Danio rerio

86 known processes

smad9

MAD homolog 9 (Drosophila)

(Aliases: sma8,MGC103407,zgc:103407)

smad9 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
digestive system development GO:0055123 289 0.983
Zebrafish Fly
embryonic heart tube morphogenesis GO:0003143 108 0.924
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.922
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.912
Zebrafish Fly
digestive tract development GO:0048565 265 0.889
Zebrafish Fly
heart morphogenesis GO:0003007 156 0.887
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.855
Zebrafish
regulation of multicellular organismal development GO:2000026 223 0.832
Zebrafish Fly
convergent extension involved in gastrulation GO:0060027 71 0.815
Zebrafish
determination of left right symmetry GO:0007368 179 0.795
Zebrafish
convergent extension GO:0060026 118 0.792
Zebrafish
tube morphogenesis GO:0035239 349 0.765
Zebrafish Fly
determination of heart left right asymmetry GO:0061371 117 0.752
Zebrafish
heart looping GO:0001947 94 0.746
Zebrafish
positive regulation of cellular process GO:0048522 201 0.739
Zebrafish Worm Fly
heart development GO:0007507 313 0.736
Zebrafish
signal transduction GO:0007165 455 0.689
Zebrafish Mouse Fly
gastrulation GO:0007369 208 0.686
Zebrafish Fly
neuron differentiation GO:0030182 353 0.672
neuron development GO:0048666 262 0.657
specification of symmetry GO:0009799 204 0.636
Zebrafish
regulation of synapse organization GO:0050807 3 0.589
Fly
regulation of synapse assembly GO:0051963 3 0.582
Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.559
Zebrafish Mouse Fly
regulation of response to stimulus GO:0048583 269 0.523
Zebrafish
rna biosynthetic process GO:0032774 181 0.510
cell part morphogenesis GO:0032990 246 0.508
positive regulation of macromolecule metabolic process GO:0010604 93 0.493
Zebrafish Fly
skeletal system development GO:0001501 181 0.491
Mouse
cell migration involved in gastrulation GO:0042074 79 0.485
Zebrafish
ameboidal type cell migration GO:0001667 143 0.483
Zebrafish
cell projection organization GO:0030030 284 0.470
cell cycle GO:0007049 93 0.444
Worm Fly
regulation of macromolecule metabolic process GO:0060255 317 0.430
epithelial tube morphogenesis GO:0060562 148 0.429
Zebrafish Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.410
morphogenesis of an epithelium GO:0002009 333 0.405
Zebrafish Fly
response to lipid GO:0033993 60 0.400
embryonic limb morphogenesis GO:0030326 2 0.399
protein targeting to nucleus GO:0044744 3 0.398
establishment of spindle orientation GO:0051294 10 0.391
protein localization to nucleus GO:0034504 3 0.384
single organism organelle organization GO:1902589 199 0.375
positive regulation of biological process GO:0048518 253 0.373
Zebrafish Worm Fly
phosphorylation GO:0016310 69 0.370
Mouse
nuclear transport GO:0051169 4 0.367
negative regulation of cell cycle process GO:0010948 9 0.363
Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.362
sulfur compound metabolic process GO:0006790 13 0.358
regulation of blood circulation GO:1903522 32 0.348
heart jogging GO:0003146 40 0.339
Zebrafish
dorsal ventral pattern formation GO:0009953 125 0.337
regulation of developmental process GO:0050793 247 0.336
Zebrafish Worm Fly
cell motility GO:0048870 244 0.334
Zebrafish Fly
protein import into nucleus GO:0006606 3 0.325
chordate embryonic development GO:0043009 271 0.321
embryonic heart tube development GO:0035050 133 0.308
Zebrafish
regulation of signaling GO:0023051 235 0.306
Zebrafish
axon development GO:0061564 166 0.296
proteasomal protein catabolic process GO:0010498 2 0.295
cellular nitrogen compound metabolic process GO:0034641 290 0.294
nuclear import GO:0051170 3 0.279
nucleocytoplasmic transport GO:0006913 4 0.279
cell morphogenesis involved in differentiation GO:0000904 195 0.278
organonitrogen compound metabolic process GO:1901564 74 0.277
