Danio rerio

0 known processes

sec61b

Sec61 beta subunit

(Aliases: zgc:92922,MGC191409,fa20b05,wu:fa20b05,MGC92922)

sec61b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heterocycle metabolic process GO:0046483 290 0.181
lipid storage GO:0019915 1 0.173
regulation of transcription dna templated GO:0006355 213 0.160
regulation of cell projection assembly GO:0060491 4 0.139
regulation of biological quality GO:0065008 263 0.137
maintenance of location GO:0051235 4 0.127
positive regulation of cellular component biogenesis GO:0044089 3 0.125
axon development GO:0061564 166 0.125
cellular macromolecule metabolic process GO:0044260 391 0.124
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.122
regulation of cellular metabolic process GO:0031323 320 0.115
larval development GO:0002164 2 0.113
generation of neurons GO:0048699 385 0.112
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.110
regulation of multicellular organismal process GO:0051239 277 0.098
cell surface receptor signaling pathway GO:0007166 325 0.094
regulation of biosynthetic process GO:0009889 250 0.094
signal transduction GO:0007165 455 0.093
response to external stimulus GO:0009605 264 0.086
nitrogen compound metabolic process GO:0006807 319 0.083
cellular protein catabolic process GO:0044257 4 0.082
cellular nitrogen compound metabolic process GO:0034641 290 0.079
organic cyclic compound metabolic process GO:1901360 301 0.077
positive regulation of cellular process GO:0048522 201 0.077
embryo development ending in birth or egg hatching GO:0009792 271 0.076
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.074
positive regulation of muscle cell differentiation GO:0051149 1 0.074
regulation of reproductive process GO:2000241 4 0.072
regulation of nucleic acid templated transcription GO:1903506 213 0.072
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.071
cellular modified amino acid metabolic process GO:0006575 3 0.070
regulation of signaling GO:0023051 235 0.069
single organism transport GO:0044765 206 0.068
establishment of protein localization to organelle GO:0072594 4 0.066
positive regulation of metabolic process GO:0009893 108 0.065
response to chemical GO:0042221 320 0.064
regulation of protein complex assembly GO:0043254 3 0.064
cellular aromatic compound metabolic process GO:0006725 295 0.064
central nervous system development GO:0007417 387 0.062
nucleobase containing compound metabolic process GO:0006139 274 0.062
embryonic organ development GO:0048568 381 0.061
protein import into nucleus GO:0006606 3 0.058
modification dependent protein catabolic process GO:0019941 3 0.058
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.058
regulation of macromolecule metabolic process GO:0060255 317 0.057
modification dependent macromolecule catabolic process GO:0043632 3 0.056
regulation of cell communication GO:0010646 232 0.055
regulation of filopodium assembly GO:0051489 2 0.053
nuclear transport GO:0051169 4 0.052
nucleic acid metabolic process GO:0090304 244 0.052
negative regulation of cellular process GO:0048523 283 0.051
regulation of rna metabolic process GO:0051252 224 0.051
reflex GO:0060004 2 0.050
neuron development GO:0048666 262 0.050
positive regulation of transport GO:0051050 2 0.050
ameboidal type cell migration GO:0001667 143 0.049
cell morphogenesis GO:0000902 289 0.049
adult behavior GO:0030534 2 0.047
rna metabolic process GO:0016070 219 0.047
cellular biosynthetic process GO:0044249 286 0.047
multi organism process GO:0051704 134 0.047
ubiquitin dependent protein catabolic process GO:0006511 3 0.047
regulation of response to stimulus GO:0048583 269 0.047
regulation of nitrogen compound metabolic process GO:0051171 251 0.045
protein import GO:0017038 3 0.044
establishment of localization GO:0051234 244 0.044
phagocytosis GO:0006909 3 0.044
heterocycle biosynthetic process GO:0018130 215 0.044
system process GO:0003008 185 0.043
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
protein targeting to nucleus GO:0044744 3 0.043
growth GO:0040007 174 0.043
positive regulation of protein complex assembly GO:0031334 2 0.042
nucleocytoplasmic transport GO:0006913 4 0.042
gtp metabolic process GO:0046039 4 0.041
regulation of nervous system development GO:0051960 90 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.041
organic substance biosynthetic process GO:1901576 289 0.041
axonogenesis GO:0007409 152 0.041
response to abiotic stimulus GO:0009628 122 0.041
positive regulation of cellular catabolic process GO:0031331 3 0.041
