.018
sensory perception of chemical stimulus GO:0007606 3 0.017
response to carbohydrate GO:0009743 3 0.017
meiotic nuclear division GO:0007126 4 0.017
neuron differentiation GO:0030182 353 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
eye development GO:0001654 277 0.017
regulation of reproductive process GO:2000241 4 0.017
antimicrobial humoral response GO:0019730 2 0.017
regulation of circadian sleep wake cycle GO:0042749 1 0.017
mesenchymal cell differentiation GO:0048762 87 0.016
regulation of neurogenesis GO:0050767 87 0.016
positive regulation of nucleic acid templated transcription GO:1903508 57 0.016
granulocyte chemotaxis GO:0071621 11 0.016
cortical cytoskeleton organization GO:0030865 1 0.016
regulation of myotube differentiation GO:0010830 2 0.016
chordate embryonic development GO:0043009 271 0.016
camera type eye development GO:0043010 222 0.016
regulation of skeletal muscle tissue development GO:0048641 4 0.016
protein stabilization GO:0050821 2 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
multicellular organismal metabolic process GO:0044236 2 0.016
chemotaxis GO:0006935 104 0.016
odontogenesis of dentin containing tooth GO:0042475 1 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
negative regulation of cytokine production GO:0001818 1 0.016
regulation of multicellular organismal metabolic process GO:0044246 2 0.016
locomotion GO:0040011 313 0.016
sensory organ morphogenesis GO:0090596 200 0.016
zymogen activation GO:0031638 3 0.016
mesenchyme development GO:0060485 127 0.016
positive regulation of metabolic process GO:0009893 108 0.016
carbohydrate derivative metabolic process GO:1901135 61 0.016
entrainment of circadian clock GO:0009649 2 0.016
multicellular organismal macromolecule metabolic process GO:0044259 2 0.016
cellular ketone metabolic process GO:0042180 11 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
behavior GO:0007610 74 0.016
regulation of cellular component organization GO:0051128 86 0.016
response to glucose GO:0009749 3 0.016
response to vitamin GO:0033273 3 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
mesenchymal cell development GO:0014031 78 0.016
establishment of localization GO:0051234 244 0.015
circadian sleep wake cycle sleep GO:0050802 1 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
myotube differentiation GO:0014902 45 0.015
leukocyte chemotaxis GO:0030595 12 0.015
germ line stem cell maintenance GO:0030718 2 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
growth GO:0040007 174 0.015
keratinocyte differentiation GO:0030216 0 0.015
macromolecule modification GO:0043412 111 0.015
syncytium formation GO:0006949 12 0.015
rhombomere 5 development GO:0021571 4 0.015
response to hypoxia GO:0001666 25 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
b cell activation GO:0042113 2 0.015
phagocytosis GO:0006909 3 0.015
nucleic acid metabolic process GO:0090304 244 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
cellular response to nutrient levels GO:0031669 2 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
negative regulation of signal transduction GO:0009968 94 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
striated muscle cell differentiation GO:0051146 129 0.014
regulation of blood vessel size GO:0050880 2 0.014
cellular protein catabolic process GO:0044257 4 0.014
leukocyte migration GO:0050900 15 0.014
long chain fatty acid metabolic process GO:0001676 1 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
lateral line system development GO:0048925 76 0.014
multi organism process GO:0051704 134 0.014
negative regulation of transcription dna templated GO:0045892 45 0.014
response to xenobiotic stimulus GO:0009410 45 0.014
regulation of protein polymerization GO:0032271 2 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
phosphatidylinositol mediated signaling GO:0048015 2 0.014
negative regulation of rna biosynthetic process GO:1902679 45 0.014
ear development GO:0043583 127 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
cellular response to stress GO:0033554 62 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
pectoral fin development GO:0033339 50 0.014
negative regulation of biosynthetic process GO:0009890 55 0.014
positive regulation of cell adhesion GO:0045785 1 0.013
morphogenesis of an epithelial sheet GO:0002011 49 0.013
response to lipid GO:0033993 60 0.013
immune system development GO:0002520 191 0.013
regulation of cell cycle GO:0051726 52 0.013
inorganic anion transport GO:0015698 25 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
regulation of cell morphogenesis GO:0022604 42 0.013
