Danio rerio

0 known processes

smc2

structural maintenance of chromosomes 2

(Aliases: fb92e05,zgc:55326,SMC2L1,zeh1628,wu:fb92e05)

smc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic nuclear division GO:0007126 4 0.637
Yeast Mouse
regulation of histone h3 k9 methylation GO:0051570 2 0.267
mitotic sister chromatid cohesion GO:0007064 2 0.234
mitotic cell cycle GO:0000278 64 0.231
Human Yeast Worm Fly
meiotic cell cycle process GO:1903046 3 0.190
Yeast Mouse
double strand break repair GO:0006302 3 0.189
negative regulation of histone methylation GO:0031061 1 0.177
dna methylation on cytosine GO:0032776 3 0.172
mitotic sister chromatid segregation GO:0000070 6 0.153
Human Yeast Worm Fly
negative regulation of biological process GO:0048519 304 0.152
Yeast
chromosome organization GO:0051276 31 0.128
Human Yeast Mouse Worm Fly
positive regulation of cell cycle GO:0045787 3 0.123
chromosome organization involved in meiosis GO:0070192 1 0.116
Mouse
meiotic chromosome segregation GO:0045132 3 0.106
Mouse
dna metabolic process GO:0006259 27 0.103
Human Yeast Mouse Worm Fly
nucleic acid metabolic process GO:0090304 244 0.102
Human Yeast Mouse Worm Fly
sister chromatid segregation GO:0000819 6 0.096
Human Yeast Worm Fly
regulation of primary metabolic process GO:0080090 311 0.091
Yeast
larval development GO:0002164 2 0.084
Worm
biosynthetic process GO:0009058 294 0.080
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.080
Yeast
heterocycle metabolic process GO:0046483 290 0.080
Human Yeast Mouse Worm Fly
single organism metabolic process GO:0044710 217 0.078
Human Yeast Mouse Worm Fly
cellular aromatic compound metabolic process GO:0006725 295 0.077
Human Yeast Mouse Worm Fly
sister chromatid cohesion GO:0007062 2 0.070
negative regulation of macromolecule metabolic process GO:0010605 76 0.066
Yeast
regulation of multicellular organism growth GO:0040014 4 0.066
ubiquitin dependent protein catabolic process GO:0006511 3 0.065
organelle fission GO:0048285 23 0.065
Human Yeast Mouse Worm Fly
camera type eye development GO:0043010 222 0.065
cellular macromolecule metabolic process GO:0044260 391 0.063
Human Yeast Mouse Worm Fly
regulation of dna replication GO:0006275 3 0.062
multicellular organism growth GO:0035264 4 0.060
eye development GO:0001654 277 0.058
cellular protein catabolic process GO:0044257 4 0.057
aging GO:0007568 2 0.057
regulation of cellular biosynthetic process GO:0031326 245 0.057
cytokinesis GO:0000910 3 0.056
nucleobase containing compound metabolic process GO:0006139 274 0.056
Human Yeast Mouse Worm Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.055
Yeast
neuroblast proliferation GO:0007405 2 0.055
chromosome segregation GO:0007059 12 0.055
Human Yeast Mouse Worm Fly
epithelial cell differentiation GO:0030855 116 0.052
oocyte maturation GO:0001556 4 0.052
neuron development GO:0048666 262 0.051
digestive system development GO:0055123 289 0.050
cellular nitrogen compound metabolic process GO:0034641 290 0.049
Human Yeast Mouse Worm Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.048
Yeast
signal transduction GO:0007165 455 0.047
organic substance biosynthetic process GO:1901576 289 0.047
negative regulation of dna metabolic process GO:0051053 4 0.047
retina morphogenesis in camera type eye GO:0060042 79 0.047
negative regulation of nucleic acid templated transcription GO:1903507 45 0.046
ribonucleoside monophosphate catabolic process GO:0009158 4 0.046
Yeast
regulation of macromolecule metabolic process GO:0060255 317 0.045
Yeast Worm
stem cell proliferation GO:0072089 4 0.044
nucleoside monophosphate catabolic process GO:0009125 4 0.043
Yeast
mitotic nuclear division GO:0007067 18 0.042
Human Yeast Worm Fly
cellular respiration GO:0045333 3 0.042
negative regulation of cell division GO:0051782 4 0.041
Yeast
production of molecular mediator of immune response GO:0002440 2 0.040
cell projection organization GO:0030030 284 0.039
embryo development ending in birth or egg hatching GO:0009792 271 0.039
Worm
retina development in camera type eye GO:0060041 146 0.039
negative regulation of biosynthetic process GO:0009890 55 0.038
spindle assembly involved in mitosis GO:0090307 1 0.038
organic cyclic compound metabolic process GO:1901360 301 0.038
Human Yeast Mouse Worm Fly
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.038
positive regulation of biological process GO:0048518 253 0.038
cell fate commitment GO:0045165 99 0.038
stem cell maintenance GO:0019827 4 0.037
regulation of gene expression GO:0010468 265 0.035
Worm
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.035