cellular localization GO:0051641 97 0.040
positive regulation of cellular biosynthetic process GO:0031328 68 0.040
actin polymerization or depolymerization GO:0008154 2 0.040
establishment of localization in cell GO:0051649 77 0.040
cellular component morphogenesis GO:0032989 336 0.039
regulation of intracellular protein transport GO:0033157 3 0.039
proteasomal protein catabolic process GO:0010498 2 0.039
regulation of nucleotide catabolic process GO:0030811 2 0.039
single organism localization GO:1902578 225 0.038
positive regulation of biological process GO:0048518 253 0.038
regulation of protein catabolic process GO:0042176 1 0.038
cell projection organization GO:0030030 284 0.038
positive regulation of macromolecule metabolic process GO:0010604 93 0.038
cell migration GO:0016477 237 0.038
organelle organization GO:0006996 227 0.037
positive regulation of catabolic process GO:0009896 4 0.037
cellular macromolecule biosynthetic process GO:0034645 224 0.037
angiogenesis GO:0001525 158 0.037
aromatic compound biosynthetic process GO:0019438 217 0.036
aging GO:0007568 2 0.036
regulation of cell morphogenesis GO:0022604 42 0.035
protein localization to nucleus GO:0034504 3 0.034
regulation of gene expression GO:0010468 265 0.034
neuron differentiation GO:0030182 353 0.033
nuclear import GO:0051170 3 0.033
rna localization GO:0006403 4 0.033
transcription dna templated GO:0006351 181 0.033
macromolecule biosynthetic process GO:0009059 227 0.033
chordate embryonic development GO:0043009 271 0.033
regulation of primary metabolic process GO:0080090 311 0.032
biosynthetic process GO:0009058 294 0.032
positive regulation of cytoskeleton organization GO:0051495 3 0.032
single organism metabolic process GO:0044710 217 0.032
myeloid cell differentiation GO:0030099 86 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.032
regulation of metabolic process GO:0019222 359 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.032
golgi vesicle transport GO:0048193 3 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
negative regulation of catabolic process GO:0009895 3 0.031
sensory organ development GO:0007423 393 0.030
gene expression GO:0010467 252 0.030
neuron projection morphogenesis GO:0048812 161 0.030
positive regulation of reproductive process GO:2000243 2 0.030
meiotic nuclear division GO:0007126 4 0.030
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
vasculature development GO:0001944 278 0.030
regulation of cellular component organization GO:0051128 86 0.030
developmental growth GO:0048589 166 0.030
cell part morphogenesis GO:0032990 246 0.030
cell morphogenesis involved in differentiation GO:0000904 195 0.030
er to golgi vesicle mediated transport GO:0006888 1 0.029
regulation of cellular biosynthetic process GO:0031326 245 0.029
regulation of gtpase activity GO:0043087 2 0.029
cell motility GO:0048870 244 0.029
cell growth GO:0016049 57 0.028
protein stabilization GO:0050821 2 0.028
muscle structure development GO:0061061 196 0.028
positive regulation of gene expression GO:0010628 71 0.028
protein polymerization GO:0051258 4 0.028
autophagy GO:0006914 4 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.028
synaptic growth at neuromuscular junction GO:0051124 2 0.028
cellular response to organic substance GO:0071310 105 0.028
guanosine containing compound catabolic process GO:1901069 2 0.028
neurological system process GO:0050877 62 0.027
regulation of synapse assembly GO:0051963 3 0.027
positive regulation of cell cycle GO:0045787 3 0.027
cellular component biogenesis GO:0044085 178 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
embryonic organ morphogenesis GO:0048562 274 0.026
regulation of cell differentiation GO:0045595 142 0.026
sensory organ morphogenesis GO:0090596 200 0.026
cognition GO:0050890 1 0.026
regulation of protein transport GO:0051223 3 0.026
negative regulation of response to stimulus GO:0048585 104 0.025
locomotion GO:0040011 313 0.025
regulation of developmental process GO:0050793 247 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
blood vessel morphogenesis GO:0048514 216 0.024
head development GO:0060322 303 0.024
positive regulation of cellular metabolic process GO:0031325 94 0.024
protein complex subunit organization GO:0071822 46 0.024
nucleic acid templated transcription GO:0097659 181 0.024
regulation of synapse organization GO:0050807 3 0.024
regulation of cell development GO:0060284 100 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.024
