Danio rerio

0 known processes

smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

(Aliases: zgc:66238,wu:fa56c07,wu:fi27f11,psa-4)

smarca2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.211
Human Fly
rna metabolic process GO:0016070 219 0.146
Human Fly
organelle organization GO:0006996 227 0.144
Fly
aromatic compound biosynthetic process GO:0019438 217 0.136
Human Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.131
Human Fly
positive regulation of transport GO:0051050 2 0.131
rna biosynthetic process GO:0032774 181 0.128
Human Fly
heterocycle biosynthetic process GO:0018130 215 0.107
Human Fly
establishment of protein localization to organelle GO:0072594 4 0.102
regulation of macromolecule metabolic process GO:0060255 317 0.095
Human Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.095
neuron neuron synaptic transmission GO:0007270 1 0.088
cellular macromolecule metabolic process GO:0044260 391 0.086
Human Fly
negative regulation of protein phosphorylation GO:0001933 4 0.085
organic acid metabolic process GO:0006082 31 0.084
cellular amino acid metabolic process GO:0006520 7 0.083
negative regulation of macromolecule metabolic process GO:0010605 76 0.083
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.076
organic cyclic compound biosynthetic process GO:1901362 223 0.074
Human Fly
cellular ketone metabolic process GO:0042180 11 0.074
regulation of transcription dna templated GO:0006355 213 0.073
Human Fly
regulation of cellular amine metabolic process GO:0033238 0 0.073
regulation of cellular biosynthetic process GO:0031326 245 0.072
Human Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.071
Human Fly
nucleic acid metabolic process GO:0090304 244 0.071
Human Fly
aging GO:0007568 2 0.069
cellular protein modification process GO:0006464 100 0.068
Fly
nucleic acid templated transcription GO:0097659 181 0.066
Human Fly
regulation of rna metabolic process GO:0051252 224 0.063
Human Fly
maintenance of location GO:0051235 4 0.062
adherens junction organization GO:0034332 4 0.061
cellular amine metabolic process GO:0044106 2 0.061
regulation of multicellular organismal development GO:2000026 223 0.060
Fly
regulation of establishment of protein localization GO:0070201 4 0.060
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.058
regulation of gene expression GO:0010468 265 0.054
Human Fly
regulation of biosynthetic process GO:0009889 250 0.053
Human Fly
amine metabolic process GO:0009308 2 0.053
peptidyl threonine phosphorylation GO:0018107 1 0.052
regulation of nitrogen compound metabolic process GO:0051171 251 0.052
Human Fly
regulation of cellular metabolic process GO:0031323 320 0.052
Human Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.052
Human Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.051
regulation of primary metabolic process GO:0080090 311 0.051
Human Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.050
Human Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.046
Human Fly
neuron differentiation GO:0030182 353 0.046
Fly
regulation of metabolic process GO:0019222 359 0.045
Human Fly
macromolecule modification GO:0043412 111 0.045
Fly
modification dependent protein catabolic process GO:0019941 3 0.045
transcription from rna polymerase ii promoter GO:0006366 80 0.045
Human
cellular biosynthetic process GO:0044249 286 0.043
Human Fly
gene expression GO:0010467 252 0.043
Human Fly
nitrogen compound metabolic process GO:0006807 319 0.043
Human Fly
larval development GO:0002164 2 0.042
carboxylic acid metabolic process GO:0019752 22 0.040
macromolecule biosynthetic process GO:0009059 227 0.040
Human Fly
oxoacid metabolic process GO:0043436 31 0.039
negative regulation of cellular metabolic process GO:0031324 77 0.039
Human
positive regulation of cell cycle GO:0045787 3 0.039
cellular protein metabolic process GO:0044267 129 0.038
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.038
Human
brain development GO:0007420 293 0.037
germ line stem cell maintenance GO:0030718 2 0.037
adult behavior GO:0030534 2 0.036
regulation of reproductive process GO:2000241 4 0.036
regulation of oocyte development GO:0060281 3 0.036
regulation of protein transport GO:0051223 3 0.036
regulation of rna biosynthetic process GO:2001141 213 0.035
Human Fly
nucleobase containing compound metabolic process GO:0006139 274 0.035
Human Fly
cellular carbohydrate metabolic process GO:0044262 4 0.035
phagocytosis GO:0006909 3 0.035
Fly
growth GO:0040007 174 0.034
Human
regulation of autophagy GO:0010506 3 0.034
primitive erythrocyte differentiation GO:0060319 5 0.034
organic substance biosynthetic process GO:1901576 289 0.034
Human Fly
cellular component assembly GO:0022607 170 0.034
regulation of multicellular organism growth GO:0040014 4 0.033
central nervous system development GO:0007417 387 0.033
immune system process GO:0002376 241 0.033