cellular amine metabolic process GO:0044106 2 0.272
positive regulation of map kinase activity GO:0043406 3 0.271
bmp signaling pathway involved in heart jogging GO:0003303 14 0.266
Zebrafish
single organism transport GO:0044765 206 0.263
phagocytosis GO:0006909 3 0.259
muscle structure development GO:0061061 196 0.259
organic substance biosynthetic process GO:1901576 289 0.257
amine metabolic process GO:0009308 2 0.251
positive regulation of metabolic process GO:0009893 108 0.251
Zebrafish Fly
single organism localization GO:1902578 225 0.247
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.242
positive regulation of cellular component biogenesis GO:0044089 3 0.242
Fly
heterocycle biosynthetic process GO:0018130 215 0.238
regulation of protein binding GO:0043393 3 0.236
single organismal cell cell adhesion GO:0016337 29 0.234
protein metabolic process GO:0019538 183 0.232
Mouse
regulation of cell differentiation GO:0045595 142 0.232
Zebrafish Fly
cell surface receptor signaling pathway GO:0007166 325 0.232
Zebrafish Mouse Fly
bmp signaling pathway involved in heart development GO:0061312 15 0.230
Zebrafish
neuron projection development GO:0031175 180 0.230
cytoskeleton organization GO:0007010 96 0.228
developmental growth involved in morphogenesis GO:0060560 86 0.226
establishment of mitotic spindle orientation GO:0000132 10 0.224
determination of dorsal ventral asymmetry GO:0048262 34 0.224
Zebrafish
regulation of protein import into nucleus GO:0042306 2 0.224
cellular component movement GO:0006928 335 0.219
Zebrafish Fly
protein import GO:0017038 3 0.218
organic cyclic compound metabolic process GO:1901360 301 0.214
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.213
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.213
cellular modified amino acid metabolic process GO:0006575 3 0.213
cellular component assembly GO:0022607 170 0.208
Fly
single organism nuclear import GO:1902593 3 0.207
nucleobase containing compound biosynthetic process GO:0034654 205 0.206
positive regulation of cellular metabolic process GO:0031325 94 0.204
Zebrafish Fly
positive regulation of protein metabolic process GO:0051247 23 0.203
regulation of mitotic cell cycle GO:0007346 25 0.201
Worm Fly
mitotic cell cycle GO:0000278 64 0.199
Worm Fly
dorsal convergence GO:0060030 14 0.193
Zebrafish
notochord development GO:0030903 54 0.191
regulation of embryonic development GO:0045995 47 0.188
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.188
oxoacid metabolic process GO:0043436 31 0.183
cellular amino acid metabolic process GO:0006520 7 0.180
regulation of cellular amine metabolic process GO:0033238 0 0.179
establishment of protein localization to organelle GO:0072594 4 0.178
muscle cell development GO:0055001 115 0.177
cellular macromolecule metabolic process GO:0044260 391 0.177
response to fluid shear stress GO:0034405 2 0.175
g1 s transition of mitotic cell cycle GO:0000082 1 0.172
Fly
fin regeneration GO:0031101 51 0.170
cellular aromatic compound metabolic process GO:0006725 295 0.170
striated muscle tissue development GO:0014706 110 0.170
regulation of axonogenesis GO:0050770 32 0.168
response to growth factor GO:0070848 39 0.168
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.166
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.166
Zebrafish Mouse Fly
single organism cell adhesion GO:0098602 29 0.162
cell morphogenesis GO:0000902 289 0.161
cellular protein catabolic process GO:0044257 4 0.161
axis elongation GO:0003401 31 0.160
regulation of cell migration GO:0030334 40 0.160
skeletal muscle tissue development GO:0007519 67 0.160
response to external stimulus GO:0009605 264 0.159
Fly
embryonic eye morphogenesis GO:0048048 30 0.158
organic cyclic compound biosynthetic process GO:1901362 223 0.157
regulation of cellular component organization GO:0051128 86 0.157
Fly
defense response GO:0006952 47 0.156
regulation of metabolic process GO:0019222 359 0.156
