Danio rerio

129 known processes

slit2

slit (Drosophila) homolog 2

slit2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of axon guidance GO:1902668 1 0.661
Human Worm
cell motility GO:0048870 244 0.589
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.572
Worm
anterior posterior axon guidance GO:0033564 5 0.535
embryonic organ development GO:0048568 381 0.512
Fly
negative regulation of synapse assembly GO:0051964 2 0.457
Zebrafish
chemotaxis GO:0006935 104 0.364
morphogenesis of an epithelium GO:0002009 333 0.360
central nervous system development GO:0007417 387 0.358
olfactory lobe development GO:0021988 4 0.358
Human Mouse
generation of neurons GO:0048699 385 0.331
cell migration to the midline involved in heart development GO:0003318 12 0.314
cellular macromolecule metabolic process GO:0044260 391 0.303
Human
axonal defasciculation GO:0007414 2 0.290
tissue migration GO:0090130 37 0.285
Human Fly
localization of cell GO:0051674 244 0.283
regulation of synapse organization GO:0050807 3 0.273
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.271
negative regulation of chemotaxis GO:0050922 4 0.264
Human Rat Worm
central nervous system neuron differentiation GO:0021953 74 0.261
cellular nitrogen compound biosynthetic process GO:0044271 218 0.249
regulation of biological quality GO:0065008 263 0.226
cell projection organization GO:0030030 284 0.214
forebrain cell migration GO:0021885 1 0.213
Human Mouse
ameboidal type cell migration GO:0001667 143 0.212
Human Fly
regulation of synapse assembly GO:0051963 3 0.196
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.195
Human Mouse
regulation of apoptotic process GO:0042981 98 0.187
Human
retinal ganglion cell axon guidance GO:0031290 35 0.176
Human Mouse
outflow tract morphogenesis GO:0003151 1 0.170
Fly
cell migration involved in gastrulation GO:0042074 79 0.169
Fly
negative regulation of axon extension GO:0030517 7 0.166
stem cell differentiation GO:0048863 117 0.161
negative regulation of protein phosphorylation GO:0001933 4 0.160
Human
cell migration GO:0016477 237 0.159
regulation of cell shape GO:0008360 1 0.153
regulation of cell motility GO:2000145 46 0.150
Human Rat Fly
positive regulation of cell adhesion GO:0045785 1 0.148
Fly
larval development GO:0002164 2 0.143
intracellular signal transduction GO:0035556 85 0.142
Human
cellular biosynthetic process GO:0044249 286 0.140
olfactory bulb development GO:0021772 4 0.134
Human Mouse
sensory organ development GO:0007423 393 0.134
single organism localization GO:1902578 225 0.128
axon development GO:0061564 166 0.126
positive regulation of neuron projection development GO:0010976 9 0.125
Zebrafish
lateral inhibition GO:0046331 1 0.121
Fly
regionalization GO:0003002 274 0.121
Fly
regulation of cell communication GO:0010646 232 0.120
Human
cellular component movement GO:0006928 335 0.120
synaptic growth at neuromuscular junction GO:0051124 2 0.116
head development GO:0060322 303 0.116
Human Mouse Rat
regulation of cell development GO:0060284 100 0.110
exocrine system development GO:0035272 28 0.109
Fly
cell surface receptor signaling pathway GO:0007166 325 0.109
Human Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.108
response to chemical GO:0042221 320 0.106
embryonic organ morphogenesis GO:0048562 274 0.105
cell substrate adhesion GO:0031589 4 0.104
rna biosynthetic process GO:0032774 181 0.103
neuron differentiation GO:0030182 353 0.100
positive regulation of transport GO:0051050 2 0.099
single organism transport GO:0044765 206 0.098
positive regulation of cell cycle GO:0045787 3 0.097
axon guidance GO:0007411 86 0.096
regulation of cell size GO:0008361 29 0.096
axon midline choice point recognition GO:0016199 4 0.096
Fly
programmed cell death GO:0012501 119 0.095
Human
skeletal system morphogenesis GO:0048705 102 0.094
negative regulation of behavior GO:0048521 6 0.093
Human Rat Worm
locomotion GO:0040011 313 0.093
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.093
odontogenesis of dentin containing tooth GO:0042475 1 0.092
regulation of signaling GO:0023051 235 0.092
Human
cellular component biogenesis GO:0044085 178 0.091
Human Zebrafish
locomotory behavior GO:0007626 34 0.089
central nervous system neuron development GO:0021954 29 0.089
regulation of axon guidance GO:1902667 8 0.089
Human Worm
tube morphogenesis GO:0035239 349 0.088
Human Mouse Fly
regulation of axon extension GO:0030516 24 0.085
organic cyclic compound metabolic process GO:1901360 301 0.084
