Danio rerio

20 known processes

serpinc1

serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1

(Aliases: zgc:92299,wu:fb18f10,MGC92299)

serpinc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue remodeling GO:0048771 4 0.168
response to hormone GO:0009725 48 0.112
cellular response to estrogen stimulus GO:0071391 24 0.112
response to steroid hormone GO:0048545 35 0.102
cellular macromolecule metabolic process GO:0044260 391 0.058
activation of mapk activity GO:0000187 3 0.057
regulation of developmental process GO:0050793 247 0.054
regulation of primary metabolic process GO:0080090 311 0.053
Rat Fly
response to glucose GO:0009749 3 0.053
negative regulation of cellular process GO:0048523 283 0.053
Rat Fly
taurine metabolic process GO:0019530 1 0.051
regulation of cellular metabolic process GO:0031323 320 0.050
Rat Fly
multicellular organismal metabolic process GO:0044236 2 0.050
cellular nitrogen compound metabolic process GO:0034641 290 0.048
gene expression GO:0010467 252 0.047
regulation of nitrogen compound metabolic process GO:0051171 251 0.046
cellular amine metabolic process GO:0044106 2 0.046
regulation of cell differentiation GO:0045595 142 0.042
alcohol biosynthetic process GO:0046165 2 0.042
meiotic nuclear division GO:0007126 4 0.041
regulation of metabolic process GO:0019222 359 0.040
Rat Fly
regulation of tissue remodeling GO:0034103 2 0.040
organelle organization GO:0006996 227 0.040
regulation of response to stimulus GO:0048583 269 0.040
Rat Fly
larval development GO:0002164 2 0.038
heterocycle metabolic process GO:0046483 290 0.038
homeostatic process GO:0042592 142 0.038
hormone transport GO:0009914 2 0.038
rna metabolic process GO:0016070 219 0.035
regulation of bone remodeling GO:0046850 2 0.035
locomotion GO:0040011 313 0.035
digestive system development GO:0055123 289 0.034
vasculature development GO:0001944 278 0.033
cellular lipid metabolic process GO:0044255 36 0.033
regulation of multicellular organism growth GO:0040014 4 0.033
multicellular organism growth GO:0035264 4 0.033
regulation of cytokine production GO:0001817 3 0.032
response to lipid GO:0033993 60 0.032
cellular response to extracellular stimulus GO:0031668 2 0.032
regulation of hemostasis GO:1900046 1 0.032
brain development GO:0007420 293 0.032
glial cell migration GO:0008347 3 0.032
tissue homeostasis GO:0001894 25 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.030
small molecule metabolic process GO:0044281 77 0.030
skeletal system development GO:0001501 181 0.029
single organism localization GO:1902578 225 0.029
growth GO:0040007 174 0.029
response to hexose GO:0009746 3 0.028
developmental growth GO:0048589 166 0.028
central nervous system neuron differentiation GO:0021953 74 0.028
regulation of hormone secretion GO:0046883 2 0.028
positive regulation of map kinase activity GO:0043406 3 0.028
cellular response to organic substance GO:0071310 105 0.028
regulation of gene expression GO:0010468 265 0.027
Rat Fly
pancreas development GO:0031016 84 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
alpha amino acid metabolic process GO:1901605 3 0.026
cell motility GO:0048870 244 0.026
response to monosaccharide GO:0034284 3 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
Rat Fly
cellular component movement GO:0006928 335 0.026
insulin like growth factor receptor signaling pathway GO:0048009 4 0.025
regulation of wound healing GO:0061041 2 0.025
aging GO:0007568 2 0.025
immune system process GO:0002376 241 0.025
Fly
response to chemical GO:0042221 320 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.024
tube morphogenesis GO:0035239 349 0.024
positive regulation of cell substrate adhesion GO:0010811 1 0.024
cerebellar granular layer formation GO:0021684 3 0.024
toll like receptor signaling pathway GO:0002224 4 0.024
regulation of cell substrate adhesion GO:0010810 1 0.024
branched chain amino acid metabolic process GO:0009081 1 0.024
digestive tract development GO:0048565 265 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
cellular response to lipid GO:0071396 39 0.023
regulation of signal transduction GO:0009966 225 0.023
Fly
blood vessel development GO:0001568 246 0.023
positive regulation of cell adhesion GO:0045785 1 0.023
regulation of neurological system process GO:0031644 2 0.023
defense response to fungus GO:0050832 2 0.023
Fly
regulation of synapse assembly GO:0051963 3 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
regulation of catalytic activity GO:0050790 55 0.022