negative regulation of cellular biosynthetic process GO:0031327 55 0.013
mononuclear cell proliferation GO:0032943 1 0.013
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
regulation of dendrite development GO:0050773 3 0.013
myeloid cell differentiation GO:0030099 86 0.013
alcohol biosynthetic process GO:0046165 2 0.013
adult behavior GO:0030534 2 0.013
fin morphogenesis GO:0033334 53 0.013
cell death GO:0008219 121 0.013
peripheral nervous system development GO:0007422 55 0.013
positive regulation of protein kinase b signaling GO:0051897 1 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
response to other organism GO:0051707 97 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.012
axonogenesis GO:0007409 152 0.012
mechanosensory behavior GO:0007638 2 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
adherens junction assembly GO:0034333 1 0.012
connective tissue development GO:0061448 99 0.012
angiogenesis GO:0001525 158 0.012
cell substrate adhesion GO:0031589 4 0.012
adherens junction organization GO:0034332 4 0.012
neuroblast proliferation GO:0007405 2 0.012
spermatid development GO:0007286 2 0.012
regulation of cell differentiation GO:0045595 142 0.012
peptide metabolic process GO:0006518 1 0.012
positive regulation of cellular process GO:0048522 201 0.012
cellular protein metabolic process GO:0044267 129 0.012
sex determination GO:0007530 1 0.012
positive regulation of secretion GO:0051047 1 0.012
positive regulation of oocyte development GO:0060282 1 0.012
somatic muscle development GO:0007525 4 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
autophagy GO:0006914 4 0.012
stem cell division GO:0017145 1 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
regulation of primary metabolic process GO:0080090 311 0.012
regulation of axonogenesis GO:0050770 32 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
circadian sleep wake cycle GO:0042745 2 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
skeletal system development GO:0001501 181 0.012
death GO:0016265 121 0.012
circulatory system process GO:0003013 87 0.012
cell migration GO:0016477 237 0.012
protein polymerization GO:0051258 4 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
response to drug GO:0042493 3 0.011
protein polyubiquitination GO:0000209 4 0.011
otic vesicle formation GO:0030916 27 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
cell projection organization GO:0030030 284 0.011
muscle structure development GO:0061061 196 0.011
cytokine metabolic process GO:0042107 1 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
protein localization GO:0008104 40 0.011
lymphocyte proliferation GO:0046651 1 0.011
positive regulation of gene expression GO:0010628 71 0.011
catecholamine metabolic process GO:0006584 2 0.011
regulation of cell development GO:0060284 100 0.011
collagen metabolic process GO:0032963 2 0.011
regulation of skeletal muscle fiber development GO:0048742 2 0.011
ossification GO:0001503 23 0.011
hormone biosynthetic process GO:0042446 3 0.011
epithelial cell differentiation GO:0030855 116 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
regulation of epithelial to mesenchymal transition GO:0010717 3 0.011
regulation of signaling GO:0023051 235 0.011
regulation of synapse assembly GO:0051963 3 0.011
regulation of cell migration GO:0030334 40 0.011
protein acylation GO:0043543 3 0.011
segmentation GO:0035282 97 0.011
cellular response to starvation GO:0009267 1 0.011
regionalization GO:0003002 274 0.011
axon development GO:0061564 166 0.011
regulation of growth GO:0040008 42 0.011
toxin metabolic process GO:0009404 1 0.011
regulation of cell motility GO:2000145 46 0.011
renal system development GO:0072001 94 0.011
cellular component biogenesis GO:0044085 178 0.011
carbohydrate biosynthetic process GO:0016051 1 0.010
terpenoid metabolic process GO:0006721 15 0.010
regulation of lipid transport GO:0032368 4 0.010
somite development GO:0061053 96 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.010
circadian regulation of gene expression GO:0032922 8 0.010
anterior posterior pattern specification GO:0009952 152 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
positive regulation of rna biosynthetic process GO:1902680 57 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
myeloid cell development GO:0061515 32 0.010
spermatid differentiation GO:0048515 2 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010
regulation of transporter activity GO:0032409 2 0.010

sb:cb930 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.014
nervous system disease DOID:863 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
cardiovascular system disease DOID:1287 0 0.012