Danio rerio

0 known processes

scn3b

sodium channel, voltage-gated, type III, beta

scn3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sodium ion transmembrane transport GO:0035725 21 0.187
Zebrafish Mouse
transmembrane transport GO:0055085 120 0.176
Zebrafish Mouse
larval development GO:0002164 2 0.142
system process GO:0003008 185 0.137
Mouse Rat
regulation of muscle contraction GO:0006937 3 0.109
Mouse
regulation of blood circulation GO:1903522 32 0.103
Mouse
heart morphogenesis GO:0003007 156 0.094
transport GO:0006810 220 0.086
Zebrafish Mouse Rat
embryonic organ development GO:0048568 381 0.084
heart development GO:0007507 313 0.081
ion transmembrane transport GO:0034220 91 0.080
Zebrafish Mouse
establishment of localization GO:0051234 244 0.070
Zebrafish Mouse Rat
single organism localization GO:1902578 225 0.068
Zebrafish Mouse Rat
embryonic heart tube morphogenesis GO:0003143 108 0.064
heart looping GO:0001947 94 0.061
adult behavior GO:0030534 2 0.059
nitrogen compound metabolic process GO:0006807 319 0.059
determination of bilateral symmetry GO:0009855 204 0.058
regulation of biological quality GO:0065008 263 0.057
Mouse
cellular biosynthetic process GO:0044249 286 0.055
multicellular organismal signaling GO:0035637 22 0.054
Mouse
heart process GO:0003015 71 0.054
Mouse
heterocycle metabolic process GO:0046483 290 0.053
regulation of heart contraction GO:0008016 32 0.052
Mouse
positive regulation of biological process GO:0048518 253 0.052
Mouse
ventricular cardiac muscle tissue development GO:0003229 3 0.049
specification of symmetry GO:0009799 204 0.049
aging GO:0007568 2 0.049
actin filament based movement GO:0030048 1 0.048
neurological system process GO:0050877 62 0.047
Rat
cell projection morphogenesis GO:0048858 244 0.047
cardiac muscle cell development GO:0055013 20 0.047
startle response GO:0001964 4 0.046
muscle structure development GO:0061061 196 0.046
cell part morphogenesis GO:0032990 246 0.045
morphogenesis of an epithelium GO:0002009 333 0.045
tube morphogenesis GO:0035239 349 0.044
cardiac muscle tissue development GO:0048738 48 0.044
monovalent inorganic cation transport GO:0015672 42 0.043
Zebrafish Mouse Rat
ion transport GO:0006811 114 0.043
Zebrafish Mouse Rat
organic cyclic compound metabolic process GO:1901360 301 0.043
determination of left right symmetry GO:0007368 179 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.043
neuron differentiation GO:0030182 353 0.042
nucleobase containing compound metabolic process GO:0006139 274 0.041
brain development GO:0007420 293 0.041
circulatory system process GO:0003013 87 0.041
Mouse
positive regulation of transport GO:0051050 2 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
response to light stimulus GO:0009416 46 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.041
regulation of nitrogen compound metabolic process GO:0051171 251 0.041
positive regulation of heart contraction GO:0045823 2 0.040
Mouse
regulation of primary metabolic process GO:0080090 311 0.040
response to chemical GO:0042221 320 0.039
positive regulation of blood circulation GO:1903524 2 0.038
Mouse
heart contraction GO:0060047 71 0.038
Mouse
chemosensory behavior GO:0007635 1 0.037
regulation of metabolic process GO:0019222 359 0.036
synaptic growth at neuromuscular junction GO:0051124 2 0.036
striated muscle tissue development GO:0014706 110 0.036
neuron development GO:0048666 262 0.035
single organism transport GO:0044765 206 0.035
Zebrafish Mouse Rat
embryonic organ morphogenesis GO:0048562 274 0.034
central nervous system development GO:0007417 387 0.034
determination of heart left right asymmetry GO:0061371 117 0.034
regulation of signal transduction GO:0009966 225 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.033
heterocycle biosynthetic process GO:0018130 215 0.033
neurotransmitter transport GO:0006836 2 0.031
striated muscle cell differentiation GO:0051146 129 0.031
regulation of tube size GO:0035150 2 0.030
cell projection organization GO:0030030 284 0.030
neuron projection morphogenesis GO:0048812 161 0.030
response to external stimulus GO:0009605 264 0.030
regulation of system process GO:0044057 40 0.030
Mouse
regulation of multicellular organismal development GO:2000026 223 0.030
muscle cell differentiation GO:0042692 139 0.030
muscle cell development GO:0055001 115 0.030
head development GO:0060322 303 0.029
maintenance of location GO:0051235 4 0.029
neuron neuron synaptic transmission GO:0007270 1 0.029
rna localization GO:0006403 4 0.029
regulation of signaling GO:0023051 235 0.029
cell morphogenesis GO:0000902 289 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
negative regulation of cellular process GO:0048523 283 0.029
positive regulation of cell cycle GO:0045787 3 0.029
gtp catabolic process GO:0006184 2 0.028
neuron projection development GO:0031175 180 0.028
single organism metabolic process GO:0044710 217 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.028
embryonic heart tube development GO:0035050 133 0.027
neurotransmitter secretion GO:0007269 2 0.027
