Danio rerio

12 known processes

sfrp1a

secreted frizzled-related protein 1a

(Aliases: sfrp1,wu:fd19b09,MGC123001)

sfrp1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
optic placode formation GO:0001743 4 0.983
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.981
ectodermal placode morphogenesis GO:0071697 32 0.975
optic placode formation involved in camera type eye formation GO:0046619 3 0.936
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.932
Zebrafish
sensory organ development GO:0007423 393 0.828
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.782
Zebrafish
cellular component morphogenesis GO:0032989 336 0.740
Human Mouse
immune system process GO:0002376 241 0.709
Human Mouse
ectodermal placode development GO:0071696 37 0.688
pancreas development GO:0031016 84 0.685
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.673
rna biosynthetic process GO:0032774 181 0.673
Human
forebrain generation of neurons GO:0021872 14 0.670
brain development GO:0007420 293 0.646
Zebrafish
ectodermal placode formation GO:0060788 26 0.613
spinal cord radial glial cell differentiation GO:0021531 2 0.607
ear morphogenesis GO:0042471 64 0.598
sensory organ morphogenesis GO:0090596 200 0.591
negative regulation of gastrulation GO:2000542 11 0.575
gland development GO:0048732 143 0.557
Zebrafish Mouse
radial glial cell differentiation GO:0060019 2 0.533
epithelium regeneration GO:1990399 14 0.519
cell projection organization GO:0030030 284 0.513
embryonic pectoral fin morphogenesis GO:0035118 24 0.509
negative regulation of cell fate commitment GO:0010454 13 0.499
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.490
embryonic organ morphogenesis GO:0048562 274 0.475
embryonic organ development GO:0048568 381 0.463
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.461
regulation of canonical wnt signaling pathway GO:0060828 34 0.460
Human Mouse
sensory epithelium regeneration GO:0070654 14 0.459
gall bladder development GO:0061010 1 0.454
hepatocyte proliferation GO:0072574 2 0.440
macromolecule biosynthetic process GO:0009059 227 0.433
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.430
Human
liver development GO:0001889 96 0.427
Zebrafish
spinal cord anterior posterior patterning GO:0021512 1 0.425
endocrine pancreas development GO:0031018 27 0.424
neuron projection extension GO:1990138 45 0.417
response to chemical GO:0042221 320 0.406
Human Mouse
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.402
negative regulation of mitosis GO:0045839 3 0.396
negative regulation of nuclear division GO:0051784 3 0.391
regulation of catenin import into nucleus GO:0035412 2 0.385
non canonical wnt signaling pathway GO:0035567 13 0.383
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.374
Human
forebrain neuron differentiation GO:0021879 14 0.362
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.357
hepatic duct development GO:0061011 2 0.346
cellular biosynthetic process GO:0044249 286 0.345
Human
embryonic camera type eye development GO:0031076 29 0.330
forebrain development GO:0030900 96 0.328
Zebrafish
eye development GO:0001654 277 0.315
central nervous system development GO:0007417 387 0.311
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.311
regulation of wnt signaling pathway GO:0030111 53 0.309
Human Zebrafish Mouse
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.304
developmental induction GO:0031128 10 0.298
rna metabolic process GO:0016070 219 0.295
Human
neuron differentiation GO:0030182 353 0.291
eye morphogenesis GO:0048592 144 0.280
regulation of axon extension GO:0030516 24 0.279
cilium morphogenesis GO:0060271 85 0.268
protein metabolic process GO:0019538 183 0.267
Human Mouse
immune system development GO:0002520 191 0.261
Human Mouse
convergent extension involved in organogenesis GO:0060029 10 0.260
embryonic eye morphogenesis GO:0048048 30 0.259
wnt signaling pathway GO:0016055 80 0.257
Human Zebrafish Mouse
