Danio rerio

69 known processes

sec13

SEC13 homolog (S. cerevisiae)

(Aliases: MGC174049,zgc:63980,cb271,sec13l1,wu:fa08f09,MGC63980,sb:cb271)

sec13 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
golgi vesicle transport GO:0048193 3 0.837
Yeast Rat
er to golgi vesicle mediated transport GO:0006888 1 0.778
Yeast Rat
nitrogen compound metabolic process GO:0006807 319 0.523
Yeast
digestive tract development GO:0048565 265 0.393
sulfur compound metabolic process GO:0006790 13 0.335
digestive system development GO:0055123 289 0.290
protein targeting to nucleus GO:0044744 3 0.272
Fly
pancreas development GO:0031016 84 0.267
cellular modified amino acid metabolic process GO:0006575 3 0.265
heparan sulfate proteoglycan metabolic process GO:0030201 6 0.210
hepaticobiliary system development GO:0061008 98 0.205
ribosome assembly GO:0042255 1 0.201
chordate embryonic development GO:0043009 271 0.182
small molecule metabolic process GO:0044281 77 0.182
Yeast
cellular biosynthetic process GO:0044249 286 0.176
Yeast
skeletal system development GO:0001501 181 0.163
single organism biosynthetic process GO:0044711 71 0.151
regulation of embryonic development GO:0045995 47 0.148
localization within membrane GO:0051668 1 0.139
Yeast
single organism transport GO:0044765 206 0.133
single organism intracellular transport GO:1902582 25 0.125
Yeast Rat Fly
larval development GO:0002164 2 0.107
Worm Fly
oxoacid metabolic process GO:0043436 31 0.103
digestive tract morphogenesis GO:0048546 231 0.103
specification of axis polarity GO:0065001 4 0.101
organic acid metabolic process GO:0006082 31 0.098
intracellular transport GO:0046907 32 0.093
Yeast Rat Fly
protein localization to nucleus GO:0034504 3 0.091
Fly
alpha amino acid metabolic process GO:1901605 3 0.086
glycosaminoglycan biosynthetic process GO:0006024 8 0.076
biosynthetic process GO:0009058 294 0.075
Yeast
regulation of protein binding GO:0043393 3 0.074
endocardium formation GO:0060214 1 0.073
organonitrogen compound metabolic process GO:1901564 74 0.072
Yeast
organonitrogen compound biosynthetic process GO:1901566 47 0.071
cellular macromolecule metabolic process GO:0044260 391 0.064
Yeast
protein localization GO:0008104 40 0.058
maturation of ssu rrna GO:0030490 1 0.058
heart development GO:0007507 313 0.057
proteoglycan metabolic process GO:0006029 14 0.055
nucleocytoplasmic transport GO:0006913 4 0.055
Fly
cytokinesis GO:0000910 3 0.055
Worm
chondroitin sulfate proteoglycan metabolic process GO:0050654 8 0.055
nucleobase containing compound biosynthetic process GO:0034654 205 0.054
Yeast
protein import GO:0017038 3 0.054
Fly
vesicle localization GO:0051648 27 0.051
glycoprotein biosynthetic process GO:0009101 21 0.046
determination of left right symmetry GO:0007368 179 0.046
heterocycle metabolic process GO:0046483 290 0.044
Yeast
cellular component morphogenesis GO:0032989 336 0.042
regulation of multicellular organism growth GO:0040014 4 0.040
establishment of protein localization to organelle GO:0072594 4 0.040
Fly
transmembrane transport GO:0055085 120 0.040
protein depolymerization GO:0051261 1 0.039
gene expression GO:0010467 252 0.039
Yeast Fly
glycoprotein metabolic process GO:0009100 23 0.039
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.038
Yeast
erythrocyte development GO:0048821 24 0.037
regulation of cellular amine metabolic process GO:0033238 0 0.036
single organism metabolic process GO:0044710 217 0.036
Yeast
embryonic digestive tract morphogenesis GO:0048557 3 0.036
embryonic cranial skeleton morphogenesis GO:0048701 90 0.035
proximal distal pattern formation GO:0009954 1 0.035
carbohydrate homeostasis GO:0033500 1 0.034
regulation of biological quality GO:0065008 263 0.034
peptide metabolic process GO:0006518 1 0.034
regulation of cytoplasmic transport GO:1903649 4 0.033
extracellular structure organization GO:0043062 27 0.033
establishment of localization in cell GO:0051649 77 0.033
cellular macromolecular complex assembly GO:0034622 24 0.033
regulation of binding GO:0051098 3 0.033
forebrain regionalization GO:0021871 4 0.032
response to stress GO:0006950 263 0.032
gastrulation GO:0007369 208 0.032
embryo development ending in birth or egg hatching GO:0009792 271 0.032
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.031
Yeast
negative regulation of cellular catabolic process GO:0031330 3 0.031