Human
signal transduction GO:0007165 455 0.083
Human Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.083
cellular nitrogen compound metabolic process GO:0034641 290 0.082
Human
camera type eye development GO:0043010 222 0.082
regulation of multicellular organismal development GO:2000026 223 0.082
regulation of reproductive process GO:2000241 4 0.080
establishment of synaptic vesicle localization GO:0097480 1 0.079
regulation of neurogenesis GO:0050767 87 0.079
positive regulation of biological process GO:0048518 253 0.076
Human Zebrafish Fly
regulation of binding GO:0051098 3 0.075
eye development GO:0001654 277 0.075
regulation of response to cytokine stimulus GO:0060759 3 0.075
Human
cell migration involved in heart formation GO:0060974 10 0.074
regulation of tube size GO:0035150 2 0.074
regulation of response to stimulus GO:0048583 269 0.074
Human Rat Worm Fly
cellular carbohydrate metabolic process GO:0044262 4 0.072
regulation of signal transduction GO:0009966 225 0.072
Human
negative regulation of cellular process GO:0048523 283 0.072
fertilization GO:0009566 3 0.072
regulation of glial cell differentiation GO:0045685 4 0.072
neuron projection morphogenesis GO:0048812 161 0.070
regulation of primary metabolic process GO:0080090 311 0.070
Human
developmental growth GO:0048589 166 0.070
cell growth GO:0016049 57 0.070
neuron development GO:0048666 262 0.070
negative regulation of biological process GO:0048519 304 0.069
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.067
Human Worm
positive regulation of cell projection organization GO:0031346 9 0.066
Zebrafish
heterocycle metabolic process GO:0046483 290 0.064
Human
gland development GO:0048732 143 0.064
Mouse Fly
regulation of cell differentiation GO:0045595 142 0.063
behavior GO:0007610 74 0.062
Human Rat Worm Fly
central nervous system neuron axonogenesis GO:0021955 18 0.062
regulation of cell cell adhesion GO:0022407 13 0.062
Fly
convergent extension GO:0060026 118 0.061
regulation of epithelial cell proliferation GO:0050678 3 0.061
brain development GO:0007420 293 0.061
Human Mouse Rat
mesodermal cell migration GO:0008078 12 0.061
Fly
digestive tract morphogenesis GO:0048546 231 0.061
Fly
stem cell maintenance GO:0019827 4 0.061
negative regulation of developmental process GO:0051093 65 0.059
cellular component morphogenesis GO:0032989 336 0.059
response to stress GO:0006950 263 0.058
Rat
regulation of localization GO:0032879 104 0.058
Human Rat Worm Fly
negative regulation of neuron projection development GO:0010977 9 0.058
cell morphogenesis involved in differentiation GO:0000904 195 0.057
developmental growth involved in morphogenesis GO:0060560 86 0.057
neuron projection development GO:0031175 180 0.057
muscle structure development GO:0061061 196 0.057
positive regulation of reproductive process GO:2000243 2 0.057
neuroblast proliferation GO:0007405 2 0.057
regulation of organelle organization GO:0033043 29 0.057
Human
establishment of organelle localization GO:0051656 45 0.056
cranial nerve morphogenesis GO:0021602 15 0.056
establishment of localization GO:0051234 244 0.056
regulation of locomotion GO:0040012 55 0.055
Human Rat Worm Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.055
response to monosaccharide GO:0034284 3 0.055
determination of ventral identity GO:0048264 21 0.055
neuron recognition GO:0008038 18 0.055
epithelial cell migration GO:0010631 25 0.054
Human Fly
response to organic substance GO:0010033 153 0.054
Human
nucleic acid templated transcription GO:0097659 181 0.053
positive regulation of epithelial cell proliferation GO:0050679 1 0.053
apoptotic process GO:0006915 116 0.053
Human
embryonic heart tube development GO:0035050 133 0.053
Fly
epithelial tube morphogenesis GO:0060562 148 0.053
Human Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.052
medulla oblongata development GO:0021550 4 0.052
response to external stimulus GO:0009605 264 0.052
response to organic cyclic compound GO:0014070 51 0.051
Human
heterocycle biosynthetic process GO:0018130 215 0.050
negative regulation of growth GO:0045926 10 0.050
nucleobase containing compound metabolic process GO:0006139 274 0.050
Human
stem cell development GO:0048864 82 0.050
regulation of cell death GO:0010941 103 0.050
Human
regulation of cellular component movement GO:0051270 55 0.049
Human Rat Worm Fly
renal system development GO:0072001 94 0.048
Human Mouse