positive regulation of biological process GO:0048518 253 0.256
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.249
Mouse
death GO:0016265 121 0.248
Human Mouse
regulation of sequestering of calcium ion GO:0051282 4 0.245
otic placode formation GO:0043049 23 0.242
neuron development GO:0048666 262 0.239
organic cyclic compound metabolic process GO:1901360 301 0.236
Human
carboxylic acid metabolic process GO:0019752 22 0.232
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.230
otic vesicle morphogenesis GO:0071600 34 0.228
cell morphogenesis GO:0000902 289 0.223
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.221
Human Zebrafish Mouse
nucleic acid templated transcription GO:0097659 181 0.218
Human
tissue regeneration GO:0042246 74 0.217
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.217
Human Mouse
negative chemotaxis GO:0050919 1 0.217
embryonic camera type eye formation GO:0060900 10 0.213
central nervous system neuron differentiation GO:0021953 74 0.208
pectoral fin development GO:0033339 50 0.207
regulation of gene expression GO:0010468 265 0.206
Human Mouse
ear development GO:0043583 127 0.204
endodermal cell fate determination GO:0007493 2 0.204
neuron projection guidance GO:0097485 86 0.197
axon extension GO:0048675 45 0.196
endocrine system development GO:0035270 65 0.196
regulation of gastrulation GO:0010470 24 0.195
reproductive process GO:0022414 40 0.192
Mouse
axonogenesis GO:0007409 152 0.190
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.189
Human
cell part morphogenesis GO:0032990 246 0.188
camera type eye development GO:0043010 222 0.184
specification of organ identity GO:0010092 2 0.182
apoptotic process GO:0006915 116 0.179
Human Mouse
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.179
Mouse
inner ear morphogenesis GO:0042472 63 0.178
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.178
Human
dorsal ventral axis specification GO:0009950 14 0.177
Human
maintenance of location GO:0051235 4 0.177
inner ear development GO:0048839 126 0.176
negative regulation of response to stimulus GO:0048585 104 0.173
Human Mouse
regulation of epithelial to mesenchymal transition GO:0010717 3 0.168
Human
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.167
regulation of biological quality GO:0065008 263 0.167
Human
response to endogenous stimulus GO:0009719 83 0.164
Human Mouse
blood vessel morphogenesis GO:0048514 216 0.164
negative regulation of protein phosphorylation GO:0001933 4 0.163
Human Mouse
homeostatic process GO:0042592 142 0.162
regulation of response to stimulus GO:0048583 269 0.162
Human Zebrafish Mouse
developmental cell growth GO:0048588 52 0.156
retinal ganglion cell axon guidance GO:0031290 35 0.153
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.153
Mouse
appendage morphogenesis GO:0035107 56 0.152
cellular macromolecule metabolic process GO:0044260 391 0.151
Human Mouse
epithelial tube morphogenesis GO:0060562 148 0.150
Mouse
camera type eye morphogenesis GO:0048593 108 0.146
negative regulation of biological process GO:0048519 304 0.144
Human Mouse
catenin import into nucleus GO:0035411 2 0.143
axon guidance GO:0007411 86 0.142
cell migration GO:0016477 237 0.141
Human
determination of heart left right asymmetry GO:0061371 117 0.140
regulation of reproductive process GO:2000241 4 0.140
Mouse
cilium organization GO:0044782 71 0.139
positive regulation of biosynthetic process GO:0009891 68 0.138
Human
negative regulation of embryonic development GO:0045992 11 0.137
nucleobase containing compound metabolic process GO:0006139 274 0.137
Human
heart looping GO:0001947 94 0.136
negative regulation of growth GO:0045926 10 0.130
Human Mouse
single organism organelle organization GO:1902589 199 0.130
cell projection morphogenesis GO:0048858 244 0.129
negative regulation of axon guidance GO:1902668 1 0.128
blood vessel development GO:0001568 246 0.126
regulation of stem cell differentiation GO:2000736 4 0.125
Human
axon development GO:0061564 166 0.123
