Danio rerio

107 known processes

socs3a

suppressor of cytokine signaling 3a

(Aliases: zgc:56537,fj09e12,socs3,wu:fj09e12)

socs3a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 97 0.857
Rat
camera type eye development GO:0043010 222 0.831
tyrosine phosphorylation of stat protein GO:0007260 1 0.773
response to bacterium GO:0009617 58 0.762
Rat
regulation of cellular metabolic process GO:0031323 320 0.755
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.749
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.745
response to lipid GO:0033993 60 0.706
Rat
regulation of biosynthetic process GO:0009889 250 0.696
nucleobase containing compound biosynthetic process GO:0034654 205 0.689
negative regulation of response to cytokine stimulus GO:0060761 2 0.668
Zebrafish
response to external biotic stimulus GO:0043207 97 0.652
Rat
cellular macromolecule metabolic process GO:0044260 391 0.650
Mouse
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.635
Zebrafish
negative regulation of neuron projection regeneration GO:0070571 4 0.615
regulation of nitrogen compound metabolic process GO:0051171 251 0.615
immune system process GO:0002376 241 0.601
Zebrafish
axon regeneration GO:0031103 14 0.584
cellular biosynthetic process GO:0044249 286 0.582
response to amino acid GO:0043200 2 0.579
regulation of macromolecule biosynthetic process GO:0010556 225 0.579
response to external stimulus GO:0009605 264 0.574
multi organism process GO:0051704 134 0.572
Rat
regulation of metabolic process GO:0019222 359 0.562
Mouse
negative regulation of cellular process GO:0048523 283 0.559
positive regulation of cellular process GO:0048522 201 0.540
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.539
heterocycle biosynthetic process GO:0018130 215 0.529
neuromast hair cell development GO:0035675 6 0.526
neuron projection regeneration GO:0031102 16 0.516
response to virus GO:0009615 21 0.509
nucleobase containing compound metabolic process GO:0006139 274 0.509
antimicrobial humoral response GO:0019730 2 0.485
macromolecule biosynthetic process GO:0009059 227 0.484
posterior lateral line neuromast hair cell development GO:0035677 3 0.480
regulation of macromolecule metabolic process GO:0060255 317 0.471
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.463
response to radiation GO:0009314 51 0.460
Rat
biosynthetic process GO:0009058 294 0.451
regulation of rna biosynthetic process GO:2001141 213 0.450
humoral immune response GO:0006959 5 0.449
transcription from rna polymerase ii promoter GO:0006366 80 0.446
response to lipopolysaccharide GO:0032496 13 0.429
Rat
nitrogen compound metabolic process GO:0006807 319 0.420
interferon gamma mediated signaling pathway GO:0060333 1 0.417
Zebrafish
response to other organism GO:0051707 97 0.411
Rat
heterocycle metabolic process GO:0046483 290 0.409
regulation of primary metabolic process GO:0080090 311 0.405
Mouse
positive regulation of cell death GO:0010942 29 0.402
regulation of jak stat cascade GO:0046425 3 0.396
Zebrafish
response to stress GO:0006950 263 0.391
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.389
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.389
aromatic compound biosynthetic process GO:0019438 217 0.382
organic substance biosynthetic process GO:1901576 289 0.381
intracellular signal transduction GO:0035556 85 0.380
Zebrafish Rat
response to alcohol GO:0097305 14 0.375
Rat
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.373
response to wounding GO:0009611 116 0.370
regeneration GO:0031099 91 0.368
compound eye development GO:0048749 2 0.366
negative regulation of metabolic process GO:0009892 86 0.363
regulation of transcription dna templated GO:0006355 213 0.355
cell surface receptor signaling pathway GO:0007166 325 0.354
Zebrafish Mouse
negative regulation of biological process GO:0048519 304 0.352
sensory organ development GO:0007423 393 0.351
response to light stimulus GO:0009416 46 0.351
