Danio rerio

0 known processes

slc6a5

solute carrier family 6 (neurotransmitter transporter, glycine), member 5

(Aliases: glyt2,si:dkey-7n10.12)

slc6a5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amino acid transport GO:0006865 2 0.289
Zebrafish
neuron neuron synaptic transmission GO:0007270 1 0.279
Zebrafish
anion transport GO:0006820 38 0.216
Zebrafish
monoamine transport GO:0015844 1 0.214
Zebrafish
single organism localization GO:1902578 225 0.166
Zebrafish
neurotransmitter transport GO:0006836 2 0.155
brain development GO:0007420 293 0.140
regulation of biological quality GO:0065008 263 0.135
Zebrafish
organic anion transport GO:0015711 15 0.096
Zebrafish
positive regulation of transport GO:0051050 2 0.088
transport GO:0006810 220 0.082
Zebrafish
negative regulation of metabolic process GO:0009892 86 0.080
membrane hyperpolarization GO:0060081 1 0.075
Zebrafish
single organism transport GO:0044765 206 0.075
Zebrafish
larval development GO:0002164 2 0.074
dicarboxylic acid transport GO:0006835 1 0.069
response to vitamin GO:0033273 3 0.067
hormone transport GO:0009914 2 0.066
cognition GO:0050890 1 0.063
gene expression GO:0010467 252 0.062
negative regulation of cellular process GO:0048523 283 0.062
response to drug GO:0042493 3 0.062
cellular macromolecule metabolic process GO:0044260 391 0.061
digestive system development GO:0055123 289 0.057
cellular response to external stimulus GO:0071496 2 0.056
response to nutrient GO:0007584 3 0.055
cell cell signaling GO:0007267 52 0.055
Zebrafish
small molecule catabolic process GO:0044282 3 0.054
neuron differentiation GO:0030182 353 0.054
negative regulation of biological process GO:0048519 304 0.053
locomotory behavior GO:0007626 34 0.051
Zebrafish
positive regulation of cellular process GO:0048522 201 0.050
regulation of signaling GO:0023051 235 0.049
Zebrafish
aging GO:0007568 2 0.049
response to chemical GO:0042221 320 0.048
regulation of primary metabolic process GO:0080090 311 0.047
nucleic acid metabolic process GO:0090304 244 0.047
digestive tract development GO:0048565 265 0.044
regulation of inflammatory response GO:0050727 2 0.044
head development GO:0060322 303 0.043
cellular biosynthetic process GO:0044249 286 0.042
peptidyl serine phosphorylation GO:0018105 1 0.041
adult behavior GO:0030534 2 0.041
nuclear transport GO:0051169 4 0.039
regulation of cytokine production GO:0001817 3 0.039
central nervous system development GO:0007417 387 0.039
embryonic organ development GO:0048568 381 0.039
generation of neurons GO:0048699 385 0.038
sensory organ development GO:0007423 393 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
regulation of protein transport GO:0051223 3 0.038
cellular amino acid biosynthetic process GO:0008652 2 0.038
positive regulation of cell cycle GO:0045787 3 0.037
nitrogen compound transport GO:0071705 23 0.037
Zebrafish
establishment of localization GO:0051234 244 0.037
Zebrafish
regulation of hormone secretion GO:0046883 2 0.037
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.036
cellular protein modification process GO:0006464 100 0.036
regulation of multicellular organismal process GO:0051239 277 0.036
neurological system process GO:0050877 62 0.035
eye development GO:0001654 277 0.035
endocrine process GO:0050886 2 0.035
regulation of cell communication GO:0010646 232 0.034
Zebrafish
camera type eye development GO:0043010 222 0.034
oxoacid metabolic process GO:0043436 31 0.033
positive regulation of metabolic process GO:0009893 108 0.033
organic substance biosynthetic process GO:1901576 289 0.032
heterocycle metabolic process GO:0046483 290 0.032
response to abiotic stimulus GO:0009628 122 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
astrocyte differentiation GO:0048708 1 0.032
erythrocyte differentiation GO:0030218 54 0.032
response to stress GO:0006950 263 0.031
regulation of multicellular organismal development GO:2000026 223 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
heterocycle biosynthetic process GO:0018130 215 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.030
regulation of cellular metabolic process GO:0031323 320 0.030
carboxylic acid catabolic process GO:0046395 3 0.030
cell differentiation in spinal cord GO:0021515 40 0.030
organic acid catabolic process GO:0016054 3 0.030
organic cyclic compound metabolic process GO:1901360 301 0.029
protein acetylation GO:0006473 2 0.029
cellular aromatic compound metabolic process GO:0006725 295 0.029
alpha amino acid metabolic process GO:1901605 3 0.029
behavior GO:0007610 74 0.029
Zebrafish
ion transport GO:0006811 114 0.029
Zebrafish
protein secretion GO:0009306 1 0.027
regulation of protein localization to nucleus GO:1900180 2 0.027
protein localization to nucleus GO:0034504 3 0.027
positive regulation of secretion GO:0051047 1 0.027
neuron development GO:0048666 262 0.027
regulation of gene expression GO:0010468 265 0.027