small molecule metabolic process GO:0044281 77 0.033
single organism localization GO:1902578 225 0.032
Fly
regulation of binding GO:0051098 3 0.031
phosphorylation GO:0016310 69 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
Human Fly
regulation of receptor activity GO:0010469 2 0.030
regulation of wound healing GO:0061041 2 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.029
lipid storage GO:0019915 1 0.029
energy reserve metabolic process GO:0006112 2 0.029
regulation of erk1 and erk2 cascade GO:0070372 4 0.028
protein metabolic process GO:0019538 183 0.028
Fly
macromolecular complex subunit organization GO:0043933 74 0.028
Fly
response to alkaloid GO:0043279 2 0.028
response to stress GO:0006950 263 0.028
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
regulation of cytokine production GO:0001817 3 0.028
negative regulation of biological process GO:0048519 304 0.027
Human Mouse Fly
cellular component biogenesis GO:0044085 178 0.027
erk1 and erk2 cascade GO:0070371 4 0.027
negative regulation of cytokine production GO:0001818 1 0.026
reactive oxygen species metabolic process GO:0072593 6 0.026
response to hexose GO:0009746 3 0.026
regulation of dna replication GO:0006275 3 0.026
meiotic nuclear division GO:0007126 4 0.026
nuclear migration GO:0007097 3 0.026
response to chemical GO:0042221 320 0.026
Fly
response to glucose GO:0009749 3 0.026
protein modification process GO:0036211 100 0.026
Fly
mononuclear cell proliferation GO:0032943 1 0.025
negative regulation of protein kinase activity GO:0006469 4 0.025
transcription dna templated GO:0006351 181 0.025
Human Fly
response to monosaccharide GO:0034284 3 0.025
gastrulation GO:0007369 208 0.025
regulation of glucose import GO:0046324 1 0.024
multicellular organism growth GO:0035264 4 0.024
single organism membrane fusion GO:0044801 2 0.024
establishment of localization GO:0051234 244 0.024
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
regulation of carbohydrate metabolic process GO:0006109 4 0.024
cellular protein catabolic process GO:0044257 4 0.024
negative regulation of kinase activity GO:0033673 4 0.024
modification dependent macromolecule catabolic process GO:0043632 3 0.024
leukocyte proliferation GO:0070661 1 0.023
cellular amide metabolic process GO:0043603 4 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
regulation of stem cell proliferation GO:0072091 2 0.022
Fly
organonitrogen compound metabolic process GO:1901564 74 0.022
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.022
cell migration GO:0016477 237 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
lymphocyte proliferation GO:0046651 1 0.022
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.022
programmed cell death GO:0012501 119 0.022
peptidyl serine modification GO:0018209 2 0.021
actin filament based process GO:0030029 64 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.021
Human
rna localization GO:0006403 4 0.021
nuclear transport GO:0051169 4 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
positive regulation of cell activation GO:0050867 1 0.021
regulation of blood vessel size GO:0050880 2 0.021
negative regulation of signaling GO:0023057 96 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
cytokinesis GO:0000910 3 0.020
stem cell proliferation GO:0072089 4 0.020
Fly
phosphate containing compound metabolic process GO:0006796 108 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
negative regulation of cellular process GO:0048523 283 0.020
Human Mouse Fly
regulation of cell activation GO:0050865 1 0.020
blood vessel morphogenesis GO:0048514 216 0.020
tube morphogenesis GO:0035239 349 0.020
regulation of reactive oxygen species metabolic process GO:2000377 2 0.020
cellular component morphogenesis GO:0032989 336 0.020
Fly
cell proliferation GO:0008283 80 0.020
Mouse Fly
system process GO:0003008 185 0.019
single organism organelle organization GO:1902589 199 0.019
Fly
leukocyte homeostasis GO:0001776 2 0.019
protein localization GO:0008104 40 0.019
actin cytoskeleton organization GO:0030036 63 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
Fly
morphogenesis of an epithelium GO:0002009 333 0.019
meiotic cell cycle process GO:1903046 3 0.019
protein targeting to nucleus GO:0044744 3 0.019
organelle assembly GO:0070925 110 0.019
nuclear export GO:0051168 1 0.018
regulation of metal ion transport GO:0010959 4 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
cell matrix adhesion GO:0007160 4 0.018
regulation of biological quality GO:0065008 263 0.018
negative regulation of signal transduction GO:0009968 94 0.018
blood vessel development GO:0001568 246 0.018
positive regulation of nucleic acid templated transcription GO:1903508 57 0.018
Human Fly
organic cyclic compound metabolic process GO:1901360 301 0.018
Human Fly
protein localization to nucleus GO:0034504 3 0.018
cognition GO:0050890 1 0.018
