Danio rerio

75 known processes

slc40a1

solute carrier family 40 (iron-regulated transporter), member 1

(Aliases: slc39a1,weh,FPN1)

slc40a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.605
lipid storage GO:0019915 1 0.375
response to external stimulus GO:0009605 264 0.320
response to chemical GO:0042221 320 0.311
phagocytosis GO:0006909 3 0.239
embryo development ending in birth or egg hatching GO:0009792 271 0.222
locomotion GO:0040011 313 0.215
cellular aromatic compound metabolic process GO:0006725 295 0.178
Mouse
transcription dna templated GO:0006351 181 0.172
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.168
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.165
regulation of cell communication GO:0010646 232 0.164
cell projection organization GO:0030030 284 0.163
signal transduction GO:0007165 455 0.161
nitrogen compound metabolic process GO:0006807 319 0.157
Mouse
cell projection morphogenesis GO:0048858 244 0.151
regulation of transcription dna templated GO:0006355 213 0.144
Mouse
maintenance of location GO:0051235 4 0.143
taxis GO:0042330 109 0.137
tissue remodeling GO:0048771 4 0.132
cellular response to xenobiotic stimulus GO:0071466 35 0.125
response to xenobiotic stimulus GO:0009410 45 0.117
regulation of biological quality GO:0065008 263 0.115
regulation of signaling GO:0023051 235 0.112
organic cyclic compound biosynthetic process GO:1901362 223 0.098
Mouse
determination of left right symmetry GO:0007368 179 0.089
biosynthetic process GO:0009058 294 0.089
aromatic compound biosynthetic process GO:0019438 217 0.088
Mouse
positive regulation of transport GO:0051050 2 0.088
negative regulation of biological process GO:0048519 304 0.085
Mouse
nucleic acid templated transcription GO:0097659 181 0.083
Mouse
generation of neurons GO:0048699 385 0.083
positive regulation of biological process GO:0048518 253 0.082
Mouse
regulation of signal transduction GO:0009966 225 0.082
response to stress GO:0006950 263 0.081
organic substance biosynthetic process GO:1901576 289 0.079
regulation of metabolic process GO:0019222 359 0.075
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.075
aging GO:0007568 2 0.074
cell part morphogenesis GO:0032990 246 0.071
single organism localization GO:1902578 225 0.071
single organism metabolic process GO:0044710 217 0.070
cellular biosynthetic process GO:0044249 286 0.068
cell morphogenesis involved in differentiation GO:0000904 195 0.068
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.068
Mouse
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.065
nucleobase containing compound biosynthetic process GO:0034654 205 0.065
Mouse
cellular response to external stimulus GO:0071496 2 0.065
protein metabolic process GO:0019538 183 0.064
cellular nitrogen compound biosynthetic process GO:0044271 218 0.064
Mouse
determination of bilateral symmetry GO:0009855 204 0.064
macromolecule biosynthetic process GO:0009059 227 0.063
cellular macromolecule metabolic process GO:0044260 391 0.063
neuron development GO:0048666 262 0.062
blood vessel morphogenesis GO:0048514 216 0.060
regulation of autophagy GO:0010506 3 0.060
meiotic nuclear division GO:0007126 4 0.059
cellular protein catabolic process GO:0044257 4 0.059
chemotaxis GO:0006935 104 0.057
membrane invagination GO:0010324 1 0.057
cellular component movement GO:0006928 335 0.057
negative regulation of cellular process GO:0048523 283 0.056
Mouse
liver development GO:0001889 96 0.056
cellular response to starvation GO:0009267 1 0.055
neuron projection morphogenesis GO:0048812 161 0.054
modification dependent protein catabolic process GO:0019941 3 0.053
morphogenesis of an epithelium GO:0002009 333 0.053
organelle organization GO:0006996 227 0.050
regulation of response to stimulus GO:0048583 269 0.050
ion homeostasis GO:0050801 41 0.048
Human Mouse
nucleic acid metabolic process GO:0090304 244 0.047
Mouse
specification of symmetry GO:0009799 204 0.046
