Danio rerio

10 known processes

slc1a2b

solute carrier family 1 (glial high affinity glutamate transporter), member 2b

(Aliases: eaat2,wu:fj34b12,zgc:65897,slc1a2,fj34b12)

slc1a2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.919
neuron differentiation GO:0030182 353 0.900
ion transmembrane transport GO:0034220 91 0.693
Mouse
cell morphogenesis GO:0000902 289 0.677
single organism localization GO:1902578 225 0.670
Mouse
regulation of multicellular organismal development GO:2000026 223 0.667
neuron neuron synaptic transmission GO:0007270 1 0.657
exocytosis GO:0006887 1 0.648
neurological system process GO:0050877 62 0.642
neuron development GO:0048666 262 0.636
regulation of membrane potential GO:0042391 23 0.603
cation transport GO:0006812 81 0.581
Mouse
synaptic transmission GO:0007268 35 0.567
eye development GO:0001654 277 0.563
cell projection organization GO:0030030 284 0.562
locomotion GO:0040011 313 0.541
locomotory behavior GO:0007626 34 0.501
neuron projection development GO:0031175 180 0.481
anion transmembrane transport GO:0098656 12 0.464
Mouse
ion transport GO:0006811 114 0.458
Mouse
regulation of localization GO:0032879 104 0.417
Mouse
inorganic cation transmembrane transport GO:0098662 50 0.393
Mouse
system process GO:0003008 185 0.377
regulation of neurogenesis GO:0050767 87 0.363
behavior GO:0007610 74 0.352
synaptic growth at neuromuscular junction GO:0051124 2 0.349
retina development in camera type eye GO:0060041 146 0.336
inorganic ion transmembrane transport GO:0098660 57 0.332
Mouse
axonogenesis GO:0007409 152 0.320
neuromuscular synaptic transmission GO:0007274 2 0.301
cation transmembrane transport GO:0098655 65 0.284
Mouse
regulation of developmental process GO:0050793 247 0.283
regulation of signaling GO:0023051 235 0.280
action potential GO:0001508 19 0.275
neuron projection morphogenesis GO:0048812 161 0.266
positive regulation of neuron apoptotic process GO:0043525 1 0.261
cell cell signaling GO:0007267 52 0.252
adult behavior GO:0030534 2 0.247
Mouse
cognition GO:0050890 1 0.244
macromolecular complex subunit organization GO:0043933 74 0.242
cellular component morphogenesis GO:0032989 336 0.241
regulation of nervous system development GO:0051960 90 0.241
cell morphogenesis involved in differentiation GO:0000904 195 0.238
small molecule metabolic process GO:0044281 77 0.227
regulation of synaptic plasticity GO:0048167 1 0.225
protein metabolic process GO:0019538 183 0.222
neuron projection regeneration GO:0031102 16 0.206
actin cytoskeleton organization GO:0030036 63 0.196
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.195
axon development GO:0061564 166 0.193
anterior posterior pattern specification GO:0009952 152 0.192
response to amino acid GO:0043200 2 0.191
Mouse
signal transduction GO:0007165 455 0.187
negative regulation of response to stimulus GO:0048585 104 0.182
regulation of multicellular organismal process GO:0051239 277 0.178
developmental growth GO:0048589 166 0.174
transmission of nerve impulse GO:0019226 19 0.172
cell projection morphogenesis GO:0048858 244 0.167
single organism transport GO:0044765 206 0.164
Mouse
monoamine transport GO:0015844 1 0.160
regulation of ion transmembrane transport GO:0034765 18 0.156
response to stress GO:0006950 263 0.153
Mouse
regulation of dendrite development GO:0050773 3 0.153
taxis GO:0042330 109 0.150
cell part morphogenesis GO:0032990 246 0.149
axon extension GO:0048675 45 0.148
cellular component biogenesis GO:0044085 178 0.147
positive regulation of programmed cell death GO:0043068 29 0.139
morphogenesis of an epithelium GO:0002009 333 0.135
transmembrane transport GO:0055085 120 0.133
Mouse
regulation of neuron differentiation GO:0045664 56 0.129
neurotransmitter transport GO:0006836 2 0.124
camera type eye development GO:0043010 222 0.121
regulation of biological quality GO:0065008 263 0.121
regulation of cell development GO:0060284 100 0.119
response to axon injury GO:0048678 14 0.112
synaptic transmission cholinergic GO:0007271 4 0.112
cellular component assembly GO:0022607 170 0.111
regulation of cell differentiation GO:0045595 142 0.109
cellular carbohydrate metabolic process GO:0044262 4 0.107
ion homeostasis GO:0050801 41 0.105
maintenance of location GO:0051235 4 0.105
pigmentation GO:0043473 85 0.103
response to external stimulus GO:0009605 264 0.101
Mouse
