Danio rerio

39 known processes

smg6

Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)

(Aliases: si:dkey-16f21.2)

smg6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.398
cellular macromolecule metabolic process GO:0044260 391 0.092
mrna catabolic process GO:0006402 6 0.086
cellular nitrogen compound metabolic process GO:0034641 290 0.086
rna catabolic process GO:0006401 7 0.067
cellular aromatic compound metabolic process GO:0006725 295 0.058
rna metabolic process GO:0016070 219 0.056
aging GO:0007568 2 0.052
gtp metabolic process GO:0046039 4 0.051
nitrogen compound metabolic process GO:0006807 319 0.051
larval development GO:0002164 2 0.049
nuclear transcribed mrna catabolic process GO:0000956 4 0.049
organic cyclic compound metabolic process GO:1901360 301 0.040
heterocycle metabolic process GO:0046483 290 0.036
multicellular organism growth GO:0035264 4 0.035
nucleic acid metabolic process GO:0090304 244 0.035
positive regulation of transport GO:0051050 2 0.034
guanosine containing compound metabolic process GO:1901068 4 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.030
single fertilization GO:0007338 3 0.030
organic substance biosynthetic process GO:1901576 289 0.029
regulation of cellular metabolic process GO:0031323 320 0.029
regulation of synapse organization GO:0050807 3 0.028
biosynthetic process GO:0009058 294 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
phagocytosis GO:0006909 3 0.027
macromolecule biosynthetic process GO:0009059 227 0.027
modification dependent protein catabolic process GO:0019941 3 0.026
phosphate containing compound metabolic process GO:0006796 108 0.026
maintenance of location GO:0051235 4 0.026
guanosine containing compound catabolic process GO:1901069 2 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
cellular amine metabolic process GO:0044106 2 0.025
positive regulation of translation GO:0045727 1 0.025
regulation of reproductive process GO:2000241 4 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.025
cellular macromolecule catabolic process GO:0044265 12 0.025
transport GO:0006810 220 0.024
response to chemical GO:0042221 320 0.024
stem cell maintenance GO:0019827 4 0.024
cellular component movement GO:0006928 335 0.024
locomotion GO:0040011 313 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
single organism metabolic process GO:0044710 217 0.024
fertilization GO:0009566 3 0.023
small molecule metabolic process GO:0044281 77 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
lipid storage GO:0019915 1 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
gtp catabolic process GO:0006184 2 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
regulation of metabolic process GO:0019222 359 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
negative regulation of biological process GO:0048519 304 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
protein localization to nucleus GO:0034504 3 0.022
eye development GO:0001654 277 0.022
cellular ketone metabolic process GO:0042180 11 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
protein metabolic process GO:0019538 183 0.022
amine metabolic process GO:0009308 2 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.021
cellular response to external stimulus GO:0071496 2 0.021
cellular response to lipopolysaccharide GO:0071222 3 0.021
regionalization GO:0003002 274 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.020
cellular nitrogen compound catabolic process GO:0044270 15 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
response to carbohydrate GO:0009743 3 0.020
atp catabolic process GO:0006200 4 0.020
heart development GO:0007507 313 0.020
regulation of gene expression GO:0010468 265 0.020
signal transduction GO:0007165 455 0.020
oxoacid metabolic process GO:0043436 31 0.020
gene expression GO:0010467 252 0.020
retina development in camera type eye GO:0060041 146 0.020
regulation of primary metabolic process GO:0080090 311 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.019
sensory organ development GO:0007423 393 0.019
single organism localization GO:1902578 225 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
regulation of synapse assembly GO:0051963 3 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
camera type eye development GO:0043010 222 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
head development GO:0060322 303 0.019
peptidyl serine modification GO:0018209 2 0.018
stem cell proliferation GO:0072089 4 0.018
cellular biosynthetic process GO:0044249 286 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
cellular protein catabolic process GO:0044257 4 0.018
interspecies interaction between organisms GO:0044419 4 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
nucleoside monophosphate catabolic process GO:0009125 4 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
rna localization GO:0006403 4 0.018
hepaticobiliary system development GO:0061008 98 0.018
establishment of localization GO:0051234 244 0.018
