Danio rerio

0 known processes

sh3bp4a

SH3-domain binding protein 4a

(Aliases: sh3bp4)

sh3bp4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 181 0.276
sensory organ morphogenesis GO:0090596 200 0.157
organic substance biosynthetic process GO:1901576 289 0.149
embryonic organ development GO:0048568 381 0.144
specification of symmetry GO:0009799 204 0.138
amino acid transport GO:0006865 2 0.131
multicellular organism growth GO:0035264 4 0.099
sensory organ development GO:0007423 393 0.088
chordate embryonic development GO:0043009 271 0.085
regulation of multicellular organism growth GO:0040014 4 0.082
tube morphogenesis GO:0035239 349 0.080
aging GO:0007568 2 0.073
wound healing GO:0042060 90 0.072
cellular biosynthetic process GO:0044249 286 0.068
nucleobase containing compound metabolic process GO:0006139 274 0.067
Human
negative regulation of biological process GO:0048519 304 0.066
Human
oxoacid metabolic process GO:0043436 31 0.066
response to stress GO:0006950 263 0.065
cellular modified amino acid metabolic process GO:0006575 3 0.064
mesenchyme development GO:0060485 127 0.064
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.063
cellular amino acid metabolic process GO:0006520 7 0.062
generation of neurons GO:0048699 385 0.061
locomotion GO:0040011 313 0.060
response to chemical GO:0042221 320 0.059
Human
determination of left right symmetry GO:0007368 179 0.059
epithelial tube morphogenesis GO:0060562 148 0.058
transmembrane transport GO:0055085 120 0.057
amine metabolic process GO:0009308 2 0.056
organic acid metabolic process GO:0006082 31 0.055
response to abiotic stimulus GO:0009628 122 0.055
cellular component disassembly GO:0022411 1 0.054
cellular macromolecule biosynthetic process GO:0034645 224 0.052
heart development GO:0007507 313 0.052
rna biosynthetic process GO:0032774 181 0.050
gland development GO:0048732 143 0.049
maintenance of location GO:0051235 4 0.049
methylation GO:0032259 22 0.049
signal transduction GO:0007165 455 0.048
Human
developmental growth GO:0048589 166 0.046
adult behavior GO:0030534 2 0.046
positive regulation of catabolic process GO:0009896 4 0.046
Human
determination of bilateral symmetry GO:0009855 204 0.045
macromolecular complex disassembly GO:0032984 1 0.043
larval development GO:0002164 2 0.043
regulation of response to stimulus GO:0048583 269 0.042
Human
stem cell proliferation GO:0072089 4 0.042
biosynthetic process GO:0009058 294 0.042
macromolecule biosynthetic process GO:0009059 227 0.041
regulation of signaling GO:0023051 235 0.041
Human
axon ensheathment in central nervous system GO:0032291 2 0.040
positive regulation of cell cycle GO:0045787 3 0.040
cellular macromolecule metabolic process GO:0044260 391 0.040
brain development GO:0007420 293 0.039
ear development GO:0043583 127 0.038
regulation of epithelial cell proliferation GO:0050678 3 0.037
lipid storage GO:0019915 1 0.037
morphogenesis of an epithelium GO:0002009 333 0.037
cellular response to endogenous stimulus GO:0071495 68 0.037
Human
cellular amino acid biosynthetic process GO:0008652 2 0.036
regulation of reproductive process GO:2000241 4 0.036
cell morphogenesis involved in differentiation GO:0000904 195 0.035
positive regulation of biological process GO:0048518 253 0.035
Human
cell motility GO:0048870 244 0.035
multicellular organismal signaling GO:0035637 22 0.034
regulation of cell communication GO:0010646 232 0.034
Human
localization of cell GO:0051674 244 0.034
establishment of localization GO:0051234 244 0.033
cell migration GO:0016477 237 0.033
response to estrogen GO:0043627 27 0.033
neuroblast proliferation GO:0007405 2 0.032
extrinsic apoptotic signaling pathway GO:0097191 3 0.032
response to drug GO:0042493 3 0.032
protein dephosphorylation GO:0006470 3 0.032
cellular amine metabolic process GO:0044106 2 0.032
cellular component movement GO:0006928 335 0.031
nitrogen compound metabolic process GO:0006807 319 0.031
Human
cellular aromatic compound metabolic process GO:0006725 295 0.031
Human
regulation of signal transduction GO:0009966 225 0.031
Human
cellular biogenic amine metabolic process GO:0006576 2 0.030
regulation of dna replication GO:0006275 3 0.030
embryonic skeletal system development GO:0048706 97 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.030
