Danio rerio

23 known processes

setd8a

SET domain containing (lysine methyltransferase) 8a

(Aliases: MGC153719,wu:fj33f02,set8a,zgc:153719)

setd8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 224 0.858
Human
nucleic acid metabolic process GO:0090304 244 0.559
Human Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.504
Human
negative regulation of cellular process GO:0048523 283 0.500
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.479
Human
rna biosynthetic process GO:0032774 181 0.422
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.402
Human Fly
regulation of primary metabolic process GO:0080090 311 0.398
Human
regulation of cellular metabolic process GO:0031323 320 0.345
Human
cellular aromatic compound metabolic process GO:0006725 295 0.309
Human Fly
cellular biosynthetic process GO:0044249 286 0.285
Human
organic substance biosynthetic process GO:1901576 289 0.274
Human
histone h4 k20 methylation GO:0034770 2 0.263
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.250
Human
regulation of metabolic process GO:0019222 359 0.243
nitrogen compound metabolic process GO:0006807 319 0.228
Human Fly
peptidyl lysine methylation GO:0018022 3 0.224
Human Fly
stem cell maintenance GO:0019827 4 0.201
transcription dna templated GO:0006351 181 0.200
Human
cellular macromolecule metabolic process GO:0044260 391 0.185
Human Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.179
Human
response to chemical GO:0042221 320 0.176
regulation of cellular biosynthetic process GO:0031326 245 0.171
Human
organic cyclic compound metabolic process GO:1901360 301 0.170
Human Fly
heterocycle biosynthetic process GO:0018130 215 0.169
Human
erythrocyte homeostasis GO:0034101 55 0.162
regulation of biosynthetic process GO:0009889 250 0.161
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.156
Human
regulation of macromolecule metabolic process GO:0060255 317 0.153
aromatic compound biosynthetic process GO:0019438 217 0.142
Human
regulation of signal transduction GO:0009966 225 0.141
Human
regulation of meiotic cell cycle GO:0051445 1 0.136
organelle organization GO:0006996 227 0.136
Human Fly
gene expression GO:0010467 252 0.132
biosynthetic process GO:0009058 294 0.132
Human
multi organism process GO:0051704 134 0.126
nucleobase containing compound biosynthetic process GO:0034654 205 0.126
Human
heterocycle metabolic process GO:0046483 290 0.125
Human Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.115
cellular component morphogenesis GO:0032989 336 0.113
cell growth GO:0016049 57 0.107
regulation of epithelial cell proliferation GO:0050678 3 0.106
regulation of cellular amine metabolic process GO:0033238 0 0.106
rna metabolic process GO:0016070 219 0.101
Human
regulation of cell communication GO:0010646 232 0.100
Human
signal transduction GO:0007165 455 0.100
Human
chromatin modification GO:0016568 21 0.098
Human Fly
homeostatic process GO:0042592 142 0.097
single organism metabolic process GO:0044710 217 0.095
Human Fly
macromolecule biosynthetic process GO:0009059 227 0.095
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.094
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.088
Human
negative regulation of biological process GO:0048519 304 0.087
Human
neuron development GO:0048666 262 0.087
histone h3 k36 methylation GO:0010452 2 0.086
meiotic nuclear division GO:0007126 4 0.085
somite development GO:0061053 96 0.084
nucleobase containing compound metabolic process GO:0006139 274 0.083
Human Fly
cell morphogenesis GO:0000902 289 0.082
embryo development ending in birth or egg hatching GO:0009792 271 0.081
larval development GO:0002164 2 0.081
cellular response to nutrient levels GO:0031669 2 0.080
digestive tract morphogenesis GO:0048546 231 0.077
response to drug GO:0042493 3 0.075
regulation of signaling GO:0023051 235 0.075
Human
histone lysine methylation GO:0034968 12 0.074
Human Fly
response to stress GO:0006950 263 0.070
Human Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.067
Human
regulation of response to stimulus GO:0048583 269 0.067
Human
germ line stem cell maintenance GO:0030718 2 0.066
regulation of nucleic acid templated transcription GO:1903506 213 0.064
Human
heart development GO:0007507 313 0.062
stem cell development GO:0048864 82 0.061
aging GO:0007568 2 0.060
regulation of transcription dna templated GO:0006355 213 0.059
Human
adult behavior GO:0030534 2 0.056
negative regulation of gene expression GO:0010629 65 0.055
Human
gastrulation GO:0007369 208 0.055
cellular component biogenesis GO:0044085 178 0.055
cellular protein metabolic process GO:0044267 129 0.055
Human Fly
histone h3 k4 methylation GO:0051568 2 0.054
regulation of anterior head development GO:2000742 2 0.054
nucleic acid templated transcription GO:0097659 181 0.053
Human
digestive system development GO:0055123 289 0.052