death GO:0016265 121 0.034
centrosome organization GO:0051297 1 0.033
nuclear division GO:0000280 23 0.033
Human Yeast Mouse Worm Fly
regeneration GO:0031099 91 0.033
negative regulation of cellular biosynthetic process GO:0031327 55 0.032
guanosine containing compound metabolic process GO:1901068 4 0.032
homeostatic process GO:0042592 142 0.031
central nervous system development GO:0007417 387 0.031
regulation of apoptotic process GO:0042981 98 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.030
maintenance of location GO:0051235 4 0.030
regulation of cellular metabolic process GO:0031323 320 0.029
Yeast
mitotic metaphase plate congression GO:0007080 1 0.029
macromolecular complex assembly GO:0065003 35 0.029
regulation of gene expression epigenetic GO:0040029 11 0.029
Worm
sensory organ development GO:0007423 393 0.029
cytoskeleton organization GO:0007010 96 0.028
Fly
blood circulation GO:0008015 87 0.028
gene expression GO:0010467 252 0.028
Worm
positive regulation of catabolic process GO:0009896 4 0.028
immune system development GO:0002520 191 0.027
organonitrogen compound metabolic process GO:1901564 74 0.027
Yeast
negative regulation of histone modification GO:0031057 1 0.027
generation of neurons GO:0048699 385 0.027
camera type eye morphogenesis GO:0048593 108 0.027
cilium morphogenesis GO:0060271 85 0.027
dna catabolic process GO:0006308 1 0.027
negative regulation of cellular process GO:0048523 283 0.027
Yeast
negative regulation of chromosome organization GO:2001251 1 0.026
chordate embryonic development GO:0043009 271 0.026
regulation of purine nucleotide catabolic process GO:0033121 2 0.026
hematopoietic or lymphoid organ development GO:0048534 191 0.025
regulation of protein catabolic process GO:0042176 1 0.025
positive regulation of chromatin modification GO:1903310 1 0.025
macromolecule biosynthetic process GO:0009059 227 0.025
mitotic dna integrity checkpoint GO:0044774 4 0.025
organic substance catabolic process GO:1901575 28 0.024
Yeast
hepaticobiliary system development GO:0061008 98 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
neural retina development GO:0003407 49 0.024
regulation of signaling GO:0023051 235 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
Human Yeast Mouse Worm Fly
regulation of protein complex assembly GO:0043254 3 0.024
nucleic acid templated transcription GO:0097659 181 0.024
nuclear migration GO:0007097 3 0.023
organelle organization GO:0006996 227 0.023
Human Yeast Mouse Worm Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.023
heterocycle biosynthetic process GO:0018130 215 0.023
atp catabolic process GO:0006200 4 0.023
Yeast
guanosine containing compound catabolic process GO:1901069 2 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
cell motility GO:0048870 244 0.022
Worm
fertilization GO:0009566 3 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
single organism organelle organization GO:1902589 199 0.022
Human Yeast Mouse Worm Fly
negative regulation of signal transduction GO:0009968 94 0.022
negative regulation of chromatin modification GO:1903309 1 0.022
retina layer formation GO:0010842 24 0.021
programmed cell death GO:0012501 119 0.021
positive regulation of histone modification GO:0031058 1 0.021
dna alkylation GO:0006305 8 0.021
centrosome cycle GO:0007098 1 0.021
apoptotic process GO:0006915 116 0.021
locomotion GO:0040011 313 0.021
Worm
negative regulation of cell cycle GO:0045786 14 0.021
Yeast
cellular biosynthetic process GO:0044249 286 0.020
regulation of intracellular signal transduction GO:1902531 57 0.020
response to amino acid GO:0043200 2 0.020
localization of cell GO:0051674 244 0.020
Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
multi organism process GO:0051704 134 0.020
sensory organ morphogenesis GO:0090596 200 0.020
regulation of metabolic process GO:0019222 359 0.020
Yeast Worm
phagocytosis GO:0006909 3 0.020
regulation of biosynthetic process GO:0009889 250 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
Yeast
regulation of dna metabolic process GO:0051052 11 0.019
cell migration GO:0016477 237 0.019
Worm
regulation of cell communication GO:0010646 232 0.019
muscle structure development GO:0061061 196 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
Mouse Fly
negative regulation of gene expression GO:0010629 65 0.019
regulation of histone methylation GO:0031060 3 0.019
female meiosis chromosome segregation GO:0016321 1 0.019
gtp metabolic process GO:0046039 4 0.018
cell death GO:0008219 121 0.018
regulation of mitotic cell cycle GO:0007346 25 0.018
regulation of chromosome segregation GO:0051983 1 0.018