central nervous system projection neuron axonogenesis GO:0021952 15 0.048
extrinsic apoptotic signaling pathway GO:0097191 3 0.048
regulation of programmed cell death GO:0043067 101 0.048
Human
glial cell migration GO:0008347 3 0.048
Fly
regulation of cell projection organization GO:0031344 44 0.048
vasculature development GO:0001944 278 0.048
Human
negative regulation of response to cytokine stimulus GO:0060761 2 0.048
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.047
regulation of stem cell differentiation GO:2000736 4 0.047
urogenital system development GO:0001655 97 0.047
Human Mouse
response to hexose GO:0009746 3 0.047
mesoderm development GO:0007498 88 0.047
Fly
transcription dna templated GO:0006351 181 0.047
regulation of transcription dna templated GO:0006355 213 0.047
negative regulation of axonogenesis GO:0050771 7 0.047
apoptotic process involved in development GO:1902742 2 0.046
Human
cognition GO:0050890 1 0.045
cell migration involved in heart development GO:0060973 22 0.045
response to carbohydrate GO:0009743 3 0.045
regulation of biosynthetic process GO:0009889 250 0.045
neuron projection guidance GO:0097485 86 0.045
cellular response to chemical stimulus GO:0070887 157 0.045
Human Rat
positive regulation of cell development GO:0010720 25 0.044
Zebrafish
cell death GO:0008219 121 0.044
Human
gastrulation GO:0007369 208 0.044
Fly
blood vessel development GO:0001568 246 0.044
Human
negative regulation of developmental growth GO:0048640 9 0.043
regulation of neuron differentiation GO:0045664 56 0.043
protein modification process GO:0036211 100 0.043
Human
digestive system development GO:0055123 289 0.043
Fly
regulation of chemotaxis GO:0050920 18 0.043
Human Rat Worm Fly
positive regulation of cellular process GO:0048522 201 0.042
Human Zebrafish Fly
mesenchyme development GO:0060485 127 0.042
regulation of multicellular organism growth GO:0040014 4 0.042
positive regulation of cellular component biogenesis GO:0044089 3 0.042
regulation of axon extension involved in axon guidance GO:0048841 6 0.041
Worm
cellular amine metabolic process GO:0044106 2 0.041
regulation of axonogenesis GO:0050770 32 0.041
synaptic vesicle transport GO:0048489 1 0.041
synapse organization GO:0050808 21 0.040
Zebrafish
regulation of intracellular signal transduction GO:1902531 57 0.040
Human
heart morphogenesis GO:0003007 156 0.040
epithelium migration GO:0090132 25 0.040
Human Fly
response to nutrient GO:0007584 3 0.040
skeletal system development GO:0001501 181 0.040
blood vessel morphogenesis GO:0048514 216 0.039
Human
regulation of developmental process GO:0050793 247 0.039
cell morphogenesis GO:0000902 289 0.039
organelle organization GO:0006996 227 0.039
Human
death GO:0016265 121 0.039
Human
small molecule metabolic process GO:0044281 77 0.039
Human
endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262 4 0.038
positive regulation of map kinase activity GO:0043406 3 0.038
histone deacetylation GO:0016575 2 0.037
cell fate commitment GO:0045165 99 0.037
Fly
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.037
regulation of cellular metabolic process GO:0031323 320 0.037
Human
negative regulation of multicellular organismal process GO:0051241 69 0.037
regulation of multicellular organismal process GO:0051239 277 0.037
negative regulation of response to stimulus GO:0048585 104 0.036
Human Rat Worm
embryonic cranial skeleton morphogenesis GO:0048701 90 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.036
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.036
cellular response to external stimulus GO:0071496 2 0.035
positive regulation of cell division GO:0051781 2 0.035
response to external biotic stimulus GO:0043207 97 0.035
regulation of epithelial to mesenchymal transition GO:0010717 3 0.035
nucleus localization GO:0051647 8 0.035
stem cell proliferation GO:0072089 4 0.034
regulation of extent of cell growth GO:0061387 29 0.034
nucleobase containing compound biosynthetic process GO:0034654 205 0.034
response to glucose GO:0009749 3 0.034
motor neuron axon guidance GO:0008045 23 0.034
Human
positive regulation of developmental process GO:0051094 50 0.034
Zebrafish
regulation of mrna processing GO:0050684 3 0.034
regulation of chondrocyte differentiation GO:0032330 1 0.034
taxis GO:0042330 109 0.033
sensory neuron axon guidance GO:0097374 3 0.033
response to glucocorticoid GO:0051384 1 0.033
Human
protein metabolic process GO:0019538 183 0.033
Human
