Danio rerio

0 known processes

sb:eu2436

sb:eu2436

sb:eu2436 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.227
neuron differentiation GO:0030182 353 0.110
post embryonic organ development GO:0048569 4 0.099
regulation of anatomical structure morphogenesis GO:0022603 130 0.088
regulation of macromolecule metabolic process GO:0060255 317 0.083
regulation of response to stimulus GO:0048583 269 0.082
cellular macromolecule metabolic process GO:0044260 391 0.081
regulation of primary metabolic process GO:0080090 311 0.081
tube morphogenesis GO:0035239 349 0.079
positive regulation of cellular component biogenesis GO:0044089 3 0.076
regulation of signaling GO:0023051 235 0.075
cell surface receptor signaling pathway GO:0007166 325 0.074
regulation of multicellular organismal process GO:0051239 277 0.069
regulation of cell differentiation GO:0045595 142 0.067
brain development GO:0007420 293 0.066
compound eye development GO:0048749 2 0.065
signal transduction GO:0007165 455 0.063
sensory organ development GO:0007423 393 0.061
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.060
response to organic substance GO:0010033 153 0.058
organic cyclic compound metabolic process GO:1901360 301 0.058
cellular biosynthetic process GO:0044249 286 0.058
regulation of developmental process GO:0050793 247 0.057
generation of neurons GO:0048699 385 0.055
morphogenesis of an epithelium GO:0002009 333 0.053
digestive tract morphogenesis GO:0048546 231 0.053
cellular component morphogenesis GO:0032989 336 0.052
neuron development GO:0048666 262 0.052
multicellular organism growth GO:0035264 4 0.051
nucleic acid metabolic process GO:0090304 244 0.051
adherens junction organization GO:0034332 4 0.050
regulation of cellular metabolic process GO:0031323 320 0.047
nucleic acid templated transcription GO:0097659 181 0.046
regulation of gene expression GO:0010468 265 0.046
response to chemical GO:0042221 320 0.045
negative regulation of protein phosphorylation GO:0001933 4 0.045
taxis GO:0042330 109 0.045
stem cell proliferation GO:0072089 4 0.043
negative regulation of cellular process GO:0048523 283 0.043
regulation of multicellular organismal development GO:2000026 223 0.043
positive regulation of protein complex assembly GO:0031334 2 0.043
regulation of metabolic process GO:0019222 359 0.043
cellular protein metabolic process GO:0044267 129 0.041
macromolecule modification GO:0043412 111 0.041
protein metabolic process GO:0019538 183 0.041
phagocytosis GO:0006909 3 0.040
actin filament polymerization GO:0030041 2 0.040
central nervous system development GO:0007417 387 0.040
maintenance of location GO:0051235 4 0.039
hepaticobiliary system development GO:0061008 98 0.039
vasculature development GO:0001944 278 0.039
sensory organ morphogenesis GO:0090596 200 0.039
dorsal ventral pattern formation GO:0009953 125 0.038
gland development GO:0048732 143 0.038
transport GO:0006810 220 0.038
cellular response to external stimulus GO:0071496 2 0.038
protein modification process GO:0036211 100 0.037
nitrogen compound metabolic process GO:0006807 319 0.037
digestive system development GO:0055123 289 0.037
single organism localization GO:1902578 225 0.036
positive regulation of catabolic process GO:0009896 4 0.036
regulation of multicellular organism growth GO:0040014 4 0.036
blood vessel morphogenesis GO:0048514 216 0.036
negative chemotaxis GO:0050919 1 0.035
muscle cell differentiation GO:0042692 139 0.035
regionalization GO:0003002 274 0.035
transcription dna templated GO:0006351 181 0.035
regulation of biological quality GO:0065008 263 0.035
regulation of signal transduction GO:0009966 225 0.035
cilium morphogenesis GO:0060271 85 0.035
heart development GO:0007507 313 0.034
nucleocytoplasmic transport GO:0006913 4 0.034
head development GO:0060322 303 0.034
regulation of protein polymerization GO:0032271 2 0.034
response to stress GO:0006950 263 0.034
cellular protein modification process GO:0006464 100 0.034
muscle cell development GO:0055001 115 0.033
kidney development GO:0001822 92 0.033
positive regulation of cytoskeleton organization GO:0051495 3 0.033
digestive tract development GO:0048565 265 0.033
organonitrogen compound metabolic process GO:1901564 74 0.033
aging GO:0007568 2 0.033
liver development GO:0001889 96 0.032
enzyme linked receptor protein signaling pathway GO:0007167 106 0.032
angiogenesis GO:0001525 158 0.032
nuclear transport GO:0051169 4 0.032
positive regulation of map kinase activity GO:0043406 3 0.032
aromatic compound biosynthetic process GO:0019438 217 0.032
mitochondrion organization GO:0007005 4 0.031
protein polymerization GO:0051258 4 0.031
ameboidal type cell migration GO:0001667 143 0.031
regulation of biosynthetic process GO:0009889 250 0.031
regulation of cytokine production GO:0001817 3 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
branching morphogenesis of a nerve GO:0048755 4 0.031
striated muscle cell development GO:0055002 108 0.030
actin polymerization or depolymerization GO:0008154 2 0.030
organelle organization GO:0006996 227 0.030
regulation of wound healing GO:0061041 2 0.030
positive regulation of transport GO:0051050 2 0.030
