Danio rerio

30 known processes

scn1bb

sodium channel, voltage-gated, type I, beta b

scn1bb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.906
neuromast development GO:0048884 46 0.790
lateral line development GO:0048882 66 0.758
lateral line system development GO:0048925 76 0.637
embryonic cranial skeleton morphogenesis GO:0048701 90 0.500
sensory system development GO:0048880 76 0.491
membrane repolarization GO:0086009 2 0.479
inner ear receptor stereocilium organization GO:0060122 8 0.441
eye development GO:0001654 277 0.430
mechanosensory lateral line system development GO:0048881 49 0.411
hair cell differentiation GO:0035315 32 0.278
regulation of multicellular organismal process GO:0051239 277 0.266
camera type eye development GO:0043010 222 0.229
regulation of jak stat cascade GO:0046425 3 0.226
eye morphogenesis GO:0048592 144 0.215
cilium assembly GO:0042384 58 0.209
cell migration GO:0016477 237 0.192
embryonic organ morphogenesis GO:0048562 274 0.185
cellular component movement GO:0006928 335 0.181
inner ear receptor cell development GO:0060119 20 0.178
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.169
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.165
skeletal system development GO:0001501 181 0.160
cilium organization GO:0044782 71 0.157
sensory organ morphogenesis GO:0090596 200 0.149
regulation of membrane repolarization GO:0060306 1 0.145
embryonic organ development GO:0048568 381 0.139
cell projection morphogenesis GO:0048858 244 0.138
tyrosine phosphorylation of stat protein GO:0007260 1 0.126
neuron differentiation GO:0030182 353 0.123
detection of mechanical stimulus GO:0050982 11 0.122
neuron development GO:0048666 262 0.118
cell projection assembly GO:0030031 64 0.109
morphogenesis of an epithelium GO:0002009 333 0.107
nerve development GO:0021675 45 0.101
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.100
determination of bilateral symmetry GO:0009855 204 0.094
posterior lateral line system development GO:0048915 46 0.092
microtubule based movement GO:0007018 33 0.091
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.088
tube morphogenesis GO:0035239 349 0.086
neuromuscular process controlling balance GO:0050885 3 0.085
regulation of response to cytokine stimulus GO:0060759 3 0.080
cellular component assembly GO:0022607 170 0.080
cell motility GO:0048870 244 0.077
regulation of cellular amine metabolic process GO:0033238 0 0.077
embryonic skeletal system morphogenesis GO:0048704 93 0.076
cell projection organization GO:0030030 284 0.074
jak stat cascade GO:0007259 5 0.071
microtubule based process GO:0007017 60 0.070
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.066
epithelial tube morphogenesis GO:0060562 148 0.062
oxoacid metabolic process GO:0043436 31 0.062
neuron projection development GO:0031175 180 0.062
epithelial cilium movement GO:0003351 15 0.061
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.059
posterior lateral line development GO:0048916 38 0.058
equilibrioception GO:0050957 2 0.058
regulation of cellular component organization GO:0051128 86 0.057
regulation of cellular amino acid metabolic process GO:0006521 0 0.057
localization of cell GO:0051674 244 0.056
multicellular organism growth GO:0035264 4 0.056
heart development GO:0007507 313 0.054
establishment of monopolar cell polarity GO:0061162 2 0.053
inner ear receptor cell differentiation GO:0060113 29 0.053
regulation of reproductive process GO:2000241 4 0.053
cellular amine metabolic process GO:0044106 2 0.053
response to drug GO:0042493 3 0.051
locomotion GO:0040011 313 0.051
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.050
cellular component biogenesis GO:0044085 178 0.050
growth GO:0040007 174 0.049
inner ear development GO:0048839 126 0.049
convergent extension involved in gastrulation GO:0060027 71 0.049
chemotaxis GO:0006935 104 0.047
camera type eye morphogenesis GO:0048593 108 0.045
amine metabolic process GO:0009308 2 0.044
positive regulation of cellular amine metabolic process GO:0033240 0 0.043
auditory receptor cell development GO:0060117 8 0.043
cranial nerve development GO:0021545 42 0.043
synaptic growth at neuromuscular junction GO:0051124 2 0.043
regulation of photoreceptor cell differentiation GO:0046532 2 0.042
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.042
biosynthetic process GO:0009058 294 0.041
skeletal system morphogenesis GO:0048705 102 0.040