neurotransmitter secretion GO:0007269 2 0.027
gastrulation GO:0007369 208 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.026
cellular component morphogenesis GO:0032989 336 0.026
tube morphogenesis GO:0035239 349 0.026
macromolecule modification GO:0043412 111 0.026
regulation of response to stimulus GO:0048583 269 0.026
regulation of macromolecule biosynthetic process GO:0010556 225 0.026
negative regulation of dna metabolic process GO:0051053 4 0.026
response to hexose GO:0009746 3 0.026
multicellular organism growth GO:0035264 4 0.026
regulation of dendrite development GO:0050773 3 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
myeloid cell differentiation GO:0030099 86 0.025
cellular protein metabolic process GO:0044267 129 0.025
regulation of reproductive process GO:2000241 4 0.025
amine metabolic process GO:0009308 2 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.024
liver development GO:0001889 96 0.024
erythrocyte homeostasis GO:0034101 55 0.024
blood vessel development GO:0001568 246 0.024
peptide transport GO:0015833 1 0.024
positive regulation of biological process GO:0048518 253 0.024
hormone secretion GO:0046879 2 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
regulation of binding GO:0051098 3 0.024
digestive tract morphogenesis GO:0048546 231 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
regulation of metal ion transport GO:0010959 4 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
mechanosensory lateral line system development GO:0048881 49 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
regulation of rna biosynthetic process GO:2001141 213 0.023
proteasomal protein catabolic process GO:0010498 2 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
hepaticobiliary system development GO:0061008 98 0.023
chordate embryonic development GO:0043009 271 0.023
cellular protein catabolic process GO:0044257 4 0.023
cell projection organization GO:0030030 284 0.023
system process GO:0003008 185 0.022
epithelial cell differentiation GO:0030855 116 0.022
protein acylation GO:0043543 3 0.022
organic substance transport GO:0071702 58 0.022
Zebrafish
positive regulation of catabolic process GO:0009896 4 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
immune system process GO:0002376 241 0.022
protein import into nucleus GO:0006606 3 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
response to metal ion GO:0010038 34 0.022
signal transduction GO:0007165 455 0.022
gtp catabolic process GO:0006184 2 0.022
regulation of dna recombination GO:0000018 2 0.022
determination of left right symmetry GO:0007368 179 0.022
myeloid cell homeostasis GO:0002262 56 0.022
guanosine containing compound catabolic process GO:1901069 2 0.021
phosphorylation GO:0016310 69 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
central nervous system neuron differentiation GO:0021953 74 0.021
regulation of transcription dna templated GO:0006355 213 0.021
somatic muscle development GO:0007525 4 0.021
determination of bilateral symmetry GO:0009855 204 0.021
hemopoiesis GO:0030097 183 0.021
response to alkaloid GO:0043279 2 0.021
protein metabolic process GO:0019538 183 0.021
carboxylic acid transport GO:0046942 8 0.020
Zebrafish
biosynthetic process GO:0009058 294 0.020
organic acid transport GO:0015849 9 0.020
Zebrafish
single organism membrane fusion GO:0044801 2 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
cell part morphogenesis GO:0032990 246 0.020
vasculature development GO:0001944 278 0.020
response to wounding GO:0009611 116 0.020
regulation of developmental process GO:0050793 247 0.020
cell fate commitment GO:0045165 99 0.020
regulation of gtp catabolic process GO:0033124 2 0.020
nuclear import GO:0051170 3 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.020
protein targeting to nucleus GO:0044744 3 0.020
growth GO:0040007 174 0.020
regulation of blood pressure GO:0008217 1 0.020
response to nicotine GO:0035094 2 0.020
regulation of neurotransmitter secretion GO:0046928 1 0.019
eye morphogenesis GO:0048592 144 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
regulation of circadian rhythm GO:0042752 4 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.019
ventral spinal cord development GO:0021517 35 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
regulation of synapse assembly GO:0051963 3 0.018
regulation of sodium ion transport GO:0002028 2 0.018
response to mechanical stimulus GO:0009612 24 0.018
regulation of apoptotic process GO:0042981 98 0.018
synaptic transmission glycinergic GO:0060012 1 0.018
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.018
mitochondrion organization GO:0007005 4 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
chemosensory behavior GO:0007635 1 0.018
single organism biosynthetic process GO:0044711 71 0.018