positive regulation of cell cycle GO:0045787 3 0.154
Worm
negative regulation of biological process GO:0048519 304 0.153
regulation of intracellular protein transport GO:0033157 3 0.153
aromatic compound biosynthetic process GO:0019438 217 0.147
positive regulation of nervous system development GO:0051962 25 0.146
Fly
generation of neurons GO:0048699 385 0.146
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.146
Zebrafish
regulation of cellular amino acid metabolic process GO:0006521 0 0.145
protein complex disassembly GO:0043241 1 0.145
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.145
organelle organization GO:0006996 227 0.143
response to nutrient GO:0007584 3 0.142
sensory organ development GO:0007423 393 0.142
Zebrafish Fly
blood circulation GO:0008015 87 0.139
regulation of cardiac muscle tissue development GO:0055024 1 0.138
chemotaxis GO:0006935 104 0.134
Fly
locomotion GO:0040011 313 0.134
Zebrafish Fly
sensory organ morphogenesis GO:0090596 200 0.133
Zebrafish Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.133
regulation of phosphorus metabolic process GO:0051174 43 0.131
gene expression GO:0010467 252 0.129
actin polymerization or depolymerization GO:0008154 2 0.129
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.129
cellular protein modification process GO:0006464 100 0.129
Mouse
regulation of signal transduction GO:0009966 225 0.128
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.128
positive regulation of catabolic process GO:0009896 4 0.127
regulation of locomotion GO:0040012 55 0.127
negative regulation of nuclear division GO:0051784 3 0.127
nuclear division GO:0000280 23 0.127
erk1 and erk2 cascade GO:0070371 4 0.126
protein modification process GO:0036211 100 0.123
Mouse
synapse organization GO:0050808 21 0.123
Fly
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.122
response to chemical GO:0042221 320 0.121
Mouse Fly
striated muscle cell development GO:0055002 108 0.119
stem cell differentiation GO:0048863 117 0.119
Fly
positive regulation of cellular protein metabolic process GO:0032270 22 0.118
axonogenesis GO:0007409 152 0.118
regulation of cell cycle GO:0051726 52 0.117
Worm Fly
regulation of dendrite development GO:0050773 3 0.116
regulation of rna biosynthetic process GO:2001141 213 0.116
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.116
embryonic cranial skeleton morphogenesis GO:0048701 90 0.116
cellular component morphogenesis GO:0032989 336 0.116
system process GO:0003008 185 0.115
transport GO:0006810 220 0.115
cellular macromolecule biosynthetic process GO:0034645 224 0.115
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.114
Zebrafish
regulation of neuron differentiation GO:0045664 56 0.114
negative chemotaxis GO:0050919 1 0.114
optic placode formation GO:0001743 4 0.114
embryonic skeletal system morphogenesis GO:0048704 93 0.113
response to stress GO:0006950 263 0.112
regulation of anatomical structure morphogenesis GO:0022603 130 0.111
Zebrafish
protein polymerization GO:0051258 4 0.111
protein complex biogenesis GO:0070271 30 0.110
regulation of cellular metabolic process GO:0031323 320 0.110
spindle localization GO:0051653 12 0.110
establishment of mitotic spindle localization GO:0040001 12 0.110
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.110
Zebrafish
regulation of cell motility GO:2000145 46 0.109
regulation of biological quality GO:0065008 263 0.108
Fly
tissue regeneration GO:0042246 74 0.107
blood vessel endothelial cell migration GO:0043534 18 0.106
nucleic acid templated transcription GO:0097659 181 0.106
regulation of multicellular organismal process GO:0051239 277 0.105
Zebrafish Worm Fly
notochord morphogenesis GO:0048570 17 0.105
cell migration involved in heart development GO:0060973 22 0.104
neural plate pattern specification GO:0060896 12 0.103
positive regulation of cellular amine metabolic process GO:0033240 0 0.103