cellular nitrogen compound metabolic process GO:0034641 290 0.351
positive regulation of biological process GO:0048518 253 0.346
Mouse
response to ketone GO:1901654 1 0.343
Rat
cell cycle g2 m phase transition GO:0044839 4 0.342
negative regulation of cell projection organization GO:0031345 9 0.330
regulation of interferon gamma mediated signaling pathway GO:0060334 1 0.325
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.322
eye development GO:0001654 277 0.322
cell projection organization GO:0030030 284 0.311
synaptic growth at neuromuscular junction GO:0051124 2 0.307
negative regulation of cellular metabolic process GO:0031324 77 0.293
response to transition metal nanoparticle GO:1990267 28 0.289
regulation of carbohydrate metabolic process GO:0006109 4 0.279
response to dsrna GO:0043331 7 0.277
regulation of multicellular organismal process GO:0051239 277 0.273
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.271
regulation of signaling GO:0023051 235 0.261
Zebrafish Mouse
response to drug GO:0042493 3 0.257
Rat
rna biosynthetic process GO:0032774 181 0.257
locomotor rhythm GO:0045475 3 0.253
response to estradiol GO:0032355 6 0.250
Rat
immune system development GO:0002520 191 0.247
Zebrafish
transcription dna templated GO:0006351 181 0.246
regulation of response to oxidative stress GO:1902882 2 0.239
regulation of response to stimulus GO:0048583 269 0.236
positive regulation of cellular metabolic process GO:0031325 94 0.235
myeloid cell differentiation GO:0030099 86 0.234
positive regulation of myeloid cell differentiation GO:0045639 2 0.232
sexual reproduction GO:0019953 36 0.227
positive regulation of metabolic process GO:0009893 108 0.226
response to organic substance GO:0010033 153 0.223
Zebrafish Mouse Rat
hair cell differentiation GO:0035315 32 0.221
macromolecule modification GO:0043412 111 0.220
Mouse
regulation of phosphorus metabolic process GO:0051174 43 0.216
Mouse
response to molecule of bacterial origin GO:0002237 14 0.214
Rat
activation of mapkkk activity GO:0000185 1 0.212
cellular nitrogen compound biosynthetic process GO:0044271 218 0.212
positive regulation of molecular function GO:0044093 33 0.209
negative regulation of rna metabolic process GO:0051253 48 0.209
response to methylmercury GO:0051597 11 0.206
rna metabolic process GO:0016070 219 0.206
cellular protein modification process GO:0006464 100 0.205
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.203
i kappab kinase nf kappab signaling GO:0007249 4 0.203
phosphorus metabolic process GO:0006793 109 0.202
Mouse
camera type eye morphogenesis GO:0048593 108 0.200
nucleic acid templated transcription GO:0097659 181 0.196
neuron projection development GO:0031175 180 0.191
gene expression GO:0010467 252 0.190
regulation of gene expression GO:0010468 265 0.187
cellular response to external stimulus GO:0071496 2 0.184
regulation of catalytic activity GO:0050790 55 0.183
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.181
single organism metabolic process GO:0044710 217 0.180
neuron projection morphogenesis GO:0048812 161 0.175
amine metabolic process GO:0009308 2 0.171
astrocyte differentiation GO:0048708 1 0.167
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.166
cellular response to endogenous stimulus GO:0071495 68 0.166
Mouse
protein metabolic process GO:0019538 183 0.163
Mouse
generation of neurons GO:0048699 385 0.163
negative regulation of signaling GO:0023057 96 0.161
Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.160
g2 m transition of mitotic cell cycle GO:0000086 4 0.158
mitochondrion organization GO:0007005 4 0.157
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.154
nucleic acid metabolic process GO:0090304 244 0.151
cellular protein metabolic process GO:0044267 129 0.150
Mouse
regulation of binding GO:0051098 3 0.149
cellular ketone metabolic process GO:0042180 11 0.149
cellular response to oxygen containing compound GO:1901701 20 0.149
Mouse
protein modification process GO:0036211 100 0.149