cell surface receptor signaling pathway GO:0007166 325 0.045
ubiquitin dependent protein catabolic process GO:0006511 3 0.045
gene expression GO:0010467 252 0.045
Mouse
phagocytosis engulfment GO:0006911 1 0.044
localization of cell GO:0051674 244 0.043
cell morphogenesis GO:0000902 289 0.042
axonogenesis GO:0007409 152 0.042
neuron differentiation GO:0030182 353 0.042
negative regulation of signal transduction GO:0009968 94 0.041
cellular macromolecule biosynthetic process GO:0034645 224 0.041
cellular component morphogenesis GO:0032989 336 0.040
regulation of ph GO:0006885 3 0.040
regulation of synapse assembly GO:0051963 3 0.040
regulation of nitrogen compound metabolic process GO:0051171 251 0.040
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.040
Mouse
axon guidance GO:0007411 86 0.040
positive regulation of secretion by cell GO:1903532 1 0.040
hepaticobiliary system development GO:0061008 98 0.039
digestive tract development GO:0048565 265 0.038
regulation of rna metabolic process GO:0051252 224 0.037
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.037
positive regulation of cellular process GO:0048522 201 0.037
Mouse
brain development GO:0007420 293 0.037
ion transmembrane transport GO:0034220 91 0.037
cation transport GO:0006812 81 0.037
cellular response to extracellular stimulus GO:0031668 2 0.037
heterocycle biosynthetic process GO:0018130 215 0.036
Mouse
meiotic cell cycle process GO:1903046 3 0.035
synaptic growth at neuromuscular junction GO:0051124 2 0.035
modification dependent macromolecule catabolic process GO:0043632 3 0.035
cellular response to nutrient levels GO:0031669 2 0.035
camera type eye development GO:0043010 222 0.034
autophagy GO:0006914 4 0.034
homeostatic process GO:0042592 142 0.034
meiotic chromosome segregation GO:0045132 3 0.034
organic cyclic compound metabolic process GO:1901360 301 0.034
Mouse
axon development GO:0061564 166 0.034
transmembrane transport GO:0055085 120 0.034
regulation of biosynthetic process GO:0009889 250 0.033
Mouse
establishment of localization GO:0051234 244 0.033
adult behavior GO:0030534 2 0.033
regulation of metal ion transport GO:0010959 4 0.032
small molecule metabolic process GO:0044281 77 0.032
metal ion transport GO:0030001 58 0.032
neuron projection development GO:0031175 180 0.032
blood vessel development GO:0001568 246 0.031
positive regulation of stress activated mapk cascade GO:0032874 3 0.031
glial cell migration GO:0008347 3 0.031
regulation of primary metabolic process GO:0080090 311 0.031
Mouse
i kappab kinase nf kappab signaling GO:0007249 4 0.030
tube morphogenesis GO:0035239 349 0.030
single organism transport GO:0044765 206 0.030
head development GO:0060322 303 0.030
regulation of intracellular ph GO:0051453 1 0.030
organic acid metabolic process GO:0006082 31 0.029
regulation of rna biosynthetic process GO:2001141 213 0.029
Mouse
gland development GO:0048732 143 0.029
cellular response to chemical stimulus GO:0070887 157 0.029
Mouse
digestive tract morphogenesis GO:0048546 231 0.029
heterocycle metabolic process GO:0046483 290 0.028
Mouse
somatic muscle development GO:0007525 4 0.028
heart development GO:0007507 313 0.028
regulation of nucleic acid templated transcription GO:1903506 213 0.027
Mouse
rna metabolic process GO:0016070 219 0.027
Mouse
rna biosynthetic process GO:0032774 181 0.027
Mouse
multi organism process GO:0051704 134 0.026
system process GO:0003008 185 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.026
Mouse
cellular protein metabolic process GO:0044267 129 0.026
leukocyte proliferation GO:0070661 1 0.025
hematopoietic or lymphoid organ development GO:0048534 191 0.025
immune system process GO:0002376 241 0.025
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.025
reactive oxygen species metabolic process GO:0072593 6 0.025
protein localization to plasma membrane GO:0072659 1 0.025
neurological system process GO:0050877 62 0.025