morphogenesis of an epithelial fold GO:0060571 1 0.102
regulation of protein catabolic process GO:0042176 1 0.102
regulation of localization GO:0032879 104 0.100
regulation of axon extension GO:0030516 24 0.100
single organism cellular localization GO:1902580 46 0.098
mesenchyme development GO:0060485 127 0.097
microtubule based process GO:0007017 60 0.097
ventricular system development GO:0021591 12 0.096
cell death GO:0008219 121 0.096
organelle localization GO:0051640 49 0.096
regeneration GO:0031099 91 0.095
cell migration GO:0016477 237 0.095
Zebrafish Fly
positive regulation of oocyte development GO:0060282 1 0.095
Zebrafish
regulation of apoptotic process GO:0042981 98 0.094
regulation of biosynthetic process GO:0009889 250 0.092
negative regulation of mitotic cell cycle GO:0045930 11 0.092
Worm Fly
modification dependent protein catabolic process GO:0019941 3 0.091
gland development GO:0048732 143 0.091
positive regulation of striated muscle tissue development GO:0045844 1 0.090
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.088
cell projection morphogenesis GO:0048858 244 0.088
response to abiotic stimulus GO:0009628 122 0.088
response to organic substance GO:0010033 153 0.087
Mouse Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.086
Fly
regulation of binding GO:0051098 3 0.086
regulation of cytoplasmic transport GO:1903649 4 0.084
regulation of protein metabolic process GO:0051246 56 0.084
mesenchymal cell differentiation GO:0048762 87 0.084
single organism metabolic process GO:0044710 217 0.083
gall bladder development GO:0061010 1 0.083
phosphate containing compound metabolic process GO:0006796 108 0.083
Mouse
cytokinesis GO:0000910 3 0.082
negative regulation of cellular process GO:0048523 283 0.081
response to endogenous stimulus GO:0009719 83 0.081
Fly
stem cell maintenance GO:0019827 4 0.081
Fly
positive regulation of cell proliferation GO:0008284 15 0.080
mesenchymal cell proliferation GO:0010463 1 0.079
determination of ventral identity GO:0048264 21 0.079
Zebrafish
negative regulation of mitosis GO:0045839 3 0.078
cellular response to growth factor stimulus GO:0071363 39 0.077
Fly
camera type eye morphogenesis GO:0048593 108 0.077
nucleic acid metabolic process GO:0090304 244 0.077
protein phosphorylation GO:0006468 47 0.077
Mouse
regulation of neuron projection development GO:0010975 40 0.076
establishment of cell polarity GO:0030010 18 0.076
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.075
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.075
neuron projection extension GO:1990138 45 0.075
regulation of nervous system development GO:0051960 90 0.075
Fly
embryonic neurocranium morphogenesis GO:0048702 15 0.074
muscle tissue development GO:0060537 110 0.074
peptidyl serine modification GO:0018209 2 0.074
cellular component disassembly GO:0022411 1 0.073
embryonic organ development GO:0048568 381 0.073
Zebrafish
regulation of canonical wnt signaling pathway GO:0060828 34 0.073
microtubule cytoskeleton organization GO:0000226 33 0.072
positive regulation of gene expression GO:0010628 71 0.072
Zebrafish Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.071
regulation of heart contraction GO:0008016 32 0.071
negative regulation of protein localization to nucleus GO:1900181 2 0.071
regulation of chromosome segregation GO:0051983 1 0.071
transcription from rna polymerase ii promoter GO:0006366 80 0.071
Zebrafish Mouse Fly
regionalization GO:0003002 274 0.070
positive regulation of synapse assembly GO:0051965 1 0.070
Fly
striated muscle cell differentiation GO:0051146 129 0.069
skeletal system morphogenesis GO:0048705 102 0.069
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.069
brain development GO:0007420 293 0.069
Mouse
axon extension GO:0048675 45 0.069
cellular protein metabolic process GO:0044267 129 0.068
Mouse
regulation of cell projection organization GO:0031344 44 0.068