regulation of rna biosynthetic process GO:2001141 213 0.051
Human
cell projection organization GO:0030030 284 0.051
mesoderm development GO:0007498 88 0.050
chordate embryonic development GO:0043009 271 0.050
negative regulation of biosynthetic process GO:0009890 55 0.050
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.046
cell projection morphogenesis GO:0048858 244 0.046
somitogenesis GO:0001756 87 0.045
nuclear import GO:0051170 3 0.043
dna catabolic process GO:0006308 1 0.043
mitotic cell cycle embryonic GO:0045448 2 0.043
cell part morphogenesis GO:0032990 246 0.043
cell migration involved in gastrulation GO:0042074 79 0.043
bmp signaling pathway GO:0030509 52 0.042
hemopoiesis GO:0030097 183 0.042
negative regulation of cellular metabolic process GO:0031324 77 0.041
Human
homeostasis of number of cells GO:0048872 62 0.041
regulation of gene expression GO:0010468 265 0.041
neuron projection morphogenesis GO:0048812 161 0.041
generation of neurons GO:0048699 385 0.040
regulation of biological quality GO:0065008 263 0.040
histone modification GO:0016570 20 0.040
Human Fly
cellular protein modification process GO:0006464 100 0.040
Human Fly
amine metabolic process GO:0009308 2 0.039
neuron projection development GO:0031175 180 0.038
covalent chromatin modification GO:0016569 20 0.038
Human Fly
determination of ventral identity GO:0048264 21 0.037
cellular macromolecular complex assembly GO:0034622 24 0.036
mesenchyme development GO:0060485 127 0.036
locomotion GO:0040011 313 0.035
dna alkylation GO:0006305 8 0.035
cellular component movement GO:0006928 335 0.035
response to glucocorticoid GO:0051384 1 0.034
single organism nuclear import GO:1902593 3 0.034
response to organic substance GO:0010033 153 0.033
myeloid cell homeostasis GO:0002262 56 0.033
cell death in response to oxidative stress GO:0036473 2 0.033
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.033
Human
negative regulation of metabolic process GO:0009892 86 0.033
Human
positive regulation of cell cycle GO:0045787 3 0.033
cytokinesis GO:0000910 3 0.032
protein modification process GO:0036211 100 0.032
Human Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.032
Human
regulation of catalytic activity GO:0050790 55 0.031
anterior posterior pattern specification GO:0009952 152 0.031
hematopoietic or lymphoid organ development GO:0048534 191 0.030
embryonic heart tube development GO:0035050 133 0.030
cell fate commitment GO:0045165 99 0.030
nuclear transport GO:0051169 4 0.030
growth GO:0040007 174 0.029
organonitrogen compound metabolic process GO:1901564 74 0.029
protein import GO:0017038 3 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
segmentation GO:0035282 97 0.028
single organism biosynthetic process GO:0044711 71 0.028
positive regulation of transport GO:0051050 2 0.028
phosphate containing compound metabolic process GO:0006796 108 0.028
cellular amine metabolic process GO:0044106 2 0.028
peptidyl lysine trimethylation GO:0018023 1 0.028
maintenance of location GO:0051235 4 0.028
phosphorus metabolic process GO:0006793 109 0.027
regulation of protein import into nucleus GO:0042306 2 0.027
glucose homeostasis GO:0042593 1 0.027
myeloid cell differentiation GO:0030099 86 0.027
mitochondrion organization GO:0007005 4 0.027
digestive tract mesoderm development GO:0007502 1 0.027
mesenchymal cell development GO:0014031 78 0.027
single organism reproductive process GO:0044702 40 0.027
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.027
stem cell differentiation GO:0048863 117 0.027
cellular response to chemical stimulus GO:0070887 157 0.026
death GO:0016265 121 0.026
convergent extension involved in organogenesis GO:0060029 10 0.025
response to hexose GO:0009746 3 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
Human
neuron differentiation GO:0030182 353 0.025
convergent extension GO:0060026 118 0.025
negative regulation of signal transduction GO:0009968 94 0.025
digestive tract development GO:0048565 265 0.025
regulation of cellular component organization GO:0051128 86 0.024
cellular carbohydrate metabolic process GO:0044262 4 0.024
regulation of mrna processing GO:0050684 3 0.024
cell migration GO:0016477 237 0.024
negative regulation of epithelial cell proliferation GO:0050680 1 0.024
positive regulation of dna metabolic process GO:0051054 1 0.024
regulation of translational initiation GO:0006446 1 0.024
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.024
macromolecular complex assembly GO:0065003 35 0.023
macromolecule modification GO:0043412 111 0.023
Human Fly
regulation of sequestering of calcium ion GO:0051282 4 0.023
embryonic skeletal joint morphogenesis GO:0060272 3 0.023
alternative mrna splicing via spliceosome GO:0000380 1 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.023
Human
neurotransmitter transport GO:0006836 2 0.023