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.148
response to corticosteroid GO:0031960 1 0.144
Rat
response to cadmium ion GO:0046686 14 0.144
regulation of rna metabolic process GO:0051252 224 0.143
positive regulation of macromolecule metabolic process GO:0010604 93 0.140
positive regulation of neuron death GO:1901216 1 0.138
positive regulation of neuron apoptotic process GO:0043525 1 0.138
negative regulation of cellular biosynthetic process GO:0031327 55 0.137
sensory organ morphogenesis GO:0090596 200 0.137
response to abiotic stimulus GO:0009628 122 0.136
Rat
axonogenesis GO:0007409 152 0.134
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.132
positive regulation of signaling GO:0023056 56 0.132
negative regulation of innate immune response GO:0045824 2 0.131
Zebrafish
regulation of cellular response to oxidative stress GO:1900407 2 0.131
regulation of response to biotic stimulus GO:0002831 2 0.129
regulation of response to cytokine stimulus GO:0060759 3 0.128
Zebrafish
regulation of molecular function GO:0065009 70 0.128
positive regulation of cellular component biogenesis GO:0044089 3 0.128
cellular response to chemical stimulus GO:0070887 157 0.126
Zebrafish Mouse
positive regulation of apoptotic signaling pathway GO:2001235 1 0.126
cellular response to lipopolysaccharide GO:0071222 3 0.126
signal transduction GO:0007165 455 0.126
Zebrafish Mouse Rat
positive regulation of developmental process GO:0051094 50 0.125
Mouse
response to hormone GO:0009725 48 0.125
Mouse Rat
cellular carbohydrate metabolic process GO:0044262 4 0.125
response to nitrogen compound GO:1901698 19 0.123
Mouse Rat
negative regulation of protein phosphorylation GO:0001933 4 0.123
positive regulation of immune system process GO:0002684 17 0.121
response to steroid hormone GO:0048545 35 0.121
Rat
mesenchyme development GO:0060485 127 0.120
hematopoietic or lymphoid organ development GO:0048534 191 0.120
Zebrafish
posterior lateral line neuromast development GO:0048919 20 0.119
positive regulation of biosynthetic process GO:0009891 68 0.118
regulation of cellular amino acid metabolic process GO:0006521 0 0.118
aging GO:0007568 2 0.117
Rat
small molecule metabolic process GO:0044281 77 0.116
positive regulation of rna metabolic process GO:0051254 59 0.116
regulation of immune system process GO:0002682 34 0.116
Zebrafish
regulation of nucleoside metabolic process GO:0009118 2 0.115
response to estrogen GO:0043627 27 0.114
Rat
hemopoiesis GO:0030097 183 0.114
Zebrafish
regulation of inflammatory response GO:0050727 2 0.112
Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.111
regulation of multicellular organismal development GO:2000026 223 0.111
negative regulation of biosynthetic process GO:0009890 55 0.111
osteoclast differentiation GO:0030316 1 0.111
positive regulation of cellular biosynthetic process GO:0031328 68 0.110
retina development in camera type eye GO:0060041 146 0.110
phosphate containing compound metabolic process GO:0006796 108 0.107
Mouse
establishment of protein localization to organelle GO:0072594 4 0.107
regulation of oxidative stress induced cell death GO:1903201 2 0.106
synapse assembly GO:0007416 9 0.105
positive regulation of transcription dna templated GO:0045893 57 0.105
visual behavior GO:0007632 10 0.105
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.104
liver development GO:0001889 96 0.104
response to inorganic substance GO:0010035 38 0.104
regulation of endothelial cell proliferation GO:0001936 1 0.103
anterior posterior pattern specification GO:0009952 152 0.103
programmed cell death GO:0012501 119 0.101
organonitrogen compound metabolic process GO:1901564 74 0.100
developmental growth GO:0048589 166 0.100
regulation of axon regeneration GO:0048679 7 0.099
cellular response to molecule of bacterial origin GO:0071219 3 0.098
negative regulation of kinase activity GO:0033673 4 0.096
regulation of cell communication GO:0010646 232 0.095