positive regulation of response to stimulus GO:0048584 80 0.033
Human Fly
mesenchymal cell development GO:0014031 78 0.033
synaptic target recognition GO:0008039 1 0.033
cell projection morphogenesis GO:0048858 244 0.032
branchiomotor neuron axon guidance GO:0021785 1 0.032
negative regulation of apoptotic process GO:0043066 55 0.032
neural crest cell development GO:0014032 62 0.032
negative regulation of locomotion GO:0040013 18 0.032
Human Rat Worm
regulation of protein localization to nucleus GO:1900180 2 0.032
embryonic skeletal system morphogenesis GO:0048704 93 0.032
skeletal muscle organ development GO:0060538 78 0.032
protein localization to nucleus GO:0034504 3 0.032
maintenance of location GO:0051235 4 0.031
synaptic vesicle recycling GO:0036465 1 0.031
heart development GO:0007507 313 0.031
response to other organism GO:0051707 97 0.031
anatomical structure arrangement GO:0048532 2 0.031
transport GO:0006810 220 0.031
camera type eye morphogenesis GO:0048593 108 0.031
regulation of gene expression GO:0010468 265 0.030
Mouse
synaptic vesicle localization GO:0097479 1 0.030
regulation of blood vessel size GO:0050880 2 0.030
response to drug GO:0042493 3 0.030
regulation of system process GO:0044057 40 0.030
signal transduction in absence of ligand GO:0038034 1 0.030
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.030
regulation of neuron projection regeneration GO:0070570 7 0.030
nucleocytoplasmic transport GO:0006913 4 0.029
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.029
positive regulation of cellular component organization GO:0051130 13 0.029
Zebrafish
primary neural tube formation GO:0014020 1 0.029
negative regulation of cell growth GO:0030308 7 0.029
cellular protein modification process GO:0006464 100 0.029
Human
regulation of nucleoside metabolic process GO:0009118 2 0.028
muscle cell migration GO:0014812 4 0.028
Human
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.028
odontogenesis GO:0042476 9 0.028
phosphate containing compound metabolic process GO:0006796 108 0.028
Human
response to mechanical stimulus GO:0009612 24 0.028
specification of symmetry GO:0009799 204 0.028
developmental cell growth GO:0048588 52 0.028
system process GO:0003008 185 0.028
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
nucleic acid metabolic process GO:0090304 244 0.028
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.027
adult behavior GO:0030534 2 0.027
negative regulation of gliogenesis GO:0014014 1 0.027
adherens junction organization GO:0034332 4 0.027
cell part morphogenesis GO:0032990 246 0.027
positive regulation of neurogenesis GO:0050769 24 0.027
Zebrafish
positive regulation of stress activated mapk cascade GO:0032874 3 0.027
reactive nitrogen species metabolic process GO:2001057 0 0.027
regulation of collateral sprouting in absence of injury GO:0048696 4 0.027
kidney development GO:0001822 92 0.027
Human Mouse
cell proliferation GO:0008283 80 0.027
Mouse
eye morphogenesis GO:0048592 144 0.027
rna metabolic process GO:0016070 219 0.026
regulation of protein binding GO:0043393 3 0.026
somatic muscle development GO:0007525 4 0.026
negative regulation of cell death GO:0060548 60 0.026
regulation of carbohydrate metabolic process GO:0006109 4 0.026
digestive tract mesoderm development GO:0007502 1 0.025
Fly
establishment of localization in cell GO:0051649 77 0.025
cartilage development GO:0051216 96 0.025
mesoderm formation GO:0001707 43 0.025
Fly
negative regulation of signal transduction GO:0009968 94 0.025
Human
biological adhesion GO:0022610 40 0.025
Mouse Fly
cranial nerve development GO:0021545 42 0.025
positive regulation of dna metabolic process GO:0051054 1 0.025
immune system process GO:0002376 241 0.024
Human Rat
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.024
single organism metabolic process GO:0044710 217 0.024
Human
phosphorylation GO:0016310 69 0.024
Human
regulation of organ morphogenesis GO:2000027 35 0.024
response to vitamin GO:0033273 3 0.024
regulation of catalytic activity GO:0050790 55 0.024
Human
carbohydrate homeostasis GO:0033500 1 0.024
ovulation cycle process GO:0022602 2 0.024
Human
growth GO:0040007 174 0.024
nephron tubule morphogenesis GO:0072078 1 0.024
female gonad development GO:0008585 4 0.024
Human
regulation of cellular component size GO:0032535 30 0.024
protein import into nucleus GO:0006606 3 0.024
positive regulation of rna biosynthetic process GO:1902680 57 0.024
convergent extension involved in gastrulation GO:0060027 71 0.023