eye development GO:0001654 277 0.030
erk1 and erk2 cascade GO:0070371 4 0.030
autophagy GO:0006914 4 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.029
chordate embryonic development GO:0043009 271 0.029
regulation of erk1 and erk2 cascade GO:0070372 4 0.029
embryonic organ morphogenesis GO:0048562 274 0.029
negative regulation of signal transduction GO:0009968 94 0.029
determination of bilateral symmetry GO:0009855 204 0.029
regulation of cell death GO:0010941 103 0.028
positive regulation of cell cycle GO:0045787 3 0.028
cellular component assembly GO:0022607 170 0.028
camera type eye development GO:0043010 222 0.028
embryonic organ development GO:0048568 381 0.028
mononuclear cell proliferation GO:0032943 1 0.028
cellular response to extracellular stimulus GO:0031668 2 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.027
regulation of cell communication GO:0010646 232 0.027
muscle tissue development GO:0060537 110 0.027
lipid catabolic process GO:0016042 4 0.027
negative regulation of biological process GO:0048519 304 0.027
response to hexose GO:0009746 3 0.027
positive regulation of biological process GO:0048518 253 0.027
protein localization to nucleus GO:0034504 3 0.027
regulation of nervous system development GO:0051960 90 0.026
glomerulus development GO:0032835 27 0.026
secondary metabolic process GO:0019748 3 0.026
cellular response to chemical stimulus GO:0070887 157 0.026
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.026
phosphate containing compound metabolic process GO:0006796 108 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
regulation of protein complex assembly GO:0043254 3 0.026
gene expression GO:0010467 252 0.026
skeletal system development GO:0001501 181 0.026
response to carbohydrate GO:0009743 3 0.026
single organism metabolic process GO:0044710 217 0.026
cell morphogenesis GO:0000902 289 0.026
positive regulation of immune effector process GO:0002699 3 0.026
organic cyclic compound biosynthetic process GO:1901362 223 0.026
chemotaxis GO:0006935 104 0.026
response to external stimulus GO:0009605 264 0.025
positive regulation of protein polymerization GO:0032273 2 0.025
positive regulation of cytokine production GO:0001819 2 0.025
stem cell maintenance GO:0019827 4 0.025
regulation of protein catabolic process GO:0042176 1 0.025
cellular component biogenesis GO:0044085 178 0.025
single organism transport GO:0044765 206 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
cell projection organization GO:0030030 284 0.024
cell motility GO:0048870 244 0.024
cell migration GO:0016477 237 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
rna metabolic process GO:0016070 219 0.024
mesoderm development GO:0007498 88 0.024
programmed cell death GO:0012501 119 0.024
immune system process GO:0002376 241 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
negative regulation of cytokine production GO:0001818 1 0.023
retina morphogenesis in camera type eye GO:0060042 79 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
cellular component movement GO:0006928 335 0.023
intracellular signal transduction GO:0035556 85 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
localization of cell GO:0051674 244 0.023
blood vessel development GO:0001568 246 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.023
regulation of cellular component organization GO:0051128 86 0.022
positive regulation of cellular process GO:0048522 201 0.022
cellular response to biotic stimulus GO:0071216 3 0.022
response to monosaccharide GO:0034284 3 0.022
urogenital system development GO:0001655 97 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
regeneration GO:0031099 91 0.021
negative regulation of metabolic process GO:0009892 86 0.021
organic substance biosynthetic process GO:1901576 289 0.021
cell part morphogenesis GO:0032990 246 0.021
gtp metabolic process GO:0046039 4 0.021
regulation of cell activation GO:0050865 1 0.021
regulation of cell development GO:0060284 100 0.021
regulation of protein targeting GO:1903533 2 0.021
cellular response to starvation GO:0009267 1 0.021
mesenchyme development GO:0060485 127 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
actin filament based process GO:0030029 64 0.020
lateral inhibition GO:0046331 1 0.020
somatic muscle development GO:0007525 4 0.020
regulation of neurogenesis GO:0050767 87 0.020
cellular ketone metabolic process GO:0042180 11 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
cell projection morphogenesis GO:0048858 244 0.020
positive regulation of cell activation GO:0050867 1 0.020
regulation of embryonic development GO:0045995 47 0.020
cellular response to organic substance GO:0071310 105 0.020
negative regulation of signaling GO:0023057 96 0.020
cell cell signaling GO:0007267 52 0.020
connective tissue development GO:0061448 99 0.020
activation of mapk activity GO:0000187 3 0.020
amine metabolic process GO:0009308 2 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.019
stem cell differentiation GO:0048863 117 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
protein import GO:0017038 3 0.019