response to inorganic substance GO:0010035 38 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of cell differentiation GO:0045595 142 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
neuron projection morphogenesis GO:0048812 161 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
negative regulation of reproductive process GO:2000242 3 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
regulation of cellular component organization GO:0051128 86 0.018
regulation of synapse organization GO:0050807 3 0.018
organic acid metabolic process GO:0006082 31 0.018
locomotor rhythm GO:0045475 3 0.017
regulation of neurotransmitter transport GO:0051588 1 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
muscle structure development GO:0061061 196 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
positive regulation of cytokine production GO:0001819 2 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
cellular component biogenesis GO:0044085 178 0.017
maintenance of location GO:0051235 4 0.017
protein localization GO:0008104 40 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
response to glucose GO:0009749 3 0.017
determination of heart left right asymmetry GO:0061371 117 0.017
heart looping GO:0001947 94 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
lateral inhibition GO:0046331 1 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
sleep GO:0030431 1 0.017
regulation of blood vessel size GO:0050880 2 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
single organism nuclear import GO:1902593 3 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
lipid storage GO:0019915 1 0.016
homeostasis of number of cells GO:0048872 62 0.016
homeostatic process GO:0042592 142 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
negative regulation of kinase activity GO:0033673 4 0.016
response to monosaccharide GO:0034284 3 0.016
stem cell maintenance GO:0019827 4 0.016
embryonic hemopoiesis GO:0035162 53 0.016
regulation of embryonic development GO:0045995 47 0.016
secondary metabolic process GO:0019748 3 0.016
regulation of protein complex assembly GO:0043254 3 0.016
macromolecule localization GO:0033036 54 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
neuron projection development GO:0031175 180 0.016
spinal cord development GO:0021510 46 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
cell proliferation GO:0008283 80 0.016
single organism metabolic process GO:0044710 217 0.015
regulation of metabolic process GO:0019222 359 0.015
mechanosensory behavior GO:0007638 2 0.015
protein import GO:0017038 3 0.015
lateral line development GO:0048882 66 0.015
regulation of postsynaptic membrane potential GO:0060078 1 0.015
Zebrafish
primitive hemopoiesis GO:0060215 27 0.015
reactive oxygen species biosynthetic process GO:1903409 1 0.015
heart development GO:0007507 313 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
cellular response to nutrient levels GO:0031669 2 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
b cell mediated immunity GO:0019724 3 0.015
gtp metabolic process GO:0046039 4 0.015
regulation of protein catabolic process GO:0042176 1 0.015
negative regulation of secretion GO:0051048 2 0.015
protein modification process GO:0036211 100 0.015
localization of cell GO:0051674 244 0.015
nuclear export GO:0051168 1 0.015
pancreas development GO:0031016 84 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
negative regulation of catabolic process GO:0009895 3 0.015
response to external stimulus GO:0009605 264 0.015
cell morphogenesis GO:0000902 289 0.015
regulation of rna metabolic process GO:0051252 224 0.015
reactive oxygen species metabolic process GO:0072593 6 0.015
response to hydrogen peroxide GO:0042542 3 0.015
regulation of protein metabolic process GO:0051246 56 0.015
positive regulation of chromosome organization GO:2001252 1 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.014
phagocytosis GO:0006909 3 0.014
small molecule metabolic process GO:0044281 77 0.014
positive regulation of epithelial cell differentiation GO:0030858 2 0.014
posterior lateral line system development GO:0048915 46 0.014
cellular localization GO:0051641 97 0.014
spinal cord motor neuron differentiation GO:0021522 26 0.014
nephron morphogenesis GO:0072028 2 0.014
regulation of molecular function GO:0065009 70 0.014
blood vessel morphogenesis GO:0048514 216 0.014
endocrine hormone secretion GO:0060986 2 0.014
regulation of muscle hypertrophy GO:0014743 2 0.014
angiogenesis GO:0001525 158 0.014
appendage development GO:0048736 80 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
fertilization GO:0009566 3 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.013
response to lipid GO:0033993 60 0.013
regulation of protein targeting GO:1903533 2 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
autophagy GO:0006914 4 0.013
establishment of localization in cell GO:0051649 77 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