chemosensory behavior GO:0007635 1 0.096
multi organism process GO:0051704 134 0.094
response to wounding GO:0009611 116 0.092
Mouse
regulation of neurotransmitter transport GO:0051588 1 0.090
regulation of cell communication GO:0010646 232 0.089
regulation of cell projection organization GO:0031344 44 0.088
single organism membrane fusion GO:0044801 2 0.088
response to alkaloid GO:0043279 2 0.085
positive regulation of transport GO:0051050 2 0.084
Mouse
regulation of synapse assembly GO:0051963 3 0.082
cell growth GO:0016049 57 0.077
cell surface receptor signaling pathway GO:0007166 325 0.073
multi organism reproductive process GO:0044703 36 0.073
regulation of axonogenesis GO:0050770 32 0.072
neuronal action potential GO:0019228 18 0.070
transport GO:0006810 220 0.069
Mouse
amino acid transport GO:0006865 2 0.068
Mouse
neural retina development GO:0003407 49 0.067
regulation of ion transmembrane transporter activity GO:0032412 2 0.067
cellular protein complex assembly GO:0043623 19 0.066
macromolecular complex assembly GO:0065003 35 0.065
female gamete generation GO:0007292 14 0.063
wnt signaling pathway GO:0016055 80 0.062
cellular amino acid metabolic process GO:0006520 7 0.061
larval locomotory behavior GO:0008345 5 0.060
positive regulation of neuron death GO:1901216 1 0.060
convergent extension GO:0060026 118 0.059
regulation of cell morphogenesis GO:0022604 42 0.059
nucleocytoplasmic transport GO:0006913 4 0.059
taurine metabolic process GO:0019530 1 0.058
response to drug GO:0042493 3 0.058
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.058
membrane repolarization GO:0086009 2 0.057
small molecule catabolic process GO:0044282 3 0.056
sulfur compound metabolic process GO:0006790 13 0.056
localization of cell GO:0051674 244 0.055
cellular component movement GO:0006928 335 0.054
stem cell differentiation GO:0048863 117 0.054
organic acid catabolic process GO:0016054 3 0.054
regulation of response to stimulus GO:0048583 269 0.052
response to unfolded protein GO:0006986 2 0.051
negative regulation of biological process GO:0048519 304 0.050
regulation of transmembrane transport GO:0034762 18 0.050
cellular localization GO:0051641 97 0.049
muscle cell development GO:0055001 115 0.049
heterocycle metabolic process GO:0046483 290 0.049
establishment of synaptic vesicle localization GO:0097480 1 0.048
cellular macromolecular complex assembly GO:0034622 24 0.047
regulation of signal transduction GO:0009966 225 0.047
regulation of protein catabolic process GO:0042176 1 0.047
oxoacid metabolic process GO:0043436 31 0.046
lipid storage GO:0019915 1 0.046
biological adhesion GO:0022610 40 0.046
neuron projection extension GO:1990138 45 0.045
regulation of axon extension GO:0030516 24 0.045
atp catabolic process GO:0006200 4 0.045
regulation of synapse organization GO:0050807 3 0.044
positive regulation of signaling GO:0023056 56 0.044
ear development GO:0043583 127 0.044
calcium ion homeostasis GO:0055074 19 0.043
sensory organ morphogenesis GO:0090596 200 0.043
regulation of cellular component size GO:0032535 30 0.043
regulation of neuron projection development GO:0010975 40 0.043
establishment of blood brain barrier GO:0060856 2 0.043
regulation of cell growth GO:0001558 29 0.042
regulation of transport GO:0051049 45 0.042
Mouse
muscle cell differentiation GO:0042692 139 0.042
carboxylic acid catabolic process GO:0046395 3 0.041
synaptic vesicle transport GO:0048489 1 0.041
single organism behavior GO:0044708 24 0.041
regulation of ion transport GO:0043269 22 0.040
response to radiation GO:0009314 51 0.040
Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.040
actin filament based process GO:0030029 64 0.040
multicellular organismal signaling GO:0035637 22 0.039
regulation of protein complex assembly GO:0043254 3 0.039
regulation of protein transport GO:0051223 3 0.039
regulation of cellular component organization GO:0051128 86 0.038
guanosine containing compound metabolic process GO:1901068 4 0.038
multicellular organismal water homeostasis GO:0050891 1 0.038
regulation of establishment of protein localization GO:0070201 4 0.037
visual perception GO:0007601 17 0.037
negative regulation of cell communication GO:0010648 96 0.037
tube morphogenesis GO:0035239 349 0.037
microtubule based process GO:0007017 60 0.036
regulation of intracellular protein transport GO:0033157 3 0.036