multicellular organismal metabolic process GO:0044236 2 0.024
response to organic substance GO:0010033 153 0.023
regulation of rna biosynthetic process GO:2001141 213 0.023
regulation of sarcomere organization GO:0060297 2 0.023
multi organism cellular process GO:0044764 2 0.023
regulation of meiotic cell cycle GO:0051445 1 0.023
neuromuscular process controlling balance GO:0050885 3 0.023
negative regulation of signaling GO:0023057 96 0.023
response to stress GO:0006950 263 0.023
negative regulation of cellular metabolic process GO:0031324 77 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
convergent extension GO:0060026 118 0.022
positive regulation of nucleic acid templated transcription GO:1903508 57 0.022
peptidyl threonine phosphorylation GO:0018107 1 0.022
regulation of signal transduction GO:0009966 225 0.022
digestive system development GO:0055123 289 0.022
forebrain development GO:0030900 96 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
cell projection morphogenesis GO:0048858 244 0.022
stem cell proliferation GO:0072089 4 0.022
transport GO:0006810 220 0.022
eye development GO:0001654 277 0.022
immune system process GO:0002376 241 0.021
rna biosynthetic process GO:0032774 181 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
cellular component movement GO:0006928 335 0.021
regulation of cell activation GO:0050865 1 0.021
peptidyl serine modification GO:0018209 2 0.021
regulation of binding GO:0051098 3 0.020
brain development GO:0007420 293 0.020
hemopoiesis GO:0030097 183 0.020
gastrulation GO:0007369 208 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.020
single organism organelle organization GO:1902589 199 0.020
regulation of stem cell differentiation GO:2000736 4 0.019
mesenchyme development GO:0060485 127 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
cell death GO:0008219 121 0.019
death GO:0016265 121 0.019
response to other organism GO:0051707 97 0.019
response to external biotic stimulus GO:0043207 97 0.018
specification of symmetry GO:0009799 204 0.018
regulation of dendrite morphogenesis GO:0048814 3 0.018
multicellular organism growth GO:0035264 4 0.018
sexual reproduction GO:0019953 36 0.018
cell cell signaling GO:0007267 52 0.018
muscle cell differentiation GO:0042692 139 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
gtp catabolic process GO:0006184 2 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
immune system development GO:0002520 191 0.018
stem cell maintenance GO:0019827 4 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
single organism nuclear import GO:1902593 3 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
negative regulation of signal transduction GO:0009968 94 0.017
small molecule metabolic process GO:0044281 77 0.017
regulation of localization GO:0032879 104 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
regulation of organelle assembly GO:1902115 4 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
localization of cell GO:0051674 244 0.016
protein metabolic process GO:0019538 183 0.016
heart morphogenesis GO:0003007 156 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
blood vessel development GO:0001568 246 0.016
determination of bilateral symmetry GO:0009855 204 0.016
mononuclear cell proliferation GO:0032943 1 0.016
regulation of metal ion transport GO:0010959 4 0.016
collagen metabolic process GO:0032963 2 0.016
negative regulation of developmental process GO:0051093 65 0.016
programmed cell death GO:0012501 119 0.016
regulation of protein polymerization GO:0032271 2 0.016
regulation of multicellular organismal development GO:2000026 223 0.015
fertilization GO:0009566 3 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
stem cell development GO:0048864 82 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
positive regulation of multi organism process GO:0043902 3 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
meiotic cell cycle process GO:1903046 3 0.015
mesoderm development GO:0007498 88 0.015
oxoacid metabolic process GO:0043436 31 0.015
phosphorylation GO:0016310 69 0.015
hormone transport GO:0009914 2 0.015
hard palate development GO:0060022 4 0.015
regulation of apoptotic process GO:0042981 98 0.015
cellular protein metabolic process GO:0044267 129 0.015
regulation of cytokine production GO:0001817 3 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
positive regulation of biosynthetic process GO:0009891 68 0.014
regulation of neurogenesis GO:0050767 87 0.014
