Danio rerio

41 known processes

six3b

sine oculis homeobox homolog 3b

(Aliases: six3.2,six6,cb347,SIX3)

six3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
head development GO:0060322 303 0.992
neuron differentiation GO:0030182 353 0.984
Zebrafish Mouse Fly
retina development in camera type eye GO:0060041 146 0.983
Mouse
gland development GO:0048732 143 0.981
Zebrafish Mouse
regulation of multicellular organismal development GO:2000026 223 0.981
Zebrafish Mouse
central nervous system development GO:0007417 387 0.979
morphogenesis of an epithelium GO:0002009 333 0.978
hindbrain development GO:0030902 91 0.974
eye morphogenesis GO:0048592 144 0.971
camera type eye development GO:0043010 222 0.970
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.969
Zebrafish Mouse
brain development GO:0007420 293 0.963
forebrain development GO:0030900 96 0.961
Zebrafish Mouse
generation of neurons GO:0048699 385 0.957
Zebrafish Mouse Fly
transcription dna templated GO:0006351 181 0.954
Zebrafish Mouse
neuron projection development GO:0031175 180 0.947
Fly
eye development GO:0001654 277 0.945
retina morphogenesis in camera type eye GO:0060042 79 0.938
regulation of rna biosynthetic process GO:2001141 213 0.936
Zebrafish Mouse
oligodendrocyte cell fate specification GO:0021778 4 0.919
central nervous system neuron differentiation GO:0021953 74 0.909
neuron fate specification GO:0048665 20 0.899
ventral midline development GO:0007418 13 0.897
camera type eye morphogenesis GO:0048593 108 0.895
cell fate commitment GO:0045165 99 0.890
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.888
Zebrafish Mouse
embryonic heart tube development GO:0035050 133 0.883
regulation of cellular metabolic process GO:0031323 320 0.881
Zebrafish Mouse
cell morphogenesis GO:0000902 289 0.877
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.877
Fly
cellular component morphogenesis GO:0032989 336 0.875
Fly
neural crest cell development GO:0014032 62 0.875
nucleobase containing compound biosynthetic process GO:0034654 205 0.872
Zebrafish Mouse
mesenchyme development GO:0060485 127 0.857
eye photoreceptor cell development GO:0042462 30 0.855
regulation of rna metabolic process GO:0051252 224 0.852
Zebrafish Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.844
regulation of macromolecule metabolic process GO:0060255 317 0.834
Zebrafish Mouse
nucleic acid metabolic process GO:0090304 244 0.828
Zebrafish Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.823
Zebrafish Mouse
cranial nerve development GO:0021545 42 0.820
sensory organ morphogenesis GO:0090596 200 0.815
regulation of primary metabolic process GO:0080090 311 0.804
Zebrafish Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.801
Zebrafish Mouse
cell surface receptor signaling pathway GO:0007166 325 0.795
Mouse
glial cell fate specification GO:0021780 4 0.789
forebrain neuron fate commitment GO:0021877 1 0.778
heart development GO:0007507 313 0.755
regulation of cell differentiation GO:0045595 142 0.745
Zebrafish Mouse
regulation of response to stimulus GO:0048583 269 0.743
Mouse
digestive tract development GO:0048565 265 0.740
Zebrafish
striated muscle tissue development GO:0014706 110 0.738
Zebrafish
forebrain regionalization GO:0021871 4 0.736
Mouse
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.726
forebrain cell migration GO:0021885 1 0.725
regulation of developmental process GO:0050793 247 0.708
Zebrafish Mouse
neuron fate commitment GO:0048663 26 0.701
brain morphogenesis GO:0048854 18 0.690
axon development GO:0061564 166 0.689
organelle localization GO:0051640 49 0.688
neural retina development GO:0003407 49 0.688
Mouse
cell part morphogenesis GO:0032990 246 0.676
Fly
anterior posterior pattern specification GO:0009952 152 0.673
Mouse
chordate embryonic development GO:0043009 271 0.671
regulation of transcription dna templated GO:0006355 213 0.670
Zebrafish Mouse
regionalization GO:0003002 274 0.667
