Danio rerio

0 known processes

shfm1

split hand/foot malformation (ectrodactyly) type 1

(Aliases: zgc:56203,zgc:85901,Shfdg1,wu:fb55c02)

shfm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.475
Worm
regulation of meiotic cell cycle GO:0051445 1 0.373
meiotic nuclear division GO:0007126 4 0.345
embryo development ending in birth or egg hatching GO:0009792 271 0.224
Worm
lipid storage GO:0019915 1 0.222
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.196
cellular component movement GO:0006928 335 0.163
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.157
mitotic dna integrity checkpoint GO:0044774 4 0.119
aging GO:0007568 2 0.105
locomotion GO:0040011 313 0.102
maintenance of location GO:0051235 4 0.094
cellular protein catabolic process GO:0044257 4 0.093
meiotic chromosome segregation GO:0045132 3 0.080
multicellular organism growth GO:0035264 4 0.077
Worm
neuron development GO:0048666 262 0.077
regulation of embryonic development GO:0045995 47 0.074
localization of cell GO:0051674 244 0.074
rna biosynthetic process GO:0032774 181 0.073
single fertilization GO:0007338 3 0.070
pronuclear migration GO:0035046 1 0.070
cell morphogenesis GO:0000902 289 0.070
organelle fission GO:0048285 23 0.067
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.066
positive regulation of biological process GO:0048518 253 0.063
Worm
modification dependent macromolecule catabolic process GO:0043632 3 0.061
growth GO:0040007 174 0.059
Worm
reproduction GO:0000003 40 0.058
Worm
cell migration GO:0016477 237 0.057
cell motility GO:0048870 244 0.057
regionalization GO:0003002 274 0.056
meiotic cell cycle process GO:1903046 3 0.056
proteasomal protein catabolic process GO:0010498 2 0.056
regulation of macromolecule metabolic process GO:0060255 317 0.053
Worm
fertilization GO:0009566 3 0.050
regulation of cell cycle GO:0051726 52 0.050
organelle organization GO:0006996 227 0.049
regulation of mrna splicing via spliceosome GO:0048024 3 0.049
regulation of chromosome segregation GO:0051983 1 0.049
establishment of localization GO:0051234 244 0.048
Worm
cell projection morphogenesis GO:0048858 244 0.047
nitrogen compound metabolic process GO:0006807 319 0.045
regulation of gene expression GO:0010468 265 0.045
regulation of multicellular organism growth GO:0040014 4 0.045
Worm
chordate embryonic development GO:0043009 271 0.044
organic cyclic compound metabolic process GO:1901360 301 0.044
cellular protein metabolic process GO:0044267 129 0.042
Worm
tube morphogenesis GO:0035239 349 0.042
protein metabolic process GO:0019538 183 0.042
Worm
cellular macromolecule metabolic process GO:0044260 391 0.042
Worm
modification dependent protein catabolic process GO:0019941 3 0.041
gland development GO:0048732 143 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.039
cell division GO:0051301 20 0.039
macromolecule modification GO:0043412 111 0.038
Worm
meiosis ii GO:0007135 1 0.035
chromosome organization involved in meiosis GO:0070192 1 0.035
organism emergence from protective structure GO:0071684 4 0.035
neuron differentiation GO:0030182 353 0.034
multi organism process GO:0051704 134 0.034
Worm
neuron projection development GO:0031175 180 0.033
somitogenesis GO:0001756 87 0.033
cellular component assembly GO:0022607 170 0.032
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
generation of neurons GO:0048699 385 0.031
response to drug GO:0042493 3 0.031
cellular component morphogenesis GO:0032989 336 0.031
single organism reproductive process GO:0044702 40 0.031
Worm
mitotic g2 dna damage checkpoint GO:0007095 3 0.030
regulation of cellular component organization GO:0051128 86 0.030
single organism organelle organization GO:1902589 199 0.029
cell projection organization GO:0030030 284 0.028
regulation of cellular biosynthetic process GO:0031326 245 0.028
small molecule metabolic process GO:0044281 77 0.028
anterior posterior pattern specification GO:0009952 152 0.028
microtubule based movement GO:0007018 33 0.028
heterocycle metabolic process GO:0046483 290 0.027
ubiquitin dependent protein catabolic process GO:0006511 3 0.027
regulation of biological quality GO:0065008 263 0.027
regulation of synapse assembly GO:0051963 3 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.027
Worm
cellular response to stress GO:0033554 62 0.026
catabolic process GO:0009056 32 0.026
cell part morphogenesis GO:0032990 246 0.026
establishment of protein localization to organelle GO:0072594 4 0.026
regulation of biosynthetic process GO:0009889 250 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.025
development of primary female sexual characteristics GO:0046545 4 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
mitotic cell cycle process GO:1903047 48 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
nucleic acid templated transcription GO:0097659 181 0.024
mitotic nuclear division GO:0007067 18 0.024
protein localization to nucleus GO:0034504 3 0.023
mitochondrion organization GO:0007005 4 0.023
regulation of metabolic process GO:0019222 359 0.023
Worm
mitotic g2 m transition checkpoint GO:0044818 3 0.022
cell proliferation GO:0008283 80 0.022
double strand break repair via homologous recombination GO:0000724 1 0.022
ribonucleoside monophosphate catabolic process GO:0009158 4 0.022
cell cycle process GO:0022402 53 0.021
cellular component biogenesis GO:0044085 178 0.021
developmental growth GO:0048589 166 0.021
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
ameboidal type cell migration GO:0001667 143 0.020
mitotic dna damage checkpoint GO:0044773 4 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
stem cell differentiation GO:0048863 117 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
cellular protein modification process GO:0006464 100 0.020
Worm
stem cell maintenance GO:0019827 4 0.019