Rat Fly
maintenance of location GO:0051235 4 0.022
transport GO:0006810 220 0.022
cellular response to lipopolysaccharide GO:0071222 3 0.022
intestinal cholesterol absorption GO:0030299 2 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
regulation of cell death GO:0010941 103 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.021
cerebellum development GO:0021549 17 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
cell substrate adhesion GO:0031589 4 0.021
amine metabolic process GO:0009308 2 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
multi organism cellular process GO:0044764 2 0.021
hormone secretion GO:0046879 2 0.020
liver development GO:0001889 96 0.020
cellular response to nutrient levels GO:0031669 2 0.020
regulation of jak stat cascade GO:0046425 3 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
single organism transport GO:0044765 206 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
chordate embryonic development GO:0043009 271 0.020
establishment of localization GO:0051234 244 0.020
cerebellar cortex formation GO:0021697 5 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
organic substance biosynthetic process GO:1901576 289 0.019
establishment of blood brain barrier GO:0060856 2 0.019
negative regulation of nuclear division GO:0051784 3 0.019
peptide transport GO:0015833 1 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
digestive tract morphogenesis GO:0048546 231 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.019
cellular response to external stimulus GO:0071496 2 0.019
blood coagulation fibrin clot formation GO:0072378 3 0.019
regulation of cell communication GO:0010646 232 0.018
Fly
hindbrain morphogenesis GO:0021575 22 0.018
cerebellar granular layer development GO:0021681 3 0.018
cellular response to hormone stimulus GO:0032870 39 0.018
gtp catabolic process GO:0006184 2 0.018
head development GO:0060322 303 0.018
cellular response to biotic stimulus GO:0071216 3 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
iron ion transport GO:0006826 4 0.017
lipid storage GO:0019915 1 0.017
central nervous system myelination GO:0022010 2 0.017
response to organic substance GO:0010033 153 0.017
lipoprotein catabolic process GO:0042159 1 0.017
lymph vessel morphogenesis GO:0036303 25 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
multi organism process GO:0051704 134 0.017
Fly
single organism metabolic process GO:0044710 217 0.017
response to food GO:0032094 1 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.016
cellular amide metabolic process GO:0043603 4 0.016
female sex differentiation GO:0046660 4 0.016
stem cell maintenance GO:0019827 4 0.016
cellular aldehyde metabolic process GO:0006081 4 0.016
biosynthetic process GO:0009058 294 0.016
negative regulation of biological process GO:0048519 304 0.016
Rat Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
metencephalon development GO:0022037 27 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
cellular response to starvation GO:0009267 1 0.015
response to stress GO:0006950 263 0.015
Rat Fly
inner ear development GO:0048839 126 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
cellular protein catabolic process GO:0044257 4 0.015
cellular response to organic cyclic compound GO:0071407 38 0.015
response to carbohydrate GO:0009743 3 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
regulation of blood vessel size GO:0050880 2 0.015
cellular component disassembly GO:0022411 1 0.015
protein metabolic process GO:0019538 183 0.015
Rat Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
fertilization GO:0009566 3 0.015
regulation of synapse organization GO:0050807 3 0.014
response to ketone GO:1901654 1 0.014
osteoclast differentiation GO:0030316 1 0.014
cerebellar granular layer morphogenesis GO:0021683 3 0.014
cytosolic calcium ion transport GO:0060401 3 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
regeneration GO:0031099 91 0.014
regulation of cell activation GO:0050865 1 0.014
bone remodeling GO:0046849 2 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
central nervous system development GO:0007417 387 0.014
cellular modified amino acid metabolic process GO:0006575 3 0.014
regulation of protein catabolic process GO:0042176 1 0.014
positive regulation of cell activation GO:0050867 1 0.014
regulation of biological quality GO:0065008 263 0.014
negative regulation of dna replication GO:0008156 2 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.014