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.667
Zebrafish Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.652
Zebrafish Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.639
Mouse
signal transduction GO:0007165 455 0.634
Mouse
embryonic organ development GO:0048568 381 0.627
positive regulation of biological process GO:0048518 253 0.620
Mouse
forebrain dorsal ventral pattern formation GO:0021798 1 0.619
nucleic acid templated transcription GO:0097659 181 0.619
Zebrafish Mouse
ventral spinal cord interneuron specification GO:0021521 3 0.619
ventral spinal cord development GO:0021517 35 0.610
rna metabolic process GO:0016070 219 0.609
Zebrafish Mouse
regulation of multicellular organismal process GO:0051239 277 0.604
Zebrafish Mouse
axon guidance GO:0007411 86 0.601
adenohypophysis development GO:0021984 15 0.600
Zebrafish
specification of symmetry GO:0009799 204 0.597
pancreatic d cell differentiation GO:0003311 2 0.591
sensory organ development GO:0007423 393 0.589
embryonic eye morphogenesis GO:0048048 30 0.587
macromolecule biosynthetic process GO:0009059 227 0.586
Zebrafish Mouse
positive regulation of biosynthetic process GO:0009891 68 0.583
Mouse
growth GO:0040007 174 0.583
regulation of metabolic process GO:0019222 359 0.583
Zebrafish Mouse
regulation of signal transduction GO:0009966 225 0.582
Mouse
central nervous system myelin formation GO:0032289 1 0.580
neuron development GO:0048666 262 0.579
Zebrafish Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.572
Zebrafish Mouse
muscle tissue development GO:0060537 110 0.565
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.564
Zebrafish Mouse
cell projection morphogenesis GO:0048858 244 0.551
Fly
negative regulation of transcription dna templated GO:0045892 45 0.546
Mouse
heterocycle biosynthetic process GO:0018130 215 0.543
Zebrafish Mouse
glial cell differentiation GO:0010001 42 0.542
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.507
Mouse
neuron projection morphogenesis GO:0048812 161 0.507
Fly
forebrain neuron development GO:0021884 7 0.503
heart morphogenesis GO:0003007 156 0.501
pancreas development GO:0031016 84 0.501
eye photoreceptor cell differentiation GO:0001754 45 0.492
Fly
embryonic camera type eye morphogenesis GO:0048596 19 0.486
cell morphogenesis involved in differentiation GO:0000904 195 0.471
Fly
retinal pigment epithelium development GO:0003406 8 0.469
retina layer formation GO:0010842 24 0.468
digestive system development GO:0055123 289 0.460
Zebrafish
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.459
retinal cell programmed cell death GO:0046666 2 0.457
myelination GO:0042552 18 0.455
embryonic camera type eye development GO:0031076 29 0.452
regulation of biological quality GO:0065008 263 0.451
regulation of nervous system development GO:0051960 90 0.433
Zebrafish Mouse
positive regulation of rna metabolic process GO:0051254 59 0.426
Mouse
photoreceptor cell fate commitment GO:0046552 1 0.424
regulation of epithelial cell proliferation GO:0050678 3 0.419
cellular aromatic compound metabolic process GO:0006725 295 0.417
Zebrafish Mouse
spinal cord development GO:0021510 46 0.416
central nervous system myelination GO:0022010 2 0.416
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.408
Mouse
regulation of cellular component organization GO:0051128 86 0.408
neural crest cell differentiation GO:0014033 72 0.405
heart looping GO:0001947 94 0.405
cell fate specification GO:0001708 68 0.399
diencephalon development GO:0021536 58 0.392
Zebrafish Mouse
ensheathment of neurons GO:0007272 18 0.389
nerve development GO:0021675 45 0.387
pituitary gland development GO:0021983 16 0.384
Zebrafish Mouse
gastrulation GO:0007369 208 0.382
endocrine system development GO:0035270 65 0.373
Zebrafish Mouse
glial cell fate commitment GO:0021781 6 0.365
diencephalon morphogenesis GO:0048852 5 0.361
regulation of nucleoside metabolic process GO:0009118 2 0.357