epithelial cell differentiation GO:0030855 116 0.036
sensory organ development GO:0007423 393 0.036
negative regulation of multicellular organismal process GO:0051241 69 0.035
l amino acid transport GO:0015807 1 0.035
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.035
establishment of localization GO:0051234 244 0.033
Mouse
larval development GO:0002164 2 0.033
nucleobase containing compound metabolic process GO:0006139 274 0.033
axon ensheathment GO:0008366 18 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.032
cytoskeleton organization GO:0007010 96 0.032
macromolecule localization GO:0033036 54 0.032
cellular response to stress GO:0033554 62 0.032
carbohydrate metabolic process GO:0005975 12 0.032
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.032
ensheathment of neurons GO:0007272 18 0.032
hormone transport GO:0009914 2 0.031
programmed cell death GO:0012501 119 0.031
regulation of cellular ketone metabolic process GO:0010565 7 0.031
organic acid metabolic process GO:0006082 31 0.030
regulation of anatomical structure morphogenesis GO:0022603 130 0.029
brain development GO:0007420 293 0.029
Mouse
developmental maturation GO:0021700 34 0.029
regulation of dendrite morphogenesis GO:0048814 3 0.029
chemical homeostasis GO:0048878 49 0.029
regulation of metal ion transport GO:0010959 4 0.028
gastrulation with mouth forming second GO:0001702 44 0.028
cellular cation homeostasis GO:0030003 17 0.028
cellular amine metabolic process GO:0044106 2 0.028
ammonia homeostasis GO:0097272 3 0.027
single organism metabolic process GO:0044710 217 0.027
cell adhesion GO:0007155 40 0.027
nuclear transport GO:0051169 4 0.027
growth GO:0040007 174 0.026
Mouse
regulation of sodium ion transport GO:0002028 2 0.026
regulation of binding GO:0051098 3 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
nucleobase containing small molecule metabolic process GO:0055086 32 0.026
blood vessel development GO:0001568 246 0.025
regulation of filopodium assembly GO:0051489 2 0.025
organelle organization GO:0006996 227 0.025
protein complex biogenesis GO:0070271 30 0.025
determination of heart left right asymmetry GO:0061371 117 0.025
regionalization GO:0003002 274 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
regulation of primary metabolic process GO:0080090 311 0.025
aging GO:0007568 2 0.025
Mouse
locomotor rhythm GO:0045475 3 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
response to chemical GO:0042221 320 0.024
Mouse
cellular ketone metabolic process GO:0042180 11 0.024
carboxylic acid biosynthetic process GO:0046394 12 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
cell cycle g1 s phase transition GO:0044843 1 0.023
reproductive process GO:0022414 40 0.023
enzyme linked receptor protein signaling pathway GO:0007167 106 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
divalent metal ion transport GO:0070838 20 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
negative regulation of signaling GO:0023057 96 0.023
calcium mediated signaling GO:0019722 2 0.023
cellular biosynthetic process GO:0044249 286 0.022
regulation of neurotransmitter levels GO:0001505 5 0.022
axon ensheathment in central nervous system GO:0032291 2 0.022
axon regeneration GO:0031103 14 0.022
amine metabolic process GO:0009308 2 0.022
otolith development GO:0048840 32 0.022
organic anion transport GO:0015711 15 0.022
Mouse
regulation of cell size GO:0008361 29 0.022
positive regulation of catabolic process GO:0009896 4 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
phagocytosis GO:0006909 3 0.021
purine nucleotide metabolic process GO:0006163 27 0.021
multicellular organismal reproductive process GO:0048609 35 0.021
single organism organelle organization GO:1902589 199 0.021
water homeostasis GO:0030104 4 0.021
central nervous system development GO:0007417 387 0.021
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.021
response to organic substance GO:0010033 153 0.021
Mouse
digestive system development GO:0055123 289 0.021
dendrite development GO:0016358 9 0.021
larval behavior GO:0030537 5 0.020
sodium ion transmembrane transport GO:0035725 21 0.020
Mouse
regulation of protein targeting GO:1903533 2 0.020
cellular homeostasis GO:0019725 26 0.020
synaptic vesicle endocytosis GO:0048488 1 0.020
epiboly GO:0090504 41 0.020