Zebrafish Mouse
response to chemical GO:0042221 320 0.094
Zebrafish Mouse Rat
regionalization GO:0003002 274 0.094
tissue regeneration GO:0042246 74 0.094
p38mapk cascade GO:0038066 1 0.093
negative regulation of interferon gamma mediated signaling pathway GO:0060336 1 0.093
Zebrafish
regulation of cytokine production GO:0001817 3 0.091
posterior lateral line development GO:0048916 38 0.091
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.091
cognition GO:0050890 1 0.090
growth GO:0040007 174 0.090
negative regulation of macromolecule metabolic process GO:0010605 76 0.090
negative regulation of transcription dna templated GO:0045892 45 0.089
response to axon injury GO:0048678 14 0.089
positive regulation of response to stimulus GO:0048584 80 0.089
regulation of synaptic plasticity GO:0048167 1 0.088
energy reserve metabolic process GO:0006112 2 0.087
skeletal system development GO:0001501 181 0.086
wound healing GO:0042060 90 0.086
organic cyclic compound biosynthetic process GO:1901362 223 0.086
eye morphogenesis GO:0048592 144 0.086
regulation of signal transduction GO:0009966 225 0.086
Zebrafish Mouse
reproductive process GO:0022414 40 0.085
Mouse
response to oxygen containing compound GO:1901700 55 0.085
Mouse Rat
cell death GO:0008219 121 0.085
enzyme linked receptor protein signaling pathway GO:0007167 106 0.085
Mouse
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.085
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.084
negative regulation of gene expression GO:0010629 65 0.084
single organism biosynthetic process GO:0044711 71 0.083
cellular response to hormone stimulus GO:0032870 39 0.083
Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.083
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.083
sleep GO:0030431 1 0.082
negative regulation of rna biosynthetic process GO:1902679 45 0.082
positive regulation of rna biosynthetic process GO:1902680 57 0.082
embryonic hemopoiesis GO:0035162 53 0.082
Zebrafish
cell death in response to oxidative stress GO:0036473 2 0.081
nuclear transport GO:0051169 4 0.081
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.081
neuron differentiation GO:0030182 353 0.080
angiogenesis GO:0001525 158 0.080
nucleocytoplasmic transport GO:0006913 4 0.080
regulation of wound healing GO:0061041 2 0.080
carbohydrate derivative biosynthetic process GO:1901137 43 0.079
phagocytosis GO:0006909 3 0.078
mitotic cell cycle phase transition GO:0044772 9 0.077
positive regulation of cell communication GO:0010647 56 0.077
regulation of nucleotide catabolic process GO:0030811 2 0.077
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.077
positive regulation of gene expression GO:0010628 71 0.076
cellular amine metabolic process GO:0044106 2 0.076
somitogenesis GO:0001756 87 0.075
protein import GO:0017038 3 0.075
response to glucocorticoid GO:0051384 1 0.074
Rat
circadian rhythm GO:0007623 19 0.074
regulation of cellular amine metabolic process GO:0033238 0 0.073
mitotic cell cycle process GO:1903047 48 0.073
negative regulation of map kinase activity GO:0043407 2 0.071
positive regulation of nucleoside metabolic process GO:0045979 1 0.071
negative regulation of cell differentiation GO:0045596 46 0.071
positive regulation of epithelial cell proliferation GO:0050679 1 0.070
regulation of nucleocytoplasmic transport GO:0046822 2 0.070
digestive tract development GO:0048565 265 0.069
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.068
regulation of biological quality GO:0065008 263 0.068
guanosine containing compound metabolic process GO:1901068 4 0.068
cellular response to organic substance GO:0071310 105 0.068
Zebrafish Mouse
mechanosensory lateral line system development GO:0048881 49 0.068
protein import into nucleus GO:0006606 3 0.068
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.066
negative regulation of cell communication GO:0010648 96 0.064
Zebrafish Mouse
protein localization to nucleus GO:0034504 3 0.064
