Danio rerio

0 known processes

sf3a1

splicing factor 3a, subunit 1

(Aliases: wu:fc50a11,MGC65786,si:dz150f13.2,wu:fc38e01,MGC77239,wu:fj37c05,zgc:65786)

sf3a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 4 0.297
Worm
regulation of metabolic process GO:0019222 359 0.289
Worm Fly
aging GO:0007568 2 0.206
regulation of meiotic cell cycle GO:0051445 1 0.203
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.200
Human Fly
rna metabolic process GO:0016070 219 0.193
Human Fly
organic cyclic compound metabolic process GO:1901360 301 0.188
Human Fly
regulation of primary metabolic process GO:0080090 311 0.146
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.129
Human Fly
nuclear division GO:0000280 23 0.124
Worm Fly
gene expression GO:0010467 252 0.119
Human Worm Fly
larval development GO:0002164 2 0.097
heterocycle metabolic process GO:0046483 290 0.088
Human Fly
stem cell maintenance GO:0019827 4 0.088
regulation of developmental process GO:0050793 247 0.080
regulation of protein targeting GO:1903533 2 0.078
regulation of macromolecule metabolic process GO:0060255 317 0.076
Worm Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.073
Fly
positive regulation of cellular process GO:0048522 201 0.071
cellular macromolecule metabolic process GO:0044260 391 0.067
Human Fly
protein targeting to nucleus GO:0044744 3 0.064
regulation of cellular component organization GO:0051128 86 0.061
Worm
protein import into nucleus GO:0006606 3 0.060
organic cyclic compound biosynthetic process GO:1901362 223 0.059
regulation of protein localization to nucleus GO:1900180 2 0.058
positive regulation of cellular component biogenesis GO:0044089 3 0.058
positive regulation of transport GO:0051050 2 0.057
response to chemical GO:0042221 320 0.053
cellular aromatic compound metabolic process GO:0006725 295 0.053
Human Fly
regulation of cell shape GO:0008360 1 0.053
regulation of signal transduction GO:0009966 225 0.051
immune system process GO:0002376 241 0.051
protein complex disassembly GO:0043241 1 0.049
organelle organization GO:0006996 227 0.049
Worm Fly
nitrogen compound metabolic process GO:0006807 319 0.048
Human Fly
cellular biosynthetic process GO:0044249 286 0.047
organic substance biosynthetic process GO:1901576 289 0.047
response to drug GO:0042493 3 0.047
localization of cell GO:0051674 244 0.047
Worm
regulation of intracellular protein transport GO:0033157 3 0.046
regulation of multicellular organism growth GO:0040014 4 0.046
transport GO:0006810 220 0.045
Worm
protein localization to nucleus GO:0034504 3 0.045
regulation of establishment of protein localization GO:0070201 4 0.044
single organism nuclear import GO:1902593 3 0.044
macromolecule biosynthetic process GO:0009059 227 0.043
establishment of localization GO:0051234 244 0.043
Worm
maintenance of location GO:0051235 4 0.043
nuclear import GO:0051170 3 0.040
lipid storage GO:0019915 1 0.040
neuronal stem cell maintenance GO:0097150 2 0.040
regulation of nucleocytoplasmic transport GO:0046822 2 0.038
regulation of response to stimulus GO:0048583 269 0.038
response to stress GO:0006950 263 0.038
regulation of cellular metabolic process GO:0031323 320 0.038
Fly
negative regulation of cellular process GO:0048523 283 0.037
synaptic growth at neuromuscular junction GO:0051124 2 0.037
establishment of protein localization to organelle GO:0072594 4 0.036
cell cycle process GO:0022402 53 0.036
Worm Fly
regulation of mrna splicing via spliceosome GO:0048024 3 0.036
Fly
protein import GO:0017038 3 0.036
positive regulation of biological process GO:0048518 253 0.035
organonitrogen compound metabolic process GO:1901564 74 0.035
rna catabolic process GO:0006401 7 0.035
signal transduction GO:0007165 455 0.035
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.034
multi organism process GO:0051704 134 0.034
Worm
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.033
regulation of synapse organization GO:0050807 3 0.033
regulation of rna metabolic process GO:0051252 224 0.033
Fly
development of primary female sexual characteristics GO:0046545 4 0.032
regulation of cellular amine metabolic process GO:0033238 0 0.032
immune system development GO:0002520 191 0.031
meiotic cell cycle process GO:1903046 3 0.031
proteasomal protein catabolic process GO:0010498 2 0.031
locomotion GO:0040011 313 0.030
Worm
negative regulation of gene expression GO:0010629 65 0.030
Worm
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.030
Fly
regulation of protein transport GO:0051223 3 0.030
nucleic acid metabolic process GO:0090304 244 0.029
Human Fly
heterocycle biosynthetic process GO:0018130 215 0.029
multicellular organism growth GO:0035264 4 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.029
female sex differentiation GO:0046660 4 0.029
macromolecular complex subunit organization GO:0043933 74 0.029
Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.029
cellular amine metabolic process GO:0044106 2 0.029
regulation of cell differentiation GO:0045595 142 0.028
aromatic compound biosynthetic process GO:0019438 217 0.028
transcription dna templated GO:0006351 181 0.028
mitotic g2 dna damage checkpoint GO:0007095 3 0.028
female gonad development GO:0008585 4 0.027
regulation of erk1 and erk2 cascade GO:0070372 4 0.027
response to organic substance GO:0010033 153 0.027
regulation of mrna processing GO:0050684 3 0.027
Fly
homeostatic process GO:0042592 142 0.027
regulation of biosynthetic process GO:0009889 250 0.026
regulation of synapse assembly GO:0051963 3 0.026
