Danio rerio

0 known processes

sb:eu1555

sb:eu1555

sb:eu1555 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of gene expression GO:0010468 265 0.188
cell morphogenesis GO:0000902 289 0.122
cellular amine metabolic process GO:0044106 2 0.116
regulation of establishment of protein localization GO:0070201 4 0.115
nucleic acid templated transcription GO:0097659 181 0.100
positive regulation of transport GO:0051050 2 0.093
organic cyclic compound biosynthetic process GO:1901362 223 0.091
regulation of protein transport GO:0051223 3 0.089
rna metabolic process GO:0016070 219 0.088
regulation of cytokine production GO:0001817 3 0.087
regulation of developmental process GO:0050793 247 0.085
axon development GO:0061564 166 0.084
regulation of nucleic acid templated transcription GO:1903506 213 0.081
regulation of epithelial cell proliferation GO:0050678 3 0.074
larval development GO:0002164 2 0.072
embryonic organ development GO:0048568 381 0.070
regulation of transcription dna templated GO:0006355 213 0.066
embryo development ending in birth or egg hatching GO:0009792 271 0.065
biosynthetic process GO:0009058 294 0.061
negative regulation of biological process GO:0048519 304 0.059
heterocycle biosynthetic process GO:0018130 215 0.059
regulation of protein import into nucleus GO:0042306 2 0.058
cell projection organization GO:0030030 284 0.056
positive regulation of cytoskeleton organization GO:0051495 3 0.055
regulation of cellular amine metabolic process GO:0033238 0 0.054
positive regulation of cellular catabolic process GO:0031331 3 0.054
positive regulation of protein polymerization GO:0032273 2 0.053
embryonic organ morphogenesis GO:0048562 274 0.053
positive regulation of secretion by cell GO:1903532 1 0.052
regulation of macromolecule biosynthetic process GO:0010556 225 0.051
regulation of multicellular organismal development GO:2000026 223 0.051
intra s dna damage checkpoint GO:0031573 1 0.050
sensory organ development GO:0007423 393 0.049
single organism nuclear import GO:1902593 3 0.049
regulation of cellular metabolic process GO:0031323 320 0.048
transcription from rna polymerase ii promoter GO:0006366 80 0.048
nucleobase containing compound metabolic process GO:0006139 274 0.046
actin polymerization or depolymerization GO:0008154 2 0.046
regulation of stem cell differentiation GO:2000736 4 0.046
regulation of cytoplasmic transport GO:1903649 4 0.045
amine metabolic process GO:0009308 2 0.044
regulation of cell development GO:0060284 100 0.044
meiotic nuclear division GO:0007126 4 0.044
regulation of cellular amino acid metabolic process GO:0006521 0 0.043
blood vessel morphogenesis GO:0048514 216 0.043
nuclear transport GO:0051169 4 0.043
regulation of protein complex assembly GO:0043254 3 0.043
nucleic acid metabolic process GO:0090304 244 0.043
single organism localization GO:1902578 225 0.042
regulation of cell differentiation GO:0045595 142 0.041
neuron differentiation GO:0030182 353 0.041
synaptic growth at neuromuscular junction GO:0051124 2 0.040
aging GO:0007568 2 0.040
regulation of nitrogen compound metabolic process GO:0051171 251 0.039
regulation of anatomical structure morphogenesis GO:0022603 130 0.039
stem cell maintenance GO:0019827 4 0.039
regulation of binding GO:0051098 3 0.039
brain development GO:0007420 293 0.039
cellular component morphogenesis GO:0032989 336 0.038
chordate embryonic development GO:0043009 271 0.038
single organism organelle organization GO:1902589 199 0.037
heterocycle metabolic process GO:0046483 290 0.037
regulation of nervous system development GO:0051960 90 0.037
regulation of biosynthetic process GO:0009889 250 0.037
positive regulation of cellular component biogenesis GO:0044089 3 0.036
maintenance of location GO:0051235 4 0.036
germ line stem cell maintenance GO:0030718 2 0.035
generation of neurons GO:0048699 385 0.035
transcription dna templated GO:0006351 181 0.035
carboxylic acid metabolic process GO:0019752 22 0.035
regulation of signaling GO:0023051 235 0.035
cellular biosynthetic process GO:0044249 286 0.035
establishment of protein localization to organelle GO:0072594 4 0.034
head development GO:0060322 303 0.034
lateral inhibition GO:0046331 1 0.034
neuron projection development GO:0031175 180 0.034
positive regulation of biological process GO:0048518 253 0.034
regulation of protein polymerization GO:0032271 2 0.033
negative regulation of protein transport GO:0051224 3 0.033
digestive system development GO:0055123 289 0.033
pigmentation GO:0043473 85 0.033
regulation of epithelial to mesenchymal transition GO:0010717 3 0.033
nuclear import GO:0051170 3 0.032
positive regulation of cell cycle GO:0045787 3 0.032
protein import GO:0017038 3 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