regulation of nucleoside metabolic process GO:0009118 2 0.027
small molecule metabolic process GO:0044281 77 0.027
positive regulation of catabolic process GO:0009896 4 0.027
lipid storage GO:0019915 1 0.027
signal transduction GO:0007165 455 0.026
cognition GO:0050890 1 0.026
regulation of transporter activity GO:0032409 2 0.026
regulation of synapse assembly GO:0051963 3 0.026
striated muscle cell development GO:0055002 108 0.026
cardiac conduction GO:0061337 3 0.026
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.026
regulation of purine nucleotide catabolic process GO:0033121 2 0.026
biosynthetic process GO:0009058 294 0.025
regulation of synapse organization GO:0050807 3 0.025
organic substance biosynthetic process GO:1901576 289 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
cytokinesis GO:0000910 3 0.025
generation of neurons GO:0048699 385 0.024
cellular component morphogenesis GO:0032989 336 0.024
sleep GO:0030431 1 0.024
regulation of gene expression GO:0010468 265 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
axon development GO:0061564 166 0.024
regulation of cell communication GO:0010646 232 0.024
locomotion GO:0040011 313 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
regulation of metal ion transport GO:0010959 4 0.023
inorganic cation transmembrane transport GO:0098662 50 0.023
Zebrafish Mouse
carbon dioxide transport GO:0015670 3 0.023
regulation of actin filament based movement GO:1903115 1 0.023
Mouse
axonogenesis GO:0007409 152 0.023
gene expression GO:0010467 252 0.023
regulation of protein complex assembly GO:0043254 3 0.023
er nucleus signaling pathway GO:0006984 2 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
exocytosis GO:0006887 1 0.022
regulation of transmembrane transporter activity GO:0022898 2 0.022
behavior GO:0007610 74 0.022
regulation of stem cell proliferation GO:0072091 2 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
organelle organization GO:0006996 227 0.022
positive regulation of muscle organ development GO:0048636 1 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
regulation of sequestering of calcium ion GO:0051282 4 0.021
cellular component movement GO:0006928 335 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
response to carbohydrate GO:0009743 3 0.021
meiotic cell cycle process GO:1903046 3 0.021
post embryonic organ development GO:0048569 4 0.021
meiotic nuclear division GO:0007126 4 0.021
cellular component biogenesis GO:0044085 178 0.021
muscle tissue development GO:0060537 110 0.020
regulation of response to stimulus GO:0048583 269 0.020
regulation of sodium ion transport GO:0002028 2 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
regulation of membrane potential GO:0042391 23 0.020
Mouse
lipid catabolic process GO:0016042 4 0.020
regulation of blood vessel size GO:0050880 2 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
actin mediated cell contraction GO:0070252 1 0.020
blood circulation GO:0008015 87 0.020
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.020
regionalization GO:0003002 274 0.020
regulation of binding GO:0051098 3 0.020
organelle assembly GO:0070925 110 0.020
multicellular organism growth GO:0035264 4 0.020
negative regulation of kinase activity GO:0033673 4 0.020
cell cycle g1 s phase transition GO:0044843 1 0.020
single organism organelle organization GO:1902589 199 0.019
regulation of cardiac muscle cell contraction GO:0086004 1 0.019
Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.019
rna metabolic process GO:0016070 219 0.019
organic acid metabolic process GO:0006082 31 0.019
response to topologically incorrect protein GO:0035966 2 0.019
gtp metabolic process GO:0046039 4 0.019
sodium ion transport GO:0006814 24 0.019
Zebrafish Mouse Rat
protein dephosphorylation GO:0006470 3 0.019
amine metabolic process GO:0009308 2 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
cell proliferation involved in heart morphogenesis GO:0061323 2 0.019
membrane repolarization GO:0086009 2 0.019
regulation of membrane repolarization GO:0060306 1 0.018
digestive tract development GO:0048565 265 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
phagocytosis GO:0006909 3 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
amino acid transport GO:0006865 2 0.018
stem cell proliferation GO:0072089 4 0.018
response to alkaloid GO:0043279 2 0.018
cellular component assembly GO:0022607 170 0.018
cellular component disassembly GO:0022411 1 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
regulation of ion transmembrane transporter activity GO:0032412 2 0.018
transmission of nerve impulse GO:0019226 19 0.018
response to stress GO:0006950 263 0.018
regulation of dendrite development GO:0050773 3 0.018
regulation of multicellular organismal process GO:0051239 277 0.017
Mouse
regulation of transcription dna templated GO:0006355 213 0.017
mitochondrion organization GO:0007005 4 0.017
stem cell fate commitment GO:0048865 1 0.017
rna biosynthetic process GO:0032774 181 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