digestive tract morphogenesis GO:0048546 231 0.356
epithelial cell differentiation GO:0030855 116 0.354
Mouse
cell projection organization GO:0030030 284 0.354
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.341
neuron projection guidance GO:0097485 86 0.340
embryonic viscerocranium morphogenesis GO:0048703 52 0.337
positive regulation of cellular process GO:0048522 201 0.334
Mouse
chemotaxis GO:0006935 104 0.334
single organism organelle organization GO:1902589 199 0.333
heterocycle metabolic process GO:0046483 290 0.325
Zebrafish Mouse
gene expression GO:0010467 252 0.322
Zebrafish Mouse
cellular biosynthetic process GO:0044249 286 0.322
Zebrafish Mouse
positive regulation of metabolic process GO:0009893 108 0.313
Mouse
motor neuron axon guidance GO:0008045 23 0.307
segmentation GO:0035282 97 0.303
positive regulation of gene expression GO:0010628 71 0.302
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.301
Zebrafish Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.300
Mouse
organ formation GO:0048645 17 0.300
collateral sprouting of intact axon in response to injury GO:0048673 2 0.285
photoreceptor cell differentiation GO:0046530 55 0.284
Fly
forebrain morphogenesis GO:0048853 6 0.283
outflow tract morphogenesis GO:0003151 1 0.281
locomotion GO:0040011 313 0.280
Mouse Worm
rna biosynthetic process GO:0032774 181 0.277
Zebrafish Mouse
mesenchymal cell development GO:0014031 78 0.273
olfactory bulb development GO:0021772 4 0.272
positive regulation of rna biosynthetic process GO:1902680 57 0.271
Mouse
positive regulation of cell fate commitment GO:0010455 1 0.271
regulation of biosynthetic process GO:0009889 250 0.270
Zebrafish Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.269
Zebrafish Mouse
regulation of mechanoreceptor differentiation GO:0045631 1 0.268
Zebrafish
regulation of synapse organization GO:0050807 3 0.267
neuronal action potential GO:0019228 18 0.263
cellular macromolecule metabolic process GO:0044260 391 0.260
Zebrafish Mouse
nitrogen compound metabolic process GO:0006807 319 0.257
Zebrafish Mouse
negative regulation of rna metabolic process GO:0051253 48 0.257
Mouse
developmental process involved in reproduction GO:0003006 27 0.256
peripheral nervous system development GO:0007422 55 0.256
Zebrafish
neuron fate determination GO:0048664 2 0.253
regulation of cell death GO:0010941 103 0.253
central nervous system neuron development GO:0021954 29 0.252
vesicle localization GO:0051648 27 0.251
cellular component movement GO:0006928 335 0.246
Mouse
determination of left right symmetry GO:0007368 179 0.245
negative regulation of cellular biosynthetic process GO:0031327 55 0.244
Mouse
response to external stimulus GO:0009605 264 0.242
photoreceptor cell development GO:0042461 40 0.240
camera type eye photoreceptor cell differentiation GO:0060219 19 0.237
cellular nitrogen compound metabolic process GO:0034641 290 0.234
Zebrafish Mouse
negative regulation of neuron projection regeneration GO:0070571 4 0.233
regulation of gene expression GO:0010468 265 0.231
Zebrafish Mouse
axonal fasciculation GO:0007413 11 0.229
response to chemical GO:0042221 320 0.227
negative regulation of multicellular organismal process GO:0051241 69 0.226
Mouse
telencephalon development GO:0021537 14 0.224
Mouse
angiogenesis GO:0001525 158 0.224
cranial ganglion development GO:0061550 3 0.223
glial cell migration GO:0008347 3 0.219
positive regulation of catabolic process GO:0009896 4 0.214
regulation of apoptotic process GO:0042981 98 0.214
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.206
positive regulation of cellular biosynthetic process GO:0031328 68 0.205
Mouse
positive regulation of neuron migration GO:2001224 2 0.201
regulation of neuron differentiation GO:0045664 56 0.201
Zebrafish Mouse
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.199
chemosensory behavior GO:0007635 1 0.197
ventral spinal cord interneuron differentiation GO:0021514 12 0.195