regulation of cellular component organization GO:0051128 86 0.023
organic substance transport GO:0071702 58 0.023
multi organism process GO:0051704 134 0.023
ovulation cycle GO:0042698 2 0.023
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
gene expression GO:0010467 252 0.023
Mouse
pericardium development GO:0060039 1 0.023
erk1 and erk2 cascade GO:0070371 4 0.023
dorsal convergence GO:0060030 14 0.023
positive regulation of nucleic acid templated transcription GO:1903508 57 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
Human
positive regulation of molecular function GO:0044093 33 0.023
monoamine transport GO:0015844 1 0.023
positive regulation of secretion GO:0051047 1 0.022
multi organism cellular process GO:0044764 2 0.022
neuron migration GO:0001764 22 0.022
Worm Fly
negative regulation of phosphate metabolic process GO:0045936 13 0.022
Human
single organismal cell cell adhesion GO:0016337 29 0.022
Mouse Fly
positive regulation of nervous system development GO:0051962 25 0.022
Zebrafish
multicellular organismal signaling GO:0035637 22 0.022
negative regulation of cell projection organization GO:0031345 9 0.022
regeneration GO:0031099 91 0.022
response to ketone GO:1901654 1 0.022
Human
negative regulation of protein kinase activity GO:0006469 4 0.022
oxoacid metabolic process GO:0043436 31 0.022
response to alkaloid GO:0043279 2 0.022
macromolecule deacylation GO:0098732 3 0.022
cellular component disassembly GO:0022411 1 0.022
amine metabolic process GO:0009308 2 0.022
positive regulation of secretion by cell GO:1903532 1 0.021
regulation of cell migration GO:0030334 40 0.021
Human Rat Fly
cellular response to organic substance GO:0071310 105 0.021
Human
organonitrogen compound metabolic process GO:1901564 74 0.021
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.021
embryonic viscerocranium morphogenesis GO:0048703 52 0.021
response to biotic stimulus GO:0009607 97 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
neuron neuron synaptic transmission GO:0007270 1 0.021
positive regulation of rna metabolic process GO:0051254 59 0.020
regulation of response to external stimulus GO:0032101 31 0.020
Human Rat Worm Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
positive regulation of cell communication GO:0010647 56 0.020
single organism nuclear import GO:1902593 3 0.020
multicellular organism growth GO:0035264 4 0.020
positive regulation of synapse assembly GO:0051965 1 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.020
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.020
positive regulation of jak stat cascade GO:0046427 2 0.020
negative regulation of map kinase activity GO:0043407 2 0.020
regulation of erythrocyte differentiation GO:0045646 2 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.020
cellular component maintenance GO:0043954 3 0.020
negative regulation of programmed cell death GO:0043069 58 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
regulation of meiotic cell cycle GO:0051445 1 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
tube closure GO:0060606 1 0.019
forebrain development GO:0030900 96 0.019
Human Mouse
negative regulation of cell differentiation GO:0045596 46 0.019
autophagy GO:0006914 4 0.019
stem cell division GO:0017145 1 0.019
regulation of cell adhesion GO:0030155 15 0.019
Fly
positive regulation of cell morphogenesis involved in differentiation GO:0010770 6 0.019
Zebrafish
renal tubule morphogenesis GO:0061333 1 0.019
cardioblast migration GO:0003260 7 0.019
regulation of erk1 and erk2 cascade GO:0070372 4 0.019
cellular localization GO:0051641 97 0.019
cell matrix adhesion GO:0007160 4 0.019
neurological system process GO:0050877 62 0.019
protein complex localization GO:0031503 1 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
cell adhesion GO:0007155 40 0.019
Mouse Fly
establishment of protein localization to organelle GO:0072594 4 0.019
positive regulation of gene expression GO:0010628 71 0.019
sympathetic nervous system development GO:0048485 3 0.018
smad protein complex assembly GO:0007183 1 0.018
positive regulation of cell substrate adhesion GO:0010811 1 0.018
negative regulation of cellular component movement GO:0051271 18 0.018
Human Rat Worm
regulation of cytokine mediated signaling pathway GO:0001959 3 0.018
Human
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
positive regulation of catabolic process GO:0009896 4 0.018