larval development GO:0002164 2 0.040
skin development GO:0043588 54 0.040
embryonic skeletal system development GO:0048706 97 0.040
blood vessel morphogenesis GO:0048514 216 0.039
heart morphogenesis GO:0003007 156 0.039
sodium ion transport GO:0006814 24 0.039
regulation of biological quality GO:0065008 263 0.038
developmental programmed cell death GO:0010623 4 0.038
cellular component assembly involved in morphogenesis GO:0010927 107 0.038
cilium movement GO:0003341 26 0.037
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.037
axon development GO:0061564 166 0.037
positive regulation of developmental process GO:0051094 50 0.037
regulation of cell differentiation GO:0045595 142 0.037
auditory receptor cell morphogenesis GO:0002093 4 0.036
mechanoreceptor differentiation GO:0042490 37 0.036
ectoderm development GO:0007398 9 0.036
kidney development GO:0001822 92 0.035
inner ear morphogenesis GO:0042472 63 0.034
vasculature development GO:0001944 278 0.034
anatomical structure arrangement GO:0048532 2 0.034
retina development in camera type eye GO:0060041 146 0.034
retina morphogenesis in camera type eye GO:0060042 79 0.034
synaptic vesicle localization GO:0097479 1 0.034
small molecule metabolic process GO:0044281 77 0.032
astrocyte differentiation GO:0048708 1 0.032
convergent extension GO:0060026 118 0.032
positive regulation of signaling GO:0023056 56 0.032
positive regulation of gliogenesis GO:0014015 2 0.032
peripheral nervous system development GO:0007422 55 0.032
regulation of glial cell differentiation GO:0045685 4 0.031
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.031
positive regulation of gene expression GO:0010628 71 0.031
mesenchymal cell development GO:0014031 78 0.031
organelle assembly GO:0070925 110 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.029
regulation of multicellular organismal development GO:2000026 223 0.029
positive regulation of cellular process GO:0048522 201 0.029
regulation of retina development in camera type eye GO:1902866 2 0.029
cell surface receptor signaling pathway GO:0007166 325 0.029
ear development GO:0043583 127 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.028
determination of left right symmetry GO:0007368 179 0.028
immune system development GO:0002520 191 0.028
adherens junction maintenance GO:0034334 2 0.028
organic substance biosynthetic process GO:1901576 289 0.028
negative regulation of response to cytokine stimulus GO:0060761 2 0.028
cellular ketone metabolic process GO:0042180 11 0.028
cell part morphogenesis GO:0032990 246 0.027
cartilage development GO:0051216 96 0.027
chordate embryonic development GO:0043009 271 0.027
negative regulation of cell migration GO:0030336 17 0.027
regeneration GO:0031099 91 0.027
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.026
establishment of apical basal cell polarity GO:0035089 2 0.026
regulation of synapse assembly GO:0051963 3 0.026
leukocyte proliferation GO:0070661 1 0.026
cellular amino acid metabolic process GO:0006520 7 0.025
cell morphogenesis GO:0000902 289 0.025
auditory receptor cell differentiation GO:0042491 15 0.025
nucleoside monophosphate catabolic process GO:0009125 4 0.025
axonemal dynein complex assembly GO:0070286 5 0.025
polarized epithelial cell differentiation GO:0030859 4 0.025
developmental growth GO:0048589 166 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
cytokinesis GO:0000910 3 0.025
ameboidal type cell migration GO:0001667 143 0.024
regulation of cell communication GO:0010646 232 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
response to stress GO:0006950 263 0.024
cilium or flagellum dependent cell motility GO:0001539 4 0.024
regulation of cytokine production GO:0001817 3 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
specification of symmetry GO:0009799 204 0.023
startle response GO:0001964 4 0.023
cilium morphogenesis GO:0060271 85 0.023
taxis GO:0042330 109 0.023
regulation of metabolic process GO:0019222 359 0.023
peptidyl serine modification GO:0018209 2 0.022
blood vessel development GO:0001568 246 0.022
immune system process GO:0002376 241 0.022
positive regulation of jak stat cascade GO:0046427 2 0.022
fluid transport GO:0042044 17 0.022
regulation of transmembrane transporter activity GO:0022898 2 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
cilium movement involved in cell motility GO:0060294 3 0.021