regulation of signaling GO:0023051 235 0.194
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.193
Worm
skeletal muscle organ development GO:0060538 78 0.191
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.190
Zebrafish Mouse
regulation of neurogenesis GO:0050767 87 0.188
Zebrafish Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.188
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.187
oligodendrocyte differentiation GO:0048709 23 0.186
cell differentiation in spinal cord GO:0021515 40 0.186
olfactory lobe development GO:0021988 4 0.185
regulation of programmed cell death GO:0043067 101 0.185
negative regulation of nervous system development GO:0051961 22 0.184
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.182
Mouse
neural crest cell migration GO:0001755 42 0.181
central nervous system projection neuron axonogenesis GO:0021952 15 0.180
cellular component biogenesis GO:0044085 178 0.177
positive regulation of nucleic acid templated transcription GO:1903508 57 0.176
Mouse
floor plate development GO:0033504 15 0.176
cellular nitrogen compound biosynthetic process GO:0044271 218 0.175
Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.172
Zebrafish Mouse
embryonic organ morphogenesis GO:0048562 274 0.171
blood vessel development GO:0001568 246 0.170
mitotic cell cycle GO:0000278 64 0.167
dendrite development GO:0016358 9 0.166
Fly
forebrain midbrain boundary formation GO:0021905 1 0.165
negative regulation of signal transduction GO:0009968 94 0.162
Mouse
regulation of cell development GO:0060284 100 0.161
Zebrafish Mouse
cell death GO:0008219 121 0.161
Mouse
localization of cell GO:0051674 244 0.160
Mouse
spinal cord motor neuron cell fate specification GO:0021520 8 0.156
positive regulation of transcription dna templated GO:0045893 57 0.155
Mouse
determination of bilateral symmetry GO:0009855 204 0.154
appendage development GO:0048736 80 0.150
central nervous system neuron axonogenesis GO:0021955 18 0.148
glial cell development GO:0021782 20 0.146
pigmentation GO:0043473 85 0.144
positive regulation of nervous system development GO:0051962 25 0.142
axon ensheathment GO:0008366 18 0.140
intracellular signal transduction GO:0035556 85 0.140
negative regulation of neuron differentiation GO:0045665 10 0.139
Mouse
cell migration GO:0016477 237 0.138
Mouse
establishment of localization GO:0051234 244 0.138
Mouse
negative regulation of cellular process GO:0048523 283 0.138
Mouse
somite development GO:0061053 96 0.136
blood vessel morphogenesis GO:0048514 216 0.134
pancreatic a cell development GO:0003322 2 0.134
oligodendrocyte cell fate commitment GO:0021779 5 0.132
axonogenesis GO:0007409 152 0.132
locomotory behavior GO:0007626 34 0.132
muscle cell differentiation GO:0042692 139 0.130
Zebrafish
transmission of nerve impulse GO:0019226 19 0.129
cellular response to prostaglandin stimulus GO:0071379 3 0.127
cell proliferation GO:0008283 80 0.126
Zebrafish Mouse
iris morphogenesis GO:0061072 1 0.123
auditory receptor cell fate commitment GO:0009912 4 0.123
wnt signaling pathway GO:0016055 80 0.121
Mouse
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.120
tube morphogenesis GO:0035239 349 0.120
bmp signaling pathway GO:0030509 52 0.119
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.119
Mouse
posterior lateral line system development GO:0048915 46 0.117
regulation of neurological system process GO:0031644 2 0.117
pigment cell differentiation GO:0050931 38 0.117
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.117
Mouse
cardiac muscle tissue development GO:0048738 48 0.114
negative regulation of cellular metabolic process GO:0031324 77 0.114
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.114
epidermal cell fate specification GO:0009957 4 0.114
positive regulation of cell cycle GO:0045787 3 0.113
ventral spinal cord interneuron fate commitment GO:0060579 3 0.112
facial nucleus development GO:0021754 7 0.111
notch signaling pathway GO:0007219 35 0.110