positive regulation of cell fate commitment GO:0010455 1 0.122
regulation of macromolecule biosynthetic process GO:0010556 225 0.122
Human Mouse
developmental growth GO:0048589 166 0.121
Mouse
positive regulation of cell differentiation GO:0045597 30 0.120
Human
dorsal ventral pattern formation GO:0009953 125 0.120
Human
diencephalon development GO:0021536 58 0.120
morphogenesis of a branching epithelium GO:0061138 16 0.119
Mouse
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.118
Human
oxoacid metabolic process GO:0043436 31 0.118
thrombocyte differentiation GO:0002574 4 0.118
cellular ketone metabolic process GO:0042180 11 0.116
multicellular organism growth GO:0035264 4 0.114
morphogenesis of an epithelium GO:0002009 333 0.113
Mouse
nucleic acid metabolic process GO:0090304 244 0.112
Human
glial cell differentiation GO:0010001 42 0.112
response to stress GO:0006950 263 0.112
Human Mouse
cell death GO:0008219 121 0.111
Human Mouse
gliogenesis GO:0042063 45 0.111
negative regulation of wnt signaling pathway GO:0030178 30 0.111
Human Mouse
lateral line development GO:0048882 66 0.111
hormone transport GO:0009914 2 0.110
Human
determination of pancreatic left right asymmetry GO:0035469 11 0.110
neural plate regionalization GO:0060897 10 0.109
positive regulation of muscle tissue development GO:1901863 1 0.109
negative regulation of cell fate specification GO:0009996 11 0.108
divalent inorganic anion homeostasis GO:0072505 5 0.108
pectoral fin morphogenesis GO:0035138 29 0.107
regulation of kinase activity GO:0043549 15 0.107
Mouse
cell growth GO:0016049 57 0.106
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.106
development of primary female sexual characteristics GO:0046545 4 0.105
Mouse
positive regulation of jun kinase activity GO:0043507 2 0.104
nephron tubule morphogenesis GO:0072078 1 0.103
swim bladder development GO:0048794 19 0.102
positive regulation of transcription dna templated GO:0045893 57 0.102
Human
regulation of cell growth GO:0001558 29 0.102
Human
negative regulation of developmental process GO:0051093 65 0.102
Human Mouse
chemotaxis GO:0006935 104 0.100
angiogenesis GO:0001525 158 0.100
sequestering of calcium ion GO:0051208 3 0.099
negative regulation of cell migration GO:0030336 17 0.099
Human
regulation of signaling GO:0023051 235 0.099
Human Zebrafish Mouse
cellular component assembly involved in morphogenesis GO:0010927 107 0.098
lipid metabolic process GO:0006629 52 0.097
neural plate pattern specification GO:0060896 12 0.096
embryonic camera type eye morphogenesis GO:0048596 19 0.096
positive regulation of immune system process GO:0002684 17 0.096
cilium assembly GO:0042384 58 0.096
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.096
Human
regulation of cardiac muscle tissue development GO:0055024 1 0.096
retina development in camera type eye GO:0060041 146 0.095
developmental growth involved in morphogenesis GO:0060560 86 0.094
Mouse
otic vesicle formation GO:0030916 27 0.091
regulation of epithelial cell proliferation GO:0050678 3 0.091
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.090
Mouse
regulation of glial cell differentiation GO:0045685 4 0.090
regulation of ectodermal cell fate specification GO:0042665 2 0.087
aromatic compound biosynthetic process GO:0019438 217 0.087
Human
negative regulation of cellular component movement GO:0051271 18 0.087
Human
regulation of signal transduction GO:0009966 225 0.086
Human Zebrafish Mouse
canonical wnt signaling pathway GO:0060070 48 0.086
Human Mouse
positive regulation of signaling GO:0023056 56 0.086
Human Mouse
response to external stimulus GO:0009605 264 0.085
Human
sequestering of metal ion GO:0051238 3 0.084
regulation of embryonic development GO:0045995 47 0.084
Mouse
ectodermal cell fate specification GO:0001715 2 0.083
single organism reproductive process GO:0044702 40 0.083
Mouse
regulation of extent of cell growth GO:0061387 29 0.082
response to fibroblast growth factor GO:0071774 22 0.081