regulation of response to nutrient levels GO:0032107 1 0.026
cell migration GO:0016477 237 0.026
Worm
cellular response to external stimulus GO:0071496 2 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
amine metabolic process GO:0009308 2 0.025
single organism organelle organization GO:1902589 199 0.025
Fly
meiosis i GO:0007127 1 0.025
multicellular organism reproduction GO:0032504 35 0.024
Worm
transcription from rna polymerase ii promoter GO:0006366 80 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.024
positive regulation of catabolic process GO:0009896 4 0.024
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.024
g2 dna damage checkpoint GO:0031572 3 0.023
regionalization GO:0003002 274 0.023
negative regulation of biological process GO:0048519 304 0.023
Worm
rna processing GO:0006396 25 0.023
Human Fly
regulation of reproductive process GO:2000241 4 0.022
myeloid cell differentiation GO:0030099 86 0.022
oxoacid metabolic process GO:0043436 31 0.022
single organism metabolic process GO:0044710 217 0.022
intracellular signal transduction GO:0035556 85 0.022
hemopoiesis GO:0030097 183 0.022
vesicle mediated transport GO:0016192 22 0.022
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.022
Worm
regulation of cell division GO:0051302 12 0.021
Worm
regulation of response to cytokine stimulus GO:0060759 3 0.021
erythrocyte differentiation GO:0030218 54 0.021
cellular protein catabolic process GO:0044257 4 0.021
macromolecule modification GO:0043412 111 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
rna biosynthetic process GO:0032774 181 0.021
regulation of dna replication GO:0006275 3 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
positive regulation of metabolic process GO:0009893 108 0.020
positive regulation of chromosome organization GO:2001252 1 0.020
cellular response to nutrient levels GO:0031669 2 0.020
cellular response to organic substance GO:0071310 105 0.020
cellular component movement GO:0006928 335 0.020
Worm
regulation of cellular biosynthetic process GO:0031326 245 0.020
primary neural tube formation GO:0014020 1 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
Fly
regulation of gene expression epigenetic GO:0040029 11 0.020
Worm
cellular component disassembly GO:0022411 1 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
negative regulation of defense response GO:0031348 2 0.019
single organism biosynthetic process GO:0044711 71 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
regulation of cell communication GO:0010646 232 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
regulation of cell cycle GO:0051726 52 0.019
Worm
dsrna fragmentation GO:0031050 1 0.018
mitotic sister chromatid segregation GO:0000070 6 0.018
cellular response to starvation GO:0009267 1 0.018
mitotic dna integrity checkpoint GO:0044774 4 0.018
positive regulation of cell activation GO:0050867 1 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
positive regulation of chromatin modification GO:1903310 1 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
cell morphogenesis GO:0000902 289 0.018
cell cycle GO:0007049 93 0.018
Worm Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.018
Fly
small molecule metabolic process GO:0044281 77 0.017
embryonic organ development GO:0048568 381 0.017
positive regulation of cell cycle GO:0045787 3 0.017
organic acid metabolic process GO:0006082 31 0.017
regulation of protein catabolic process GO:0042176 1 0.017
cellular component morphogenesis GO:0032989 336 0.017
tissue remodeling GO:0048771 4 0.017
regulation of cell activation GO:0050865 1 0.017
multicellular organismal metabolic process GO:0044236 2 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
nuclear transport GO:0051169 4 0.017
regulation of response to extracellular stimulus GO:0032104 1 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
biosynthetic process GO:0009058 294 0.016
regulation of signaling GO:0023051 235 0.016
regulation of translational initiation GO:0006446 1 0.016
growth GO:0040007 174 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
anterior posterior pattern specification GO:0009952 152 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
ovulation cycle GO:0042698 2 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
rna modification GO:0009451 2 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
regulation of biomineral tissue development GO:0070167 2 0.016
embryonic organ morphogenesis GO:0048562 274 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
regulation of gene expression GO:0010468 265 0.015
Worm Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
mrna metabolic process GO:0016071 20 0.015
Human Fly
positive regulation of histone modification GO:0031058 1 0.015
locomotor rhythm GO:0045475 3 0.015
pole plasm assembly GO:0007315 4 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
chordate embryonic development GO:0043009 271 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
organism emergence from protective structure GO:0071684 4 0.014
erythrocyte homeostasis GO:0034101 55 0.014
cell death GO:0008219 121 0.014
single organism localization GO:1902578 225 0.014
mrna processing GO:0006397 14 0.014
Human Fly
regulation of oocyte development GO:0060281 3 0.014
cell motility GO:0048870 244 0.014
Worm
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
myeloid cell homeostasis GO:0002262 56 0.014
lipid biosynthetic process GO:0008610 22 0.014