regulation of stem cell proliferation GO:0072091 2 0.110
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.109
Zebrafish Mouse
cell motility GO:0048870 244 0.107
Mouse
convergent extension GO:0060026 118 0.106
positive regulation of epithelial cell differentiation GO:0030858 2 0.103
mesenchymal cell differentiation GO:0048762 87 0.103
metencephalon development GO:0022037 27 0.102
forebrain anterior posterior pattern specification GO:0021797 3 0.102
Mouse
neuron recognition GO:0008038 18 0.102
positive regulation of macromolecule metabolic process GO:0010604 93 0.100
Mouse
response to organic substance GO:0010033 153 0.099
epidermis development GO:0008544 48 0.098
regulation of synapse assembly GO:0051963 3 0.097
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.096
hematopoietic or lymphoid organ development GO:0048534 191 0.094
lateral line nerve glial cell differentiation GO:0048895 6 0.094
neural tube development GO:0021915 62 0.093
multi organism process GO:0051704 134 0.092
negative regulation of biosynthetic process GO:0009890 55 0.092
Mouse
transport GO:0006810 220 0.091
Mouse
regulation of neuron migration GO:2001222 2 0.091
positive regulation of cell communication GO:0010647 56 0.090
multicellular organismal signaling GO:0035637 22 0.090
determination of left right asymmetry in nervous system GO:0035545 4 0.089
developmental growth GO:0048589 166 0.088
embryonic epithelial tube formation GO:0001838 17 0.088
organelle organization GO:0006996 227 0.087
regulation of organ morphogenesis GO:2000027 35 0.087
endodermal cell fate commitment GO:0001711 18 0.087
epithelial tube morphogenesis GO:0060562 148 0.086
reflex GO:0060004 2 0.086
fin development GO:0033333 77 0.085
cellular response to chemical stimulus GO:0070887 157 0.085
negative regulation of developmental process GO:0051093 65 0.085
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.085
pronephric glomerulus development GO:0039021 13 0.084
ameboidal type cell migration GO:0001667 143 0.083
lens morphogenesis in camera type eye GO:0002089 7 0.082
Mouse
regulation of multicellular organism growth GO:0040014 4 0.081
reproductive process GO:0022414 40 0.081
negative regulation of axon regeneration GO:0048681 4 0.081
enzyme linked receptor protein signaling pathway GO:0007167 106 0.078
negative regulation of biological process GO:0048519 304 0.078
Mouse
retinal ganglion cell axon guidance GO:0031290 35 0.077
startle response GO:0001964 4 0.077
cellular component assembly GO:0022607 170 0.077
melanocyte differentiation GO:0030318 26 0.077
endocardium formation GO:0060214 1 0.076
cellular response to fatty acid GO:0071398 3 0.075
cellular localization GO:0051641 97 0.074
Mouse
regulation of cell communication GO:0010646 232 0.074
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.074
Mouse
abducens nucleus development GO:0021742 2 0.074
negative regulation of collateral sprouting GO:0048671 2 0.073
negative regulation of axon extension GO:0030517 7 0.072
anterior posterior axon guidance GO:0033564 5 0.072
system process GO:0003008 185 0.072
action potential GO:0001508 19 0.069
death GO:0016265 121 0.069
Mouse
pectoral fin development GO:0033339 50 0.069
guanosine containing compound catabolic process GO:1901069 2 0.067
retinal cone cell development GO:0046549 8 0.066
neuroblast proliferation GO:0007405 2 0.066
Mouse
endoderm formation GO:0001706 29 0.066
endocrine pancreas development GO:0031018 27 0.066
negative regulation of metabolic process GO:0009892 86 0.065
Mouse
pronephros development GO:0048793 69 0.065
Zebrafish
negative regulation of protein phosphorylation GO:0001933 4 0.065
cellular response to organic substance GO:0071310 105 0.063
cell proliferation in forebrain GO:0021846 3 0.063
Mouse
regulation of intracellular signal transduction GO:1902531 57 0.063
neuron migration GO:0001764 22 0.062
determination of pancreatic left right asymmetry GO:0035469 11 0.062