Human
positive regulation of response to stimulus GO:0048584 80 0.080
Human Mouse
negative regulation of sequestering of calcium ion GO:0051283 4 0.078
appendage development GO:0048736 80 0.078
neuron projection development GO:0031175 180 0.077
neuromast development GO:0048884 46 0.076
negative regulation of protein kinase activity GO:0006469 4 0.076
Mouse
anterior head development GO:0097065 2 0.074
female gonad development GO:0008585 4 0.074
Mouse
activation of mapk activity GO:0000187 3 0.074
endoderm formation GO:0001706 29 0.074
embryonic pattern specification GO:0009880 44 0.073
neural tube development GO:0021915 62 0.073
Mouse
heterocycle metabolic process GO:0046483 290 0.073
Human
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.071
forebrain anterior posterior pattern specification GO:0021797 3 0.071
larval development GO:0002164 2 0.071
negative regulation of multicellular organismal process GO:0051241 69 0.070
Human Mouse
oocyte maturation GO:0001556 4 0.070
regulation of protein transport GO:0051223 3 0.070
regulation of cell communication GO:0010646 232 0.069
Human Zebrafish Mouse
regulation of cell migration GO:0030334 40 0.068
Human
phosphorylation GO:0016310 69 0.067
Human Mouse
organic acid metabolic process GO:0006082 31 0.067
regulation of anatomical structure size GO:0090066 33 0.067
olfactory lobe development GO:0021988 4 0.067
organic substance biosynthetic process GO:1901576 289 0.066
Human
regionalization GO:0003002 274 0.066
Human Mouse
negative regulation of non canonical wnt signaling pathway GO:2000051 1 0.066
Mouse
peptide transport GO:0015833 1 0.065
Human
regulation of ectoderm development GO:2000383 2 0.064
response to wounding GO:0009611 116 0.064
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.064
Human
negative regulation of cell growth GO:0030308 7 0.063
Human
regulation of collateral sprouting in absence of injury GO:0048696 4 0.062
regulation of cell development GO:0060284 100 0.062
Human
regulation of intracellular protein transport GO:0033157 3 0.061
regulation of molecular function GO:0065009 70 0.061
Mouse
heterocycle biosynthetic process GO:0018130 215 0.061
Human
cell morphogenesis involved in differentiation GO:0000904 195 0.060
Human Mouse
negative regulation of endodermal cell differentiation GO:1903225 8 0.060
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.059
Human
regulation of endodermal cell fate specification GO:0042663 15 0.058
cell proliferation in forebrain GO:0021846 3 0.058
fin development GO:0033333 77 0.057
inner ear receptor cell differentiation GO:0060113 29 0.057
cerebellar granular layer development GO:0021681 3 0.056
phosphorus metabolic process GO:0006793 109 0.056
Human Mouse
otic vesicle development GO:0071599 42 0.056
cellular response to chemical stimulus GO:0070887 157 0.056
Human Mouse
nephron morphogenesis GO:0072028 2 0.055
regulation of cellular component size GO:0032535 30 0.055
cellular amino acid metabolic process GO:0006520 7 0.055
digestive system development GO:0055123 289 0.055
Zebrafish Mouse
regulation of cell cycle GO:0051726 52 0.054
Human
sensory system development GO:0048880 76 0.054
small molecule metabolic process GO:0044281 77 0.054
heart development GO:0007507 313 0.054
regulation of metabolic process GO:0019222 359 0.054
Human Mouse
taxis GO:0042330 109 0.054
neuroblast proliferation GO:0007405 2 0.053
mechanoreceptor differentiation GO:0042490 37 0.053
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.052
internal peptidyl lysine acetylation GO:0018393 2 0.052
wound healing GO:0042060 90 0.052
embryonic appendage morphogenesis GO:0035113 30 0.052
transport GO:0006810 220 0.051
Human
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.051
Human Mouse
cellular lipid metabolic process GO:0044255 36 0.051
kidney development GO:0001822 92 0.051
Mouse
midbrain hindbrain boundary development GO:0030917 23 0.050
cellular protein metabolic process GO:0044267 129 0.050