negative regulation of metabolic process GO:0009892 86 0.014
response to biotic stimulus GO:0009607 97 0.014
chemosensory behavior GO:0007635 1 0.014
macromolecule modification GO:0043412 111 0.014
positive regulation of transcription dna templated GO:0045893 57 0.014
regulation of dna replication GO:0006275 3 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
negative regulation of synapse assembly GO:0051964 2 0.013
positive regulation of secretion GO:0051047 1 0.013
viral process GO:0016032 1 0.013
synaptic transmission GO:0007268 35 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
positive regulation of rna biosynthetic process GO:1902680 57 0.013
response to growth factor GO:0070848 39 0.013
single organism intracellular transport GO:1902582 25 0.013
gland development GO:0048732 143 0.013
interspecies interaction between organisms GO:0044419 4 0.013
regulation of calcium ion transport GO:0051924 2 0.013
embryonic hemopoiesis GO:0035162 53 0.013
macromolecule localization GO:0033036 54 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
cellular lipid catabolic process GO:0044242 3 0.013
sprouting angiogenesis GO:0002040 53 0.013
regulation of cell death GO:0010941 103 0.013
behavior GO:0007610 74 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
regulation of oocyte development GO:0060281 3 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
lateral inhibition GO:0046331 1 0.012
regulation of programmed cell death GO:0043067 101 0.012
organic acid metabolic process GO:0006082 31 0.012
cellular component assembly GO:0022607 170 0.012
fatty acid catabolic process GO:0009062 1 0.012
wnt signaling pathway GO:0016055 80 0.012
fatty acid beta oxidation GO:0006635 1 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
positive regulation of cell activation GO:0050867 1 0.012
homeostatic process GO:0042592 142 0.012
apoptotic process GO:0006915 116 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
regulation of blood vessel size GO:0050880 2 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
regulation of organelle organization GO:0033043 29 0.012
g protein coupled receptor signaling pathway GO:0007186 74 0.012
camera type eye development GO:0043010 222 0.012
actin filament polymerization GO:0030041 2 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
cellular response to growth factor stimulus GO:0071363 39 0.011
nucleic acid transport GO:0050657 2 0.011
negative regulation of defense response GO:0031348 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
cell projection assembly GO:0030031 64 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
negative regulation of biological process GO:0048519 304 0.011
intracellular signal transduction GO:0035556 85 0.011
cell cycle arrest GO:0007050 1 0.011
tube morphogenesis GO:0035239 349 0.011
catenin import into nucleus GO:0035411 2 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
b cell activation GO:0042113 2 0.011
response to endogenous stimulus GO:0009719 83 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
positive regulation of rna metabolic process GO:0051254 59 0.011
blood vessel endothelial cell migration GO:0043534 18 0.011
negative regulation of gene expression GO:0010629 65 0.011
adherens junction organization GO:0034332 4 0.011
regulation of neuron projection development GO:0010975 40 0.011
protein modification process GO:0036211 100 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
regulation of chromosome segregation GO:0051983 1 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
muscle organ development GO:0007517 101 0.010
positive regulation of signaling GO:0023056 56 0.010
digestive tract development GO:0048565 265 0.010
hormone secretion GO:0046879 2 0.010
skeletal system morphogenesis GO:0048705 102 0.010
cellular macromolecular complex assembly GO:0034622 24 0.010
cellular ketone metabolic process GO:0042180 11 0.010
regulation of epithelial to mesenchymal transition GO:0010717 3 0.010
inositol lipid mediated signaling GO:0048017 2 0.010
regulation of growth GO:0040008 42 0.010
intracellular transport GO:0046907 32 0.010
regulation of hormone secretion GO:0046883 2 0.010
organic substance transport GO:0071702 58 0.010

sec61b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
organ system cancer DOID:0050686 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
cancer DOID:162 0 0.030
inherited metabolic disorder DOID:655 0 0.017
disease of metabolism DOID:0014667 0 0.017
nervous system disease DOID:863 0 0.015