morphogenesis of an epithelial fold GO:0060571 1 0.017
cardiac atrium morphogenesis GO:0003209 2 0.017
neuroblast proliferation GO:0007405 2 0.017
gastrulation GO:0007369 208 0.017
regulation of protein catabolic process GO:0042176 1 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
compound eye development GO:0048749 2 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
somatic muscle development GO:0007525 4 0.017
negative regulation of secretion by cell GO:1903531 2 0.017
sensory organ morphogenesis GO:0090596 200 0.017
regulation of epidermis development GO:0045682 2 0.016
regulation of protein binding GO:0043393 3 0.016
multi organism process GO:0051704 134 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
negative regulation of synapse assembly GO:0051964 2 0.016
atrial ventricular junction remodeling GO:0003294 2 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
regulation of circadian rhythm GO:0042752 4 0.016
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.016
secondary metabolic process GO:0019748 3 0.016
establishment of blood brain barrier GO:0060856 2 0.016
cellular response to external stimulus GO:0071496 2 0.016
regulation of protein transport GO:0051223 3 0.016
small molecule catabolic process GO:0044282 3 0.016
nucleic acid metabolic process GO:0090304 244 0.016
smooth muscle contraction GO:0006939 2 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of reproductive process GO:2000241 4 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
regulation of jak stat cascade GO:0046425 3 0.015
protein import GO:0017038 3 0.015
macromolecular complex disassembly GO:0032984 1 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
regulation of rna metabolic process GO:0051252 224 0.015
negative regulation of signaling GO:0023057 96 0.015
circadian sleep wake cycle process GO:0022410 2 0.015
g protein coupled receptor signaling pathway GO:0007186 74 0.015
axon guidance GO:0007411 86 0.015
angiogenesis GO:0001525 158 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
response to hydrogen peroxide GO:0042542 3 0.015
protein localization to nucleus GO:0034504 3 0.015
positive regulation of neural precursor cell proliferation GO:2000179 1 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
eye development GO:0001654 277 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
tissue remodeling GO:0048771 4 0.015
calcium ion transport into cytosol GO:0060402 3 0.015
regulation of biosynthetic process GO:0009889 250 0.015
negative regulation of metabolic process GO:0009892 86 0.015
hormone secretion GO:0046879 2 0.015
cellular amine metabolic process GO:0044106 2 0.015
hormone transport GO:0009914 2 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
nucleic acid templated transcription GO:0097659 181 0.014
protein complex disassembly GO:0043241 1 0.014
cell death GO:0008219 121 0.014
regulation of cytokine production GO:0001817 3 0.014
cellular response to nutrient levels GO:0031669 2 0.014
response to drug GO:0042493 3 0.014
eye morphogenesis GO:0048592 144 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
protein metabolic process GO:0019538 183 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 1 0.014
cardiac cell development GO:0055006 21 0.014
inorganic ion transmembrane transport GO:0098660 57 0.014
Zebrafish Mouse
blood vessel development GO:0001568 246 0.014
rna transport GO:0050658 2 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
cellular ketone metabolic process GO:0042180 11 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
regulation of gtpase activity GO:0043087 2 0.014
sensory perception of chemical stimulus GO:0007606 3 0.014
cation transmembrane transport GO:0098655 65 0.014
Zebrafish Mouse
cellular response to extracellular stimulus GO:0031668 2 0.014
stem cell division GO:0017145 1 0.014
protein homooligomerization GO:0051260 3 0.013
cell migration GO:0016477 237 0.013
mitotic cytokinesis GO:0000281 3 0.013
regulation of transmembrane transport GO:0034762 18 0.013
Zebrafish Mouse
synaptic vesicle transport GO:0048489 1 0.013
regulation of autophagy GO:0010506 3 0.013
cellular protein catabolic process GO:0044257 4 0.013
cellular response to starvation GO:0009267 1 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
sensory organ development GO:0007423 393 0.013
cellular response to oxygen levels GO:0071453 1 0.013
apoptotic process involved in development GO:1902742 2 0.013
digestive tract morphogenesis GO:0048546 231 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
establishment of rna localization GO:0051236 3 0.013
adherens junction organization GO:0034332 4 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
locomotory behavior GO:0007626 34 0.013
autophagy GO:0006914 4 0.013
sequestering of metal ion GO:0051238 3 0.013
digestive system development GO:0055123 289 0.013
single organism membrane fusion GO:0044801 2 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
phosphorus metabolic process GO:0006793 109 0.013
intracellular mrna localization GO:0008298 1 0.013