peptidyl threonine modification GO:0018210 1 0.018
regulation of protein complex assembly GO:0043254 3 0.018
regulation of protein phosphorylation GO:0001932 18 0.018
response to drug GO:0042493 3 0.018
regulation of cellular protein metabolic process GO:0032268 52 0.018
cellular response to chemical stimulus GO:0070887 157 0.017
smoothened signaling pathway GO:0007224 30 0.017
organic acid catabolic process GO:0016054 3 0.017
membrane fusion GO:0061025 2 0.017
single organism nuclear import GO:1902593 3 0.017
cell motility GO:0048870 244 0.017
regulation of transporter activity GO:0032409 2 0.017
meiotic chromosome segregation GO:0045132 3 0.017
digestive system development GO:0055123 289 0.017
positive regulation of glucose import GO:0046326 1 0.017
negative regulation of metabolic process GO:0009892 86 0.017
Human
erythrocyte differentiation GO:0030218 54 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
protein stabilization GO:0050821 2 0.017
protein import GO:0017038 3 0.016
regulation of cellular component organization GO:0051128 86 0.016
Human
macromolecular complex assembly GO:0065003 35 0.016
regulation of receptor mediated endocytosis GO:0048259 4 0.016
gtp metabolic process GO:0046039 4 0.016
protein targeting to membrane GO:0006612 1 0.016
response to carbohydrate GO:0009743 3 0.016
negative regulation of ras protein signal transduction GO:0046580 1 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
Worm
peptidyl serine phosphorylation GO:0018105 1 0.016
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.016
determination of left right symmetry GO:0007368 179 0.016
regulation of protein metabolic process GO:0051246 56 0.016
regulation of cell development GO:0060284 100 0.016
Fly
regulation of leukocyte mediated immunity GO:0002703 1 0.016
regulation of synapse organization GO:0050807 3 0.016
regulation of mrna processing GO:0050684 3 0.016
nitric oxide metabolic process GO:0046209 2 0.016
positive regulation of protein kinase b signaling GO:0051897 1 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
Human Fly
positive regulation of secretion GO:0051047 1 0.016
vacuolar transport GO:0007034 2 0.016
cortical cytoskeleton organization GO:0030865 1 0.015
regulation of protein binding GO:0043393 3 0.015
protein polymerization GO:0051258 4 0.015
glycerophospholipid biosynthetic process GO:0046474 1 0.015
apoptotic process GO:0006915 116 0.015
negative regulation of immune response GO:0050777 2 0.015
biosynthetic process GO:0009058 294 0.015
Human Fly
negative regulation of gene expression GO:0010629 65 0.015
Human
proteasomal protein catabolic process GO:0010498 2 0.015
maternal determination of anterior posterior axis embryo GO:0008358 4 0.015
protein secretion GO:0009306 1 0.015
positive regulation of biological process GO:0048518 253 0.015
Human Fly
negative regulation of catabolic process GO:0009895 3 0.015
oocyte anterior posterior axis specification GO:0007314 4 0.015
regulation of hormone secretion GO:0046883 2 0.015
regulation of organelle organization GO:0033043 29 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
cell junction maintenance GO:0034331 2 0.015
positive regulation of cell division GO:0051781 2 0.015
autophagy GO:0006914 4 0.015
response to biotic stimulus GO:0009607 97 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
negative regulation of cell communication GO:0010648 96 0.015
protein phosphorylation GO:0006468 47 0.015
intracellular mrna localization GO:0008298 1 0.015
centrosome organization GO:0051297 1 0.015
toll like receptor signaling pathway GO:0002224 4 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
adherens junction maintenance GO:0034334 2 0.015
cellular component maintenance GO:0043954 3 0.014
response to nutrient GO:0007584 3 0.014
regulation of dna templated transcription in response to stress GO:0043620 0 0.014
cell morphogenesis GO:0000902 289 0.014
Fly
regulation of cell maturation GO:1903429 1 0.014
macromolecule localization GO:0033036 54 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
Human Fly
positive regulation of rna metabolic process GO:0051254 59 0.014
Human Fly
macromolecular complex disassembly GO:0032984 1 0.014
actin filament polymerization GO:0030041 2 0.014
regulation of glucose transport GO:0010827 1 0.014
death GO:0016265 121 0.014
immunoglobulin mediated immune response GO:0016064 3 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
Human Fly
regulation of synapse assembly GO:0051963 3 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.014
localization of cell GO:0051674 244 0.014
stem cell division GO:0017145 1 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
Fly
regulation of leukocyte mediated cytotoxicity GO:0001910 1 0.013
hemopoiesis GO:0030097 183 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
g protein coupled receptor signaling pathway GO:0007186 74 0.013
