|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.739
|
Human Fly |
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.635
|
Human Fly |
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.601
|
Human Fly |
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.576
|
Human Fly |
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.544
|
Human Fly |
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.513
|
Human Fly |
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.501
|
Human Fly |
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.499
|
Human Fly |
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.495
|
Human Fly |
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.457
|
Human Fly |
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.457
|
Human Fly |
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.436
|
Human Fly |
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.417
|
Human Fly |
|
|
gene expression
|
GO:0010467 |
252 |
0.408
|
Human Fly |
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.389
|
Human Fly |
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.387
|
Human Fly |
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.374
|
Human Fly |
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.359
|
Human Fly |
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.355
|
Worm |
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.353
|
Human Fly |
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.349
|
Human Fly |
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.326
|
Human Fly |
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.323
|
Human Worm Fly |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.321
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.319
|
Human Fly |
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.319
|
Human Fly |
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.316
|
Human Fly |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.304
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.298
|
Human Fly |
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.284
|
Human Fly |
|
|
signal transduction
|
GO:0007165 |
455 |
0.268
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.266
|
Human Fly |
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.254
|
Human Fly |
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.245
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.240
|
Human Fly |
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.236
|
Human Fly |
|
|
cellular component movement
|
GO:0006928 |
335 |
0.234
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.231
|
Human Fly |
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.226
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.215
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.214
|
Human Fly |
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.214
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.204
|
Human Fly |
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.199
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.196
|
Human Fly |
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.192
|
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.191
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.189
|
Human Fly |
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.185
|
Human Fly |
|
|
growth
|
GO:0040007 |
174 |
0.183
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.171
|
Worm |
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
57 |
0.164
|
Human Fly |
|
|
gastrulation
|
GO:0007369 |
208 |
0.164
|
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.154
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.150
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.149
|
Fly |
|
|
chromosome organization
|
GO:0051276 |
31 |
0.148
|
Human Fly |
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.139
|
Human Fly |
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.137
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.133
|
Human Fly |
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.130
|
Human Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.130
|
Fly |
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.119
|
Human Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.118
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
2 |
0.117
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.110
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.108
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.107
|
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.105
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
2 |
0.105
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.103
|
Fly |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
4 |
0.102
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.102
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.100
|
Human Fly |
|
|
phagocytosis
|
GO:0006909 |
3 |
0.100
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
104 |
0.099
|
|
|
|
convergent extension
|
GO:0060026 |
118 |
0.096
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.096
|
|
|
|
aging
|
GO:0007568 |
2 |
0.094
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.088
|
|
|
|
methylation
|
GO:0032259 |
22 |
0.087
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.085
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.085
|
|
|
|
regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034243 |
3 |
0.082
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.081
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.080
|
Worm Fly |
|
|
regulation of protein complex assembly
|
GO:0043254 |
3 |
0.080
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.078
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.077
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.077
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.077
|
Fly |
|
|
response to stress
|
GO:0006950 |
263 |
0.074
|
|
|
|
transcription from rna polymerase iii promoter
|
GO:0006383 |
1 |
0.074
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.073
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
59 |
0.072
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.072
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.071
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.071
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.070
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.069
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.069
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.068
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.068
|
Human Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
2 |
0.067
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.067
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.066
|
|
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.064
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.064
|
|
|
|
muscle structure development
|
GO:0061061 |
196 |
0.063
|
Zebrafish Fly |
|
|
homeostatic process
|
GO:0042592 |
142 |
0.062
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.060
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.060
|
|
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.060
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.059
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.059
|
Worm |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.059
|
Worm |
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.058
|
Fly |
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.058
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.057