organic acid metabolic process GO:0006082 31 0.018
vasculature development GO:0001944 278 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
autophagy GO:0006914 4 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
negative regulation of kinase activity GO:0033673 4 0.017
cellular protein metabolic process GO:0044267 129 0.017
negative regulation of map kinase activity GO:0043407 2 0.017
regulation of cell activation GO:0050865 1 0.017
meiotic nuclear division GO:0007126 4 0.017
cellular response to nutrient levels GO:0031669 2 0.017
regulation of dendrite development GO:0050773 3 0.017
negative regulation of cellular catabolic process GO:0031330 3 0.017
nuclear transport GO:0051169 4 0.017
positive regulation of catabolic process GO:0009896 4 0.016
determination of bilateral symmetry GO:0009855 204 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
embryonic organ development GO:0048568 381 0.016
cellular response to biotic stimulus GO:0071216 3 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
response to stress GO:0006950 263 0.016
muscle structure development GO:0061061 196 0.016
pronuclear migration GO:0035046 1 0.016
central nervous system development GO:0007417 387 0.016
protein import GO:0017038 3 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
chordate embryonic development GO:0043009 271 0.016
organic cyclic compound catabolic process GO:1901361 15 0.016
response to glucose GO:0009749 3 0.016
negative regulation of catabolic process GO:0009895 3 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
regulation of signal transduction GO:0009966 225 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
apoptotic process involved in development GO:1902742 2 0.015
regulation of binding GO:0051098 3 0.015
regulation of protein catabolic process GO:0042176 1 0.015
neurotransmitter transport GO:0006836 2 0.015
cell projection organization GO:0030030 284 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
response to hexose GO:0009746 3 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
regulation of gtpase activity GO:0043087 2 0.015
localization of cell GO:0051674 244 0.015
b cell activation GO:0042113 2 0.015
positive regulation of cell cycle GO:0045787 3 0.015
regulation of neurotransmitter secretion GO:0046928 1 0.015
single organism transport GO:0044765 206 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
embryonic skeletal system development GO:0048706 97 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
phosphorus metabolic process GO:0006793 109 0.015
response to monosaccharide GO:0034284 3 0.015
hormone secretion GO:0046879 2 0.015
response to corticosteroid GO:0031960 1 0.015
organelle fusion GO:0048284 3 0.014
tube morphogenesis GO:0035239 349 0.014
cellular component disassembly GO:0022411 1 0.014
blood vessel development GO:0001568 246 0.014
neuron differentiation GO:0030182 353 0.014
regulation of cytokine production GO:0001817 3 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
brain development GO:0007420 293 0.014
protein stabilization GO:0050821 2 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
transcription dna templated GO:0006351 181 0.014
regulation of biological quality GO:0065008 263 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
striated muscle tissue development GO:0014706 110 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
specification of symmetry GO:0009799 204 0.014
cellular component morphogenesis GO:0032989 336 0.014
positive regulation of cellular process GO:0048522 201 0.014
regulation of protein transport GO:0051223 3 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
cell substrate adhesion GO:0031589 4 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
nucleic acid templated transcription GO:0097659 181 0.013
mesenchyme development GO:0060485 127 0.013
lipid metabolic process GO:0006629 52 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
cell migration GO:0016477 237 0.013
mitochondrion organization GO:0007005 4 0.013
system process GO:0003008 185 0.013
response to uv GO:0009411 3 0.013
generation of neurons GO:0048699 385 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
positive regulation of secretion GO:0051047 1 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
tube closure GO:0060606 1 0.013
mrna metabolic process GO:0016071 20 0.013
macromolecular complex disassembly GO:0032984 1 0.013
determination of left right symmetry GO:0007368 179 0.013
protein localization to plasma membrane GO:0072659 1 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
macromolecule modification GO:0043412 111 0.013
digestive tract development GO:0048565 265 0.013
endothelial cell fate commitment GO:0060839 3 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
positive regulation of immune effector process GO:0002699 3 0.013
translational initiation GO:0006413 3 0.013
odontogenesis of dentin containing tooth GO:0042475 1 0.013
sensory perception of chemical stimulus GO:0007606 3 0.013
regulation of response to stimulus GO:0048583 269 0.013