Human Mouse
anterior posterior axon guidance GO:0033564 5 0.050
regeneration GO:0031099 91 0.050
release of sequestered calcium ion into cytosol GO:0051209 3 0.050
wnt signaling pathway calcium modulating pathway GO:0007223 5 0.049
convergent extension GO:0060026 118 0.049
Mouse
urogenital system development GO:0001655 97 0.049
Mouse
hepaticobiliary system development GO:0061008 98 0.049
Zebrafish
mesodermal cell fate commitment GO:0001710 14 0.049
negative regulation of endodermal cell fate specification GO:0042664 8 0.048
cellular component biogenesis GO:0044085 178 0.048
generation of neurons GO:0048699 385 0.048
regulation of anatomical structure morphogenesis GO:0022603 130 0.048
Human Zebrafish Mouse
amine metabolic process GO:0009308 2 0.048
regulation of cell size GO:0008361 29 0.048
growth GO:0040007 174 0.048
Human Mouse
regulation of programmed cell death GO:0043067 101 0.048
Human Mouse
embryonic heart tube development GO:0035050 133 0.048
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.047
regulation of axon extension involved in axon guidance GO:0048841 6 0.047
negative regulation of gliogenesis GO:0014014 1 0.047
organic cyclic compound biosynthetic process GO:1901362 223 0.047
Human
connective tissue development GO:0061448 99 0.047
cellular amine metabolic process GO:0044106 2 0.047
kidney epithelium development GO:0072073 23 0.047
Mouse
branching morphogenesis of an epithelial tube GO:0048754 15 0.046
single organism metabolic process GO:0044710 217 0.046
Mouse
regulation of endodermal cell differentiation GO:1903224 15 0.046
enzyme linked receptor protein signaling pathway GO:0007167 106 0.045
Mouse
chordate embryonic development GO:0043009 271 0.045
Mouse
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.045
regulation of anterior head development GO:2000742 2 0.045
hematopoietic or lymphoid organ development GO:0048534 191 0.044
Human Mouse
renal system development GO:0072001 94 0.044
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.044
sensory perception of pain GO:0019233 1 0.044
stem cell development GO:0048864 82 0.043
Human Mouse
renal tubule morphogenesis GO:0061333 1 0.043
fourth ventricle development GO:0021592 8 0.042
positive regulation of map kinase activity GO:0043406 3 0.042
positive regulation of transport GO:0051050 2 0.042
stem cell maintenance GO:0019827 4 0.042
Mouse
cell migration to the midline involved in heart development GO:0003318 12 0.042
osteoblast differentiation GO:0001649 5 0.041
Human Mouse
meiotic nuclear division GO:0007126 4 0.041
transcription dna templated GO:0006351 181 0.041
Human
retina morphogenesis in camera type eye GO:0060042 79 0.041
hormone secretion GO:0046879 2 0.040
Human
pituitary gland development GO:0021983 16 0.040
regulation of mitotic cell cycle GO:0007346 25 0.040
response to glucocorticoid GO:0051384 1 0.040
regulation of dna replication GO:0006275 3 0.039
post anal tail morphogenesis GO:0036342 19 0.039
negative regulation of mapk cascade GO:0043409 4 0.039
Mouse
organelle assembly GO:0070925 110 0.039
cellular nitrogen compound metabolic process GO:0034641 290 0.039
Human
negative regulation of cell communication GO:0010648 96 0.039
Human Mouse
negative regulation of cellular process GO:0048523 283 0.039
Human Mouse
defense response to bacterium GO:0042742 22 0.038
hemopoiesis GO:0030097 183 0.038
Human Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.038
response to growth factor GO:0070848 39 0.038
Human
regulation of heart growth GO:0060420 2 0.038
negative regulation of myeloid cell differentiation GO:0045638 1 0.038
Mouse
regulation of jun kinase activity GO:0043506 3 0.038
Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.038
regulation of nervous system development GO:0051960 90 0.037
Mouse
cardioblast migration GO:0003260 7 0.037
negative regulation of neutrophil chemotaxis GO:0090024 3 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.037
Human
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.037