urogenital system development GO:0001655 97 0.061
Zebrafish
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.061
Mouse
mitotic cell cycle process GO:1903047 48 0.060
establishment of organelle localization GO:0051656 45 0.060
regulation of myelination GO:0031641 1 0.060
cardiocyte differentiation GO:0035051 44 0.058
cell substrate adhesion GO:0031589 4 0.058
hatching gland development GO:0048785 3 0.058
primary neural tube formation GO:0014020 1 0.058
spinal cord oligodendrocyte cell differentiation GO:0021529 5 0.058
determination of left right asymmetry in diencephalon GO:0035462 4 0.058
developmental growth involved in morphogenesis GO:0060560 86 0.057
mechanosensory lateral line system development GO:0048881 49 0.056
negative regulation of epithelial cell proliferation GO:0050680 1 0.055
negative regulation of cell communication GO:0010648 96 0.055
Mouse
inner ear receptor cell fate commitment GO:0060120 4 0.055
gliogenesis GO:0042063 45 0.055
axon extension GO:0048675 45 0.054
phagocytosis GO:0006909 3 0.054
cilium morphogenesis GO:0060271 85 0.054
ectodermal placode formation GO:0060788 26 0.054
axis specification GO:0009798 43 0.053
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.053
Mouse
immune system process GO:0002376 241 0.053
programmed cell death GO:0012501 119 0.053
Mouse
myeloid cell homeostasis GO:0002262 56 0.053
regulation of cardiac chamber morphogenesis GO:1901219 2 0.052
developmental cell growth GO:0048588 52 0.052
compound eye development GO:0048749 2 0.052
Fly
lipid storage GO:0019915 1 0.051
axon ensheathment in central nervous system GO:0032291 2 0.051
pectoral fin morphogenesis GO:0035138 29 0.051
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.050
multicellular organism growth GO:0035264 4 0.050
tube formation GO:0035148 25 0.050
dendrite morphogenesis GO:0048813 5 0.050
Fly
anterior commissure morphogenesis GO:0021960 3 0.050
muscle organ development GO:0007517 101 0.049
Zebrafish
endocardium morphogenesis GO:0003160 4 0.049
positive regulation of transport GO:0051050 2 0.049
muscle structure development GO:0061061 196 0.049
Zebrafish
positive regulation of cellular catabolic process GO:0031331 3 0.049
cell fate specification involved in pattern specification GO:0060573 3 0.049
meiotic cell cycle process GO:1903046 3 0.048
retinal cone cell differentiation GO:0042670 12 0.048
homeostatic process GO:0042592 142 0.048
negative regulation of gene expression GO:0010629 65 0.048
Mouse
neurological system process GO:0050877 62 0.047
negative regulation of rna biosynthetic process GO:1902679 45 0.047
Mouse
inner ear morphogenesis GO:0042472 63 0.047
neuron projection extension GO:1990138 45 0.047
mesoderm morphogenesis GO:0048332 51 0.047
synaptic growth at neuromuscular junction GO:0051124 2 0.046
forebrain neuron differentiation GO:0021879 14 0.046
determination of heart left right asymmetry GO:0061371 117 0.045
regulation of cellular biosynthetic process GO:0031326 245 0.045
Zebrafish Mouse
positive regulation of stem cell proliferation GO:2000648 1 0.045
guanosine containing compound metabolic process GO:1901068 4 0.044
protein modification process GO:0036211 100 0.044
renal system development GO:0072001 94 0.044
Zebrafish
regeneration GO:0031099 91 0.044
modification dependent macromolecule catabolic process GO:0043632 3 0.044
heart jogging GO:0003146 40 0.044
axon regeneration GO:0031103 14 0.043
cranial nerve morphogenesis GO:0021602 15 0.043
meiotic nuclear division GO:0007126 4 0.043
negative regulation of retinal cell programmed cell death GO:0046671 2 0.043
somitogenesis GO:0001756 87 0.043
cardioblast migration GO:0003260 7 0.043
regulation of skeletal muscle tissue development GO:0048641 4 0.042
taxis GO:0042330 109 0.042
sexual reproduction GO:0019953 36 0.042
floor plate formation GO:0021508 12 0.042
developmental pigmentation GO:0048066 48 0.042
inner ear development GO:0048839 126 0.041
Zebrafish
formation of anatomical boundary GO:0048859 14 0.041