regulation of cellular response to oxidative stress GO:1900407 2 0.023
spindle assembly GO:0051225 2 0.023
cell cycle arrest GO:0007050 1 0.023
response to external stimulus GO:0009605 264 0.023
localization of cell GO:0051674 244 0.022
developmental growth GO:0048589 166 0.022
multi organism reproductive process GO:0044703 36 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
chromatin organization GO:0006325 22 0.022
Human Fly
regulation of establishment of protein localization GO:0070201 4 0.022
heart morphogenesis GO:0003007 156 0.022
dna methylation GO:0006306 8 0.022
establishment of protein localization to organelle GO:0072594 4 0.021
regulation of organelle organization GO:0033043 29 0.021
negative regulation of meiotic cell cycle GO:0051447 1 0.021
dna methylation or demethylation GO:0044728 8 0.021
negative regulation of transcription dna templated GO:0045892 45 0.021
Human
macromolecule methylation GO:0043414 19 0.021
Human Fly
cellular response to organic substance GO:0071310 105 0.020
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.020
energy reserve metabolic process GO:0006112 2 0.020
embryonic limb morphogenesis GO:0030326 2 0.020
specification of symmetry GO:0009799 204 0.020
positive regulation of developmental process GO:0051094 50 0.020
meiotic cell cycle process GO:1903046 3 0.020
protein localization to nucleus GO:0034504 3 0.020
sequestering of calcium ion GO:0051208 3 0.020
cardiac atrium development GO:0003230 4 0.020
protein targeting to nucleus GO:0044744 3 0.020
regulation of response to stress GO:0080134 36 0.019
Human
single organism organelle organization GO:1902589 199 0.019
Human Fly
organic acid metabolic process GO:0006082 31 0.019
regulation of mesoderm development GO:2000380 11 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
Human
central nervous system neuron development GO:0021954 29 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
stem cell division GO:0017145 1 0.018
negative regulation of nuclear division GO:0051784 3 0.018
positive regulation of catabolic process GO:0009896 4 0.018
recombinational repair GO:0000725 1 0.018
regulation of developmental process GO:0050793 247 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
axon development GO:0061564 166 0.017
ovarian follicle development GO:0001541 2 0.017
establishment of localization GO:0051234 244 0.017
muscle organ development GO:0007517 101 0.017
multicellular organism reproduction GO:0032504 35 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
regulation of mrna splicing via spliceosome GO:0048024 3 0.017
meiotic spindle organization GO:0000212 1 0.017
histone methylation GO:0016571 13 0.017
Human Fly
tube morphogenesis GO:0035239 349 0.017
phosphorylation GO:0016310 69 0.017
cardiac atrium morphogenesis GO:0003209 2 0.017
regulation of synapse assembly GO:0051963 3 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
regulation of cellular component movement GO:0051270 55 0.017
programmed cell death GO:0012501 119 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
muscle tissue development GO:0060537 110 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
carbohydrate homeostasis GO:0033500 1 0.016
regulation of erythrocyte differentiation GO:0045646 2 0.016
protein complex assembly GO:0006461 30 0.016
positive regulation of chromatin modification GO:1903310 1 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
muscle cell differentiation GO:0042692 139 0.016
response to monosaccharide GO:0034284 3 0.016
regulation of response to oxidative stress GO:1902882 2 0.016
dna modification GO:0006304 8 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
negative regulation of locomotion GO:0040013 18 0.016
cellular response to dna damage stimulus GO:0006974 24 0.016
Human Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.016
cellular response to starvation GO:0009267 1 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
immune system process GO:0002376 241 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
striated muscle tissue development GO:0014706 110 0.016
cellular response to stress GO:0033554 62 0.015
Human Fly
organelle transport along microtubule GO:0072384 1 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
skeletal system development GO:0001501 181 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
methylation GO:0032259 22 0.015
Human Fly
small molecule metabolic process GO:0044281 77 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
regulation of cell development GO:0060284 100 0.015
embryonic skeletal system morphogenesis GO:0048704 93 0.015
sequestering of metal ion GO:0051238 3 0.015
spindle assembly involved in mitosis GO:0090307 1 0.015
regulation of phosphate metabolic process GO:0019220 43 0.015
protein metabolic process GO:0019538 183 0.015
Human Fly