protein polymerization GO:0051258 4 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
positive regulation of cytokine production GO:0001819 2 0.031
axonogenesis GO:0007409 152 0.030
regulation of protein targeting GO:1903533 2 0.030
negative regulation of multicellular organismal process GO:0051241 69 0.030
regulation of nucleocytoplasmic transport GO:0046822 2 0.030
regulation of rna biosynthetic process GO:2001141 213 0.030
regulation of cellular ketone metabolic process GO:0010565 7 0.030
regulation of protein localization to nucleus GO:1900180 2 0.029
cell projection morphogenesis GO:0048858 244 0.029
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.029
oxoacid metabolic process GO:0043436 31 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
positive regulation of catabolic process GO:0009896 4 0.029
regulation of cellular biosynthetic process GO:0031326 245 0.029
signal transduction GO:0007165 455 0.029
cellular aromatic compound metabolic process GO:0006725 295 0.029
neuron projection morphogenesis GO:0048812 161 0.029
regulation of intracellular protein transport GO:0033157 3 0.028
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.028
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.028
embryonic skeletal system development GO:0048706 97 0.028
protein secretion GO:0009306 1 0.027
regulation of rna metabolic process GO:0051252 224 0.027
nitrogen compound metabolic process GO:0006807 319 0.027
cell morphogenesis involved in differentiation GO:0000904 195 0.027
multicellular organism growth GO:0035264 4 0.027
histone h3 k4 methylation GO:0051568 2 0.026
rna biosynthetic process GO:0032774 181 0.026
positive regulation of secretion GO:0051047 1 0.026
cell part morphogenesis GO:0032990 246 0.026
cellular ketone metabolic process GO:0042180 11 0.026
transport GO:0006810 220 0.026
somatic stem cell maintenance GO:0035019 1 0.026
positive regulation of protein complex assembly GO:0031334 2 0.026
negative regulation of epithelial cell proliferation GO:0050680 1 0.026
carbohydrate homeostasis GO:0033500 1 0.025
multi organism process GO:0051704 134 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
protein localization to nucleus GO:0034504 3 0.025
cell cycle g1 s phase transition GO:0044843 1 0.025
response to external stimulus GO:0009605 264 0.025
cellular response to molecule of bacterial origin GO:0071219 3 0.025
protein acetylation GO:0006473 2 0.025
complement activation GO:0006956 3 0.024
spermatid development GO:0007286 2 0.024
single organism metabolic process GO:0044710 217 0.024
peptide transport GO:0015833 1 0.024
organic substance biosynthetic process GO:1901576 289 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
eye development GO:0001654 277 0.023
locomotion GO:0040011 313 0.023
regulation of synapse assembly GO:0051963 3 0.023
gene expression GO:0010467 252 0.023
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
cellular macromolecule biosynthetic process GO:0034645 224 0.022
protein import into nucleus GO:0006606 3 0.022
adult behavior GO:0030534 2 0.022
spermatid differentiation GO:0048515 2 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
protein targeting to nucleus GO:0044744 3 0.022
mitotic dna integrity checkpoint GO:0044774 4 0.022
regulation of metabolic process GO:0019222 359 0.022
regionalization GO:0003002 274 0.022
meiotic cell cycle process GO:1903046 3 0.022
amino acid transport GO:0006865 2 0.022
cellular amino acid metabolic process GO:0006520 7 0.021
positive regulation of biosynthetic process GO:0009891 68 0.021
wound healing GO:0042060 90 0.021
negative regulation of cellular process GO:0048523 283 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
mesenchymal cell differentiation GO:0048762 87 0.021
epithelial cell development GO:0002064 42 0.021
organic acid metabolic process GO:0006082 31 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
regulation of signal transduction GO:0009966 225 0.021
protein alkylation GO:0008213 13 0.021
regulation of cellular protein catabolic process GO:1903362 1 0.021
blood circulation GO:0008015 87 0.021
negative regulation of cytokine production GO:0001818 1 0.021
b cell activation GO:0042113 2 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
response to stress GO:0006950 263 0.020
regulation of response to stimulus GO:0048583 269 0.020
protein acylation GO:0043543 3 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
peptidyl lysine acetylation GO:0018394 2 0.020
cell motility GO:0048870 244 0.020
cellular component movement GO:0006928 335 0.020
bmp signaling pathway GO:0030509 52 0.020
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
negative regulation of stem cell differentiation GO:2000737 2 0.019
positive regulation of macromolecule metabolic process GO:0010604 93 0.019