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
97 |
0.057
|
|
|
|
response to organic substance
|
GO:0010033 |
153 |
0.057
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.057
|
Human Fly |
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.056
|
Human |
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.055
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.055
|
Worm |
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.055
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.054
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.053
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.053
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
57 |
0.051
|
Human Fly |
|
|
protein methylation
|
GO:0006479 |
13 |
0.051
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.051
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
55 |
0.050
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.050
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.050
|
Human Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.050
|
|
|
|
dna metabolic process
|
GO:0006259 |
27 |
0.050
|
Fly |
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.048
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.048
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
1 |
0.048
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
59 |
0.048
|
Human Fly |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
30 |
0.048
|
|
|
|
transport
|
GO:0006810 |
220 |
0.047
|
Worm |
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.047
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.046
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
11 |
0.046
|
Human |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.046
|
Human Fly |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.046
|
Human Fly |
|
|
neuron development
|
GO:0048666 |
262 |
0.046
|
Worm Fly |
|
|
digestive system development
|
GO:0055123 |
289 |
0.046
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.046
|
Zebrafish |
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.045
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.045
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.045
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.045
|
Worm Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.045
|
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.044
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.044
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.044
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.044
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
80 |
0.044
|
|
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.043
|
Zebrafish |
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.043
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.043
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.043
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
2 |
0.043
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.043
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
45 |
0.042
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.042
|
Worm |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.042
|
Human Fly |
|
|
protein acetylation
|
GO:0006473 |
2 |
0.041
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.041
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.041
|
Worm Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.040
|
Zebrafish |
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
4 |
0.040
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
2 |
0.040
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.039
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
86 |
0.039
|
|
|
|
organelle assembly
|
GO:0070925 |
110 |
0.039
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.039
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.038
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
71 |
0.038
|
|
|
|
muscle organ development
|
GO:0007517 |
101 |
0.038
|
Fly |
|
|
regulation of cell shape
|
GO:0008360 |
1 |
0.038
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
57 |
0.038
|
Human Fly |
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.038
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.037
|
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.037
|
|
|
|
regulation of histone methylation
|
GO:0031060 |
3 |
0.037
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.037
|
Zebrafish |
|
|
chromatin organization
|
GO:0006325 |
22 |
0.037
|
Human Fly |
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.037
|
|
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.036
|
Fly |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.036
|
Worm |
|
|
regulation of mrna splicing via spliceosome
|
GO:0048024 |
3 |
0.036
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
3 |
0.036
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.036
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
2 |
0.035
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.035
|
|
|
|
cell death
|
GO:0008219 |
121 |
0.035
|
Worm |
|
|
system process
|
GO:0003008 |
185 |
0.034
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
48 |
0.034
|
|
|
|
dna modification
|
GO:0006304 |
8 |
0.034
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
90 |
0.034
|
|
|
|
cognition
|
GO:0050890 |
1 |
0.033
|
|
|
|
regulation of binding
|
GO:0051098 |
3 |
0.033
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.033
|
|
|
|
macromolecule methylation
|
GO:0043414 |
19 |
0.033
|
|
|
|
larval development
|
GO:0002164 |
2 |
0.033
|
Worm |
|
|
apoptotic process
|
GO:0006915 |
116 |
0.033
|
Worm |
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.033
|
Fly |
|
|
histone lysine methylation
|
GO:0034968 |
12 |
0.032
|
|
|
|
chromatin modification
|
GO:0016568 |
21 |
0.032
|
Human Fly |
|
|
regulation of growth
|
GO:0040008 |
42 |
0.032
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
2 |
0.032
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
116 |
0.032
|
|
|
|
dna templated transcription initiation
|
GO:0006352 |
1 |
0.032
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.032
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.032
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.032
|
|
|
|
exocytosis
|
GO:0006887 |
1 |
0.032
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.031
|
|
|
|
dna templated transcription elongation
|
GO:0006354 |
3 |
0.031
|
|
|
|
camera type eye development
|
GO:0043010 |
222 |
0.031
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
2 |
0.031
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
22 |
0.031
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.031
|
|
|
|
cell cycle arrest
|
GO:0007050 |
1 |
0.031
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.031
|
Worm |
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
22 |
0.031
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
3 |
0.030
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.030
|
|
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.030
|
|
|
|
immune system development
|
GO:0002520 |
191 |
0.030
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.030
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.030
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.030
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.029
|
Human Fly |
|
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.029
|
|
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.029
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.029
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
54 |
