Danio rerio

30 known processes

slc26a5

solute carrier family 26, member 5

(Aliases: fb74g12,fb73d12,wu:fb74g12,pres,wu:fb73d12)

slc26a5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anion transport GO:0006820 38 0.457
signal transduction GO:0007165 455 0.171
regulation of cell communication GO:0010646 232 0.152
negative regulation of biological process GO:0048519 304 0.149
nucleic acid metabolic process GO:0090304 244 0.128
cellular macromolecule biosynthetic process GO:0034645 224 0.126
organic cyclic compound biosynthetic process GO:1901362 223 0.107
nucleic acid templated transcription GO:0097659 181 0.106
cellular macromolecule metabolic process GO:0044260 391 0.096
neuron neuron synaptic transmission GO:0007270 1 0.089
lipid storage GO:0019915 1 0.088
proteasomal protein catabolic process GO:0010498 2 0.088
microtubule organizing center organization GO:0031023 1 0.087
negative regulation of cellular process GO:0048523 283 0.086
regulation of multicellular organismal process GO:0051239 277 0.086
establishment of localization GO:0051234 244 0.084
regulation of nucleic acid templated transcription GO:1903506 213 0.083
regulation of cellular metabolic process GO:0031323 320 0.081
maintenance of location GO:0051235 4 0.080
larval development GO:0002164 2 0.080
regulation of biosynthetic process GO:0009889 250 0.080
nucleobase containing compound metabolic process GO:0006139 274 0.074
sensory organ morphogenesis GO:0090596 200 0.074
cell surface receptor signaling pathway GO:0007166 325 0.074
regulation of rna metabolic process GO:0051252 224 0.073
cell projection organization GO:0030030 284 0.072
neuron projection development GO:0031175 180 0.070
regulation of signal transduction GO:0009966 225 0.069
macromolecule biosynthetic process GO:0009059 227 0.069
death GO:0016265 121 0.068
organic substance biosynthetic process GO:1901576 289 0.067
regulation of response to stimulus GO:0048583 269 0.067
synaptic vesicle transport GO:0048489 1 0.066
biosynthetic process GO:0009058 294 0.065
single organism metabolic process GO:0044710 217 0.063
positive regulation of catabolic process GO:0009896 4 0.062
rna metabolic process GO:0016070 219 0.062
autophagy GO:0006914 4 0.061
organic cyclic compound metabolic process GO:1901360 301 0.060
ubiquitin dependent protein catabolic process GO:0006511 3 0.060
meiotic nuclear division GO:0007126 4 0.058
regulation of rna biosynthetic process GO:2001141 213 0.058
nucleobase containing compound biosynthetic process GO:0034654 205 0.057
regulation of transcription dna templated GO:0006355 213 0.056
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.055
rna biosynthetic process GO:0032774 181 0.055
regulation of primary metabolic process GO:0080090 311 0.055
regulation of multicellular organism growth GO:0040014 4 0.055
protein metabolic process GO:0019538 183 0.055
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.054
establishment of protein localization to organelle GO:0072594 4 0.054
organelle fusion GO:0048284 3 0.053
neuron projection morphogenesis GO:0048812 161 0.052
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.052
growth GO:0040007 174 0.051
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.051
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.050
neuron differentiation GO:0030182 353 0.050
cell projection morphogenesis GO:0048858 244 0.049
negative regulation of cell communication GO:0010648 96 0.049
eye development GO:0001654 277 0.049
cellular response to nutrient levels GO:0031669 2 0.048
cellular response to external stimulus GO:0071496 2 0.048
single organism localization GO:1902578 225 0.047
generation of neurons GO:0048699 385 0.046
multicellular organism growth GO:0035264 4 0.044
cellular protein metabolic process GO:0044267 129 0.044
membrane fusion GO:0061025 2 0.044
nitrogen compound metabolic process GO:0006807 319 0.043
cellular response to starvation GO:0009267 1 0.043
dicarboxylic acid transport GO:0006835 1 0.043
negative regulation of response to stimulus GO:0048585 104 0.043
cognition GO:0050890 1 0.043
modification dependent protein catabolic process GO:0019941 3 0.043
golgi vesicle transport GO:0048193 3 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.042
neuron development GO:0048666 262 0.042
positive regulation of transport GO:0051050 2 0.042
regulation of signaling GO:0023051 235 0.042
neurotransmitter transport GO:0006836 2 0.041
cell part morphogenesis GO:0032990 246 0.041
cell growth GO:0016049 57 0.041
transcription dna templated GO:0006351 181 0.041
cellular carbohydrate metabolic process GO:0044262 4 0.040
apoptotic process GO:0006915 116 0.039
aromatic compound biosynthetic process GO:0019438 217 0.039
homeostatic process GO:0042592 142 0.039
Zebrafish
steroid hormone secretion GO:0035929 1 0.038
modification dependent macromolecule catabolic process GO:0043632 3 0.038
programmed cell death GO:0012501 119 0.037
energy reserve metabolic process GO:0006112 2 0.037
single organism membrane fusion GO:0044801 2 0.037
axon development GO:0061564 166 0.037