hydrogen peroxide metabolic process GO:0042743 2 0.031
double strand break repair GO:0006302 3 0.031
myeloid cell development GO:0061515 32 0.029
pronuclear migration GO:0035046 1 0.029
response to chemical GO:0042221 320 0.029
single organism membrane organization GO:0044802 20 0.029
Yeast
nuclear import GO:0051170 3 0.028
Fly
response to other organism GO:0051707 97 0.028
aminoglycan biosynthetic process GO:0006023 8 0.027
transport GO:0006810 220 0.027
autophagy GO:0006914 4 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.027
Yeast
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.026
response to external biotic stimulus GO:0043207 97 0.026
carbohydrate derivative metabolic process GO:1901135 61 0.026
Yeast
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
Yeast
carboxylic acid metabolic process GO:0019752 22 0.026
epithelial cell morphogenesis GO:0003382 2 0.025
inner ear development GO:0048839 126 0.025
ectodermal placode development GO:0071696 37 0.025
organelle assembly GO:0070925 110 0.025
cell surface receptor signaling pathway GO:0007166 325 0.025
Fly
neural tube patterning GO:0021532 33 0.025
embryonic neurocranium morphogenesis GO:0048702 15 0.024
negative regulation of catabolic process GO:0009895 3 0.024
mitotic g2 dna damage checkpoint GO:0007095 3 0.024
embryonic skeletal system morphogenesis GO:0048704 93 0.024
neuroblast fate commitment GO:0014017 1 0.024
nucleoside monophosphate catabolic process GO:0009125 4 0.024
multicellular organism growth GO:0035264 4 0.023
gland development GO:0048732 143 0.023
protein import into nucleus GO:0006606 3 0.023
Fly
exocrine pancreas development GO:0031017 28 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
Worm
amine metabolic process GO:0009308 2 0.022
response to biotic stimulus GO:0009607 97 0.022
ribonucleoside monophosphate catabolic process GO:0009158 4 0.022
response to antibiotic GO:0046677 1 0.021
regulation of cell proliferation involved in tissue homeostasis GO:0060784 2 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.020
Yeast
reflex GO:0060004 2 0.020
olfactory placode development GO:0071698 12 0.020
cellular amino acid metabolic process GO:0006520 7 0.019
protein targeting to membrane GO:0006612 1 0.019
pyruvate metabolic process GO:0006090 1 0.019
regulation of autophagy GO:0010506 3 0.019
cellular amide metabolic process GO:0043603 4 0.019
mucopolysaccharide metabolic process GO:1903510 2 0.018
cell part morphogenesis GO:0032990 246 0.018
central nervous system development GO:0007417 387 0.018
mitotic cell cycle GO:0000278 64 0.018
Worm
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.018
glycosaminoglycan metabolic process GO:0030203 9 0.018
carbohydrate derivative biosynthetic process GO:1901137 43 0.018
dicarboxylic acid transport GO:0006835 1 0.017
g2 dna damage checkpoint GO:0031572 3 0.017
optic placode formation involved in camera type eye formation GO:0046619 3 0.017
midbrain development GO:0030901 28 0.017
specification of symmetry GO:0009799 204 0.017
embryonic skeletal system development GO:0048706 97 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
Yeast
regulation of establishment of protein localization GO:0070201 4 0.016
gene silencing by rna GO:0031047 4 0.016
peptide transport GO:0015833 1 0.016
regulation of growth rate GO:0040009 1 0.016
mitotic dna damage checkpoint GO:0044773 4 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
posttranscriptional gene silencing by rna GO:0035194 3 0.016
dorsal ventral neural tube patterning GO:0021904 1 0.016
glucose homeostasis GO:0042593 1 0.016
maintenance of location GO:0051235 4 0.016
interspecies interaction between organisms GO:0044419 4 0.015
negative regulation of metabolic process GO:0009892 86 0.015
Fly
nucleic acid metabolic process GO:0090304 244 0.015
Yeast
hormone secretion GO:0046879 2 0.015
lateral line development GO:0048882 66 0.015
embryonic organ development GO:0048568 381 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
sensory system development GO:0048880 76 0.015
embryonic digestive tract development GO:0048566 4 0.014
regulation of organelle assembly GO:1902115 4 0.014
single organism cellular localization GO:1902580 46 0.014
Yeast Fly
carbohydrate metabolic process GO:0005975 12 0.014
nuclear transport GO:0051169 4 0.014
Fly