response to glucocorticoid GO:0051384 1 0.014
cellular protein metabolic process GO:0044267 129 0.013
regulation of cell projection assembly GO:0060491 4 0.013
blood vessel morphogenesis GO:0048514 216 0.013
regulation of apoptotic process GO:0042981 98 0.013
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
response to wounding GO:0009611 116 0.013
Rat
negative regulation of defense response GO:0031348 2 0.013
Rat
organonitrogen compound metabolic process GO:1901564 74 0.013
anatomical structure homeostasis GO:0060249 36 0.013
neurotransmitter transport GO:0006836 2 0.013
positive regulation of leukocyte differentiation GO:1902107 1 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
lipid digestion GO:0044241 3 0.013
cellular response to steroid hormone stimulus GO:0071383 31 0.013
regulation of cellular extravasation GO:0002691 1 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
regulation of rac protein signal transduction GO:0035020 1 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
regulation of biosynthetic process GO:0009889 250 0.012
receptor internalization GO:0031623 2 0.012
protein dephosphorylation GO:0006470 3 0.012
leukocyte differentiation GO:0002521 25 0.012
rna localization GO:0006403 4 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
regulation of erythrocyte differentiation GO:0045646 2 0.012
myeloid cell differentiation GO:0030099 86 0.012
cellular response to prostaglandin stimulus GO:0071379 3 0.012
lymphocyte proliferation GO:0046651 1 0.012
adult behavior GO:0030534 2 0.012
glucose import GO:0046323 2 0.012
regulation of jun kinase activity GO:0043506 3 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
positive regulation of transport GO:0051050 2 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
beta amyloid formation GO:0034205 1 0.012
gastrulation GO:0007369 208 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
regulation of inflammatory response GO:0050727 2 0.012
Rat
cellular response to xenobiotic stimulus GO:0071466 35 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
regulation of multicellular organismal process GO:0051239 277 0.011
localization of cell GO:0051674 244 0.011
response to organic cyclic compound GO:0014070 51 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
positive regulation of blood circulation GO:1903524 2 0.011
programmed cell death GO:0012501 119 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
nucleic acid metabolic process GO:0090304 244 0.011
intracellular mrna localization GO:0008298 1 0.011
positive regulation of cell division GO:0051781 2 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
axon ensheathment in central nervous system GO:0032291 2 0.011
positive regulation of catabolic process GO:0009896 4 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
interspecies interaction between organisms GO:0044419 4 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
regulation of metal ion transport GO:0010959 4 0.011
angiogenesis GO:0001525 158 0.011
skeletal system morphogenesis GO:0048705 102 0.011
death GO:0016265 121 0.011
lipid homeostasis GO:0055088 3 0.011
sequestering of metal ion GO:0051238 3 0.011
transcription dna templated GO:0006351 181 0.011
regulation of fatty acid metabolic process GO:0019217 1 0.011
gtp metabolic process GO:0046039 4 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
phagocytosis GO:0006909 3 0.011
positive regulation of synapse assembly GO:0051965 1 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
female gonad development GO:0008585 4 0.011
cellular response to stress GO:0033554 62 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
g protein coupled receptor signaling pathway GO:0007186 74 0.010
positive regulation of epithelial cell proliferation GO:0050679 1 0.010
cell matrix adhesion GO:0007160 4 0.010
cellular extravasation GO:0045123 1 0.010
rna biosynthetic process GO:0032774 181 0.010
cellular response to fatty acid GO:0071398 3 0.010
regulation of molecular function GO:0065009 70 0.010
Rat Fly
negative regulation of multi organism process GO:0043901 3 0.010
cell substrate junction assembly GO:0007044 2 0.010
cerebellar cortex development GO:0021695 5 0.010
regulation of response to biotic stimulus GO:0002831 2 0.010
nuclear division GO:0000280 23 0.010

serpinc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.049
inherited metabolic disorder DOID:655 0 0.049
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
lipid metabolism disorder DOID:3146 0 0.011