metal ion transport GO:0030001 58 0.013
Zebrafish Mouse Rat
cellular response to topologically incorrect protein GO:0035967 2 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
nuclear import GO:0051170 3 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
developmental growth GO:0048589 166 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
vasculature development GO:0001944 278 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
apoptotic process GO:0006915 116 0.012
negative regulation of biological process GO:0048519 304 0.012
cell fate specification GO:0001708 68 0.012
taxis GO:0042330 109 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.012
cardiac muscle cell differentiation GO:0055007 30 0.012
actin filament based process GO:0030029 64 0.012
cortical cytoskeleton organization GO:0030865 1 0.012
spermatid development GO:0007286 2 0.012
phototransduction GO:0007602 2 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
regulation of cell activation GO:0050865 1 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
localization of cell GO:0051674 244 0.012
response to abiotic stimulus GO:0009628 122 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
homeostatic process GO:0042592 142 0.012
Mouse
negative regulation of catabolic process GO:0009895 3 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
protein import into nucleus GO:0006606 3 0.012
camera type eye development GO:0043010 222 0.012
regulation of cardiac muscle contraction GO:0055117 2 0.012
Mouse
protein targeting to membrane GO:0006612 1 0.012
death GO:0016265 121 0.012
membrane fusion GO:0061025 2 0.012
stem cell maintenance GO:0019827 4 0.012
retina development in camera type eye GO:0060041 146 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
synaptic vesicle localization GO:0097479 1 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
sensory perception GO:0007600 39 0.012
Rat
regulation of localization GO:0032879 104 0.012
Zebrafish Mouse
positive regulation of striated muscle tissue development GO:0045844 1 0.012
chordate embryonic development GO:0043009 271 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
double strand break repair GO:0006302 3 0.012
regulation of apoptotic process GO:0042981 98 0.012
sequestering of calcium ion GO:0051208 3 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
centrosome organization GO:0051297 1 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
intracellular signal transduction GO:0035556 85 0.011
protein depolymerization GO:0051261 1 0.011
action potential GO:0001508 19 0.011
Mouse
inner ear development GO:0048839 126 0.011
cation transport GO:0006812 81 0.011
Zebrafish Mouse Rat
regulation of calcium ion transport GO:0051924 2 0.011
glial cell migration GO:0008347 3 0.011
regulation of oocyte development GO:0060281 3 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
carbohydrate homeostasis GO:0033500 1 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
transcription dna templated GO:0006351 181 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
endosomal transport GO:0016197 2 0.011
cytoskeleton organization GO:0007010 96 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
cell cycle g2 m phase transition GO:0044839 4 0.011
muscle organ development GO:0007517 101 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
chemotaxis GO:0006935 104 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
circadian sleep wake cycle GO:0042745 2 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
positive regulation of secretion GO:0051047 1 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
fluid transport GO:0042044 17 0.011
positive regulation of muscle tissue development GO:1901863 1 0.011
cytosolic calcium ion transport GO:0060401 3 0.010
immune system process GO:0002376 241 0.010
negative regulation of signal transduction GO:0009968 94 0.010
organelle fusion GO:0048284 3 0.010
regulation of cell differentiation GO:0045595 142 0.010
pericardium morphogenesis GO:0003344 1 0.010
negative regulation of map kinase activity GO:0043407 2 0.010
response to uv GO:0009411 3 0.010
regulation of circadian sleep wake cycle GO:0042749 1 0.010
regulation of developmental process GO:0050793 247 0.010
muscle fiber development GO:0048747 52 0.010
cellular response to reactive oxygen species GO:0034614 2 0.010
positive regulation of cellular process GO:0048522 201 0.010
nuclear transport GO:0051169 4 0.010
cellular response to radiation GO:0071478 4 0.010
fatty acid catabolic process GO:0009062 1 0.010

scn3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
intrinsic cardiomyopathy DOID:0060036 0 0.027
musculoskeletal system disease DOID:17 0 0.027
heart disease DOID:114 0 0.027
cardiovascular system disease DOID:1287 0 0.027
muscular disease DOID:0080000 0 0.027
cardiomyopathy DOID:0050700 0 0.027
muscle tissue disease DOID:66 0 0.027
hypertrophic cardiomyopathy DOID:11984 0 0.027
myopathy DOID:423 0 0.027
nervous system disease DOID:863 0 0.026
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011