extracellular matrix assembly GO:0085029 1 0.014
regulation of cell projection assembly GO:0060491 4 0.014
forebrain anterior posterior pattern specification GO:0021797 3 0.014
spindle assembly involved in meiosis GO:0090306 1 0.014
actin filament polymerization GO:0030041 2 0.014
regulation of cell shape GO:0008360 1 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
chromosome organization involved in meiosis GO:0070192 1 0.013
golgi organization GO:0007030 1 0.013
type b pancreatic cell development GO:0003323 4 0.013
membrane hyperpolarization GO:0060081 1 0.013
regulation of endothelial cell differentiation GO:0045601 3 0.013
organic substance biosynthetic process GO:1901576 289 0.013
Yeast
positive regulation of transport GO:0051050 2 0.013
eye photoreceptor cell differentiation GO:0001754 45 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
Yeast
centrosome organization GO:0051297 1 0.013
ribonucleoprotein complex assembly GO:0022618 5 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
mitotic dna integrity checkpoint GO:0044774 4 0.013
cellular ketone metabolic process GO:0042180 11 0.012
receptor mediated endocytosis GO:0006898 6 0.012
Worm
cellular component movement GO:0006928 335 0.012
histone deacetylation GO:0016575 2 0.012
reactive oxygen species metabolic process GO:0072593 6 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
nuclear export GO:0051168 1 0.012
regulation of fatty acid beta oxidation GO:0031998 1 0.012
regulation of oligodendrocyte differentiation GO:0048713 1 0.012
endomembrane system organization GO:0010256 13 0.012
chondrocyte development GO:0002063 4 0.012
regulation of heart growth GO:0060420 2 0.012
apoptotic process GO:0006915 116 0.012
Worm
regulation of developmental process GO:0050793 247 0.012
cell proliferation in dorsal spinal cord GO:0010456 2 0.012
vesicle mediated transport GO:0016192 22 0.012
Yeast Rat Worm
retinal pigment epithelium development GO:0003406 8 0.012
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 7 0.012
single organism nuclear import GO:1902593 3 0.012
Fly
protein polymerization GO:0051258 4 0.012
embryonic viscerocranium morphogenesis GO:0048703 52 0.012
dna biosynthetic process GO:0071897 3 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
regulation of protein transport GO:0051223 3 0.011
atp catabolic process GO:0006200 4 0.011
membrane organization GO:0061024 21 0.011
Yeast
regulation of protein processing GO:0070613 10 0.011
positive regulation of oocyte development GO:0060282 1 0.011
single organism localization GO:1902578 225 0.011
regulation of protein complex assembly GO:0043254 3 0.011
membrane invagination GO:0010324 1 0.011
spindle assembly involved in mitosis GO:0090307 1 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
pyrimidine containing compound metabolic process GO:0072527 3 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
interaction with host GO:0051701 4 0.011
enteroendocrine cell differentiation GO:0035883 9 0.011
protein complex disassembly GO:0043241 1 0.011
liver development GO:0001889 96 0.011
neuron projection development GO:0031175 180 0.010
cellular response to light stimulus GO:0071482 4 0.010
regulation of protein depolymerization GO:1901879 1 0.010
neural retina development GO:0003407 49 0.010
cellular amine metabolic process GO:0044106 2 0.010
protein acylation GO:0043543 3 0.010
heme metabolic process GO:0042168 9 0.010
er nucleus signaling pathway GO:0006984 2 0.010
erythrocyte differentiation GO:0030218 54 0.010
organic substance transport GO:0071702 58 0.010
establishment of localization GO:0051234 244 0.010

sec13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
endocrine gland cancer DOID:170 0 0.038
cancer DOID:162 0 0.038
disease of cellular proliferation DOID:14566 0 0.038
organ system cancer DOID:0050686 0 0.038
disease of anatomical entity DOID:7 0 0.032
disease of metabolism DOID:0014667 0 0.024
inherited metabolic disorder DOID:655 0 0.024
diabetes mellitus DOID:9351 0 0.022
type 2 diabetes mellitus DOID:9352 0 0.022
carbohydrate metabolism disease DOID:0050013 0 0.022
glucose metabolism disease DOID:4194 0 0.022
acquired metabolic disease DOID:0060158 0 0.022
large intestine cancer DOID:5672 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
intestinal cancer DOID:10155 0 0.011
physical disorder DOID:0080015 0 0.010