organelle fusion GO:0048284 3 0.020
organelle assembly GO:0070925 110 0.020
gamete generation GO:0007276 33 0.020
positive regulation of cellular process GO:0048522 201 0.019
vasculature development GO:0001944 278 0.019
chemotaxis GO:0006935 104 0.019
post embryonic morphogenesis GO:0009886 4 0.019
regulation of growth rate GO:0040009 1 0.019
monovalent inorganic cation transport GO:0015672 42 0.019
Mouse
organonitrogen compound biosynthetic process GO:1901566 47 0.019
neuroblast proliferation GO:0007405 2 0.019
regulation of cellular protein metabolic process GO:0032268 52 0.019
homeostatic process GO:0042592 142 0.019
central nervous system neuron differentiation GO:0021953 74 0.019
organic substance transport GO:0071702 58 0.019
Mouse
regulation of cell projection assembly GO:0060491 4 0.019
regulation of cellular protein catabolic process GO:1903362 1 0.019
morphogenesis of an epithelial sheet GO:0002011 49 0.019
negative regulation of metabolic process GO:0009892 86 0.018
negative regulation of wnt signaling pathway GO:0030178 30 0.018
chordate embryonic development GO:0043009 271 0.018
organelle localization GO:0051640 49 0.018
positive regulation of response to stimulus GO:0048584 80 0.018
negative regulation of peptidase activity GO:0010466 10 0.018
cellular macromolecule localization GO:0070727 21 0.018
negative regulation of signal transduction GO:0009968 94 0.018
regulation of locomotion GO:0040012 55 0.018
gtp metabolic process GO:0046039 4 0.018
cell matrix adhesion GO:0007160 4 0.017
regulation of system process GO:0044057 40 0.017
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.017
homologous chromosome segregation GO:0045143 1 0.017
blood vessel morphogenesis GO:0048514 216 0.017
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
protein localization GO:0008104 40 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
gene expression GO:0010467 252 0.017
calcium ion import GO:0070509 4 0.017
protein complex subunit organization GO:0071822 46 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
ribonucleotide metabolic process GO:0009259 27 0.017
regulation of tube size GO:0035150 2 0.017
inner ear development GO:0048839 126 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.016
mesenchymal cell development GO:0014031 78 0.016
cation homeostasis GO:0055080 33 0.016
response to carbohydrate GO:0009743 3 0.016
death GO:0016265 121 0.016
neuromuscular junction development GO:0007528 9 0.016
peptide transport GO:0015833 1 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.016
regulation of transporter activity GO:0032409 2 0.016
glial cell differentiation GO:0010001 42 0.016
single organism biosynthetic process GO:0044711 71 0.016
regulation of synaptic transmission GO:0050804 4 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
regulation of stem cell differentiation GO:2000736 4 0.016
circulatory system process GO:0003013 87 0.016
g protein coupled receptor signaling pathway GO:0007186 74 0.016
muscle system process GO:0003012 20 0.016
regulation of hormone secretion GO:0046883 2 0.016
regulation of programmed cell death GO:0043067 101 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
positive regulation of cell communication GO:0010647 56 0.016
embryonic heart tube morphogenesis GO:0003143 108 0.016
cellular chemical homeostasis GO:0055082 17 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
regulation of bone mineralization GO:0030500 2 0.015
cell cycle process GO:0022402 53 0.015
divalent inorganic cation homeostasis GO:0072507 22 0.015
organic hydroxy compound transport GO:0015850 14 0.015
embryonic skeletal joint development GO:0072498 3 0.015
metal ion homeostasis GO:0055065 26 0.015
cellular protein modification process GO:0006464 100 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
startle response GO:0001964 4 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
glucose homeostasis GO:0042593 1 0.015
cellular response to organic substance GO:0071310 105 0.015
negative regulation of biosynthetic process GO:0009890 55 0.014
cell proliferation in hindbrain GO:0021534 4 0.014
reflex GO:0060004 2 0.014
cell migration GO:0016477 237 0.014
regulation of developmental growth GO:0048638 38 0.014
negative regulation of molecular function GO:0044092 23 0.014
skin development GO:0043588 54 0.014