cartilage development GO:0051216 96 0.037
primitive erythrocyte differentiation GO:0060319 5 0.037
segmentation GO:0035282 97 0.036
Mouse
cellular protein modification process GO:0006464 100 0.036
Human Mouse
embryonic digestive tract morphogenesis GO:0048557 3 0.036
negative regulation of collateral sprouting GO:0048671 2 0.036
cellular amide metabolic process GO:0043603 4 0.035
positive regulation of apoptotic process GO:0043065 29 0.035
Human Mouse
mesenchyme development GO:0060485 127 0.035
Human Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.035
response to external biotic stimulus GO:0043207 97 0.035
spinal cord development GO:0021510 46 0.035
regulation of cell fate specification GO:0042659 20 0.035
regulation of cellular ketone metabolic process GO:0010565 7 0.035
negative regulation of cell cycle GO:0045786 14 0.035
epithalamus development GO:0021538 10 0.035
digestive tract morphogenesis GO:0048546 231 0.034
Zebrafish Mouse
lateral line system development GO:0048925 76 0.034
nitrogen compound metabolic process GO:0006807 319 0.034
Human
protein modification process GO:0036211 100 0.033
Human Mouse
negative regulation of stem cell differentiation GO:2000737 2 0.033
Human
cellular response to lipid GO:0071396 39 0.033
Human Mouse
positive regulation of striated muscle tissue development GO:0045844 1 0.033
skeletal system development GO:0001501 181 0.033
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.033
Mouse
regulation of locomotion GO:0040012 55 0.033
Human
regulation of catalytic activity GO:0050790 55 0.033
Mouse
response to nutrient GO:0007584 3 0.033
Human
organelle organization GO:0006996 227 0.033
nephron epithelium morphogenesis GO:0072088 1 0.033
regulation of developmental growth GO:0048638 38 0.033
Mouse
head development GO:0060322 303 0.033
Zebrafish
regulation of multicellular organismal development GO:2000026 223 0.032
Human Zebrafish Mouse
positive regulation of cell cycle GO:0045787 3 0.032
regulation of mesodermal cell fate specification GO:0042661 9 0.032
dorsal convergence GO:0060030 14 0.032
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.032
type b pancreatic cell proliferation GO:0044342 1 0.032
programmed cell death GO:0012501 119 0.032
Human Mouse
positive regulation of muscle organ development GO:0048636 1 0.031
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.031
Human
negative regulation of granulocyte chemotaxis GO:0071623 3 0.031
regulation of growth GO:0040008 42 0.031
Human Mouse
regulation of hormone levels GO:0010817 21 0.031
Human
embryonic limb morphogenesis GO:0030326 2 0.031
tube morphogenesis GO:0035239 349 0.031
Zebrafish Mouse
phosphate containing compound metabolic process GO:0006796 108 0.031
Human Mouse
endoderm development GO:0007492 49 0.031
positive regulation of nucleic acid templated transcription GO:1903508 57 0.031
Human
response to organic substance GO:0010033 153 0.031
Human Mouse
formation of primary germ layer GO:0001704 62 0.031
regulation of protein targeting GO:1903533 2 0.031
positive regulation of cell death GO:0010942 29 0.030
Human Mouse
oligodendrocyte differentiation GO:0048709 23 0.030
axon extension involved in axon guidance GO:0048846 10 0.030
somatic stem cell maintenance GO:0035019 1 0.030
Mouse
negative regulation of map kinase activity GO:0043407 2 0.030
Mouse
lymphocyte proliferation GO:0046651 1 0.030
cellular response to organic cyclic compound GO:0071407 38 0.029
Human Mouse
mononuclear cell proliferation GO:0032943 1 0.029
leukocyte proliferation GO:0070661 1 0.029
embryonic skeletal system development GO:0048706 97 0.029
carbohydrate derivative biosynthetic process GO:1901137 43 0.029
regulation of organ growth GO:0046620 3 0.029
regulation of nucleic acid templated transcription GO:1903506 213 0.029
Human Mouse
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.028
liver morphogenesis GO:0072576 8 0.028
Zebrafish
positive regulation of embryonic development GO:0040019 3 0.028