regulation of establishment of protein localization GO:0070201 4 0.064
regulation of response to interferon gamma GO:0060330 1 0.063
Zebrafish
positive regulation of cell proliferation GO:0008284 15 0.062
response to endogenous stimulus GO:0009719 83 0.062
Mouse Rat
sensory system development GO:0048880 76 0.061
regulation of neuron differentiation GO:0045664 56 0.061
regulation of cellular ketone metabolic process GO:0010565 7 0.059
single organism nuclear import GO:1902593 3 0.059
digestive system development GO:0055123 289 0.058
negative regulation of multicellular organismal process GO:0051241 69 0.058
rhythmic process GO:0048511 21 0.057
positive regulation of stress activated mapk cascade GO:0032874 3 0.057
regulation of mitochondrion organization GO:0010821 1 0.057
regulation of developmental process GO:0050793 247 0.057
nephron morphogenesis GO:0072028 2 0.056
regulation of endodermal cell differentiation GO:1903224 15 0.056
monocyte differentiation GO:0030224 2 0.056
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.055
response to organic cyclic compound GO:0014070 51 0.055
Rat
response to mechanical stimulus GO:0009612 24 0.054
positive regulation of cytokine production GO:0001819 2 0.054
cellular response to light stimulus GO:0071482 4 0.054
cellular response to radiation GO:0071478 4 0.053
positive regulation of multicellular organismal process GO:0051240 52 0.053
response to hypoxia GO:0001666 25 0.053
Rat
cellular response to nutrient levels GO:0031669 2 0.053
neuromast development GO:0048884 46 0.052
regulation of protein metabolic process GO:0051246 56 0.051
Mouse
single organism membrane fusion GO:0044801 2 0.051
regulation of p38mapk cascade GO:1900744 1 0.051
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.051
Mouse
cellular response to organic cyclic compound GO:0071407 38 0.050
endocrine system development GO:0035270 65 0.049
cytokine mediated signaling pathway GO:0019221 7 0.049
Zebrafish
central nervous system development GO:0007417 387 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.049
protein targeting to nucleus GO:0044744 3 0.049
hepaticobiliary system development GO:0061008 98 0.048
purine ribonucleoside biosynthetic process GO:0046129 2 0.048
apoptotic process GO:0006915 116 0.048
skeletal muscle organ development GO:0060538 78 0.048
behavior GO:0007610 74 0.048
gland development GO:0048732 143 0.047
cellular response to organonitrogen compound GO:0071417 5 0.047
Mouse
regulation of intracellular signal transduction GO:1902531 57 0.047
Zebrafish
regulation of protein localization to nucleus GO:1900180 2 0.047
multi organism reproductive process GO:0044703 36 0.047
cellular amino acid metabolic process GO:0006520 7 0.046
cellular amide metabolic process GO:0043603 4 0.046
response to carbohydrate GO:0009743 3 0.046
regulation of reactive oxygen species metabolic process GO:2000377 2 0.046
cellular response to peptide hormone stimulus GO:0071375 5 0.046
Mouse
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 1 0.046
carbohydrate metabolic process GO:0005975 12 0.046
regulation of intracellular protein transport GO:0033157 3 0.046
organelle fusion GO:0048284 3 0.046
endodermal cell differentiation GO:0035987 19 0.046
regulation of cell differentiation GO:0045595 142 0.046
regulation of multicellular organism growth GO:0040014 4 0.045
cell migration GO:0016477 237 0.045
developmental cell growth GO:0048588 52 0.044
positive regulation of catabolic process GO:0009896 4 0.044
vasculature development GO:0001944 278 0.044
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.043
positive regulation of gtp catabolic process GO:0033126 1 0.043
primitive erythrocyte differentiation GO:0060319 5 0.043
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.043
telomere organization GO:0032200 1 0.042
organ regeneration GO:0031100 1 0.042
Rat
peptide metabolic process GO:0006518 1 0.042
dorsal ventral pattern formation GO:0009953 125 0.042