cell substrate adherens junction assembly GO:0007045 1 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
response to other organism GO:0051707 97 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
stem cell proliferation GO:0072089 4 0.014
synaptic vesicle localization GO:0097479 1 0.014
head development GO:0060322 303 0.014
Mouse
gtp catabolic process GO:0006184 2 0.014
sensory perception of light stimulus GO:0050953 19 0.014
neurotransmitter metabolic process GO:0042133 3 0.014
regulation of canonical wnt signaling pathway GO:0060828 34 0.013
swimming behavior GO:0036269 8 0.013
synaptic transmission glycinergic GO:0060012 1 0.013
response to glucose GO:0009749 3 0.013
positive regulation of multicellular organismal process GO:0051240 52 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
multicellular organism reproduction GO:0032504 35 0.013
positive regulation of secretion GO:0051047 1 0.013
neural crest cell differentiation GO:0014033 72 0.013
regulation of proteolysis GO:0030162 24 0.013
regulation of homeostatic process GO:0032844 9 0.013
muscle organ development GO:0007517 101 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
epithelial cell morphogenesis GO:0003382 2 0.013
rna localization GO:0006403 4 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
response to endogenous stimulus GO:0009719 83 0.013
Mouse
response to abiotic stimulus GO:0009628 122 0.013
Mouse
regulation of cell substrate adhesion GO:0010810 1 0.013
regulation of cell maturation GO:1903429 1 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
neurotransmitter secretion GO:0007269 2 0.013
nitrogen compound transport GO:0071705 23 0.013
Mouse
energy reserve metabolic process GO:0006112 2 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
regulation of hydrolase activity GO:0051336 28 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
glial cell development GO:0021782 20 0.012
developmental pigmentation GO:0048066 48 0.012
actomyosin structure organization GO:0031032 53 0.012
cell fate commitment GO:0045165 99 0.012
thermosensory behavior GO:0040040 1 0.012
positive regulation of biological process GO:0048518 253 0.012
Mouse
apoptotic process GO:0006915 116 0.012
myotube differentiation GO:0014902 45 0.012
cell death GO:0008219 121 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
cell division GO:0051301 20 0.012
regulation of protein maturation GO:1903317 10 0.012
regulation of protein metabolic process GO:0051246 56 0.012
synaptic vesicle recycling GO:0036465 1 0.012
specification of symmetry GO:0009799 204 0.012
embryonic organ development GO:0048568 381 0.012
regulation of anatomical structure size GO:0090066 33 0.011
monocarboxylic acid catabolic process GO:0072329 3 0.011
regulation of growth GO:0040008 42 0.011
regulation of extent of cell growth GO:0061387 29 0.011
monocarboxylic acid biosynthetic process GO:0072330 12 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
cell motility GO:0048870 244 0.011
regulation of glutamate receptor signaling pathway GO:1900449 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regulation of cytoskeleton organization GO:0051493 11 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
single organism reproductive process GO:0044702 40 0.011
hormone secretion GO:0046879 2 0.011
mechanosensory behavior GO:0007638 2 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
gliogenesis GO:0042063 45 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
nucleotide metabolic process GO:0009117 28 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
muscle structure development GO:0061061 196 0.010
cellular protein metabolic process GO:0044267 129 0.010
membrane fusion GO:0061025 2 0.010
protein import into nucleus GO:0006606 3 0.010
intracellular mrna localization GO:0008298 1 0.010
negative regulation of rna metabolic process GO:0051253 48 0.010
muscle contraction GO:0006936 18 0.010
heart morphogenesis GO:0003007 156 0.010
carbohydrate homeostasis GO:0033500 1 0.010
cytokinesis GO:0000910 3 0.010
muscle tissue development GO:0060537 110 0.010
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 1 0.010
regulation of feeding behavior GO:0060259 5 0.010
establishment of organelle localization GO:0051656 45 0.010
positive regulation of cell death GO:0010942 29 0.010

slc1a2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.018
urinary system disease DOID:18 0 0.014