lateral inhibition GO:0046331 1 0.024
regulation of membrane potential GO:0042391 23 0.024
embryonic organ development GO:0048568 381 0.024
gastrulation with mouth forming second GO:0001702 44 0.024
regulation of circadian rhythm GO:0042752 4 0.024
determination of heart left right asymmetry GO:0061371 117 0.024
cell motility GO:0048870 244 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.023
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.023
multicellular organism growth GO:0035264 4 0.023
cellular response to organic substance GO:0071310 105 0.023
membrane repolarization GO:0086009 2 0.023
transport GO:0006810 220 0.023
sensory organ morphogenesis GO:0090596 200 0.023
positive regulation of cell cycle GO:0045787 3 0.023
positive regulation of secretion GO:0051047 1 0.022
gtp metabolic process GO:0046039 4 0.022
connective tissue development GO:0061448 99 0.022
mitochondrion organization GO:0007005 4 0.022
programmed cell death GO:0012501 119 0.022
Mouse
cellular modified amino acid metabolic process GO:0006575 3 0.022
positive regulation of catabolic process GO:0009896 4 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
alpha amino acid metabolic process GO:1901605 3 0.022
response to metal ion GO:0010038 34 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
regulation of cellular ph GO:0030641 1 0.021
anion transport GO:0006820 38 0.021
gastrulation GO:0007369 208 0.021
hindbrain development GO:0030902 91 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
Mouse
cellular amino acid metabolic process GO:0006520 7 0.021
cellular response to stress GO:0033554 62 0.021
angiogenesis GO:0001525 158 0.021
protein homooligomerization GO:0051260 3 0.020
behavior GO:0007610 74 0.020
regulation of protein transport GO:0051223 3 0.020
cellular cation homeostasis GO:0030003 17 0.020
Human Mouse
cell projection assembly GO:0030031 64 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.020
response to inorganic substance GO:0010035 38 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
multicellular organismal response to stress GO:0033555 2 0.020
macromolecular complex disassembly GO:0032984 1 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
neuron projection guidance GO:0097485 86 0.020
inorganic cation transmembrane transport GO:0098662 50 0.019
regulation of reproductive process GO:2000241 4 0.019
regulation of cytokine production GO:0001817 3 0.019
growth GO:0040007 174 0.019
cellular response to lipid GO:0071396 39 0.019
regulation of developmental process GO:0050793 247 0.019
response to transition metal nanoparticle GO:1990267 28 0.019
regulation of locomotion GO:0040012 55 0.019
carboxylic acid catabolic process GO:0046395 3 0.019
response to copper ion GO:0046688 13 0.019
regulation of gene expression GO:0010468 265 0.019
Mouse
neuroblast proliferation GO:0007405 2 0.019
developmental growth GO:0048589 166 0.019
central nervous system development GO:0007417 387 0.019
regulation of cell shape GO:0008360 1 0.019
interspecies interaction between organisms GO:0044419 4 0.019
eye development GO:0001654 277 0.019
regulation of response to nutrient levels GO:0032107 1 0.019
embryonic hemopoiesis GO:0035162 53 0.019
regulation of localization GO:0032879 104 0.018
stem cell maintenance GO:0019827 4 0.018
response to abiotic stimulus GO:0009628 122 0.018
cellular response to steroid hormone stimulus GO:0071383 31 0.018
regulation of reactive oxygen species metabolic process GO:2000377 2 0.018
alcohol biosynthetic process GO:0046165 2 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
Mouse
regulation of binding GO:0051098 3 0.018
neuronal action potential GO:0019228 18 0.018
apoptotic process involved in development GO:1902742 2 0.018
regionalization GO:0003002 274 0.018
death GO:0016265 121 0.018
Mouse
gtp catabolic process GO:0006184 2 0.018
hormone biosynthetic process GO:0042446 3 0.018
stem cell proliferation GO:0072089 4 0.017