adult behavior GO:0030534 2 0.037
amino acid transport GO:0006865 2 0.037
brain development GO:0007420 293 0.036
cellular nitrogen compound metabolic process GO:0034641 290 0.036
nucleocytoplasmic transport GO:0006913 4 0.036
synaptic vesicle recycling GO:0036465 1 0.036
gene expression GO:0010467 252 0.035
neuromuscular process controlling balance GO:0050885 3 0.035
regulation of synapse assembly GO:0051963 3 0.035
cellular protein catabolic process GO:0044257 4 0.035
cell morphogenesis involved in differentiation GO:0000904 195 0.035
cellular nitrogen compound biosynthetic process GO:0044271 218 0.035
single organism nuclear import GO:1902593 3 0.035
negative regulation of signaling GO:0023057 96 0.035
heterocycle biosynthetic process GO:0018130 215 0.035
cellular response to biotic stimulus GO:0071216 3 0.035
carbohydrate biosynthetic process GO:0016051 1 0.035
hematopoietic or lymphoid organ development GO:0048534 191 0.034
regulation of macromolecule biosynthetic process GO:0010556 225 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.033
head development GO:0060322 303 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.033
macroautophagy GO:0016236 1 0.033
cell morphogenesis GO:0000902 289 0.033
hemopoiesis GO:0030097 183 0.032
nuclear transport GO:0051169 4 0.032
regulation of autophagy GO:0010506 3 0.032
cellular component disassembly GO:0022411 1 0.032
protein polyubiquitination GO:0000209 4 0.032
regulation of synapse organization GO:0050807 3 0.032
central nervous system development GO:0007417 387 0.031
regulation of protein catabolic process GO:0042176 1 0.031
response to glucose GO:0009749 3 0.031
meiotic cell cycle process GO:1903046 3 0.031
aging GO:0007568 2 0.031
protein modification process GO:0036211 100 0.031
synaptic vesicle localization GO:0097479 1 0.030
heterocycle metabolic process GO:0046483 290 0.030
cellular response to extracellular stimulus GO:0031668 2 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.029
macromolecular complex disassembly GO:0032984 1 0.029
guanosine containing compound catabolic process GO:1901069 2 0.029
organic anion transport GO:0015711 15 0.028
axonogenesis GO:0007409 152 0.028
developmental growth GO:0048589 166 0.028
nuclear import GO:0051170 3 0.028
protein localization to nucleus GO:0034504 3 0.028
gtp catabolic process GO:0006184 2 0.028
regulation of protein complex assembly GO:0043254 3 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
negative regulation of macromolecule metabolic process GO:0010605 76 0.027
gtp metabolic process GO:0046039 4 0.027
reflex GO:0060004 2 0.027
response to external stimulus GO:0009605 264 0.027
single organism transport GO:0044765 206 0.027
regulation of neurogenesis GO:0050767 87 0.027
response to stress GO:0006950 263 0.026
Zebrafish
regionalization GO:0003002 274 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.026
protein import into nucleus GO:0006606 3 0.026
endosome organization GO:0007032 2 0.026
negative regulation of signal transduction GO:0009968 94 0.026
regulation of protein polymerization GO:0032271 2 0.025
regulation of biological quality GO:0065008 263 0.025
establishment of synaptic vesicle localization GO:0097480 1 0.025
camera type eye development GO:0043010 222 0.025
cellular response to molecule of bacterial origin GO:0071219 3 0.025
response to hexose GO:0009746 3 0.025
protein complex disassembly GO:0043241 1 0.025
insulin like growth factor receptor signaling pathway GO:0048009 4 0.025
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.025
cell death GO:0008219 121 0.024
system process GO:0003008 185 0.024
regulation of organelle assembly GO:1902115 4 0.024
cellular biosynthetic process GO:0044249 286 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
regulation of response to nutrient levels GO:0032107 1 0.024
small molecule metabolic process GO:0044281 77 0.023
protein polymerization GO:0051258 4 0.023
localization of cell GO:0051674 244 0.023
visual perception GO:0007601 17 0.022
small gtpase mediated signal transduction GO:0007264 8 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.022
regulation of apoptotic process GO:0042981 98 0.022
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.022
regulation of developmental process GO:0050793 247 0.022
immune system process GO:0002376 241 0.022
meiotic chromosome segregation GO:0045132 3 0.022
single organism biosynthetic process GO:0044711 71 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.021
response to chemical GO:0042221 320 0.021
stem cell proliferation GO:0072089 4 0.021
negative regulation of ras protein signal transduction GO:0046580 1 0.021
regulation of intracellular ph GO:0051453 1 0.021
regulation of cytokine production GO:0001817 3 0.021
hormone transport GO:0009914 2 0.021
monovalent inorganic cation transport GO:0015672 42 0.020
Zebrafish
inositol phosphate metabolic process GO:0043647 1 0.020
neurotransmitter secretion GO:0007269 2 0.020
regulation of reproductive process GO:2000241 4 0.020
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.020