spindle assembly GO:0051225 2 0.018
cell cycle GO:0007049 93 0.018
Human Yeast Mouse Worm Fly
negative regulation of metabolic process GO:0009892 86 0.017
Yeast
pyrimidine containing compound metabolic process GO:0072527 3 0.017
immune system process GO:0002376 241 0.017
regulation of cell cycle phase transition GO:1901987 8 0.017
pharyngeal system development GO:0060037 18 0.017
regulation of cell activation GO:0050865 1 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
growth GO:0040007 174 0.017
mitotic g2 dna damage checkpoint GO:0007095 3 0.017
mitotic cell cycle process GO:1903047 48 0.016
Human Yeast Worm Fly
negative regulation of cellular metabolic process GO:0031324 77 0.016
Yeast
positive regulation of chromosome organization GO:2001252 1 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
negative regulation of dna replication GO:0008156 2 0.016
protein polymerization GO:0051258 4 0.016
regulation of response to stimulus GO:0048583 269 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
intracellular signal transduction GO:0035556 85 0.015
cellular component biogenesis GO:0044085 178 0.015
dna biosynthetic process GO:0071897 3 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
neuron differentiation GO:0030182 353 0.015
response to other organism GO:0051707 97 0.015
cellular catabolic process GO:0044248 27 0.015
Yeast
negative regulation of signaling GO:0023057 96 0.014
leukocyte proliferation GO:0070661 1 0.014
regulation of programmed cell death GO:0043067 101 0.014
regulation of gene silencing GO:0060968 1 0.014
protein complex localization GO:0031503 1 0.014
single organism biosynthetic process GO:0044711 71 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
tissue regeneration GO:0042246 74 0.014
regulation of transcription dna templated GO:0006355 213 0.014
pancreas development GO:0031016 84 0.014
male meiosis GO:0007140 2 0.014
pronuclear migration GO:0035046 1 0.014
cleavage furrow formation GO:0036089 2 0.014
chromosome localization GO:0050000 2 0.013
regulation of protein transport GO:0051223 3 0.013
hemopoiesis GO:0030097 183 0.013
somatic cell dna recombination GO:0016444 1 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
Yeast
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
macromolecule modification GO:0043412 111 0.013
regulation of biological quality GO:0065008 263 0.013
neuron projection development GO:0031175 180 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
cellular component disassembly GO:0022411 1 0.013
negative regulation of mitosis GO:0045839 3 0.013
positive regulation of cell division GO:0051781 2 0.012
cell cycle process GO:0022402 53 0.012
Human Yeast Mouse Worm Fly
cell proliferation GO:0008283 80 0.012
liver development GO:0001889 96 0.012
centrosome duplication GO:0051298 1 0.012
positive regulation of cell activation GO:0050867 1 0.012
protein import GO:0017038 3 0.012
axon ensheathment in central nervous system GO:0032291 2 0.012
meiosis i GO:0007127 1 0.012
Yeast
cellular component movement GO:0006928 335 0.012
Worm
cell aging GO:0007569 2 0.012
negative regulation of cell cycle phase transition GO:1901988 5 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
regulation of metal ion transport GO:0010959 4 0.012
positive regulation of immune effector process GO:0002699 3 0.012
female meiotic division GO:0007143 2 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
stem cell division GO:0017145 1 0.011
single fertilization GO:0007338 3 0.011
negative regulation of muscle cell differentiation GO:0051148 1 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
regulation of rna metabolic process GO:0051252 224 0.011
microtubule organizing center organization GO:0031023 1 0.011
regulation of cell death GO:0010941 103 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
meiosis ii GO:0007135 1 0.011
dna modification GO:0006304 8 0.011
lipid homeostasis GO:0055088 3 0.010
negative regulation of protein kinase activity GO:0006469 4 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
Yeast
single organism transport GO:0044765 206 0.010
mononuclear cell proliferation GO:0032943 1 0.010
meiotic spindle organization GO:0000212 1 0.010
microtubule based process GO:0007017 60 0.010
Fly
negative regulation of cell death GO:0060548 60 0.010
rna localization GO:0006403 4 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
transport GO:0006810 220 0.010

smc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.025
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.025
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011