Human
inner ear development GO:0048839 126 0.030
protein localization to nucleus GO:0034504 3 0.030
protein complex disassembly GO:0043241 1 0.030
single organism organelle organization GO:1902589 199 0.030
compound eye development GO:0048749 2 0.030
system process GO:0003008 185 0.029
heterocycle metabolic process GO:0046483 290 0.029
Human
transmission of nerve impulse GO:0019226 19 0.029
organonitrogen compound metabolic process GO:1901564 74 0.029
Human
sensory perception of mechanical stimulus GO:0050954 16 0.029
response to nutrient GO:0007584 3 0.029
hepaticobiliary system development GO:0061008 98 0.028
response to external stimulus GO:0009605 264 0.028
cell substrate adhesion GO:0031589 4 0.028
embryonic skeletal system morphogenesis GO:0048704 93 0.028
neural crest cell differentiation GO:0014033 72 0.028
embryo development ending in birth or egg hatching GO:0009792 271 0.027
negative regulation of epithelial cell proliferation GO:0050680 1 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.026
Human
camera type eye development GO:0043010 222 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
cell projection morphogenesis GO:0048858 244 0.026
response to lipid GO:0033993 60 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.026
regulation of cytoplasmic transport GO:1903649 4 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
small molecule metabolic process GO:0044281 77 0.025
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.025
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.025
epithelial tube formation GO:0072175 19 0.024
regulation of tube size GO:0035150 2 0.024
regulation of blood vessel size GO:0050880 2 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
Human
regulation of multicellular organismal process GO:0051239 277 0.024
eye development GO:0001654 277 0.024
superoxide metabolic process GO:0006801 2 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
regulation of biological quality GO:0065008 263 0.023
stem cell division GO:0017145 1 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
cellular response to external stimulus GO:0071496 2 0.023
homeostatic process GO:0042592 142 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.023
urogenital system development GO:0001655 97 0.022
lateral line system development GO:0048925 76 0.022
cellular protein modification process GO:0006464 100 0.022
regulation of protein localization to nucleus GO:1900180 2 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
central nervous system development GO:0007417 387 0.022
endosomal transport GO:0016197 2 0.022
rna metabolic process GO:0016070 219 0.022
epidermal cell differentiation GO:0009913 36 0.022
response to acid chemical GO:0001101 17 0.021
Human
protein metabolic process GO:0019538 183 0.021
gene expression GO:0010467 252 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
Human
skin development GO:0043588 54 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
Human
modification dependent protein catabolic process GO:0019941 3 0.021
fin regeneration GO:0031101 51 0.021
regulation of metabolic process GO:0019222 359 0.021
Human
nucleic acid templated transcription GO:0097659 181 0.020
membrane invagination GO:0010324 1 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
cellular response to nutrient levels GO:0031669 2 0.020
ameboidal type cell migration GO:0001667 143 0.020
transcription dna templated GO:0006351 181 0.020
neuron differentiation GO:0030182 353 0.020
response to organic cyclic compound GO:0014070 51 0.020
anion transport GO:0006820 38 0.020
negative regulation of metabolic process GO:0009892 86 0.020
Human
anterior posterior pattern specification GO:0009952 152 0.020
mesoderm development GO:0007498 88 0.020
lipid metabolic process GO:0006629 52 0.020
nucleic acid metabolic process GO:0090304 244 0.020
microtubule based process GO:0007017 60 0.019
neural crest cell development GO:0014032 62 0.019
regulation of cell cycle GO:0051726 52 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
inorganic ion transmembrane transport GO:0098660 57 0.019
cellular response to drug GO:0035690 1 0.019
response to endogenous stimulus GO:0009719 83 0.019
Human