0.029
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.029
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.029
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
8 |
0.029
|
|
|
|
single organism localization
|
GO:1902578 |
225 |
0.029
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.029
|
Worm |
|
|
regulation of synapse organization
|
GO:0050807 |
3 |
0.028
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
3 |
0.028
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
102 |
0.028
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.028
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.028
|
|
|
|
response to other organism
|
GO:0051707 |
97 |
0.027
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.027
|
|
|
|
fin regeneration
|
GO:0031101 |
51 |
0.027
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
3 |
0.027
|
|
|
|
response to uv
|
GO:0009411 |
3 |
0.027
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.027
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
59 |
0.027
|
Human Fly |
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.027
|
|
|
|
adult behavior
|
GO:0030534 |
2 |
0.026
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
97 |
0.026
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.026
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
45 |
0.026
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.026
|
|
|
|
response to light stimulus
|
GO:0009416 |
46 |
0.025
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.025
|
|
|
|
regulation of cell activation
|
GO:0050865 |
1 |
0.025
|
|
|
|
membrane invagination
|
GO:0010324 |
1 |
0.025
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
3 |
0.025
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.025
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
52 |
0.025
|
Worm |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.025
|
|
|
|
protein acylation
|
GO:0043543 |
3 |
0.025
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.024
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.024
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.024
|
|
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.024
|
Zebrafish |
|
|
negative regulation of reproductive process
|
GO:2000242 |
3 |
0.024
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
2 |
0.024
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.024
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
62 |
0.024
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
48 |
0.024
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
2 |
0.024
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
1 |
0.024
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
1 |
0.023
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
53 |
0.023
|
|
|
|
negative regulation of small gtpase mediated signal transduction
|
GO:0051058 |
1 |
0.023
|
|
|
|
regulation of establishment or maintenance of cell polarity
|
GO:0032878 |
2 |
0.023
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
3 |
0.023
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.022
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.022
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
97 |
0.022
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.022
|
Fly |
|
|
angiogenesis
|
GO:0001525 |
158 |
0.022
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
42 |
0.022
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.022
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
1 |
0.022
|
|
|
|
segmentation
|
GO:0035282 |
97 |
0.022
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
3 |
0.022
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.022
|
|
|
|
liver development
|
GO:0001889 |
96 |
0.022
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
129 |
0.022
|
Zebrafish |
|
|
response to wounding
|
GO:0009611 |
116 |
0.021
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.021
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
7 |
0.021
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.021
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
45 |
0.021
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
55 |
0.021
|
|
|
|
post embryonic organ development
|
GO:0048569 |
4 |
0.021
|
Worm |
|
|
rna localization
|
GO:0006403 |
4 |
0.021
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.021
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
48 |
0.021
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
108 |
0.020
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
61 |
0.020
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.020
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
27 |
0.020
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.020
|
|
|
|
mitotic cell cycle embryonic
|
GO:0045448 |
2 |
0.020
|
|
|
|
retinoic acid receptor signaling pathway
|
GO:0048384 |
16 |
0.020
|
|
|
|
regulation of transcription from rna polymerase iii promoter
|
GO:0006359 |
1 |
0.020
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
1 |
0.020
|
|
|
|
connective tissue development
|
GO:0061448 |
99 |
0.020
|
|
|
|
pigmentation
|
GO:0043473 |
85 |
0.019
|
|
|
|
neural tube patterning
|
GO:0021532 |
33 |
0.019
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.019
|
|
|
|
striated muscle cell development
|
GO:0055002 |
108 |
0.019
|
|
|
|
cellular respiration
|
GO:0045333 |
3 |
0.019
|
|
|
|
death
|
GO:0016265 |
121 |
0.019
|
Worm |
|
|
response to radiation
|
GO:0009314 |
51 |
0.019
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.019
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
4 |
0.019
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
71 |
0.019
|
Human Fly |
|
|
epithelial cell morphogenesis
|
GO:0003382 |
2 |
0.019
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.019
|
|
|
|
wound healing
|
GO:0042060 |
90 |
0.019
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
4 |
0.019
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.019
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
28 |
0.019
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
4 |
0.019
|
|
|
|
tissue regeneration
|
GO:0042246 |
74 |
0.018
|
|
|
|
regeneration
|
GO:0031099 |
91 |
0.018
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.018
|
|
|
|
fin development
|
GO:0033333 |
77 |
0.018
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
38 |
0.018
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
53 |
0.018
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
2 |
0.018
|
|
|
|
germ line stem cell division
|
GO:0042078 |
1 |
0.018
|
|
|
|
response to bacterium
|
GO:0009617 |
58 |
0.018
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.018
|
|
|
|
stem cell development
|
GO:0048864 |
82 |
0.018
|
|
|
|
b cell activation
|
GO:0042113 |
2 |
0.018
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.018
|
Worm |
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
23 |
0.018
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.018
|
|
|
|
gtp catabolic process
|
GO:0006184 |
2 |
0.017
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.017
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
3 |
0.017
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
4 |
0.017
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
24 |
0.017
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
2 |
0.017
|
|
|
|
cartilage development
|
GO:0051216 |
96 |
0.017
|
|
|
|
head development
|
GO:0060322 |
303 |
0.017
|
|
|
|
epidermis development
|
GO:0008544 |
48 |
0.017
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.017
|
|
|
|
cytokinesis
|
GO:0000910 |
3 |
0.017
|
|
|
|