angiogenesis GO:0001525 158 0.019
regulation of cell activation GO:0050865 1 0.019
glucose homeostasis GO:0042593 1 0.019
cell cycle arrest GO:0007050 1 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
lipid storage GO:0019915 1 0.018
response to abiotic stimulus GO:0009628 122 0.018
positive regulation of cellular process GO:0048522 201 0.018
urogenital system development GO:0001655 97 0.018
sequestering of metal ion GO:0051238 3 0.018
regulation of protein catabolic process GO:0042176 1 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
hatching GO:0035188 4 0.018
dorsal ventral pattern formation GO:0009953 125 0.018
gtp metabolic process GO:0046039 4 0.018
skeletal system development GO:0001501 181 0.018
regulation of cellular component organization GO:0051128 86 0.018
cell proliferation GO:0008283 80 0.018
regulation of localization GO:0032879 104 0.018
meiotic chromosome segregation GO:0045132 3 0.018
heart development GO:0007507 313 0.018
gland development GO:0048732 143 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
striated muscle tissue development GO:0014706 110 0.017
protein complex subunit organization GO:0071822 46 0.017
vasculature development GO:0001944 278 0.017
stem cell differentiation GO:0048863 117 0.017
embryonic skeletal system morphogenesis GO:0048704 93 0.017
regulation of cell morphogenesis GO:0022604 42 0.017
neuron development GO:0048666 262 0.017
covalent chromatin modification GO:0016569 20 0.017
growth GO:0040007 174 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
negative regulation of protein localization to nucleus GO:1900181 2 0.017
ventricular cardiac muscle tissue development GO:0003229 3 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
regulation of striated muscle contraction GO:0006942 2 0.016
regulation of metal ion transport GO:0010959 4 0.016
negative regulation of cytoplasmic transport GO:1903650 2 0.016
regulation of immune response GO:0050776 14 0.016
central nervous system development GO:0007417 387 0.016
protein complex localization GO:0031503 1 0.016
regulation of muscle contraction GO:0006937 3 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
tube morphogenesis GO:0035239 349 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
cellular response to external stimulus GO:0071496 2 0.016
regulation of gene expression epigenetic GO:0040029 11 0.016
retina development in camera type eye GO:0060041 146 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
chromatin modification GO:0016568 21 0.016
immune system process GO:0002376 241 0.016
response to radiation GO:0009314 51 0.015
cell cycle GO:0007049 93 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
actin filament based process GO:0030029 64 0.015
organelle organization GO:0006996 227 0.015
cognition GO:0050890 1 0.015
negative regulation of signal transduction GO:0009968 94 0.015
cell migration GO:0016477 237 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
autophagy GO:0006914 4 0.015
renal system development GO:0072001 94 0.015
cellular response to oxygen levels GO:0071453 1 0.015
negative regulation of signaling GO:0023057 96 0.015
regulation of primary metabolic process GO:0080090 311 0.015
digestive tract development GO:0048565 265 0.015
negative regulation of cell communication GO:0010648 96 0.014
reproduction GO:0000003 40 0.014
regulation of reproductive process GO:2000241 4 0.014
embryonic cranial skeleton morphogenesis GO:0048701 90 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
cellular protein catabolic process GO:0044257 4 0.014
organism emergence from protective structure GO:0071684 4 0.014
rna localization GO:0006403 4 0.014
establishment of localization in cell GO:0051649 77 0.014
developmental growth GO:0048589 166 0.014
regulation of cell communication GO:0010646 232 0.014
cellular response to starvation GO:0009267 1 0.014
protein modification process GO:0036211 100 0.014
sensory organ morphogenesis GO:0090596 200 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
regulation of skeletal muscle fiber development GO:0048742 2 0.014
regulation of response to nutrient levels GO:0032107 1 0.013
epithelial to mesenchymal transition GO:0001837 21 0.013
hormone transport GO:0009914 2 0.013
single organism transport GO:0044765 206 0.013
positive regulation of immune effector process GO:0002699 3 0.013
extracellular structure organization GO:0043062 27 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
cellular component biogenesis GO:0044085 178 0.013
homeostatic process GO:0042592 142 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
cellular component assembly GO:0022607 170 0.013
regulation of neurogenesis GO:0050767 87 0.013
anterior posterior pattern specification GO:0009952 152 0.013
