Danio rerio

0 known processes

sec61al2

Sec61 alpha like 2

(Aliases: wu:fi26f11,cb413,wu:fb36f12,wu:fb36f05,wu:fb37d04,sec61b)

sec61al2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein targeting to membrane GO:0006612 1 0.281
Human Yeast
lipid storage GO:0019915 1 0.241
maintenance of location GO:0051235 4 0.205
cellular biosynthetic process GO:0044249 286 0.142
cellular response to unfolded protein GO:0034620 2 0.109
regulation of biological quality GO:0065008 263 0.108
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.107
Yeast
larval development GO:0002164 2 0.102
establishment of localization in cell GO:0051649 77 0.096
Human Yeast
organic substance biosynthetic process GO:1901576 289 0.092
cellular response to topologically incorrect protein GO:0035967 2 0.089
biosynthetic process GO:0009058 294 0.088
proteasomal protein catabolic process GO:0010498 2 0.086
Yeast
macromolecule biosynthetic process GO:0009059 227 0.080
transport GO:0006810 220 0.079
Human Yeast Fly
striated muscle cell differentiation GO:0051146 129 0.079
regulation of metabolic process GO:0019222 359 0.077
Fly
cellular protein catabolic process GO:0044257 4 0.075
Yeast
cellular catabolic process GO:0044248 27 0.067
Yeast Fly
endoplasmic reticulum unfolded protein response GO:0030968 2 0.067
response to chemical GO:0042221 320 0.067
positive regulation of transport GO:0051050 2 0.062
Fly
regulation of cellular metabolic process GO:0031323 320 0.061
Fly
chemical homeostasis GO:0048878 49 0.057
regulation of nitrogen compound metabolic process GO:0051171 251 0.057
response to stress GO:0006950 263 0.056
regulation of multicellular organismal process GO:0051239 277 0.056
cellular macromolecule metabolic process GO:0044260 391 0.056
Yeast
modification dependent protein catabolic process GO:0019941 3 0.056
Yeast
regulation of macromolecule metabolic process GO:0060255 317 0.053
hormone transport GO:0009914 2 0.052
golgi vesicle transport GO:0048193 3 0.052
positive regulation of secretion by cell GO:1903532 1 0.050
response to organic substance GO:0010033 153 0.049
negative regulation of autophagy GO:0010507 1 0.048
Fly
establishment of localization GO:0051234 244 0.048
Human Yeast Fly
multicellular organism growth GO:0035264 4 0.046
cellular response to starvation GO:0009267 1 0.045
cellular response to organic substance GO:0071310 105 0.045
transition metal ion transport GO:0000041 6 0.044
Fly
negative regulation of cellular catabolic process GO:0031330 3 0.042
Fly
response to topologically incorrect protein GO:0035966 2 0.041
embryonic heart tube morphogenesis GO:0003143 108 0.041
regulation of nucleic acid templated transcription GO:1903506 213 0.040
aging GO:0007568 2 0.039
cellular nitrogen compound metabolic process GO:0034641 290 0.039
cellular response to nutrient levels GO:0031669 2 0.039
organelle organization GO:0006996 227 0.038
Human
ubiquitin dependent protein catabolic process GO:0006511 3 0.037
Yeast
skeletal system morphogenesis GO:0048705 102 0.036
embryo development ending in birth or egg hatching GO:0009792 271 0.036
Worm Fly
apoptotic process GO:0006915 116 0.035
Worm
homeostatic process GO:0042592 142 0.035
single organism transport GO:0044765 206 0.033
Human Yeast Fly
anatomical structure arrangement GO:0048532 2 0.032
response to unfolded protein GO:0006986 2 0.032
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
positive regulation of translation GO:0045727 1 0.030
regulation of multicellular organism growth GO:0040014 4 0.030
regulation of primary metabolic process GO:0080090 311 0.030
regulation of blood vessel size GO:0050880 2 0.029
cellular macromolecule biosynthetic process GO:0034645 224 0.029
cellular modified amino acid metabolic process GO:0006575 3 0.028
cellular response to stress GO:0033554 62 0.028
autophagy GO:0006914 4 0.028
Fly
skeletal system development GO:0001501 181 0.027
gastrulation GO:0007369 208 0.027
positive regulation of biological process GO:0048518 253 0.027
Fly
interaction with host GO:0051701 4 0.027
Fly
response to corticosteroid GO:0031960 1 0.027
negative regulation of mapk cascade GO:0043409 4 0.026
chordate embryonic development GO:0043009 271 0.025
regulation of cellular biosynthetic process GO:0031326 245 0.025
gtp metabolic process GO:0046039 4 0.025
regulation of hormone secretion GO:0046883 2 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
regulation of organ growth GO:0046620 3 0.024
positive regulation of secretion GO:0051047 1 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
cellular response to lipid GO:0071396 39 0.024
signal transduction GO:0007165 455 0.023
response to glucocorticoid GO:0051384 1 0.023
response to endoplasmic reticulum stress GO:0034976 6 0.023
cellular response to steroid hormone stimulus GO:0071383 31 0.023
regulation of localization GO:0032879 104 0.023
Fly
regulation of biomineral tissue development GO:0070167 2 0.023
cellular response to chemical stimulus GO:0070887 157 0.023
embryonic organ morphogenesis GO:0048562 274 0.022
water homeostasis GO:0030104 4 0.022
tube closure GO:0060606 1 0.022
regulation of cell communication GO:0010646 232 0.022