regulation of protein catabolic process GO:0042176 1 0.017
cellular amine metabolic process GO:0044106 2 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
regulation of cell differentiation GO:0045595 142 0.017
regulation of cell projection assembly GO:0060491 4 0.017
heart morphogenesis GO:0003007 156 0.017
macromolecule localization GO:0033036 54 0.017
organelle assembly GO:0070925 110 0.017
erythrocyte homeostasis GO:0034101 55 0.017
multi organism reproductive process GO:0044703 36 0.017
response to alkaloid GO:0043279 2 0.017
response to endogenous stimulus GO:0009719 83 0.017
spermatid development GO:0007286 2 0.017
vasculature development GO:0001944 278 0.017
energy reserve metabolic process GO:0006112 2 0.017
positive regulation of signal transduction GO:0009967 56 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
myeloid cell differentiation GO:0030099 86 0.016
neurotransmitter secretion GO:0007269 2 0.016
response to lipid GO:0033993 60 0.016
transmission of nerve impulse GO:0019226 19 0.016
cellular component disassembly GO:0022411 1 0.016
cell migration GO:0016477 237 0.016
negative regulation of response to stimulus GO:0048585 104 0.016
melanin metabolic process GO:0006582 2 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
cell differentiation in spinal cord GO:0021515 40 0.016
negative regulation of cell death GO:0060548 60 0.016
Mouse
amine metabolic process GO:0009308 2 0.015
proepicardium development GO:0003342 4 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
response to topologically incorrect protein GO:0035966 2 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
lamellipodium organization GO:0097581 1 0.015
macroautophagy GO:0016236 1 0.015
protein secretion GO:0009306 1 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
membrane fusion GO:0061025 2 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
multicellular organismal reproductive process GO:0048609 35 0.015
negative regulation of cell communication GO:0010648 96 0.015
response to glucose GO:0009749 3 0.015
transition metal ion transport GO:0000041 6 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
negative regulation of kinase activity GO:0033673 4 0.015
negative regulation of cytokine production GO:0001818 1 0.015
cell substrate adhesion GO:0031589 4 0.014
negative regulation of metabolic process GO:0009892 86 0.014
organism emergence from protective structure GO:0071684 4 0.014
intracellular signal transduction GO:0035556 85 0.014
catecholamine biosynthetic process GO:0042423 2 0.014
macromolecule modification GO:0043412 111 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
spermatid differentiation GO:0048515 2 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
nuclear import GO:0051170 3 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
lipid catabolic process GO:0016042 4 0.014
organelle fusion GO:0048284 3 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
developmental programmed cell death GO:0010623 4 0.014
regulation of cell motility GO:2000145 46 0.014
endosomal transport GO:0016197 2 0.014
sexual reproduction GO:0019953 36 0.014
monovalent inorganic cation transport GO:0015672 42 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
response to other organism GO:0051707 97 0.013
cellular ketone metabolic process GO:0042180 11 0.013
rna transport GO:0050658 2 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
cellular lipid catabolic process GO:0044242 3 0.013
developmental cell growth GO:0048588 52 0.013
establishment of localization in cell GO:0051649 77 0.013
response to organic substance GO:0010033 153 0.013
proteolysis GO:0006508 38 0.013
positive regulation of protein kinase b signaling GO:0051897 1 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
Mouse
positive regulation of cell activation GO:0050867 1 0.013
digestive system development GO:0055123 289 0.013
regulation of response to stress GO:0080134 36 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.013