fat soluble vitamin metabolic process GO:0006775 4 0.020
phagocytosis GO:0006909 3 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
regulation of sodium ion transport GO:0002028 2 0.020
lateral inhibition GO:0046331 1 0.020
negative regulation of cellular metabolic process GO:0031324 77 0.020
epithelial cell morphogenesis GO:0003382 2 0.020
regulation of cell development GO:0060284 100 0.020
regulation of nervous system development GO:0051960 90 0.020
regulation of growth GO:0040008 42 0.020
i kappab kinase nf kappab signaling GO:0007249 4 0.019
neuroblast proliferation GO:0007405 2 0.019
regulation of cell death GO:0010941 103 0.019
regulation of organ growth GO:0046620 3 0.019
organelle organization GO:0006996 227 0.019
regulation of programmed cell death GO:0043067 101 0.018
multi organism process GO:0051704 134 0.018
toll like receptor signaling pathway GO:0002224 4 0.018
response to abiotic stimulus GO:0009628 122 0.018
Zebrafish
regulation of cellular protein catabolic process GO:1903362 1 0.018
protein targeting to nucleus GO:0044744 3 0.018
regulation of dendrite development GO:0050773 3 0.018
response to monosaccharide GO:0034284 3 0.018
centrosome organization GO:0051297 1 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.018
regulation of metabolic process GO:0019222 359 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
regulation of cell projection organization GO:0031344 44 0.018
negative regulation of cytoplasmic transport GO:1903650 2 0.018
regulation of carbohydrate metabolic process GO:0006109 4 0.017
regulation of response to extracellular stimulus GO:0032104 1 0.017
protein import GO:0017038 3 0.017
synaptic vesicle endocytosis GO:0048488 1 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
anion transmembrane transport GO:0098656 12 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
negative regulation of protein complex assembly GO:0031333 1 0.017
homeostasis of number of cells GO:0048872 62 0.017
sensory organ development GO:0007423 393 0.017
cellular component morphogenesis GO:0032989 336 0.017
cell aging GO:0007569 2 0.017
developmental cell growth GO:0048588 52 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
skeletal system development GO:0001501 181 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
carbohydrate homeostasis GO:0033500 1 0.016
negative regulation of programmed cell death GO:0043069 58 0.016
digestive tract morphogenesis GO:0048546 231 0.016
protein homooligomerization GO:0051260 3 0.016
regulation of lipid transport GO:0032368 4 0.015
transmembrane transport GO:0055085 120 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
vestibular reflex GO:0060005 2 0.015
immune system development GO:0002520 191 0.015
erythrocyte homeostasis GO:0034101 55 0.015
regulation of protein transport GO:0051223 3 0.015
response to nutrient GO:0007584 3 0.015
actin filament based movement GO:0030048 1 0.015
negative regulation of synapse assembly GO:0051964 2 0.015
regulation of cellular ph GO:0030641 1 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of neuron differentiation GO:0045664 56 0.015
cell migration GO:0016477 237 0.015
negative regulation of metabolic process GO:0009892 86 0.015
hydrogen peroxide metabolic process GO:0042743 2 0.015
inner ear development GO:0048839 126 0.015
response to biotic stimulus GO:0009607 97 0.014
cellular response to hypoxia GO:0071456 1 0.014
organelle localization GO:0051640 49 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
striated muscle cell differentiation GO:0051146 129 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.014
organic acid transport GO:0015849 9 0.014
negative regulation of cellular biosynthetic process GO:0031327 55 0.014
hormone secretion GO:0046879 2 0.014
signal transduction in absence of ligand GO:0038034 1 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
myeloid cell homeostasis GO:0002262 56 0.014
ion transport GO:0006811 114 0.014
primitive hemopoiesis GO:0060215 27 0.014
embryonic limb morphogenesis GO:0030326 2 0.014
positive regulation of biological process GO:0048518 253 0.014
vesicle localization GO:0051648 27 0.014
response to vitamin GO:0033273 3 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
smooth muscle tissue development GO:0048745 1 0.013
actin filament polymerization GO:0030041 2 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
negative regulation of tor signaling GO:0032007 2 0.013
response to hydrogen peroxide GO:0042542 3 0.013
phosphorus metabolic process GO:0006793 109 0.013
glucose import GO:0046323 2 0.013
double strand break repair GO:0006302 3 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
regulation of carbohydrate biosynthetic process GO:0043255 1 0.013
regulation of response to oxidative stress GO:1902882 2 0.013
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.013
stem cell division GO:0017145 1 0.013
camera type eye morphogenesis GO:0048593 108 0.013
regulation of cell shape GO:0008360 1 0.013
neurological system process GO:0050877 62 0.013