cell aging GO:0007569 2 0.015
regulation of histone methylation GO:0031060 3 0.015
macromolecule localization GO:0033036 54 0.014
ncrna metabolic process GO:0034660 12 0.014
regulation of phosphorylation GO:0042325 26 0.014
response to corticosteroid GO:0031960 1 0.014
female gonad development GO:0008585 4 0.014
positive regulation of mrna metabolic process GO:1903313 2 0.014
taxis GO:0042330 109 0.014
fat soluble vitamin metabolic process GO:0006775 4 0.014
muscle structure development GO:0061061 196 0.014
wnt signaling pathway GO:0016055 80 0.014
phagocytosis GO:0006909 3 0.014
regulation of protein targeting GO:1903533 2 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
regulation of mrna catabolic process GO:0061013 3 0.014
positive regulation of myeloid cell differentiation GO:0045639 2 0.013
sexual reproduction GO:0019953 36 0.013
regulation of tube size GO:0035150 2 0.013
mitochondrial transport GO:0006839 2 0.013
regulation of binding GO:0051098 3 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
Human Fly
nucleobase containing compound catabolic process GO:0034655 15 0.013
response to external biotic stimulus GO:0043207 97 0.013
regulation of synapse organization GO:0050807 3 0.013
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.013
negative regulation of signaling GO:0023057 96 0.013
striated muscle cell development GO:0055002 108 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
ameboidal type cell migration GO:0001667 143 0.013
germ line stem cell division GO:0042078 1 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
aromatic compound catabolic process GO:0019439 15 0.013
positive regulation of histone modification GO:0031058 1 0.013
septum transversum development GO:0003343 4 0.013
protein import into nucleus GO:0006606 3 0.013
anterior head development GO:0097065 2 0.013
response to carbohydrate GO:0009743 3 0.013
response to glucose GO:0009749 3 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.013
oxoacid metabolic process GO:0043436 31 0.013
regulation of cell differentiation GO:0045595 142 0.012
gtp catabolic process GO:0006184 2 0.012
embryonic skeletal joint development GO:0072498 3 0.012
axonogenesis GO:0007409 152 0.012
positive regulation of multi organism process GO:0043902 3 0.012
positive regulation of embryonic development GO:0040019 3 0.012
negative regulation of cell migration GO:0030336 17 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
behavior GO:0007610 74 0.012
intracellular signal transduction GO:0035556 85 0.012
Human
determination of bilateral symmetry GO:0009855 204 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
cellular ketone metabolic process GO:0042180 11 0.012
viral process GO:0016032 1 0.012
reproductive process GO:0022414 40 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
neurotransmitter secretion GO:0007269 2 0.012
erythrocyte differentiation GO:0030218 54 0.011
regulation of oxidative stress induced cell death GO:1903201 2 0.011
golgi organization GO:0007030 1 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
palate development GO:0060021 8 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
heterocycle catabolic process GO:0046700 15 0.011
response to amine GO:0014075 1 0.011
regulation of protein kinase activity GO:0045859 15 0.011
muscle cell migration GO:0014812 4 0.011
negative regulation of cellular component movement GO:0051271 18 0.011
cognition GO:0050890 1 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
cell cell signaling GO:0007267 52 0.011
positive regulation of metabolic process GO:0009893 108 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
regulation of protein complex assembly GO:0043254 3 0.011
cellular component disassembly GO:0022411 1 0.011
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.011
sensory system development GO:0048880 76 0.011
regulation of programmed cell death GO:0043067 101 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
synaptic vesicle localization GO:0097479 1 0.010
determination of left right symmetry GO:0007368 179 0.010
embryonic heart tube morphogenesis GO:0003143 108 0.010
cell motility GO:0048870 244 0.010
female meiosis chromosome segregation GO:0016321 1 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
negative regulation of catabolic process GO:0009895 3 0.010
posttranscriptional regulation of gene expression GO:0010608 14 0.010
regulation of gene silencing GO:0060968 1 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
Human
determination of dorsal ventral asymmetry GO:0048262 34 0.010
translational initiation GO:0006413 3 0.010
female meiotic division GO:0007143 2 0.010

setd8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
neurodegenerative disease DOID:1289 0 0.014
central nervous system disease DOID:331 0 0.014
disease of cellular proliferation DOID:14566 0 0.012