regulation of establishment of protein localization GO:0070201 4 0.068
endoderm development GO:0007492 49 0.067
Fly
cell division GO:0051301 20 0.067
Fly
convergent extension involved in axis elongation GO:0060028 26 0.067
phagocytosis engulfment GO:0006911 1 0.066
mesenchymal cell development GO:0014031 78 0.066
ear development GO:0043583 127 0.064
Zebrafish
regulation of anterior head development GO:2000742 2 0.064
stem cell division GO:0017145 1 0.063
Fly
eye morphogenesis GO:0048592 144 0.063
Fly
cortical actin cytoskeleton organization GO:0030866 1 0.063
actin filament polymerization GO:0030041 2 0.063
mapk cascade GO:0000165 18 0.063
regulation of protein targeting GO:1903533 2 0.062
neurological system process GO:0050877 62 0.062
epithelial cell migration GO:0010631 25 0.061
formation of primary germ layer GO:0001704 62 0.059
Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.059
regulation of erk1 and erk2 cascade GO:0070372 4 0.059
mitotic cell cycle process GO:1903047 48 0.059
Fly
spemann organizer formation GO:0060061 10 0.059
regulation of cellular protein metabolic process GO:0032268 52 0.058
transcription dna templated GO:0006351 181 0.058
regulation of neurogenesis GO:0050767 87 0.058
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.057
Zebrafish
pathway restricted smad protein phosphorylation GO:0060389 1 0.057
developmental cell growth GO:0048588 52 0.056
circulatory system process GO:0003013 87 0.056
regulation of phosphorylation GO:0042325 26 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.056
eye development GO:0001654 277 0.056
Fly
cell proliferation GO:0008283 80 0.055
stem cell development GO:0048864 82 0.055
Fly
chondrocyte development GO:0002063 4 0.055
positive regulation of muscle tissue development GO:1901863 1 0.055
regulation of cellular component movement GO:0051270 55 0.054
wnt signaling pathway GO:0016055 80 0.054
small molecule metabolic process GO:0044281 77 0.054
aging GO:0007568 2 0.054
regulation of protein transport GO:0051223 3 0.054
programmed cell death GO:0012501 119 0.053
negative regulation of intracellular protein transport GO:0090317 3 0.053
growth GO:0040007 174 0.052
Worm Fly
cell cycle g1 s phase transition GO:0044843 1 0.052
Fly
skeletal muscle organ development GO:0060538 78 0.052
protein complex assembly GO:0006461 30 0.052
cardiac muscle cell differentiation GO:0055007 30 0.051
regulation of cell development GO:0060284 100 0.051
Zebrafish
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.050
larval development GO:0002164 2 0.050
cellular response to chemical stimulus GO:0070887 157 0.050
Mouse Fly
phosphorus metabolic process GO:0006793 109 0.050
Mouse
camera type eye development GO:0043010 222 0.050
positive regulation of ras protein signal transduction GO:0046579 1 0.050
wound healing GO:0042060 90 0.049
regulation of kinase activity GO:0043549 15 0.049
cellular ketone metabolic process GO:0042180 11 0.049
establishment of spindle localization GO:0051293 12 0.048
single organism behavior GO:0044708 24 0.048
ubiquitin dependent protein catabolic process GO:0006511 3 0.048
cellular nitrogen compound biosynthetic process GO:0044271 218 0.048
regulation of phosphate metabolic process GO:0019220 43 0.048
tissue migration GO:0090130 37 0.048
positive regulation of transport GO:0051050 2 0.047
cell cycle process GO:0022402 53 0.047
Worm Fly
heterocycle metabolic process GO:0046483 290 0.047
mesoderm morphogenesis GO:0048332 51 0.046
negative regulation of signaling GO:0023057 96 0.046
cell substrate adhesion GO:0031589 4 0.046
protein localization GO:0008104 40 0.045
negative regulation of protein complex assembly GO:0031333 1 0.045
organelle assembly GO:0070925 110 0.045
cellular component biogenesis GO:0044085 178 0.045
Fly
immune system process GO:0002376 241 0.045
central nervous system neuron differentiation GO:0021953 74 0.045
lymph vessel development GO:0001945 27 0.045