ribonucleotide biosynthetic process GO:0009260 20 0.018
post embryonic organ development GO:0048569 4 0.018
cardiac conduction GO:0061337 3 0.018
myeloid cell differentiation GO:0030099 86 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
organic substance biosynthetic process GO:1901576 289 0.018
single organism reproductive process GO:0044702 40 0.018
Human Fly
regulation of metabolic process GO:0019222 359 0.018
Human Mouse
heart jogging GO:0003146 40 0.018
regulation of oocyte development GO:0060281 3 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
cytokinesis GO:0000910 3 0.017
synapse assembly GO:0007416 9 0.017
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.017
microtubule organizing center organization GO:0031023 1 0.017
neurotransmitter transport GO:0006836 2 0.017
forebrain regionalization GO:0021871 4 0.017
entrainment of circadian clock GO:0009649 2 0.017
positive regulation of signaling GO:0023056 56 0.017
erythrocyte differentiation GO:0030218 54 0.017
cranial ganglion development GO:0061550 3 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
synaptic transmission GO:0007268 35 0.017
Zebrafish
ion transport GO:0006811 114 0.017
immune system development GO:0002520 191 0.017
polarized epithelial cell differentiation GO:0030859 4 0.017
dendrite guidance GO:0070983 0 0.017
heart rudiment formation GO:0003315 5 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
Human
membrane invagination GO:0010324 1 0.017
negative regulation of chromosome organization GO:2001251 1 0.017
negative chemotaxis GO:0050919 1 0.017
Human Mouse Fly
axonogenesis GO:0007409 152 0.017
response to corticosteroid GO:0031960 1 0.017
Human
regulation of wound healing GO:0061041 2 0.017
myeloid cell development GO:0061515 32 0.017
circulatory system process GO:0003013 87 0.016
Human
fin development GO:0033333 77 0.016
glucose homeostasis GO:0042593 1 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
actin filament based process GO:0030029 64 0.016
Human
long chain fatty acid transport GO:0015909 1 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
exocrine pancreas development GO:0031017 28 0.016
collateral sprouting in absence of injury GO:0048669 4 0.016
negative regulation of catabolic process GO:0009895 3 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
heart looping GO:0001947 94 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
heart rudiment development GO:0003313 8 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
regulation of growth GO:0040008 42 0.015
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.015
cardioblast migration to the midline involved in heart rudiment formation GO:0003319 5 0.015
regulation of anatomical structure size GO:0090066 33 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
protein stabilization GO:0050821 2 0.015
organelle localization GO:0051640 49 0.015
cellular response to nutrient levels GO:0031669 2 0.015
nuclear migration GO:0007097 3 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
retina development in camera type eye GO:0060041 146 0.015
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.015
modulation by virus of host morphology or physiology GO:0019048 1 0.014
septum transversum development GO:0003343 4 0.014
protein deacetylation GO:0006476 3 0.014
negative regulation of gene expression GO:0010629 65 0.014
Mouse
female sex differentiation GO:0046660 4 0.014
Human
regulation of dendrite development GO:0050773 3 0.014
epithelial to mesenchymal transition GO:0001837 21 0.014
chemosensory behavior GO:0007635 1 0.014
positive regulation of catalytic activity GO:0043085 25 0.014
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.014
protein targeting to nucleus GO:0044744 3 0.014
positive regulation of cell differentiation GO:0045597 30 0.014
Zebrafish
positive regulation of jnk cascade GO:0046330 3 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
negative regulation of signaling GO:0023057 96 0.014
Human
protein complex subunit organization GO:0071822 46 0.014
Human
positive regulation of axonogenesis GO:0050772 6 0.014
Zebrafish
neuromuscular process controlling balance GO:0050885 3 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
Zebrafish
positive regulation of oocyte development GO:0060282 1 0.014

slit2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.086
disease of metabolism DOID:0014667 0 0.052
cardiovascular system disease DOID:1287 0 0.023
inherited metabolic disorder DOID:655 0 0.019