gtp metabolic process GO:0046039 4 0.021
cardiac conduction GO:0061337 3 0.021
heart contraction GO:0060047 71 0.021
axonogenesis GO:0007409 152 0.021
neural crest cell development GO:0014032 62 0.021
protein import into nucleus GO:0006606 3 0.021
protein localization to nucleus GO:0034504 3 0.021
cell junction maintenance GO:0034331 2 0.021
cell morphogenesis involved in differentiation GO:0000904 195 0.021
angiogenesis GO:0001525 158 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
synaptic vesicle transport GO:0048489 1 0.020
neuroblast proliferation GO:0007405 2 0.020
cellular response to nutrient levels GO:0031669 2 0.020
fatty acid biosynthetic process GO:0006633 4 0.020
spermatid differentiation GO:0048515 2 0.020
atp catabolic process GO:0006200 4 0.020
exocytosis GO:0006887 1 0.020
aging GO:0007568 2 0.019
establishment of localization GO:0051234 244 0.019
regulation of synapse organization GO:0050807 3 0.019
organic acid metabolic process GO:0006082 31 0.019
membrane fusion GO:0061025 2 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
positive regulation of catabolic process GO:0009896 4 0.019
synaptic vesicle recycling GO:0036465 1 0.019
negative regulation of cell motility GO:2000146 17 0.019
membrane hyperpolarization GO:0060081 1 0.019
regulation of cytokine mediated signaling pathway GO:0001959 3 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
establishment of organelle localization GO:0051656 45 0.019
anterior lateral line system development GO:0048898 9 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
heart looping GO:0001947 94 0.019
negative regulation of reproductive process GO:2000242 3 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
transmembrane transport GO:0055085 120 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
epidermal cell differentiation GO:0009913 36 0.018
regulation of nervous system development GO:0051960 90 0.018
cellular component morphogenesis GO:0032989 336 0.018
regulation of wnt signaling pathway GO:0030111 53 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.018
erythrocyte differentiation GO:0030218 54 0.018
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 1 0.018
regulation of protein transport GO:0051223 3 0.018
cellular component maintenance GO:0043954 3 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
positive regulation of cell differentiation GO:0045597 30 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
regulation of tube size GO:0035150 2 0.017
fin morphogenesis GO:0033334 53 0.017
epithelial cell differentiation GO:0030855 116 0.017
negative regulation of developmental process GO:0051093 65 0.017
regulation of transporter activity GO:0032409 2 0.017
positive regulation of multicellular organismal process GO:0051240 52 0.017
leukocyte differentiation GO:0002521 25 0.017
neuron projection guidance GO:0097485 86 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
regulation of neurogenesis GO:0050767 87 0.017
protein import GO:0017038 3 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
primary neural tube formation GO:0014020 1 0.016
regulation of neuron differentiation GO:0045664 56 0.016
long chain fatty acid metabolic process GO:0001676 1 0.016
determination of heart left right asymmetry GO:0061371 117 0.016
myeloid cell differentiation GO:0030099 86 0.016
regulation of cell motility GO:2000145 46 0.016
notch signaling pathway GO:0007219 35 0.016
tube closure GO:0060606 1 0.016
cell migration involved in gastrulation GO:0042074 79 0.015
regulation of developmental process GO:0050793 247 0.015
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.015
single organism membrane fusion GO:0044801 2 0.015
reflex GO:0060004 2 0.015
adult behavior GO:0030534 2 0.015
positive regulation of neuron projection regeneration GO:0070572 3 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
compound eye development GO:0048749 2 0.015
generation of neurons GO:0048699 385 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
negative regulation of cytokine production GO:0001818 1 0.015
action potential GO:0001508 19 0.015
regulation of neuron projection development GO:0010975 40 0.015
cellular macromolecule metabolic process GO:0044260 391 0.015
regulation of metal ion transport GO:0010959 4 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
establishment of cell polarity GO:0030010 18 0.014
protein targeting to nucleus GO:0044744 3 0.014