histone modification
|
GO:0016570 |
20 |
0.016
|
|
|
|
chemosensory behavior
|
GO:0007635 |
1 |
0.016
|
|
|
|
gene silencing
|
GO:0016458 |
4 |
0.016
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
20 |
0.016
|
|
|
|
skin development
|
GO:0043588 |
54 |
0.016
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
2 |
0.016
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.016
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
30 |
0.016
|
|
|
|
epithelium migration
|
GO:0090132 |
25 |
0.016
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
3 |
0.016
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
56 |
0.016
|
|
|
|
establishment of epithelial cell polarity
|
GO:0090162 |
2 |
0.016
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
93 |
0.016
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
98 |
0.016
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
46 |
0.016
|
Human |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
2 |
0.016
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
86 |
0.016
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
108 |
0.016
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
36 |
0.016
|
|
|
|
cell projection assembly
|
GO:0030031 |
64 |
0.016
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.016
|
Worm |
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.016
|
|
|
|
somitogenesis
|
GO:0001756 |
87 |
0.016
|
|
|
|
phagocytosis engulfment
|
GO:0006911 |
1 |
0.016
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.015
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
1 |
0.015
|
|
|
|
fertilization
|
GO:0009566 |
3 |
0.015
|
|
|
|
stem cell division
|
GO:0017145 |
1 |
0.015
|
|
|
|
appendage development
|
GO:0048736 |
80 |
0.015
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
3 |
0.015
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
1 |
0.015
|
|
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
2 |
0.015
|
|
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.015
|
Zebrafish |
|
|
regulation of protein polymerization
|
GO:0032271 |
2 |
0.015
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
53 |
0.015
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
14 |
0.015
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
46 |
0.015
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.015
|
|
|
|
muscle cell development
|
GO:0055001 |
115 |
0.015
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.015
|
|
|
|
telomere organization
|
GO:0032200 |
1 |
0.015
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
1 |
0.014
|
Fly |
|
|
electron transport chain
|
GO:0022900 |
2 |
0.014
|
|
|
|
centrosome organization
|
GO:0051297 |
1 |
0.014
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
4 |
0.014
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
16 |
0.014
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
2 |
0.014
|
|
|
|
gtp metabolic process
|
GO:0046039 |
4 |
0.014
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
4 |
0.014
|
|
|
|
organ formation
|
GO:0048645 |
17 |
0.014
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
2 |
0.014
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
4 |
0.014
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.014
|
Zebrafish |
|
|
positive regulation of histone modification
|
GO:0031058 |
1 |
0.014
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.014
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.014
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
38 |
0.014
|
|
|
|
histone methylation
|
GO:0016571 |
13 |
0.014
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.014
|
|
|
|
actin filament polymerization
|
GO:0030041 |
2 |
0.014
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.014
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.014
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
1 |
0.014
|
|
|
|
protein alkylation
|
GO:0008213 |
13 |
0.013
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
87 |
0.013
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.013
|
Fly |
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.013
|
|
|
|
mesoderm development
|
GO:0007498 |
88 |
0.013
|
|
|
|
germ line stem cell maintenance
|
GO:0030718 |
2 |
0.013
|
|
|
|
hindbrain development
|
GO:0030902 |
91 |
0.013
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
2 |
0.013
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.013
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
4 |
0.013
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
2 |
0.013
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
33 |
0.013
|
|
|
|
regulation of alternative mrna splicing via spliceosome
|
GO:0000381 |
1 |
0.013
|
|
|
|
meiosis i
|
GO:0007127 |
1 |
0.013
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
4 |
0.013
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.013
|
|
|
|
mitochondrion organization
|
GO:0007005 |
4 |
0.013
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.013
|
Fly |
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.013
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
67 |
0.013
|
|
|
|
catabolic process
|
GO:0009056 |
32 |
0.013
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.013
|
Fly |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
107 |
0.013
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
1 |
0.013
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.013
|
|
|
|
cell maturation
|
GO:0048469 |
23 |
0.013
|
|
|
|
alternative mrna splicing via spliceosome
|
GO:0000380 |
1 |
0.013
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.012
|
Worm Fly |
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.012
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
1 |
0.012
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
1 |
0.012
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
2 |
0.012
|
|
|
|
cytoplasm organization
|
GO:0007028 |
4 |
0.012
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
42 |
0.012
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.012
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
3 |
0.012
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
1 |
0.012
|
|
|
|
regulation of dna replication
|
GO:0006275 |
3 |
0.012
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
4 |
0.012
|
|
|
|
histone deacetylation
|
GO:0016575 |
2 |
0.012
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
2 |
0.012
|
|
|
|
atp catabolic process
|
GO:0006200 |
4 |
0.012
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.012
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
90 |
0.012
|
|
|
|
spermatid development
|
GO:0007286 |
2 |
0.012
|
|
|
|
heart looping
|
GO:0001947 |
94 |
0.012
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.012
|
|
|
|
epithelial cell migration
|
GO:0010631 |
25 |
0.012
|
|
|
|
protein complex disassembly
|
GO:0043241 |
1 |
0.012
|
Human |
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
2 |
0.012
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
1 |
0.012
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
79 |
0.011
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
3 |
0.011
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.011
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
44 |
0.011
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.011
|
|
|
|
nucleic acid transport
|
GO:0050657 |
2 |
0.011
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
30 |
0.011
|
|
|
|
protein complex assembly
|
GO:0006461 |
30 |
0.011
|
|
|
|
mitochondrial transport
|
GO:0006839 |
2 |
0.011
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
2 |
0.011
|
|