response to organic substance GO:0010033 153 0.019
Human
regulation of cytokine production GO:0001817 3 0.019
cell morphogenesis GO:0000902 289 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
isoprenoid metabolic process GO:0006720 15 0.019
regionalization GO:0003002 274 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
pyruvate metabolic process GO:0006090 1 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
Human
appendage development GO:0048736 80 0.018
single organism nuclear import GO:1902593 3 0.018
cellular component assembly GO:0022607 170 0.018
regulation of biosynthetic process GO:0009889 250 0.018
response to alkaloid GO:0043279 2 0.018
epidermis development GO:0008544 48 0.018
positive regulation of reproductive process GO:2000243 2 0.018
erk1 and erk2 cascade GO:0070371 4 0.018
endoderm development GO:0007492 49 0.018
regulation of protein catabolic process GO:0042176 1 0.018
embryonic cranial skeleton morphogenesis GO:0048701 90 0.018
single organism localization GO:1902578 225 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
cellular response to growth factor stimulus GO:0071363 39 0.017
tube closure GO:0060606 1 0.017
anion transmembrane transport GO:0098656 12 0.017
single organism metabolic process GO:0044710 217 0.017
Human
regulation of rna biosynthetic process GO:2001141 213 0.017
somatic muscle development GO:0007525 4 0.017
vasculature development GO:0001944 278 0.017
tissue regeneration GO:0042246 74 0.017
response to ketone GO:1901654 1 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
positive regulation of cellular metabolic process GO:0031325 94 0.017
Human
multi organism process GO:0051704 134 0.017
cellular protein metabolic process GO:0044267 129 0.017
response to nicotine GO:0035094 2 0.017
organic anion transport GO:0015711 15 0.017
digestive system development GO:0055123 289 0.017
regulation of protein transport GO:0051223 3 0.017
meiotic nuclear division GO:0007126 4 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
growth GO:0040007 174 0.016
Human
regulation of primary metabolic process GO:0080090 311 0.016
Human
macromolecular complex subunit organization GO:0043933 74 0.016
cell matrix adhesion GO:0007160 4 0.016
cellular response to lipid GO:0071396 39 0.016
regulation of rna metabolic process GO:0051252 224 0.016
nuclear transport GO:0051169 4 0.016
lipid catabolic process GO:0016042 4 0.016
organelle organization GO:0006996 227 0.016
cellular response to organic substance GO:0071310 105 0.016
Human
positive regulation of cell division GO:0051781 2 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
positive regulation of metabolic process GO:0009893 108 0.015
Human
tube formation GO:0035148 25 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
regulation of cell death GO:0010941 103 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
mesenchymal cell development GO:0014031 78 0.015
response to oxygen levels GO:0070482 25 0.015
liver development GO:0001889 96 0.015
positive regulation of epithelial cell differentiation GO:0030858 2 0.015
regulation of developmental process GO:0050793 247 0.015
apoptotic process GO:0006915 116 0.015
response to carbohydrate GO:0009743 3 0.015
retina morphogenesis in camera type eye GO:0060042 79 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
immune system development GO:0002520 191 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
macromolecule modification GO:0043412 111 0.014
lipid biosynthetic process GO:0008610 22 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
regulation of membrane potential GO:0042391 23 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
cellular lipid metabolic process GO:0044255 36 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
protein acylation GO:0043543 3 0.014
peptide transport GO:0015833 1 0.014
transport GO:0006810 220 0.014
sex determination GO:0007530 1 0.014
phagocytosis GO:0006909 3 0.014
neuronal action potential GO:0019228 18 0.014
l amino acid transport GO:0015807 1 0.014
protein modification process GO:0036211 100 0.014
response to amino acid GO:0043200 2 0.013
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
protein import GO:0017038 3 0.013
cell proliferation GO:0008283 80 0.013
Human
negative regulation of biosynthetic process GO:0009890 55 0.013