response to arsenic containing substance GO:0046685 5 0.042
death GO:0016265 121 0.042
response to organonitrogen compound GO:0010243 12 0.042
Mouse Rat
regulation of cellular protein metabolic process GO:0032268 52 0.041
Mouse
collateral sprouting GO:0048668 9 0.041
positive regulation of endopeptidase activity GO:0010950 10 0.041
tube morphogenesis GO:0035239 349 0.041
primitive hemopoiesis GO:0060215 27 0.040
circadian behavior GO:0048512 5 0.040
mechanoreceptor differentiation GO:0042490 37 0.040
positive regulation of programmed cell death GO:0043068 29 0.040
single organism carbohydrate metabolic process GO:0044723 12 0.040
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.040
regulation of phosphate metabolic process GO:0019220 43 0.040
Mouse
positive regulation of gliogenesis GO:0014015 2 0.039
stem cell proliferation GO:0072089 4 0.039
regulation of protein transport GO:0051223 3 0.039
positive regulation of epithelial cell migration GO:0010634 2 0.038
g1 s transition of mitotic cell cycle GO:0000082 1 0.038
cellular response to oxygen levels GO:0071453 1 0.038
cell proliferation GO:0008283 80 0.038
cellular component assembly GO:0022607 170 0.038
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.038
endoderm formation GO:0001706 29 0.038
outflow tract morphogenesis GO:0003151 1 0.037
lipid storage GO:0019915 1 0.037
positive regulation of blood circulation GO:1903524 2 0.037
regulation of neuron projection development GO:0010975 40 0.037
maintenance of location GO:0051235 4 0.037
regulation of protein phosphorylation GO:0001932 18 0.037
Mouse
response to acid chemical GO:0001101 17 0.037
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.037
ectodermal cell fate specification GO:0001715 2 0.036
regulation of cytoplasmic transport GO:1903649 4 0.036
jak stat cascade GO:0007259 5 0.036
Zebrafish Rat
organic acid metabolic process GO:0006082 31 0.036
guanosine containing compound catabolic process GO:1901069 2 0.036
nuclear import GO:0051170 3 0.036
myeloid cell homeostasis GO:0002262 56 0.035
cell motility GO:0048870 244 0.035
positive regulation of myeloid leukocyte differentiation GO:0002763 1 0.035
viral process GO:0016032 1 0.035
multicellular organism growth GO:0035264 4 0.035
organelle organization GO:0006996 227 0.035
cellular response to lipid GO:0071396 39 0.034
system process GO:0003008 185 0.034
phosphorylation GO:0016310 69 0.034
Mouse
glucose import GO:0046323 2 0.034
positive regulation of transport GO:0051050 2 0.034
neuron development GO:0048666 262 0.034
cellular response to starvation GO:0009267 1 0.033
regulation of phospholipase activity GO:0010517 2 0.033
negative regulation of protein kinase activity GO:0006469 4 0.033
lateral line development GO:0048882 66 0.033
cell growth GO:0016049 57 0.033
response to food GO:0032094 1 0.033
Rat
cellular component biogenesis GO:0044085 178 0.033
positive regulation of response to external stimulus GO:0032103 9 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
cellular response to biotic stimulus GO:0071216 3 0.033
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.033
organophosphate metabolic process GO:0019637 37 0.032
optokinetic behavior GO:0007634 9 0.032
establishment of localization GO:0051234 244 0.032
skeletal muscle tissue development GO:0007519 67 0.032
positive regulation of leukocyte differentiation GO:1902107 1 0.032
positive regulation of gtpase activity GO:0043547 1 0.032
regulation of myeloid cell differentiation GO:0045637 8 0.032
retina morphogenesis in camera type eye GO:0060042 79 0.032
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.032
regulation of tube size GO:0035150 2 0.031
negative regulation of cell death GO:0060548 60 0.031
apoptotic process involved in morphogenesis GO:0060561 2 0.031
negative regulation of intracellular signal transduction GO:1902532 22 0.031
Zebrafish
pancreas development GO:0031016 84 0.031
peptide transport GO:0015833 1 0.031
brain development GO:0007420 293 0.031