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.044
macromolecule biosynthetic process GO:0009059 227 0.044
axon guidance GO:0007411 86 0.044
embryonic skeletal joint development GO:0072498 3 0.044
regulation of rna metabolic process GO:0051252 224 0.044
negative regulation of cell differentiation GO:0045596 46 0.043
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.043
Zebrafish Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.043
positive regulation of immune system process GO:0002684 17 0.043
positive regulation of cellular extravasation GO:0002693 1 0.043
regulation of cellular ketone metabolic process GO:0010565 7 0.042
nucleobase containing compound metabolic process GO:0006139 274 0.042
positive regulation of rna biosynthetic process GO:1902680 57 0.042
Zebrafish Fly
small gtpase mediated signal transduction GO:0007264 8 0.042
establishment of localization GO:0051234 244 0.042
macromolecule modification GO:0043412 111 0.042
Mouse
ossification GO:0001503 23 0.042
mitotic nuclear division GO:0007067 18 0.042
positive regulation of muscle organ development GO:0048636 1 0.042
hindbrain development GO:0030902 91 0.041
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.041
thrombocyte differentiation GO:0002574 4 0.040
positive regulation of developmental process GO:0051094 50 0.040
Zebrafish Worm Fly
positive regulation of phosphate metabolic process GO:0045937 21 0.040
actomyosin structure organization GO:0031032 53 0.040
positive regulation of signaling GO:0023056 56 0.040
maintenance of location GO:0051235 4 0.039
germ line stem cell division GO:0042078 1 0.039
Fly
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.039
cell growth GO:0016049 57 0.039
regulation of meiotic cell cycle GO:0051445 1 0.039
Worm
neural tube patterning GO:0021532 33 0.038
embryonic heart tube left right pattern formation GO:0060971 5 0.038
regulation of protein localization to nucleus GO:1900180 2 0.038
cartilage development GO:0051216 96 0.038
Mouse
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.037
positive regulation of signal transduction GO:0009967 56 0.037
response to external biotic stimulus GO:0043207 97 0.037
response to wounding GO:0009611 116 0.037
epithelium migration GO:0090132 25 0.037
post anal tail morphogenesis GO:0036342 19 0.037
Zebrafish
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.037
endothelial cell migration GO:0043542 19 0.037
regulation of cell size GO:0008361 29 0.037
axis specification GO:0009798 43 0.037
myeloid cell development GO:0061515 32 0.036
activation of mapk activity GO:0000187 3 0.036
response to radiation GO:0009314 51 0.036
stem cell proliferation GO:0072089 4 0.036
regulation of nucleocytoplasmic transport GO:0046822 2 0.036
fin development GO:0033333 77 0.036
regulation of cellular response to growth factor stimulus GO:0090287 35 0.036
gland morphogenesis GO:0022612 13 0.035
muscle organ development GO:0007517 101 0.035
synaptic growth at neuromuscular junction GO:0051124 2 0.035
Fly
positive regulation of wound healing GO:0090303 1 0.035
liver development GO:0001889 96 0.035
heart field specification GO:0003128 1 0.035
atrial ventricular junction remodeling GO:0003294 2 0.035
regulation of bmp signaling pathway GO:0030510 39 0.034
Zebrafish
cell adhesion GO:0007155 40 0.034
regulation of muscle organ development GO:0048634 9 0.034
angiogenesis GO:0001525 158 0.034
mesoderm formation GO:0001707 43 0.034
immune system development GO:0002520 191 0.034
regulation of nucleoside metabolic process GO:0009118 2 0.034
cardiac muscle tissue development GO:0048738 48 0.034
cellular response to stress GO:0033554 62 0.034
regulation of organ morphogenesis GO:2000027 35 0.034
Zebrafish
regulation of cardiac muscle cell differentiation GO:2000725 1 0.033
regulation of sequestering of calcium ion GO:0051282 4 0.033
regulation of molecular function GO:0065009 70 0.033