gene expression GO:0010467 252 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
heart development GO:0007507 313 0.019
digestive tract development GO:0048565 265 0.019
nuclear division GO:0000280 23 0.019
nucleobase containing small molecule metabolic process GO:0055086 32 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
hatching GO:0035188 4 0.019
embryonic organ development GO:0048568 381 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
response to abiotic stimulus GO:0009628 122 0.018
liver development GO:0001889 96 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
spliceosomal snrnp assembly GO:0000387 2 0.018
developmental process involved in reproduction GO:0003006 27 0.017
Worm
response to chemical GO:0042221 320 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
somite development GO:0061053 96 0.017
response to stress GO:0006950 263 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
dna templated transcription initiation GO:0006352 1 0.017
regulation of organelle organization GO:0033043 29 0.017
regulation of rna biosynthetic process GO:2001141 213 0.016
positive regulation of transport GO:0051050 2 0.016
stem cell proliferation GO:0072089 4 0.016
regulation of synapse organization GO:0050807 3 0.016
positive regulation of cellular process GO:0048522 201 0.016
Worm
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
cellular protein complex assembly GO:0043623 19 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
regulation of oocyte development GO:0060281 3 0.015
mitotic sister chromatid segregation GO:0000070 6 0.015
actin cytoskeleton organization GO:0030036 63 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
Worm
regulation of establishment of protein localization GO:0070201 4 0.015
negative regulation of cellular process GO:0048523 283 0.015
regulation of binding GO:0051098 3 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.015
Worm
aromatic compound biosynthetic process GO:0019438 217 0.015
regulation of programmed cell death GO:0043067 101 0.015
nucleic acid metabolic process GO:0090304 244 0.014
g2 dna damage checkpoint GO:0031572 3 0.014
single organism nuclear import GO:1902593 3 0.014
locomotor rhythm GO:0045475 3 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
Worm
gamete generation GO:0007276 33 0.014
Worm
cellular biosynthetic process GO:0044249 286 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
regulation of cell proliferation GO:0042127 37 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.014
hepaticobiliary system development GO:0061008 98 0.014
regulation of transcription dna templated GO:0006355 213 0.014
cell cycle GO:0007049 93 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
positive regulation of rna biosynthetic process GO:1902680 57 0.014
regulation of primary metabolic process GO:0080090 311 0.014
Worm
negative regulation of cytoplasmic transport GO:1903650 2 0.013
transcription dna templated GO:0006351 181 0.013
multicellular organismal macromolecule metabolic process GO:0044259 2 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
proteolysis GO:0006508 38 0.013
nuclear migration GO:0007097 3 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
regulation of protein complex assembly GO:0043254 3 0.013
nuclear import GO:0051170 3 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
transport GO:0006810 220 0.013
Worm
system process GO:0003008 185 0.013
Worm
regulation of cell communication GO:0010646 232 0.013
mitotic cell cycle GO:0000278 64 0.013
double strand break repair GO:0006302 3 0.012
multi organism reproductive process GO:0044703 36 0.012
Worm
neuroblast proliferation GO:0007405 2 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
positive regulation of catabolic process GO:0009896 4 0.012
actin mediated cell contraction GO:0070252 1 0.012
negative regulation of biological process GO:0048519 304 0.012
negative regulation of protein transport GO:0051224 3 0.012
protein import GO:0017038 3 0.012
protein import into nucleus GO:0006606 3 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
negative regulation of immune response GO:0050777 2 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
response to endogenous stimulus GO:0009719 83 0.012
segmentation GO:0035282 97 0.011
atp catabolic process GO:0006200 4 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
muscle structure development GO:0061061 196 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
protein polyubiquitination GO:0000209 4 0.011
reproductive process GO:0022414 40 0.011
Worm
single organism metabolic process GO:0044710 217 0.011
macromolecule localization GO:0033036 54 0.011
regulation of mitotic cell cycle embryonic GO:0009794 2 0.011
cellular catabolic process GO:0044248 27 0.011
developmental programmed cell death GO:0010623 4 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
biosynthetic process GO:0009058 294 0.011
positive regulation of gene expression GO:0010628 71 0.011
regulation of cell cycle process GO:0010564 20 0.011
axis specification GO:0009798 43 0.011
rna metabolic process GO:0016070 219 0.011
cellular response to organic substance GO:0071310 105 0.011
positive regulation of dna templated transcription elongation GO:0032786 1 0.011
positive regulation of wound healing GO:0090303 1 0.011
regulation of rna metabolic process GO:0051252 224 0.011
death GO:0016265 121 0.010
protein secretion GO:0009306 1 0.010
regulation of inflammatory response GO:0050727 2 0.010
mesenchyme development GO:0060485 127 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
autophagy GO:0006914 4 0.010
regulation of nuclear division GO:0051783 9 0.010
regulation of protein transport GO:0051223 3 0.010
nuclear transport GO:0051169 4 0.010

shfm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.019
disease of anatomical entity DOID:7 0 0.018