cell projection organization GO:0030030 284 0.013
Fly
stem cell maintenance GO:0019827 4 0.013
protein import into nucleus GO:0006606 3 0.013
lipid metabolic process GO:0006629 52 0.013
cellular response to organic substance GO:0071310 105 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
cellular component disassembly GO:0022411 1 0.013
positive regulation of biosynthetic process GO:0009891 68 0.013
Human Fly
positive regulation of cytoskeleton organization GO:0051495 3 0.013
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
Human Fly
rna 3 end processing GO:0031123 2 0.013
receptor internalization GO:0031623 2 0.013
medulla oblongata development GO:0021550 4 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
glucose import GO:0046323 2 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
positive regulation of secretion by cell GO:1903532 1 0.012
cell substrate adhesion GO:0031589 4 0.012
mrna 3 end processing GO:0031124 2 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
single organism membrane organization GO:0044802 20 0.012
regulation of protein targeting GO:1903533 2 0.012
regulation of calcium ion transport GO:0051924 2 0.012
erythrocyte homeostasis GO:0034101 55 0.012
organophosphate biosynthetic process GO:0090407 23 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
neuron projection morphogenesis GO:0048812 161 0.012
Fly
cell cycle process GO:0022402 53 0.012
Fly
positive regulation of gene expression GO:0010628 71 0.012
Human Fly
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.012
b cell mediated immunity GO:0019724 3 0.012
heterocycle metabolic process GO:0046483 290 0.012
Human Fly
muscle structure development GO:0061061 196 0.012
Mouse Fly
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
response to wounding GO:0009611 116 0.012
phosphorus metabolic process GO:0006793 109 0.012
superoxide metabolic process GO:0006801 2 0.012
regulation of growth rate GO:0040009 1 0.012
lipid biosynthetic process GO:0008610 22 0.012
cell killing GO:0001906 2 0.012
myeloid cell homeostasis GO:0002262 56 0.011
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.011
regulation of protein polymerization GO:0032271 2 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
single organism metabolic process GO:0044710 217 0.011
Fly
microtubule organizing center organization GO:0031023 1 0.011
homeostatic process GO:0042592 142 0.011
wound healing GO:0042060 90 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
Human
establishment of endothelial barrier GO:0061028 3 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.011
regulation of dendrite development GO:0050773 3 0.011
organelle fusion GO:0048284 3 0.011
glycerolipid biosynthetic process GO:0045017 1 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
covalent chromatin modification GO:0016569 20 0.011
Fly
cellular response to starvation GO:0009267 1 0.011
monoamine transport GO:0015844 1 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
Fly
protein homooligomerization GO:0051260 3 0.011
microtubule based process GO:0007017 60 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
regulation of natural killer cell mediated cytotoxicity GO:0042269 1 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
regulation of vasculature development GO:1901342 33 0.011
b cell activation GO:0042113 2 0.010
convergent extension GO:0060026 118 0.010
primary neural tube formation GO:0014020 1 0.010
regulation of inflammatory response GO:0050727 2 0.010
regulation of lymphocyte mediated immunity GO:0002706 1 0.010
cellular response to external stimulus GO:0071496 2 0.010
cell death GO:0008219 121 0.010
positive regulation of cell differentiation GO:0045597 30 0.010
positive regulation of muscle cell differentiation GO:0051149 1 0.010
regulation of cell cycle GO:0051726 52 0.010
Fly
cellular transition metal ion homeostasis GO:0046916 3 0.010
positive regulation of metabolic process GO:0009893 108 0.010
Human Fly
gland development GO:0048732 143 0.010
regulation of establishment of planar polarity GO:0090175 4 0.010
multicellular organismal metabolic process GO:0044236 2 0.010
positive regulation of catabolic process GO:0009896 4 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
small molecule catabolic process GO:0044282 3 0.010
ras protein signal transduction GO:0007265 7 0.010
cell surface receptor signaling pathway GO:0007166 325 0.010
Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.010
Human
chromosome organization GO:0051276 31 0.010
Fly
endosomal transport GO:0016197 2 0.010

smarca2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
disease of metabolism DOID:0014667 0 0.018
nervous system disease DOID:863 0 0.012
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012
musculoskeletal system disease DOID:17 0 0.012
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011
inherited metabolic disorder DOID:655 0 0.011