female gonad development GO:0008585 4 0.019
lipid storage GO:0019915 1 0.019
cellular response to nutrient levels GO:0031669 2 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
nuclear import GO:0051170 3 0.019
gtp catabolic process GO:0006184 2 0.019
i kappab kinase nf kappab signaling GO:0007249 4 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.019
neuron projection development GO:0031175 180 0.019
response to bacterium GO:0009617 58 0.019
renal system development GO:0072001 94 0.019
meiotic nuclear division GO:0007126 4 0.018
cell fate commitment GO:0045165 99 0.018
biosynthetic process GO:0009058 294 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
locomotion GO:0040011 313 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
regulation of cell shape GO:0008360 1 0.018
fin regeneration GO:0031101 51 0.018
developmental growth GO:0048589 166 0.018
muscle structure development GO:0061061 196 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
heterocycle metabolic process GO:0046483 290 0.018
specification of symmetry GO:0009799 204 0.018
actin cytoskeleton organization GO:0030036 63 0.018
phosphorus metabolic process GO:0006793 109 0.018
wound healing GO:0042060 90 0.018
muscle fiber development GO:0048747 52 0.018
regulation of anatomical structure size GO:0090066 33 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.017
immune system development GO:0002520 191 0.017
cartilage development GO:0051216 96 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
establishment of localization GO:0051234 244 0.017
adherens junction assembly GO:0034333 1 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
gastrulation GO:0007369 208 0.017
outflow tract morphogenesis GO:0003151 1 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
pronephros development GO:0048793 69 0.017
growth GO:0040007 174 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
regulation of localization GO:0032879 104 0.017
small molecule metabolic process GO:0044281 77 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
embryonic heart tube development GO:0035050 133 0.017
camera type eye morphogenesis GO:0048593 108 0.017
system process GO:0003008 185 0.016
glucose homeostasis GO:0042593 1 0.016
positive regulation of jnk cascade GO:0046330 3 0.016
regulation of inflammatory response GO:0050727 2 0.016
skeletal muscle tissue development GO:0007519 67 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
multi organism process GO:0051704 134 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
leukocyte proliferation GO:0070661 1 0.016
peptide transport GO:0015833 1 0.016
negative regulation of multicellular organismal process GO:0051241 69 0.016
membrane invagination GO:0010324 1 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
rna biosynthetic process GO:0032774 181 0.016
regulation of protein transport GO:0051223 3 0.016
cellular amine metabolic process GO:0044106 2 0.016
cell proliferation GO:0008283 80 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
response to wounding GO:0009611 116 0.016
regulation of binding GO:0051098 3 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
organic acid metabolic process GO:0006082 31 0.015
neuron projection morphogenesis GO:0048812 161 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
forebrain development GO:0030900 96 0.015
axon development GO:0061564 166 0.015
segmentation GO:0035282 97 0.015
response to external biotic stimulus GO:0043207 97 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
single organism organelle organization GO:1902589 199 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
epiboly GO:0090504 41 0.015
phosphorylation GO:0016310 69 0.015
production of molecular mediator of immune response GO:0002440 2 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
neuron projection guidance GO:0097485 86 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
extracellular matrix organization GO:0030198 27 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
macromolecule localization GO:0033036 54 0.014
melanin metabolic process GO:0006582 2 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
axonogenesis GO:0007409 152 0.014
regulation of apoptotic process GO:0042981 98 0.014
carbohydrate homeostasis GO:0033500 1 0.014
defense response to other organism GO:0098542 33 0.014
determination of left right symmetry GO:0007368 179 0.014
cellular localization GO:0051641 97 0.014
diencephalon development GO:0021536 58 0.014
regulation of programmed cell death GO:0043067 101 0.014
cell adhesion GO:0007155 40 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
regulation of wnt signaling pathway GO:0030111 53 0.013
synaptic target recognition GO:0008039 1 0.013
morphogenesis of an epithelial sheet GO:0002011 49 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
small molecule catabolic process GO:0044282 3 0.013
membrane fusion GO:0061025 2 0.013
single organism membrane fusion GO:0044801 2 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of reproductive process GO:2000241 4 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
cellular response to oxygen containing compound GO:1901701 20 0.013