compound eye development GO:0048749 2 0.013
lytic vacuole organization GO:0080171 1 0.013
cellular amide metabolic process GO:0043603 4 0.013
epithelial cell differentiation GO:0030855 116 0.013
ion transport GO:0006811 114 0.013
response to external biotic stimulus GO:0043207 97 0.013
regulation of cell activation GO:0050865 1 0.013
response to biotic stimulus GO:0009607 97 0.013
chloride transport GO:0006821 8 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
myeloid cell homeostasis GO:0002262 56 0.012
bmp signaling pathway GO:0030509 52 0.012
single organism organelle organization GO:1902589 199 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
cation homeostasis GO:0055080 33 0.012
Human Mouse
action potential GO:0001508 19 0.012
regulation of immune system process GO:0002682 34 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
regulation of synapse organization GO:0050807 3 0.012
zymogen activation GO:0031638 3 0.012
multicellular organismal signaling GO:0035637 22 0.012
neurotransmitter transport GO:0006836 2 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.012
skin development GO:0043588 54 0.012
cellular component assembly GO:0022607 170 0.012
positive regulation of jnk cascade GO:0046330 3 0.012
hemopoiesis GO:0030097 183 0.012
female meiotic division GO:0007143 2 0.012
striated muscle cell differentiation GO:0051146 129 0.012
hatching GO:0035188 4 0.012
cellular response to organic cyclic compound GO:0071407 38 0.012
response to uv GO:0009411 3 0.012
septum transversum development GO:0003343 4 0.012
lamellipodium assembly GO:0030032 1 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
secondary metabolic process GO:0019748 3 0.012
heart looping GO:0001947 94 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
embryonic heart tube development GO:0035050 133 0.011
response to nutrient GO:0007584 3 0.011
outflow tract morphogenesis GO:0003151 1 0.011
lysosomal transport GO:0007041 2 0.011
fatty acid beta oxidation GO:0006635 1 0.011
cellular ion homeostasis GO:0006873 17 0.011
Human Mouse
membrane organization GO:0061024 21 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
neuromuscular process controlling balance GO:0050885 3 0.011
protein import GO:0017038 3 0.011
post embryonic organ development GO:0048569 4 0.011
somitogenesis GO:0001756 87 0.011
protein targeting to nucleus GO:0044744 3 0.011
chordate embryonic development GO:0043009 271 0.011
cell growth GO:0016049 57 0.011
cell proliferation GO:0008283 80 0.011
regulation of blood vessel size GO:0050880 2 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
oxoacid metabolic process GO:0043436 31 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
Mouse
photoreceptor cell fate commitment GO:0046552 1 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
response to oxygen containing compound GO:1901700 55 0.011
protein stabilization GO:0050821 2 0.011
actin mediated cell contraction GO:0070252 1 0.011
single organism nuclear import GO:1902593 3 0.010
germ line stem cell maintenance GO:0030718 2 0.010
photoreceptor cell fate specification GO:0043704 1 0.010
chemical homeostasis GO:0048878 49 0.010
Human Mouse
polyol metabolic process GO:0019751 1 0.010
sulfate transmembrane transport GO:1902358 2 0.010
response to light stimulus GO:0009416 46 0.010
protein complex disassembly GO:0043241 1 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
cytoskeleton organization GO:0007010 96 0.010
respiratory electron transport chain GO:0022904 2 0.010
nucleic acid transport GO:0050657 2 0.010
primary neural tube formation GO:0014020 1 0.010
metal ion homeostasis GO:0055065 26 0.010
Human Mouse
embryonic heart tube morphogenesis GO:0003143 108 0.010

slc40a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
disease of metabolism DOID:0014667 0 0.018
Human
inherited metabolic disorder DOID:655 0 0.018
Human
nervous system disease DOID:863 0 0.016