immune response GO:0006955 28 0.030
Zebrafish
telomere maintenance GO:0000723 1 0.030
regulation of kinase activity GO:0043549 15 0.030
negative regulation of response to stimulus GO:0048585 104 0.030
negative regulation of nuclear division GO:0051784 3 0.030
myeloid cell development GO:0061515 32 0.030
gtp catabolic process GO:0006184 2 0.030
oxoacid metabolic process GO:0043436 31 0.030
regulation of response to stress GO:0080134 36 0.030
ribose phosphate metabolic process GO:0019693 27 0.030
positive regulation of jnk cascade GO:0046330 3 0.030
negative regulation of signal transduction GO:0009968 94 0.030
Zebrafish Mouse
positive regulation of cell cycle GO:0045787 3 0.029
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.029
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.029
brain morphogenesis GO:0048854 18 0.029
cellular response to peptide GO:1901653 5 0.029
Mouse
epithelial cell differentiation GO:0030855 116 0.029
regulation of epithelial cell proliferation GO:0050678 3 0.029
localization of cell GO:0051674 244 0.029
regulation of reproductive process GO:2000241 4 0.028
purine containing compound metabolic process GO:0072521 29 0.028
renal tubule morphogenesis GO:0061333 1 0.028
response to hexose GO:0009746 3 0.028
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.028
positive regulation of nucleic acid templated transcription GO:1903508 57 0.028
cellular response to stress GO:0033554 62 0.027
carbohydrate derivative metabolic process GO:1901135 61 0.027
negative regulation of apoptotic process GO:0043066 55 0.027
cell morphogenesis GO:0000902 289 0.027
intracellular receptor signaling pathway GO:0030522 30 0.027
regulation of cytokine mediated signaling pathway GO:0001959 3 0.027
Zebrafish
regulation of cell development GO:0060284 100 0.027
organism emergence from protective structure GO:0071684 4 0.027
developmental programmed cell death GO:0010623 4 0.027
gtp metabolic process GO:0046039 4 0.027
inner ear receptor cell differentiation GO:0060113 29 0.026
regulation of cellular component organization GO:0051128 86 0.026
rhombomere 5 development GO:0021571 4 0.026
positive regulation of endothelial cell proliferation GO:0001938 1 0.026
response to decreased oxygen levels GO:0036293 25 0.026
Rat
amide biosynthetic process GO:0043604 1 0.026
multicellular organismal macromolecule metabolic process GO:0044259 2 0.026
regulation of gtp catabolic process GO:0033124 2 0.026
ameboidal type cell migration GO:0001667 143 0.025
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.025
regulation of anatomical structure morphogenesis GO:0022603 130 0.025
response to metal ion GO:0010038 34 0.025
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.025
mitotic cell cycle GO:0000278 64 0.025
negative regulation of jak stat cascade GO:0046426 1 0.025
Zebrafish
pyruvate metabolic process GO:0006090 1 0.025
positive regulation of cell differentiation GO:0045597 30 0.025
Mouse
regulation of sterol transport GO:0032371 3 0.025
regulation of carbohydrate biosynthetic process GO:0043255 1 0.024
response to hydrogen peroxide GO:0042542 3 0.024
digestive tract morphogenesis GO:0048546 231 0.024
nuclear export GO:0051168 1 0.024
negative regulation of nervous system development GO:0051961 22 0.024
erythrocyte homeostasis GO:0034101 55 0.024
myeloid leukocyte differentiation GO:0002573 15 0.024
ribonucleotide metabolic process GO:0009259 27 0.024
blood vessel morphogenesis GO:0048514 216 0.024
nitric oxide metabolic process GO:0046209 2 0.024
heart contraction GO:0060047 71 0.024
purine containing compound biosynthetic process GO:0072522 20 0.024
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.024
hydrogen peroxide metabolic process GO:0042743 2 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.024

socs3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.045
primary immunodeficiency disease DOID:612 0 0.032
immune system disease DOID:2914 0 0.032