mesenchymal cell development GO:0014031 78 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
protein secretion GO:0009306 1 0.013
regulation of autophagy GO:0010506 3 0.013
cell recognition GO:0008037 19 0.013
phagocytosis engulfment GO:0006911 1 0.013
retina development in camera type eye GO:0060041 146 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
regulation of molecular function GO:0065009 70 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
meiotic cell cycle process GO:1903046 3 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
positive regulation of biosynthetic process GO:0009891 68 0.013
protein phosphorylation GO:0006468 47 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
striated muscle cell differentiation GO:0051146 129 0.013
eye morphogenesis GO:0048592 144 0.013
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
cell substrate adhesion GO:0031589 4 0.013
response to other organism GO:0051707 97 0.013
oxoacid metabolic process GO:0043436 31 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of cell projection assembly GO:0060491 4 0.012
immune response GO:0006955 28 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
regulation of gtpase activity GO:0043087 2 0.012
tissue regeneration GO:0042246 74 0.012
cell chemotaxis GO:0060326 17 0.012
death GO:0016265 121 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
regulation of neuron differentiation GO:0045664 56 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
positive regulation of molecular function GO:0044093 33 0.012
positive regulation of developmental process GO:0051094 50 0.012
protein localization to plasma membrane GO:0072659 1 0.012
extracellular structure organization GO:0043062 27 0.012
response to growth factor GO:0070848 39 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
lymphocyte proliferation GO:0046651 1 0.012
germ line stem cell maintenance GO:0030718 2 0.012
glial cell migration GO:0008347 3 0.012
female sex differentiation GO:0046660 4 0.012
spermatid differentiation GO:0048515 2 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
protein targeting to nucleus GO:0044744 3 0.012
fin development GO:0033333 77 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
cellular protein catabolic process GO:0044257 4 0.012
response to nutrient GO:0007584 3 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
defense response to bacterium GO:0042742 22 0.011
positive regulation of secretion GO:0051047 1 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
tube closure GO:0060606 1 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
neuroblast proliferation GO:0007405 2 0.011
response to oxygen containing compound GO:1901700 55 0.011
regulation of organ growth GO:0046620 3 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
negative regulation of kinase activity GO:0033673 4 0.011
regulation of axonogenesis GO:0050770 32 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
protein complex localization GO:0031503 1 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
axon guidance GO:0007411 86 0.011
response to uv GO:0009411 3 0.011
negative regulation of cell communication GO:0010648 96 0.011
cranial nerve development GO:0021545 42 0.011
skeletal system morphogenesis GO:0048705 102 0.011
pectoral fin development GO:0033339 50 0.011
primary neural tube formation GO:0014020 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of mrna processing GO:0050684 3 0.011
establishment of localization in cell GO:0051649 77 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
tissue remodeling GO:0048771 4 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
adult behavior GO:0030534 2 0.011
homeostatic process GO:0042592 142 0.011
neuron recognition GO:0008038 18 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
positive regulation of secretion by cell GO:1903532 1 0.010
neural retina development GO:0003407 49 0.010
golgi vesicle transport GO:0048193 3 0.010
positive regulation of transcription dna templated GO:0045893 57 0.010
developmental cell growth GO:0048588 52 0.010
positive regulation of metabolic process GO:0009893 108 0.010
modification dependent protein catabolic process GO:0019941 3 0.010
regulation of phosphorus metabolic process GO:0051174 43 0.010
cell death GO:0008219 121 0.010
wnt signaling pathway GO:0016055 80 0.010
regulation of protein metabolic process GO:0051246 56 0.010
forebrain cell migration GO:0021885 1 0.010
cortical actin cytoskeleton organization GO:0030866 1 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
peptidyl serine modification GO:0018209 2 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
positive regulation of translation GO:0045727 1 0.010
antimicrobial humoral response GO:0019730 2 0.010
nerve development GO:0021675 45 0.010

sb:eu2436 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.033
musculoskeletal system disease DOID:17 0 0.024
sensory system disease DOID:0050155 0 0.022
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.016
connective tissue disease DOID:65 0 0.013
bone development disease DOID:0080006 0 0.011
bone disease DOID:0080001 0 0.011