positive regulation of nucleic acid templated transcription GO:1903508 57 0.033
Zebrafish Fly
lymph vessel morphogenesis GO:0036303 25 0.033
positive regulation of cellular component organization GO:0051130 13 0.033
Fly
organic acid metabolic process GO:0006082 31 0.032
cell cell signaling involved in cell fate commitment GO:0045168 12 0.032
regulation of biomineral tissue development GO:0070167 2 0.032
regulation of developmental growth GO:0048638 38 0.032
Worm Fly
biosynthetic process GO:0009058 294 0.032
cellular protein complex assembly GO:0043623 19 0.032
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.032
hepatocyte proliferation GO:0072574 2 0.032
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.032
Fly
muscle cell differentiation GO:0042692 139 0.032
positive regulation of biosynthetic process GO:0009891 68 0.032
Zebrafish Fly
protein complex subunit organization GO:0071822 46 0.031
membrane invagination GO:0010324 1 0.031
regulation of cell activation GO:0050865 1 0.031
neural crest cell development GO:0014032 62 0.031
positive regulation of response to stimulus GO:0048584 80 0.030
regulation of growth GO:0040008 42 0.030
Worm Fly
heart contraction GO:0060047 71 0.030
embryonic camera type eye morphogenesis GO:0048596 19 0.030
response to fibroblast growth factor GO:0071774 22 0.030
biological adhesion GO:0022610 40 0.030
positive regulation of dna metabolic process GO:0051054 1 0.029
regulation of epithelial to mesenchymal transition GO:0010717 3 0.029
neural tube development GO:0021915 62 0.029
regulation of protein ubiquitination GO:0031396 3 0.029
regulation of establishment of planar polarity GO:0090175 4 0.029
apical junction assembly GO:0043297 1 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.028
Zebrafish Fly
peptidyl serine phosphorylation GO:0018105 1 0.028
regulation of gastrulation GO:0010470 24 0.028
death GO:0016265 121 0.028
cellular component assembly involved in morphogenesis GO:0010927 107 0.028
exocytosis GO:0006887 1 0.028
blood vessel development GO:0001568 246 0.028
Zebrafish
regulation of endocytosis GO:0030100 7 0.028
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.028
cellular protein localization GO:0034613 20 0.027
eye photoreceptor cell differentiation GO:0001754 45 0.027
macromolecule localization GO:0033036 54 0.027
cell matrix adhesion GO:0007160 4 0.027
embryonic camera type eye development GO:0031076 29 0.026
regulation of cellular protein catabolic process GO:1903362 1 0.026
cellular response to endogenous stimulus GO:0071495 68 0.026
Fly
taxis GO:0042330 109 0.026
Fly
positive regulation of cell adhesion GO:0045785 1 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
macromolecular complex subunit organization GO:0043933 74 0.026
regulation of cell death GO:0010941 103 0.026
regulation of extent of cell growth GO:0061387 29 0.026
positive regulation of cell activation GO:0050867 1 0.026
cellular response to biotic stimulus GO:0071216 3 0.026
regulation of smoothened signaling pathway GO:0008589 18 0.026
protein depolymerization GO:0051261 1 0.026
anterior posterior axon guidance GO:0033564 5 0.025
somatic muscle development GO:0007525 4 0.025
response to hypoxia GO:0001666 25 0.025
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.025
regulation of protein modification process GO:0031399 29 0.025
neural plate anterior posterior regionalization GO:0021999 8 0.025
photoreceptor cell differentiation GO:0046530 55 0.025
specification of axis polarity GO:0065001 4 0.024
behavior GO:0007610 74 0.024
negative regulation of synapse assembly GO:0051964 2 0.024
hepaticobiliary system development GO:0061008 98 0.024
spinal cord development GO:0021510 46 0.024
regulation of protein phosphorylation GO:0001932 18 0.024
morphogenesis of a branching epithelium GO:0061138 16 0.024
regulation of mitosis GO:0007088 9 0.023

smad9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024