organic hydroxy compound transport GO:0015850 14 0.013
Zebrafish
cellular response to oxygen levels GO:0071453 1 0.013
negative regulation of protein transport GO:0051224 3 0.013
regeneration GO:0031099 91 0.013
vestibular reflex GO:0060005 2 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
transmembrane transport GO:0055085 120 0.013
Zebrafish
protein phosphorylation GO:0006468 47 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
single fertilization GO:0007338 3 0.013
meiotic nuclear division GO:0007126 4 0.013
transcription dna templated GO:0006351 181 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
dicarboxylic acid metabolic process GO:0043648 1 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
larval behavior GO:0030537 5 0.013
cell projection morphogenesis GO:0048858 244 0.013
peptidyl serine modification GO:0018209 2 0.013
regulation of neurotransmitter levels GO:0001505 5 0.012
single organism behavior GO:0044708 24 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
retina layer formation GO:0010842 24 0.012
response to heat GO:0009408 6 0.012
cellular response to starvation GO:0009267 1 0.012
negative regulation of hormone secretion GO:0046888 2 0.012
taxis GO:0042330 109 0.012
nitric oxide metabolic process GO:0046209 2 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
death GO:0016265 121 0.012
sensory perception GO:0007600 39 0.012
regulation of protein binding GO:0043393 3 0.012
regulation of signal transduction GO:0009966 225 0.012
regulation of catalytic activity GO:0050790 55 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of glial cell differentiation GO:0045685 4 0.012
l amino acid transport GO:0015807 1 0.012
Zebrafish
apoptotic process GO:0006915 116 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
positive regulation of multi organism process GO:0043902 3 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
heart process GO:0003015 71 0.012
catecholamine metabolic process GO:0006584 2 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of organ morphogenesis GO:2000027 35 0.012
positive regulation of cell division GO:0051781 2 0.011
response to biotic stimulus GO:0009607 97 0.011
neuron projection regeneration GO:0031102 16 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of multicellular organism growth GO:0040014 4 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
cell growth GO:0016049 57 0.011
response to cadmium ion GO:0046686 14 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
regulation of biosynthetic process GO:0009889 250 0.011
leukocyte proliferation GO:0070661 1 0.011
synapse assembly GO:0007416 9 0.011
rna metabolic process GO:0016070 219 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
cellular amine metabolic process GO:0044106 2 0.011
regulation of circadian sleep wake cycle GO:0042749 1 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
regulation of calcium ion transport GO:0051924 2 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
negative regulation of gliogenesis GO:0014014 1 0.011
regulation of hormone levels GO:0010817 21 0.011
organelle organization GO:0006996 227 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
cellular ketone metabolic process GO:0042180 11 0.011
larval locomotory behavior GO:0008345 5 0.011
synaptic vesicle localization GO:0097479 1 0.011
alcohol biosynthetic process GO:0046165 2 0.011
positive regulation of cell communication GO:0010647 56 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
cell motility GO:0048870 244 0.011
skeletal system morphogenesis GO:0048705 102 0.011
sensory organ morphogenesis GO:0090596 200 0.011
developmental programmed cell death GO:0010623 4 0.010
exocytosis GO:0006887 1 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
response to oxidative stress GO:0006979 11 0.010
tissue remodeling GO:0048771 4 0.010
cellular component assembly GO:0022607 170 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
neuromuscular process controlling balance GO:0050885 3 0.010
circadian sleep wake cycle GO:0042745 2 0.010
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
regulation of gtpase activity GO:0043087 2 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
regulation of endothelial cell proliferation GO:0001936 1 0.010
multicellular organismal metabolic process GO:0044236 2 0.010
regulation of neurological system process GO:0031644 2 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
positive regulation of neuron death GO:1901216 1 0.010
positive regulation of lipid metabolic process GO:0045834 1 0.010
positive regulation of neural precursor cell proliferation GO:2000179 1 0.010
response to axon injury GO:0048678 14 0.010

slc6a5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.015
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
nervous system disease DOID:863 0 0.012
eye disease DOID:5614 0 0.012