mitochondrion organization GO:0007005 4 0.014
autophagy GO:0006914 4 0.014
defense response to other organism GO:0098542 33 0.014
cell division GO:0051301 20 0.014
Worm
rna splicing via transesterification reactions GO:0000375 10 0.014
Human Fly
negative regulation of mitosis GO:0045839 3 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
skeletal system development GO:0001501 181 0.014
positive regulation of response to stimulus GO:0048584 80 0.013
morphogenesis of an epithelial fold GO:0060571 1 0.013
cellular response to organic cyclic compound GO:0071407 38 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
cytokinesis GO:0000910 3 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
stem cell differentiation GO:0048863 117 0.013
developmental maturation GO:0021700 34 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
cell death in response to oxidative stress GO:0036473 2 0.013
meiotic chromosome segregation GO:0045132 3 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
cell part morphogenesis GO:0032990 246 0.013
blood vessel morphogenesis GO:0048514 216 0.013
reproductive process GO:0022414 40 0.013
Worm
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
cellular protein metabolic process GO:0044267 129 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
negative regulation of innate immune response GO:0045824 2 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
Worm
negative regulation of protein phosphorylation GO:0001933 4 0.012
regulation of tor signaling GO:0032006 7 0.012
response to biotic stimulus GO:0009607 97 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
response to uv GO:0009411 3 0.012
lateral inhibition GO:0046331 1 0.012
positive regulation of signal transduction GO:0009967 56 0.012
negative regulation of mrna metabolic process GO:1903312 3 0.012
protein acetylation GO:0006473 2 0.012
oocyte anterior posterior axis specification GO:0007314 4 0.012
behavior GO:0007610 74 0.012
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.012
embryonic skeletal system development GO:0048706 97 0.012
centrosome duplication GO:0051298 1 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
negative regulation of metabolic process GO:0009892 86 0.012
Worm
b cell activation GO:0042113 2 0.012
gene silencing GO:0016458 4 0.012
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.012
gamete generation GO:0007276 33 0.012
Worm
negative regulation of programmed cell death GO:0043069 58 0.012
dna templated transcription elongation GO:0006354 3 0.012
response to external biotic stimulus GO:0043207 97 0.012
nuclear pore organization GO:0006999 2 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
apoptotic process GO:0006915 116 0.011
multi organism reproductive process GO:0044703 36 0.011
Worm
regulation of organelle organization GO:0033043 29 0.011
Worm
response to hormone GO:0009725 48 0.011
compound eye development GO:0048749 2 0.011
negative regulation of response to cytokine stimulus GO:0060761 2 0.011
cell matrix adhesion GO:0007160 4 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
programmed cell death GO:0012501 119 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
regulation of protein complex assembly GO:0043254 3 0.011
response to nutrient GO:0007584 3 0.011
wnt signaling pathway GO:0016055 80 0.011
response to hydrogen peroxide GO:0042542 3 0.011
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
single organism reproductive process GO:0044702 40 0.011
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
nucleic acid templated transcription GO:0097659 181 0.011
gtp catabolic process GO:0006184 2 0.011
negative regulation of multi organism process GO:0043901 3 0.011
macromolecular complex disassembly GO:0032984 1 0.011
tube closure GO:0060606 1 0.011
cellular response to stress GO:0033554 62 0.011
regulation of biological quality GO:0065008 263 0.011
centrosome cycle GO:0007098 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
intracellular mrna localization GO:0008298 1 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
regulation of programmed cell death GO:0043067 101 0.011
odontogenesis of dentin containing tooth GO:0042475 1 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
digestive system development GO:0055123 289 0.010
homeostasis of number of cells GO:0048872 62 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.010
camera type eye development GO:0043010 222 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
hepaticobiliary system development GO:0061008 98 0.010
mrna catabolic process GO:0006402 6 0.010
developmental growth GO:0048589 166 0.010
negative regulation of leukocyte differentiation GO:1902106 1 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.010
catabolic process GO:0009056 32 0.010
ovulation cycle process GO:0022602 2 0.010
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.010
regulation of bone mineralization GO:0030500 2 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
positive regulation of myeloid cell differentiation GO:0045639 2 0.010
positive regulation of synapse assembly GO:0051965 1 0.010
cellular response to dna damage stimulus GO:0006974 24 0.010
negative regulation of rna splicing GO:0033119 1 0.010
regulation of cellular response to oxidative stress GO:1900407 2 0.010

sf3a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.044
disease of cellular proliferation DOID:14566 0 0.044
organ system cancer DOID:0050686 0 0.044
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.022