regulation of developmental process GO:0050793 247 0.013
cellular response to starvation GO:0009267 1 0.013
digestive system development GO:0055123 289 0.013
peptide transport GO:0015833 1 0.013
nuclear import GO:0051170 3 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
eye morphogenesis GO:0048592 144 0.012
establishment of rna localization GO:0051236 3 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
exocytosis GO:0006887 1 0.012
endosomal transport GO:0016197 2 0.012
axon development GO:0061564 166 0.012
response to nutrient GO:0007584 3 0.012
gland development GO:0048732 143 0.012
amino acid transport GO:0006865 2 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
multicellular organismal signaling GO:0035637 22 0.012
single organism organelle organization GO:1902589 199 0.012
somatic stem cell maintenance GO:0035019 1 0.012
primary neural tube formation GO:0014020 1 0.012
protein modification process GO:0036211 100 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
cell motility GO:0048870 244 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
response to glucocorticoid GO:0051384 1 0.012
viral process GO:0016032 1 0.012
organelle organization GO:0006996 227 0.012
post embryonic organ development GO:0048569 4 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
negative regulation of nuclear division GO:0051784 3 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
response to external stimulus GO:0009605 264 0.011
regulation of hormone secretion GO:0046883 2 0.011
endocrine process GO:0050886 2 0.011
regulation of biomineral tissue development GO:0070167 2 0.011
adult behavior GO:0030534 2 0.011
cellular protein modification process GO:0006464 100 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
meiotic cell cycle process GO:1903046 3 0.011
rna transport GO:0050658 2 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
glucose homeostasis GO:0042593 1 0.011
developmental programmed cell death GO:0010623 4 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
negative regulation of cellular process GO:0048523 283 0.011
protein polymerization GO:0051258 4 0.011
regulation of cell communication GO:0010646 232 0.011
hormone transport GO:0009914 2 0.011
regulation of mrna processing GO:0050684 3 0.011
renal system development GO:0072001 94 0.011
ear development GO:0043583 127 0.011
cellular response to oxygen levels GO:0071453 1 0.011
single organism membrane fusion GO:0044801 2 0.011
nucleobase containing compound catabolic process GO:0034655 15 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
protein targeting to nucleus GO:0044744 3 0.011
single organism nuclear import GO:1902593 3 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
compound eye development GO:0048749 2 0.011
rna biosynthetic process GO:0032774 181 0.011
regulation of cell shape GO:0008360 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
ameboidal type cell migration GO:0001667 143 0.011
nuclear migration GO:0007097 3 0.011
regulation of biosynthetic process GO:0009889 250 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
protein import into nucleus GO:0006606 3 0.011
positive regulation of cytokine production GO:0001819 2 0.011
mononuclear cell proliferation GO:0032943 1 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
tissue remodeling GO:0048771 4 0.011
transmembrane transport GO:0055085 120 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
positive regulation of synapse assembly GO:0051965 1 0.011
protein homooligomerization GO:0051260 3 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
transmission of nerve impulse GO:0019226 19 0.011
cellular component biogenesis GO:0044085 178 0.010
membrane invagination GO:0010324 1 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
cell part morphogenesis GO:0032990 246 0.010
protein complex disassembly GO:0043241 1 0.010
regulation of cell death GO:0010941 103 0.010
centrosome organization GO:0051297 1 0.010
regulation of protein complex assembly GO:0043254 3 0.010
somatic muscle development GO:0007525 4 0.010
sensory organ morphogenesis GO:0090596 200 0.010
regulation of bone mineralization GO:0030500 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
gastrulation GO:0007369 208 0.010
cell morphogenesis GO:0000902 289 0.010
carboxylic acid catabolic process GO:0046395 3 0.010
response to drug GO:0042493 3 0.010
cell projection morphogenesis GO:0048858 244 0.010
ventricular cardiac muscle tissue development GO:0003229 3 0.010
heart morphogenesis GO:0003007 156 0.010

smg6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
disease of metabolism DOID:0014667 0 0.023
musculoskeletal system disease DOID:17 0 0.016
immune system disease DOID:2914 0 0.014
inherited metabolic disorder DOID:655 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.011
cardiovascular system disease DOID:1287 0 0.011
organ system cancer DOID:0050686 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
nervous system disease DOID:863 0 0.011
eye disease DOID:5614 0 0.011