protein dephosphorylation GO:0006470 3 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
forebrain cell migration GO:0021885 1 0.013
embryonic organ development GO:0048568 381 0.013
synaptic transmission GO:0007268 35 0.013
endocrine process GO:0050886 2 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
odontogenesis of dentin containing tooth GO:0042475 1 0.013
negative regulation of cytokine production GO:0001818 1 0.013
polyol metabolic process GO:0019751 1 0.013
response to organic substance GO:0010033 153 0.013
positive regulation of secretion GO:0051047 1 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
single organism organelle organization GO:1902589 199 0.012
regulation of cell growth GO:0001558 29 0.012
regulation of hormone secretion GO:0046883 2 0.012
alpha amino acid metabolic process GO:1901605 3 0.012
tissue remodeling GO:0048771 4 0.012
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.012
regulation of transporter activity GO:0032409 2 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
cellular response to organic substance GO:0071310 105 0.012
somatic muscle development GO:0007525 4 0.012
skin development GO:0043588 54 0.012
nucleobase containing compound transport GO:0015931 2 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
negative regulation of protein transport GO:0051224 3 0.012
cell motility GO:0048870 244 0.012
regulation of cellular component organization GO:0051128 86 0.012
cellular protein complex disassembly GO:0043624 1 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
regulation of cell projection assembly GO:0060491 4 0.012
negative regulation of multi organism process GO:0043901 3 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
exocytosis GO:0006887 1 0.012
equilibrioception GO:0050957 2 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
locomotory behavior GO:0007626 34 0.011
positive regulation of protein kinase b signaling GO:0051897 1 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
establishment of vesicle localization GO:0051650 24 0.011
vacuolar transport GO:0007034 2 0.011
protein targeting to membrane GO:0006612 1 0.011
homeostasis of number of cells within a tissue GO:0048873 4 0.011
centrosome cycle GO:0007098 1 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.011
inorganic anion transport GO:0015698 25 0.011
regulation of alcohol biosynthetic process GO:1902930 1 0.011
regulation of ph GO:0006885 3 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
eye morphogenesis GO:0048592 144 0.011
locomotion GO:0040011 313 0.011
mitochondrion organization GO:0007005 4 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
response to alkaloid GO:0043279 2 0.011
antimicrobial humoral response GO:0019730 2 0.011
response to oxygen containing compound GO:1901700 55 0.011
vasculature development GO:0001944 278 0.011
compound eye development GO:0048749 2 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
response to carbohydrate GO:0009743 3 0.011
ion transmembrane transport GO:0034220 91 0.011
telomere maintenance GO:0000723 1 0.011
regulation of circadian sleep wake cycle GO:0042749 1 0.011
peptidyl serine modification GO:0018209 2 0.011
cellular localization GO:0051641 97 0.011
carbohydrate metabolic process GO:0005975 12 0.011
stem cell maintenance GO:0019827 4 0.011
regulation of muscle contraction GO:0006937 3 0.011
cellular response to stress GO:0033554 62 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
catabolic process GO:0009056 32 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
erythrocyte differentiation GO:0030218 54 0.011
response to copper ion GO:0046688 13 0.011
nuclear export GO:0051168 1 0.011
phosphatidylinositol metabolic process GO:0046488 7 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
mitotic recombination GO:0006312 2 0.011
regulation of circadian rhythm GO:0042752 4 0.010
regulation of cell differentiation GO:0045595 142 0.010
regulation of molecular function GO:0065009 70 0.010
cell substrate adhesion GO:0031589 4 0.010
regulation of endocrine process GO:0044060 2 0.010
vasculogenesis GO:0001570 41 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
microtubule based process GO:0007017 60 0.010
intracellular signal transduction GO:0035556 85 0.010
regulation of metal ion transport GO:0010959 4 0.010
regulation of response to cytokine stimulus GO:0060759 3 0.010
regulation of tube size GO:0035150 2 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
cellular component movement GO:0006928 335 0.010
muscle structure development GO:0061061 196 0.010
peripheral nervous system development GO:0007422 55 0.010
lysosomal transport GO:0007041 2 0.010

slc26a5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
immune system disease DOID:2914 0 0.019
hematopoietic system disease DOID:74 0 0.019
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
sensory system disease DOID:0050155 0 0.012
nervous system disease DOID:863 0 0.012
auditory system disease DOID:2742 0 0.011
nonsyndromic deafness DOID:0050563 0 0.011
musculoskeletal system disease DOID:17 0 0.010