cellular response to endogenous stimulus GO:0071495 68 0.022
cellular component assembly GO:0022607 170 0.021
response to endogenous stimulus GO:0009719 83 0.021
cellular protein metabolic process GO:0044267 129 0.021
Yeast
hormone secretion GO:0046879 2 0.021
metal ion homeostasis GO:0055065 26 0.021
positive regulation of apoptotic signaling pathway GO:2001235 1 0.021
er nucleus signaling pathway GO:0006984 2 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
Yeast
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
heart looping GO:0001947 94 0.020
gene expression GO:0010467 252 0.019
response to steroid hormone GO:0048545 35 0.019
regulation of developmental process GO:0050793 247 0.019
iron ion transmembrane transport GO:0034755 3 0.019
Fly
protein n linked glycosylation GO:0006487 1 0.019
single organism organelle organization GO:1902589 199 0.019
regionalization GO:0003002 274 0.018
erk1 and erk2 cascade GO:0070371 4 0.018
cellular amide metabolic process GO:0043603 4 0.018
phototransduction GO:0007602 2 0.018
embryonic skeletal system development GO:0048706 97 0.018
regulation of gtpase activity GO:0043087 2 0.018
negative regulation of protein kinase activity GO:0006469 4 0.017
transmembrane transport GO:0055085 120 0.017
Yeast Fly
locomotion GO:0040011 313 0.017
Fly
digestive tract morphogenesis GO:0048546 231 0.017
primary neural tube formation GO:0014020 1 0.017
regulation of gene expression GO:0010468 265 0.017
heart development GO:0007507 313 0.016
mesenchyme development GO:0060485 127 0.016
protein metabolic process GO:0019538 183 0.016
Yeast
intracellular signal transduction GO:0035556 85 0.016
regulation of bone mineralization GO:0030500 2 0.016
negative regulation of metabolic process GO:0009892 86 0.016
Fly
muscle structure development GO:0061061 196 0.016
regulation of neurotransmitter secretion GO:0046928 1 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
single organism metabolic process GO:0044710 217 0.016
macromolecule glycosylation GO:0043413 9 0.015
regulation of tube size GO:0035150 2 0.015
negative regulation of chromosome organization GO:2001251 1 0.015
tube morphogenesis GO:0035239 349 0.015
response to organic cyclic compound GO:0014070 51 0.015
response to estrogen GO:0043627 27 0.015
positive regulation of cellular process GO:0048522 201 0.015
Fly
negative regulation of heart contraction GO:0045822 2 0.015
negative regulation of kinase activity GO:0033673 4 0.015
single organism localization GO:1902578 225 0.015
Human Yeast Fly
lipid localization GO:0010876 11 0.015
hepatocyte proliferation GO:0072574 2 0.015
golgi organization GO:0007030 1 0.015
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.014
calcium mediated signaling GO:0019722 2 0.014
response to external biotic stimulus GO:0043207 97 0.014
Fly
regulation of biosynthetic process GO:0009889 250 0.014
digestive system development GO:0055123 289 0.014
female gonad development GO:0008585 4 0.014
negative regulation of blood circulation GO:1903523 2 0.014
peptide metabolic process GO:0006518 1 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.013
circulatory system process GO:0003013 87 0.013
brain development GO:0007420 293 0.013
Zebrafish
organic substance catabolic process GO:1901575 28 0.013
Yeast
regulation of cell activation GO:0050865 1 0.013
response to biotic stimulus GO:0009607 97 0.013
Fly
growth GO:0040007 174 0.013
Human
positive regulation of cytoskeleton organization GO:0051495 3 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
regulation of translation GO:0006417 3 0.013
response to lipid GO:0033993 60 0.013
cellular component biogenesis GO:0044085 178 0.013
translation GO:0006412 5 0.012
cellular response to external stimulus GO:0071496 2 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
regulation of rna metabolic process GO:0051252 224 0.012
system process GO:0003008 185 0.012
establishment of organelle localization GO:0051656 45 0.012
cell migration GO:0016477 237 0.012
neural crest cell development GO:0014032 62 0.012
vesicle mediated transport GO:0016192 22 0.012
carbohydrate homeostasis GO:0033500 1 0.012
phosphatidylinositol mediated signaling GO:0048015 2 0.012
carboxylic acid metabolic process GO:0019752 22 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of mrna processing GO:0050684 3 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
organelle localization GO:0051640 49 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
cell substrate junction assembly GO:0007044 2 0.011
regulation of signal transduction GO:0009966 225 0.011
cellular response to hormone stimulus GO:0032870 39 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
regulation of immunoglobulin production GO:0002637 1 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
translational initiation GO:0006413 3 0.010
positive regulation of glucose transport GO:0010828 1 0.010

sec61al2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.104
disease of metabolism DOID:0014667 0 0.104
disease of anatomical entity DOID:7 0 0.087
integumentary system disease DOID:16 0 0.019
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
nervous system disease DOID:863 0 0.011