skeletal system morphogenesis GO:0048705 102 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
system process GO:0003008 185 0.013
cytokinesis GO:0000910 3 0.013
b cell differentiation GO:0030183 1 0.013
response to carbohydrate GO:0009743 3 0.013
establishment of localization GO:0051234 244 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
sex determination GO:0007530 1 0.013
gtp catabolic process GO:0006184 2 0.013
response to nutrient GO:0007584 3 0.012
wnt signaling pathway GO:0016055 80 0.012
neurotransmitter secretion GO:0007269 2 0.012
regulation of calcium ion transport GO:0051924 2 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
regulation of cell proliferation GO:0042127 37 0.012
positive regulation of cell activation GO:0050867 1 0.012
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.012
death GO:0016265 121 0.012
protein metabolic process GO:0019538 183 0.012
positive regulation of multi organism process GO:0043902 3 0.012
regulation of cytokine biosynthetic process GO:0042035 1 0.012
positive regulation of gene expression GO:0010628 71 0.012
peptidyl serine modification GO:0018209 2 0.012
response to monosaccharide GO:0034284 3 0.012
regulation of myotube differentiation GO:0010830 2 0.012
microtubule based process GO:0007017 60 0.012
cellular response to radiation GO:0071478 4 0.012
chromatin organization GO:0006325 22 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
stem cell proliferation GO:0072089 4 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
hormone secretion GO:0046879 2 0.012
developmental maturation GO:0021700 34 0.012
regulation of molecular function GO:0065009 70 0.012
negative regulation of secretion by cell GO:1903531 2 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
regulation of tube size GO:0035150 2 0.012
muscle structure development GO:0061061 196 0.012
gastrulation GO:0007369 208 0.012
regulation of wnt signaling pathway GO:0030111 53 0.012
macromolecule modification GO:0043412 111 0.012
locomotor rhythm GO:0045475 3 0.012
regulation of cell shape GO:0008360 1 0.012
cytoskeleton organization GO:0007010 96 0.011
cellular response to organic substance GO:0071310 105 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
regulation of cell death GO:0010941 103 0.011
response to amino acid GO:0043200 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
response to chemical GO:0042221 320 0.011
mesenchyme development GO:0060485 127 0.011
membrane invagination GO:0010324 1 0.011
keratinocyte differentiation GO:0030216 0 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
inner ear development GO:0048839 126 0.011
regulation of epidermis development GO:0045682 2 0.011
cellular component disassembly GO:0022411 1 0.011
endosomal transport GO:0016197 2 0.011
negative regulation of developmental process GO:0051093 65 0.011
protein stabilization GO:0050821 2 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
actin filament organization GO:0007015 15 0.011
phagocytosis engulfment GO:0006911 1 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
ear development GO:0043583 127 0.011
stem cell development GO:0048864 82 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
inner ear morphogenesis GO:0042472 63 0.011
negative regulation of gene expression GO:0010629 65 0.011
smooth muscle contraction GO:0006939 2 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
epithelial cell differentiation GO:0030855 116 0.011
regulation of synapse organization GO:0050807 3 0.011
muscle organ development GO:0007517 101 0.011
regulation of neuron differentiation GO:0045664 56 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
regulation of blood vessel size GO:0050880 2 0.011
negative regulation of cell cycle GO:0045786 14 0.011
response to topologically incorrect protein GO:0035966 2 0.011
collagen biosynthetic process GO:0032964 2 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
cellular response to hypoxia GO:0071456 1 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.011
mononuclear cell proliferation GO:0032943 1 0.011
response to alkaloid GO:0043279 2 0.011
centrosome organization GO:0051297 1 0.010
mesenchymal cell development GO:0014031 78 0.010
ubiquitin dependent protein catabolic process GO:0006511 3 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
regulation of multicellular organism growth GO:0040014 4 0.010
actin cytoskeleton organization GO:0030036 63 0.010
muscle cell differentiation GO:0042692 139 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
organic substance transport GO:0071702 58 0.010

sb:eu1555 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.025
disease of anatomical entity DOID:7 0 0.020
cancer DOID:162 0 0.017
musculoskeletal system disease DOID:17 0 0.012
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.011