neuron projection morphogenesis GO:0048812 161 0.013
regulation of cell motility GO:2000145 46 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
intracellular receptor signaling pathway GO:0030522 30 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
otic vesicle development GO:0071599 42 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
Human
regulation of stem cell differentiation GO:2000736 4 0.013
stem cell development GO:0048864 82 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
Human
positive regulation of cell adhesion GO:0045785 1 0.013
primary neural tube formation GO:0014020 1 0.013
negative regulation of dna replication GO:0008156 2 0.012
protein polyubiquitination GO:0000209 4 0.012
cytoskeleton organization GO:0007010 96 0.012
actin filament based movement GO:0030048 1 0.012
regulation of transporter activity GO:0032409 2 0.012
myeloid cell development GO:0061515 32 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
regeneration GO:0031099 91 0.012
establishment of spindle localization GO:0051293 12 0.012
stem cell maintenance GO:0019827 4 0.012
nuclear import GO:0051170 3 0.012
regulation of metal ion transport GO:0010959 4 0.012
positive regulation of secretion GO:0051047 1 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
protein acetylation GO:0006473 2 0.012
regulation of localization GO:0032879 104 0.012
axonogenesis GO:0007409 152 0.012
regulation of gene expression GO:0010468 265 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
regulation of cell activation GO:0050865 1 0.012
cellular protein complex disassembly GO:0043624 1 0.012
establishment of mitotic spindle localization GO:0040001 12 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
cellular ketone metabolic process GO:0042180 11 0.012
cell projection organization GO:0030030 284 0.012
cell substrate junction assembly GO:0007044 2 0.012
regulation of cell migration GO:0030334 40 0.012
cellular component biogenesis GO:0044085 178 0.012
cellular response to oxygen levels GO:0071453 1 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
muscle cell differentiation GO:0042692 139 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
programmed cell death GO:0012501 119 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
Human
circulatory system process GO:0003013 87 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
Human
lytic vacuole organization GO:0080171 1 0.011
immunoglobulin mediated immune response GO:0016064 3 0.011
protein targeting to nucleus GO:0044744 3 0.011
cell cycle GO:0007049 93 0.011
response to biotic stimulus GO:0009607 97 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.011
glycerophospholipid biosynthetic process GO:0046474 1 0.011
embryonic viscerocranium morphogenesis GO:0048703 52 0.011
positive regulation of cellular process GO:0048522 201 0.011
Human
regulation of cellular component movement GO:0051270 55 0.011
organelle assembly GO:0070925 110 0.011
mononuclear cell proliferation GO:0032943 1 0.011
death GO:0016265 121 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
dna templated transcription initiation GO:0006352 1 0.011
skeletal system morphogenesis GO:0048705 102 0.011
apoptotic signaling pathway GO:0097190 23 0.011
response to uv GO:0009411 3 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
otic vesicle morphogenesis GO:0071600 34 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.010
phosphorylation GO:0016310 69 0.010
cell death GO:0008219 121 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
negative regulation of cellular process GO:0048523 283 0.010
Human
negative regulation of cell motility GO:2000146 17 0.010
gtp metabolic process GO:0046039 4 0.010
Human
regulation of skeletal muscle tissue development GO:0048641 4 0.010
negative regulation of gene expression GO:0010629 65 0.010
cellular protein catabolic process GO:0044257 4 0.010
cellular component morphogenesis GO:0032989 336 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010
cell part morphogenesis GO:0032990 246 0.010

sh3bp4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.125
cardiovascular system disease DOID:1287 0 0.043
endocrine system disease DOID:28 0 0.036
nervous system disease DOID:863 0 0.024