determination of digestive tract left right asymmetry GO:0071907 10 0.041
gtp catabolic process GO:0006184 2 0.040
chemical homeostasis GO:0048878 49 0.040
regulation of purine nucleotide catabolic process GO:0033121 2 0.040
auditory receptor cell fate determination GO:0042668 2 0.040
stem cell proliferation GO:0072089 4 0.040
Mouse
lateral line ganglion development GO:0048890 2 0.040
single organism transport GO:0044765 206 0.039
Mouse
hindbrain morphogenesis GO:0021575 22 0.038
peripheral nervous system neuron differentiation GO:0048934 28 0.038
Zebrafish
positive regulation of cell fate specification GO:0042660 1 0.038
septum transversum development GO:0003343 4 0.038
sympathetic nervous system development GO:0048485 3 0.038
thermosensory behavior GO:0040040 1 0.038
morphogenesis of embryonic epithelium GO:0016331 30 0.037
lateral line nerve glial cell development GO:0048937 6 0.037
regulation of inner ear receptor cell differentiation GO:2000980 1 0.037
Zebrafish
regulation of oligodendrocyte differentiation GO:0048713 1 0.037
forebrain generation of neurons GO:0021872 14 0.037
positive regulation of cell division GO:0051781 2 0.037
mammillary body development GO:0021767 4 0.036
cell cycle GO:0007049 93 0.036
Mouse
cell recognition GO:0008037 19 0.036
regulation of membrane potential GO:0042391 23 0.036
cellular ketone metabolic process GO:0042180 11 0.035
embryonic skeletal system development GO:0048706 97 0.035
immune system development GO:0002520 191 0.035
cell division GO:0051301 20 0.035
muscle cell development GO:0055001 115 0.035
Zebrafish
proteasomal protein catabolic process GO:0010498 2 0.035
regulation of transcription involved in cell fate commitment GO:0060850 1 0.035
closure of optic fissure GO:0061386 6 0.034
negative regulation of response to stimulus GO:0048585 104 0.034
Mouse
organic substance catabolic process GO:1901575 28 0.034
regulation of cell proliferation GO:0042127 37 0.033
Zebrafish Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.033
embryonic cranial skeleton morphogenesis GO:0048701 90 0.033
epithelial cell fate commitment GO:0072148 11 0.033
neuromast hair cell differentiation GO:0048886 12 0.032
lateral mesoderm development GO:0048368 23 0.032
posterior lateral line development GO:0048916 38 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
macromolecule modification GO:0043412 111 0.032
positive regulation of response to stimulus GO:0048584 80 0.032
water homeostasis GO:0030104 4 0.031
keratinocyte differentiation GO:0030216 0 0.031
exocrine system development GO:0035272 28 0.031
regulation of nucleotide catabolic process GO:0030811 2 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.031
embryonic heart tube left right pattern formation GO:0060971 5 0.031
skin development GO:0043588 54 0.031
stem cell development GO:0048864 82 0.030
single organism behavior GO:0044708 24 0.030
ectodermal placode development GO:0071696 37 0.030
endoderm development GO:0007492 49 0.030
cytoskeleton organization GO:0007010 96 0.030
endocrine process GO:0050886 2 0.030
cardiac chamber formation GO:0003207 4 0.030
gtp metabolic process GO:0046039 4 0.030
neural tube patterning GO:0021532 33 0.030
regulation of axon extension GO:0030516 24 0.030
cell cell signaling GO:0007267 52 0.030
Mouse
midbrain development GO:0030901 28 0.029
cellular protein metabolic process GO:0044267 129 0.029
cellular protein catabolic process GO:0044257 4 0.029
somite specification GO:0001757 12 0.029
spinal cord motor neuron differentiation GO:0021522 26 0.028
synapse organization GO:0050808 21 0.028
odontogenesis of dentin containing tooth GO:0042475 1 0.028
positive regulation of developmental process GO:0051094 50 0.028

six3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.154
sensory system disease DOID:0050155 0 0.126
nervous system disease DOID:863 0 0.126
eye and adnexa disease DOID:1492 0 0.082
eye disease DOID:5614 0 0.082