system process GO:0003008 185 0.028
response to corticosteroid GO:0031960 1 0.028
mesodermal cell differentiation GO:0048333 21 0.028
negative regulation of mitotic cell cycle GO:0045930 11 0.028
cell cycle arrest GO:0007050 1 0.028
regulation of transferase activity GO:0051338 16 0.028
Mouse
positive regulation of secretion by cell GO:1903532 1 0.028
mediolateral intercalation GO:0060031 3 0.028
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.028
Human
ectoderm formation GO:0001705 2 0.028
erk1 and erk2 cascade GO:0070371 4 0.028
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
regulation of biosynthetic process GO:0009889 250 0.027
Human Mouse
forebrain regionalization GO:0021871 4 0.027
negative regulation of locomotion GO:0040013 18 0.027
Human
midbrain development GO:0030901 28 0.027
response to lipid GO:0033993 60 0.027
Human Mouse
cell fate commitment involved in pattern specification GO:0060581 6 0.027
rhombomere development GO:0021546 19 0.027
organelle fission GO:0048285 23 0.027
spemann organizer formation GO:0060061 10 0.027
embryonic heart tube morphogenesis GO:0003143 108 0.027
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.026
vasculature development GO:0001944 278 0.026
astrocyte differentiation GO:0048708 1 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
embryonic skeletal joint development GO:0072498 3 0.026
mesodermal cell migration GO:0008078 12 0.026
aging GO:0007568 2 0.026
cellular nitrogen compound biosynthetic process GO:0044271 218 0.026
Human
negative regulation of axon extension GO:0030517 7 0.025
posterior lateral line system development GO:0048915 46 0.025
negative regulation of developmental growth GO:0048640 9 0.025
Mouse
regulation of axon guidance GO:1902667 8 0.025
mesenchymal cell differentiation GO:0048762 87 0.025
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.025
cellular localization GO:0051641 97 0.025
Human
calcium ion transport into cytosol GO:0060402 3 0.025
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.025
cellular response to organic substance GO:0071310 105 0.025
Human Mouse
regulation of protein import into nucleus GO:0042306 2 0.025
regulation of neurogenesis GO:0050767 87 0.025
olfactory placode morphogenesis GO:0071699 7 0.024
negative regulation of reproductive process GO:2000242 3 0.024
regulation of cellular biosynthetic process GO:0031326 245 0.024
Human Mouse
behavior GO:0007610 74 0.024
positive regulation of jnk cascade GO:0046330 3 0.024
regulation of neuron projection development GO:0010975 40 0.024
endodermal cell fate specification GO:0001714 17 0.024
forebrain cell migration GO:0021885 1 0.024
negative regulation of cell division GO:0051782 4 0.024
regulation of localization GO:0032879 104 0.024
Human
negative regulation of biosynthetic process GO:0009890 55 0.023
Human
regulation of mesoderm development GO:2000380 11 0.023
regulation of behavior GO:0050795 24 0.023
negative regulation of chemotaxis GO:0050922 4 0.023
regulation of cell differentiation GO:0045595 142 0.023
Human Mouse
epiboly GO:0090504 41 0.023
neural nucleus development GO:0048857 15 0.023
negative regulation of neutrophil migration GO:1902623 3 0.023
defense response GO:0006952 47 0.022
negative regulation of jnk cascade GO:0046329 1 0.022
Mouse
macromolecule modification GO:0043412 111 0.022
Human Mouse
cell proliferation in midbrain GO:0033278 4 0.022
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.022
Mouse

sfrp1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.145
musculoskeletal system disease DOID:17 0 0.145
connective tissue disease DOID:65 0 0.145
bone disease DOID:0080001 0 0.035
large intestine cancer DOID:5672 0 0.029
gastrointestinal system cancer DOID:3119 0 0.029
intestinal cancer DOID:10155 0 0.029
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029
colon cancer DOID:219 0 0.028
colorectal cancer DOID:9256 0 0.028
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025