establishment or maintenance of monopolar cell polarity GO:0061339 2 0.014
energy reserve metabolic process GO:0006112 2 0.014
synaptic transmission GO:0007268 35 0.014
cell growth GO:0016049 57 0.014
mitochondrion organization GO:0007005 4 0.014
alcohol biosynthetic process GO:0046165 2 0.014
stem cell proliferation GO:0072089 4 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
organelle localization GO:0051640 49 0.014
gene expression GO:0010467 252 0.014
digestive tract development GO:0048565 265 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
regulation of cell development GO:0060284 100 0.014
wound healing GO:0042060 90 0.013
cellular response to starvation GO:0009267 1 0.013
establishment of epithelial cell polarity GO:0090162 2 0.013
neuromast deposition GO:0048885 9 0.013
cellular protein modification process GO:0006464 100 0.013
regulation of postsynaptic membrane potential GO:0060078 1 0.013
establishment or maintenance of cell polarity GO:0007163 29 0.013
neurotransmitter transport GO:0006836 2 0.013
nitrogen compound metabolic process GO:0006807 319 0.013
single organism organelle organization GO:1902589 199 0.013
long chain fatty acid biosynthetic process GO:0042759 1 0.013
neuron projection morphogenesis GO:0048812 161 0.013
ion transport GO:0006811 114 0.013
positive regulation of nervous system development GO:0051962 25 0.013
neuromuscular process GO:0050905 7 0.013
regulation of gene expression GO:0010468 265 0.013
dicarboxylic acid transport GO:0006835 1 0.013
regulation of blood vessel size GO:0050880 2 0.013
organelle organization GO:0006996 227 0.013
apoptotic process involved in morphogenesis GO:0060561 2 0.012
response to wounding GO:0009611 116 0.012
regulation of cell activation GO:0050865 1 0.012
cellular protein metabolic process GO:0044267 129 0.012
lipid metabolic process GO:0006629 52 0.012
multicellular organismal signaling GO:0035637 22 0.012
detection of stimulus GO:0051606 29 0.012
response to steroid hormone GO:0048545 35 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
regulation of cellular component movement GO:0051270 55 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
embryonic eye morphogenesis GO:0048048 30 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
cell death GO:0008219 121 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
amino acid transport GO:0006865 2 0.011
canonical wnt signaling pathway GO:0060070 48 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
negative regulation of biological process GO:0048519 304 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
positive regulation of epithelial cell differentiation GO:0030858 2 0.011
sequestering of metal ion GO:0051238 3 0.011
melanin metabolic process GO:0006582 2 0.011
regulation of gliogenesis GO:0014013 6 0.011
striated muscle tissue development GO:0014706 110 0.011
negative regulation of cellular component movement GO:0051271 18 0.011
spermatid development GO:0007286 2 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
spindle localization GO:0051653 12 0.011
response to unfolded protein GO:0006986 2 0.011
post embryonic organ development GO:0048569 4 0.011
glial cell differentiation GO:0010001 42 0.011
regulation of heart growth GO:0060420 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
semicircular canal development GO:0060872 24 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
positive regulation of signal transduction GO:0009967 56 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
negative regulation of locomotion GO:0040013 18 0.010
cellular amide metabolic process GO:0043603 4 0.010
tissue migration GO:0090130 37 0.010
negative regulation of nucleic acid templated transcription GO:1903507 45 0.010
auditory receptor cell stereocilium organization GO:0060088 4 0.010
regulation of circadian rhythm GO:0042752 4 0.010
somite development GO:0061053 96 0.010
stem cell differentiation GO:0048863 117 0.010
melanocyte migration GO:0097324 4 0.010
cognition GO:0050890 1 0.010
head development GO:0060322 303 0.010
neural tube development GO:0021915 62 0.010
endoplasmic reticulum unfolded protein response GO:0030968 2 0.010
embryonic hemopoiesis GO:0035162 53 0.010

scn1bb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.024
disease of anatomical entity DOID:7 0 0.012
immune system disease DOID:2914 0 0.012
nervous system disease DOID:863 0 0.011